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Conserved domains on  [gi|564373371|ref|XP_006247021|]
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peroxisomal sarcosine oxidase isoform X2 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
soxA_mon super family cl31099
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 8-335 0e+00

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


The actual alignment was detected with superfamily member TIGR01377:

Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 567.92  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371    8 WDAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPHSRGSSHGQSRIIRKAYPEDFYTRMMDECYRTWAQLEREAGAQLH 87
Cdd:TIGR01377   1 FDVIVVGAGIMGCFAAYHLAKHGKKTLLLEQFDLPHSRGSSHGQSRIIRKAYPEDFYTPMMLECYQLWAQLEKEAGTKLH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   88 RRTELLFLGMKENPGLKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGEVGLLDKTGGVLYADKALRALQHVIRQLGG 167
Cdd:TIGR01377  81 RQTGLLLLGPKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRALQELAEAHGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  168 MVCDGEKVVEIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRILRPLGIELPLQTLRINVCYWREKVPGSYSVSQAFPCI 246
Cdd:TIGR01377 161 TVRDGTKVVEIEPtELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPLRINVCYWREKEPGSYGVSQAFPCF 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  247 LSLDLAPhHIYGLPASEYPGLMK----------------------------------------------------NTPDE 274
Cdd:TIGR01377 241 LVLGLNP-HIYGLPSFEYPGLMKvyyhhgqqidpderdcpfgadiedvqilrkfvrdhlpglngepkkgevcmytNTPDE 319

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564373371  275 HFILDCHPKYDNIVIGAGFSGHGFKLAPAVGKVLYELSMKLPPSYDLAPFRISRFSKLSKA 335
Cdd:TIGR01377 320 HFVIDLHPKYDNVVIGAGFSGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRFALKKKA 380
 
Name Accession Description Interval E-value
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 8-335 0e+00

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 567.92  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371    8 WDAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPHSRGSSHGQSRIIRKAYPEDFYTRMMDECYRTWAQLEREAGAQLH 87
Cdd:TIGR01377   1 FDVIVVGAGIMGCFAAYHLAKHGKKTLLLEQFDLPHSRGSSHGQSRIIRKAYPEDFYTPMMLECYQLWAQLEKEAGTKLH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   88 RRTELLFLGMKENPGLKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGEVGLLDKTGGVLYADKALRALQHVIRQLGG 167
Cdd:TIGR01377  81 RQTGLLLLGPKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRALQELAEAHGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  168 MVCDGEKVVEIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRILRPLGIELPLQTLRINVCYWREKVPGSYSVSQAFPCI 246
Cdd:TIGR01377 161 TVRDGTKVVEIEPtELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPLRINVCYWREKEPGSYGVSQAFPCF 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  247 LSLDLAPhHIYGLPASEYPGLMK----------------------------------------------------NTPDE 274
Cdd:TIGR01377 241 LVLGLNP-HIYGLPSFEYPGLMKvyyhhgqqidpderdcpfgadiedvqilrkfvrdhlpglngepkkgevcmytNTPDE 319

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564373371  275 HFILDCHPKYDNIVIGAGFSGHGFKLAPAVGKVLYELSMKLPPSYDLAPFRISRFSKLSKA 335
Cdd:TIGR01377 320 HFVIDLHPKYDNVVIGAGFSGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRFALKKKA 380
solA PRK11259
N-methyl-L-tryptophan oxidase;
9-330 1.47e-80

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 249.75  E-value: 1.47e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   9 DAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPHSRGSSHGQSRIIRKAYPED-FYTRMMDECYRTWAQLEREAGAQLH 87
Cdd:PRK11259   5 DVIVIGLGSMGSAAGYYLARRGLRVLGLDRFMPPHQQGSSHGDTRIIRHAYGEGpAYVPLVLRAQELWRELERESGEPLF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  88 RRTELLFLGMKENPGLKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGEVGLLDKTGGVLYADKALRALQHVIRQLGG 167
Cdd:PRK11259  85 VRTGVLNLGPADSDFLANSIRSARQHGLPHEVLDAAEIRRRFPQFRLPDGYIALFEPDGGFLRPELAIKAHLRLAREAGA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371 168 MVCDGEKVVEIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRILRPLGieLPLQTLRiNVCYWREKVPGsYSVSQAFPcI 246
Cdd:PRK11259 165 ELLFNEPVTAIEAdGDGVTVTTADGTYEAKKLVVSAGAWVKDLLPPLE--LPLTPVR-QVLAWFQADGR-YSEPNRFP-A 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371 247 LSLDLAP-HHIYGLPASEYPGL--------------------------------------------MK-------NTPDE 274
Cdd:PRK11259 240 FIWEVPDgDQYYGFPAENGPGLkigkhnggqeitspderdrfvtvaedgaelrpflrnylpgvgpcLRgaactytNTPDE 319

