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Conserved domains on  [gi|568912922|ref|XP_006497735|]
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WD repeat-containing protein 5 isoform X1 [Mus musculus]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
36-330 4.19e-113

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 333.80  E-value: 4.19e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  36 ALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWD 115
Cdd:COG2319  111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWD 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 116 VSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 195
Cdd:COG2319  191 LATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTV 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 196 RIWDTASGQCLKTLiDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIfaNFSvTGGKWIV 275
Cdd:COG2319  271 RLWDLATGELLRTL-TGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV--AFS-PDGKTLA 346

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 568912922 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAAleNDKTIKLW 330
Cdd:COG2319  347 SGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGS--ADGTVRLW 399
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
36-330 4.19e-113

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 333.80  E-value: 4.19e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  36 ALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWD 115
Cdd:COG2319  111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWD 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 116 VSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 195
Cdd:COG2319  191 LATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTV 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 196 RIWDTASGQCLKTLiDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIfaNFSvTGGKWIV 275
Cdd:COG2319  271 RLWDLATGELLRTL-TGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV--AFS-PDGKTLA 346

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 568912922 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAAleNDKTIKLW 330
Cdd:COG2319  347 SGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGS--ADGTVRLW 399
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 37-331 1.66e-106

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 312.73  E-value: 1.66e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 116
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 117 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 196
Cdd:cd00200   81 ETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 197 IWDTASGQCLKTLIDDDNpPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNekYCIFANFSvTGGKWIVS 276
Cdd:cd00200  161 LWDLRTGKCVATLTGHTG-EVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHEN--GVNSVAFS-PDGYLLAS 236

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 568912922 277 GSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALenDKTIKLWK 331
Cdd:cd00200  237 GSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSA--DGTIRIWD 289
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 41-287 9.36e-19

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 87.06  E-value: 9.36e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGA----YDGK---FEKTISGHKLGISDVAWSSDSNLLVSASD-DKTLK 112
Cdd:PLN00181 479 LLNSSNLVCAIGFDRDGEFFATAGVNKKIKIFECesiiKDGRdihYPVVELASRSKLSGICWNSYIKSQVASSNfEGVVQ 558

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 113 IWDVSSGKCLKTLKGHSNYVFCCNFNPQS-NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDpVSAVHFNRD-GSLIVSSS 190
Cdd:PLN00181 559 VWDVARSQLVTEMKEHEKRVWSIDYSSADpTLLASGSDDGSVKLWSINQGVSIGTIKTKAN-ICCVQFPSEsGRSLAFGS 637

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 191 YDGLCRIWDTASGQC-LKTLIDDdNPPVSFVKFSPNGKYILAATlDNTLKLWDYSKGKC------LKTYTGHKNEKYciF 263
Cdd:PLN00181 638 ADHKVYYYDLRNPKLpLCTMIGH-SKTVSYVRFVDSSTLVSSST-DNTLKLWDLSMSISginetpLHSFMGHTNVKN--F 713

                        250       260
                 ....*....|....*....|....
gi 568912922 264 ANFSVTGGkWIVSGSEDNLVYIWN 287
Cdd:PLN00181 714 VGLSVSDG-YIATGSETNEVFVYH 736
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 118-157 2.47e-10

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 55.01  E-value: 2.47e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 568912922   118 SGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 157
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
119-157 2.37e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 52.35  E-value: 2.37e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 568912922  119 GKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 157
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 103-229 4.38e-03

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 38.48  E-value: 4.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  103 VSASDDKTLKIWDVSSGKCLKTLK------GhsnyvfcCNFNPQSNLI-VSGSFDESVRIWDVKTGKCLKTLPAHSDP-V 174
Cdd:TIGR03866  15 VSNEKDNTISVIDTATLKVTRTFPvgqrprG-------ITFSKDGKLLyVCASDSDTIQVIDPATGEVLHTLPSGPDPeQ 87

