|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
14-289 |
6.17e-36 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 132.73 E-value: 6.17e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 14 VLRGTQSAVNTLHFCPapgaaENPLLFSGSQNGLVHIWSLQTRRIVATLNGHGGqGVTWLKTLPQGQQLLSQGRDPRLCL 93
Cdd:COG2319 157 TLTGHSGAVTSVAFSP-----DGKLLASGSDDGTVRLWDLATGKLLRTLTGHTG-AVRSVAFSPDGKLLASGSADGTVRL 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 94 WDLAEGRNTVMDSVQLDSVgfckssilvrgqlcWMLAVPGKGSdetnsslrpLLLAGYEDGSVTLWDVSERKVCSQITCH 173
Cdd:COG2319 231 WDLATGKLLRTLTGHSGSV--------------RSVAFSPDGR---------LLASGSADGTVRLWDLATGELLRTLTGH 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 174 EEPVMGLDF--DSQKAkgVSGSAGKVLAVWSLDDQQSLQVKKTHeliNPGIAEVTLRPDHRLFATAGWDHRIRVFHWRTI 251
Cdd:COG2319 288 SGGVNSVAFspDGKLL--ASGSDDGTVRLWDLATGKLLRTLTGH---TGAVRSVAFSPDGKTLASGSDDGTVRLWDLATG 362
|
250 260 270
....*....|....*....|....*....|....*....
gi 564377665 252 KPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWSL 289
Cdd:COG2319 363 ELLRTLTGHTGAVTSVAFSPDGrTLASGSADGTVRLWDL 401
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
12-288 |
5.56e-34 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 125.14 E-value: 5.56e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 12 RFVLRGTQSAVNTLHFCPapgaaENPLLFSGSQNGLVHIWSLQTRRIVATLNGHGGqGVTWLKTLPQGQQLLSQGRDPRL 91
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSP-----DGKLLATGSGDGTIKVWDLETGELLRTLKGHTG-PVRDVAASADGTYLASGSSDKTI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 92 CLWDLAEGR---------NTVMD-----------------SVQLDSVGFCKSSILVRGQLCWMLAVPGKGSDetnsslrP 145
Cdd:cd00200 76 RLWDLETGEcvrtltghtSYVSSvafspdgrilssssrdkTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDG-------T 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 146 LLLAGYEDGSVTLWDVSERKVCSQITCHEEPVMGLDFDSQKAKGVSGSAGKVLAVWSLDDQQSLQVKKTHElinPGIAEV 225
Cdd:cd00200 149 FVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHE---NGVNSV 225
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564377665 226 TLRPDHRLFATAGWDHRIRVFHWRTIKPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWS 288
Cdd:cd00200 226 AFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGkRLASGSADGTIRIWD 289
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
125-289 |
2.25e-08 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 55.09 E-value: 2.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 125 LCWmlavpgkgsdetNSSLRPLLLAGYEDGSVTLWDVSERKVCSQITCHEEPVMGLDFDSQKAKGV-SGSAGKVLAVWSL 203
Cdd:PLN00181 538 ICW------------NSYIKSQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSADPTLLaSGSDDGSVKLWSI 605
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 204 DDQQSLQVKKTheliNPGIAEVTLRPDH-RLFATAGWDHRIRVFHWRTIK-PLAVLAFHSAPVHCVAFAADGLLAAGSKD 281
Cdd:PLN00181 606 NQGVSIGTIKT----KANICCVQFPSESgRSLAFGSADHKVYYYDLRNPKlPLCTMIGHSKTVSYVRFVDSSTLVSSSTD 681
|
....*...
gi 564377665 282 QRISVWSL 289
Cdd:PLN00181 682 NTLKLWDL 689
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
250-288 |
1.57e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 41.14 E-value: 1.57e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 564377665 250 TIKPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWS 288
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGkYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
252-288 |
9.43e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 38.87 E-value: 9.43e-05
10 20 30
....*....|....*....|....*....|....*...
