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Conserved domains on  [gi|564361820|ref|XP_006242386|]
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autophagy-related protein 101 isoform X1 [Rattus norvegicus]

Protein Classification

autophagy-related protein 101( domain architecture ID 10545214)

autophagy-related protein 101 is required for autophagosome formation; it stabilizes ATG13, protecting it from proteasomal degradation

Gene Ontology:  GO:0006914|GO:0019901|GO:0000045
TCDB:  9.A.15

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ATG101 pfam07855
Autophagy-related protein 101; Atg101 is a critical autophagy factor that functions together ...
11-168 1.13e-56

Autophagy-related protein 101; Atg101 is a critical autophagy factor that functions together with ULK, Atg13 and FIP200. Atg101 has been shown to be a HORMA (Hop1, Rev7 and MAD2) domain protein with an open conformation.


:

Pssm-ID: 462290  Cd Length: 149  Bit Score: 176.58  E-value: 1.13e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564361820   11 SVEGRQVEEAMLAVLHTVLLHRSTGKFHYKkegtysigtvgiqdvDCDFIDFTYVRVSSEELDRALRKVVGEFKDALR-- 88
Cdd:pfam07855   1 TVERSQVRDVVKGILHTILFHRLFGKVRPK---------------DVDCLDLTYPRVDDPELERLIDEKVDAFVRALEss 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564361820   89 -NSGGDGLGQMSLEFYQKK-KSRW-PFSDECIPWEVWTVKVHVVALATEQERQICREKVGEKLCEKIINIVEVM-SRHEY 164
Cdd:pfam07855  66 sSSGGGGRGQISVQFYEKKrKKAWfGFKDEEVPWEQWTINVTVAPPRTESERQKVREALESSLQEALLKIITIVnERKDH 145

                  ....
gi 564361820  165 LPKM 168
Cdd:pfam07855 146 IPPI 149
 
Name Accession Description Interval E-value
ATG101 pfam07855
Autophagy-related protein 101; Atg101 is a critical autophagy factor that functions together ...
11-168 1.13e-56

Autophagy-related protein 101; Atg101 is a critical autophagy factor that functions together with ULK, Atg13 and FIP200. Atg101 has been shown to be a HORMA (Hop1, Rev7 and MAD2) domain protein with an open conformation.


Pssm-ID: 462290  Cd Length: 149  Bit Score: 176.58  E-value: 1.13e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564361820   11 SVEGRQVEEAMLAVLHTVLLHRSTGKFHYKkegtysigtvgiqdvDCDFIDFTYVRVSSEELDRALRKVVGEFKDALR-- 88
Cdd:pfam07855   1 TVERSQVRDVVKGILHTILFHRLFGKVRPK---------------DVDCLDLTYPRVDDPELERLIDEKVDAFVRALEss 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564361820   89 -NSGGDGLGQMSLEFYQKK-KSRW-PFSDECIPWEVWTVKVHVVALATEQERQICREKVGEKLCEKIINIVEVM-SRHEY 164
Cdd:pfam07855  66 sSSGGGGRGQISVQFYEKKrKKAWfGFKDEEVPWEQWTINVTVAPPRTESERQKVREALESSLQEALLKIITIVnERKDH 145

                  ....
gi 564361820  165 LPKM 168
Cdd:pfam07855 146 IPPI 149
 
Name Accession Description Interval E-value
ATG101 pfam07855
Autophagy-related protein 101; Atg101 is a critical autophagy factor that functions together ...
11-168 1.13e-56

Autophagy-related protein 101; Atg101 is a critical autophagy factor that functions together with ULK, Atg13 and FIP200. Atg101 has been shown to be a HORMA (Hop1, Rev7 and MAD2) domain protein with an open conformation.


Pssm-ID: 462290  Cd Length: 149  Bit Score: 176.58  E-value: 1.13e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564361820   11 SVEGRQVEEAMLAVLHTVLLHRSTGKFHYKkegtysigtvgiqdvDCDFIDFTYVRVSSEELDRALRKVVGEFKDALR-- 88
Cdd:pfam07855   1 TVERSQVRDVVKGILHTILFHRLFGKVRPK---------------DVDCLDLTYPRVDDPELERLIDEKVDAFVRALEss 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564361820   89 -NSGGDGLGQMSLEFYQKK-KSRW-PFSDECIPWEVWTVKVHVVALATEQERQICREKVGEKLCEKIINIVEVM-SRHEY 164
Cdd:pfam07855  66 sSSGGGGRGQISVQFYEKKrKKAWfGFKDEEVPWEQWTINVTVAPPRTESERQKVREALESSLQEALLKIITIVnERKDH 145

                  ....
gi 564361820  165 LPKM 168
Cdd:pfam07855 146 IPPI 149
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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