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Conserved domains on  [gi|564368623|ref|XP_006245091|]
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INO80 complex subunit D isoform X1 [Rattus norvegicus]

Protein Classification

zf-C3Hc3H domain-containing protein( domain architecture ID 10620855)

zf-C3Hc3H domain-containing protein may be a DNA-binding protein and is similar to human KAT8 regulatory NSL complex subunit 2 that, as part of the NSL complex, is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 442-506 1.12e-20

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


:

Pssm-ID: 464023  Cd Length: 62  Bit Score: 86.25  E-value: 1.12e-20
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564368623   442 CSGtvkGEQCTNQALPFTRHCFQHILLNRSQQLFSSCTAKFADGQQCSVPVFDITHQTPLCEEHA 506
Cdd:pfam13891    1 CSY---GVGCKQKALPGTKYCYRHILEDPNQALFKQCSYVFSGNKRCGNPVLKSDVPSPLCPEHA 62
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 18-79 3.11e-17

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


:

Pssm-ID: 464023  Cd Length: 62  Bit Score: 76.62  E-value: 3.11e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564368623    18 CSYSPKlCKQRRLNGYAFCIRHVLEDKT-APFKQCEYVAKYNSqRCTNPIPKSE-DRRYCNSHL 79
Cdd:pfam13891    1 CSYGVG-CKQKALPGTKYCYRHILEDPNqALFKQCSYVFSGNK-RCGNPVLKSDvPSPLCPEHA 62
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
170-285 1.21e-04

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK14971:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 614  Bit Score: 45.92  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368623  170 LQSKLAQNRQRQRETEILKVRQ----EHFSTPPTPPQQHahLSPLPTSLKPPAPPQGSVCKSPQPQSTSLPMQGVAP--- 242
Cdd:PRK14971  340 LNYRASKNKRLLVELTLIQLAQltqkGDDASGGRGPKQH--IKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPqsa 417

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 564368623  243 -TTHSIAQTRQASHKRPLPLLPSSRAPVSDTPRTDRILMKATAF 285
Cdd:PRK14971  418 tQPAGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPVS 461
 
Name Accession Description Interval E-value
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 442-506 1.12e-20

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 86.25  E-value: 1.12e-20
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564368623   442 CSGtvkGEQCTNQALPFTRHCFQHILLNRSQQLFSSCTAKFADGQQCSVPVFDITHQTPLCEEHA 506
Cdd:pfam13891    1 CSY---GVGCKQKALPGTKYCYRHILEDPNQALFKQCSYVFSGNKRCGNPVLKSDVPSPLCPEHA 62
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 18-79 3.11e-17

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 76.62  E-value: 3.11e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564368623    18 CSYSPKlCKQRRLNGYAFCIRHVLEDKT-APFKQCEYVAKYNSqRCTNPIPKSE-DRRYCNSHL 79
Cdd:pfam13891    1 CSYGVG-CKQKALPGTKYCYRHILEDPNqALFKQCSYVFSGNK-RCGNPVLKSDvPSPLCPEHA 62
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
170-285 1.21e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 45.92  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368623  170 LQSKLAQNRQRQRETEILKVRQ----EHFSTPPTPPQQHahLSPLPTSLKPPAPPQGSVCKSPQPQSTSLPMQGVAP--- 242
Cdd:PRK14971  340 LNYRASKNKRLLVELTLIQLAQltqkGDDASGGRGPKQH--IKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPqsa 417

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 564368623  243 -TTHSIAQTRQASHKRPLPLLPSSRAPVSDTPRTDRILMKATAF 285
Cdd:PRK14971  418 tQPAGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPVS 461
Spc29 pfam17082
Spindle Pole Component 29; Spc29 is a component of the Spc-110 subcomplex and is required for ...
 166-278 8.52e-04

Spindle Pole Component 29; Spc29 is a component of the Spc-110 subcomplex and is required for the SPB (Spindle pole body) duplication. Spc29 acts as a linker between the central plaque component Spc42 to the inner plaque component Spc110.