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 564373371 275 HFILDCHPKYDNIVIGAGFSGHGFKLAPAVGKVLYELSMKLPPSYDLAPFRISRFS 330
Cdd:PRK11259 320 HFIIDTLPGHPNVLVASGCSGHGFKFASVLGEILADLAQDGTSDFDLSPFSLSRFA 375
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
9-328 7.68e-55

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 183.18  E-value: 7.68e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   9 DAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPhsRGSSHGQSRIIRKAYPED---FYTRMMDECYRTWAQLEREAGAQ 85
Cdd:COG0665    4 DVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPG--SGASGRNAGQLRPGLAALadrALVRLAREALDLWRELAAELGID 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  86 L-HRRTELLFLGMKENP--GLKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGEVGLLDKTGGVLYADKALRALQHVI 162
Cdd:COG0665   82 CdFRRTGVLYLARTEAElaALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALARAA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371 163 RQLGGMVCDGEKVVEIRP--GLPVTVKTTLKSYQANSLVITAGPWTNRILRPLGIELPLQTLRinvcywrekvpgSYSVs 240
Cdd:COG0665  162 RAAGVRIREGTPVTGLERegGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVR------------GYVL- 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371 241 qAFPCILSLDLAP----HHIYGLPASE---------------------------------YPGLMK------------NT 271
Cdd:COG0665  229 -VTEPLPDLPLRPvlddTGVYLRPTADgrllvggtaepagfdraptperleallrrlrrlFPALADaeivrawaglrpMT 307

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 564373371 272 PDEHFILDCHPKYDNIVIGAGFSGHGFKLAPAVGKVLYELSMKLPPSYDLAPFRISR 328
Cdd:COG0665  308 PDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 9-311 1.84e-40

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 144.85  E-value: 1.84e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371    9 DAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPhSRGSSHGQSRIIR---KAYPEDFYTRMMDECYRTWAQLEREAGAQ 85
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDP-GSGASGRNAGLIHpglRYLEPSELARLALEALDLWEELEEELGID 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   86 L-HRRTELLFLGMKE-NPGLKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGevGLLDKTGGVLYADKALRALQHVIR 163
Cdd:pfam01266  80 CgFRRCGVLVLARDEeEEALEKLLAALRRLGVPAELLDAEELRELEPLLPGLRG--GLFYPDGGHVDPARLLRALARAAE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  164 QLGGMVCDGEKVVEIRPGLPVTVKTTLKSYQAnsLVITAGPWTnRILRPLGIELPLQTLR---INVCYWREKV---PGSY 237
Cdd:pfam01266 158 ALGVRIIEGTEVTGIEEEGGVWGVVTTGEADA--VVNAAGAWA-DLLALPGLRLPVRPVRgqvLVLEPLPEALlilPVPI 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  238 SVSQAFPCILSLDLAPHHIYG------------LPASEYPGLMKN--------------------TPDEHFILDcHPKYD 285
Cdd:pfam01266 235 TVDPGRGVYLRPRADGRLLLGgtdeedgfddptPDPEEIEELLEAarrlfpaladierawaglrpLPDGLPIIG-RPGSP 313

                         330       340
                  ....*....|....*....|....*.
gi 564373371  286 NIVIGAGFSGHGFKLAPAVGKVLYEL 311
Cdd:pfam01266 314 GLYLATGHGGHGLTLAPGIGKLLAEL 339
 
Name Accession Description Interval E-value
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 8-335 0e+00

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 567.92  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371    8 WDAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPHSRGSSHGQSRIIRKAYPEDFYTRMMDECYRTWAQLEREAGAQLH 87
Cdd:TIGR01377   1 FDVIVVGAGIMGCFAAYHLAKHGKKTLLLEQFDLPHSRGSSHGQSRIIRKAYPEDFYTPMMLECYQLWAQLEKEAGTKLH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   88 RRTELLFLGMKENPGLKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGEVGLLDKTGGVLYADKALRALQHVIRQLGG 167
Cdd:TIGR01377  81 RQTGLLLLGPKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRALQELAEAHGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  168 MVCDGEKVVEIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRILRPLGIELPLQTLRINVCYWREKVPGSYSVSQAFPCI 246
Cdd:TIGR01377 161 TVRDGTKVVEIEPtELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPLRINVCYWREKEPGSYGVSQAFPCF 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  247 LSLDLAPhHIYGLPASEYPGLMK----------------------------------------------------NTPDE 274
Cdd:TIGR01377 241 LVLGLNP-HIYGLPSFEYPGLMKvyyhhgqqidpderdcpfgadiedvqilrkfvrdhlpglngepkkgevcmytNTPDE 319

