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Conserved domains on  [gi|568937376|ref|XP_006530475|]
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CAP-Gly domain-containing linker protein 1 isoform X5 [Mus musculus]

Protein Classification

CAP_GLY and CLIP1_ZNF domain-containing protein( domain architecture ID 13652084)

protein containing domains CAP_GLY, CCDC14, UPF0242, and CLIP1_ZNF

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 1.69e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.75  E-value: 1.69e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937376   213 VGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.34e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.34e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937376    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1036-1908 3.22e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.61  E-value: 3.22e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1036 QKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL--------LTSAKKEIEVMSEELRGLKSEKQLYAQEANA 1107
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1108 LKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQE 1187
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1188 ELlkmhmendsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQvkkltaenlvlVKDKDDVIQKLQSAYEELV 1267
Cdd:TIGR02168  338 EL--------------AELEEKLEELKEELESLEAELEELEAELEELESR-----------LEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1268 KDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENllQTNRDLQFEKDTLRQGQEKLSASLEAtlqvkqlLSTEA 1347
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELER-------LEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1348 ETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEeiktcraitdseciqllhEKESLAASERTLLAEKEELLSENRII 1427
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQE------------------NLEGFSEGVKALLKNQSGLSGILGVL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1428 TEKLSKQSEEVARLEMGLNEKITYLTSE------KEVACQKVAKLKKQQDSLLKEKSALELQ-NGDLLADRESSIKTIGD 1500
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALGGRLQAVVVEnlnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1501 LRRKYDQEAtnrRIVMQEkmkLLGNI---DALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTsmIQAKDN 1577
Cdd:TIGR02168  606 DLVKFDPKL---RKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS--ILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1578 lnaELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlilEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSE 1657
Cdd:TIGR02168  678 ---EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1658 QLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAL 1737
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1738 TERAEV---LQDNKNLLAEKREMMLRNEEALKE----KEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDK 1810
Cdd:TIGR02168  831 RRIAATerrLEDLEEQIEELSEDIESLAAEIEEleelIEELESELEALLNERASLEEALALLRSELEELSEELRELESKR 910

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1811 SKLTLKIRELETLHSFTAAQTAEDAMQIME---------QMTKEKTETLASLEDTKQTNAR-----LQNELDTLKENNLK 1876
Cdd:TIGR02168  911 SELRRELEELREKLAQLELRLEGLEVRIDNlqerlseeySLTLEEAEALENKIEDDEEEARrrlkrLENKIKELGPVNLA 990

                          890       900       910
                   ....*....|....*....|....*....|..
gi 568937376  1877 TVEELNKSKELLSVENQKMEEFKKEIETLKQA 1908
Cdd:TIGR02168  991 AIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 623-1421 9.83e-21

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 100.14  E-value: 9.83e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   623 QQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIES---LQSKQDSERSAHAKEMETMQAKLMKIIKEKeDSLE 699
Cdd:TIGR02169  173 EKALEELEE-VEENIERLDLIIDEKRQQLERLRREREKAERYqalLKEKREYEGYELLKEKEALERQKEAIERQL-ASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   700 AVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELevlqakyTEQSEVignftsqlsAVKEKLLDLDALRkANSEGKLELe 779
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-------GEEEQL---------RVKEKIGELEAEI-ASLERSIAE- 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   780 tLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQ 859
Cdd:TIGR02169  313 -KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   860 TRMQDTVNKLH-------QKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQL 932
Cdd:TIGR02169  392 EKLEKLKREINelkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   933 TKMNDELRLKERSVEELQLKLTKANENAS--------------FLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE 998
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARaseervrggraveeVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   999 LEKKMETSYNQCQDLkAKYEKASSET-----KTKHEEILQNLQKM---------LADTEDKLKAA-QEANRD--LMQDME 1061
Cdd:TIGR02169  552 VVVEDDAVAKEAIEL-LKRRKAGRATflplnKMRDERRDLSILSEdgvigfavdLVEFDPKYEPAfKYVFGDtlVVEDIE 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1062 ELKTQ-----------------------ADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSK 1118
Cdd:TIGR02169  631 AARRLmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1119 LIEVETKITLLQEDQQKLwsvnetlhLEKERVSEEKQVAEKRYQQE-HRDRESLVAEREKLLKEINAAQEELLKMHMEND 1197
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQL--------EQEEEKLKERLEELEEDLSSlEQEIENVKSELKELEARIEELEEDLHKLEEALN 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1198 SLEASKVSMQvlIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLvkdkDDVIQKLQSAYEELVKDQKALVQEI 1277
Cdd:TIGR02169  783 DLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL----EKEIQELQEQRIDLKEQIKSIEKEI 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1278 EDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLdca 1357
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL--- 933

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937376  1358 sKALRKAELDMRQLQTSNSSLTKLLEEIKTC-RAITDSECIQLLHEKE---------SLAASERTLLAEKEELL 1421
Cdd:TIGR02169  934 -SEIEDPKGEDEEIPEEELSLEDVQAELQRVeEEIRALEPVNMLAIQEyeevlkrldELKEKRAKLEEERKAIL 1006
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
354-888 1.24e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.70  E-value: 1.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  354 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALAR-DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEE 432
Cdd:COG4913   255 EPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRG 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  433 EK-RKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRimeLEKDLALRA 511
Cdd:COG4913   335 NGgDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEA---LEEALAEAE 411

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  512 QEVAELRRRLESskppgdvdmslsLLQEISALQEKLEAIHTDHQGEMTSLKEHFG----------------AREEAFQKE 575
Cdd:COG4913   412 AALRDLRRELRE------------LEAEIASLERRKSNIPARLLALRDALAEALGldeaelpfvgelievrPEEERWRGA 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  576 I-KALHT--------------ATEKLskENESLRSKLDhankenSDVIALWKSKLETAIASHQQAMEELKVSfskgigtD 640
Cdd:COG4913   480 IeRVLGGfaltllvppehyaaALRWV--NRLHLRGRLV------YERVRTGLPDPERPRLDPDSLAGKLDFK-------P 544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  641 SAEFAELKTQIERlRLDYqHEIESLQSKQDSERS------------AHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSA 708
Cdd:COG4913   545 HPFRAWLEAELGR-RFDY-VCVDSPEELRRHPRAitragqvkgngtRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAEL 622

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  709 EDQhlvemedtlnkLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQ------LSAVKEKLLDLDALRKANSEGKLELETLR 782
Cdd:COG4913   623 EEE-----------LAEAEERLEALEAELDALQERREALQRLAEYswdeidVASAEREIAELEAELERLDASSDDLAALE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  783 QQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELqtLKEKFASTSEEAVSAQTRm 862
Cdd:COG4913   692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAVERELR- 768

                         570       580
                  ....*....|....*....|....*.
gi 568937376  863 QDTVNKLHQKEEQFNVLSSELEKLRE 888
Cdd:COG4913   769 ENLEERIDALRARLNRAEEELERAMR 794
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2169-2185 1.59e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.59e-07
                           10
                   ....*....|....*..
gi 568937376  2169 RPYCEICEMFGHWATNC 2185
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
COG5022 super family cl34868
Myosin heavy chain [General function prediction only];
1751-2127 3.00e-07

Myosin heavy chain [General function prediction only];


The actual alignment was detected with superfamily member COG5022:

Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 56.24  E-value: 3.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1751 LAEKREMMLRNEEALKEKEKLEESYFILQkeiSQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAq 1830
Cdd:COG5022   805 LLGSRKEYRSYLACIIKLQKTIKREKKLR---ETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELA- 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1831 taedamqimEQMTKEKTETLASLEDTKQTNARLQNEL---------DTLKENNLKTvEELNKSKELL---SVENQKMEEF 1898
Cdd:COG5022   881 ---------ERQLQELKIDVKSISSLKLVNLELESEIielkkslssDLIENLEFKT-ELIARLKKLLnniDLEEGPSIEY 950

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1899 KK-----EIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLR------ 1967
Cdd:COG5022   951 VKlpelnKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEvaelqs 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1968 ESEFRKDADEEKASLQKSISLTSALLtekdAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL-ELKVKNLELqlk 2046
Cdd:COG5022  1031 ASKIISSESTELSILKPLQKLKGLLL----LENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLkTINVKDLEV--- 1103

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 2047 eNKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQSKK 2126
Cdd:COG5022  1104 -TNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRL 1182


                  .
gi 568937376 2127 K 2127
Cdd:COG5022  1183 Y 1183
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2129-2146 1.90e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.90e-04
                           10
                   ....*....|....*...
gi 568937376  2129 RLFCDICDCFDlHDTEDC 2146
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 1.69e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.75  E-value: 1.69e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937376   213 VGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.34e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.34e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937376    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 213-278 5.19e-28

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 108.44  E-value: 5.19e-28
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376    213 VGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPKYGLFAPVHKVT 278
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 60-125 3.52e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 3.52e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376     60 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1036-1908 3.22e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.61  E-value: 3.22e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1036 QKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL--------LTSAKKEIEVMSEELRGLKSEKQLYAQEANA 1107
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1108 LKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQE 1187
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1188 ELlkmhmendsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQvkkltaenlvlVKDKDDVIQKLQSAYEELV 1267
Cdd:TIGR02168  338 EL--------------AELEEKLEELKEELESLEAELEELEAELEELESR-----------LEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1268 KDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENllQTNRDLQFEKDTLRQGQEKLSASLEAtlqvkqlLSTEA 1347
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELER-------LEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1348 ETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEeiktcraitdseciqllhEKESLAASERTLLAEKEELLSENRII 1427
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQE------------------NLEGFSEGVKALLKNQSGLSGILGVL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1428 TEKLSKQSEEVARLEMGLNEKITYLTSE------KEVACQKVAKLKKQQDSLLKEKSALELQ-NGDLLADRESSIKTIGD 1500
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALGGRLQAVVVEnlnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1501 LRRKYDQEAtnrRIVMQEkmkLLGNI---DALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTsmIQAKDN 1577
Cdd:TIGR02168  606 DLVKFDPKL---RKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS--ILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1578 lnaELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlilEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSE 1657
Cdd:TIGR02168  678 ---EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1658 QLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAL 1737
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1738 TERAEV---LQDNKNLLAEKREMMLRNEEALKE----KEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDK 1810
Cdd:TIGR02168  831 RRIAATerrLEDLEEQIEELSEDIESLAAEIEEleelIEELESELEALLNERASLEEALALLRSELEELSEELRELESKR 910

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1811 SKLTLKIRELETLHSFTAAQTAEDAMQIME---------QMTKEKTETLASLEDTKQTNAR-----LQNELDTLKENNLK 1876
Cdd:TIGR02168  911 SELRRELEELREKLAQLELRLEGLEVRIDNlqerlseeySLTLEEAEALENKIEDDEEEARrrlkrLENKIKELGPVNLA 990

                          890       900       910
                   ....*....|....*....|....*....|..
gi 568937376  1877 TVEELNKSKELLSVENQKMEEFKKEIETLKQA 1908
Cdd:TIGR02168  991 AIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 623-1421 9.83e-21

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 100.14  E-value: 9.83e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   623 QQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIES---LQSKQDSERSAHAKEMETMQAKLMKIIKEKeDSLE 699
Cdd:TIGR02169  173 EKALEELEE-VEENIERLDLIIDEKRQQLERLRREREKAERYqalLKEKREYEGYELLKEKEALERQKEAIERQL-ASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   700 AVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELevlqakyTEQSEVignftsqlsAVKEKLLDLDALRkANSEGKLELe 779
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-------GEEEQL---------RVKEKIGELEAEI-ASLERSIAE- 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   780 tLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQ 859
Cdd:TIGR02169  313 -KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   860 TRMQDTVNKLH-------QKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQL 932
Cdd:TIGR02169  392 EKLEKLKREINelkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   933 TKMNDELRLKERSVEELQLKLTKANENAS--------------FLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE 998
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARaseervrggraveeVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   999 LEKKMETSYNQCQDLkAKYEKASSET-----KTKHEEILQNLQKM---------LADTEDKLKAA-QEANRD--LMQDME 1061
Cdd:TIGR02169  552 VVVEDDAVAKEAIEL-LKRRKAGRATflplnKMRDERRDLSILSEdgvigfavdLVEFDPKYEPAfKYVFGDtlVVEDIE 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1062 ELKTQ-----------------------ADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSK 1118
Cdd:TIGR02169  631 AARRLmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1119 LIEVETKITLLQEDQQKLwsvnetlhLEKERVSEEKQVAEKRYQQE-HRDRESLVAEREKLLKEINAAQEELLKMHMEND 1197
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQL--------EQEEEKLKERLEELEEDLSSlEQEIENVKSELKELEARIEELEEDLHKLEEALN 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1198 SLEASKVSMQvlIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLvkdkDDVIQKLQSAYEELVKDQKALVQEI 1277
Cdd:TIGR02169  783 DLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL----EKEIQELQEQRIDLKEQIKSIEKEI 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1278 EDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLdca 1357
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL--- 933

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937376  1358 sKALRKAELDMRQLQTSNSSLTKLLEEIKTC-RAITDSECIQLLHEKE---------SLAASERTLLAEKEELL 1421
Cdd:TIGR02169  934 -SEIEDPKGEDEEIPEEELSLEDVQAELQRVeEEIRALEPVNMLAIQEyeevlkrldELKEKRAKLEEERKAIL 1006
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 351-921 4.24e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.99  E-value: 4.24e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDG---HDQHVLELEAKMDQLRTMVEAADREKVELL 427
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEeyeLLAELARLEQDIARLEERRRELEERLEELE 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  428 NQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDL 507
Cdd:COG1196   323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  508 ALRAQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLS 587
Cdd:COG1196   403 EELEEAEEALLERLERLE-----EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  588 KENESLRSKLDHANKENSDVIALWKSKLE---TAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHE--- 661
Cdd:COG1196   478 ALAELLEELAEAAARLLLLLEAEADYEGFlegVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEdde 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  662 -----IESLQSKQ---------DSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAE 727
Cdd:COG1196   558 vaaaaIEYLKAAKagratflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  728 IKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSkan 807
Cdd:COG1196   638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE--- 714

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  808 sitKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTrMQDTVNKLHQKEEQF---NVLS-SEL 883
Cdd:COG1196   715 ---ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE-LERELERLEREIEALgpvNLLAiEEY 790

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 568937376  884 EKLRENLTDMEAKfkekddREDqLVKAKEKLENDIAEI 921
Cdd:COG1196   791 EELEERYDFLSEQ------RED-LEEARETLEEAIEEI 821
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1041-1652 8.50e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 8.50e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1041 DTEDKLKAAQEaN----RDLMQD----MEELKTQADKAKS-LTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLE 1111
Cdd:COG1196   176 EAERKLEATEE-NlerlEDILGElerqLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1112 KGSLLSKLIEVETKITLLQEDQQKLwsvnetlHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLK 1191
Cdd:COG1196   255 LEELEAELAELEAELEELRLELEEL-------ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1192 MHMENDSLEASKVSMQVLIEELrfckDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQK 1271
Cdd:COG1196   328 LEEELEELEEELEELEEELEEA----EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1272 ALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLR 1351
Cdd:COG1196   404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1352 TQLDcASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEK- 1430
Cdd:COG1196   484 EELA-EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAa 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1431 --LSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADResSIKTIGDLRRKYDQE 1508
Cdd:COG1196   563 ieYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR--TLVAARLEAALRRAV 640

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1509 ATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELktcccE 1588
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE-----E 715

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937376 1589 KNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRL 1652
Cdd:COG1196   716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 356-894 2.67e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 75.93  E-value: 2.67e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   356 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALARDG-------HDQHVLELEAKMDQLRTMVEAADREKV 424
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   425 ELLNQLEEE---------KRKVEDLQFRVEEESItkgDLETQTKLEHARTKELEQSLLFEKTK------------ADKLQ 483
Cdd:pfam15921  342 DKIEELEKQlvlanseltEARTERDQFSQESGNL---DDQLQKLLADLHKREKELSLEKEQNKrlwdrdtgnsitIDHLR 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   484 RELEDTRVatvsEKSRIMELEKDLALRAQ------------------EVAELRRRLESSKppgdvDMSLSLLQEISALQE 545
Cdd:pfam15921  419 RELDDRNM----EVQRLEALLKAMKSECQgqmerqmaaiqgknesleKVSSLTAQLESTK-----EMLRKVVEELTAKKM 489

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   546 KLEAIHTDHQGEMTSLKEHFGAReEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIA 620
Cdd:pfam15921  490 TLESSERTVSDLTASLQEKERAI-EATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALklqmaEKDKVIEILR 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   621 SHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQhEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEA 700
Cdd:pfam15921  569 QQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ-EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRA 647

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   701 VKaRLDSAEDQHLVEMEDTLNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLsavkeklldldalrkansegKLELET 780
Cdd:pfam15921  648 VK-DIKQERDQLLNEVKTSRNELNSLS---EDYEVLKRNFRNKSEEMETTTNKL--------------------KMQLKS 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   781 LRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQT 860
Cdd:pfam15921  704 AQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVAT 783

                          570       580       590
                   ....*....|....*....|....*....|....
gi 568937376   861 RMQDTVNKLHqkeeqfnVLSSELEKLRENLTDME 894
Cdd:pfam15921  784 EKNKMAGELE-------VLRSQERRLKEKVANME 810
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1525-2110 1.02e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 73.94  E-value: 1.02e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1525 NIDALKKELQERKKENQELTSSKCDLslllkeaQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRdglnLQEECQ 1604
Cdd:PRK03918  166 NLGEVIKEIKRRIERLEKFIKRTENI-------EELIKEKEKELEEVLREINEISSELPELREELEKLEK----EVKELE 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1605 KLNEEIREIQ-QTLILEKEARAKESETSLYEN--NKLHGRVVLLEEEIQRLRVCsEQLQTENFTLTQEKTNSEQKVEEII 1681
Cdd:PRK03918  235 ELKEEIEELEkELESLEGSKRKLEEKIRELEEriEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDELREIE 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1682 KEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEV-ALTERAEVLQDN-KNLLAEKREMML 1759
Cdd:PRK03918  314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAkAKKEELERLKKRlTGLTPEKLEKEL 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1760 rnEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLEsqsenrtLRKDKSKLTLKIRELETLH--SFTAAQTAEdamq 1837
Cdd:PRK03918  394 --EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKGKCPVCGRELTEEHrkELLEEYTAE---- 460

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1838 iMEQMTKEKTETLASLEDTKQTNARLQNELDTLKE--NNLKTVEELNKSKELLSVEN-QKMEEFKKEIETLKQAAAQKSQ 1914
Cdd:PRK03918  461 -LKRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKG 539

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1915 QLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMK-KSLPSNTLRESEFR---------KDADEEKASLQK 1984
Cdd:PRK03918  540 EIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEpfyneylelKDAEKELEREEK 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1985 SISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSV--VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQ 2062
Cdd:PRK03918  620 ELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 568937376 2063 AEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGE 2110
Cdd:PRK03918  700 KEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 211-271 3.01e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 72.03  E-value: 3.01e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937376  211 LKVGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLF 271
Cdd:COG5244     4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
340-923 8.02e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 70.86  E-value: 8.02e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  340 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELaLARDGHDQHVLELEAKMDQLRTMVEAA 419
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  420 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKAD------KLQRELEDTRvat 493
Cdd:PRK03918  258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRleeeinGIEERIKELE--- 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  494 vSEKSRIMELEKdlalraqEVAELRRRLESSKPpgdvdmSLSLLQEISALQEKLEaihtdhqgemtSLKEHFGARE-EAF 572
Cdd:PRK03918  335 -EKEERLEELKK-------KLKELEKRLEELEE------RHELYEEAKAKKEELE-----------RLKKRLTGLTpEKL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  573 QKEIKALHTATEKLSKENESLRSKldhankensdvialwKSKLETAIASHQQAMEELKVsfskgigtdsaefAELKTQIE 652
Cdd:PRK03918  390 EKELEELEKAKEEIEEEISKITAR---------------IGELKKEIKELKKAIEELKK-------------AKGKCPVC 441

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  653 RLRLDYQHEIEsLQSKQDSERSAHAKEMETMQAKLMKIIKEKedsleaVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKE 732
Cdd:PRK03918  442 GRELTEEHRKE-LLEEYTAELKRIEKELKEIEEKERKLRKEL------RELEKVLKKESELIKLKELAEQLKELEEKLKK 514

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  733 --LEVLQAKYTEQSEV---IGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKAN 807
Cdd:PRK03918  515 ynLEELEKKAEEYEKLkekLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL 594

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  808 SITKELQEKELVLTGLQDSLnqvnqvkETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNV-----LSSE 882
Cdd:PRK03918  595 KELEPFYNEYLELKDAEKEL-------EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEeeyeeLREE 667

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 568937376  883 LEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMK 923
Cdd:PRK03918  668 YLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 60-121 9.22e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 67.02  E-value: 9.22e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937376   60 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRP 121
Cdd:COG5244     6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1376-2052 7.71e-10

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 64.36  E-value: 7.71e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1376 SSLTKLLEEIKTCRAITDSEciqlLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGL---NEKITYL 1452
Cdd:pfam05483   81 SKLYKEAEKIKKWKVSIEAE----LKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLikeNNATRHL 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1453 TSEKEVACQKVAKLKKQQDSLLKEKSALELqngDLLADRESSIKTIGDLRrkydQEATNRRIVMQEKMKL-LGNIDALKK 1531
Cdd:pfam05483  157 CNLLKETCARSAEKTKKYEYEREETRQVYM---DLNNNIEKMILAFEELR----VQAENARLEMHFKLKEdHEKIQHLEE 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1532 ELQER--KKENQ---------ELTSSKCDLSLLLKEAQDAKKNLEKEHT-------SMIQAKDNLNAELKTCCCEKNMLL 1593
Cdd:pfam05483  230 EYKKEinDKEKQvsllliqitEKENKMKDLTFLLEESRDKANQLEEKTKlqdenlkELIEKKDHLTKELEDIKMSLQRSM 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1594 RDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEE----EIQRLRVCSEQLQTENFTLtQE 1669
Cdd:pfam05483  310 STQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEllrtEQQRLEKNEDQLKIITMEL-QK 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1670 KTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILD-------DLRLNHEVALTERAE 1742
Cdd:pfam05483  389 KSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQarekeihDLEIQLTAIKTSEEH 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1743 VLQDNKNLLAEKREMMLRNEEALKEKEKLeesyfilQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELET 1822
Cdd:pfam05483  469 YLKEVEDLKTELEKEKLKNIELTAHCDKL-------LLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEE 541

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1823 lhsfTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEI 1902
Cdd:pfam05483  542 ----KEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEN 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1903 ETLKQAAAQKSQQLSALQEENVKLAEELGRTRdevtshQKLEEERSVLNNQlLEMKKSLPSNTLRESEFRKDADEEKASL 1982
Cdd:pfam05483  618 KALKKKGSAENKQLNAYEIKVNKLELELASAK------QKFEEIIDNYQKE-IEDKKISEEKLLEEVEKAKAIADEAVKL 690

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937376  1983 QKSISL-TSALLTEKDAELEKLRNEVTVLRGENATAKSLH-SVVQTLESDKVKLELKVKNLELQLKENKRQL 2052
Cdd:pfam05483  691 QKEIDKrCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYkNKEQEQSSAKAALEIELSNIKAELLSLKKQL 762
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
354-888 1.24e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.70  E-value: 1.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  354 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALAR-DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEE 432
Cdd:COG4913   255 EPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRG 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  433 EK-RKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRimeLEKDLALRA 511
Cdd:COG4913   335 NGgDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEA---LEEALAEAE 411

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  512 QEVAELRRRLESskppgdvdmslsLLQEISALQEKLEAIHTDHQGEMTSLKEHFG----------------AREEAFQKE 575
Cdd:COG4913   412 AALRDLRRELRE------------LEAEIASLERRKSNIPARLLALRDALAEALGldeaelpfvgelievrPEEERWRGA 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  576 I-KALHT--------------ATEKLskENESLRSKLDhankenSDVIALWKSKLETAIASHQQAMEELKVSfskgigtD 640
Cdd:COG4913   480 IeRVLGGfaltllvppehyaaALRWV--NRLHLRGRLV------YERVRTGLPDPERPRLDPDSLAGKLDFK-------P 544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  641 SAEFAELKTQIERlRLDYqHEIESLQSKQDSERS------------AHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSA 708
Cdd:COG4913   545 HPFRAWLEAELGR-RFDY-VCVDSPEELRRHPRAitragqvkgngtRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAEL 622

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  709 EDQhlvemedtlnkLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQ------LSAVKEKLLDLDALRKANSEGKLELETLR 782
Cdd:COG4913   623 EEE-----------LAEAEERLEALEAELDALQERREALQRLAEYswdeidVASAEREIAELEAELERLDASSDDLAALE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  783 QQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELqtLKEKFASTSEEAVSAQTRm 862
Cdd:COG4913   692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAVERELR- 768

                         570       580
                  ....*....|....*....|....*.
gi 568937376  863 QDTVNKLHQKEEQFNVLSSELEKLRE 888
Cdd:COG4913   769 ENLEERIDALRARLNRAEEELERAMR 794
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
337-838 1.56e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.56e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  337 ETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDqhvleleakmdqlrtmV 416
Cdd:PRK02224  241 EVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAG----------------L 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  417 EAADREKVELlnQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSE 496
Cdd:PRK02224  305 DDADAEAVEA--RREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDR 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  497 KSRIMELEKdlalraqEVAELRRRLESSkpPGDVDMSLSLLQEisaLQEKLEAIHTDHQGEMTSLKEHFGAREEAFQ--- 573
Cdd:PRK02224  383 REEIEELEE-------EIEELRERFGDA--PVDLGNAEDFLEE---LREERDELREREAELEATLRTARERVEEAEAlle 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  574 -----------KEIKALHTATEKlSKENESLRSKLDHANKENSDVialwKSKLETA-----IASHQQAMEELKVSFSKGI 637
Cdd:PRK02224  451 agkcpecgqpvEGSPHVETIEED-RERVEELEAELEDLEEEVEEV----EERLERAedlveAEDRIERLEERREDLEELI 525

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  638 GTDSAEFAELKTQIERLRldyqHEIESLQSKQDSERSAHAKEMETMQAKLMKiIKEKEDSLEAVKARLDSAEDqhlveME 717
Cdd:PRK02224  526 AERRETIEEKRERAEELR----ERAAELEAEAEEKREAAAEAEEEAEEAREE-VAELNSKLAELKERIESLER-----IR 595

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  718 DTLNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKAN--SEGKLELETLRQQLEGAEKQIKNL 795
Cdd:PRK02224  596 TLLAAIADAE---DEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEAriEEAREDKERAEEYLEQVEEKLDEL 672

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 568937376  796 ETERNAESSKANSITKELQEkelvLTGLQDSLNQVNQVKETLE 838
Cdd:PRK02224  673 REERDDLQAEIGAVENELEE----LEELRERREALENRVEALE 711
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2169-2185 1.59e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.59e-07
                           10
                   ....*....|....*..
gi 568937376  2169 RPYCEICEMFGHWATNC 2185
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1751-2127 3.00e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 56.24  E-value: 3.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1751 LAEKREMMLRNEEALKEKEKLEESYFILQkeiSQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAq 1830
Cdd:COG5022   805 LLGSRKEYRSYLACIIKLQKTIKREKKLR---ETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELA- 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1831 taedamqimEQMTKEKTETLASLEDTKQTNARLQNEL---------DTLKENNLKTvEELNKSKELL---SVENQKMEEF 1898
Cdd:COG5022   881 ---------ERQLQELKIDVKSISSLKLVNLELESEIielkkslssDLIENLEFKT-ELIARLKKLLnniDLEEGPSIEY 950

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1899 KK-----EIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLR------ 1967
Cdd:COG5022   951 VKlpelnKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEvaelqs 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1968 ESEFRKDADEEKASLQKSISLTSALLtekdAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL-ELKVKNLELqlk 2046
Cdd:COG5022  1031 ASKIISSESTELSILKPLQKLKGLLL----LENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLkTINVKDLEV--- 1103

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 2047 eNKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQSKK 2126
Cdd:COG5022  1104 -TNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRL 1182


                  .
gi 568937376 2127 K 2127
Cdd:COG5022  1183 Y 1183
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 331-718 1.22e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   331 RTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKAtshvgeieqelalardghDQHVLELEAKMD 410
Cdd:TIGR02169  651 KSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI------------------ENRLDELSQELS 712

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   411 QLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTR 490
Cdd:TIGR02169  713 DASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR 792

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   491 VATVSEKSRIMElekdlalraQEVAELRRRLEsskppgDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREE 570
Cdd:TIGR02169  793 IPEIQAELSKLE---------EEVSRIEARLR------EIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE 857

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   571 AFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALwKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKtQ 650
Cdd:TIGR02169  858 NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ-LRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS-E 935

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   651 IERLRLDYQHEIESLQSKQD--SERSAHAKEMETMQAKLMKIIKEKEDsleaVKARLDSAEDQHLVEMED 718
Cdd:TIGR02169  936 IEDPKGEDEEIPEEELSLEDvqAELQRVEEEIRALEPVNMLAIQEYEE----VLKRLDELKEKRAKLEEE 1001
PRK11281 PRK11281
mechanosensitive channel MscK;
1859-2083 2.27e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 49.91  E-value: 2.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1859 TNARLQNELDTLKENNLKTVEE------LNKSKELLsvenQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELG- 1931
Cdd:PRK11281   37 TEADVQAQLDALNKQKLLEAEDklvqqdLEQTLALL----DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDe 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1932 --RTRDEVTSHQKLEEERSVLNNQLLEMKKSLpsntlresefrKDADEEKASLQKSISLTSALLTEKDAELEKLRNEvtv 2009
Cdd:PRK11281  113 etRETLSTLSLRQLESRLAQTLDQLQNAQNDL-----------AEYNSQLVSLQTQPERAQAALYANSQRLQQIRNL--- 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376 2010 LRGENATAKSLHSvvqtleSDKVKLELKVKNLELQLKENKRQLSSSSGNTD-AQAEED---ERAQESQQMIDFLNSVI 2083
Cdd:PRK11281  179 LKGGKVGGKALRP------SQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDlLQKQRDyltARIQRLEHQLQLLQEAI 250
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2129-2146 1.90e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.90e-04
                           10
                   ....*....|....*...
gi 568937376  2129 RLFCDICDCFDlHDTEDC 2146
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 1839-2021 2.32e-03

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 42.44  E-value: 2.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1839 MEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNkskellsvenQKMEEFKKEIETLKQAAAQKSQQLSA 1918
Cdd:pfam09787   49 LEELRQERDLLREEIQKLRGQIQQLRTELQELEAQQQEEAESSR----------EQLQELEEQLATERSARREAEAELER 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1919 LQEENVKLAEELGRTRDE-VTSHQKLEEERSVLNNQLleMKKSLPSNTLRESEFRKDADEEkaSLQKSISLTSALLTEKD 1997
Cdd:pfam09787  119 LQEELRYLEEELRRSKATlQSRIKDREAEIEKLRNQL--TSKSQSSSSQSELENRLHQLTE--TLIQKQTMLEALSTEKN 194

                          170       180
                   ....*....|....*....|....*..
gi 568937376  1998 A---ELEKLRNEVTVLRGENATAKSLH 2021
Cdd:pfam09787  195 SlvlQLERMEQQIKELQGEGSNGTSIN 221
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 381-798 4.08e-03

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 42.15  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   381 TSHVGEIEQELALARDGHDQ-HVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEeesitkgdlETQTK 459
Cdd:pfam06160   59 TKSLPDIEELLFEAEELNDKyRFKKAKKALDEIEELLDDIEEDIKQILEELDELLESEEKNREEVE---------ELKDK 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   460 LEHARTKELEQSLLFEKTkADKLQRELED-----TRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSkPPGDVDMSL 534
Cdd:pfam06160  130 YRELRKTLLANRFSYGPA-IDELEKQLAEieeefSQFEELTESGDYLEAREVLEKLEEETDALEELMEDI-PPLYEELKT 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   535 SL---LQEISALQEKLEaihtdhqgemtslKEHFGAREEAFQKEIKALHTATEKLSKENESLRskLDHANKENSDV---I 608
Cdd:pfam06160  208 ELpdqLEELKEGYREME-------------EEGYALEHLNVDKEIQQLEEQLEENLALLENLE--LDEAEEALEEIeerI 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   609 ALWKSKLETAIASHQQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERsaHAKEMETMQAKLM 688
Cdd:pfam06160  273 DQLYDLLEKEVDAKKYVEKNLPE-IEDYLEHAEEQNKELKEELERVQQSYTLNENELERVRGLEK--QLEELEKRYDEIV 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   689 KIIKEKE-------DSLEAVKARLDSAEDQHlVEMEDTLNKLQEAEIKVKE-LEVLQAK------YTEQSEVIG---NFT 751
Cdd:pfam06160  350 ERLEEKEvayselqEELEEILEQLEEIEEEQ-EEFKESLQSLRKDELEAREkLDEFKLElreikrLVEKSNLPGlpeSYL 428

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 568937376   752 SQLSAVKEKlldLDALRKANSEGKLELETLRQQLEGAEKQIKNLETE 798
Cdd:pfam06160  429 DYFFDVSDE---IEDLADELNEVPLNMDEVNRLLDEAQDDVDTLYEK 472
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 1.69e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.75  E-value: 1.69e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937376   213 VGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.34e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.34e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937376    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 213-278 5.19e-28