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568912922  175 SAVHFNrDGSLIVSSSYDGLCRIWDTASGQCLKTLidddnpPVSF----VKFSPNGKYI 229
Cdd:TIGR03866  88 FALHPN-GKILYIANEDDALVTVIDIETRKVLAQI------DVGVepegMAVSPDGKIV 139
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
36-330 4.19e-113

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 333.80  E-value: 4.19e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  36 ALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWD 115
Cdd:COG2319  111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWD 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 116 VSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 195
Cdd:COG2319  191 LATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTV 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 196 RIWDTASGQCLKTLiDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIfaNFSvTGGKWIV 275
Cdd:COG2319  271 RLWDLATGELLRTL-TGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV--AFS-PDGKTLA 346

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 568912922 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAAleNDKTIKLW 330
Cdd:COG2319  347 SGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGS--ADGTVRLW 399
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 37-331 1.66e-106

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 312.73  E-value: 1.66e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 116
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 117 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 196
Cdd:cd00200   81 ETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 197 IWDTASGQCLKTLIDDDNpPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNekYCIFANFSvTGGKWIVS 276
Cdd:cd00200  161 LWDLRTGKCVATLTGHTG-EVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHEN--GVNSVAFS-PDGYLLAS 236

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 568912922 277 GSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALenDKTIKLWK 331
Cdd:cd00200  237 GSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSA--DGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
36-330 8.41e-101

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 302.60  E-value: 8.41e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  36 ALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWD 115
Cdd:COG2319   69 ALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWD 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 116 VSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLC 195
Cdd:COG2319  149 LATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV 228

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 196 RIWDTASGQCLKTLiDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIfaNFSvTGGKWIV 275
Cdd:COG2319  229 RLWDLATGKLLRTL-TGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSV--AFS-PDGKLLA 304

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 568912922 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAAleNDKTIKLW 330
Cdd:COG2319  305 SGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGS--DDGTVRLW 357
WD40 COG2319
WD40 repeat [General function prediction only];
12-330 5.09e-87

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 267.16  E-value: 5.09e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  12 AARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGIS 91
Cdd:COG2319    3 SADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  92 DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHS 171
Cdd:COG2319   83 SVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 172 DPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNpPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKT 251
Cdd:COG2319  163 GAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTG-AVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRT 241

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568912922 252 YTGHKNEKYCIfaNFSvTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAAleNDKTIKLW 330
Cdd:COG2319  242 LTGHSGSVRSV--AFS-PDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGS--DDGTVRLW 315
WD40 COG2319
WD40 repeat [General function prediction only];
40-242 1.27e-76

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 240.58  E-value: 1.27e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSG 119
Cdd:COG2319  199 TLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATG 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 120 KCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 199
Cdd:COG2319  279 ELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWD 358

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 568912922 200 TASGQCLKTLIDDDNPpVSFVKFSPNGKYILAATLDNTLKLWD 242
Cdd:COG2319  359 LATGELLRTLTGHTGA-VTSVAFSPDGRTLASGSADGTVRLWD 400
WD40 COG2319
WD40 repeat [General function prediction only];
53-330 3.20e-69

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 221.32  E-value: 3.20e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  53 FSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYV 132
Cdd:COG2319    2 LSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 133 FCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD 212
Cdd:COG2319   82 LSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGH 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 213 DNPPVSfVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIfaNFSvTGGKWIVSGSEDNLVYIWNLQTKE 292
Cdd:COG2319  162 SGAVTS-VAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV--AFS-PDGKLLASGSADGTVRLWDLATGK 237

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 568912922 293 IVQKLQGHTDVVISTACHPTENIIASAAleNDKTIKLW 330
Cdd:COG2319  238 LLRTLTGHSGSVRSVAFSPDGRLLASGS--ADGTVRLW 273
WD40 COG2319
WD40 repeat [General function prediction only];
37-202 4.90e-61

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 200.14  E-value: 4.90e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 116
Cdd:COG2319  238 LLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDL 317

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 117 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 196
Cdd:COG2319  318 ATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVR 397