gi 564377665 252 KPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWS 288
Cdd:pfam00400 2 KLLKTLEGHTGSVTSLAFSPDGkLLASGSDDGTVKVWD 39
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
14-289 |
6.17e-36 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 132.73 E-value: 6.17e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 14 VLRGTQSAVNTLHFCPapgaaENPLLFSGSQNGLVHIWSLQTRRIVATLNGHGGqGVTWLKTLPQGQQLLSQGRDPRLCL 93
Cdd:COG2319 157 TLTGHSGAVTSVAFSP-----DGKLLASGSDDGTVRLWDLATGKLLRTLTGHTG-AVRSVAFSPDGKLLASGSADGTVRL 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 94 WDLAEGRNTVMDSVQLDSVgfckssilvrgqlcWMLAVPGKGSdetnsslrpLLLAGYEDGSVTLWDVSERKVCSQITCH 173
Cdd:COG2319 231 WDLATGKLLRTLTGHSGSV--------------RSVAFSPDGR---------LLASGSADGTVRLWDLATGELLRTLTGH 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 174 EEPVMGLDF--DSQKAkgVSGSAGKVLAVWSLDDQQSLQVKKTHeliNPGIAEVTLRPDHRLFATAGWDHRIRVFHWRTI 251
Cdd:COG2319 288 SGGVNSVAFspDGKLL--ASGSDDGTVRLWDLATGKLLRTLTGH---TGAVRSVAFSPDGKTLASGSDDGTVRLWDLATG 362
|
250 260 270
....*....|....*....|....*....|....*....
gi 564377665 252 KPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWSL 289
Cdd:COG2319 363 ELLRTLTGHTGAVTSVAFSPDGrTLASGSADGTVRLWDL 401
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
12-289 |
6.18e-35 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 130.03 E-value: 6.18e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 12 RFVLRGTQSAVNTLHFcpapgAAENPLLFSGSQNGLVHIWSLQTRRIVATLNGHGGqGVTWLKTLPQGQQLLSQGRDPRL 91
Cdd:COG2319 113 LRTLTGHTGAVRSVAF-----SPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSG-AVTSVAFSPDGKLLASGSDDGTV 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 92 CLWDLAEGRntvmdsvqldsvgfCKSSILVRGQLCWMLAVPGKGSdetnsslrpLLLAGYEDGSVTLWDVSERKVCSQIT 171
Cdd:COG2319 187 RLWDLATGK--------------LLRTLTGHTGAVRSVAFSPDGK---------LLASGSADGTVRLWDLATGKLLRTLT 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 172 CHEEPVMGLDF--DSQKAkgVSGSAGKVLAVWSLDDQQSLQVKKTHeliNPGIAEVTLRPDHRLFATAGWDHRIRVFHWR 249
Cdd:COG2319 244 GHSGSVRSVAFspDGRLL--ASGSADGTVRLWDLATGELLRTLTGH---SGGVNSVAFSPDGKLLASGSDDGTVRLWDLA 318
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 564377665 250 TIKPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWSL 289
Cdd:COG2319 319 TGKLLRTLTGHTGAVRSVAFSPDGkTLASGSDDGTVRLWDL 359
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
12-288 |
5.56e-34 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 125.14 E-value: 5.56e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 12 RFVLRGTQSAVNTLHFCPapgaaENPLLFSGSQNGLVHIWSLQTRRIVATLNGHGGqGVTWLKTLPQGQQLLSQGRDPRL 91
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSP-----DGKLLATGSGDGTIKVWDLETGELLRTLKGHTG-PVRDVAASADGTYLASGSSDKTI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 92 CLWDLAEGR---------NTVMD-----------------SVQLDSVGFCKSSILVRGQLCWMLAVPGKGSDetnsslrP 145
Cdd:cd00200 76 RLWDLETGEcvrtltghtSYVSSvafspdgrilssssrdkTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDG-------T 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 146 LLLAGYEDGSVTLWDVSERKVCSQITCHEEPVMGLDFDSQKAKGVSGSAGKVLAVWSLDDQQSLQVKKTHElinPGIAEV 225
Cdd:cd00200 149 FVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHE---NGVNSV 225
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564377665 226 TLRPDHRLFATAGWDHRIRVFHWRTIKPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWS 288
Cdd:cd00200 226 AFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGkRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
2-289 |
1.35e-31 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 121.17 E-value: 1.35e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 2 AAPFPPPPSPRFVLRGTQSAVNTLHFCPAPGaaenpLLFSGSQNGLVHIWSLQTRRIVATLNGHGGqGVTWLKTLPQGQQ 81