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 108.44  E-value: 5.19e-28
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376    213 VGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPKYGLFAPVHKVT 278
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 60-125 3.52e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 3.52e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376     60 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1036-1908 3.22e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.61  E-value: 3.22e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1036 QKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL--------LTSAKKEIEVMSEELRGLKSEKQLYAQEANA 1107
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1108 LKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQE 1187
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1188 ELlkmhmendsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQvkkltaenlvlVKDKDDVIQKLQSAYEELV 1267
Cdd:TIGR02168  338 EL--------------AELEEKLEELKEELESLEAELEELEAELEELESR-----------LEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1268 KDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENllQTNRDLQFEKDTLRQGQEKLSASLEAtlqvkqlLSTEA 1347
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELER-------LEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1348 ETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEeiktcraitdseciqllhEKESLAASERTLLAEKEELLSENRII 1427
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQE------------------NLEGFSEGVKALLKNQSGLSGILGVL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1428 TEKLSKQSEEVARLEMGLNEKITYLTSE------KEVACQKVAKLKKQQDSLLKEKSALELQ-NGDLLADRESSIKTIGD 1500
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALGGRLQAVVVEnlnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1501 LRRKYDQEAtnrRIVMQEkmkLLGNI---DALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTsmIQAKDN 1577
Cdd:TIGR02168  606 DLVKFDPKL---RKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS--ILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1578 lnaELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlilEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSE 1657
Cdd:TIGR02168  678 ---EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1658 QLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAL 1737
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1738 TERAEV---LQDNKNLLAEKREMMLRNEEALKE----KEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDK 1810
Cdd:TIGR02168  831 RRIAATerrLEDLEEQIEELSEDIESLAAEIEEleelIEELESELEALLNERASLEEALALLRSELEELSEELRELESKR 910

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1811 SKLTLKIRELETLHSFTAAQTAEDAMQIME---------QMTKEKTETLASLEDTKQTNAR-----LQNELDTLKENNLK 1876
Cdd:TIGR02168  911 SELRRELEELREKLAQLELRLEGLEVRIDNlqerlseeySLTLEEAEALENKIEDDEEEARrrlkrLENKIKELGPVNLA 990

                          890       900       910
                   ....*....|....*....|....*....|..
gi 568937376  1877 TVEELNKSKELLSVENQKMEEFKKEIETLKQA 1908
Cdd:TIGR02168  991 AIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 623-1421 9.83e-21

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 100.14  E-value: 9.83e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   623 QQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIES---LQSKQDSERSAHAKEMETMQAKLMKIIKEKeDSLE 699
Cdd:TIGR02169  173 EKALEELEE-VEENIERLDLIIDEKRQQLERLRREREKAERYqalLKEKREYEGYELLKEKEALERQKEAIERQL-ASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   700 AVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELevlqakyTEQSEVignftsqlsAVKEKLLDLDALRkANSEGKLELe 779
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-------GEEEQL---------RVKEKIGELEAEI-ASLERSIAE- 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   780 tLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQ 859
Cdd:TIGR02169  313 -KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   860 TRMQDTVNKLH-------QKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQL 932
Cdd:TIGR02169  392 EKLEKLKREINelkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   933 TKMNDELRLKERSVEELQLKLTKANENAS--------------FLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE 998
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARaseervrggraveeVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   999 LEKKMETSYNQCQDLkAKYEKASSET-----KTKHEEILQNLQKM---------LADTEDKLKAA-QEANRD--LMQDME 1061
Cdd:TIGR02169  552 VVVEDDAVAKEAIEL-LKRRKAGRATflplnKMRDERRDLSILSEdgvigfavdLVEFDPKYEPAfKYVFGDtlVVEDIE 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1062 ELKTQ-----------------------ADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSK 1118
Cdd:TIGR02169  631 AARRLmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1119 LIEVETKITLLQEDQQKLwsvnetlhLEKERVSEEKQVAEKRYQQE-HRDRESLVAEREKLLKEINAAQEELLKMHMEND 1197
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQL--------EQEEEKLKERLEELEEDLSSlEQEIENVKSELKELEARIEELEEDLHKLEEALN 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1198 SLEASKVSMQvlIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLvkdkDDVIQKLQSAYEELVKDQKALVQEI 1277
Cdd:TIGR02169  783 DLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL----EKEIQELQEQRIDLKEQIKSIEKEI 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1278 EDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLdca 1357
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL--- 933

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937376  1358 sKALRKAELDMRQLQTSNSSLTKLLEEIKTC-RAITDSECIQLLHEKE---------SLAASERTLLAEKEELL 1421
Cdd:TIGR02169  934 -SEIEDPKGEDEEIPEEELSLEDVQAELQRVeEEIRALEPVNMLAIQEyeevlkrldELKEKRAKLEEERKAIL 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 713-1476 7.29e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 7.29e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   713 LVEMEDTLNKLQEAeikVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKanSEGKLELETLRQQLEGAEKQI 792
Cdd:TIGR02168  181 LERTRENLDRLEDI---LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRL--EELREELEELQEELKEAEEEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   793 KNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQK 872
Cdd:TIGR02168  256 EELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   873 EEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLK 952
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   953 LTKANENASFLQKSIGEVTLKAEQSQ----QQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSEtKTKH 1028
Cdd:TIGR02168  416 RERLQQEIEELLKKLEEAELKELQAEleelEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR-LDSL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1029 EEILQNLQ------KMLADTEDKLKAAQEANRDLMQDMEELKTQADKA--KSLTYLLT----SAKKEIEVMSEELRG--- 1093
Cdd:TIGR02168  495 ERLQENLEgfsegvKALLKNQSGLSGILGVLSELISVDEGYEAAIEAAlgGRLQAVVVenlnAAKKAIAFLKQNELGrvt 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1094 -----LKSEKQLYAQEANALKLEKG--SLLSKLIEVETKITLLQED-------QQKLWSVNETLHLEKER---VSEEKQV 1156
Cdd:TIGR02168  575 flpldSIKGTEIQGNDREILKNIEGflGVAKDLVKFDPKLRKALSYllggvlvVDDLDNALELAKKLRPGyriVTLDGDL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1157 AEKRY--QQEHRDRESLV----AEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAE 1230
Cdd:TIGR02168  655 VRPGGviTGGSAKTNSSIlerrREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1231 KEHLEGQVKKLTAEnlvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQ 1310
Cdd:TIGR02168  735 LARLEAEVEQLEER-----------IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1311 TNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRA 1390
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1391 ITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQ 1470
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKI 963


                   ....*.
gi 568937376  1471 DSLLKE 1476
Cdd:TIGR02168  964 EDDEEE 969
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 778-1566 8.87e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 8.87e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   778 LETLRQQLEGAEKQIKNLETERNAESS----KANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSE 853
Cdd:TIGR02168  202 LKSLERQAEKAERYKELKAELRELELAllvlRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   854 EAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLT 933
Cdd:TIGR02168  282 EIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   934 KMNDELRLKERSVEELQLKLTKANENASFLQKsigEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDL 1013
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1014 KAKYEkassetktKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLtsakkeiEVMSEELRG 1093
Cdd:TIGR02168  439 QAELE--------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-------ERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1094 LKSEKQLYAQEANALKLEKGsLLSKLIEVETKI-----TLLQEDQQKLWSVNETL------HLEKERVSE---------- 1152
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILG-VLSELISVDEGYeaaieAALGGRLQAVVVENLNAakkaiaFLKQNELGRvtflpldsik 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1153 --EKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELL-KMHMENDSLEASKVSMQVLIEELRFCKD----------- 1218
Cdd:TIGR02168  583 gtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLgGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvrpggvit 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1219 -----KLMAMSEKaRAEKEHLEGQVKKLTAEnlvlVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMS 1293
Cdd:TIGR02168  663 ggsakTNSSILER-RREIEELEEKIEELEEK----IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1294 LDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQT 1373
Cdd:TIGR02168  738 LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1374 SNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTL---LAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKIT 1450
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLaaeIEELEELIEELESELEALLNERASLEEALALLRSELE 897

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1451 YLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDL--------------RRKYDQEATNRRIVM 1516
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltleeaealenkIEDDEEEARRRLKRL 977

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568937376  1517 QEKMKLLG--NIDALkKELQERKKENQELTSSKCDLslllkeaQDAKKNLEK 1566
Cdd:TIGR02168  978 ENKIKELGpvNLAAI-EEYEELKERYDFLTAQKEDL-------TEAKETLEE 1021
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 351-921 4.24e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.99  E-value: 4.24e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDG---HDQHVLELEAKMDQLRTMVEAADREKVELL 427
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEeyeLLAELARLEQDIARLEERRRELEERLEELE 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  428 NQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDL 507
Cdd:COG1196   323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  508 ALRAQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLS 587
Cdd:COG1196   403 EELEEAEEALLERLERLE-----EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  588 KENESLRSKLDHANKENSDVIALWKSKLE---TAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHE--- 661
Cdd:COG1196   478 ALAELLEELAEAAARLLLLLEAEADYEGFlegVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEdde 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  662 -----IESLQSKQ---------DSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAE 727
Cdd:COG1196   558 vaaaaIEYLKAAKagratflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  728 IKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSkan 807
Cdd:COG1196   638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE--- 714

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  808 sitKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTrMQDTVNKLHQKEEQF---NVLS-SEL 883
Cdd:COG1196   715 ---ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE-LERELERLEREIEALgpvNLLAiEEY 790

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 568937376  884 EKLRENLTDMEAKfkekddREDqLVKAKEKLENDIAEI 921
Cdd:COG1196   791 EELEERYDFLSEQ------RED-LEEARETLEEAIEEI 821
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 351-1188 5.48e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 5.48e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLE---LEAKMDQLRTMVEAADREKVELL 427
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEisrLEQQKQILRERLANLERQLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   428 NQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEdtrvatvSEKSRIMELEKDL 507
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE-------TLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   508 ALRAQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKL-EAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKL 586
Cdd:TIGR02168  396 ASLNNEIERLEARLERLE-----DRRERLQQEIEELLKKLeEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   587 SKENESLRSKLDHANKENSDVIALwkskletaiashqQAMEELKVSFSKGIgtdsaefAELKTQIERLRLDYQHEIESLQ 666
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSL-------------ERLQENLEGFSEGV-------KALLKNQSGLSGILGVLSELIS 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   667 SKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVK---------ARLDSAEDQHLVEmeDTLNKLQEAEIKVKELEVLQ 737
Cdd:TIGR02168  531 VDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKqnelgrvtfLPLDSIKGTEIQG--NDREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   738 AKYTEQSEVIGNFTSQLSAVKekllDLD-ALRKANSEGKLEL-------------------ETLRQQLEGAEKQIKNLET 797
Cdd:TIGR02168  609 KFDPKLRKALSYLLGGVLVVD----DLDnALELAKKLRPGYRivtldgdlvrpggvitggsAKTNSSILERRREIEELEE 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   798 ERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFN 877
Cdd:TIGR02168  685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIE 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   878 VLSSELEKLRENLTDMEAKfkekddredqlvkaKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKAN 957
Cdd:TIGR02168  765 ELEERLEEAEEELAEAEAE--------------IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   958 ENASFLQKSIGEVTLKAEQSQQQAARkheeekkeleeklleLEKKMETSYNQCQDLKAKYEKASSEtKTKHEEILQNLQK 1037
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIES---------------LAAEIEELEELIEELESELEALLNE-RASLEEALALLRS 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1038 MLADTEDKLKAAQEANRDLMQDMEELKTQADKAKsltylltSAKKEIEVMSEELRG-LKSEKQLYAQEANALKLEKGSLL 1116
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLE-------LRLEGLEVRIDNLQErLSEEYSLTLEEAEALENKIEDDE 967

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937376  1117 SKLievETKITLLQEDQQKLWSVNETlhlekerVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEE 1188
Cdd:TIGR02168  968 EEA---RRRLKRLENKIKELGPVNLA-------AIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 641-1311 3.02e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 3.02e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   641 SAEFAELKTQIERLRLdYQHEIESLQSKQDSERSAHAKEMETMQAKLMkIIKEKEDSLEAVKARLDSAEDQHLVEMEDTL 720
Cdd:TIGR02168  259 TAELQELEEKLEELRL-EVSELEEEIEELQKELYALANEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELA 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   721 NKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDA----LRKANSEGKLELETLRQQLEGAEKQIKNLE 796
Cdd:TIGR02168  337 EELAELE---EKLEELKEELESLEAELEELEAELEELESRLEELEEqletLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   797 TERNAESSKANSITKELQEKELVLtgLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQF 876
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   877 NVLSSELEKLRENLTDMEAKFKEKDDRED------QLVKAKEK----LENDIAEIMKMSGDNSSQLTKMNDELRLKERSV 946
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGilgvlsELISVDEGyeaaIEAALGGRLQAVVVENLNAAKKAIAFLKQNELG 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   947 EELQLKLTKANENAsfLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE-LEKKMETSYNQCQDLKAKY-------- 1017
Cdd:TIGR02168  572 RVTFLPLDSIKGTE--IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlGGVLVVDDLDNALELAKKLrpgyrivt 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1018 -----------------EKASSETKTKHE-EILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAK-------- 1071
Cdd:TIGR02168  650 ldgdlvrpggvitggsaKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELeelsrqis 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1072 SLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVS 1151
Cdd:TIGR02168  730 ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR 809

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1152 EEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELrfckdklmamsekaRAEK 1231
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL--------------ESEL 875

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1232 EHLEGQVKKLTAEnlvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQT 1311
Cdd:TIGR02168  876 EALLNERASLEEA-----------LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 698-1280 1.95e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.95e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  698 LEAVKARLDSAEDqHLVEMEDTLNKLQ-EAEIKVK------ELEVLQAKYteqsevignftsQLSAVKEKLLDLDALRKA 770
Cdd:COG1196   181 LEATEENLERLED-ILGELERQLEPLErQAEKAERyrelkeELKELEAEL------------LLLKLRELEAELEELEAE 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  771 NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANS-------ITKELQEKELVLTGLQDSLNQVNQVKETLEKELQT 843
Cdd:COG1196   248 LEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyeLLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  844 LKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMK 923
Cdd:COG1196   328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  924 MSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQ--SQQQAARKHEEEKKELEEKLLELEK 1001
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAllELLAELLEEAALLEAALAELLEELA 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1002 KMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQ----KMLADTEDKLKAAQEA------NRDLMQDMEELKTQADKAK 1071
Cdd:COG1196   488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavAVLIGVEAAYEAALEAalaaalQNIVVEDDEVAAAAIEYLK 567

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1072 SLT------YLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHL 1145
Cdd:COG1196   568 AAKagratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1146 EKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRfckDKLMAMSE 1225
Cdd:COG1196   648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER---LEEELEEE 724

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 568937376 1226 KARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDL 1280
Cdd:COG1196   725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1041-1652 8.50e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 8.50e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1041 DTEDKLKAAQEaN----RDLMQD----MEELKTQADKAKS-LTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLE 1111
Cdd:COG1196   176 EAERKLEATEE-NlerlEDILGElerqLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1112 KGSLLSKLIEVETKITLLQEDQQKLwsvnetlHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLK 1191
Cdd:COG1196   255 LEELEAELAELEAELEELRLELEEL-------ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1192 MHMENDSLEASKVSMQVLIEELrfckDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQK 1271
Cdd:COG1196   328 LEEELEELEEELEELEEELEEA----EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1272 ALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLR 1351
Cdd:COG1196   404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1352 TQLDcASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEK- 1430
Cdd:COG1196   484 EELA-EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAa 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1431 --LSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADResSIKTIGDLRRKYDQE 1508
Cdd:COG1196   563 ieYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR--TLVAARLEAALRRAV 640

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1509 ATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELktcccE 1588
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE-----E 715

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937376 1589 KNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRL 1652
Cdd:COG1196   716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 356-894 2.67e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 75.93  E-value: 2.67e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   356 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALARDG-------HDQHVLELEAKMDQLRTMVEAADREKV 424
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   425 ELLNQLEEE---------KRKVEDLQFRVEEESItkgDLETQTKLEHARTKELEQSLLFEKTK------------ADKLQ 483
Cdd:pfam15921  342 DKIEELEKQlvlanseltEARTERDQFSQESGNL---DDQLQKLLADLHKREKELSLEKEQNKrlwdrdtgnsitIDHLR 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   484 RELEDTRVatvsEKSRIMELEKDLALRAQ------------------EVAELRRRLESSKppgdvDMSLSLLQEISALQE 545
Cdd:pfam15921  419 RELDDRNM----EVQRLEALLKAMKSECQgqmerqmaaiqgknesleKVSSLTAQLESTK-----EMLRKVVEELTAKKM 489

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   546 KLEAIHTDHQGEMTSLKEHFGAReEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIA 620
Cdd:pfam15921  490 TLESSERTVSDLTASLQEKERAI-EATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALklqmaEKDKVIEILR 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   621 SHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQhEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEA 700
Cdd:pfam15921  569 QQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ-EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRA 647

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   701 VKaRLDSAEDQHLVEMEDTLNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLsavkeklldldalrkansegKLELET 780
Cdd:pfam15921  648 VK-DIKQERDQLLNEVKTSRNELNSLS---EDYEVLKRNFRNKSEEMETTTNKL--------------------KMQLKS 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   781 LRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQT 860
Cdd:pfam15921  704 AQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVAT 783

                          570       580       590
                   ....*....|....*....|....*....|....
gi 568937376   861 RMQDTVNKLHqkeeqfnVLSSELEKLRENLTDME 894
Cdd:pfam15921  784 EKNKMAGELE-------VLRSQERRLKEKVANME 810
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1277-1908 3.49e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 3.49e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1277 IEDLTTEKksaaEKQMSldntclTLKAERENLLQtNRDLQFEKDTLRQgqEKLSASLEATLQVKQLLSTEAETLRTQLDC 1356
Cdd:COG1196   191 LEDILGEL----ERQLE------PLERQAEKAER-YRELKEELKELEA--ELLLLKLRELEAELEELEAELEELEAELEE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1357 ASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSE 1436
Cdd:COG1196   258 LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1437 EVARLEmglnekityltSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVM 1516
Cdd:COG1196   338 ELEELE-----------EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1517 QEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTccceknmllrdg 1596
Cdd:COG1196   407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL------------ 474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1597 lnLQEECQKLNEEIREIQQTLILEKEARAKESETSlyennKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQK 1676
Cdd:COG1196   475 --LEAALAELLEELAEAAARLLLLLEAEADYEGFL-----EGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1677 VEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKRE 1756
Cdd:COG1196   548 LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1757 MMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAM 1836
Cdd:COG1196   628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937376 1837 QIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELnkskELLSVENQKMEEFKKEIETLKQA 1908
Cdd:COG1196   708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA----LEELPEPPDLEELERELERLERE 775
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 648-1353 4.10e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 75.15  E-value: 4.10e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   648 KTQIERLRLDYQHEIESLQSKQDSERSAHAKE-------METMQAKLMKIIKEKeDSLEAVKARLDSAEDQHLVEMEDTL 720
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQkfylrqsVIDLQTKLQEMQMER-DAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   721 NKLQEAE-IKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDAL--RKANSEGKLELETLRQQLEGAEKQIKNLET 797
Cdd:pfam15921  152 HELEAAKcLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEAsgKKIYEHDSMSTMHFRSLGSAISKILRELDT 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   798 ERNAESSKANSITKELQ--------EKELVLTGLQDslnQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRM----QDT 865
Cdd:pfam15921  232 EISYLKGRIFPVEDQLEalksesqnKIELLLQQHQD---RIEQLISEHEVEITGLTEKASSARSQANSIQSQLeiiqEQA 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   866 VNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEK-DDREDQLVKAKEKLENDIAE---IMKMSGDNSSQLTKMNDEL-- 939
Cdd:pfam15921  309 RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKiEELEKQLVLANSELTEARTErdqFSQESGNLDDQLQKLLADLhk 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   940 RLKERSVEELQLKLTKANENASFLqkSIGEVTLKAEQSQQQAARkheeekkeleeklleLEKKMETSYNQCQDlKAKYEK 1019
Cdd:pfam15921  389 REKELSLEKEQNKRLWDRDTGNSI--TIDHLRRELDDRNMEVQR---------------LEALLKAMKSECQG-QMERQM 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1020 ASSETKTKHEEILQNLQKMLADTEDKLKAAQEanrDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQ 1099
Cdd:pfam15921  451 AAIQGKNESLEKVSSLTAQLESTKEMLRKVVE---ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVD 527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1100 LYAQEANALKLEKGSLLSKLIEVET-KITLLQEDQqklwsVNETLHLEKERVSEekqvaekRYQQEHRDRESLVAEREKL 1178
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEAlKLQMAEKDK-----VIEILRQQIENMTQ-------LVGQHGRTAGAMQVEKAQL 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1179 LKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLM-AMSEKARAEKEhlegqVKKLTAENLVLVKDKDDVIQ 1257
Cdd:pfam15921  596 EKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVnAGSERLRAVKD-----IKQERDQLLNEVKTSRNELN 670

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1258 KLQSAYEELVKDQKALVQEIEDLTTE-KKSAAEKQMSLDNTCLTLK---------------------AERENLLQTNRDL 1315
Cdd:pfam15921  671 SLSEDYEVLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKsmegsdghamkvamgmqkqitAKRGQIDALQSKI 750

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 568937376  1316 QF----------EKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQ 1353
Cdd:pfam15921  751 QFleeamtnankEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQ 798
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 502-1296 5.00e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 5.00e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   502 ELEKDL------ALRAQEVAELRRRLEsskppgDVDMSLSLLqEISALQEKLEAIhtdhQGEMTSLKEhfgaREEAFQKE 575
Cdd:TIGR02168  197 ELERQLkslerqAEKAERYKELKAELR------ELELALLVL-RLEELREELEEL----QEELKEAEE----ELEELTAE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   576 IKALHTATEKLSKENESLRSKLDHANKENSDVIALwKSKLETAIASHQQAMEELKVSFSKGigtdSAEFAELKTQIERLR 655
Cdd:TIGR02168  262 LQELEEKLEELRLEVSELEEEIEELQKELYALANE-ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   656 LDY---QHEIESLQSKQDSERSAHAKEMETMQAkLMKIIKEKEDSLEAVKARLDSAEDQhlveMEDTLNKLQEAEIKVKE 732
Cdd:TIGR02168  337 EELaelEEKLEELKEELESLEAELEELEAELEE-LESRLEELEEQLETLRSKVAQLELQ----IASLNNEIERLEARLER 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   733 LEVLQAKYTEQSEVIGNfTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKE 812
Cdd:TIGR02168  412 LEDRRERLQQEIEELLK-KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   813 ---LQEKELVLTGLQDSLNQVNQVKETLEKELQTLKE--KFASTSEEAVSA--QTRMQD-TVNKLHQKEEQFNVLSSELE 884
Cdd:TIGR02168  491 ldsLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAAIEAalGGRLQAvVVENLNAAKKAIAFLKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   885 --------------KLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMkmsgDNSSQLTKMNDELRLkersveelq 950
Cdd:TIGR02168  571 grvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLL----GGVLVVDDLDNALEL--------- 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   951 LKLTKANENASFLQK---SIGEVTLKAEQSQQQAARKHEEEKKELEEKllelekkMETSYNQCQDLKAKYEKAssetKTK 1027
Cdd:TIGR02168  638 AKKLRPGYRIVTLDGdlvRPGGVITGGSAKTNSSILERRREIEELEEK-------IEELEEKIAELEKALAEL----RKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1028 HEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGL-------KSEKQL 1100
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAeeelaeaEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1101 YAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLK 1180
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1181 EINAAQEELlkmhmenDSLEASKVSMQVLIEELRFCKDKLMA----MSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVI 1256
Cdd:TIGR02168  867 LIEELESEL-------EALLNERASLEEALALLRSELEELSEelreLESKRSELRRELEELREKLAQLELRLEGLEVRID 939

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 568937376  1257 QKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDN 1296
Cdd:TIGR02168  940 NLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLEN 979
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1525-2110 1.02e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 73.94  E-value: 1.02e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1525 NIDALKKELQERKKENQELTSSKCDLslllkeaQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRdglnLQEECQ 1604
Cdd:PRK03918  166 NLGEVIKEIKRRIERLEKFIKRTENI-------EELIKEKEKELEEVLREINEISSELPELREELEKLEK----EVKELE 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1605 KLNEEIREIQ-QTLILEKEARAKESETSLYEN--NKLHGRVVLLEEEIQRLRVCsEQLQTENFTLTQEKTNSEQKVEEII 1681
Cdd:PRK03918  235 ELKEEIEELEkELESLEGSKRKLEEKIRELEEriEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDELREIE 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1682 KEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEV-ALTERAEVLQDN-KNLLAEKREMML 1759
Cdd:PRK03918  314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAkAKKEELERLKKRlTGLTPEKLEKEL 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1760 rnEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLEsqsenrtLRKDKSKLTLKIRELETLH--SFTAAQTAEdamq 1837
Cdd:PRK03918  394 --EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKGKCPVCGRELTEEHrkELLEEYTAE---- 460

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1838 iMEQMTKEKTETLASLEDTKQTNARLQNELDTLKE--NNLKTVEELNKSKELLSVEN-QKMEEFKKEIETLKQAAAQKSQ 1914
Cdd:PRK03918  461 -LKRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKG 539

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1915 QLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMK-KSLPSNTLRESEFR---------KDADEEKASLQK 1984
Cdd:PRK03918  540 EIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEpfyneylelKDAEKELEREEK 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1985 SISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSV--VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQ 2062
Cdd:PRK03918  620 ELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 568937376 2063 AEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGE 2110
Cdd:PRK03918  700 KEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 352-1187 1.86e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 1.86e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   352 LQEALKEKQQHIEQLLAERD--------LERAEVAKATSHVGEIEQELALARDGHDQhVLELEAKMDQLRTMVEAADREK 423
Cdd:TIGR02169  189 LDLIIDEKRQQLERLRREREkaeryqalLKEKREYEGYELLKEKEALERQKEAIERQ-LASLEEELEKLTEEISELEKRL 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   424 VELLNQLEEEKRKVEDLQfrvEEESitkgdLETQTKLE--HARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIM 501
Cdd:TIGR02169  268 EEIEQLLEELNKKIKDLG---EEEQ-----LRVKEKIGelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   502 ELEKDLALRAQEVAELRRRLESSKppgdvdmslsllQEISALQEKLEAIHTDHQgemTSLKEHFGARE--EAFQKEIKAL 579
Cdd:TIGR02169  340 ELEREIEEERKRRDKLTEEYAELK------------EELEDLRAELEEVDKEFA---ETRDELKDYREklEKLKREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   580 HTATEKLSKENESLRSKLDHANKENSDV---IALWKSKLETAIASHQQAMEELKvSFSKGIGTDSAEFAELKTQIERLrl 656
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNAAIAGIeakINELEEEKEDKALEIKKQEWKLE-QLAADLSKYEQELYDLKEEYDRV-- 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   657 dyQHEIESLQSKQDsERSAHAKEMETMQAKLMKIIKEKEDSLEAVK---ARLDSAEDQHLVEMEDTL-NKLQEAeikVKE 732
Cdd:TIGR02169  482 --EKELSKLQRELA-EAEAQARASEERVRGGRAVEEVLKASIQGVHgtvAQLGSVGERYATAIEVAAgNRLNNV---VVE 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   733 LEVLQAKYTE--QSEVIGNFTS-QLSAVKEKLLDLDALRKANSEG-KLELETLRQQLEGAEKQI-------KNLETERNA 801
Cdd:TIGR02169  556 DDAVAKEAIEllKRRKAGRATFlPLNKMRDERRDLSILSEDGVIGfAVDLVEFDPKYEPAFKYVfgdtlvvEDIEAARRL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   802 ESS-KANSITKELQEKELVLTG--------------LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTV 866
Cdd:TIGR02169  636 MGKyRMVTLEGELFEKSGAMTGgsraprggilfsrsEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   867 NKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDdredqlvkakEKLENDIAEimkmsgdnssqLTKMNDELRLKERSV 946
Cdd:TIGR02169  716 RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE----------QEIENVKSE-----------LKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   947 EELQLKLT--KANENASFLQKSIGEVT-LKAEQSQQQAARKH-EEEKKELEEKLLELEKKMETSYNQCQDLKAKyekass 1022
Cdd:TIGR02169  775 HKLEEALNdlEARLSHSRIPEIQAELSkLEEEVSRIEARLREiEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ------ 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1023 etKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKaksltylltsAKKEIEVMSEELRGLKSEKQLYA 1102
Cdd:TIGR02169  849 --IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE----------LEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1103 QEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVnETLHLEKERVSEEKQ-------VAEKRYQQEHRDRESLVAER 1175
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRalepvnmLAIQEYEEVLKRLDELKEKR 995

                          890
                   ....*....|..
gi 568937376  1176 EKLLKEINAAQE 1187
Cdd:TIGR02169  996 AKLEEERKAILE 1007
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1320-2093 2.81e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 2.81e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1320 DTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLdcaSKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQL 1399
Cdd:TIGR02169  194 DEKRQQLERLRREREKAERYQALLKEKREYEGYEL---LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1400 LHEKESLAASERTLLAEkeellsENRIITEKLSKQSEEVARLEMGLNEKitylTSEKEVACQKVAKLKKQQDSLLKEKSA 1479
Cdd:TIGR02169  271 EQLLEELNKKIKDLGEE------EQLRVKEKIGELEAEIASLERSIAEK----ERELEDAEERLAKLEAEIDKLLAEIEE 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1480 LELQNGDLLADRESSIKTIGDLRRKYD-------QEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSL 1552
Cdd:TIGR02169  341 LEREIEEERKRRDKLTEEYAELKEELEdlraeleEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1553 LLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDG-------LNLQEECQKLNEEIREIQQTLIlEKEARA 1625
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLskyeqelYDLKEEYDRVEKELSKLQRELA-EAEAQA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1626 KESETSLYENNKLhgrVVLLEEEIQRLRVCSEQL-QTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSD 1704
Cdd:TIGR02169  500 RASEERVRGGRAV---EEVLKASIQGVHGTVAQLgSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRAT 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1705 FAALSKskleLQELHSCLTKILDDLRLNHEVALTERAE--------VLQDNK--NLLAEKREMMLRNEEALKEKEKLEES 1774
Cdd:TIGR02169  577 FLPLNK----MRDERRDLSILSEDGVIGFAVDLVEFDPkyepafkyVFGDTLvvEDIEAARRLMGKYRMVTLEGELFEKS 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1775 YFIlqkeisqlaqTNSHISANLLESQSenrtlRKDKSKLTLKIRELETLHsftaaQTAEDAMQIMEQMTKEKTETLASLE 1854
Cdd:TIGR02169  653 GAM----------TGGSRAPRGGILFS-----RSEPAELQRLRERLEGLK-----RELSSLQSELRRIENRLDELSQELS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1855 DTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTR 1934
Cdd:TIGR02169  713 DASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1935 -DEVTSH-QKLEEERSVLNNQLLEMKKSLPSNTLRES----------EFRKDADEEKASLQKSISLTSALLTEKDAELEK 2002
Cdd:TIGR02169  793 iPEIQAElSKLEEEVSRIEARLREIEQKLNRLTLEKEylekeiqelqEQRIDLKEQIKSIEKEIENLNGKKEELEEELEE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  2003 LRNEVTVLRGENATAKS----LHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQQMIDF 2078
Cdd:TIGR02169  873 LEAALRDLESRLGDLKKerdeLEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS 952

                          810
                   ....*....|....*
gi 568937376  2079 LNSVIVDLQRKNQDL 2093
Cdd:TIGR02169  953 LEDVQAELQRVEEEI 967
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1082-1906 2.83e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 2.83e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1082 KEIEVMSEELRGLKSEK--QLYAQEANALKLEK-GSLLSKLIEVETKITLlqedqqklwsvNETLHLEKERVSEEKQVAE 1158
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKrqQLERLRREREKAERyQALLKEKREYEGYELL-----------KEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1159 KRYQQEHR-----DRESLVAEREKLLKEINA-----AQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKAR 1228
Cdd:TIGR02169  249 LEEELEKLteeisELEKRLEEIEQLLEELNKkikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1229 AEKEHLEGQVKKLTAENLVLVKDKDdviqKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENL 1308
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRD----KLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1309 LQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTC 1388
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1389 RAITDSECIQLLHEKESLAASERTLLAEKEELLSENR----IITEKLSKQSEEVARLEMGLNEKITYLTSEKE-VACQKV 1463
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDaVAKEAI 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1464 AKLKKQQDS----LLKEKSALELQNGDLLAdRESSIKTIGDLRRKYDQEATNRRIVMQEKMkLLGNIDALKKELQERK-- 1537
Cdd:TIGR02169  565 ELLKRRKAGratfLPLNKMRDERRDLSILS-EDGVIGFAVDLVEFDPKYEPAFKYVFGDTL-VVEDIEAARRLMGKYRmv 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1538 ---KENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTccceknmllrdglnlqeecqkLNEEIREIQ 1614
Cdd:TIGR02169  643 tleGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSS---------------------LQSELRRIE 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1615 QtLILEKEARAKESETSLYENNKlhgRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQL 1694
Cdd:TIGR02169  702 N-RLDELSQELSDASRKIGEIEK---EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1695 AANIETLK-----SDFAALSKSKLELQELHSCLTKILDDL------RLNHEVALTERAEVLQDNKNLLAEKREMMLRNEE 1763
Cdd:TIGR02169  778 EEALNDLEarlshSRIPEIQAELSKLEEEVSRIEARLREIeqklnrLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1764 ALK-EKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIME-- 1840
Cdd:TIGR02169  858 NLNgKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEie 937