                 ....*.
gi 568912922 197 IWDTAS 202
Cdd:COG2319  398 LWDLAT 403
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 33-199 7.00e-56

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 183.31  E-value: 7.00e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  33 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLK 112
Cdd:cd00200  123 ETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIK 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 113 IWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYD 192
Cdd:cd00200  203 LWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSAD 282


                 ....*..
gi 568912922 193 GLCRIWD 199
Cdd:cd00200  283 GTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
94-330 9.89e-50

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 170.86  E-value: 9.89e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  94 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDP 173
Cdd:COG2319    1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 174 VSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSfVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYT 253
Cdd:COG2319   81 VLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRS-VAFSPDGKTLASGSADGTVRLWDLATGKLLRTLT 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568912922 254 GHKNEKYCIfaNFSvTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAAleNDKTIKLW 330
Cdd:COG2319  160 GHSGAVTSV--AFS-PDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGS--ADGTVRLW 231
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 41-287 9.36e-19

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 87.06  E-value: 9.36e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGA----YDGK---FEKTISGHKLGISDVAWSSDSNLLVSASD-DKTLK 112
Cdd:PLN00181 479 LLNSSNLVCAIGFDRDGEFFATAGVNKKIKIFECesiiKDGRdihYPVVELASRSKLSGICWNSYIKSQVASSNfEGVVQ 558

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 113 IWDVSSGKCLKTLKGHSNYVFCCNFNPQS-NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDpVSAVHFNRD-GSLIVSSS 190
Cdd:PLN00181 559 VWDVARSQLVTEMKEHEKRVWSIDYSSADpTLLASGSDDGSVKLWSINQGVSIGTIKTKAN-ICCVQFPSEsGRSLAFGS 637

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 191 YDGLCRIWDTASGQC-LKTLIDDdNPPVSFVKFSPNGKYILAATlDNTLKLWDYSKGKC------LKTYTGHKNEKYciF 263
Cdd:PLN00181 638 ADHKVYYYDLRNPKLpLCTMIGH-SKTVSYVRFVDSSTLVSSST-DNTLKLWDLSMSISginetpLHSFMGHTNVKN--F 713

                        250       260
                 ....*....|....*....|....
gi 568912922 264 ANFSVTGGkWIVSGSEDNLVYIWN 287
Cdd:PLN00181 714 VGLSVSDG-YIATGSETNEVFVYH 736
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 118-157 2.47e-10

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 55.01  E-value: 2.47e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 568912922   118 SGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 157
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
73-246 5.12e-10

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 58.94  E-value: 5.12e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  73 GAYDGKFEKTISGHKLGISDVAWSSDSNLL-VSASDDKTLKIWDVSSGKCLKTLK--GHSNYVFccnFNPQ-SNLIVSGS 148
Cdd:COG3391   53 GVALLAGLGLGAAAVADADGADAGADGRRLyVANSGSGRVSVIDLATGKVVATIPvgGGPRGLA---VDPDgGRLYVADS 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 149 FDESVRIWDVKTGKCLKTLPAHSDPVSAVhFNRDGS-LIVSSSYDGlcRIW------DTASGQCLKTLIDDDNPpvSFVK 221
Cdd:COG3391  130 GNGRVSVIDTATGKVVATIPVGAGPHGIA-VDPDGKrLYVANSGSN--TVSvivsviDTATGKVVATIPVGGGP--VGVA 204

                        170       180       190
                 ....*....|....*....|....*....|...
gi 568912922 222 FSPNGKYILAA--------TLDNTLKLWDYSKG 246
Cdd:COG3391  205 VSPDGRRLYVAnrgsntsnGGSNTVSVIDLATL 237
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 160-199 6.55e-10

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 53.86  E-value: 6.55e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 568912922   160 TGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 199
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
PTZ00421 PTZ00421
coronin; Provisional
 41-222 8.05e-10