Cdd:COG2319 61 LLLDAAAGALLATLLGHTAAVLSVAFSPDGR-----LLASASADGTVRLWDLATGLLLRTLTGHTG-AVRSVAFSPDGKT 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 82 LLSQGRDPRLCLWDLAEGRntvmdsvqldsvgfCKSSILVRGQLCWMLAVPGKGSdetnsslrpLLLAGYEDGSVTLWDV 161
Cdd:COG2319 135 LASGSADGTVRLWDLATGK--------------LLRTLTGHSGAVTSVAFSPDGK---------LLASGSDDGTVRLWDL 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 162 SERKVCSQITCHEEPVMGLDF--DSQKAkgVSGSAGKVLAVWSLDDQQSLQVKKTHElinPGIAEVTLRPDHRLFATAGW 239
Cdd:COG2319 192 ATGKLLRTLTGHTGAVRSVAFspDGKLL--ASGSADGTVRLWDLATGKLLRTLTGHS---GSVRSVAFSPDGRLLASGSA 266
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 564377665 240 DHRIRVFHWRTIKPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWSL 289
Cdd:COG2319 267 DGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGkLLASGSDDGTVRLWDL 317
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
41-289 |
1.57e-27 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 110.00 E-value: 1.57e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 41 SGSQNGLVHIWSLQTRRIVATLNGHGGqGVTWLKTLPQGQQLLSQGRDPRLCLWDLAEGRNTVMDSVQLDSVgfckssil 120
Cdd:COG2319 53 AGAGDLTLLLLDAAAGALLATLLGHTA-AVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAV-------- 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 121 vrgqlcWMLAVpgkgsdetnSSLRPLLLAGYEDGSVTLWDVSERKVCSQITCHEEPVMGLDFDSQKAKGVSGSAGKVLAV 200
Cdd:COG2319 124 ------RSVAF---------SPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 201 WSLDDQQSLQVKKTHeliNPGIAEVTLRPDHRLFATAGWDHRIRVFHWRTIKPLAVLAFHSAPVHCVAFAADG-LLAAGS 279
Cdd:COG2319 189 WDLATGKLLRTLTGH---TGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGrLLASGS 265
|
250
....*....|
gi 564377665 280 KDQRISVWSL 289
Cdd:COG2319 266 ADGTVRLWDL 275
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
14-250 |
4.25e-25 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 103.45 E-value: 4.25e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 14 VLRGTQSAVNTLHFCPapgaaENPLLFSGSQNGLVHIWSLQTRRIVATLNGHGGqGVTWLKTLPQGQQLLSQGRDPRLCL 93
Cdd:COG2319 199 TLTGHTGAVRSVAFSP-----DGKLLASGSADGTVRLWDLATGKLLRTLTGHSG-SVRSVAFSPDGRLLASGSADGTVRL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 94 WDLAEGRNTVmdsvqldsvgfckssiLVRGQLCWMLAVpgkgsdetnsSLRP---LLLAGYEDGSVTLWDVSERKVCSQI 170
Cdd:COG2319 273 WDLATGELLR----------------TLTGHSGGVNSV----------AFSPdgkLLASGSDDGTVRLWDLATGKLLRTL 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 171 TCHEEPVMGLDFDSQKAKGVSGSAGKVLAVWSLDDQQSLQVKKTHElinPGIAEVTLRPDHRLFATAGWDHRIRVFHWRT 250
Cdd:COG2319 327 TGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHT---GAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
141-289 |
3.14e-21 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 90.86 E-value: 3.14e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 141 SSLRPLLLAGYEDGSVTLWDVSERKVCSQITCHEEPVMGLDFDSQKAKGVSGSAGKVLAVWSLDDQQSLQVKKTHElinP 220
Cdd:cd00200 18 SPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHT---S 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 221 GIAEVTLRPDHRLFATAGWDHRIRVFHWRTIKPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWSL 289
Cdd:cd00200 95 YVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGtFVASSSQDGTIKLWDL 164
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
141-289 |
3.41e-19 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 86.89 E-value: 3.41e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 141 SSLRPLLLAGYEDGSVTLWDVSERKVCSQITCHEEPVMGLDFDSQKAKGVSGSAGKVLAVWSLDDQQSLQVKKTHElinP 220
Cdd:COG2319 45 SPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHT---G 121
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 221 GIAEVTLRPDHRLFATAGWDHRIRVFHWRTIKPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWSL 289
Cdd:COG2319 122 AVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGkLLASGSDDGTVRLWDL 191
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