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937376  1841 ---QMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEE----------LNKSKELLSVENQKMEEFKKEIETLK 1906
Cdd:TIGR02169  938 dpkGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEyeevlkrldeLKEKRAKLEEERKAILERIEEYEKKK 1016
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 211-271 3.01e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 72.03  E-value: 3.01e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937376  211 LKVGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLF 271
Cdd:COG5244     4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 714-1611 3.44e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 3.44e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   714 VEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEvignftsQLSAVKEKLLDLDALRKanSEGKLELETLRQQLEGAEKQIK 793
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLE-------RLRREREKAERYQALLK--EKREYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   794 NLETERNAESSKANSITKELQEKELVLTGLQDSLNQVN-QVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQK 872
Cdd:TIGR02169  241 AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNkKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   873 EEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEndiaeimkmsgdnssqltkmnDELRLKERSVEELQLK 952
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK---------------------EELEDLRAELEEVDKE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   953 LTKANENASFLQKSIGEVTLKAEQSQQQAARKheeekkeleekllelekkmetsynqcqdlkakyekasSETKTKHEEIL 1032
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINELKRELDRL-------------------------------------QEELQRLSEEL 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1033 QNLQKMLADTEDKLKAAQEANRDLmqdMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEK 1112
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDK---ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1113 GSLLSKLIEVETKITLLQEDQQKLW-SVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLK 1191
Cdd:TIGR02169  500 RASEERVRGGRAVEEVLKASIQGVHgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLP 579

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1192 MH-MENDSLEASKVSMQVLIE---ELRFCKDK-------------LMAMSEKARAekehLEGQVKKLTAENLVLvkDKDD 1254
Cdd:TIGR02169  580 LNkMRDERRDLSILSEDGVIGfavDLVEFDPKyepafkyvfgdtlVVEDIEAARR----LMGKYRMVTLEGELF--EKSG 653

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1255 VIQKLQSAYEELVKDQKALVQEIEDLTTEKKSaaekqmsldntcltLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLE 1334
Cdd:TIGR02169  654 AMTGGSRAPRGGILFSRSEPAELQRLRERLEG--------------LKRELSSLQSELRRIENRLDELSQELSDASRKIG 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1335 ATLQVKQLLSTEAETLRtqldcaskalRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLL 1414
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLK----------ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS 789

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1415 AEKEellsenRIITEKLSKQSEEVARLEMGLNE---KITYLTSEKEVACQKVAKLKKQQDsllkeksALELQNGDLLADR 1491
Cdd:TIGR02169  790 HSRI------PEIQAELSKLEEEVSRIEARLREieqKLNRLTLEKEYLEKEIQELQEQRI-------DLKEQIKSIEKEI 856

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1492 ESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSM 1571
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI 936

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|
gi 568937376  1572 IQAKDNLNAElktccCEKNMLLRDglnLQEECQKLNEEIR 1611
Cdd:TIGR02169  937 EDPKGEDEEI-----PEEELSLED---VQAELQRVEEEIR 968
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 406-1153 3.88e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 72.07  E-value: 3.88e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   406 EAKMDQLRTMVEAADREKVELLnqLEEEKRKVEDLQFRVEEESitkgdletqtKLEHARTKELEQSLLFEKTKADKLQRE 485
Cdd:pfam15921   58 EVELDSPRKIIAYPGKEHIERV--LEEYSHQVKDLQRRLNESN----------ELHEKQKFYLRQSVIDLQTKLQEMQME 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   486 ledtRVATVSEKSRIMELEKDLALRAQEVAElrrRLESSKppgdvDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHF 565
Cdd:pfam15921  126 ----RDAMADIRRRESQSQEDLRNQLQNTVH---ELEAAK-----CLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   566 GAREEAFQKEI-----------KALHTATEKLSKENESLRSKLdhankenSDVIALWKSKLETAIASHQQAMEELkvsfs 634
Cdd:pfam15921  194 VDFEEASGKKIyehdsmstmhfRSLGSAISKILRELDTEISYL-------KGRIFPVEDQLEALKSESQNKIELL----- 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   635 kgigtdsaeFAELKTQIERLRLDYQHEIESLQSKQDSERS---AHAKEMETMQ-------AKLMKIIKEKEDSLEAVKAR 704
Cdd:pfam15921  262 ---------LQQHQDRIEQLISEHEVEITGLTEKASSARSqanSIQSQLEIIQeqarnqnSMYMRQLSDLESTVSQLRSE 332

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   705 LDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSeviGNFTSQLSAV------KEKLLDLDA-----LRKANSE 773
Cdd:pfam15921  333 LREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQES---GNLDDQLQKLladlhkREKELSLEKeqnkrLWDRDTG 409

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   774 GKLELETLRQQLEGAEKQIKNLETERNAESSKANSitkELQEKELVLTGLQDSLNQVNQVKETLEKELQTLK---EKFAS 850
Cdd:pfam15921  410 NSITIDHLRRELDDRNMEVQRLEALLKAMKSECQG---QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRkvvEELTA 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   851 TSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLE---------NDIAEI 921
Cdd:pfam15921  487 KKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEalklqmaekDKVIEI 566

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   922 MKMSGDNSSQLT-------------KMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQ-QAARKHEE 987
Cdd:pfam15921  567 LRQQIENMTQLVgqhgrtagamqveKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLvNAGSERLR 646

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   988 EKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMladtEDKLKAAQ---EANRDLMQDMEELK 1064
Cdd:pfam15921  647 AVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKL----KMQLKSAQselEQTRNTLKSMEGSD 722

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1065 TQADK-AKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETkitllqeDQQKLWSVNETL 1143
Cdd:pfam15921  723 GHAMKvAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVAT-------EKNKMAGELEVL 795

                          810
                   ....*....|
gi 568937376  1144 HLEKERVSEE 1153
Cdd:pfam15921  796 RSQERRLKEK 805
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1348-2077 3.89e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.01  E-value: 3.89e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1348 ETLRTQLDCASKALR-KAELDMRQLQTSNSSLTKLLEEIKTCRAITDseciqllhEKESLAASERTLLAEKEELLSENRI 1426
Cdd:TIGR02168  203 KSLERQAEKAERYKElKAELRELELALLVLRLEELREELEELQEELK--------EAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1427 ITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYD 1506
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1507 ---QEATNRRIVMQEkmkLLGNIDALKKELQERKKE----NQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNL- 1578
Cdd:TIGR02168  355 sleAELEELEAELEE---LESRLEELEEQLETLRSKvaqlELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLe 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1579 NAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQ 1658
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAL 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1659 LQTEN-----FTLTQEKTNSEQKVEEIIkEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNH 1733
Cdd:TIGR02168  512 LKNQSglsgiLGVLSELISVDEGYEAAI-EAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGND 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1734 EVALTERAEVLQDNKNLLAEKREMM---------------LRNEEALKEKEKLEESYFILQKEI----SQLAQTNSHISA 1794
Cdd:TIGR02168  591 REILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvddLDNALELAKKLRPGYRIVTLDGDLvrpgGVITGGSAKTNS 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1795 NLLESQSENRTLRKDKSKLTLKIRELET-----LHSFTAAQTA-EDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELD 1868
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKalaelRKELEELEEElEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1869 TLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVtshQKLEEERS 1948
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA---ANLRERLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1949 VLNNQLLEMKKSLPsntlRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGEnatakslhsvVQTLE 2028
Cdd:TIGR02168  828 SLERRIAATERRLE----DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA----------LALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 568937376  2029 SDKVKLELKVKNLELQLKENKRQLSSSsgnTDAQAEEDERAQESQQMID 2077
Cdd:TIGR02168  894 SELEELSEELRELESKRSELRRELEEL---REKLAQLELRLEGLEVRID 939
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 768-1442 3.93e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 3.93e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  768 RKANSEGKLE--------LETLRQQLEgaeKQIKNLETERN-AEssKANSITKELQEKELVLTGLQDslnqvnqvkETLE 838
Cdd:COG1196   173 RKEEAERKLEateenlerLEDILGELE---RQLEPLERQAEkAE--RYRELKEELKELEAELLLLKL---------RELE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  839 KELQTLKEKFASTSEEAVSAQTRMQDtvnklhqkeeqfnvLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDI 918
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAE--------------LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  919 AEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLE 998
Cdd:COG1196   305 ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  999 LEKKME--TSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL 1076
Cdd:COG1196   385 AEELLEalRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1077 LTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVetKITLLQEDQQKLW-SVNETLHLEKERVSEEKQ 1155
Cdd:COG1196   465 LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV--KAALLLAGLRGLAgAVAVLIGVEAAYEAALEA 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1156 VAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRfckdklmamsekaraekehle 1235
Cdd:COG1196   543 ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV--------------------- 601

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1236 gqvkkltaenlvlvkdkdDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDL 1315
Cdd:COG1196   602 ------------------DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1316 QFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEiktcraitdse 1395
Cdd:COG1196   664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA----------- 732

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*..
gi 568937376 1396 ciqllhEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLE 1442
Cdd:COG1196   733 ------EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
340-923 8.02e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 70.86  E-value: 8.02e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  340 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELaLARDGHDQHVLELEAKMDQLRTMVEAA 419
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  420 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKAD------KLQRELEDTRvat 493
Cdd:PRK03918  258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRleeeinGIEERIKELE--- 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  494 vSEKSRIMELEKdlalraqEVAELRRRLESSKPpgdvdmSLSLLQEISALQEKLEaihtdhqgemtSLKEHFGARE-EAF 572
Cdd:PRK03918  335 -EKEERLEELKK-------KLKELEKRLEELEE------RHELYEEAKAKKEELE-----------RLKKRLTGLTpEKL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  573 QKEIKALHTATEKLSKENESLRSKldhankensdvialwKSKLETAIASHQQAMEELKVsfskgigtdsaefAELKTQIE 652
Cdd:PRK03918  390 EKELEELEKAKEEIEEEISKITAR---------------IGELKKEIKELKKAIEELKK-------------AKGKCPVC 441

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  653 RLRLDYQHEIEsLQSKQDSERSAHAKEMETMQAKLMKIIKEKedsleaVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKE 732
Cdd:PRK03918  442 GRELTEEHRKE-LLEEYTAELKRIEKELKEIEEKERKLRKEL------RELEKVLKKESELIKLKELAEQLKELEEKLKK 514

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  733 --LEVLQAKYTEQSEV---IGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKAN 807
Cdd:PRK03918  515 ynLEELEKKAEEYEKLkekLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL 594

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  808 SITKELQEKELVLTGLQDSLnqvnqvkETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNV-----LSSE 882
Cdd:PRK03918  595 KELEPFYNEYLELKDAEKEL-------EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEeeyeeLREE 667

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 568937376  883 LEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMK 923
Cdd:PRK03918  668 YLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 351-921 9.40e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 9.40e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  351 ALQEALKEKQqhIEQLLAERDLERAEVAKAtshvgeiEQELAlardghdqhvlELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:COG1196   217 ELKEELKELE--AELLLLKLRELEAELEEL-------EAELE-----------ELEAELEELEAELAELEAELEELRLEL 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  431 EEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALR 510
Cdd:COG1196   277 EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  511 AQEVAELRRRLESskppgDVDMSLSLLQEISALQEKLEAIHTDHQgEMTSLKEHFGAREEAFQKEIKALHTATEKLSKEN 590
Cdd:COG1196   357 EAELAEAEEALLE-----AEAELAEAEEELEELAEELLEALRAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEAL 430

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  591 ESLRSKLDHANKENSDvIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDyQHEIESLQSKQD 670
Cdd:COG1196   431 AELEEEEEEEEEALEE-AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL-LEAEADYEGFLE 508

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  671 SERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVK--------ELEVLQAKYTE 742
Cdd:COG1196   509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratflPLDKIRARAAL 588

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  743 QSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQ-QLEGAEKQIKNLETER----------NAESSKANSITK 811
Cdd:COG1196   589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAaRLEAALRRAVTLAGRLrevtlegeggSAGGSLTGGSRR 668

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  812 ELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKL-HQKEEQFNVLSSELEKLRENL 890
Cdd:COG1196   669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALeEQLEAEREELLEELLEEEELL 748

                         570       580       590
                  ....*....|....*....|....*....|.
gi 568937376  891 TDMEAKFKEKDDREDQLVKAKEKLENDIAEI 921
Cdd:COG1196   749 EEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 612-1183 1.08e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 1.08e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  612 KSKLETAIASHQQAMEELKvsfskgigtdsAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKlmKII 691
Cdd:COG1196   241 LEELEAELEELEAELEELE-----------AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI--ARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  692 KEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELE-VLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKA 770
Cdd:COG1196   308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEeELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  771 NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFAS 850
Cdd:COG1196   388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  851 TSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDRE-----DQLVKAKEKLENDIAEIMKMS 925
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavAVLIGVEAAYEAALEAALAAA 547

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  926 G-----DNSSQLTKMNDEL-RLKERSVEELQL---KLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKL 996
Cdd:COG1196   548 LqnivvEDDEVAAAAIEYLkAAKAGRATFLPLdkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  997 LELEKKMETSYN------------QCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELK 1064
Cdd:COG1196   628 VAARLEAALRRAvtlagrlrevtlEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1065 TQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNetlh 1144
Cdd:COG1196   708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPVN---- 783

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 568937376 1145 lekERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEIN 1183
Cdd:COG1196   784 ---LLAIEEYEELEERYDFLSEQREDLEEARETLEEAIE 819
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 914-1823 2.87e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.33  E-value: 2.87e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   914 LENDIAEIMKMSG--------------DNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSigevTLKAEQSQQ 979
Cdd:TIGR02169  140 LQGDVTDFISMSPverrkiideiagvaEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERYQA 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   980 QAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKakyekassETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQD 1059
Cdd:TIGR02169  216 LLKEKREYEGYELLKEKEALERQKEAIERQLASLE--------EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1060 mEELKTQADKAkSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSV 1139
Cdd:TIGR02169  288 -EQLRVKEKIG-ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEE 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1140 NETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASkvsmqvlIEELRFCKDK 1219
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAA-------IAGIEAKINE 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1220 LMAMSEKARAEKEHLEGQVKKLTAEnlvlVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCL 1299
Cdd:TIGR02169  439 LEEEKEDKALEIKKQEWKLEQLAAD----LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEE 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1300 TLKAERENLLQTNRDL-QFEKDTLRQGQEKLSASLEATLQVKQLLSTEAetlrTQLDCASKALRKAELDMRQLQTSNSSL 1378
Cdd:TIGR02169  515 VLKASIQGVHGTVAQLgSVGERYATAIEVAAGNRLNNVVVEDDAVAKEA----IELLKRRKAGRATFLPLNKMRDERRDL 590

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1379 TKLLEEIKTCRAITDSECIQlLHEKESLAASERTLLAEKEE----LLSENRIIT---EKLSKQSEEV--ARLEMGLNEKI 1449
Cdd:TIGR02169  591 SILSEDGVIGFAVDLVEFDP-KYEPAFKYVFGDTLVVEDIEaarrLMGKYRMVTlegELFEKSGAMTggSRAPRGGILFS 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1450 TYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDAL 1529
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1530 KKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKehtsmiqakdnlnaelktccceknMLLRDGL-NLQEECQKLNE 1608
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA------------------------RLSHSRIpEIQAELSKLEE 805

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1609 EIREIqqtlilekEARAKESETSLyenNKLHGRVVLLEEEIQrlrvcseQLQTENFTLTQEKTNSEQKVEEIIKEKELLS 1688
Cdd:TIGR02169  806 EVSRI--------EARLREIEQKL---NRLTLEKEYLEKEIQ-------ELQEQRIDLKEQIKSIEKEIENLNGKKEELE 867

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1689 AETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVA------LTERAEVLQDNKNLLAEKREMMLRNE 1762
Cdd:TIGR02169  868 EELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKrkrlseLKAKLEALEEELSEIEDPKGEDEEIP 947

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376  1763 EALKEKEKLEESYFILQKEISQLAQTN-------SHISANLLESQSENRTLRKDKSKLTLKIRELETL 1823
Cdd:TIGR02169  948 EEELSLEDVQAELQRVEEEIRALEPVNmlaiqeyEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 60-121 9.22e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 67.02  E-value: 9.22e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937376   60 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRP 121
Cdd:COG5244     6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 872-1768 1.00e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.40  E-value: 1.00e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   872 KEEQFNVLSSELEklrenltdmEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQL 951
Cdd:TIGR02169  209 KAERYQALLKEKR---------EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   952 KLTKANENASF-LQKSIGEVTLKAEQSQQQAARKheeekkeleekllelEKKMETSYNQCQDLKAKYEKASSEtKTKHEE 1030
Cdd:TIGR02169  280 KIKDLGEEEQLrVKEKIGELEAEIASLERSIAEK---------------ERELEDAEERLAKLEAEIDKLLAE-IEELER 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1031 ILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLtylLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKL 1110
Cdd:TIGR02169  344 EIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE---LKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1111 EKGSLLSKLIEVETKITLLQEdqqklwsvnetlhlEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELL 1190
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEE--------------EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1191 KMHMENDSLEASKvsmQVLIEELRFCKdklmAMSEKARAEKEHLEGQVKKL----------------TAENLVLVKDKDD 1254
Cdd:TIGR02169  487 KLQRELAEAEAQA---RASEERVRGGR----AVEEVLKASIQGVHGTVAQLgsvgeryataievaagNRLNNVVVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1255 VIQKLqsayeELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAereNLLQTnrDLQFEK-------DTLrqgqe 1327
Cdd:TIGR02169  560 AKEAI-----ELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAV---DLVEF--DPKYEPafkyvfgDTL----- 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1328 kLSASLEAT---LQVKQLLSTEAETLRTQ--LDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHE 1402
Cdd:TIGR02169  625 -VVEDIEAArrlMGKYRMVTLEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1403 KESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALEL 1482
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE----EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1483 QNGDLLAD-RESSIKTIGDLRRKydQEATNRRIVmqekmkllGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAK 1561
Cdd:TIGR02169  780 ALNDLEARlSHSRIPEIQAELSK--LEEEVSRIE--------ARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQI 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1562 KNLEKEHTSMIQAKDNLNAELKtcccEKNMLLRDglnLQEECQKLNEEIREIQQTLileKEARAKESEtslyennklhgr 1641
Cdd:TIGR02169  850 KSIEKEIENLNGKKEELEEELE----ELEAALRD---LESRLGDLKKERDELEAQL---RELERKIEE------------ 907

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1642 vvlLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKE-KELLSAEtaQLAANIETLKSDFAALSKSKLELQELHS 1720
Cdd:TIGR02169  908 ---LEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpEEELSLE--DVQAELQRVEEEIRALEPVNMLAIQEYE 982

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*...
gi 568937376  1721 CLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEK 1768
Cdd:TIGR02169  983 EVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFEAINEN 1030
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 777-1290 1.61e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 66.58  E-value: 1.61e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   777 ELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQdslnQVNQVKETLEKELQTLKEKFASTSEEAV 856
Cdd:TIGR04523  160 KYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLK----KKIQKNKSLESQISELKKQNNQLKDNIE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   857 SAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQltKMN 936
Cdd:TIGR04523  236 KKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK--ELK 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   937 DELRLKERSVEELQLKLTKANENASFLQKSIGEvtLKAE--------QSQQQAARKHEEEKKELEEKLLELEKKMETSYN 1008
Cdd:TIGR04523  314 SELKNQEKKLEEIQNQISQNNKIISQLNEQISQ--LKKEltnsesenSEKQRELEEKQNEIEKLKKENQSYKQEIKNLES 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1009 QCQDLKAKYEKASSETKTKHEEI--LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKA-KSLTYLLTSAKKEIE 1085
Cdd:TIGR04523  392 QINDLESKIQNQEKLNQQKDEQIkkLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIiKNLDNTRESLETQLK 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1086 VMSEELRGLKS-------EKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSvnETLHLEKERVSEEKQVAE 1158
Cdd:TIGR04523  472 VLSRSINKIKQnleqkqkELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES--EKKEKESKISDLEDELNK 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1159 KRYqqehrdreslVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQV 1238
Cdd:TIGR04523  550 DDF----------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568937376  1239 KKLTAENlvlvKDKDDVIQKLQSAYEELVKDQKAlVQEIEDLTTEKKSAAEK 1290
Cdd:TIGR04523  620 EKAKKEN----EKLSSIIKNIKSKKNKLKQEVKQ-IKETIKEIRNKWPEIIK 666
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
681-1308 3.66e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.47  E-value: 3.66e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  681 ETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHlvemedtlNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEK 760
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIE--------ELIKEKE---KELEEVLREINEISSELPELREELEKLEKE 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  761 LLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLET---ERNAESSKANSITKELQEkelvLTGLQDSLNQVNQVKETL 837
Cdd:PRK03918  230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEErieELKKEIEELEEKVKELKE----LKEKAEEYIKLSEFYEEY 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  838 EKELQTLKEKFASTSEEAVSAQTRMQDTVNKlhqkeeqfnvlSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENd 917
Cdd:PRK03918  306 LDELREIEKRLSRLEEEINGIEERIKELEEK-----------EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEE- 373

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  918 IAEIMKMSGDNSsqLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEvtlkaeqsqqqaarkheeekkeleekll 997
Cdd:PRK03918  374 LERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE---------------------------- 423

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  998 elekkMETSYNQCQDLKAKYEKASSETKTKHE-EILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYL 1076
Cdd:PRK03918  424 -----LKKAIEELKKAKGKCPVCGRELTEEHRkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1077 LTSAkKEIEVMSEELRGLKSEKqlyaQEANALKLEKgsLLSKLIEVETKITLLQEDQQKLwsvnETLHLEKERVSEEKQV 1156
Cdd:PRK03918  499 KELA-EQLKELEEKLKKYNLEE----LEKKAEEYEK--LKEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDE 567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1157 AEKRYQQEHRDRESLVAEReklLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLmamsEKARAEKEHLEG 1236
Cdd:PRK03918  568 LEEELAELLKELEELGFES---VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL----DKAFEELAETEK 640

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937376 1237 QVKKLTAENLVLVKDKDDviqklqSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENL 1308
Cdd:PRK03918  641 RLEELRKELEELEKKYSE------EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1578-2105 4.12e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 4.12e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1578 LNAELKTCccEKNMLLRDGLNLQEECQKLNEEIREIQQTLI-LEKEARAKESEtslyennklhgrVVLLEEEIQRLRVCS 1656
Cdd:COG1196   218 LKEELKEL--EAELLLLKLRELEAELEELEAELEELEAELEeLEAELAELEAE------------LEELRLELEELELEL 283

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1657 EQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVA 1736
Cdd:COG1196   284 EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1737 LTERAEVLQDNKNLLAEKREmmLRNEEALKEKEKLEEsyfilQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLK 1816
Cdd:COG1196   364 EEALLEAEAELAEAEEELEE--LAEELLEALRAAAEL-----AAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1817 IRELEtlhsftaaQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKEnnlKTVEELNKSKELLSVENQKME 1896
Cdd:COG1196   437 EEEEE--------EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE---ELAEAAARLLLLLEAEADYEG 505

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1897 EFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKS-------LPSNTLRES 1969
Cdd:COG1196   506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratfLPLDKIRAR 585

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1970 EFRKDADEEKASLQKSISLTSALltekDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENK 2049
Cdd:COG1196   586 AALAAALARGAIGAAVDLVASDL----READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS 661

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568937376 2050 RQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAAL 2105
Cdd:COG1196   662 LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 344-1097 5.98e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 5.98e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   344 RKISGTTALQEALKEKQQH---IEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAK----MDQLRTMV 416
Cdd:TIGR02169  217 LKEKREYEGYELLKEKEALerqKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeQLRVKEKI 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   417 EAADREKVELLNQLEEEKRKVEDLqfrveEESITKGDLETQTKLEHARtkELEQSLLFEKTKADKLQRELEDTRVATVSE 496
Cdd:TIGR02169  297 GELEAEIASLERSIAEKERELEDA-----EERLAKLEAEIDKLLAEIE--ELEREIEEERKRRDKLTEEYAELKEELEDL 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   497 KSRIMELEKDLALRAQEVAELRRRLESSKPPGDvdmslSLLQEISALQEKLEAIHT---DHQGEMTSLKE---HFGAREE 570
Cdd:TIGR02169  370 RAELEEVDKEFAETRDELKDYREKLEKLKREIN-----ELKRELDRLQEELQRLSEelaDLNAAIAGIEAkinELEEEKE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   571 AFQKEIKA----LHTATEKLSKENES---LRSKLDHANKENSDVialwKSKLETAIASHQQAMEELKVSFS--KGIGTDS 641
Cdd:TIGR02169  445 DKALEIKKqewkLEQLAADLSKYEQElydLKEEYDRVEKELSKL----QRELAEAEAQARASEERVRGGRAveEVLKASI 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   642 AEFAELKTQIERLRLDYQHEIESLQSK-------QDSERSAHA----KEMETMQAKLMKIIKEKEDSLEAVKARLDSAED 710
Cdd:TIGR02169  521 QGVHGTVAQLGSVGERYATAIEVAAGNrlnnvvvEDDAVAKEAiellKRRKAGRATFLPLNKMRDERRDLSILSEDGVIG 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   711 Q--HLVEMEDtlnKLQEAEIKVKELEVLQAKYTEQSEVIGNFtsQLSAVKEKLLD--------LDALRKANS---EGKLE 777
Cdd:TIGR02169  601 FavDLVEFDP---KYEPAFKYVFGDTLVVEDIEAARRLMGKY--RMVTLEGELFEksgamtggSRAPRGGILfsrSEPAE 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   778 LETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVS 857
Cdd:TIGR02169  676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN 755

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   858 AQTRMQDTVNKLHQKEEQFNVLSSELEKL--------------------------RENLTDMEAKFKEKDDREDQLVKAK 911
Cdd:TIGR02169  756 VKSELKELEARIEELEEDLHKLEEALNDLearlshsripeiqaelskleeevsriEARLREIEQKLNRLTLEKEYLEKEI 835

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   912 EKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEvtLKAEQSQQQaaRKHEEEKKE 991
Cdd:TIGR02169  836 QELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE--LEAQLRELE--RKIEELEAQ 911

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   992 LEEKLLELEKKMETSYNQCQDLKAkYEKASSETKTKHEEI--LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADK 1069
Cdd:TIGR02169  912 IEKKRKRLSELKAKLEALEEELSE-IEDPKGEDEEIPEEElsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDE 990

                          810       820
                   ....*....|....*....|....*...
gi 568937376  1070 AKSLTYLLTSAKKEIEVMSEELRGLKSE 1097
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEEYEKKKRE 1018
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1376-2052 7.71e-10

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 64.36  E-value: 7.71e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1376 SSLTKLLEEIKTCRAITDSEciqlLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGL---NEKITYL 1452
Cdd:pfam05483   81 SKLYKEAEKIKKWKVSIEAE----LKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLikeNNATRHL 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1453 TSEKEVACQKVAKLKKQQDSLLKEKSALELqngDLLADRESSIKTIGDLRrkydQEATNRRIVMQEKMKL-LGNIDALKK 1531
Cdd:pfam05483  157 CNLLKETCARSAEKTKKYEYEREETRQVYM---DLNNNIEKMILAFEELR----VQAENARLEMHFKLKEdHEKIQHLEE 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1532 ELQER--KKENQ---------ELTSSKCDLSLLLKEAQDAKKNLEKEHT-------SMIQAKDNLNAELKTCCCEKNMLL 1593
Cdd:pfam05483  230 EYKKEinDKEKQvsllliqitEKENKMKDLTFLLEESRDKANQLEEKTKlqdenlkELIEKKDHLTKELEDIKMSLQRSM 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1594 RDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEE----EIQRLRVCSEQLQTENFTLtQE 1669
Cdd:pfam05483  310 STQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEllrtEQQRLEKNEDQLKIITMEL-QK 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1670 KTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILD-------DLRLNHEVALTERAE 1742
Cdd:pfam05483  389 KSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQarekeihDLEIQLTAIKTSEEH 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1743 VLQDNKNLLAEKREMMLRNEEALKEKEKLeesyfilQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELET 1822
Cdd:pfam05483  469 YLKEVEDLKTELEKEKLKNIELTAHCDKL-------LLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEE 541

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1823 lhsfTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEI 1902
Cdd:pfam05483  542 ----KEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEN 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1903 ETLKQAAAQKSQQLSALQEENVKLAEELGRTRdevtshQKLEEERSVLNNQlLEMKKSLPSNTLRESEFRKDADEEKASL 1982
Cdd:pfam05483  618 KALKKKGSAENKQLNAYEIKVNKLELELASAK------QKFEEIIDNYQKE-IEDKKISEEKLLEEVEKAKAIADEAVKL 690

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937376  1983 QKSISL-TSALLTEKDAELEKLRNEVTVLRGENATAKSLH-SVVQTLESDKVKLELKVKNLELQLKENKRQL 2052
Cdd:pfam05483  691 QKEIDKrCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYkNKEQEQSSAKAALEIELSNIKAELLSLKKQL 762
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
690-1230 1.05e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.91  E-value: 1.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  690 IIKEKEDSLEAVKARLDSAEDQHLVEmedtlnKLQEAEIKVKELEvlqakyteqsEVIGNFTSQLSAVKEKLLDLDALRK 769
Cdd:PRK02224  181 VLSDQRGSLDQLKAQIEEKEEKDLHE------RLNGLESELAELD----------EEIERYEEQREQARETRDEADEVLE 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  770 ANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFA 849
Cdd:PRK02224  245 EHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  850 STSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEK----DDREDQLvkakEKLENDIAEIMKMS 925
Cdd:PRK02224  325 ELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAreavEDRREEI----EELEEEIEELRERF 400

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  926 GDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSI--GEVTLKA----EQSQQQAARKHEEEKKELEEKLLEL 999
Cdd:PRK02224  401 GDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVeeAEALLEAgkcpECGQPVEGSPHVETIEEDRERVEEL 480

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1000 EKKMETSYNQCQDLKAKYEKASSETKT-----KHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLT 1074
Cdd:PRK02224  481 EAELEDLEEEVEEVEERLERAEDLVEAedrieRLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1075 yllTSAKKEIEVMSEELRGLKSEKQLYAQEANAL-KLEkgSLLSKLIEVETKITLLQEDQQKLWSVN----ETLHLEKER 1149
Cdd:PRK02224  561 ---AEAEEEAEEAREEVAELNSKLAELKERIESLeRIR--TLLAAIADAEDEIERLREKREALAELNderrERLAEKRER 635

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1150 VSE---------------EKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQ---EELLKMHMENDSLEASKVSMQVLIE 1211
Cdd:PRK02224  636 KREleaefdearieeareDKERAEEYLEQVEEKLDELREERDDLQAEIGAVEnelEELEELRERREALENRVEALEALYD 715

                         570
                  ....*....|....*....
gi 568937376 1212 ELrfckDKLMAMSEKARAE 1230
Cdd:PRK02224  716 EA----EELESMYGDLRAE 730
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 430-1296 1.52e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.45  E-value: 1.52e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   430 LEEEKRKVEDLQFRVEEESITKGDLEtQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLAL 509
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIID-LEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   510 RAQEVAELRrrlesskppgdvdmsLSLLQEISALQEKLEAIHTDHQGEMtslkehfgaREEAFQKEIKALHTATEKLSKE 589
Cdd:pfam02463  245 LLRDEQEEI---------------ESSKQEIEKEEEKLAQVLKENKEEE---------KEKKLQEEELKLLAKEEEELKS 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   590 NESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQ 669
Cdd:pfam02463  301 ELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   670 DSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKAR--------LDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYT 741
Cdd:pfam02463  381 LESERLSSAAKLKEEELELKSEEEKEAQLLLELARqledllkeEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   742 EQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQ-LEGAEKQIKNLETERNAESSKANSITKELQEKELVL 820
Cdd:pfam02463  461 LKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESkARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   821 TGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEK 900
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDK 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   901 DDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASfLQKSIGEVTLKAEQSQQQ 980
Cdd:pfam02463  621 RAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQEL-QEKAESELAKEEILRRQL 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   981 AARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDM 1060
Cdd:pfam02463  700 EIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1061 EELKTQADKAKSLTYLLTSAKKEIEVMSEElrgLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVN 1140
Cdd:pfam02463  780 REKTEKLKVEEEKEEKLKAQEEELRALEEE---LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEEL 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1141 ETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKL 1220
Cdd:pfam02463  857 ERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEE 936

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1221 MAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDD----VIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDN 1296
Cdd:pfam02463  937 PEELLLEEADEKEKEENNKEEEEERNKRLLLAKEelgkVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETC 1016
PTZ00121 PTZ00121
MAEBL; Provisional
 1383-2096 3.30e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 3.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1383 EEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNE-----KITYLTSEKE 1457
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKaeeakKADEAKKKAE 1325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1458 VACQKVAKLKKQQDSLlKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERK 1537
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEA-KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK 1404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1538 KENQELTSSKCDLslllKEAQDAKKNLEKEHTSmiqakdnlnAELKTCCCEKNMllrdglnlQEECQKLNEEIREIQQTL 1617
Cdd:PTZ00121 1405 KKADELKKAAAAK----KKADEAKKKAEEKKKA---------DEAKKKAEEAKK--------ADEAKKKAEEAKKAEEAK 1463

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1618 ILEKEARAKESETSLYENNKlhgRVVLLEEEIQRLRVCSEQLQtenftltqEKTNSEQKVEEIIKEKELLSAETAQLAAn 1697
Cdd:PTZ00121 1464 KKAEEAKKADEAKKKAEEAK---KADEAKKKAEEAKKKADEAK--------KAAEAKKKADEAKKAEEAKKADEAKKAE- 1531