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 59.91  E-value: 8.05e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  41 LAGHTKAVSSVKFSP-NGEWLASSSADKLIKIWGAYDGKFEKTIS-------GH--KLGISDVAWSSdSNLLVSASDDKT 110
Cdd:PTZ00421  71 LLGQEGPIIDVAFNPfDPQKLFTASEDGTIMGWGIPEEGLTQNISdpivhlqGHtkKVGIVSFHPSA-MNVLASAGADMV 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 111 LKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVS--AVHFNRDGSLI-- 186
Cdd:PTZ00421 150 VNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAKSqrCLWAKRKDLIItl 229

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 568912922 187 -VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKF 222
Cdd:PTZ00421 230 gCSKSQQRQIMLWDTRKMASPYSTVDLDQSSALFIPF 266
WD40 pfam00400
WD domain, G-beta repeat;
119-157 2.37e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 52.35  E-value: 2.37e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 568912922  119 GKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 157
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 76-115 2.50e-09

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 52.31  E-value: 2.50e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 568912922    76 DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWD 115
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
161-199 2.94e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 51.96  E-value: 2.94e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 568912922  161 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 199
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
77-115 7.06e-09

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 50.81  E-value: 7.06e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 568912922   77 GKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWD 115
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
37-72 2.34e-08

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 49.27  E-value: 2.34e-08
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 568912922   37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW 72
Cdd:pfam00400   3 LLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 37-72 3.69e-08

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 48.85  E-value: 3.69e-08
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 568912922    37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW 72
Cdd:smart00320   4 LLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 115-330 4.53e-08

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 54.71  E-value: 4.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 115 DVSSGKCLKTlkghSNYVFCCNFNPQSNLIVSGSFDESVRIWD----VKTGKCLKtLP----AHSDPVSAVHFNRD-GSL 185
Cdd:PLN00181 473 DLKQGDLLNS----SNLVCAIGFDRDGEFFATAGVNKKIKIFEcesiIKDGRDIH-YPvvelASRSKLSGICWNSYiKSQ 547

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 186 IVSSSYDGLCRIWDTASGQcLKTLIDDDNPPVSFVKFSPNGKYILAA-TLDNTLKLWDYSKGKCLKTYTGHKNeKYCIfa 264
Cdd:PLN00181 548 VASSNFEGVVQVWDVARSQ-LVTEMKEHEKRVWSIDYSSADPTLLASgSDDGSVKLWSINQGVSIGTIKTKAN-ICCV-- 623

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568912922 265 NFSVTGGKWIVSGSEDNLVYIWNLQTKEI-VQKLQGHTDVVISTACHPTENIIASAaleNDKTIKLW 330
Cdd:PLN00181 624 QFPSESGRSLAFGSADHKVYYYDLRNPKLpLCTMIGHSKTVSYVRFVDSSTLVSSS---TDNTLKLW 687
NBCH_WD40 pfam20426
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at ...
 76-317 1.62e-07

Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at the C-terminus of neurobeachin-like proteins.


Pssm-ID: 466575 [Multi-domain]  Cd Length: 350  Bit Score: 52.38  E-value: 1.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922   76 DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFccnfnPQSNLIVSGSfdeSVRI 155
Cdd:pfam20426 113 DGRMVQSIRQHKDVVSCVAVTSDGSILATGSYDTTVMVWEVLRGRSSEKRSRNTQTEF-----PRKDHVIAET---PFHI 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  156 wdvktgkclktLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAAtlD 235
Cdd:pfam20426 185 -----------LCGHDDIITCLYVSVELDIVISGSKDGTCIFHTLREGRYVRSIRHPSGCPLSKLVASRHGRIVLYA--D 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  236 NTLKLWDYS-KGKCLKTYT--GHKNekyCIfaNFSvTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPT 312
Cdd:pfam20426 252 DDLSLHLYSiNGKHIASSEsnGRLN---CI--ELS-SCGEFLVCAGDQGQIVVRSMNSLEVVRRYNGIGKIITSLTVTPE 325


                  ....*
gi 568912922  313 ENIIA 317
Cdd:pfam20426 326 ECFLA 330
PTZ00420 PTZ00420
coronin; Provisional
 83-162 2.41e-05