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564373371  275 HFILDCHPKYDNIVIGAGFSGHGFKLAPAVGKVLYELSMKLPPSYDLAPFRISRFSKLSKA 335
Cdd:TIGR01377 320 HFVIDLHPKYDNVVIGAGFSGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRFALKKKA 380
solA PRK11259
N-methyl-L-tryptophan oxidase;
9-330 1.47e-80

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 249.75  E-value: 1.47e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   9 DAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPHSRGSSHGQSRIIRKAYPED-FYTRMMDECYRTWAQLEREAGAQLH 87
Cdd:PRK11259   5 DVIVIGLGSMGSAAGYYLARRGLRVLGLDRFMPPHQQGSSHGDTRIIRHAYGEGpAYVPLVLRAQELWRELERESGEPLF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  88 RRTELLFLGMKENPGLKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGEVGLLDKTGGVLYADKALRALQHVIRQLGG 167
Cdd:PRK11259  85 VRTGVLNLGPADSDFLANSIRSARQHGLPHEVLDAAEIRRRFPQFRLPDGYIALFEPDGGFLRPELAIKAHLRLAREAGA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371 168 MVCDGEKVVEIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRILRPLGieLPLQTLRiNVCYWREKVPGsYSVSQAFPcI 246
Cdd:PRK11259 165 ELLFNEPVTAIEAdGDGVTVTTADGTYEAKKLVVSAGAWVKDLLPPLE--LPLTPVR-QVLAWFQADGR-YSEPNRFP-A 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371 247 LSLDLAP-HHIYGLPASEYPGL--------------------------------------------MK-------NTPDE 274
Cdd:PRK11259 240 FIWEVPDgDQYYGFPAENGPGLkigkhnggqeitspderdrfvtvaedgaelrpflrnylpgvgpcLRgaactytNTPDE 319

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 564373371 275 HFILDCHPKYDNIVIGAGFSGHGFKLAPAVGKVLYELSMKLPPSYDLAPFRISRFS 330
Cdd:PRK11259 320 HFIIDTLPGHPNVLVASGCSGHGFKFASVLGEILADLAQDGTSDFDLSPFSLSRFA 375
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
9-328 7.68e-55

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 183.18  E-value: 7.68e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   9 DAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPhsRGSSHGQSRIIRKAYPED---FYTRMMDECYRTWAQLEREAGAQ 85
Cdd:COG0665    4 DVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPG--SGASGRNAGQLRPGLAALadrALVRLAREALDLWRELAAELGID 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  86 L-HRRTELLFLGMKENP--GLKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGEVGLLDKTGGVLYADKALRALQHVI 162
Cdd:COG0665   82 CdFRRTGVLYLARTEAElaALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALARAA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371 163 RQLGGMVCDGEKVVEIRP--GLPVTVKTTLKSYQANSLVITAGPWTNRILRPLGIELPLQTLRinvcywrekvpgSYSVs 240
Cdd:COG0665  162 RAAGVRIREGTPVTGLERegGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVR------------GYVL- 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371 241 qAFPCILSLDLAP----HHIYGLPASE---------------------------------YPGLMK------------NT 271
Cdd:COG0665  229 -VTEPLPDLPLRPvlddTGVYLRPTADgrllvggtaepagfdraptperleallrrlrrlFPALADaeivrawaglrpMT 307

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 564373371 272 PDEHFILDCHPKYDNIVIGAGFSGHGFKLAPAVGKVLYELSMKLPPSYDLAPFRISR 328
Cdd:COG0665  308 PDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 9-311 1.84e-40