Pssm-ID: 293687  Cd Length: 245  Bit Score: 42.27  E-value: 8.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368623   166 VRKKLQSKLAQNRQRQRETEILKVRQEHFSTPPTPPQQHAHLSPLPTSLKPPAPPQGSVCKSPQPQSTSLPMQgvaptth 245
Cdd:pfam17082   10 ADKKFQDDTLNNIRKEYLESKKKLRELEFSSKPSELQKHYRAANEMSSPLHRLSYTGKSDDRKVPTPLDDKLR------- 82

                           90       100       110
                   ....*....|....*....|....*....|...
gi 564368623   246 siAQTRQASHKRPLPLLPSSRAPVSDTPRTDRI 278
Cdd:pfam17082   83 --RQLREGNSRKPPPKISSPGMPPSDRSRLDRI 113
 
Name Accession Description Interval E-value
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 442-506 1.12e-20

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 86.25  E-value: 1.12e-20
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564368623   442 CSGtvkGEQCTNQALPFTRHCFQHILLNRSQQLFSSCTAKFADGQQCSVPVFDITHQTPLCEEHA 506
Cdd:pfam13891    1 CSY---GVGCKQKALPGTKYCYRHILEDPNQALFKQCSYVFSGNKRCGNPVLKSDVPSPLCPEHA 62
zf-C3Hc3H pfam13891
Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin ...
 18-79 3.11e-17

Potential DNA-binding domain; This domain is likely to be the DNA-binding domain of chromatin re-modelling proteins and helicases.


Pssm-ID: 464023  Cd Length: 62  Bit Score: 76.62  E-value: 3.11e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564368623    18 CSYSPKlCKQRRLNGYAFCIRHVLEDKT-APFKQCEYVAKYNSqRCTNPIPKSE-DRRYCNSHL 79
Cdd:pfam13891    1 CSYGVG-CKQKALPGTKYCYRHILEDPNqALFKQCSYVFSGNK-RCGNPVLKSDvPSPLCPEHA 62
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
170-285 1.21e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 45.92  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368623  170 LQSKLAQNRQRQRETEILKVRQ----EHFSTPPTPPQQHahLSPLPTSLKPPAPPQGSVCKSPQPQSTSLPMQGVAP--- 242
Cdd:PRK14971  340 LNYRASKNKRLLVELTLIQLAQltqkGDDASGGRGPKQH--IKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPqsa 417

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 564368623  243 -TTHSIAQTRQASHKRPLPLLPSSRAPVSDTPRTDRILMKATAF 285
Cdd:PRK14971  418 tQPAGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPVS 461
Spc29 pfam17082
Spindle Pole Component 29; Spc29 is a component of the Spc-110 subcomplex and is required for ...
 166-278 8.52e-04

Spindle Pole Component 29; Spc29 is a component of the Spc-110 subcomplex and is required for the SPB (Spindle pole body) duplication. Spc29 acts as a linker between the central plaque component Spc42 to the inner plaque component Spc110.


Pssm-ID: 293687  Cd Length: 245  Bit Score: 42.27  E-value: 8.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368623   166 VRKKLQSKLAQNRQRQRETEILKVRQEHFSTPPTPPQQHAHLSPLPTSLKPPAPPQGSVCKSPQPQSTSLPMQgvaptth 245
Cdd:pfam17082   10 ADKKFQDDTLNNIRKEYLESKKKLRELEFSSKPSELQKHYRAANEMSSPLHRLSYTGKSDDRKVPTPLDDKLR------- 82

                           90       100       110
                   ....*....|....*....|....*....|...
gi 564368623   246 siAQTRQASHKRPLPLLPSSRAPVSDTPRTDRI 278
Cdd:pfam17082   83 --RQLREGNSRKPPPKISSPGMPPSDRSRLDRI 113
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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