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 46.10  E-value: 2.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  83 ISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDV----SSGKCLK----TLKGHSNYVFCCNFNPQSNLIV-SGSFDES 152
Cdd:PTZ00420  70 LKGHTSSILDLQFNPcFSEILASGSEDLTIRVWEIphndESVKEIKdpqcILKGHKKKISIIDWNPMNYYIMcSSGFDSF 149

                         90
                 ....*....|
gi 568912922 153 VRIWDVKTGK 162
Cdd:PTZ00420 150 VNIWDIENEK 159
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 93-180 3.23e-05

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 41.88  E-value: 3.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922   93 VAWSSDSNLLVSASDDKTL--------KIWDVSsgkclktLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCL 164
Cdd:pfam12894   1 MSWCPTMDLIALATEDGELllhrlnwqRVWTLS-------PDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIV 73

                          90
                  ....*....|....*.
gi 568912922  165 KTLPAHSDPVSAVHFN 180
Cdd:pfam12894  74 HHFSAGSDLITCLGWG 89
PTZ00420 PTZ00420
coronin; Provisional
 125-199 4.12e-05

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 45.33  E-value: 4.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 125 LKGHSNYVFCCNFNP-QSNLIVSGSFDESVRIWD----------VKTGKCLktLPAHSDPVSAVHFNRDGSLIV-SSSYD 192
Cdd:PTZ00420  70 LKGHTSSILDLQFNPcFSEILASGSEDLTIRVWEiphndesvkeIKDPQCI--LKGHKKKISIIDWNPMNYYIMcSSGFD 147


                 ....*..
gi 568912922 193 GLCRIWD 199
Cdd:PTZ00420 148 SFVNIWD 154
CDC55 COG5170
Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms];
217-281 4.82e-05

Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms];


Pssm-ID: 227498 [Multi-domain]  Cd Length: 460  Bit Score: 45.02  E-value: 4.82e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568912922 217 VSFVKFSPNGKYILAATLdNTLKLWDYSKGK-CLKTYTGHKN---------EKYCIFANFSVT---GGKWIVSGSEDN 281
Cdd:COG5170  283 ISDFKFSDNGRYILSRDY-LTVKIWDVNMAKnPIKTIPMHCDlmdelndvyENDAIFDKFEISfsgDDKHVLSGSYSN 359
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 202-242 1.24e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 38.83  E-value: 1.24e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 568912922   202 SGQCLKTLIDDDNPpVSFVKFSPNGKYILAATLDNTLKLWD 242
Cdd:smart00320   1 SGELLKTLKGHTGP-VTSVAFSPDGKYLASGSDDGTIKLWD 40
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 137-226 1.28e-04

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 42.96  E-value: 1.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 137 FNPQSNLIVSGSFDESVRIWDVKTGKcLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRiWDTASGQcLKTLIDDDNPP 216
Cdd:COG3386   15 WDPDGRLYWVDIPGGRIHRYDPDGGA-VEVFAEPSGRPNGLAFDPDGRLLVADHGRGLVR-FDPADGE-VTVLADEYGKP 91

                         90
                 ....*....|...
gi 568912922 217 VSF---VKFSPNG 226
Cdd:COG3386   92 LNRpndGVVDPDG 104
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 70-138 1.28e-04

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 40.34  E-value: 1.28e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568912922   70 KIWGAYDGKfektisgHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFN 138
Cdd:pfam12894  28 RVWTLSPDK-------EDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWG 89
WD40 pfam00400
WD domain, G-beta repeat;
246-287 1.79e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 38.48  E-value: 1.79e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 568912922  246 GKCLKTYTGHKNEKYCIFANFSvtgGKWIVSGSEDNLVYIWN 287
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPD---GKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 290-331 1.89e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 38.45  E-value: 1.89e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 568912922   290 TKEIVQKLQGHTDVVISTACHPTENIIASAAleNDKTIKLWK 331
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGS--DDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
203-242 1.92e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 38.48  E-value: 1.92e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 568912922  203 GQCLKTLIDDDNPpVSFVKFSPNGKYILAATLDNTLKLWD 242
Cdd:pfam00400   1 GKLLKTLEGHTGS-VTSLAFSPDGKLLASGSDDGTVKVWD 39
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 101-233 3.23e-04