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1698 iETLKSDFAALSKSKLELQELhscltKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEA-LKEKEKLEESYF 1776
Cdd:PTZ00121 1532 -EAKKADEAKKAEEKKKADEL-----KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEArIEEVMKLYEEEK 1605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1777 ILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDA-MQIMEQMTKEKTETLASLED 1855
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAeEAKKAEEDKKKAEEAKKAEE 1685

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1856 TKQTNArlqnELDTLKENNLKTVEELNKSKEllsVENQKMEEFKKEIETLKQaaaqKSQQLSALQEENVKLAEELGRTRD 1935
Cdd:PTZ00121 1686 DEKKAA----EALKKEAEEAKKAEELKKKEA---EEKKKAEELKKAEEENKI----KAEEAKKEAEEDKKKAEEAKKDEE 1754

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1936 EVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKASlqKSISLTSALLTEKDAELEKLRNEVTVLRGENA 2015
Cdd:PTZ00121 1755 EKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKI--KDIFDNFANIIEGGKEGNLVINDSKEMEDSAI 1832

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 2016 TAKSLHSVVQTLESDKVKlelkvknlelQLKENKRQLSSSSGNTDAQA-------EEDERAQESQQMIDFLNSVIVDLQR 2088
Cdd:PTZ00121 1833 KEVADSKNMQLEEADAFE----------KHKFNKNNENGEDGNKEADFnkekdlkEDDEEEIEEADEIEKIDKDDIEREI 1902


                  ....*...
gi 568937376 2089 KNQDLKMK 2096
Cdd:PTZ00121 1903 PNNNMAGK 1910
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 810-1874 3.36e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 62.50  E-value: 3.36e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   810 TKELQEK-ELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLH-------QKEEQFNVLSS 881
Cdd:pfam01576   17 VKERQQKaESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHelesrleEEEERSQQLQN 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   882 ELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENAS 961
Cdd:pfam01576   97 EKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAK 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   962 FLQK---------SIGEVTLKAEQSQQQAARKHEEEKKELEEKLLElekkmetsynQCQDLKAKYEKASSETKTKHEEiL 1032
Cdd:pfam01576  177 SLSKlknkheamiSDLEERLKKEEKGRQELEKAKRKLEGESTDLQE----------QIAELQAQIAELRAQLAKKEEE-L 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1033 QNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTyllTSAKKEIEVMSEELRGLKSEKQ------LYAQEAN 1106
Cdd:pfam01576  246 QAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAAR---NKAEKQRRDLGEELEALKTELEdtldttAAQQELR 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1107 ALKLEKGSLLSKLIEVETKI--TLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKryqqehrDRESLVAEREKLLKEINA 1184
Cdd:pfam01576  323 SKREQEVTELKKALEEETRSheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEK-------AKQALESENAELQAELRT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1185 AQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYE 1264
Cdd:pfam01576  396 LQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1265 ELVKDQKALVQeiedLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLS 1344
Cdd:pfam01576  476 LLQEETRQKLN----LSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQ 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1345 TEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTklleeiktcraitdsecIQLLHEKESLAASERTlLAEKEELLSEN 1424
Cdd:pfam01576  552 RELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLL-----------------VDLDHQRQLVSNLEKK-QKKFDQMLAEE 613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1425 RIITeklSKQSEEVARLEMGLNEKITyltsekevacqKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDL--- 1501
Cdd:pfam01576  614 KAIS---ARYAEERDRAEAEAREKET-----------RALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVgkn 679

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1502 -------RRKYDQEATNRRIVMQE-----------KMKLLGNIDALK----KELQERKKENQEltsskcDLSLLLKEAQD 1559
Cdd:pfam01576  680 vhelersKRALEQQVEEMKTQLEEledelqatedaKLRLEVNMQALKaqfeRDLQARDEQGEE------KRRQLVKQVRE 753

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1560 AKKNLEKEHTSMIQA---KDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEAR------AKESET 1630
Cdd:pfam01576  754 LEAELEDERKQRAQAvaaKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRdeilaqSKESEK 833

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1631 SLyenNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSK 1710
Cdd:pfam01576  834 KL---KNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLND 910

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1711 SKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMmlrnEEALKEKEKLEESYFilqkeISQLAQTNS 1790
Cdd:pfam01576  911 RLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEM----EGTVKSKFKSSIAAL-----EAKIAQLEE 981

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1791 HISANLLESQSENRTLRKDKSKL--TLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELD 1868
Cdd:pfam01576  982 QLEQESRERQAANKLVRRTEKKLkeVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELD 1061


                   ....*.
gi 568937376  1869 TLKENN 1874
Cdd:pfam01576 1062 DATESN 1067
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1148-1787 4.25e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 4.25e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1148 ERVSEEKQVAEK----RYQQEHRDRESLVAEREKLLKEINAAQEELlkmhmendsleaskvsmqvlieelrfckDKLMAM 1223
Cdd:COG1196   203 EPLERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELEAEL----------------------------EELEAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1224 SEKARAEKEHLEGQVKKLTAEnlvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKA 1303
Cdd:COG1196   255 LEELEAELAELEAELEELRLE-----------LEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1304 ERENLLQTNRDLQFEKDTLRQGQEKLSASLEAT-LQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLL 1382
Cdd:COG1196   324 ELAELEEELEELEEELEELEEELEEAEEELEEAeAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1383 EEIKTCRAITDsECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQK 1462
Cdd:COG1196   404 ELEEAEEALLE-RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1463 VAKLKKQQDSLLKEKSALELQNGDLLADREssIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERkkenqe 1542
Cdd:COG1196   483 LEELAEAAARLLLLLEAEADYEGFLEGVKA--ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE------ 554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1543 ltsskcDLSLLLKEAQDAKKNLEKEHTSMIQAKdnlnaelktccceknMLLRDGLNLQEECQKLNEEIREIQQTLILEKE 1622
Cdd:COG1196   555 ------DDEVAAAAIEYLKAAKAGRATFLPLDK---------------IRARAALAAALARGAIGAAVDLVASDLREADA 613

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1623 ARAKESETSL---YENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIE 1699
Cdd:COG1196   614 RYYVLGDTLLgrtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1700 TLKSDFAALSKSKLELQELhscltkiLDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQ 1779
Cdd:COG1196   694 ELEEALLAEEEEERELAEA-------EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766


                  ....*...
gi 568937376 1780 KEISQLAQ 1787
Cdd:COG1196   767 RELERLER 774
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1256-1846 4.73e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.00  E-value: 4.73e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1256 IQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEkqmsLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEA 1335
Cdd:PRK03918  157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1336 TLQVKQLLsteaETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKtcraitdsECIQLLHEKESLAASERTLLA 1415
Cdd:PRK03918  233 LEELKEEI----EELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE--------EKVKELKELKEKAEEYIKLSE 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1416 EKEELLSENRIITEKLSKQSEEVArlemGLNEKITYLTSEKEvacqKVAKLKKQQDSLLKEKSALE-----LQNGDLLAD 1490
Cdd:PRK03918  301 FYEEYLDELREIEKRLSRLEEEIN----GIEERIKELEEKEE----RLEELKKKLKELEKRLEELEerhelYEEAKAKKE 372

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1491 RESSIK------TIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSK-----CDLSL------- 1552
Cdd:PRK03918  373 ELERLKkrltglTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvCGRELteehrke 452

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1553 LLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTccCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEK-EARAKESETS 1631
Cdd:PRK03918  453 LLEEYTAELKRIEKELKEIEEKERKLRKELRE--LEKVLKKESELIKLKELAEQLKELEEKLKKYNLEElEKKAEEYEKL 530

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1632 LYENNKLHGRVVLLEEEIQRLrvcsEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAET-AQLAANIETLKS---DFAA 1707
Cdd:PRK03918  531 KEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDELEEELAELLKELEELGFESvEELEERLKELEPfynEYLE 606

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1708 LSKSKLELQELHscltKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLR-----NEEALKEKEKLEESYFILQKEI 1782
Cdd:PRK03918  607 LKDAEKELEREE----KELKKLEEELDKAFEELAETEKRLEELRKELEELEKKyseeeYEELREEYLELSRELAGLRAEL 682

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376 1783 SQLAQTNSHISANLLESQSENRTLRKDKSKLTL-------------KIRELETLHSFTA-AQTAEDAMQIMEQMTKEK 1846
Cdd:PRK03918  683 EELEKRREEIKKTLEKLKEELEEREKAKKELEKlekalerveelreKVKKYKALLKERAlSKVGEIASEIFEELTEGK 760
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 334-964 1.23e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 60.51  E-value: 1.23e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   334 LLTETSSRYARKISGTTALQEALKEKQQHIEQLLaERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDqlr 413
Cdd:pfam05483  159 LLKETCARSAEKTKKYEYEREETRQVYMDLNNNI-EKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKE--- 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   414 tmVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQsllfektKADKLQRELEDTRVAT 493
Cdd:pfam05483  235 --INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIE-------KKDHLTKELEDIKMSL 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   494 VSEKSRIMELEKDLALRAQEVAELRRRLESSkppgdvdmslslLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQ 573
Cdd:pfam05483  306 QRSMSTQKALEEDLQIATKTICQLTEEKEAQ------------MEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLE 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   574 KEIKALHTATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIASHQQAMEELKVSFSKGIG---TDSAEFA 645
Cdd:pfam05483  374 KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELkkilaEDEKLLDEKKQFEKIAEELKGKEQELIFllqAREKEIH 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   646 ELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhlvemEDTLNKLQE 725
Cdd:pfam05483  454 DLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQ-----EDIINCKKQ 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   726 AEIKVKELEVLQAKYT----EQSEVIGNFTSQLSAVKEKL---------LDLDALRKANSEGKLELE--TLRQQLEGAEK 790
Cdd:pfam05483  529 EERMLKQIENLEEKEMnlrdELESVREEFIQKGDEVKCKLdkseenarsIEYEVLKKEKQMKILENKcnNLKKQIENKNK 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   791 QIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQ----VKETLEKELQTLKEKFASTSEEAVSAQTRMQDTV 866
Cdd:pfam05483  609 NIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQkfeeIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAV 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   867 NKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDN-SSQLTKMNDELRLKERS 945
Cdd:pfam05483  689 KLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNiKAELLSLKKQLEIEKEE 768

                          650
                   ....*....|....*....
gi 568937376   946 VEELQLkltKANENASFLQ 964
Cdd:pfam05483  769 KEKLKM---EAKENTAILK 784
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
354-888 1.24e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.70  E-value: 1.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  354 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALAR-DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEE 432
Cdd:COG4913   255 EPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRG 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  433 EK-RKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRimeLEKDLALRA 511
Cdd:COG4913   335 NGgDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEA---LEEALAEAE 411

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  512 QEVAELRRRLESskppgdvdmslsLLQEISALQEKLEAIHTDHQGEMTSLKEHFG----------------AREEAFQKE 575
Cdd:COG4913   412 AALRDLRRELRE------------LEAEIASLERRKSNIPARLLALRDALAEALGldeaelpfvgelievrPEEERWRGA 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  576 I-KALHT--------------ATEKLskENESLRSKLDhankenSDVIALWKSKLETAIASHQQAMEELKVSfskgigtD 640
Cdd:COG4913   480 IeRVLGGfaltllvppehyaaALRWV--NRLHLRGRLV------YERVRTGLPDPERPRLDPDSLAGKLDFK-------P 544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  641 SAEFAELKTQIERlRLDYqHEIESLQSKQDSERS------------AHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSA 708
Cdd:COG4913   545 HPFRAWLEAELGR-RFDY-VCVDSPEELRRHPRAitragqvkgngtRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAEL 622

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  709 EDQhlvemedtlnkLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQ------LSAVKEKLLDLDALRKANSEGKLELETLR 782
Cdd:COG4913   623 EEE-----------LAEAEERLEALEAELDALQERREALQRLAEYswdeidVASAEREIAELEAELERLDASSDDLAALE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  783 QQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELqtLKEKFASTSEEAVSAQTRm 862
Cdd:COG4913   692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAVERELR- 768

                         570       580
                  ....*....|....*....|....*.
gi 568937376  863 QDTVNKLHQKEEQFNVLSSELEKLRE 888
Cdd:COG4913   769 ENLEERIDALRARLNRAEEELERAMR 794
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
337-838 1.56e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.56e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  337 ETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDqhvleleakmdqlrtmV 416
Cdd:PRK02224  241 EVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAG----------------L 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  417 EAADREKVELlnQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSE 496
Cdd:PRK02224  305 DDADAEAVEA--RREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDR 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  497 KSRIMELEKdlalraqEVAELRRRLESSkpPGDVDMSLSLLQEisaLQEKLEAIHTDHQGEMTSLKEHFGAREEAFQ--- 573
Cdd:PRK02224  383 REEIEELEE-------EIEELRERFGDA--PVDLGNAEDFLEE---LREERDELREREAELEATLRTARERVEEAEAlle 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  574 -----------KEIKALHTATEKlSKENESLRSKLDHANKENSDVialwKSKLETA-----IASHQQAMEELKVSFSKGI 637
Cdd:PRK02224  451 agkcpecgqpvEGSPHVETIEED-RERVEELEAELEDLEEEVEEV----EERLERAedlveAEDRIERLEERREDLEELI 525

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  638 GTDSAEFAELKTQIERLRldyqHEIESLQSKQDSERSAHAKEMETMQAKLMKiIKEKEDSLEAVKARLDSAEDqhlveME 717
Cdd:PRK02224  526 AERRETIEEKRERAEELR----ERAAELEAEAEEKREAAAEAEEEAEEAREE-VAELNSKLAELKERIESLER-----IR 595

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  718 DTLNKLQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKAN--SEGKLELETLRQQLEGAEKQIKNL 795
Cdd:PRK02224  596 TLLAAIADAE---DEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEAriEEAREDKERAEEYLEQVEEKLDEL 672

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 568937376  796 ETERNAESSKANSITKELQEkelvLTGLQDSLNQVNQVKETLE 838
Cdd:PRK02224  673 REERDDLQAEIGAVENELEE----LEELRERREALENRVEALE 711
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1430-1962 2.27e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 59.65  E-value: 2.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1430 KLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQngdlLADRESSIKTIGDLRRKYDQEA 1509
Cdd:TIGR04523  128 KLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKE----KLNIQKNIDKIKNKLLKLELLL 203

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1510 TNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEK 1589
Cdd:TIGR04523  204 SNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKI 283

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1590 NMLLRDGLNLQEECQKLN----EEIREIQQTLILEKEARAKESETSLYENNKlhgRVVLLEEEIQRLRVCSEQLQTENFT 1665
Cdd:TIGR04523  284 KELEKQLNQLKSEISDLNnqkeQDWNKELKSELKNQEKKLEEIQNQISQNNK---IISQLNEQISQLKKELTNSESENSE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1666 LTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQ 1745
Cdd:TIGR04523  361 KQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNS 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1746 DNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHS 1825
Cdd:TIGR04523  441 EIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1826 F--TAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNA------RLQNELDTLKENNLKTVEELNKSKELLSVENQKMEE 1897
Cdd:TIGR04523  521 SlkEKIEKLESEKKEKESKISDLEDELNKDDFELKKENlekeidEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKD 600

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937376  1898 FKKEIETLKQAAAQKSQQLSALQEENVKLAEELgrtRDEVTSHQKLEEERSVLNNQLLEMKKSLP 1962
Cdd:TIGR04523  601 LIKEIEEKEKKISSLEKELEKAKKENEKLSSII---KNIKSKKNKLKQEVKQIKETIKEIRNKWP 662
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 354-1195 2.46e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.60  E-value: 2.46e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   354 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEE 433
Cdd:pfam02463  173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   434 KRKVEDLQFRVEEESITKGDL----ETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLAL 509
Cdd:pfam02463  253 IESSKQEIEKEEEKLAQVLKEnkeeEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKK 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   510 RAQEVAELRRRLESSKPPGDVDmsLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKE 589
Cdd:pfam02463  333 EKEEIEELEKELKELEIKREAE--EEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   590 NESLRSKLDHA----NKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESL 665
Cdd:pfam02463  411 LELARQLEDLLkeekKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   666 QSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKAR----------LDSAEDQHLVEMEDTLNKLQEAEIKVKELEV 735
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGrlgdlgvaveNYKVAISTAVIVEVSATADEVEERQKLVRAL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   736 LQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQE 815
Cdd:pfam02463  571 TELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   816 KELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEA 895
Cdd:pfam02463  651 GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   896 KFKEKDDREDQLVKAKEKLENDIaeimKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAE 975
Cdd:pfam02463  731 QDKINEELKLLKQKIDEEEEEEE----KSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   976 QSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRD 1055
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1056 LMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLyaQEANALKLEKGSLLSKLIEVETKITLLQEDQQK 1135
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILL--KYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1136 LWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHME 1195
Cdd:pfam02463  965 LLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLE 1024
PTZ00121 PTZ00121
MAEBL; Provisional
 357-950 2.89e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.38  E-value: 2.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  357 KEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAaDREKVELLNQLEEEKRK 436
Cdd:PTZ00121 1341 AKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEE-DKKKADELKKAAAAKKK 1419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  437 VEDLQFRVEEesITKGDlETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVA-----TVSEKSRIMELEKDLALRA 511
Cdd:PTZ00121 1420 ADEAKKKAEE--KKKAD-EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAdeakkKAEEAKKADEAKKKAEEAK 1496

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  512 QEVAELRRRLESSKPPgdvdmslsllQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKAlhtaTEKLSKENE 591
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKA----------DEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK----AEELKKAEE 1562

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  592 slRSKLDHANKENSDVIALWKSkletaiashqqameelkvsfskgigtdsaefAELKTQIERLRLDYQHEIESLQSKQDS 671
Cdd:PTZ00121 1563 --KKKAEEAKKAEEDKNMALRK-------------------------------AEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  672 ERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELE----VLQAKYTEQSEvi 747
Cdd:PTZ00121 1610 EEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkkkAEEAKKAEEDE-- 1687

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  748 GNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKelvltglqdsl 827
Cdd:PTZ00121 1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK----------- 1756

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  828 NQVNQVKETLEKELQTLKEKFASTSEEAVSAQ--TRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKF----KEKD 901
Cdd:PTZ00121 1757 KKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEdeKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEdsaiKEVA 1836

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 568937376  902 DREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQ 950
Cdd:PTZ00121 1837 DSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIE 1885
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1035-1617 6.19e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.21  E-value: 6.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1035 LQKMLADTEDKLKAAQEANRDLMQDM-----EELKTQADKAKSLTYLLTSAKKEIEVMSEELRglkSEKQLYAQEANALK 1109
Cdd:pfam15921  247 LEALKSESQNKIELLLQQHQDRIEQLiseheVEITGLTEKASSARSQANSIQSQLEIIQEQAR---NQNSMYMRQLSDLE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1110 LEKGSLLSKLIEVETkitlLQEDQQKlwsvnetlHLEKERVSEEKQVAEKRYQQEHRDRES--LVAEREKLLKEINAAQE 1187
Cdd:pfam15921  324 STVSQLRSELREAKR----MYEDKIE--------ELEKQLVLANSELTEARTERDQFSQESgnLDDQLQKLLADLHKREK 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1188 ELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELV 1267
Cdd:pfam15921  392 ELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1268 KDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQfekdtlrqgqeKLSASLEATLQVKQLLSTEA 1347
Cdd:pfam15921  472 STKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-----------KLRSRVDLKLQELQHLKNEG 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1348 ETLR-TQLDCASKALRKAELD--MRQLQTSNSSLTKLLEEIKTCRAITDSECIQLlhEKEslaASERTLLAEKEELLSEN 1424
Cdd:pfam15921  541 DHLRnVQTECEALKLQMAEKDkvIEILRQQIENMTQLVGQHGRTAGAMQVEKAQL--EKE---INDRRLELQEFKILKDK 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1425 RiiTEKLSKQSEEVARLEMglnEKITYLTSEKEvACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKtigDLRRK 1504
Cdd:pfam15921  616 K--DAKIRELEARVSDLEL---EKVKLVNAGSE-RLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR---NFRNK 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1505 YDQ-EATNRRIVMQEKmKLLGNIDALKKELQERKKEN-----------QELTSSKCDLSLLLKEAQ---DAKKNLEKEHT 1569
Cdd:pfam15921  687 SEEmETTTNKLKMQLK-SAQSELEQTRNTLKSMEGSDghamkvamgmqKQITAKRGQIDALQSKIQfleEAMTNANKEKH 765

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 568937376  1570 SMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTL 1617
Cdd:pfam15921  766 FLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVAL 813
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
648-1244 1.09e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.36  E-value: 1.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  648 KTQIERLRLDYQHEIESLQS----KQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhLVEMEDTLNKL 723
Cdd:PRK02224  175 RLGVERVLSDQRGSLDQLKAqieeKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEV-LEEHEERREEL 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  724 QEAEikvKELEVLQAKYTEqsevignftsqlsAVKEKlldlDALRKansegklELETLRQQLEGAEKQIKNLETERNAES 803
Cdd:PRK02224  254 ETLE---AEIEDLRETIAE-------------TERER----EELAE-------EVRDLRERLEELEEERDDLLAEAGLDD 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  804 SKANSITKELQEKELVLTGLQDSLNQV-------NQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQF 876
Cdd:PRK02224  307 ADAEAVEARREELEDRDEELRDRLEECrvaaqahNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEI 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  877 NVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAeimkmsgdnssqltkmndELRLKERSVEElqlkltKA 956
Cdd:PRK02224  387 EELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREA------------------ELEATLRTARE------RV 442

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  957 NENASFLqksigEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKT-----KHEEI 1031
Cdd:PRK02224  443 EEAEALL-----EAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAedrieRLEER 517

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1032 LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTyllTSAKKEIEVMSEELRGLKSEKQLYAQEANAL-KL 1110
Cdd:PRK02224  518 REDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA---AEAEEEAEEAREEVAELNSKLAELKERIESLeRI 594

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1111 EkgSLLSKLIEVETKITLLQEDQQKLWSVN----ETLHLEKERVSE-EKQVAEKRYQQEHRDRESLVAEREKLLKEINAA 1185
Cdd:PRK02224  595 R--TLLAAIADAEDEIERLREKREALAELNderrERLAEKRERKRElEAEFDEARIEEAREDKERAEEYLEQVEEKLDEL 672

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937376 1186 QEellkmhmENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARA------EKEHLEGQVKKLTAE 1244
Cdd:PRK02224  673 RE-------ERDDLQAEIGAVENELEELEELRERREALENRVEAlealydEAEELESMYGDLRAE 730
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 768-1522 1.25e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 57.29  E-value: 1.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   768 RKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTglqdslnqvnQVKETLEKELQTLKEk 847
Cdd:TIGR00618  165 KKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYH----------ERKQVLEKELKHLRE- 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   848 fastseeavsAQTRMQDTVNKLHQKEEQFNvlssELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEND-----IAEIM 922
Cdd:TIGR00618  234 ----------ALQQTQQSHAYLTQKREAQE----EQLKKQQLLKQLRARIEELRAQEAVLEETQERINRArkaapLAAHI 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   923 KMSGDNSSQLTKMNDELRLKERSVE-ELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEK 1001
Cdd:TIGR00618  300 KAVTQIEQQAQRIHTELQSKMRSRAkLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQ 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1002 KMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLK-AAQEANRDLMQDMEELKTQAdkaksLTYLLTSA 1080
Cdd:TIGR00618  380 HIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQlAHAKKQQELQQRYAELCAAA-----ITCTAQCE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1081 KKEIEVMSEELRGLKSEKQLYAQEANALKLEKgsllSKLIEVETKITLLQEDQQKLwsVNETLHLEKE------------ 1148
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQQLQTKEQIHLQET----RKKAVVLARLLELQEEPCPL--CGSCIHPNPArqdidnpgpltr 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1149 RVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKAR 1228
Cdd:TIGR00618  529 RMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAED 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1229 AEKEHLEGQVKKLTAEnlvlvKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSaaEKQMSLDNTCLTLKAERENL 1308
Cdd:TIGR00618  609 MLACEQHALLRKLQPE-----QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVR--EHALSIRVLPKELLASRQLA 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1309 LQT----NRDLQFEKDTLRQGQEKLSASLEATL-------QVKQLLSTEAETLRTQLDCASKALRKAELDMR---QLQTS 1374
Cdd:TIGR00618  682 LQKmqseKEQLTYWKEMLAQCQTLLRELETHIEeydrefnEIENASSSLGSDLAAREDALNQSLKELMHQARtvlKARTE 761

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1375 NSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENR--IITEKLSKQSEEVARLEMGLN--EKIT 1450
Cdd:TIGR00618  762 AHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIpsDEDILNLQCETLVQEEEQFLSrlEEKS 841

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937376  1451 YLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKL 1522
Cdd:TIGR00618  842 ATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYANVRLANQSE 913
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 679-1132 1.48e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.95  E-value: 1.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   679 EMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhlveMEDTLNKLQEAeikVKELEVLQAKYTEQSEVIGNFTSQLSAVK 758
Cdd:TIGR04523  222 ELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ----LNQLKDEQNKI---KKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   759 EKLLDLDALRKAN--SEGKLELETLRQQLEGAEKQ--------------IKNLETERNAESSKANSITKELQEKELVLTG 822
Cdd:TIGR04523  295 SEISDLNNQKEQDwnKELKSELKNQEKKLEEIQNQisqnnkiisqlneqISQLKKELTNSESENSEKQRELEEKQNEIEK 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   823 LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDD 902
Cdd:TIGR04523  375 LKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   903 REDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAA 982
Cdd:TIGR04523  455 IIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKK 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   983 RKHEeekkeleekllelekkmETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKmLADTEDKLKAAQEANRDLMQDME- 1061
Cdd:TIGR04523  535 EKES-----------------KISDLEDELNKDDFELKKENLEKEIDEKNKEIEE-LKQTQKSLKKKQEEKQELIDQKEk 596

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376  1062 -------ELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQED 1132
Cdd:TIGR04523  597 ekkdlikEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTK 674
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
835-1364 1.50e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  835 ETLEkELQTLKEKFASTSEEAvsAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKL 914
Cdd:COG4913   252 ELLE-PIRELAERYAAARERL--AELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEL 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  915 ENDIAEImkmSGDNSSQLtkmndelrlkERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEE 994
Cdd:COG4913   329 EAQIRGN---GGDRLEQL----------EREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEA 395

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  995 KLLELEKKMETSYnqcqDLKAKYEKASSETKTKHEEIL----------QNLQKMLADTEDKLKAAQEANR---DLMQDME 1061
Cdd:COG4913   396 LEEELEALEEALA----EAEAALRDLRRELRELEAEIAslerrksnipARLLALRDALAEALGLDEAELPfvgELIEVRP 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1062 E-----------LKTQAdkakslTYLLTSAKKEIEV--------MSEELRGLKSEKQLyaQEANALKLEKGSLLSKLIEV 1122
Cdd:COG4913   472 EeerwrgaiervLGGFA------LTLLVPPEHYAAAlrwvnrlhLRGRLVYERVRTGL--PDPERPRLDPDSLAGKLDFK 543

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1123 ETKIT--LLQE--DQQKLWSVN--ETLHLEKERVSEEKQVAEKRYQQEHRDR-----------------ESLVAEREKLL 1179
Cdd:COG4913   544 PHPFRawLEAElgRRFDYVCVDspEELRRHPRAITRAGQVKGNGTRHEKDDRrrirsryvlgfdnraklAALEAELAELE 623

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1180 KEINAAQEELLKMHMENDSLEASKVSMQVLiEELRFCKDKLMAmsekARAEKEHLEGQVKKLTAENlvlvkdkdDVIQKL 1259
Cdd:COG4913   624 EELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVAS----AEREIAELEAELERLDASS--------DDLAAL 690

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1260 QSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEatlQV 1339
Cdd:COG4913   691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVER---EL 767

                         570       580
                  ....*....|....*....|....*
gi 568937376 1340 KQLLSTEAETLRTQLDCASKALRKA 1364
Cdd:COG4913   768 RENLEERIDALRARLNRAEEELERA 792
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2169-2185 1.59e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.59e-07
                           10
                   ....*....|....*..
gi 568937376  2169 RPYCEICEMFGHWATNC 2185
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 938-1775 1.97e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.52  E-value: 1.97e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   938 ELRLKERSVEELqLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKheeekkeLEEKLLELEKKMETSYNQCQDLKAKY 1017
Cdd:pfam02463  164 GSRLKRKKKEAL-KKLIEETENLAELIIDLEELKLQELKLKEQAKKA-------LEYYQLKEKLELEEEYLLYLDYLKLN 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1018 EKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTylltsakKEIEVMSEELRGLKSE 1097
Cdd:pfam02463  236 EERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLA-------KEEEELKSELLKLERR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1098 KQLYAQEANALKLEKGSLLSKLIEVETKITllqEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREK 1177
Cdd:pfam02463  309 KVDDEEKLKESEKEKKKAEKELKKEKEEIE---ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1178 LLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKL-TAENLVLVKDKDDVI 1256
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEkEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1257 QKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEAT 1336
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1337 LQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQlLHEKESLAASERTLLAE 1416
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQ-LDKATLEADEDDKRAKV 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1417 KEELLSENRIITEKLSK-----QSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADR 1491
Cdd:pfam02463  625 VEGILKDTELTKLKESAkakesGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKK 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1492 ESSIKTIgdLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSK------CDLSLLLKEAQDAKKNLE 1565
Cdd:pfam02463  705 EQREKEE--LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKkeekeeEKSELSLKEKELAEEREK 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1566 KEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVV-L 1644
Cdd:pfam02463  783 TEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEeE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1645 LEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAalsKSKLELQELHSCLTK 1724
Cdd:pfam02463  863 ITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIK---EEAEILLKYEEEPEE 939

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 568937376  1725 ILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESY 1775
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERY 990
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 743-961 2.09e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 2.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  743 QSEVIGNFTSQLSAVKEKLL----DLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKEL 818
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAelekELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  819 VLTGLQDSLNQVNQvkeTLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFK 898
Cdd:COG4942    98 ELEAQKEELAELLR---ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568937376  899 EKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENAS 961
Cdd:COG4942   175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1751-2127 3.00e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 56.24  E-value: 3.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1751 LAEKREMMLRNEEALKEKEKLEESYFILQkeiSQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAq 1830
Cdd:COG5022   805 LLGSRKEYRSYLACIIKLQKTIKREKKLR---ETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELA- 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1831 taedamqimEQMTKEKTETLASLEDTKQTNARLQNEL---------DTLKENNLKTvEELNKSKELL---SVENQKMEEF 1898
Cdd:COG5022   881 ---------ERQLQELKIDVKSISSLKLVNLELESEIielkkslssDLIENLEFKT-ELIARLKKLLnniDLEEGPSIEY 950

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1899 KK-----EIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLR------ 1967
Cdd:COG5022   951 VKlpelnKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEvaelqs 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1968 ESEFRKDADEEKASLQKSISLTSALLtekdAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL-ELKVKNLELqlk 2046
Cdd:COG5022  1031 ASKIISSESTELSILKPLQKLKGLLL----LENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLkTINVKDLEV--- 1103

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 2047 eNKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQSKK 2126
Cdd:COG5022  1104 -TNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRL 1182


                  .
gi 568937376 2127 K 2127
Cdd:COG5022  1183 Y 1183
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1342-1908 5.14e-07

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 55.13  E-value: 5.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1342 LLSTEAETLRTQLDCASKalRKAELDMRqlqtsnsslTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELL 1421
Cdd:pfam05557   31 ELEKKASALKRQLDRESD--RNQELQKR---------IRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1422 SENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNgDLLADRESSIKtigDL 1501
Cdd:pfam05557  100 ADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQ-SSLAEAEQRIK---EL 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1502 RRKYDQEATNRRIVMQEKMKLLgNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQA------K 1575
Cdd:pfam05557  176 EFEIQSQEQDSEIVKNSKSELA-RIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKLEREEKYREEAatleleK 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1576 DNLNAELKTCcceKNMLLRDGLNLQEEcQKLNEEIREIQQTLILEKEarakESETSLYENNKLHGRVVLLEEEIQRLRVC 1655
Cdd:pfam05557  255 EKLEQELQSW---VKLAQDTGLNLRSP-EDLSRRIEQLQQREIVLKE----ENSSLTSSARQLEKARRELEQELAQYLKK 326

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1656 SEQLQTENftltqeKTNSEQKvEEIIKEKELLSAETAQLAANIETLKSDFaALSKSKLELQELHSCLTKILDDLRlNHEV 1735
Cdd:pfam05557  327 IEDLNKKL------KRHKALV-RRLQRRVLLLTKERDGYRAILESYDKEL-TMSNYSPQLLERIEEAEDMTQKMQ-AHNE 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1736 ALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFIlQKEISQLAQTNSHISA---------NLLESQSENRTL 1806
Cdd:pfam05557  398 EMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYS-KEEVDSLRRKLETLELerqrlreqkNELEMELERRCL 476

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1807 RKDKSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLkenNLKTVEELNKSKE 1886
Cdd:pfam05557  477 QGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTM---NFKEVLDLRKELE 553