169-289 |
6.68e-17 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 78.92 E-value: 6.68e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 169 QITCHEEPVMGLDFDSQKAKGVSGSAGKVLAVWSLDDQQSLQVKKTHELinpGIAEVTLRPDHRLFATAGWDHRIRVFHW 248
Cdd:cd00200 4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTG---PVRDVAASADGTYLASGSSDKTIRLWDL 80
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 564377665 249 RTIKPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWSL 289
Cdd:cd00200 81 ETGECVRTLTGHTSYVSSVAFSPDGrILSSSSRDKTIKVWDV 122
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
125-289 |
2.25e-08 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 55.09 E-value: 2.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 125 LCWmlavpgkgsdetNSSLRPLLLAGYEDGSVTLWDVSERKVCSQITCHEEPVMGLDFDSQKAKGV-SGSAGKVLAVWSL 203
Cdd:PLN00181 538 ICW------------NSYIKSQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSADPTLLaSGSDDGSVKLWSI 605
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 204 DDQQSLQVKKTheliNPGIAEVTLRPDH-RLFATAGWDHRIRVFHWRTIK-PLAVLAFHSAPVHCVAFAADGLLAAGSKD 281
Cdd:PLN00181 606 NQGVSIGTIKT----KANICCVQFPSESgRSLAFGSADHKVYYYDLRNPKlPLCTMIGHSKTVSYVRFVDSSTLVSSSTD 681
|
....*...
gi 564377665 282 QRISVWSL 289
Cdd:PLN00181 682 NTLKLWDL 689
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
250-288 |
1.57e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 41.14 E-value: 1.57e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 564377665 250 TIKPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWS 288
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGkYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
252-288 |
9.43e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 38.87 E-value: 9.43e-05
10 20 30
....*....|....*....|....*....|....*...
gi 564377665 252 KPLAVLAFHSAPVHCVAFAADG-LLAAGSKDQRISVWS 288
Cdd:pfam00400 2 KLLKTLEGHTGSVTSLAFSPDGkLLASGSDDGTVKVWD 39
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
190-286 |
1.54e-04 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 42.37 E-value: 1.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 190 VSGSAGKVLAVWsldDQQSLQVKKTHELiNPGIAEVTLRPD-HRLFATAGWDHRIRVFHWRTIKPLAVLAFHSAPvHCVA 268
Cdd:COG3391 84 VANSGSGRVSVI---DLATGKVVATIPV-GGGPRGLAVDPDgGRLYVADSGNGRVSVIDTATGKVVATIPVGAGP-HGIA 158
|
90 100
....*....|....*....|
gi 564377665 269 FAADG--LLAAGSKDQRISV 286
Cdd:COG3391 159 VDPDGkrLYVANSGSNTVSV 178
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
104-185 |
3.68e-03 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 36.10 E-value: 3.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 104 MDsvqLDSVGFCKSSILVR---GQLCWMLAVPGKGSDETNSSLRP---LLLAGYEDGSVTLWDVSERKVCSQITCHEEPV 177
Cdd:pfam12894 7 MD---LIALATEDGELLLHrlnWQRVWTLSPDKEDLEVTSLAWRPdgkLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLI 83
|
....*...
gi 564377665 178 MGLDFDSQ 185
Cdd:pfam12894 84 TCLGWGEN 91
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
190-286 |
6.15e-03 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 37.37 E-value: 6.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564377665 190 VSGSAGKVLAVWSLDDQQSLQVKKTHELINPGIAEVTLRPDHRLFATAGWDHRIRVFHWRTIKPLAVLAFHSAPVHcVAF 269
Cdd:COG3391 39 AASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSGSGRVSVIDLATGKVVATIPVGGGPRG-LAV 117
|
90
....*....|....*....
gi 564377665 270 AADG--LLAAGSKDQRISV 286
Cdd:COG3391 118 DPDGgrLYVADSGNGRVSV 136
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
260-292 |
6.92e-03 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 37.31 E-value: 6.92e-03
10 20 30
....*....|....*....|....*....|....
gi 564377665 260 HSAPVHCVAFAADG-LLAAGSKDQRISVWSLYPC 292
Cdd:cd00200 8 HTGGVTCVAFSPDGkLLATGSGDGTIKVWDLETG 41
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