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 40.43  E-value: 3.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 101 LLVSASDDKTLKIW--DVSSGKcLKTLKGHSNYVFCCNFNPQSNLIV-----SGSFDesVRIWDVKTGKcLKTLPAHSDP 173
Cdd:COG0823    1 LAFTLSRDGNSDIYvvDLDGGE-PRRLTNSPGIDTSPAWSPDGRRIAftsdrGGGPQ--IYVVDADGGE-PRRLTFGGGY 76

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568912922 174 VSAVHFNRDGSLIVSSSY-DGLCRIW--DTASGQcLKTLIDDDNPPVsfvkFSPNGKYILAAT 233
Cdd:COG0823   77 NASPSWSPDGKRLAFVSRsDGRFDIYvlDLDGGA-PRRLTDGPGSPS----WSPDGRRIVFSS 134
NBCH_WD40 pfam20426
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at ...
 118-203 3.77e-04

Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at the C-terminus of neurobeachin-like proteins.


Pssm-ID: 466575 [Multi-domain]  Cd Length: 350  Bit Score: 41.98  E-value: 3.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  118 SGKCLKTLKGHSNyvfccNFnpqsnLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRI 197
Cdd:pfam20426  81 GAQCFATLQTPSE-----NF-----LISCGNWENSFQVISLNDGRMVQSIRQHKDVVSCVAVTSDGSILATGSYDTTVMV 150


                  ....*.
gi 568912922  198 WDTASG 203
Cdd:pfam20426 151 WEVLRG 156
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 245-287 5.16e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 37.29  E-value: 5.16e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 568912922   245 KGKCLKTYTGHKNEKYCIFANFSvtgGKWIVSGSEDNLVYIWN 287
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPD---GKYLASGSDDGTIKLWD 40
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 50-230 6.19e-04

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 41.56  E-value: 6.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922   50 SVKFSPNGEWLASSS-ADKLIKIW--GAYDGKFEKTISghKLGISDV---AWSSDSNLLVSASDDKTLKIWDVSSGKC-- 121
Cdd:COG4946   347 LPAWSPDGKSIAYFSdASGEYELYiaPADGSGEPKQLT--LGDLGRVfnpVWSPDGKKIAFTDNRGRLWVVDLASGKVrk 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  122 -LKTLKGHSNYVFccNFNPQSNLIV----SGSFDESVRIWDVKTGkclKTLPAhSDPVSavhfnrdgslivsssydglcr 196
Cdd:COG4946   425 vDTDGYGDGISDL--AWSPDSKWLAyskpGPNQLSQIFLYDVETG---KTVQL-TDGRY--------------------- 477

                         170       180       190
                  ....*....|....*....|....*....|....
gi 568912922  197 iwdtasgqclktliDDDNPpvsfvKFSPNGKYIL 230
Cdd:COG4946   478 --------------DDGSP-----AFSPDGKYLY 492
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 143-241 8.82e-04

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 39.27  E-value: 8.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 143 LIVSGSFDESVRIW--DVKTGKcLKTLPAHSDPVSAVHFNRDGSLIV-SSSYDGLCRIW--DTASGQclKTLIDDDNPPV 217
Cdd:COG0823    1 LAFTLSRDGNSDIYvvDLDGGE-PRRLTNSPGIDTSPAWSPDGRRIAfTSDRGGGPQIYvvDADGGE--PRRLTFGGGYN 77

                         90       100
                 ....*....|....*....|....*
gi 568912922 218 SFVKFSPNGKYIL-AATLDNTLKLW 241
Cdd:COG0823   78 ASPSWSPDGKRLAfVSRSDGRFDIY 102
COG3292 COG3292
Periplasmic ligand-binding sensor domain [Signal transduction mechanisms];
129-293 1.48e-03