                          570       580
                   ....*....|....*....|...
gi 568937376  1887 LLSVENQKMEE-FKKEIETLKQA 1908
Cdd:pfam05557  554 SAELKNQRLKEvFQAKIQEFRDV 576
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 402-1280 7.47e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.84  E-value: 7.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   402 VLELEAKMDQLRTMVEA--ADREKVELLNQLEEEK--RKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKT 477
Cdd:pfam12128  188 MHSKEGKFRDVKSMIVAilEDDGVVPPKSRLNRQQveHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGY 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   478 KADKLQRELEDTRVATVSE--KSRIMELEKDLAlraQEVAELRRRLESSKppgdvdmslsllQEISALQEKLEAIHTDH- 554
Cdd:pfam12128  268 KSDETLIASRQEERQETSAelNQLLRTLDDQWK---EKRDELNGELSAAD------------AAVAKDRSELEALEDQHg 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   555 ---QGEMTSLKEH------FGAREEAFQKEIKALHTATEKLSKENESLRSKLDhanKENSDVIALWKSKLE--------- 616
Cdd:pfam12128  333 aflDADIETAAADqeqlpsWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK---EQNNRDIAGIKDKLAkireardrq 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   617 -TAIASHQQAME-ELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAhaKEMETMQAKLMKIIKEK 694
Cdd:pfam12128  410 lAVAEDDLQALEsELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFD--ERIERAREEQEAANAEV 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   695 EDsLEAVKARLDSAEDQHLVemedtlnKLQEAEIKVKELEvlqakyteqsevignftSQLSAVKEKLLDldalrkanSEG 774
Cdd:pfam12128  488 ER-LQSELRQARKRRDQASE-------ALRQASRRLEERQ-----------------SALDELELQLFP--------QAG 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   775 KLeLETLRQQLEGAEKQI-KNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVnQVKETLEKElQTLKEKFASTSE 853
Cdd:pfam12128  535 TL-LHFLRKEAPDWEQSIgKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRI-DVPEWAASE-EELRERLDKAEE 611

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   854 EAVSAQTRMQdtvnklhQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKmsgdnssqlt 933
Cdd:pfam12128  612 ALQSAREKQA-------AAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALA---------- 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   934 kmnDELRLKERSVEELqlkltkanenasflqksigEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDL 1013
Cdd:pfam12128  675 ---ERKDSANERLNSL-------------------EAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLA 732

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1014 KAKYEKASSETKTKHEeiLQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAksltylltsAKKEIEVMSEElrg 1093
Cdd:pfam12128  733 LLKAAIAARRSGAKAE--LKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERI---------AVRRQEVLRYF--- 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1094 lKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSvnetlHLEKERVSEEKqvaekryqQEHRDRESLVA 1173
Cdd:pfam12128  799 -DWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRA-----KLEMERKASEK--------QQVRLSENLRG 864

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1174 EREkLLKEINAaqeelLKMHMENDSLEASKVSMQVLIEELrfcKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKD 1253
Cdd:pfam12128  865 LRC-EMSKLAT-----LKEDANSEQAQGSIGERLAQLEDL---KLKRDYLSESVKKYVEHFKNVIADHSGSGLAETWESL 935

                          890       900
                   ....*....|....*....|....*..
gi 568937376  1254 DVIQKLQSAYEELVKDQKALVQEIEDL 1280
Cdd:pfam12128  936 REEDHYQNDKGIRLLDYRKLVPYLEQW 962
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1224-2037 8.34e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.69  E-value: 8.34e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1224 SEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKA 1303
Cdd:TIGR02169  186 IERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1304 ERENLLQTNRDLQFEKDTL-----RQGQEKLsasLEATLQVKQLLSTEAETLRTQLDcASKALRKAELDMRQLQTSNSSL 1378
Cdd:TIGR02169  266 RLEEIEQLLEELNKKIKDLgeeeqLRVKEKI---GELEAEIASLERSIAEKERELED-AEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1379 TKLLEEIKTCRAitdseciQLLHEKESLAASERTLLA----------------------------EKEELLSENRIITEK 1430
Cdd:TIGR02169  342 EREIEEERKRRD-------KLTEEYAELKEELEDLRAeleevdkefaetrdelkdyrekleklkrEINELKRELDRLQEE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1431 LSKQSEEVARLEM---GLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQ 1507
Cdd:TIGR02169  415 LQRLSEELADLNAaiaGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1508 EATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEA-------------QDAKKNLE--KEHTSMI 1572
Cdd:TIGR02169  495 AEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAagnrlnnvvveddAVAKEAIEllKRRKAGR 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1573 QAKDNLNaELKTCCCEKNMLLRDG-----LNLQEECQKLNEEIREI-QQTLILEKEARAKES---------ETSLYE--- 1634
Cdd:TIGR02169  575 ATFLPLN-KMRDERRDLSILSEDGvigfaVDLVEFDPKYEPAFKYVfGDTLVVEDIEAARRLmgkyrmvtlEGELFEksg 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1635 --------NNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDfa 1706
Cdd:TIGR02169  654 amtggsraPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQE-- 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1707 aLSKSKLELQELHSCLTKIlddlrlnhEVALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEK--LEESYFILQKEISQ 1784
Cdd:TIGR02169  732 -EEKLKERLEELEEDLSSL--------EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEArlSHSRIPEIQAELSK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1785 LAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKektetlasLEDTKQTNARLQ 1864
Cdd:TIGR02169  803 LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGK--------KEELEEELEELE 874

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1865 NELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLE 1944
Cdd:TIGR02169  875 AALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLE 954

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1945 EERSVLNNQLLEMKKSLPSNTLRESEFR---KDADEEKASLQKSISLTSALLtEKDAELEKLRNEVtVLRGENATAKSLH 2021
Cdd:TIGR02169  955 DVQAELQRVEEEIRALEPVNMLAIQEYEevlKRLDELKEKRAKLEEERKAIL-ERIEEYEKKKREV-FMEAFEAINENFN 1032

                          890
                   ....*....|....*.
gi 568937376  2022 SVVQTLESDKVKLELK 2037
Cdd:TIGR02169 1033 EIFAELSGGTGELILE 1048
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 832-1699 9.64e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.28  E-value: 9.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   832 QVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLT---DMEAKFKEKDDREDQLV 908
Cdd:TIGR00606  203 QEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSkimKLDNEIKALKSRKKQME 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   909 KAKEKLENDIAEIMKMSGDNSSQLTKMND-ELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEE 987
Cdd:TIGR00606  283 KDNSELELKMEKVFQGTDEQLNDLYHNHQrTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEH 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   988 EKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEA-----------NRDL 1056
Cdd:TIGR00606  363 IRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQadeirdekkglGRTI 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1057 MQDMEELKTQADKAKSLTYL---LTSAKKEIEVMSEELRglKSEKQLYAQEANA----LKLEKGSLLSKLIEVETKITLL 1129
Cdd:TIGR00606  443 ELKKEILEKKQEELKFVIKElqqLEGSSDRILELDQELR--KAERELSKAEKNSltetLKKEVKSLQNEKADLDRKLRKL 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1130 QEDQQKL----WSVNETLHLEKERVSEEKQVAEKRYQQEHR---------DRESLVAEREKLLKEINAAQEELLKMHMEN 1196
Cdd:TIGR00606  521 DQEMEQLnhhtTTRTQMEMLTKDKMDKDEQIRKIKSRHSDEltsllgyfpNKKQLEDWLHSKSKEINQTRDRLAKLNKEL 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1197 DSLEASK----VSMQVLIEELRFCKDKLMAM--SEKARAEKEHLEGQVKKLTAENLVL----------VKDKDDVIQKLQ 1260
Cdd:TIGR00606  601 ASLEQNKnhinNELESKEEQLSSYEDKLFDVcgSQDEESDLERLKEEIEKSSKQRAMLagatavysqfITQLTDENQSCC 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1261 SAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVK 1340
Cdd:TIGR00606  681 PVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDI 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1341 QLLSTEAETLRTQLDCASKALRKAELdmrqLQTSNSSLTKLLEEIKTCRAITDSECIQLlhEKESLAASERTLLAEKEEL 1420
Cdd:TIGR00606  761 QRLKNDIEEQETLLGTIMPEEESAKV----CLTDVTIMERFQMELKDVERKIAQQAAKL--QGSDLDRTVQQVNQEKQEK 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1421 LSENRIITEKLskqsEEVARLEMGLNEKITYLTSEkevaCQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGD 1500
Cdd:TIGR00606  835 QHELDTVVSKI----ELNRKLIQDQQEQIQHLKSK----TNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKD 906

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1501 LRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKE-NQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIqakDNLN 1579
Cdd:TIGR00606  907 AKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDiKEKVKNIHGYMKDIENKIQDGKDDYLKQKETEL---NTVN 983

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1580 AELKTCCCEKNMLLRDGLNLQE--ECQKLNEEIREIQQTL-ILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCS 1656
Cdd:TIGR00606  984 AQLEECEKHQEKINEDMRLMRQdiDTQKIQERWLQDNLTLrKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENI 1063

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*.
gi 568937376  1657 EQL-QTENFTLTQEKTNSEQKV--EEIIKEKELLSAETAQLAANIE 1699
Cdd:TIGR00606 1064 DLIkRNHVLALGRQKGYEKEIKhfKKELREPQFRDAEEKYREMMIV 1109
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1020-2097 1.08e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 1.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1020 ASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMeelKTQADKAKSLTYLLTSAKKEIEVMSEELRGlKSEKQ 1099
Cdd:pfam15921  128 AMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDS---NTQIEQLRKMMLSHEGVLQEIRSILVDFEE-ASGKK 203

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1100 LYAQEANALKLEK--GSLLSKLI-EVETKITLLQedqQKLWSVNETLhlekERVSEEKQVAEKRYQQEHRDR-ESLVAER 1175
Cdd:pfam15921  204 IYEHDSMSTMHFRslGSAISKILrELDTEISYLK---GRIFPVEDQL----EALKSESQNKIELLLQQHQDRiEQLISEH 276

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1176 EKllkEINAAQEELLKMHMENDSLEAskvsmqvlieelrfckdKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDV 1255
Cdd:pfam15921  277 EV---EITGLTEKASSARSQANSIQS-----------------QLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREA 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1256 IQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAErenLLQTNRDLQFEKD-TLRQGQEKLSASLE 1334
Cdd:pfam15921  337 KRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLAD---LHKREKELSLEKEqNKRLWDRDTGNSIT 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1335 ATLQVKQLLSTEAETLRtqLDCASKALR-----KAELDMRQLQTSNSSLTKLleeiktcraitDSECIQLLHEKESLAAS 1409
Cdd:pfam15921  414 IDHLRRELDDRNMEVQR--LEALLKAMKsecqgQMERQMAAIQGKNESLEKV-----------SSLTAQLESTKEMLRKV 480

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1410 ERTLLAEKEELLSENRIITEkLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLK---EKSALELQNGD 1486
Cdd:pfam15921  481 VEELTAKKMTLESSERTVSD-LTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNvqtECEALKLQMAE 559

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1487 LLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLlgnidalKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEK 1566
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQL-------EKEINDRRLELQEFKILKDKKDAKIRELEARVSDLEL 632

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1567 EHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIReiqqtlILEKEARAKESETSLyENNKLhgrvvlle 1646
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE------VLKRNFRNKSEEMET-TTNKL-------- 697

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1647 eEIQRLRVCSEQLQTENfTLTQEKTNSEQKVEEIIKEKELLSAETAQ---LAANIETLKSDFAALSKSKLELQELHSclt 1723
Cdd:pfam15921  698 -KMQLKSAQSELEQTRN-TLKSMEGSDGHAMKVAMGMQKQITAKRGQidaLQSKIQFLEEAMTNANKEKHFLKEEKN--- 772

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1724 kilddlrlnhevALTERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEEsyFILQKEISQLAQTNSHIsanllesQSEN 1803
Cdd:pfam15921  773 ------------KLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME--VALDKASLQFAECQDII-------QRQE 831

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1804 RTLRKDKSKLTLKIRELETlhsftAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQN---ELDTLKENNLKTVEE 1880
Cdd:pfam15921  832 QESVRLKLQHTLDVKELQG-----PGYTSNSSMKPRLLQPASFTRTHSNVPSSQSTASFLSHhsrKTNALKEDPTRDLKQ 906

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1881 LnkSKELLSVENQkmeefkkeietlkqaaaQKSQQLSALQEENVklAEELGRTRDEVTS---HQKLEEERSVLNNQLLEM 1957
Cdd:pfam15921  907 L--LQELRSVINE-----------------EPTVQLSKAEDKGR--APSLGALDDRVRDciiESSLRSDICHSSSNSLQT 965

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1958 KKSLPSNTLRESEFRKDADEekaslqksISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELK 2037
Cdd:pfam15921  966 EGSKSSETCSREPVLLHAGE--------LEDPSSCFTFPSTASPSVKNSASRSFHSSPKKSPVHSLLTSSAEGSIGSSSQ 1037

                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937376  2038 VKNlelqlkenKRQLSSSSGNTDAQAEEDERAQES----QQMIDFLNSVIVDLQRKNQDLKMKV 2097
Cdd:pfam15921 1038 YRS--------AKTIHSPDSVKDSQSLPIETTGKTcrklQNRLESLQTLVEDLQLKNQAMSSMI 1093
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1015-1588 1.12e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.07  E-value: 1.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1015 AKYEKASSETKTKHEEiLQNLQKMLADTE----DKLKAAQEANRDLMQDMEELKTQ-ADKAKSLTYLLTSAKKEIEVMSE 1089
Cdd:pfam12128  244 TKLQQEFNTLESAELR-LSHLHFGYKSDEtliaSRQEERQETSAELNQLLRTLDDQwKEKRDELNGELSAADAAVAKDRS 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1090 ELRGLKSEKQLYAQ---EANALKLEK-GSLLSKLIEVETKITLLQEDQQKLWSVNETLhlEKERVSEEKQVAEKRYQQEH 1165
Cdd:pfam12128  323 ELEALEDQHGAFLDadiETAAADQEQlPSWQSELENLEERLKALTGKHQDVTAKYNRR--RSKIKEQNNRDIAGIKDKLA 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1166 RDREslvaEREKLLKEINA---AQEELLKMHMENDSLEASKVSMQVL--IEELRFCKDKLMAMSE-------------KA 1227
Cdd:pfam12128  401 KIRE----ARDRQLAVAEDdlqALESELREQLEAGKLEFNEEEYRLKsrLGELKLRLNQATATPElllqlenfderieRA 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1228 RAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQE-----------IEDLTTEKKSAAEKQMSLDN 1296
Cdd:pfam12128  477 REEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELelqlfpqagtlLHFLRKEAPDWEQSIGKVIS 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1297 TCLTLK------------AERENLLQTNRDLQ--------FEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDC 1356
Cdd:pfam12128  557 PELLHRtdldpevwdgsvGGELNLYGVKLDLKridvpewaASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEK 636

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1357 ASK-------ALRKAELDMRQLQTSNSSLT-KLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRiiT 1428
Cdd:pfam12128  637 ASReetfartALKNARLDLRRLFDEKQSEKdKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREAR--T 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1429 EKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKyDQE 1508
Cdd:pfam12128  715 EKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVR-RQE 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1509 ATNRRIVMQEKMKLlgNIDALKKELQERKKENQELtssKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCE 1588
Cdd:pfam12128  794 VLRYFDWYQETWLQ--RRPRLATQLSNIERAISEL---QQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCE 868
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 777-983 1.87e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 1.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  777 ELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAV 856
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  857 SAQTRMQDTVNKLHQKEEQ----FNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQL 932
Cdd:COG4942   101 AQKEELAELLRALYRLGRQpplaLLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 568937376  933 TKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAAR 983
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
PTZ00121 PTZ00121
MAEBL; Provisional
 771-1581 1.93e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.61  E-value: 1.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  771 NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFAS 850
Cdd:PTZ00121 1055 NHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEAR 1134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  851 TSEEAVSAQ-TRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNS 929
Cdd:PTZ00121 1135 KAEDARKAEeARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKA 1214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  930 SQLTKMNDELRLKE-RSVEELQLK---LTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKME- 1004
Cdd:PTZ00121 1215 EEARKAEDAKKAEAvKKAEEAKKDaeeAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADe 1294

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1005 ----TSYNQCQDLKAKYEKA--SSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLT 1078
Cdd:PTZ00121 1295 akkaEEKKKADEAKKKAEEAkkADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE 1374

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1079 SAKKEIEVMSEelrglKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAE 1158
Cdd:PTZ00121 1375 EAKKKADAAKK-----KAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA 1449

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1159 KRYQQEHRDRESLV--AEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVL--IEELRFCKDKLMAMSEKARAEKEHL 1234
Cdd:PTZ00121 1450 KKKAEEAKKAEEAKkkAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAkkAAEAKKKADEAKKAEEAKKADEAKK 1529

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1235 EGQVKKLTAENLVLVKDKDDVIQKLqsayEELVKdqkalVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRD 1314
Cdd:PTZ00121 1530 AEEAKKADEAKKAEEKKKADELKKA----EELKK-----AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKL 1600

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1315 LQFEKdtlRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDS 1394
Cdd:PTZ00121 1601 YEEEK---KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA 1677

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1395 ECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDsll 1474
Cdd:PTZ00121 1678 EEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEE--- 1754

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1475 KEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKllgNIDALKKELQERKKENQE-LTSSKCDLSLL 1553
Cdd:PTZ00121 1755 EKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK---DIFDNFANIIEGGKEGNLvINDSKEMEDSA 1831

                         810       820
                  ....*....|....*....|....*...
gi 568937376 1554 LKEAQDAKKNLEKEHTSMIQAKDNLNAE 1581
Cdd:PTZ00121 1832 IKEVADSKNMQLEEADAFEKHKFNKNNE 1859
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
427-945 1.98e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 1.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  427 LNQLEEEKRKVEDLQFRVEE-ESITKGDLE-TQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRvatvSEKSRIMELE 504
Cdd:PRK02224  161 LGKLEEYRERASDARLGVERvLSDQRGSLDqLKAQIEEKEEKDLHERLNGLESELAELDEEIERYE----EQREQARETR 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  505 KDLALRAQEVAELRRRLESskppgdvdmslsLLQEISALQEKLEAIHTDhqgemtslkehfgarEEAFQKEIKALHTATE 584
Cdd:PRK02224  237 DEADEVLEEHEERREELET------------LEAEIEDLRETIAETERE---------------REELAEEVRDLRERLE 289

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  585 KLSKENESLRSKLDHANKEnSDVIALWKSKLETAIASHQQAMEELKVSFSkgigtdsaefaELKTQIERLRldyqHEIES 664
Cdd:PRK02224  290 ELEEERDDLLAEAGLDDAD-AEAVEARREELEDRDEELRDRLEECRVAAQ-----------AHNEEAESLR----EDADD 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  665 LQSKQDSERSAhAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhlveMEDTLNKLQEAEikvKELEVLQAKYTEQS 744
Cdd:PRK02224  354 LEERAEELREE-AAELESELEEAREAVEDRREEIEELEEEIEELRER----FGDAPVDLGNAE---DFLEELREERDELR 425

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  745 EVIGNFTSQLSAVKEKLLDLDALRKA-----------NSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSItKEL 813
Cdd:PRK02224  426 EREAELEATLRTARERVEEAEALLEAgkcpecgqpveGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDL 504

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  814 QEKElvltglqDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDM 893
Cdd:PRK02224  505 VEAE-------DRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAEL 577

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568937376  894 EAKFKEKDDREDQLVKAKEKLE--NDIAEIMKMSGDNSSQLTKMNDELR--LKERS 945
Cdd:PRK02224  578 NSKLAELKERIESLERIRTLLAaiADAEDEIERLREKREALAELNDERRerLAEKR 633
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1111-1855 3.07e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.66  E-value: 3.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1111 EKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELL 1190
Cdd:TIGR00618  164 EKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1191 KMHMENDSLEASKVSMQVLIEELRFCKDklmAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQ 1270
Cdd:TIGR00618  244 YLTQKREAQEEQLKKQQLLKQLRARIEE---LRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKM 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1271 KALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQF-----EKDTLRQGQEKLSASLEATLQVKQLLST 1345
Cdd:TIGR00618  321 RSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIreiscQQHTLTQHIHTLQQQKTTLTQKLQSLCK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1346 EAETLRTQLDCASkALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENR 1425
Cdd:TIGR00618  401 ELDILQREQATID-TRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKE 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1426 IITEKLSKQSEEVARLEMGLNEKityltsEKEVACQKVAKLKKQQDSLLKEKSALELQNGDllaDRESSIKTIGDLRRKY 1505
Cdd:TIGR00618  480 QIHLQETRKKAVVLARLLELQEE------PCPLCGSCIHPNPARQDIDNPGPLTRRMQRGE---QTYAQLETSEEDVYHQ 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1506 DQEATNRRIVMQEKMKLlgnidalkkELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKehtsmiqakdnlNAELKTC 1585
Cdd:TIGR00618  551 LTSERKQRASLKEQMQE---------IQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEK------------LSEAEDM 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1586 CCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVV--LLEEEIQRLRVCSEQLQTEN 1663
Cdd:TIGR00618  610 LACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIrvLPKELLASRQLALQKMQSEK 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1664 FTLTQEKtnseqkvEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEV 1743
Cdd:TIGR00618  690 EQLTYWK-------EMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEA 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1744 lQDNKNLLAEKREMMLRNEEALK-EKEKLEESYFILQKEISQL-AQTNSHISANLLESQSENRTLRKDKSKLTLKIREL- 1820
Cdd:TIGR00618  763 -HFNNNEEVTAALQTGAELSHLAaEIQFFNRLREEDTHLLKTLeAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKs 841

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 568937376  1821 ETLHSFTAAQTA-EDAMQIMEQMTKEKTETLASLED 1855
Cdd:TIGR00618  842 ATLGEITHQLLKyEECSKQLAQLTQEQAKIIQLSDK 877
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 428-980 4.22e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.94  E-value: 4.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   428 NQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKL------------------------- 482
Cdd:TIGR04523   47 NELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnsdlskinseikndkeqknklevel 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   483 ---QRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEAIHTDHqgemt 559
Cdd:TIGR04523  127 nklEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELE-----NELNLLEKEKLNIQKNIDKIKNKL----- 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   560 SLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSD---VIALWKSKLETAIASHQQAMEELK------ 630
Cdd:TIGR04523  197 LKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEkttEISNTQTQLNQLKDEQNKIKKQLSekqkel 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   631 VSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAED 710
Cdd:TIGR04523  277 EQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSES 356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   711 qhlvemeDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDalrKANSEGKLELETLRQQLEGAEK 790
Cdd:TIGR04523  357 -------ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQE---KLNQQKDEQIKKLQQEKELLEK 426

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   791 QIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKekfastseeavsaqtrmqdtvNKLH 870
Cdd:TIGR04523  427 EIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIK---------------------QNLE 485

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   871 QKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELR--LKERSVEE 948
Cdd:TIGR04523  486 QKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKkeNLEKEIDE 565

                          570       580       590
                   ....*....|....*....|....*....|..
gi 568937376   949 LQLKLTKANENASFLQKSIGEVTLKAEQSQQQ 980
Cdd:TIGR04523  566 KNKEIEELKQTQKSLKKKQEEKQELIDQKEKE 597
PRK11281 PRK11281
mechanosensitive channel MscK;
775-982 4.38e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.22  E-value: 4.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  775 KLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKeLVLTGLQDSLNQVNQvketlekELQTLKEKFASTSEE 854
Cdd:PRK11281   79 KEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLST-LSLRQLESRLAQTLD-------QLQNAQNDLAEYNSQ 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  855 AVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEndiaeimKMSGDNSSQLTk 934
Cdd:PRK11281  151 LVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQ-------RKSLEGNTQLQ- 222

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 568937376  935 mndELRLKERsvEELQLKLTKANENASFLQKSIGEVTLkaEQSQQQAA 982
Cdd:PRK11281  223 ---DLLQKQR--DYLTARIQRLEHQLQLLQEAINSKRL--TLSEKTVQ 263
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
700-921 4.57e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 4.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  700 AVKARLDSAEDQ--HLVEMEDTLNKLQEaeiKVKELEVLQAKYTEqsevignftsqLSAVKEKLLDLDALRKAnsegkLE 777
Cdd:COG4913   222 DTFEAADALVEHfdDLERAHEALEDARE---QIELLEPIRELAER-----------YAAARERLAELEYLRAA-----LR 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  778 LETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQV-NQVKETLEKELQTLKEKFastsEEAV 856
Cdd:COG4913   283 LWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLEREL----EERE 358

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568937376  857 SAQTRMQDTVNKLHQK----EEQFNVLSSELEKLRENLTDMEAKFKEK----DDREDQLVKAKEKLENDIAEI 921
Cdd:COG4913   359 RRRARLEALLAALGLPlpasAEEFAALRAEAAALLEALEEELEALEEAlaeaEAALRDLRRELRELEAEIASL 431
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1666-1918 5.16e-06

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 51.83  E-value: 5.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1666 LTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEvalTERAEVLQ 1745
Cdd:PLN02939  147 LNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIKLAAQEKIHVEILEEQLEKLRNELLIRGA---TEGLCVHS 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1746 DNKNLLAEKRE-MMLRNE-EALKEK----EKLEESYFILQKEISQLAQTNSHISANLLESQSenrtlrkDKSKL-TLKI- 1817
Cdd:PLN02939  224 LSKELDVLKEEnMLLKDDiQFLKAElievAETEERVFKLEKERSLLDASLRELESKFIVAQE-------DVSKLsPLQYd 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1818 ---RELETLHSF--TAAQTAEDAMQIMEQMT--KEKTETL-ASLEDTKQTnaRLQNELDTLKENNLKTVEE-LNKS-KEL 1887
Cdd:PLN02939  297 cwwEKVENLQDLldRATNQVEKAALVLDQNQdlRDKVDKLeASLKEANVS--KFSSYKVELLQQKLKLLEErLQASdHEI 374

                         250       260       270
                  ....*....|....*....|....*....|....
gi 568937376 1888 LS---VENQKMEEFKKEIETLKQAAAQKSQQLSA 1918
Cdd:PLN02939  375 HSyiqLYQESIKEFQDTLSKLKEESKKRSLEHPA 408
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 404-1380 5.56e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.97  E-value: 5.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   404 ELEAKMDQLRTMVEAADREKVELlNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQ 483
Cdd:TIGR00606  225 QITSKEAQLESSREIVKSYENEL-DPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   484 RELEDTRVATVSEKSR-IMELEKDLALRAQEvaelRRRLESSKPPGDVDMSLSLLQEiSALQEKLEAIHTDHQGEMTSLK 562
Cdd:TIGR00606  304 NDLYHNHQRTVREKEReLVDCQRELEKLNKE----RRLLNQEKTELLVEQGRLQLQA-DRHQEHIRARDSLIQSLATRLE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   563 EHFGAREEAFQKEIKALHTatekLSKENESLRSKLdhankensdvIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSA 642
Cdd:TIGR00606  379 LDGFERGPFSERQIKNFHT----LVIERQEDEAKT----------AAQLCADLQSKERLKQEQADEIRDEKKGLGRTIEL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   643 EFAELKTQIERLRldyqHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNK 722
Cdd:TIGR00606  445 KKEILEKKQEELK----FVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKL 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   723 LQEAEIKVKELEVLqakyteqsevignfTSQLSAVKEKLLDLDALRKANSEGKLELETlrqqLEGAEKQIKNLETERNAE 802
Cdd:TIGR00606  521 DQEMEQLNHHTTTR--------------TQMEMLTKDKMDKDEQIRKIKSRHSDELTS----LLGYFPNKKQLEDWLHSK 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   803 SSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKF--ASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLS 880
Cdd:TIGR00606  583 SKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdVCGSQDEESDLERLKEEIEKSSKQRAMLAGAT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   881 SELEKLRENLTDMEAKFKEKDDREdqlVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENA 960
Cdd:TIGR00606  663 AVYSQFITQLTDENQSCCPVCQRV---FQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSII 739

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   961 SFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKkmETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMla 1040
Cdd:TIGR00606  740 DLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPE--EESAKVCLTDVTIMERFQMELKDVERKIAQQAAKL-- 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1041 DTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEK-QLYAQEANALKLEKgsllskl 1119
Cdd:TIGR00606  816 QGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKlQIGTNLQRRQQFEE------- 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1120 iEVETKITLLQEdqqklwsVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSL 1199
Cdd:TIGR00606  889 -QLVELSTEVQS-------LIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDI 960

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1200 EAskvsmQVLIEELRFCKDKLMAMSeKARAEKEHLEGQVKKLTAENLVLVKDKDDviqklQSAYEELVKDQKALVQEIED 1279
Cdd:TIGR00606  961 EN-----KIQDGKDDYLKQKETELN-TVNAQLEECEKHQEKINEDMRLMRQDIDT-----QKIQERWLQDNLTLRKRENE 1029

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1280 LTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSAsleatlqvKQLLSTEAETLRTQLDCASK 1359
Cdd:TIGR00606 1030 LKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYE--------KEIKHFKKELREPQFRDAEE 1101

                          970       980
                   ....*....|....*....|.
gi 568937376  1360 ALRKAELDMRQLQTSNSSLTK 1380
Cdd:TIGR00606 1102 KYREMMIVMRTTELVNKDLDI 1122
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
335-594 5.79e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 5.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  335 LTETSSRYARKISGTTALQEALKEKQQHIEQLlAERDLERAEVAKATSHVGEIEQELALARDGHDQhVLELEAKMDQLRT 414
Cdd:COG4913   622 LEEELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVASAEREIAELEAELERLDASSDD-LAALEEQLEELEA 699

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  415 MVEAADREKVELLNQLEEEKRKVEDLQFRVEeesitkgdlETQTKLEHA-RTKELEQSLLFEKtkadKLQRELEDTRVAT 493
Cdd:COG4913   700 ELEELEEELDELKGEIGRLEKELEQAEEELD---------ELQDRLEAAeDLARLELRALLEE----RFAAALGDAVERE 766

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  494 VSEK--SRIMELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSL--LQEISALQEKLEAIH-TDHQGEMTSLKEHFGAR 568
Cdd:COG4913   767 LRENleERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLesLPEYLALLDRLEEDGlPEYEERFKELLNENSIE 846

                         250       260
                  ....*....|....*....|....*...
gi 568937376  569 E-EAFQKEIK-ALHTATEKLSKENESLR 594
Cdd:COG4913   847 FvADLLSKLRrAIREIKERIDPLNDSLK 874
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1593-2047 6.25e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 6.25e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1593 LRDGLN-LQEECQKLNEEIREIQQTLILEKEARAKESETsLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKT 1671
Cdd:PRK02224  204 LHERLNgLESELAELDEEIERYEEQREQARETRDEADEV-LEEHEERREELETLEAEIEDLRETIAETEREREELAEEVR 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1672 NSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQElhSCLTKILDDLRLNHEV-ALTERAEVLQD-NKN 1749
Cdd:PRK02224  283 DLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD--RLEECRVAAQAHNEEAeSLREDADDLEErAEE 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1750 LLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSfTAA 1829
Cdd:PRK02224  361 LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR-TAR 439

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1830 QTAEDAMQIMEQ-------MTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQ------KME 1896
Cdd:PRK02224  440 ERVEEAEALLEAgkcpecgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRierleeRRE 519

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1897 EFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTS-HQKLEEERSV---LNNQLLEMKKSLPS-NTLRES-E 1970
Cdd:PRK02224  520 DLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEaEEEAEEAREEvaeLNSKLAELKERIESlERIRTLlA 599

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937376 1971 FRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKslhsvVQTLESDKVKLELKVKNLELQLKE 2047
Cdd:PRK02224  600 AIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEAR-----IEEAREDKERAEEYLEQVEEKLDE 671
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 764-920 6.34e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.54  E-value: 6.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  764 LDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKE--TLEKEL 841
Cdd:COG1579    19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyeALQKEI 98

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937376  842 QTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLtdmEAKFKEKDDREDQLVKAKEKLENDIAE 920
Cdd:COG1579    99 ESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL---DEELAELEAELEELEAEREELAAKIPP 174
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1554-2055 6.97e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.56  E-value: 6.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1554 LKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTL------ILEKEARAKE 1627
Cdd:TIGR04523   49 LKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIkndkeqKNKLEVELNK 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1628 SETSLYENNKLHGRVVlleEEIQRLRVCSEQLQTENFTLTQEKTNSEqkveeiiKEKELLSAETAQLAANIETLKSDFAA 1707
Cdd:TIGR04523  129 LEKQKKENKKNIDKFL---TEIKKKEKELEKLNNKYNDLKKQKEELE-------NELNLLEKEKLNIQKNIDKIKNKLLK 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1708 LSKSKLELQ---ELHSCLTKILDDLRlNHEVALTERAEVLQDNKNllaEKREMMLRNEEALKE-KEKLEESYFILQKEIS 1783
Cdd:TIGR04523  199 LELLLSNLKkkiQKNKSLESQISELK-KQNNQLKDNIEKKQQEIN---EKTTEISNTQTQLNQlKDEQNKIKKQLSEKQK 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1784 QLAQTNSHIS---ANLLESQSENRTLRKDKSKLTLKireleTLHSFTAAQTAEdamqiMEQMTKEKTETLASLEDTKQTN 1860
Cdd:TIGR04523  275 ELEQNNKKIKeleKQLNQLKSEISDLNNQKEQDWNK-----ELKSELKNQEKK-----LEEIQNQISQNNKIISQLNEQI 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1861 ARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETL--------------KQAAAQKSQQLSALQEENVKL 1926
Cdd:TIGR04523  345 SQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLesqindleskiqnqEKLNQQKDEQIKKLQQEKELL 424

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1927 AEELGRTRDEVTSHQK----LEEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKASLQKsislTSALLTEKDAELEK 2002
Cdd:TIGR04523  425 EKEIERLKETIIKNNSeikdLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ----KQKELKSKEKELKK 500