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 144.85  E-value: 1.84e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371    9 DAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPhSRGSSHGQSRIIR---KAYPEDFYTRMMDECYRTWAQLEREAGAQ 85
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDP-GSGASGRNAGLIHpglRYLEPSELARLALEALDLWEELEEELGID 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   86 L-HRRTELLFLGMKE-NPGLKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGevGLLDKTGGVLYADKALRALQHVIR 163
Cdd:pfam01266  80 CgFRRCGVLVLARDEeEEALEKLLAALRRLGVPAELLDAEELRELEPLLPGLRG--GLFYPDGGHVDPARLLRALARAAE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  164 QLGGMVCDGEKVVEIRPGLPVTVKTTLKSYQAnsLVITAGPWTnRILRPLGIELPLQTLR---INVCYWREKV---PGSY 237
Cdd:pfam01266 158 ALGVRIIEGTEVTGIEEEGGVWGVVTTGEADA--VVNAAGAWA-DLLALPGLRLPVRPVRgqvLVLEPLPEALlilPVPI 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  238 SVSQAFPCILSLDLAPHHIYG------------LPASEYPGLMKN--------------------TPDEHFILDcHPKYD 285
Cdd:pfam01266 235 TVDPGRGVYLRPRADGRLLLGgtdeedgfddptPDPEEIEELLEAarrlfpaladierawaglrpLPDGLPIIG-RPGSP 313

                         330       340
                  ....*....|....*....|....*.
gi 564373371  286 NIVIGAGFSGHGFKLAPAVGKVLYEL 311
Cdd:pfam01266 314 GLYLATGHGGHGLTLAPGIGKLLAEL 339
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
9-267 5.54e-13

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 69.02  E-value: 5.54e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   9 DAIVIGAGVQGCFTAYHLAQ-NSKKVLLLEQflLPH-SRGSSHGQSRIIRKAYPEDFYTRMMDECYRTWAQLEREAgAQL 86
Cdd:COG0579    6 DVVIIGAGIVGLALARELSRyEDLKVLVLEK--EDDvAQESSGNNSGVIHAGLYYTPGSLKARLCVEGNELFYELC-REL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  87 ---HRRTELLFLGMKEN--PGLKTIQATLSRQGIDH-ECLSSVHLKQRFPNIRfTKGEVGLLDKTGGVLYADKALRALQH 160
Cdd:COG0579   83 gipFKRCGKLVVATGEEevAFLEKLYERGKANGVPGlEILDREELRELEPLLS-DEGVAALYSPSTGIVDPGALTRALAE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371 161 VIRQLGGMVCDGEKVVEIRP---GlpVTVKTTLKSYQANSLVITAGPWTNRILRPLGIELPLQTlrinvcywrekVP--G 235
Cdd:COG0579  162 NAEANGVELLLNTEVTGIERegdG--WEVTTNGGTIRARFVINAAGLYADRLAQMAGIGKDFGI-----------FPvkG 228

                        250       260       270
                 ....*....|....*....|....*....|....
gi 564373371 236 SYsvsqafpCILS--LDLAPHHIYGLPASEYPGL 267
Cdd:COG0579  229 EY-------LVLDkpAELVNAKVYPVPDPGAPFL 255
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
98-220 1.01e-06

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 49.82  E-value: 1.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371  98 KENPGLKTIQATLSRQGIDHECLSSVHLKQRFPNIRftkGEVGLL-DKTGGVLYADKAlRALQHVIRQLGGMVCDGEKVV 176
Cdd:PRK11728  98 LELERMEALYERARANGIEVERLDAEELREREPNIR---GLGAIFvPSTGIVDYRAVA-EAMAELIQARGGEIRLGAEVT 173

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 564373371 177 EIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRILRPLGIELPLQ 220
Cdd:PRK11728 174 ALDEhANGVVVRTTQGEYEARTLINCAGLMSDRLAKMAGLEPDFR 218
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 8-93 2.64e-06

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 48.47  E-value: 2.64e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371    8 WDAIVIGAGVQGCFTAYHLAQNSKKVLLLE--------------------QFLLPHS------RGS---SHGQSRIIRKA 58
Cdd:TIGR02032   1 YDVVVVGAGPAGASAAYRLADKGLRVLLLEkksfprykpcggalspraleELDLPGElivnlvRGArffSPNGDSVEIPI 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 564373371   59 YPEDFYT--RM-MDECYRTWAQlerEAGAQLHRRTELL 93
Cdd:TIGR02032  81 ETELAYVidRDaFDEQLAERAQ---EAGAELRLGTRVL 115
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 9-87 4.48e-06

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 48.30  E-value: 4.48e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   9 DAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPHSRGSSHGQ--------------SRIIRKAYpedFYTRmmdecyRT 74
Cdd:PRK01747 262 DAAIIGGGIAGAALALALARRGWQVTLYEADEAPAQGASGNRQgalypllskddnalSRFFRAAF---LFAR------RF 332