Periplasmic ligand-binding sensor domain [Signal transduction mechanisms];


Pssm-ID: 442521 [Multi-domain]  Cd Length: 924  Bit Score: 40.36  E-value: 1.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 129 SNYVFCCNFNPQSNLIVS---GSFDESVRIWDVKTGKcLKTLPAHS---DPVSAVHFNRDGSLIVSSSYDGLCRiWDTAS 202
Cdd:COG3292  266 GNSVRSIAEDSDGNLWIRlwiGTYGGGLFRLDPKTGK-FKRYNPNGlpsNSVYSILEDSDGNLWIGTSGGGLYR-YDPKT 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 203 GQCLKTLIDD--DNPPVSFVKFSPNGKyILAATlDNTLKLWDYSKGKcLKTYTGHKNEK-------YCIFANFSvtGGKW 273
Cdd:COG3292  344 GKFTKFSEDNglSNNFIRSILEDSDGN-LWVGT-NGGLYRLDPKTGK-FTNFTHDPDKNglssnyiNSIFEDSD--GRLW 418

                        170       180
                 ....*....|....*....|
gi 568912922 274 IvsGSEDNLVYIWNLQTKEI 293
Cdd:COG3292  419 I--GTDGGGLYRYDPKTGKF 436
Nup160 pfam11715
Nucleoporin Nup120/160; Nup120 is conserved from fungi to plants to humans, and is homologous ...
 90-124 1.85e-03

Nucleoporin Nup120/160; Nup120 is conserved from fungi to plants to humans, and is homologous with the Nup160 of vertebrates. The nuclear core complex, or NPC, mediates macromolecular transport across the nuclear envelope. Deletion of the NUP120 gene causes clustering of NPCs at one side of the nuclear envelope, moderate nucleolar fragmentation and slower cell growth. The vertebrate NPC is estimated to contain between 30 and 60 different proteins. most of which are not known. Two important ones in creating the nucleoporin basket are Nup98 and Nup153, and Nup120, in conjunction with Nup 133, interacts with these two and itself plays a role in mRNA export. Nup160, Nup133, Nup96, and Nup107 are all targets of phosphorylation. The phosphorylation sites are clustered mainly at the N-terminal regions of these proteins, which are predicted to be natively disordered. The entire Nup107-160 sub-complex is stable throughout the cell cycle, thus it seems unlikely that phosphorylation affects interactions within the Nup107-160 sub-complex, but rather that it regulates the association of the sub-complex with the NPC and other proteins.


Pssm-ID: 432020 [Multi-domain]  Cd Length: 540  Bit Score: 39.75  E-value: 1.85e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 568912922   90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKT 124
Cdd:pfam11715 225 APAVTTVGGQNFLFTLSLDHTLRVWDLLTGKCLAT 259
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 38-98 2.25e-03

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 36.87  E-value: 2.25e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568912922   38 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSD 98
Cdd:pfam12894  31 TLSPDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWGEN 91
eIF2A pfam08662
Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation ...
 76-244 2.40e-03

Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation initiation factors.


Pssm-ID: 462552 [Multi-domain]  Cd Length: 194  Bit Score: 38.41  E-value: 2.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922   76 DGKFEKTISGHKLG-ISDVAWSSDSN--LLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFccnFNPQSNLIVSGSFDE- 151
Cdd:pfam08662  47 TGGPDCVVELDKEGpIHDVAWSPNGKefAVIYGYMPAKVSFFDLKGNVIHSFGEQPRNTIF---WSPFGRLVLLAGFGNl 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  152 --SVRIWDVKTGKCLKTlpahsdpvsAVHFNrdgslivsssydglcriwdtasgqclktlidddnppVSFVKFSPNGKYI 229
Cdd:pfam08662 124 agDIEFWDVVNKKKIAT---------AEASN------------------------------------ATLCEWSPDGRYF 158

                         170       180
                  ....*....|....*....|.
gi 568912922  230 LAATL------DNTLKLWDYS 244
Cdd:pfam08662 159 LTATTaprlrvDNGFKIWHYN 179
COG5354 COG5354
Uncharacterized protein, contains Trp-Asp (WD) repeat [General function prediction only];
208-294 2.67e-03