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 568937376  2003 LRNEVTVLRGENATAK----SLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSS 2055
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTkkisSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKE 557
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1066-1290 7.36e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 7.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1066 QADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHL 1145
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1146 EKERVSEE-KQVAEKRYQQEHRDRESLV---------AEREKLLKEINAAQEELLkmhmenDSLEASKVSMQVLIEELRF 1215
Cdd:COG4942    98 ELEAQKEElAELLRALYRLGRQPPLALLlspedfldaVRRLQYLKYLAPARREQA------EELRADLAELAALRAELEA 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937376 1216 CKDKLMAMSEKARAEKEHLEgqvkKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEK 1290
Cdd:COG4942   172 ERAELEALLAELEEERAALE----ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
468-1059 8.12e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 8.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  468 LEQSLLFEKtkADKLQ---RELEDTRVATVSEKSRIMELE--KDLALRAQEVAELRRRLESSKPPGDVDMSLSLLQEISA 542
Cdd:COG4913   218 LEEPDTFEA--ADALVehfDDLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  543 LQEKLEAIHTDHQGEMTSLKehfgAREEAFQKEIKALHTATEKLSKEN-ESLRSKLDHANKEnsdvialwKSKLETAIAS 621
Cdd:COG4913   296 ELEELRAELARLEAELERLE----ARLDALREELDELEAQIRGNGGDRlEQLEREIERLERE--------LEERERRRAR 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  622 HQQAMEELKVSFSkgigTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKemetmqakLMKIIKEKEDSLEAV 701
Cdd:COG4913   364 LEALLAALGLPLP----ASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRD--------LRRELRELEAEIASL 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  702 KARlDSAEDQHLVEMEDTLNklQEAEIKVKEL----EVLQAKYTEQS-----E-VIGNFTSQLsAVKEKLLDlDALRKAN 771
Cdd:COG4913   432 ERR-KSNIPARLLALRDALA--EALGLDEAELpfvgELIEVRPEEERwrgaiErVLGGFALTL-LVPPEHYA-AALRWVN 506

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  772 SEgKLELetlRQQLEGAEKQIKNLETERnaesSKANSITKELQEKELVLTG-LQDSLNQVNQVK--ETLEkELQtlKEKF 848
Cdd:COG4913   507 RL-HLRG---RLVYERVRTGLPDPERPR----LDPDSLAGKLDFKPHPFRAwLEAELGRRFDYVcvDSPE-ELR--RHPR 575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  849 ASTseeaVSAQTRMQDTvnkLHQK----------------EEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKE 912
Cdd:COG4913   576 AIT----RAGQVKGNGT---RHEKddrrrirsryvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE 648

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  913 KLEN---------DIAEIMKMSGDNSSQLTKM---NDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQ 980
Cdd:COG4913   649 ALQRlaeyswdeiDVASAEREIAELEAELERLdasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEE 728

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568937376  981 AARKHEEEKKELEEKLLELEkkmetsynqcQDLKAKYEKASSETKTKheEILQNLQKMLADTEDKLKAAQEANRDLMQD 1059
Cdd:COG4913   729 LDELQDRLEAAEDLARLELR----------ALLEERFAAALGDAVER--ELRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 331-718 1.22e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   331 RTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKAtshvgeieqelalardghDQHVLELEAKMD 410
Cdd:TIGR02169  651 KSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI------------------ENRLDELSQELS 712

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   411 QLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTR 490
Cdd:TIGR02169  713 DASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR 792

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   491 VATVSEKSRIMElekdlalraQEVAELRRRLEsskppgDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREE 570
Cdd:TIGR02169  793 IPEIQAELSKLE---------EEVSRIEARLR------EIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE 857

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   571 AFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALwKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKtQ 650
Cdd:TIGR02169  858 NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ-LRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS-E 935

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   651 IERLRLDYQHEIESLQSKQD--SERSAHAKEMETMQAKLMKIIKEKEDsleaVKARLDSAEDQHLVEMED 718
Cdd:TIGR02169  936 IEDPKGEDEEIPEEELSLEDvqAELQRVEEEIRALEPVNMLAIQEYEE----VLKRLDELKEKRAKLEEE 1001
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1525-2050 1.28e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.67  E-value: 1.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1525 NIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCcceknmllrdgLNLQEECQ 1604
Cdd:PRK01156  184 NIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNEL-----------SSLEDMKN 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1605 KLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLqtENFTLTQEKTNSE-QKVEEIIKE 1683
Cdd:PRK01156  253 RYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDI--ENKKQILSNIDAEiNKYHAIIKK 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1684 KELLSAETAQLaaniETLKSDFAALSKSKLELQELHS----------CLTKILDDLRLNHEVALTERAEVLqdnKNLLAE 1753
Cdd:PRK01156  331 LSVLQKDYNDY----IKKKSRYDDLNNQILELEGYEMdynsylksieSLKKKIEEYSKNIERMSAFISEIL---KIQEID 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1754 KREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHIS--ANLLESQS------------ENRTLRK----DKSKLTL 1815
Cdd:PRK01156  404 PDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSrnMEMLNGQSvcpvcgttlgeeKSNHIINhyneKKSRLEE 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1816 KIRELETLHSfTAAQTAEDAMQIMEQMTKEKTETLAS----LEDTKQTNARLQNELDTLKENNLKTVEELNKSKEL-LSV 1890
Cdd:PRK01156  484 KIREIEIEVK-DIDEKIVDLKKRKEYLESEEINKSINeynkIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLkLED 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1891 ENQKMEEFKK--------EIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSH-QKLEEERSVLNNQ--LLEMKK 1959
Cdd:PRK01156  563 LDSKRTSWLNalavisliDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSiREIENEANNLNNKynEIQENK 642

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1960 SLPSNTLRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEvtvLRGENATAKSLHSVVQTLESDKVKLELKVK 2039
Cdd:PRK01156  643 ILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKA---LDDAKANRARLESTIEILRTRINELSDRIN 719

                         570
                  ....*....|.
gi 568937376 2040 NLELQLKENKR 2050
Cdd:PRK01156  720 DINETLESMKK 730
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 679-1479 1.42e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.56  E-value: 1.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   679 EMETMQAKLMKIIKEKEDSLEAVKARLDSAED---QHLVEMEDTLNKLQEAEIKVKELEVLQAKYteqsevignftsQLS 755
Cdd:pfam01576   58 EAEEMRARLAARKQELEEILHELESRLEEEEErsqQLQNEKKKMQQHIQDLEEQLDEEEAARQKL------------QLE 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   756 AV----KEKLLDLDALRKANSEGKLELEtlRQQLEgaeKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVN 831
Cdd:pfam01576  126 KVtteaKIKKLEEDILLLEDQNSKLSKE--RKLLE---ERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   832 QVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQfnvLSSELEKLRENLTDMEAKFKEKDDREDQLVKAK 911
Cdd:pfam01576  201 KGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEE---LQAALARLEEETAQKNNALKKIRELEAQISELQ 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   912 EKLENDIA---EIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEE 988
Cdd:pfam01576  278 EDLESERAarnKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQA 357

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   989 KKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKT-------------KHEEILQNLQKMLADTE-------DKLKA 1048
Cdd:pfam01576  358 LEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTlqqakqdsehkrkKLEGQLQELQARLSESErqraelaEKLSK 437

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1049 AQEANRDLMQDMEELKTQADK-AKSLTYLLTSAKKEIEVMSEELRglksEKQLYAQEANALKLEKGSLLSKLIEVETKit 1127
Cdd:pfam01576  438 LQSELESVSSLLNEAEGKNIKlSKDVSSLESQLQDTQELLQEETR----QKLNLSTRLRQLEDERNSLQEQLEEEEEA-- 511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1128 lLQEDQQKLWSVNETLHLEKERVSEEKQVAE------KRYQQE----HRDRESLVAEREKLLKEINAAQEELLKMHMEND 1197
Cdd:pfam01576  512 -KRNVERQLSTLQAQLSDMKKKLEEDAGTLEaleegkKRLQRElealTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLD 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1198 S-------LEASKVSMQVLIEELRFCKDKLMAMSEKARAE---------------------KEHLEGQVKKLTAENLVLV 1249
Cdd:pfam01576  591 HqrqlvsnLEKKQKKFDQMLAEEKAISARYAEERDRAEAEareketralslaraleealeaKEELERTNKQLRAEMEDLV 670

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1250 KDKDDV------IQKLQSAYEELVKDQKALVQEIEDlttEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLR 1323
Cdd:pfam01576  671 SSKDDVgknvheLERSKRALEQQVEEMKTQLEELED---ELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQL 747

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1324 QGQ-EKLSASLE-------ATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRA---IT 1392
Cdd:pfam01576  748 VKQvRELEAELEderkqraQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDeilAQ 827

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1393 DSEC--------IQLLHEKESLAASER---TLLAEKEELLSENRIITEKLSKQSEEVARLE---MGLNEKITYLTSEKEV 1458
Cdd:pfam01576  828 SKESekklknleAELLQLQEDLAASERarrQAQQERDELADEIASGASGKSALQDEKRRLEariAQLEEELEEEQSNTEL 907

                          890       900
                   ....*....|....*....|.
gi 568937376  1459 ACQKVAKLKKQQDSLLKEKSA 1479
Cdd:pfam01576  908 LNDRLRKSTLQVEQLTTELAA 928
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1410-2115 1.57e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.36  E-value: 1.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1410 ERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLA 1489
Cdd:pfam02463  172 KEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1490 DRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHT 1569
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1570 SMIQAKDNLNAELKTccCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLhgrvvLLEEEI 1649
Cdd:pfam02463  332 KEKEEIEELEKELKE--LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-----LKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1650 QRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKS---------KLELQELHS 1720
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELElkksedllkETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1721 CLTKILDDLRLNHEVALTERAE--------------------------------------------VLQDNKNLLAEKRE 1756
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARsglkvllalikdgvggriisahgrlgdlgvavenykvaistaviVEVSATADEVEERQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1757 MMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAM 1836
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAK 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1837 QIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQL 1916
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLA 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1917 SALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKASLQKSISLTSALLTEK 1996
Cdd:pfam02463  725 DRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1997 DAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQQMI 2076
Cdd:pfam02463  805 ALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKL 884

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 568937376  2077 DFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSY 2115
Cdd:pfam02463  885 KDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 823-1074 1.70e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  823 LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDD 902
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  903 REDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMndeLRLKERSVEELQLKLTKanenasfLQKSIGEVTLKAEQSQQQAA 982
Cdd:COG4942   105 ELAELLRALYRLGRQPPLALLLSPEDFLDAVRR---LQYLKYLAPARREQAEE-------LRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  983 RKheeekkeleekllelekkmETSYNQCQDLKAKYEKAssetKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEE 1062
Cdd:COG4942   175 EL-------------------EALLAELEEERAALEAL----KAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                         250
                  ....*....|..
gi 568937376 1063 LKTQADKAKSLT 1074
Cdd:COG4942   232 LEAEAAAAAERT 243
PRK11281 PRK11281
mechanosensitive channel MscK;
1859-2083 2.27e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 49.91  E-value: 2.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1859 TNARLQNELDTLKENNLKTVEE------LNKSKELLsvenQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELG- 1931
Cdd:PRK11281   37 TEADVQAQLDALNKQKLLEAEDklvqqdLEQTLALL----DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDe 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1932 --RTRDEVTSHQKLEEERSVLNNQLLEMKKSLpsntlresefrKDADEEKASLQKSISLTSALLTEKDAELEKLRNEvtv 2009
Cdd:PRK11281  113 etRETLSTLSLRQLESRLAQTLDQLQNAQNDL-----------AEYNSQLVSLQTQPERAQAALYANSQRLQQIRNL--- 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376 2010 LRGENATAKSLHSvvqtleSDKVKLELKVKNLELQLKENKRQLSSSSGNTD-AQAEED---ERAQESQQMIDFLNSVI 2083
Cdd:PRK11281  179 LKGGKVGGKALRP------SQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDlLQKQRDyltARIQRLEHQLQLLQEAI 250
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1725-2065 2.35e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 2.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1725 ILDDLRLNHEVALTERAEVLQdNKNLLAEKREmmLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENR 1804
Cdd:TIGR02169  192 IIDEKRQQLERLRREREKAER-YQALLKEKRE--YEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1805 TLRKDKSKLTLKIRELetlhsftaaqTAEDAMQIMEQMTkektETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKS 1884
Cdd:TIGR02169  269 EIEQLLEELNKKIKDL----------GEEEQLRVKEKIG----ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1885 KELLSVENQKMEEFKKEIETLKQAAAQKSQQLSAL----QEENVKLAEELGRTRDEVTSHQKLEEERsvlnNQLLEMKKS 1960
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLraelEEVDKEFAETRDELKDYREKLEKLKREI----NELKRELDR 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1961 LPSNTLRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTlESDKVKLELKVKN 2040
Cdd:TIGR02169  411 LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKE-EYDRVEKELSKLQ 489

                          330       340
                   ....*....|....*....|....*
gi 568937376  2041 LELQLKENKRQLSSSSGNTDAQAEE 2065
Cdd:TIGR02169  490 RELAEAEAQARASEERVRGGRAVEE 514
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 724-1225 2.90e-05

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 49.36  E-value: 2.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   724 QEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAES 803
Cdd:pfam07111   63 QQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGSQREL 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   804 SKANSITKElqEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSEL 883
Cdd:pfam07111  143 EEIQRLHQE--QLSSLTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLV 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   884 EKLRENLTDM---EAKFKEKDDREDQLVKAKEKLENDIAEI---MKMSGDNSSQLTKM----NDELRLKERSVEELQLKL 953
Cdd:pfam07111  221 ESLRKYVGEQvppEVHSQTWELERQELLDTMQHLQEDRADLqatVELLQVRVQSLTHMlalqEEELTRKIQPSDSLEPEF 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   954 TKANEN--ASFLQKSIG-EVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQC-QDLKAKYEKASSETKT--- 1026
Cdd:pfam07111  301 PKKCRSllNRWREKVFAlMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQEQAILQRAlQDKAAEVEVERMSAKGlqm 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1027 ---KHEEILQNLQKMLADTEDKLK----AAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVmseeLRGLKSEKQ 1099
Cdd:pfam07111  381 elsRAQEARRRQQQQTASAEEQLKfvvnAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVHT----IKGLMARKV 456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1100 LYAQeanaLKLEKGSLLSKLIEVETKITLLQEDqqklwsvnetLHLEKERVSEEKQVAEKRYQQE-HRDRESLVAEREKL 1178
Cdd:pfam07111  457 ALAQ----LRQESCPPPPPAPPVDADLSLELEQ----------LREERNRLDAELQLSAHLIQQEvGRAREQGEAERQQL 522

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568937376  1179 LK-------EINAAQEELLKMHMEndsLEASKVSMQVLIEELRFCKDKLMAMSE 1225
Cdd:pfam07111  523 SEvaqqleqELQRAQESLASVGQQ---LEVARQGQQESTEEAASLRQELTQQQE 573
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 806-1387 3.74e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.86  E-value: 3.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   806 ANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEK 885
Cdd:TIGR04523   28 ANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSK 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   886 LRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQK 965
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   966 SIGEVTLKAEQSQQ-----QAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLA 1040
Cdd:TIGR04523  188 NIDKIKNKLLKLELllsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1041 DTEDKLKAAQEANRDLMQDMEELKT------------QADKAKSLTYLLTSAKKEIEVMSEELRG-------LKSEKQLY 1101
Cdd:TIGR04523  268 QLSEKQKELEQNNKKIKELEKQLNQlkseisdlnnqkEQDWNKELKSELKNQEKKLEEIQNQISQnnkiisqLNEQISQL 347

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1102 AQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKE 1181
Cdd:TIGR04523  348 KKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1182 INAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKD----KLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQ 1257
Cdd:TIGR04523  428 IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTREsletQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKE 507

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1258 kLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAE--RENLLQTNRDLQFEKDTLRQGQEKLSASLEA 1335
Cdd:TIGR04523  508 -LEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFElkKENLEKEIDEKNKEIEELKQTQKSLKKKQEE 586

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937376  1336 TLQVKQLLSTE--------------AETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKT 1387
Cdd:TIGR04523  587 KQELIDQKEKEkkdlikeieekekkISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKE 652
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 344-629 3.85e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.28  E-value: 3.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   344 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAkatshvgEIEQELALARDGHDQHVLELEAKMDQLRTMVEAA---- 419
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELE-------AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLkeel 798

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   420 ---DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLF-------EKTKADKLQRELEDT 489
Cdd:TIGR02168  799 kalREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESlaaeieeLEELIEELESELEAL 878

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   490 RVATVSEKSRIMELEKDLALRAQEVAELRRRL--------ESSKPPGDVDMSLS-LLQEISALQEKLEAIHTDHQGEMTS 560
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRselrreleELREKLAQLELRLEgLEVRIDNLQERLSEEYSLTLEEAEA 958

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937376   561 LKEHFGAREEAFQKEIKALHTATEKLSKEN-------ESLRSKLDHANKENSDvialwkskLETAIASHQQAMEEL 629
Cdd:TIGR02168  959 LENKIEDDEEEARRRLKRLENKIKELGPVNlaaieeyEELKERYDFLTAQKED--------LTEAKETLEEAIEEI 1026
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1739-1932 3.94e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 3.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1739 ERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIR 1818
Cdd:COG4942    28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1819 E-------------LETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSK 1885
Cdd:COG4942   108 EllralyrlgrqppLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER 187

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 568937376 1886 ELLSvenQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGR 1932
Cdd:COG4942   188 AALE---ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 590-1907 4.57e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 48.89  E-value: 4.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   590 NESLRSKLDHANKENSDVIALWKsKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQ---IERLRLDYQHEIESLQ 666
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWK-KLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEiiyINKLKLELKEKIKNIS 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   667 SKQDSERSAhakemetmqAKLMKIIKEKEDSLEAVkARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSev 746
Cdd:TIGR01612  614 DKNEYIKKA---------IDLKKIIENNNAYIDEL-AKISPYQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYNELS-- 681

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   747 ignftsqlSAVKEKLLDldalrkaNSEGKLELETLRQQLEGAEKQIKNLETE------RNAESSKANSITKELQEKELVL 820
Cdd:TIGR01612  682 --------SIVKENAID-------NTEDKAKLDDLKSKIDKEYDKIQNMETAtvelhlSNIENKKNELLDIIVEIKKHIH 746

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   821 TGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNklhQKEEQFNVLSSELEKLRENLTDMEAKFKEK 900
Cdd:TIGR01612  747 GEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKN---HYNDQINIDNIKDEDAKQNYDKSKEYIKTI 823

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   901 DDREDQLVKAKEKLENDIAEIMK-----MSGDNS---------SQLTKMNDELRlKERSVEELQLKLTKANENASFLQ-- 964
Cdd:TIGR01612  824 SIKEDEIFKIINEMKFMKDDFLNkvdkfINFENNckekidsehEQFAELTNKIK-AEISDDKLNDYEKKFNDSKSLINei 902

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   965 -KSIGEV------------TLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEI 1031
Cdd:TIGR01612  903 nKSIEEEyqnintlkkvdeYIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKA 982

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1032 LQNLQkmLADTEDKlkaaqeaNRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEanalkle 1111
Cdd:TIGR01612  983 FKDAS--LNDYEAK-------NNELIKYFNDLKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIE------- 1046

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1112 kgsllsklIEVETKITLLQEDQQKLWSVN-ETLHLE--KERVSEEKQVAEKRYQQEHRDRESLVAERE-KLLKEINAAQE 1187
Cdd:TIGR01612 1047 --------IAIHTSIYNIIDEIEKEIGKNiELLNKEilEEAEINITNFNEIKEKLKHYNFDDFGKEENiKYADEINKIKD 1118

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1188 ELLKMHMEND----SLEASKVSMQVLIEELRFCKDKLMAMSEKArAEKEHLEGQVKKLtaENLVLVKDKD----DVIQKL 1259
Cdd:TIGR01612 1119 DIKNLDQKIDhhikALEEIKKKSENYIDEIKAQINDLEDVADKA-ISNDDPEEIEKKI--ENIVTKIDKKkniyDEIKKL 1195

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1260 QSAYEELVKDQ------------------------------------KALVQEIEDLTTEKKSAAEKQMSLdNTCLTLKA 1303
Cdd:TIGR01612 1196 LNEIAEIEKDKtsleevkginlsygknlgklflekideekkksehmiKAMEAYIEDLDEIKEKSPEIENEM-GIEMDIKA 1274

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1304 ERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAEtlrtqLDCASKALRKAELDMrqlQTSNSSLTKLLE 1383
Cdd:TIGR01612 1275 EMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIEDFSEESD-----INDIKKELQKNLLDA---QKHNSDINLYLN 1346

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1384 EIKTCRAITDSECIQLLHE--KESLAASERTLLAEKEELLSenriiTEKLSKQSEEVARLEMgLNEKITYLTSEKEVAcQ 1461
Cdd:TIGR01612 1347 EIANIYNILKLNKIKKIIDevKEYTKEIEENNKNIKDELDK-----SEKLIKKIKDDINLEE-CKSKIESTLDDKDID-E 1419

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1462 KVAKLKKQQDSLLKEKSalelQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQ-EKMKLLGNIDALKKELQERKKEn 1540
Cdd:TIGR01612 1420 CIKKIKELKNHILSEES----NIDTYFKNADENNENVLLLFKNIEMADNKSQHILKiKKDNATNDHDFNINELKEHIDK- 1494

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1541 qeltSSKCDlslllKEAQDAKKNLEKEHTSMIQAKDNLNAELKTcccEKNMLLRDGLN-LQEECQKLNEEIREIQQTLIL 1619
Cdd:TIGR01612 1495 ----SKGCK-----DEADKNAKAIEKNKELFEQYKKDVTELLNK---YSALAIKNKFAkTKKDSEIIIKEIKDAHKKFIL 1562

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1620 ekearakESETSLYENNKLHGRVVLLEEEIQRLRVCSE-----QLQTENFTLTQEK-TNSEQKVEEIIKEKELLSAETAQ 1693
Cdd:TIGR01612 1563 -------EAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKaaidiQLSLENFENKFLKiSDIKKKINDCLKETESIEKKISS 1635

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1694 LAAN-------------------IETLKSDFAALSKSKLELQELHSCLTKILDDL---RLNHEVALTERAevlqdnknll 1751
Cdd:TIGR01612 1636 FSIDsqdtelkengdnlnslqefLESLKDQKKNIEDKKKELDELDSEIEKIEIDVdqhKKNYEIGIIEKI---------- 1705

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1752 aekremmlrNEEALKEKEKLEESYFILQKEISQLAqtnSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAqt 1831
Cdd:TIGR01612 1706 ---------KEIAIANKEEIESIKELIEPTIENLI---SSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAG-- 1771

                         1370      1380      1390      1400      1410      1420      1430
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937376  1832 aedamqIMEQMTKEKTetlaSLEDTKQTNARLQNELdtlkennLKTVEELNKSKELLsvENQKMEEFKKEIETLKQ 1907
Cdd:TIGR01612 1772 ------CLETVSKEPI----TYDEIKNTRINAQNEF-------LKIIEIEKKSKSYL--DDIEAKEFDRIINHFKK 1828
PTZ00121 PTZ00121
MAEBL; Provisional
 1602-2104 9.00e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 9.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1602 ECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQ--KVEE 1679
Cdd:PTZ00121 1221 EDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEakKAEE 1300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1680 IIKEKELlsAETAQLAANIETLKSDfAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMML 1759
Cdd:PTZ00121 1301 KKKADEA--KKKAEEAKKADEAKKK-AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAK 1377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1760 RNEEALKEKEKLEESYFILQKEISQLAQTNSHI---------SANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQ 1830
Cdd:PTZ00121 1378 KKADAAKKKAEEKKKADEAKKKAEEDKKKADELkkaaaakkkADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK 1457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1831 TAEDAMQIMEQM-----TKEKTETLASLEDTKQTNARLQNELDTLKE--------NNLKTVEELNKSKELLSVEN-QKME 1896
Cdd:PTZ00121 1458 KAEEAKKKAEEAkkadeAKKKAEEAKKADEAKKKAEEAKKKADEAKKaaeakkkaDEAKKAEEAKKADEAKKAEEaKKAD 1537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1897 EFKKEIETLKQAAAQKSQQLSalQEENVKLAEELGRT-RDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESEFRKDA 1975
Cdd:PTZ00121 1538 EAKKAEEKKKADELKKAEELK--KAEEKKKAEEAKKAeEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA 1615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1976 DEEKAslqKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSS 2055
Cdd:PTZ00121 1616 EEAKI---KAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 568937376 2056 SgnTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAA 2104
Cdd:PTZ00121 1693 A--LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA 1739
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 334-920 9.34e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.86  E-value: 9.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   334 LLTETSSRYARKISGTTALQEALKEKQQHIEQLlaERDLERAEVAKATSHVGEIEQELALARdgHDQHVLELEAKMDQLR 413
Cdd:pfam01576   76 ILHELESRLEEEEERSQQLQNEKKKMQQHIQDL--EEQLDEEEAARQKLQLEKVTTEAKIKK--LEEDILLLEDQNSKLS 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   414 TMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSllfektkADKLQRELEDTRVAT 493
Cdd:pfam01576  152 KERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKA-------KRKLEGESTDLQEQI 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   494 VSEKSRIMELEKDLALRAQEVAELRRRLEsskppgdvdmslsllqEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQ 573
Cdd:pfam01576  225 AELQAQIAELRAQLAKKEEELQAALARLE----------------EETAQKNNALKKIRELEAQISELQEDLESERAARN 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   574 KEIKALHTATEKLSKENESLRSKLDHANKENSdvialWKSKLETAIASHQQAMEELKVSFSKGIG----TDSAEFAELKT 649
Cdd:pfam01576  289 KAEKQRRDLGEELEALKTELEDTLDTTAAQQE-----LRSKREQEVTELKKALEEETRSHEAQLQemrqKHTQALEELTE 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   650 QIERLRlDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKI---IKEKEDSLEAVKARLDSAEDQHlVEMEDTLNKLQea 726
Cdd:pfam01576  364 QLEQAK-RNKANLEKAKQALESENAELQAELRTLQQAKQDSehkRKKLEGQLQELQARLSESERQR-AELAEKLSKLQ-- 439

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   727 eikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLE----GAEKQIKNLETERNAE 802
Cdd:pfam01576  440 ----SELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEdernSLQEQLEEEEEAKRNV 515

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   803 SSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFastsEEAVSAQTRMQDTVNKLHQKEEQfnvLSSE 882
Cdd:pfam01576  516 ERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQL----EEKAAAYDKLEKTKNRLQQELDD---LLVD 588

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 568937376   883 LEKLRENLTDMEAKFKEKDD--REDQLVKAKEKLENDIAE 920
Cdd:pfam01576  589 LDHQRQLVSNLEKKQKKFDQmlAEEKAISARYAEERDRAE 628
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1753-2012 1.54e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1753 EKREMMLRNEEALKEKEKLEESYFILQKEISQLAQtnshisanLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTA 1832
Cdd:COG4913   219 EEPDTFEAADALVEHFDDLERAHEALEDAREQIEL--------LEPIRELAERYAAARERLAELEYLRAALRLWFAQRRL 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1833 EDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKEnnlktveelnkskELLSVENQKMEEFKKEIETLKQAAAQK 1912
Cdd:COG4913   291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEA-------------QIRGNGGDRLEQLEREIERLERELEER 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1913 SQQLSALQEenvkLAEELGrtrdevtshQKLEEERSVLNNQLLEMKkslpsntlresEFRKDADEEKASLQKSISLTSAL 1992
Cdd:COG4913   358 ERRRARLEA----LLAALG---------LPLPASAEEFAALRAEAA-----------ALLEALEEELEALEEALAEAEAA 413

                         250       260
                  ....*....|....*....|
gi 568937376 1993 LTEKDAELEKLRNEVTVLRG 2012
Cdd:COG4913   414 LRDLRRELRELEAEIASLER 433
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
354-801 1.55e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  354 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHvlELEAKMDQLRTMVEAADREKVELLNQLEEE 433
Cdd:COG4717    81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL--PLYQELEALEAELAELPERLEELEERLEEL 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  434 KRKVEDLQFRVEEesitkgdletQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRvatvsekSRIMELEKDLALRAQE 513
Cdd:COG4717   159 RELEEELEELEAE----------LAELQEELEELLEQLSLATEEELQDLAEELEELQ-------QRLAELEEELEEAQEE 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  514 VAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEAIHTdHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESL 593
Cdd:COG4717   222 LEELEEELEQLENELEAAALEERLKEARLLLLIAAALLA-LLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  594 RSKLDHANKEnsDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEiESLQSKQDSER 673
Cdd:COG4717   301 GKEAEELQAL--PALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE-ELEQEIAALLA 377

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  674 SAHAKEMETMQAKLMKiiKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKvKELEVLQAKYTEQSEVIGNFTSQ 753
Cdd:COG4717   378 EAGVEDEEELRAALEQ--AEEYQELKEELEELEEQLEELLGELEELLEALDEEELE-EELEELEEELEELEEELEELREE 454

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 568937376  754 LSAVKEKLLDLdalrkansEGKLELETLRQQLEGAEKQIKNLETERNA 801
Cdd:COG4717   455 LAELEAELEQL--------EEDGELAELLQELEELKAELRELAEEWAA 494
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1146-1365 1.65e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1146 EKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRfckdklmamsE 1225
Cdd:COG4942    28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR----------A 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1226 KARAEKEHLEGQVKKL----TAENLVLVKDKDDVIQKLQSA--YEELVKDQKalvQEIEDLTTEKKSAAEKQMSLDNTCL 1299
Cdd:COG4942    98 ELEAQKEELAELLRALyrlgRQPPLALLLSPEDFLDAVRRLqyLKYLAPARR---EQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937376 1300 TLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAE 1365
Cdd:COG4942   175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 481-944 1.81e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 1.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  481 KLQRELEDTRVATVSEKSRIMELEKDLAlraqEVAELRRRLESskppgDVDMS---LSLLQEISALQEKLEAIHTDhQGE 557
Cdd:COG3096   289 ELRRELFGARRQLAEEQYRLVEMARELE----ELSARESDLEQ-----DYQAAsdhLNLVQTALRQQEKIERYQED-LEE 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  558 MTS-LKEHFGAREEAfQKEIKALHTATEKLSKENESLRSKLdhankensdvialwkskletaiASHQQAMEELkvsfskg 636
Cdd:COG3096   359 LTErLEEQEEVVEEA-AEQLAEAEARLEAAEEEVDSLKSQL----------------------ADYQQALDVQ------- 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  637 igtdsaefaelktqiERLRLDYQheiESLQSKQDSERSAHAKEMETMQAklmkiikekEDSLEAVKARLDSAeDQHLVEM 716
Cdd:COG3096   409 ---------------QTRAIQYQ---QAVQALEKARALCGLPDLTPENA---------EDYLAAFRAKEQQA-TEEVLEL 460

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  717 EDTLNKLQEAEI---KVKELEVLQAKYTEQSEVIGNFTSQLSAVKEklLDLDALRKANSEGKL-ELETLRQQLEGAEKQI 792
Cdd:COG3096   461 EQKLSVADAARRqfeKAYELVCKIAGEVERSQAWQTARELLRRYRS--QQALAQRLQQLRAQLaELEQRLRQQQNAERLL 538

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  793 KNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEA---VSAQTRMQDTVNKL 869
Cdd:COG3096   539 EEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARApawLAAQDALERLREQS 618

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937376  870 HQKEEQFNVLSSELEKLRENLTDMEAKfkekddrEDQLVKAKEKLENDIAEIMKMSGDNSSQLtkmndeLRLKER 944
Cdd:COG3096   619 GEALADSQEVTAAMQQLLEREREATVE-------RDELAARKQALESQIERLSQPGGAEDPRL------LALAER 680
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2129-2146 1.90e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.90e-04
                           10
                   ....*....|....*...
gi 568937376  2129 RLFCDICDCFDlHDTEDC 2146
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1646-2013 2.37e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 2.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1646 EEEIQRLRVCSEQLQTENFTLTQEKtnsEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKI 1725
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRRER---EKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1726 LDDLRLNHEVALTERAEVlqdnknllaEKREMMLRNEEALKEKEKLEESYfilqkeiSQLAQTNSHISANLLESQSENRT 1805
Cdd:TIGR02169  260 ISELEKRLEEIEQLLEEL---------NKKIKDLGEEEQLRVKEKIGELE-------AEIASLERSIAEKERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1806 LRKDKSKLTLKIRELETLHsftaaqtaedamQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSK 1885
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELE------------REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1886 EllsvenqKMEEFKKEIETLKQaaaqksqQLSALQEENVKLAEELGRTRDEVTS----HQKLEEERSVLNNQLLEMKKSL 1961
Cdd:TIGR02169  392 E-------KLEKLKREINELKR-------ELDRLQEELQRLSEELADLNAAIAGieakINELEEEKEDKALEIKKQEWKL 457

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 568937376  1962 PSNtlreSEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGE 2013
Cdd:TIGR02169  458 EQL----AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 573-1252 2.50e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 46.25  E-value: 2.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   573 QKEIKALHTATEKLSKENESLRSKLDHANKENSDVIA------LWKSKLETAIAS----------HQQAMEELKVSFSKG 636
Cdd:pfam05483  112 RKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKennatrHLCNLLKETCARsaektkkyeyEREETRQVYMDLNNN 191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   637 IGTDSAEFAELKTQIERLRLDYQHEIeslqsKQDSERSAHAKEmetmqaKLMKIIKEKEDSLEAVKARLDSAEDQhlveM 716
Cdd:pfam05483  192 IEKMILAFEELRVQAENARLEMHFKL-----KEDHEKIQHLEE------EYKKEINDKEKQVSLLLIQITEKENK----M 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   717 EDTLNKLQEAEIKVKELEvlqAKYTEQSEVIGNFTSQLSAVKEKLLDLD-ALRKANSEGKleleTLRQQLEGAEKQIKNL 795
Cdd:pfam05483  257 KDLTFLLEESRDKANQLE---EKTKLQDENLKELIEKKDHLTKELEDIKmSLQRSMSTQK----ALEEDLQIATKTICQL 329