                         90
                 ....*....|...
gi 564373371  75 WAQLEREAGAQLH 87
Cdd:PRK01747 333 YDALPAAGVAFDH 345
HpnW_proposed TIGR03364
FAD dependent oxidoreductase TIGR03364; This clade of FAD dependent oxidoreductases (members ...
 9-203 1.18e-05

FAD dependent oxidoreductase TIGR03364; This clade of FAD dependent oxidoreductases (members of the pfam01266 family) is syntenically associated with a family of proposed phosphonatase-like enzymes (TIGR03351) and is also found (less frequently) in association with phosphonate transporter components. A likely role for this enzyme involves the oxidative deamination of an aminophosphonate differring slightly from 2-aminoethylphosphonate, possibly 1-hydroxy-2-aminoethylphosphonate (see the comments for TIGR03351). Many members of the larger FAD dependent oxidoreductase family act as amino acid oxidative deaminases.


Pssm-ID: 132407 [Multi-domain]  Cd Length: 365  Bit Score: 46.52  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371    9 DAIVIGAGVQGCFTAYHLAQNSKKVLLLEQflLPHSRGSS---HGQSRIIRKAyPEDFYTRMMdECYRTWAQLEREAGAQ 85
Cdd:TIGR03364   2 DLIIVGAGILGLAHAYAAARRGLSVTVIER--SSRAQGASvrnFGQVWPTGQA-PGPAWDRAR-RSREIWLELAAKAGIW 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564373371   86 LhRRTELLFLGMKEnPGLKTIQ---ATLSRQGIDHECLSSVHLKQRFPNIRFTKGEVGLLDKTGGVLYADKALRALQHVI 162
Cdd:TIGR03364  78 V-RENGSLHLARTE-EELAVLEefaATREPAEYRVELLTPAEVAAKFPALRLDGLRGGLHSPDELRVEPREAIPALAAYL 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 564373371  163 RQLGGMvcD---GEKVVEIRPGlpvTVKTTLKSYQANSLVITAG 203
Cdd:TIGR03364 156 AEQHGV--EfhwNTAVTSVETG---TVRTSRGDVHADQVFVCPG 194
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 9-38 6.20e-04

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 41.42  E-value: 6.20e-04
                         10        20        30
                 ....*....|....*....|....*....|
gi 564373371   9 DAIVIGAGVQGCFTAYHLAQNSKKVLLLEQ 38
Cdd:PRK12834   6 DVIVVGAGLAGLVAAAELADAGKRVLLLDQ 35
COG3573 COG3573
Predicted oxidoreductase [General function prediction only];
9-38 1.14e-03

Predicted oxidoreductase [General function prediction only];


Pssm-ID: 442794 [Multi-domain]  Cd Length: 551  Bit Score: 40.55  E-value: 1.14e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 564373371   9 DAIVIGAGVQGCFTAYHLAQNSKKVLLLEQ 38
Cdd:COG3573    7 DVIVVGAGLAGLVAAAELADAGRRVLLLDQ 36
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 8-37 1.48e-03

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 40.20  E-value: 1.48e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 564373371   8 WDAIVIGAGVQGCFTAYHLAQN-SKKVLLLE 37
Cdd:COG2303    5 YDYVIVGAGSAGCVLANRLSEDaGLRVLLLE 35
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
12-38 1.80e-03

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 36.36  E-value: 1.80e-03
                          10        20
                  ....*....|....*....|....*..
gi 564373371   12 VIGAGVQGCFTAYHLAQNSKKVLLLEQ 38
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEK 27
PRK10015 PRK10015
oxidoreductase; Provisional
 6-50 4.36e-03

oxidoreductase; Provisional


Pssm-ID: 182194 [Multi-domain]  Cd Length: 429  Bit Score: 38.80  E-value: 4.36e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 564373371   6 DLWDAIVIGAGVQGCFTAYHLAQNSKKVLLLEqfllphsRGSSHG 50
Cdd:PRK10015   4 DKFDAIVVGAGVAGSVAALVMARAGLDVLVIE-------RGDSAG 41
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 8-40 5.99e-03

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 38.29  E-value: 5.99e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 564373371   8 WDAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFL 40
Cdd:PTZ00367  34 YDVIIVGGSIAGPVLAKALSKQGRKVLMLERDL 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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