Uncharacterized protein, contains Trp-Asp (WD) repeat [General function prediction only];


Pssm-ID: 227657 [Multi-domain]  Cd Length: 561  Bit Score: 39.47  E-value: 2.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 208 TLIDDDNPPVSFVKFSPNGKYILAATLDNtLKLWDY-SKGKCLKTYtgHKNEKYCIFAnfsvTGGKWIVSGS-------- 278
Cdd:COG5354   26 TRFESENWPVAYVSESPLGTYLFSEHAAG-VECWGGpSKAKLVRFR--HPDVKYLDFS----PNEKYLVTWSrepiiepe 98

                         90       100
                 ....*....|....*....|...
gi 568912922 279 -------EDNLVYIWNLQTKEIV 294
Cdd:COG5354   99 ieispftSKNNVFVWDIASGMIV 121
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 93-244 4.02e-03

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 38.33  E-value: 4.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  93 VAWSSDSNLLVSASDDKTLKIWDVSSGKcLKTLKGHSNYVFCCNFNPQSNLIVsGSFDESVRIWDVKTGKcLKTLPAHSD 172
Cdd:COG3386   13 PVWDPDGRLYWVDIPGGRIHRYDPDGGA-VEVFAEPSGRPNGLAFDPDGRLLV-ADHGRGLVRFDPADGE-VTVLADEYG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922 173 PvSAVHFN-----RDGSLIVSSSYD-----GLCRIwdTASGQcLKTLIDDdnppVSF---VKFSPNGKY-ILAATLDNTL 238
Cdd:COG3386   90 K-PLNRPNdgvvdPDGRLYFTDMGEylptgALYRV--DPDGS-LRVLADG----LTFpngIAFSPDGRTlYVADTGAGRI 161


                 ....*.
gi 568912922 239 KLWDYS 244
Cdd:COG3386  162 YRFDLD 167
WD40 pfam00400
WD domain, G-beta repeat;
291-330 4.23e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 34.63  E-value: 4.23e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 568912922  291 KEIVQKLQGHTDVVISTACHPTENIIASAAleNDKTIKLW 330
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGS--DDGTVKVW 38
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 103-229 4.38e-03

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 38.48  E-value: 4.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568912922  103 VSASDDKTLKIWDVSSGKCLKTLK------GhsnyvfcCNFNPQSNLI-VSGSFDESVRIWDVKTGKCLKTLPAHSDP-V 174
Cdd:TIGR03866  15 VSNEKDNTISVIDTATLKVTRTFPvgqrprG-------ITFSKDGKLLyVCASDSDTIQVIDPATGEVLHTLPSGPDPeQ 87

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568912922  175 SAVHFNrDGSLIVSSSYDGLCRIWDTASGQCLKTLidddnpPVSF----VKFSPNGKYI 229
Cdd:TIGR03866  88 FALHPN-GKILYIANEDDALVTVIDIETRKVLAQI------DVGVepegMAVSPDGKIV 139
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 221-295 4.44e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 38.87  E-value: 4.44e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568912922  221 KFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYcIFANFSvTGGKWIV-SGSEDNL---VYIWNLQTKEIVQ 295
Cdd:COG4946   395 VWSPDGKKIAFTDNRGRLWVVDLASGKVRKVDTDGYGDGI-SDLAWS-PDSKWLAySKPGPNQlsqIFLYDVETGKTVQ 471
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 182-247 6.03e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 38.48  E-value: 6.03e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568912922  182 DGSLIVSSSYDGlcRIW--DTASGQClkTLIDDD--NPPVSFVKFSPNGKYIL-AATLDNTL---KLWDYSKGK 247
Cdd:COG4946   399 DGKKIAFTDNRG--RLWvvDLASGKV--RKVDTDgyGDGISDLAWSPDSKWLAySKPGPNQLsqiFLYDVETGK 468
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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