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   796 ETERNAESSKANsitKELQEKELVLTGLQDSLNqvnqvkeTLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQ 875
Cdd:pfam05483  330 TEEKEAQMEELN---KAKAAHSFVVTEFEATTC-------SLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKF 399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   876 FNVLSSELEKLRENLTDMEAKFKEKDDRE---DQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLK 952
Cdd:pfam05483  400 KNNKEVELEELKKILAEDEKLLDEKKQFEkiaEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTE 479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   953 LTKANENASFLQKSIGEVTLKAEQSQQQAArKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEIL 1032
Cdd:pfam05483  480 LEKEKLKNIELTAHCDKLLLENKELTQEAS-DMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFI 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1033 QNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSE-----KQLYAQE--A 1105
Cdd:pfam05483  559 QKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKgsaenKQLNAYEikV 638

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1106 NALKLEKGSLLSKLIEV----ETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKE 1181
Cdd:pfam05483  639 NKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDK 718

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937376  1182 INAAQEELLKMHMENDSLEAS-KVSMQVlieELRFCKDKLMAMSEKARAEKEHLEgQVKKLTAENLVLVKDK 1252
Cdd:pfam05483  719 IIEERDSELGLYKNKEQEQSSaKAALEI---ELSNIKAELLSLKKQLEIEKEEKE-KLKMEAKENTAILKDK 786
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1762-1945 2.72e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 2.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1762 EEALKEKEKLEESYFILQKEISQLAQtnshisanllesqsENRTLRKDKSKLTLKIRELETLHsftAAQTAEDAMQIMEQ 1841
Cdd:COG4717    77 EEELKEAEEKEEEYAELQEELEELEE--------------ELEELEAELEELREELEKLEKLL---QLLPLYQELEALEA 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1842 MTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQK-MEEFKKEIETLKQAAAQKSQQLSALQ 1920
Cdd:COG4717   140 ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEeLQDLAEELEELQQRLAELEEELEEAQ 219

                         170       180
                  ....*....|....*....|....*
gi 568937376 1921 EENVKLAEELGRTRDEVTSHQKLEE 1945
Cdd:COG4717   220 EELEELEEELEQLENELEAAALEER 244
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1598-2004 2.75e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.04  E-value: 2.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1598 NLQEECQKlneEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKV 1677
Cdd:pfam07888   34 NRLEECLQ---ERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1678 EEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQelhscltkilddlrlnhevalTERAEVLQDNKNLLAEKREm 1757
Cdd:pfam07888  111 EELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERE---------------------TELERMKERAKKAGAQRKE- 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1758 mlrnEEAlkEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKireLETLHSFTAAqtaedamq 1837
Cdd:pfam07888  169 ----EEA--ERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQK---LTTAHRKEAE-------- 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1838 iMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSK-ELLSVENQKMEEFKKeietLKQAAAQKSQQL 1916
Cdd:pfam07888  232 -NEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARlQAAQLTLQLADASLA----LREGRARWAQER 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1917 SALQEENVKLAEELGRTRDEVTSHQK-LEEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKASLQKSISLTSALLTE 1995
Cdd:pfam07888  307 ETLQQSAEADKDRIEKLSAELQRLEErLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAE 386


                   ....*....
gi 568937376  1996 KDAELEKLR 2004
Cdd:pfam07888  387 KQELLEYIR 395
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 347-603 3.96e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  347 SGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlardghdqhvlELEAKMDQLRTMVEAADREKVEL 426
Cdd:COG4942    13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-----------ALERRIAALARRIRALEQELAAL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  427 LNQLEEEKRKVEDLQFRVEEEsitKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKD 506
Cdd:COG4942    82 EAELAELEKEIAELRAELEAQ---KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  507 LalraQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKehfgAREEAFQKEIKALHTATEKL 586
Cdd:COG4942   159 L----AELAALRAELEAER-----AELEALLAELEEERAALEALKAERQKLLARLE----KELAELAAELAELQQEAEEL 225

                         250
                  ....*....|....*..
gi 568937376  587 SKENESLRSKLDHANKE 603
Cdd:COG4942   226 EALIARLEAEAAAAAER 242
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1256-1719 4.26e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 4.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1256 IQKLQSAYEELVKDQ----KALVQEIEDLTTEKKSAAEKQmsldntcltlkAERENLLQTNRDLQFEKDTLRQGQEKLSA 1331
Cdd:COG4717    48 LERLEKEADELFKPQgrkpELNLKELKELEEELKEAEEKE-----------EEYAELQEELEELEEELEELEAELEELRE 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1332 SLEATLQVKQLLST--EAETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKEslaAS 1409
Cdd:COG4717   117 ELEKLEKLLQLLPLyqELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EE 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1410 ERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYLTSEKEVAcQKVAKLKKQQDSLLKEKSALELQ-NGDLL 1488
Cdd:COG4717   194 LQDLAEELEELQQRLAELEEELEEAQEELEELE----EELEQLENELEAA-ALEERLKEARLLLLIAAALLALLgLGGSL 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1489 ADRESSIKTIGDL-------------RRKYDQEATNRRIVMQEKMKLLGNIDaLKKELQERKKENQELTSSKCDLSLLLK 1555
Cdd:COG4717   269 LSLILTIAGVLFLvlgllallflllaREKASLGKEAEELQALPALEELEEEE-LEELLAALGLPPDLSPEELLELLDRIE 347

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1556 EAQDAKKNLEKEHTSM--IQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLY 1633
Cdd:COG4717   348 ELQELLREAEELEEELqlEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE 427

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1634 ENnkLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTN--SEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKS 1711
Cdd:COG4717   428 EE--LEEELEELEEELEELEEELEELREELAELEAELEQleEDGELAELLQELEELKAELRELAEEWAALKLALELLEEA 505


                  ....*...
gi 568937376 1712 KLELQELH 1719
Cdd:COG4717   506 REEYREER 513
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1591-2021 4.33e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 4.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1591 MLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEK 1670
Cdd:COG4717    46 MLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1671 TNSE--QKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAL----TERAEVL 1744
Cdd:COG4717   126 QLLPlyQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELqdlaEELEELQ 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1745 QDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQ-----KEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRE 1819
Cdd:COG4717   206 QRLAELEEELEEAQEELEELEEELEQLENELEAAAleerlKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL 285

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1820 LETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEdtkqtnarLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFK 1899
Cdd:COG4717   286 LALLFLLLAREKASLGKEAEELQALPALEELEEEE--------LEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1900 KEIETLKQAAAQKSQQlSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSLpsNTLRESEFRKDADEEK 1979
Cdd:COG4717   358 ELEEELQLEELEQEIA-ALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGEL--EELLEALDEEELEEEL 434

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 568937376 1980 ASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLH 2021
Cdd:COG4717   435 EELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQ 476
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1349-2059 4.52e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.84  E-value: 4.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1349 TLRTQLDCASKALRKAeldmRQLQTSNSSLTKLLEEIKTCRAItdseciqllHEKESLAASE-----RTLLAEKEELlsE 1423
Cdd:COG5022   759 YLRRRYLQALKRIKKI----QVIQHGFRLRRLVDYELKWRLFI---------KLQPLLSLLGsrkeyRSYLACIIKL--Q 823

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1424 NRIITEKLSKQSEEVARLEMGLNEKITYLTSEKevacqkvakLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRR 1503
Cdd:COG5022   824 KTIKREKKLRETEEVEFSLKAEVLIQKFGRSLK---------AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKSI 894

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1504 KY--------DQEAT----NRRIVMQEKMKLLGNIDA-LKKELQERKKENQ---ELTSSKCDLSLL-----LKEAQDAKK 1562
Cdd:COG5022   895 SSlklvnlelESEIIelkkSLSSDLIENLEFKTELIArLKKLLNNIDLEEGpsiEYVKLPELNKLHeveskLKETSEEYE 974

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1563 NLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQtlILEKEARAKESETSLYENNKLHGRV 1642
Cdd:COG5022   975 DLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAE--LQSASKIISSESTELSILKPLQKLK 1052

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1643 VLLEEEIQRLRVCSEQLQTEN--------FTLTQEKTNSEQKVeeiIKEKELLSAETaQLAANIETLKSDFAALSKSKLE 1714
Cdd:COG5022  1053 GLLLLENNQLQARYKALKLRRensllddkQLYQLESTENLLKT---INVKDLEVTNR-NLVKPANVLQFIVAQMIKLNLL 1128

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1715 LQELHSCLTKILDdlrlnhevalteraevLQDNKNLLAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAqtNSHISA 1794
Cdd:COG5022  1129 QEISKFLSQLVNT----------------LEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQ--SALYDE 1190

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1795 NLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEdAMQIMEQMTKEKTETLASLEDTKQTNarlqneldtlkENN 1874
Cdd:COG5022  1191 KSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISE-GWVPTEYSTSLKGFNNLNKKFDTPAS-----------MSN 1258

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1875 LKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENV--KLAEELGRTRDEVtSHQKLEEERSVLNN 1952
Cdd:COG5022  1259 EKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLrwKSATEVNYNSEEL-DDWCREFEISDVDE 1337

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1953 QLLEMKKSLPSNTLRESEfrkdadeekasLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKslhSVVQTLESDKV 2032
Cdd:COG5022  1338 ELEELIQAVKVLQLLKDD-----------LNKLDELLDACYSLNPAEIQNLKSRYDPADKENNLPK---EILKKIEALLI 1403

                         730       740
                  ....*....|....*....|....*..
gi 568937376 2033 KLELKVKNLELQLKENKRQLSSSSGNT 2059
Cdd:COG5022  1404 KQELQLSLEGKDETEVHLSEIFSEEKS 1430
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1119-2073 4.76e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 45.55  E-value: 4.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1119 LIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDS 1198
Cdd:pfam01576   14 LQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1199 LEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLvkdkDDVIQKLQsayeelvKDQKALVQEIE 1278
Cdd:pfam01576   94 LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLL----EDQNSKLS-------KERKLLEERIS 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1279 DLTTEKKSAAEKQMSLDNtcltlkaerenllqtnrdlqfekdtLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCAS 1358
Cdd:pfam01576  163 EFTSNLAEEEEKAKSLSK-------------------------LKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGES 217

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1359 KALRKAELDMR-QLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSEnRIITEKLSKQ--- 1434
Cdd:pfam01576  218 TDLQEQIAELQaQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQrrd 296

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1435 -SEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLladRESSIKTIGDLRRKYDQEATNRR 1513
Cdd:pfam01576  297 lGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEM---RQKHTQALEELTEQLEQAKRNKA 373

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1514 IVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLL 1593
Cdd:pfam01576  374 NLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAE 453

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1594 RDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTenftLTQEKTNS 1673
Cdd:pfam01576  454 GKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLST----LQAQLSDM 529

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1674 EQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDL--RLNHEVALTERAEVLQDN-KNL 1750
Cdd:pfam01576  530 KKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLlvDLDHQRQLVSNLEKKQKKfDQM 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1751 LAEKREMMLRN-------------------------EEALKEKEKLEESYFILQKEISQLAQTNSHISANLLESQSENRT 1805
Cdd:pfam01576  610 LAEEKAISARYaeerdraeaeareketralslaralEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRA 689

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1806 LRKDKSKLTLKIRELETlhSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQ-----NELDTLKENNLKTVEE 1880
Cdd:pfam01576  690 LEQQVEEMKTQLEELED--ELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQlvkqvRELEAELEDERKQRAQ 767

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1881 LNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERS-VLNNQLLEMKK 1959
Cdd:pfam01576  768 AVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLkNLEAELLQLQE 847

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1960 SLPSNTLRESEFRKDADEEKASLQKSISLTSALLTEK-------------------DAELEKLRNEVTVLRGENATAK-- 2018
Cdd:pfam01576  848 DLAASERARRQAQQERDELADEIASGASGKSALQDEKrrleariaqleeeleeeqsNTELLNDRLRKSTLQVEQLTTEla 927

                          970       980       990      1000      1010
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 568937376  2019 SLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQ 2073
Cdd:pfam01576  928 AERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLEEQ 982
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1608-2042 4.79e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 4.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1608 EEIREIQQTLILEKEARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELL 1687
Cdd:PRK02224  289 EELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAEL 368

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1688 SAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEVLQDNKNLLAEKREMMLRNEEA--L 1765
Cdd:PRK02224  369 ESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAeaL 448

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1766 KEKEKLEESYFILqkEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTA--------AQTAEDAMQ 1837
Cdd:PRK02224  449 LEAGKCPECGQPV--EGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDrierleerREDLEELIA 526

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1838 IMEQMTKEKTETLASLEDTKQtnaRLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQ------AAAQ 1911
Cdd:PRK02224  527 ERRETIEEKRERAEELRERAA---ELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERirtllaAIAD 603

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1912 KSQQLSALQEENVKLAEELGRTRDEVTS----HQKLEEERSVLNNQLLEMKKSLPSNTLRESEFRKDA-DEEKASLQKSI 1986
Cdd:PRK02224  604 AEDEIERLREKREALAELNDERRERLAEkrerKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDElREERDDLQAEI 683

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376 1987 sltsALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLES--DKVKLELKVKNLE 2042
Cdd:PRK02224  684 ----GAVENELEELEELRERREALENRVEALEALYDEAEELESmyGDLRAELRQRNVE 737
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
904-1341 5.09e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 5.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  904 EDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGE----VTLKAEQSQQ 979
Cdd:COG4717    48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEElreeLEKLEKLLQL 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  980 QAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQD 1059
Cdd:COG4717   128 LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1060 MEELKTQADKAKSltyLLTSAKKEIEVMSEELRGLKSEKQLYAQEAN--------ALKLEKGSLLSKLIEVETKITLLQE 1131
Cdd:COG4717   208 LAELEEELEEAQE---ELEELEEELEQLENELEAAALEERLKEARLLlliaaallALLGLGGSLLSLILTIAGVLFLVLG 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1132 DQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSM--QVL 1209
Cdd:COG4717   285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELeeELQ 364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1210 IEELRFCKDKLMAMS------------------EKARAEKEHLEGQVKKLTAENLVLVKDKDDviQKLQSAYEELVKDQK 1271
Cdd:COG4717   365 LEELEQEIAALLAEAgvedeeelraaleqaeeyQELKEELEELEEQLEELLGELEELLEALDE--EELEEELEELEEELE 442

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568937376 1272 ALVQEIEDLTTEKKSAAE--KQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQ 1341
Cdd:COG4717   443 ELEEELEELREELAELEAelEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 418-655 5.23e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 5.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  418 AADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEK 497
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  498 SRIMELEKDLA--LRAQEVAELRRRLE---SSKPPGDVDMSLSLLQEIS-ALQEKLEAIHTDHQgemtslkehfgaREEA 571
Cdd:COG4942    97 AELEAQKEELAelLRALYRLGRQPPLAlllSPEDFLDAVRRLQYLKYLApARREQAEELRADLA------------ELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  572 FQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIAlwksKLETAIASHQQAMEELKvsfskgigtdsAEFAELKTQI 651
Cdd:COG4942   165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLA----RLEKELAELAAELAELQ-----------QEAEELEALI 229


                  ....
gi 568937376  652 ERLR 655
Cdd:COG4942   230 ARLE 233
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1026-1558 6.52e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.10  E-value: 6.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1026 TKHEEILQNLQKMLADTEDKLKAAQEANRdlMQDmEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEA 1105
Cdd:pfam05483  250 TEKENKMKDLTFLLEESRDKANQLEEKTK--LQD-ENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTI 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1106 NALKLEKGSLLSKLIEVETKITLL-QEDQQKLWSVNETLHLEKERVsEEKQVAEKRYQQEHRDRESLVAEREKLLKEINA 1184
Cdd:pfam05483  327 CQLTEEKEAQMEELNKAKAAHSFVvTEFEATTCSLEELLRTEQQRL-EKNEDQLKIITMELQKKSSELEEMTKFKNNKEV 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1185 AQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQ---- 1260
Cdd:pfam05483  406 ELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEkekl 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1261 ------SAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLE 1334
Cdd:pfam05483  486 knieltAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVK 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1335 ATLQVKQLLSTEAETLRTQLDCASKALRKAELDMR-QLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTL 1413
Cdd:pfam05483  566 CKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKkQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELEL 645

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1414 LAEKEELLSenriITEKLSKQSEEVARLEMGLNEKItyltSEKEVACQKVAKLKKQQDSLLKEKSALEL--------QNG 1485
Cdd:pfam05483  646 ASAKQKFEE----IIDNYQKEIEDKKISEEKLLEEV----EKAKAIADEAVKLQKEIDKRCQHKIAEMValmekhkhQYD 717

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937376  1486 DLLADRESSIktigDLRRKYDQEATNRRIVMQEKMKLLGN-IDALKKELQERKKENQELTSSKCDLSLLLKEAQ 1558
Cdd:pfam05483  718 KIIEERDSEL----GLYKNKEQEQSSAKAALEIELSNIKAeLLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1855-2131 7.07e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.07  E-value: 7.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1855 DTKQTNARLQNELDTLKENNLKTVEELNKSKELLSvenqkmEEFKKEIETLKQAAAQKSQQLSALQEENVKLAE-ELGRT 1933
Cdd:COG5022   814 SYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLI------QKFGRSLKAKKRFSLLKKETIYLQSAQRVELAErQLQEL 887

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1934 RDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKASLQKSISLTSALLTE--KDAELEKLRNEVTVLR 2011
Cdd:COG5022   888 KIDVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEyvKLPELNKLHEVESKLK 967

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 2012 GENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQQMIDFLNSVIVDLQRKNQ 2091
Cdd:COG5022   968 ETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKP 1047

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 568937376 2092 DLKMKVEMMSEA-ALNGNGEDL-----NSYDSDDQEKQSKKKPRLF 2131
Cdd:COG5022  1048 LQKLKGLLLLENnQLQARYKALklrreNSLLDDKQLYQLESTENLL 1093
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
835-953 7.23e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.85  E-value: 7.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  835 ETLEKELQTLKEKfaSTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDR----EDQLVKA 910
Cdd:COG2433   376 LSIEEALEELIEK--ELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERierlERELSEA 453

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 568937376  911 KEKLENDI---AEIMKMSGDNsSQLTKmndELRLKERSVEELQLKL 953
Cdd:COG2433   454 RSEERREIrkdREISRLDREI-ERLER---ELEEERERIEELKRKL 495
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1738-2098 7.43e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 7.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1738 TERAEVLQDNKNLLAEKREMMLRNEEALKEKEKLEESyfilQKEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKI 1817
Cdd:PRK02224  213 SELAELDEEIERYEEQREQARETRDEADEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1818 RELETLHSFTAAQT------AEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVE------------ 1879
Cdd:PRK02224  289 EELEEERDDLLAEAglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEEraeelreeaael 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1880 --ELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQ-KLEEERSVL--NNQL 1954
Cdd:PRK02224  369 esELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTARERVeeAEAL 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1955 LEMKKSLPSNTLRESEFRKDADEEKaslqksisltSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL 2034
Cdd:PRK02224  449 LEAGKCPECGQPVEGSPHVETIEED----------RERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERR 518

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568937376 2035 ELKVKNLELQ---LKENKRQLSSS---SGNTDAQAEE-DERAQESQQMIDFLNSVIVDLQRKNQDLKMKVE 2098
Cdd:PRK02224  519 EDLEELIAERretIEEKRERAEELrerAAELEAEAEEkREAAAEAEEEAEEAREEVAELNSKLAELKERIE 589
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1599-1798 8.42e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 8.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1599 LQEECQKLNEEIREIQQTLILEKEARAKESETslyennklhgRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVE 1678
Cdd:COG4913   257 IRELAERYAAARERLAELEYLRAALRLWFAQR----------RLELLEAELEELRAELARLEAELERLEARLDALREELD 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1679 EIikEKELLSAETAQlaanIETLKSDFAALSKSKLELQELHSCLTKILDDLRL---NHEVALTERAEVLQDNKNLLAEKR 1755
Cdd:COG4913   327 EL--EAQIRGNGGDR----LEQLEREIERLERELEERERRRARLEALLAALGLplpASAEEFAALRAEAAALLEALEEEL 400

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 568937376 1756 EmMLRNE--EALKEKEKLEESYFILQKEISQLAQTNSHISANLLE 1798
Cdd:COG4913   401 E-ALEEAlaEAEAALRDLRRELRELEAEIASLERRKSNIPARLLA 444
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1145-1355 8.63e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 8.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1145 LEKERVSEEKQVAEKRYQQEHRDRESLVAEREK--LLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFckDKLMA 1222
Cdd:COG4913   218 LEEPDTFEAADALVEHFDDLERAHEALEDAREQieLLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRL--ELLEA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1223 MSEKARAEKEHLEGQVKKLTAEnlvlVKDKDDVIQKLQSAYEELVKDQKA-LVQEIEDLTTEKKSAAEKQMSLDNTC--- 1298
Cdd:COG4913   296 ELEELRAELARLEAELERLEAR----LDALREELDELEAQIRGNGGDRLEqLEREIERLERELEERERRRARLEALLaal 371

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376 1299 -LTLKAERENLLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLD 1355
Cdd:COG4913   372 gLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIA 429
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
805-1164 1.17e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.74  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  805 KANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELE 884
Cdd:COG4372    11 ARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  885 KLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQ 964
Cdd:COG4372    91 AAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALE 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  965 KSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTED 1044
Cdd:COG4372   171 QELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEE 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1045 KLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVET 1124
Cdd:COG4372   251 LLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLEL 330

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 568937376 1125 KITLLQEDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQE 1164
Cdd:COG4372   331 ALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGVADG 370
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1131-1443 1.20e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.12  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1131 EDQQKLWSVNETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEEllkmhmendsleaskvsmqVLI 1210
Cdd:PLN02939  114 EQQTNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGK-------------------INI 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1211 EELRFCK-DKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAE 1289
Cdd:PLN02939  175 LEMRLSEtDARIKLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAE 254

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1290 KqmslDNTCLTLKAERENLLQTNRDLQFekdTLRQGQEKLSASleATLQVKQLLStEAETLRTQLDCASKALRKAELDMR 1369
Cdd:PLN02939  255 T----EERVFKLEKERSLLDASLRELES---KFIVAQEDVSKL--SPLQYDCWWE-KVENLQDLLDRATNQVEKAALVLD 324

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1370 QLQTSNSSLTKL---LEEIKTCRaiTDSECIQLLHEKesLAASERTLLAEKEELLSENRI-------ITEKLSKQSEEVA 1439
Cdd:PLN02939  325 QNQDLRDKVDKLeasLKEANVSK--FSSYKVELLQQK--LKLLEERLQASDHEIHSYIQLyqesikeFQDTLSKLKEESK 400


                  ....
gi 568937376 1440 RLEM 1443
Cdd:PLN02939  401 KRSL 404
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 678-1162 1.21e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   678 KEMETMQAKLMKIIKEKEDSLEAVKARLDSAED---QHLVEMEDTlnklQEAEIKVKELEVLQAKYTEQSEVIGNFTSQ- 753
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFRdlqGQLAHAKKQ----QELQQRYAELCAAAITCTAQCEKLEKIHLQe 463

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   754 ----LSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANsitkELQEKELVLTGLQDSLNQ 829
Cdd:TIGR00618  464 saqsLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDID----NPGPLTRRMQRGEQTYAQ 539

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   830 VNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLREnLTDMEAKFKEKDDREDQLVK 909
Cdd:TIGR00618  540 LETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQD-LTEKLSEAEDMLACEQHALL 618

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   910 AKEKLENDIAEImkmsgdnSSQLTKMNDELRLKERSVEELQLKLTKANENASFL--------QKSIGEVTLKAEQSQQQA 981
Cdd:TIGR00618  619 RKLQPEQDLQDV-------RLHLQQCSQELALKLTALHALQLTLTQERVREHALsirvlpkeLLASRQLALQKMQSEKEQ 691

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   982 ARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDME 1061
Cdd:TIGR00618  692 LTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVT 771

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1062 ELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLEKGSLLSKliEVETKITLLQEDQQKLWSVNE 1141
Cdd:TIGR00618  772 AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQ--EEEQFLSRLEEKSATLGEITH 849

                          490       500
                   ....*....|....*....|.
gi 568937376  1142 TLHLEKERVSEEKQVAEKRYQ 1162
Cdd:TIGR00618  850 QLLKYEECSKQLAQLTQEQAK 870
COG5022 COG5022
Myosin heavy chain [General function prediction only];
783-1148 1.31e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.30  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  783 QQLEGAEKQIKNLETErNAESSKANSITKELQEKELVLT-GLQDSLNQVNQVKETLEKELQTLKEKfaSTSEEAVSAQTR 861
Cdd:COG5022   875 QRVELAERQLQELKID-VKSISSLKLVNLELESEIIELKkSLSSDLIENLEFKTELIARLKKLLNN--IDLEEGPSIEYV 951

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  862 MQDTVNKLHQKEeqfnvlsSELEKLRENLTDMeakFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSqLTKMNDELRL 941
Cdd:COG5022   952 KLPELNKLHEVE-------SKLKETSEEYEDL---LKKSTILVREGNKANSELKNFKKELAELSKQYGA-LQESTKQLKE 1020

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  942 KERSVEELQLKLTKANENASFL------QKSIGEVTLKAEQSQQQAarKHEEEKKELEEKLLELEKKMETSYNQCQDLKA 1015
Cdd:COG5022  1021 LPVEVAELQSASKIISSESTELsilkplQKLKGLLLLENNQLQARY--KALKLRRENSLLDDKQLYQLESTENLLKTINV 1098

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1016 KYEKASSETKTKHEEILQNLQKMLADTeDKLKAAQEANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLK 1095
Cdd:COG5022  1099 KDLEVTNRNLVKPANVLQFIVAQMIKL-NLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAAL 1177

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568937376 1096 SEKQLYaqEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVN-ETLHLEKE 1148
Cdd:COG5022  1178 SEKRLY--QSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGdKLKKLISE 1229
PRK01156 PRK01156
chromosome segregation protein; Provisional
 732-1308 1.44e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 43.74  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  732 ELEVLQAKYTEQSEVIGNFTSQLSavkekllDLDALRKANSEGKLELETLRQQLEGAE-------KQIKNLETERNAESS 804
Cdd:PRK01156  160 EINSLERNYDKLKDVIDMLRAEIS-------NIDYLEEKLKSSNLELENIKKQIADDEkshsitlKEIERLSIEYNNAMD 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  805 KANSITKELQEkelvLTGLQDSLNQVNQVKETLEKELQTLKEKFAS-----------TSEEAVSAQTRMQDTVNKLHQKE 873
Cdd:PRK01156  233 DYNNLKSALNE----LSSLEDMKNRYESEIKTAESDLSMELEKNNYykeleerhmkiINDPVYKNRNYINDYFKYKNDIE 308

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  874 EQFNVLS---SELEKLREN---LTDMEA---KFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKER 944
Cdd:PRK01156  309 NKKQILSnidAEINKYHAIikkLSVLQKdynDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIER 388

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  945 SVEELQLKLTKANENASFLQKSIGEVTLKAEQ-SQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSE 1023
Cdd:PRK01156  389 MSAFISEILKIQEIDPDAIKKELNEINVKLQDiSSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSN 468

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1024 TKTKH-EEILQNLQKMLADTEDKLKAAQEANRDLMQdMEELKTQADKAKSLTY--LLTSAKKEIEVMSEELRGLKSEKQL 1100
Cdd:PRK01156  469 HIINHyNEKKSRLEEKIREIEIEVKDIDEKIVDLKK-RKEYLESEEINKSINEynKIESARADLEDIKIKINELKDKHDK 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1101 YaqeaNALKLEKGSLlsKLIEVETKITLLQEDQQKLWSVN-ETLHLEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLL 1179
Cdd:PRK01156  548 Y----EEIKNRYKSL--KLEDLDSKRTSWLNALAVISLIDiETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSI 621

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1180 KEInaaQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEhLEGQVKKLTaENLVLVKDKDDVIQKL 1259
Cdd:PRK01156  622 REI---ENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKE-ITSRINDIE-DNLKKSRKALDDAKAN 696

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 568937376 1260 QSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENL 1308
Cdd:PRK01156  697 RARLESTIEILRTRINELSDRINDINETLESMKKIKKAIGDLKRLREAF 745
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
355-526 1.49e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 43.69  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  355 ALKEKQQHIEQLLAE---RDLERAEVAKATS-----------HVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAAD 420
Cdd:COG2433   347 AYKNKFERVEKKVPPdvdRDEVKARVIRGLSieealeeliekELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLE 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  421 REKVELLNQLEEEKRKVEDLQFRVEEESItkgdletQTKLEHARTKELEQsllfEKTKADKLQRELEDtrvatvsEKSRI 500
Cdd:COG2433   427 AEVEELEAELEEKDERIERLERELSEARS-------EERREIRKDREISR----LDREIERLERELEE-------ERERI 488

                         170       180
                  ....*....|....*....|....*..
gi 568937376  501 MELEKDLA-LRAQEVAELRRRLESSKP 526
Cdd:COG2433   489 EELKRKLErLKELWKLEHSGELVPVKV 515
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1013-1482 1.51e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1013 LKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKaksltylLTSAKKEIEVMSEELR 1092
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEE-------LEELEAELEELREELE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1093 GLKSEKQLYA--QEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNETLHLEKERVSEEKQ----VAEKRYQQEHR 1166
Cdd:COG4717   120 KLEKLLQLLPlyQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEqlslATEEELQDLAE 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1167 DRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQvLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENL 1246
Cdd:COG4717   200 ELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAA-LEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGV 278

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1247 VLVkdkddVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLRQGQ 1326
Cdd:COG4717   279 LFL-----VLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELL 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1327 EKLsASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMRQLQtsnssltKLLEEIKTCRAITDSECIQLLHEKEsl 1406
Cdd:COG4717   354 REA-EELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQ-------ELKEELEELEEQLEELLGELEELLE-- 423

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376 1407 AASERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYLTSEKEV--ACQKVAKLKKQQDSLLKEKSALEL 1482
Cdd:COG4717   424 ALDEEELEEELEELEEELEELEEELEELREELAELE----AELEQLEEDGELaeLLQELEELKAELRELAEEWAALKL 497
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
755-1085 1.55e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  755 SAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVK 834
Cdd:COG4372    31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEA 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  835 ETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREdqLVKAKEKL 914
Cdd:COG4372   111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAE--AEQALDEL 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  915 ENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEE 994
Cdd:COG4372   189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  995 KLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKSLT 1074
Cdd:COG4372   269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLV 348

                         330
                  ....*....|.
gi 568937376 1075 YLLTSAKKEIE 1085
Cdd:COG4372   349 GLLDNDVLELL 359
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1667-1929 1.61e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1667 TQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHScltkilddlrlnhevALTERAEVLQD 1746
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR---------------ALEQELAALEA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1747 NKNLLAEKREMMLRNEEALKEKekleesyfiLQKEISQLAQTNSHISANLLESQSENRTLrkdkskltlkIRELETLHSF 1826
Cdd:COG4942    84 ELAELEKEIAELRAELEAQKEE---------LAELLRALYRLGRQPPLALLLSPEDFLDA----------VRRLQYLKYL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1827 TAAQtaedaMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLK 1906
Cdd:COG4942   145 APAR-----REQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219

                         250       260
                  ....*....|....*....|...
gi 568937376 1907 QAAAQKSQQLSALQEENVKLAEE 1929
Cdd:COG4942   220 QEAEELEALIARLEAEAAAAAER 242
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1154-1447 1.81e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 43.35  E-value: 1.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1154 KQVAEKRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEH 1233
Cdd:pfam07888   54 NRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRE 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1234 LEGQVKKLTAENLvlvkDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSLdntCLTLKAERENLLQTNR 1313
Cdd:pfam07888  134 LEEDIKTLTQRVL----ERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSL---SKEFQELRNSLAQRDT 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1314 DLQFEKDTLRQGQEKLSASLEATLQVKQLLsteaETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITD 1393
Cdd:pfam07888  207 QVLQLQDTITTLTQKLTTAHRKEAENEALL----EELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAA 282

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568937376  1394 SECIQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNE 1447
Cdd:pfam07888  283 QLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQE 336
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 404-1618 2.14e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 43.50  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   404 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQ----------FRVEEESITKGDLETQTKlehARTKELEQSLL 473
Cdd:TIGR01612  541 EIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEkeikdlfdkyLEIDDEIIYINKLKLELK---EKIKNISDKNE 617

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   474 FEKtKADKLQRELEDTRvATVSEKSRIMELEKDLALRAQEVAELRRRLESSKP-PGDVDmslSLLQEISALQEKLEAIHT 552
Cdd:TIGR01612  618 YIK-KAIDLKKIIENNN-AYIDELAKISPYQVPEHLKNKDKIYSTIKSELSKIyEDDID---ALYNELSSIVKENAIDNT 692

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   553 DHQGEMTSLKehfgAREEAFQKEIKALHTATEKLSKENeslrskLDHANKENSDVIALWKSKLETAIASH-QQAMEELKV 631
Cdd:TIGR01612  693 EDKAKLDDLK----SKIDKEYDKIQNMETATVELHLSN------IENKKNELLDIIVEIKKHIHGEINKDlNKILEDFKN 762

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   632 ---SFSKGIGTDSAEFAEL---KTQIERLRLDYQHE-----IESLQSKQDSERSA-HAKEMETMQAKLMKIIKE----KE 695
Cdd:TIGR01612  763 kekELSNKINDYAKEKDELnkyKSKISEIKNHYNDQinidnIKDEDAKQNYDKSKeYIKTISIKEDEIFKIINEmkfmKD 842

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   696 DSLEAV----------KARLDSAEDQhlveMEDTLNKLQeAEIKVKELEVLQAKYTEQSEVIGNFTsqlSAVKEKLLDLD 765
Cdd:TIGR01612  843 DFLNKVdkfinfenncKEKIDSEHEQ----FAELTNKIK-AEISDDKLNDYEKKFNDSKSLINEIN---KSIEEEYQNIN 914

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   766 ALRKANSEGKL------ELETLR-QQLEGAEKQIKNLETERNAESSKA-------NSITKELQEKELVLTGLqdSLNQVN 831
Cdd:TIGR01612  915 TLKKVDEYIKIcentkeSIEKFHnKQNILKEILNKNIDTIKESNLIEKsykdkfdNTLIDKINELDKAFKDA--SLNDYE 992

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   832 QVKETLEKELQTLKEKFASTSEEAVSAQtrmqdtvnkLHQKEEQFNVLSSELEKLRENLTDME-----AKFKEKDDREDQ 906
Cdd:TIGR01612  993 AKNNELIKYFNDLKANLGKNKENMLYHQ---------FDEKEKATNDIEQKIEDANKNIPNIEiaihtSIYNIIDEIEKE 1063

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   907 LVKAKEKLENdiaEIMKMSGDNSSQLTKMNDELRLKERS--VEELQLKLTkanENASFLQKSIGEVtlkaeqsqQQAARK 984
Cdd:TIGR01612 1064 IGKNIELLNK---EILEEAEINITNFNEIKEKLKHYNFDdfGKEENIKYA---DEINKIKDDIKNL--------DQKIDH 1129

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   985 HEEEKKELEEKLLELEKKMETSYNQCQDL--KAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEanrdlMQDMEE 1062
Cdd:TIGR01612 1130 HIKALEEIKKKSENYIDEIKAQINDLEDVadKAISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNE-----IAEIEK 1204

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1063 LKTQADKAK--SLTYLLTSAKKEIEVMSEELRglKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVN 1140
Cdd:TIGR01612 1205 DKTSLEEVKgiNLSYGKNLGKLFLEKIDEEKK--KSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNIS 1282

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1141 ETLHlekervseekqvaEKRYQQEHRDRESLVAEREKLLK---------EINAAQEELLK------MHMENDSLEASKVS 1205
Cdd:TIGR01612 1283 HDDD-------------KDHHIISKKHDENISDIREKSLKiiedfseesDINDIKKELQKnlldaqKHNSDINLYLNEIA 1349

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1206 MQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKK 1285
Cdd:TIGR01612 1350 NIYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKDIDECIKKIKELKN 1429

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1286 SAAEKQMSLDNTCLTLKAEREN--LLQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLST--EAETLRTQLDCASKAL 1361
Cdd:TIGR01612 1430 HILSEESNIDTYFKNADENNENvlLLFKNIEMADNKSQHILKIKKDNATNDHDFNINELKEHidKSKGCKDEADKNAKAI 1509

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1362 RKAELDMRQLQtsnSSLTKLLE-----EIKTCRAITDSECIQLLHEKESlAASERTLLAEKEElLSENRIITEKLSKQsE 1436
Cdd:TIGR01612 1510 EKNKELFEQYK---KDVTELLNkysalAIKNKFAKTKKDSEIIIKEIKD-AHKKFILEAEKSE-QKIKEIKKEKFRIE-D 1583

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1437 EVARLEMGLNEKITYLTSEK--EVACQKVAKLKKQQDSLLKEKSALELQNGDLLAD-RESSIKTIGDLR---RKYDQEAT 1510
Cdd:TIGR01612 1584 DAAKNDKSNKAAIDIQLSLEnfENKFLKISDIKKKINDCLKETESIEKKISSFSIDsQDTELKENGDNLnslQEFLESLK 1663

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1511 NRRIVMQEKMKLLGNIDALKKELQ---ERKKENQEltsskcdLSLLLKEAQDAKKNLEKEHTSmiqaKDNLNAELKTCCC 1587
Cdd:TIGR01612 1664 DQKKNIEDKKKELDELDSEIEKIEidvDQHKKNYE-------IGIIEKIKEIAIANKEEIESI----KELIEPTIENLIS 1732

                         1290      1300      1310
                   ....*....|....*....|....*....|.
gi 568937376  1588 EKNMLLRDGLNLQEECQKLNEEIREIQQTLI 1618
Cdd:TIGR01612 1733 SFNTNDLEGIDPNEKLEEYNTEIGDIYEEFI 1763
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 679-851 2.20e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  679 EMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHlvemEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNftsqlsaVK 758
Cdd:COG1579    21 RLEHRLKELPAELAELEDELAALEARLEAAKTEL----EDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN-------NK 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  759 EklldLDALRKansegklELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLE 838
Cdd:COG1579    90 E----YEALQK-------EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAEL 158

                         170
                  ....*....|...
gi 568937376  839 KELQTLKEKFAST 851
Cdd:COG1579   159 EELEAEREELAAK 171
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 1839-2021 2.32e-03

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 42.44  E-value: 2.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1839 MEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNkskellsvenQKMEEFKKEIETLKQAAAQKSQQLSA 1918
Cdd:pfam09787   49 LEELRQERDLLREEIQKLRGQIQQLRTELQELEAQQQEEAESSR----------EQLQELEEQLATERSARREAEAELER 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1919 LQEENVKLAEELGRTRDE-VTSHQKLEEERSVLNNQLleMKKSLPSNTLRESEFRKDADEEkaSLQKSISLTSALLTEKD 1997
Cdd:pfam09787  119 LQEELRYLEEELRRSKATlQSRIKDREAEIEKLRNQL--TSKSQSSSSQSELENRLHQLTE--TLIQKQTMLEALSTEKN 194

                          170       180
                   ....*....|....*....|....*..
gi 568937376  1998 A---ELEKLRNEVTVLRGENATAKSLH 2021
Cdd:pfam09787  195 SlvlQLERMEQQIKELQGEGSNGTSIN 221
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1822-2056 2.46e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1822 TLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKEnnlktveELNKSKELLSVENQKMEEFKKE 1901
Cdd:COG4942    12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER-------RIAALARRIRALEQELAALEAE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1902 IETLKQAAAQKSQQLSALQEENVKLAEELGRTRDE------VTSHQKLEEERSV-----LNNQLLEMKKSLPSNTLRESE 1970
Cdd:COG4942    85 LAELEKEIAELRAELEAQKEELAELLRALYRLGRQpplallLSPEDFLDAVRRLqylkyLAPARREQAEELRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1971 FRKDADEEKASLQKSIsltsALLTEKDAELEKLRNEV-TVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENK 2049
Cdd:COG4942   165 LRAELEAERAELEALL----AELEEERAALEALKAERqKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                  ....*..
gi 568937376 2050 RQLSSSS 2056
Cdd:COG4942   241 ERTPAAG 247
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 673-918 2.61e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 42.71  E-value: 2.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   673 RSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTS 752
Cdd:pfam05667  231 LASRLTPEEYRKRKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAELLSSFSGSSTTDTGLTKGSRFTHTEKLQFTN 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   753 QLSAVKEKLL----DLDALRKANSEgklELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLN 828
Cdd:pfam05667  311 EAPAATSSPPtkveTEEELQQQREE---ELEELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQYK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   829 ------------QVNQVKetLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQ----KEEQFNVLSSELEKLRENLTD 892
Cdd:pfam05667  388 vkkktldllpdaEENIAK--LQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEaksnKEDESQRKLEEIKELREKIKE 465

                          250       260
                   ....*....|....*....|....*.
gi 568937376   893 MEAKFKEKDDREDQLVKAKEKLENDI 918
Cdd:pfam05667  466 VAEEAKQKEELYKQLVAEYERLPKDV 491
mukB PRK04863
chromosome partition protein MukB;
852-1243 2.75e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  852 SEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREdQLVKAKEKLENDIAeimKMSGDnssq 931
Cdd:PRK04863  285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKIE---RYQAD---- 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  932 LTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEvtLKAEQSQQQAArkheeekkeleekllelEKKMETSYNQCQ 1011
Cdd:PRK04863  357 LEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDE--LKSQLADYQQA-----------------LDVQQTRAIQYQ 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1012 DLKAKYEKASSETKTKHEEiLQNLQKMLADTEDKLKAAQEANRDLMQDM---EELKTQADKAKSltyLLTSAKKEIE--- 1085
Cdd:PRK04863  418 QAVQALERAKQLCGLPDLT-ADNAEDWLEEFQAKEQEATEELLSLEQKLsvaQAAHSQFEQAYQ---LVRKIAGEVSrse 493

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1086 ---VMSEELRGLKSEKQLyAQEANALKLEKGSLLSKLIEVETKITLLQEDQQK----------LWSVNETLHLEKERVSE 1152
Cdd:PRK04863  494 awdVARELLRRLREQRHL-AEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRlgknlddedeLEQLQEELEARLESLSE 572

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1153 EKQVAEKRYQQEHRDRESLVAEREKLLK---EINAAQEEL--LKMHMENDSLEASKVS--MQVLIEELRfckdKLMAMSE 1225
Cdd:PRK04863  573 SVSEARERRMALRQQLEQLQARIQRLAArapAWLAAQDALarLREQSGEEFEDSQDVTeyMQQLLERER----ELTVERD 648

                         410
                  ....*....|....*...
gi 568937376 1226 KARAEKEHLEGQVKKLTA 1243
Cdd:PRK04863  649 ELAARKQALDEEIERLSQ 666
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
410-588 2.79e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 2.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  410 DQLRTMVEAADREKVELLNQLEEEKRKVEDLQ-----FRVEEESItkgDLETQTKLEHARTKELEQSLL-------FEKT 477
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRKELEEAEaaleeFRQKNGLV---DLSEEAKLLLQQLSELESQLAearaelaEAEA 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  478 KADKLQRELEDTR--VATVSEKSRIMELEKDLALRAQEVAELRRRLESSKPpgDVdmsLSLLQEISALQEKLEAIHTDHQ 555
Cdd:COG3206   241 RLAALRAQLGSGPdaLPELLQSPVIQQLRAQLAELEAELAELSARYTPNHP--DV---IALRAQIAALRAQLQQEAQRIL 315

                         170       180       190
                  ....*....|....*....|....*....|...
gi 568937376  556 GEMTSLKEHFGAREEAFQKEIKALHTATEKLSK 588
Cdd:COG3206   316 ASLEAELEALQAREASLQAQLAQLEARLAELPE 348
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 775-944 3.20e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.76  E-value: 3.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  775 KLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKelvltgLQDSLNQvnqvketLEKELQTLKEKFastsEE 854
Cdd:COG0542   403 RMEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFERLAE------LRDELAE-------LEEELEALKARW----EA 465

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  855 AVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDredqlvkakeklENDIAEIM---------KMS 925
Cdd:COG0542   466 EKELIEEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLREEVT------------EEDIAEVVsrwtgipvgKLL 533

                         170
                  ....*....|....*....
gi 568937376  926 GDNSSQLTKMNDElrLKER 944
Cdd:COG0542   534 EGEREKLLNLEEE--LHER 550
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1461-1710 3.42e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1461 QKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKEn 1540
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE- 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1541 qeltsskcdLSLLLKEAQdakKNLEKEHTSMIQAKDNLNAelktccceknmLLRDGLNLQEECQKLNEEIREIQQTLile 1620
Cdd:COG4942   106 ---------LAELLRALY---RLGRQPPLALLLSPEDFLD-----------AVRRLQYLKYLAPARREQAEELRADL--- 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1621 kearakesetslyenNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIET 1700
Cdd:COG4942   160 ---------------AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224

                         250
                  ....*....|
gi 568937376 1701 LKSDFAALSK 1710
Cdd:COG4942   225 LEALIARLEA 234
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1159-1615 3.48e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1159 KRYQQEHRDRESLVAEREKLLKEINAAQEELLKMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSE--KARAEKEHLEG 1236
Cdd:COG4717    67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQEleALEAELAELPE 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1237 QVKKLtaenlvlvKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMSldntclTLKAERENLLQTNRDLQ 1316
Cdd:COG4717   147 RLEEL--------EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ------DLAEELEELQQRLAELE 212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1317 FEKDTLRQGQEKLSASLEAtLQVKQLLSTEAETLRTQldcasKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSEC 1396
Cdd:COG4717   213 EELEEAQEELEELEEELEQ-LENELEAAALEERLKEA-----RLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLL 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1397 IQLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEVACQKVAKLKKQQDSLLKE 1476
Cdd:COG4717   287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1477 KSALELQNgdLLAdrESSIKTIGDLRRKYDQEatnrrivmQEKMKLLGNIDALKKELQERKKENQEL--TSSKCDLSLLL 1554
Cdd:COG4717   367 ELEQEIAA--LLA--EAGVEDEEELRAALEQA--------EEYQELKEELEELEEQLEELLGELEELleALDEEELEEEL 434

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568937376 1555 KEAQDAKKNLEKEHTSMIQAKDNLNAELKTccceknmLLRDGL--NLQEECQKLNEEIREIQQ 1615
Cdd:COG4717   435 EELEEELEELEEELEELREELAELEAELEQ-------LEEDGElaELLQELEELKAELRELAE 490
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 425-1571 3.64e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 3.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   425 ELLNQLEEEKRKVEDLQFRVEEESitkgdleTQTKLEHARTKElEQSLLFEKTKAD-KLQRELEDTRVATVSEKSRIMEL 503
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESEL-------KELEKKHQQLCE-EKNALQEQLQAEtELCAEAEEMRARLAARKQELEEI 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   504 EKDLALRAQEVAELRRRLESSKPpgdvdmslSLLQEISALQEKLEAIHTDHQgEMTSLKEHFGAREEAFQKEIKALHTAT 583
Cdd:pfam01576   77 LHELESRLEEEEERSQQLQNEKK--------KMQQHIQDLEEQLDEEEAARQ-KLQLEKVTTEAKIKKLEEDILLLEDQN 147

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   584 EKLSKENESLRSKL----DHANKENSDVIALWKSKLEtaiasHQQAMEELKVSFSKGIGTdSAEFAELKTQIERLRLDYQ 659
Cdd:pfam01576  148 SKLSKERKLLEERIseftSNLAEEEEKAKSLSKLKNK-----HEAMISDLEERLKKEEKG-RQELEKAKRKLEGESTDLQ 221

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   660 HEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKArldsaedqhLVEMEDTLNKLQEaeikvkELEVLQAK 739
Cdd:pfam01576  222 EQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKK---------IRELEAQISELQE------DLESERAA 286

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   740 YTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGA-EKQIKNLETERNAESSKANSITKELQEKel 818
Cdd:pfam01576  287 RNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKAlEEETRSHEAQLQEMRQKHTQALEELTEQ-- 364

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   819 vltglqdsLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQfnvlsseLEKLRENLTDMEakfK 898
Cdd:pfam01576  365 --------LEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQ-------LQELQARLSESE---R 426

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   899 EKDDREDQLVKAKEKLENdIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGE--VTLKAEQ 976
Cdd:pfam01576  427 QRAELAEKLSKLQSELES-VSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDerNSLQEQL 505

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   977 SQQQAARKheeekkeleekllELEKKMETSYNQCQDLKAKYEKASS------ETKTKHEEILQNLQKMLADTEDKLKAAQ 1050
Cdd:pfam01576  506 EEEEEAKR-------------NVERQLSTLQAQLSDMKKKLEEDAGtlealeEGKKRLQRELEALTQQLEEKAAAYDKLE 572

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1051 EANRDLMQDMEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGL---------KSEKQLYAQEANALKLEKG--SLLSKL 1119
Cdd:pfam01576  573 KTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAIsaryaeerdRAEAEAREKETRALSLARAleEALEAK 652

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1120 IEVETKITLLQEDQQKLWS----VNETLH-LEKERVSEEKQVAEKRYQQEHRDRESLVAEREKLLKEIN----AAQEElL 1190
Cdd:pfam01576  653 EELERTNKQLRAEMEDLVSskddVGKNVHeLERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNmqalKAQFE-R 731

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1191 KMHMENDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQ---KLQSAYEELV 1267
Cdd:pfam01576  732 DLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKqlkKLQAQMKDLQ 811

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1268 KDQKALVQEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLQFEKDTLrqgQEKLSASLEAtlqvKQLLSTEA 1347
Cdd:pfam01576  812 RELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDEL---ADEIASGASG----KSALQDEK 884

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1348 ETLRTQLDCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERTLLAEKEELLSENRii 1427
Cdd:pfam01576  885 RRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVK-- 962

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1428 teklSKQSEEVARLEmglnekityltsekevacQKVAKLKKQQDSLLKEKSAlelqNGDLLADRESSIKtigDLRRKYDQ 1507
Cdd:pfam01576  963 ----SKFKSSIAALE------------------AKIAQLEEQLEQESRERQA----ANKLVRRTEKKLK---EVLLQVED 1013

                         1130      1140      1150      1160      1170      1180
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568937376  1508 EATNRRIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSM 1571
Cdd:pfam01576 1014 ERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTL 1077
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1645-1832 3.92e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1645 LEEEIQRLRVCSEQLQTENFTLTQEKTNSEQKVEEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTK 1724
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1725 ILDDLRLNHEVAL------------------------TERAEVLQDNKNLLAEKREMMLRNEEALKE-KEKLEESYFILQ 1779
Cdd:COG4942   112 ALYRLGRQPPLALllspedfldavrrlqylkylaparREQAEELRADLAELAALRAELEAERAELEAlLAELEEERAALE 191

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568937376 1780 KEISQLAQTNSHISANLLESQSENRTLRKDKSKLTLKIRELETLHSFTAAQTA 1832
Cdd:COG4942   192 ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 658-2041 4.08e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 42.73  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   658 YQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKvkelevlq 737
Cdd:TIGR01612  472 FEEEWGSYDIKKDIDENSKQDNTVKLILMRMKDFKDIIDFMELYKPDEVPSKNIIGFDIDQNIKAKLYKEIE-------- 543

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   738 akyteqsevignftsqlSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNL---ETERNAESSKANSITKELQ 814
Cdd:TIGR01612  544 -----------------AGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIKDLfdkYLEIDDEIIYINKLKLELK 606

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   815 EKELVLTGLQDSLNQVNQVKETLEKELQTLKEkFASTSEEAVSAQTRMQDTVnklhqkeeqFNVLSSELEKLRENltDME 894
Cdd:TIGR01612  607 EKIKNISDKNEYIKKAIDLKKIIENNNAYIDE-LAKISPYQVPEHLKNKDKI---------YSTIKSELSKIYED--DID 674

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   895 AKFKE-----KDDREDQlVKAKEKLEndiaeimkmsgDNSSQLTKMNDELRLKERSVEELQLKLTKANENasflqkSIGE 969
Cdd:TIGR01612  675 ALYNElssivKENAIDN-TEDKAKLD-----------DLKSKIDKEYDKIQNMETATVELHLSNIENKKN------ELLD 736

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   970 VTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHeeilqNLQKMLADTEDklkaa 1049
Cdd:TIGR01612  737 IIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKNHY-----NDQINIDNIKD----- 806

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1050 qeanrdlmqdmEELKTQADKAKSLTYLLTSAKKEIEVMSEELRGLK----SEKQLYAQEANALKLEKGSLLSKLIEVETK 1125
Cdd:TIGR01612  807 -----------EDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKddflNKVDKFINFENNCKEKIDSEHEQFAELTNK 875

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1126 ITLLQEDQQkLWSVNETLHLEKERVSEEKQVAEKRYQQEHRdreslVAEREKLLKEINAAQEELLKMHMENDSLEA---- 1201
Cdd:TIGR01612  876 IKAEISDDK-LNDYEKKFNDSKSLINEINKSIEEEYQNINT-----LKKVDEYIKICENTKESIEKFHNKQNILKEilnk 949

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1202 --SKVSMQVLIEELRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKL-----QSAYEELVKDQKALV 1274
Cdd:TIGR01612  950 niDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKDASLNDYEAKNNELIKYFNDLKANLgknkeNMLYHQFDEKEKATN 1029

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1275 QEIEDLTTEKKSAAEKQMSLDNTCLTLKAERENLLQTNRDLqFEKDTLRQGQEKLSASLEATLQVKqlLSTEAETLRTQL 1354
Cdd:TIGR01612 1030 DIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIEL-LNKEILEEAEINITNFNEIKEKLK--HYNFDDFGKEEN 1106

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1355 DCASKALRKAELDMRQLQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAasERTLLAEK-EELLSENRIITEKLSK 1433
Cdd:TIGR01612 1107 IKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVA--DKAISNDDpEEIEKKIENIVTKIDK 1184

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1434 QSEevarlemgLNEKITYLTSEkevacqkVAKLKKQQDSLLKEKSaLELQNGdlladressiKTIGDL-RRKYDQEATNR 1512
Cdd:TIGR01612 1185 KKN--------IYDEIKKLLNE-------IAEIEKDKTSLEEVKG-INLSYG----------KNLGKLfLEKIDEEKKKS 1238

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1513 RIVMQEKMKLLGNIDALKKELQERKKENQELTSSKCDLSLLlkeaqDAKKNLEKEHTSMIQAKDNLNAELKtcccEKNML 1592
Cdd:TIGR01612 1239 EHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETF-----NISHDDDKDHHIISKKHDENISDIR----EKSLK 1309

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1593 LRDGLNlqeECQKLNEEIREIQQTLIlekEARAKESETSLYENNKLHGRVVL----LEEEIQRLRVCSEQLQTENFTLTQ 1668
Cdd:TIGR01612 1310 IIEDFS---EESDINDIKKELQKNLL---DAQKHNSDINLYLNEIANIYNILklnkIKKIIDEVKEYTKEIEENNKNIKD 1383

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1669 EKTNSEQKVEEIIKEkellsaetaqlaANIETLKSDFaalsKSKLELQELHSCLTKILDdlrlnhevaltERAEVLQDNK 1748
Cdd:TIGR01612 1384 ELDKSEKLIKKIKDD------------INLEECKSKI----ESTLDDKDIDECIKKIKE-----------LKNHILSEES 1436

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1749 NllaekremmlrNEEALKEKEKLEESYFILQKEISQLAQTNSHIsanlLESQSENRTLRKDKSKLTLKIRELETLHSFTA 1828
Cdd:TIGR01612 1437 N-----------IDTYFKNADENNENVLLLFKNIEMADNKSQHI----LKIKKDNATNDHDFNINELKEHIDKSKGCKDE 1501

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1829 A----QTAEDAMQIMEQMTKEKTETLasledTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVE----NQKMEEFKK 1900
Cdd:TIGR01612 1502 AdknaKAIEKNKELFEQYKKDVTELL-----NKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEaeksEQKIKEIKK 1576

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1901 EIETLKQAAAQKSQ--------QLSALQEEN--VKLAEELGRTRDEVTSHQKLEEERSVL--NNQLLEMKKSLPS-NTLR 1967
Cdd:TIGR01612 1577 EKFRIEDDAAKNDKsnkaaidiQLSLENFENkfLKISDIKKKINDCLKETESIEKKISSFsiDSQDTELKENGDNlNSLQ 1656

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1968 esEFRKDADEEKaslqKSISLTSALLTEKDAELEKLRN---------EVTVLRGENATAKSLHsvvQTLESDKVKLELKV 2038
Cdd:TIGR01612 1657 --EFLESLKDQK----KNIEDKKKELDELDSEIEKIEIdvdqhkknyEIGIIEKIKEIAIANK---EEIESIKELIEPTI 1727


                   ...
gi 568937376  2039 KNL 2041
Cdd:TIGR01612 1728 ENL 1730
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 381-798 4.08e-03

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 42.15  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   381 TSHVGEIEQELALARDGHDQ-HVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEeesitkgdlETQTK 459
Cdd:pfam06160   59 TKSLPDIEELLFEAEELNDKyRFKKAKKALDEIEELLDDIEEDIKQILEELDELLESEEKNREEVE---------ELKDK 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   460 LEHARTKELEQSLLFEKTkADKLQRELED-----TRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSkPPGDVDMSL 534
Cdd:pfam06160  130 YRELRKTLLANRFSYGPA-IDELEKQLAEieeefSQFEELTESGDYLEAREVLEKLEEETDALEELMEDI-PPLYEELKT 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   535 SL---LQEISALQEKLEaihtdhqgemtslKEHFGAREEAFQKEIKALHTATEKLSKENESLRskLDHANKENSDV---I 608
Cdd:pfam06160  208 ELpdqLEELKEGYREME-------------EEGYALEHLNVDKEIQQLEEQLEENLALLENLE--LDEAEEALEEIeerI 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   609 ALWKSKLETAIASHQQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERsaHAKEMETMQAKLM 688
Cdd:pfam06160  273 DQLYDLLEKEVDAKKYVEKNLPE-IEDYLEHAEEQNKELKEELERVQQSYTLNENELERVRGLEK--QLEELEKRYDEIV 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376   689 KIIKEKE-------DSLEAVKARLDSAEDQHlVEMEDTLNKLQEAEIKVKE-LEVLQAK------YTEQSEVIG---NFT 751
Cdd:pfam06160  350 ERLEEKEvayselqEELEEILEQLEEIEEEQ-EEFKESLQSLRKDELEAREkLDEFKLElreikrLVEKSNLPGlpeSYL 428

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 568937376   752 SQLSAVKEKlldLDALRKANSEGKLELETLRQQLEGAEKQIKNLETE 798
Cdd:pfam06160  429 DYFFDVSDE---IEDLADELNEVPLNMDEVNRLLDEAQDDVDTLYEK 472
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 381-798 4.25e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 42.13  E-value: 4.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  381 TSHVGEIEQELALARDGHDQ-HVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEeesitkgdlETQTK 459
Cdd:PRK04778   78 TNSLPDIEEQLFEAEELNDKfRFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVE---------QLKDL 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  460 LEHARTKELEQSLLFEKTkADKLQRELED-----TRVATVSEKSRIMELEKDLALRAQEVAELRRRLEsskppgdvdmsl 534
Cdd:PRK04778  149 YRELRKSLLANRFSFGPA-LDELEKQLENleeefSQFVELTESGDYVEAREILDQLEEELAALEQIME------------ 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  535 sllqEISALQEKLEaihTDHQGEMTSLK--------EHFGAREEAFQKEIKALHTATEKLSKENESLrsKLDHANKENSD 606
Cdd:PRK04778  216 ----EIPELLKELQ---TELPDQLQELKagyrelveEGYHLDHLDIEKEIQDLKEQIDENLALLEEL--DLDEAEEKNEE 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  607 V---IALWKSKLETAIASHQQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQheiesLQSKQDSERSAHAKEMETM 683
Cdd:PRK04778  287 IqerIDQLYDILEREVKARKYVEKNSDT-LPDFLEHAKEQNKELKEEIDRVKQSYT-----LNESELESVRQLEKQLESL 360

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  684 QAKLMKIIK----------EKEDSLEAVKARLDSAEDQHlVEMEDTLNKLQEAEIKVKE-LEVLQAK------YTEQSEV 746
Cdd:PRK04778  361 EKQYDEITEriaeqeiaysELQEELEEILKQLEEIEKEQ-EKLSEMLQGLRKDELEAREkLERYRNKlheikrYLEKSNL 439

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 568937376  747 IGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETE 798
Cdd:PRK04778  440 PGLPEDYLEMFFEVSDEIEALAEELEEKPINMEAVNRLLEEATEDVETLEEE 491
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1398-2127 4.36e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.34  E-value: 4.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1398 QLLHEKESLAASERTLLAEKEELLSENRIITEKLSKQSEEVARLEMGLNEKITYLTSEKEvacqKVAKLKKQQDSLLKEK 1477
Cdd:TIGR00606  210 KYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDN----EIKALKSRKKQMEKDN 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1478 SALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKmkllgnIDALKKELQERKKENQELTSSKCDLSLLLK-- 1555
Cdd:TIGR00606  286 SELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRE------LEKLNKERRLLNQEKTELLVEQGRLQLQADrh 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1556 EAQDAKKNLEKEHTSMIQAKDNLNAELKTCCCEKNMLLRDGLNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYEN 1635
Cdd:TIGR00606  360 QEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLG 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1636 NKLHGRVVLLEEEIQRLRVCSEQLQTenftLTQEKTNSEQKVEEIIKEKELLSaeTAQLAANIETLKSDFAALSKSKLEL 1715
Cdd:TIGR00606  440 RTIELKKEILEKKQEELKFVIKELQQ----LEGSSDRILELDQELRKAERELS--KAEKNSLTETLKKEVKSLQNEKADL 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1716 QELHSCLTKILDDLRlNHEVALTERAEVLQDNKNLLAEKREMMLRNEEAL---------------------KEKEKLEES 1774
Cdd:TIGR00606  514 DRKLRKLDQEMEQLN-HHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELtsllgyfpnkkqledwlhsksKEINQTRDR 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1775 YFILQKEISQLAQTNSHISaNLLESQSENRTLRKDK-----------SKLTLKIRELETLHSFTAAQTAEDAM--QIMEQ 1841
Cdd:TIGR00606  593 LAKLNKELASLEQNKNHIN-NELESKEEQLSSYEDKlfdvcgsqdeeSDLERLKEEIEKSSKQRAMLAGATAVysQFITQ 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1842 MTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQE 1921
Cdd:TIGR00606  672 LTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRN 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1922 ENVKLAEELGRTRDEVTSHQKL-------EEERSVLNNQLLEMKKSLPSNTLRESEFRKDADEEKAS-LQKSISLTSALL 1993
Cdd:TIGR00606  752 KLQKVNRDIQRLKNDIEEQETLlgtimpeEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSdLDRTVQQVNQEK 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1994 TEKDAELEKLRNEVTVLRG----ENATAKSLHSVVQTLESDKVKLELKVKNLElQLKENKRQLSS--SSGNTDAQAEEDE 2067
Cdd:TIGR00606  832 QEKQHELDTVVSKIELNRKliqdQQEQIQHLKSKTNELKSEKLQIGTNLQRRQ-QFEEQLVELSTevQSLIREIKDAKEQ 910

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568937376  2068 RAQESQQMIDFLNSVIVDLQRKNQDLK---MKVEMMSEAALN--GNGEDLNSYDSDDQEKQSKKK 2127
Cdd:TIGR00606  911 DSPLETFLEKDQQEKEELISSKETSNKkaqDKVNDIKEKVKNihGYMKDIENKIQDGKDDYLKQK 975
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 902-1111 4.43e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  902 DREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLK-AEQSQQQ 980
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEiAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  981 AARKHEEEKKELEEKLLELEKKMETSYNQCQDLKA----KYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDL 1056
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAvrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568937376 1057 MQDMEELKTQADKAKS-LTYLLTSAKKEIEVMSEELRGLKSEKQLYAQEANALKLE 1111
Cdd:COG4942   180 LAELEEERAALEALKAeRQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
46 PHA02562
endonuclease subunit; Provisional
 661-926 4.47e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 4.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  661 EIESLQSKQDsersaHAKEMETMQAKLMKIIKEKEDsleAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKY 740
Cdd:PHA02562  182 QIQTLDMKID-----HIQQQIKTYNKNIEEQRKKNG---ENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDP 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  741 TEQSEVIGNFTSQLSAvkeKLLDLDALRKANSEGKlELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEkelvL 820
Cdd:PHA02562  254 SAALNKLNTAAAKIKS---KIEQFQKVIKMYEKGG-VCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDE----L 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  821 TGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQdtvnklhQKEEQFNVLSSELEKLRENLTDmeaKFKEK 900
Cdd:PHA02562  326 EEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEELAKLQDELDK---IVKTK 395

                         250       260
                  ....*....|....*....|....*..
gi 568937376  901 DDredqlvKAKEKLENDIA-EIMKMSG 926
Cdd:PHA02562  396 SE------LVKEKYHRGIVtDLLKDSG 416
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 777-984 4.63e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 4.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  777 ELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLN----QVNQVKETLEKELQTLKEKFASTS 852
Cdd:COG3883    24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAeaeaEIEERREELGERARALYRSGGSVS 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  853 E-EAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQ 931
Cdd:COG3883   104 YlDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEAL 183

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568937376  932 LTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARK 984
Cdd:COG3883   184 LAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1523-1951 4.84e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.06  E-value: 4.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1523 LGNIDALKKELQERKKENQELTSSKCDLSLL---LKEAQDAKKNLEKEHTSMIQAKDN---------LNAELKTCCCEKN 1590
Cdd:COG4717    70 LKELKELEEELKEAEEKEEEYAELQEELEELeeeLEELEAELEELREELEKLEKLLQLlplyqeleaLEAELAELPERLE 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1591 ML---LRDGLNLQEECQKLNEEIREIQQTLILEKE----ARAKESETSLYENNKLHGRVVLLEEEIQRLRVCSEQLQTEn 1663
Cdd:COG4717   150 ELeerLEELRELEEELEELEAELAELQEELEELLEqlslATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE- 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1664 FTLTQEKTNSEQKVEEIIKEKELLSAETAQLAanIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAEV 1743
Cdd:COG4717   229 LEQLENELEAAALEERLKEARLLLLIAAALLA--LLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1744 LQdnknllAEKREMMLRNEEALKEKEKLEESYFILQKEISQLAQTNSHIsanllesQSENRTLRKDKSKLTLKIRELETL 1823
Cdd:COG4717   307 LQ------ALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEEL-------QELLREAEELEEELQLEELEQEIA 373

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1824 HSFTAAQTAEDamqimeqmtkektETLASLEDTKQTNARLQNELDTLKENnlktVEELNKSKELLSVENQKmEEFKKEIE 1903
Cdd:COG4717   374 ALLAEAGVEDE-------------EELRAALEQAEEYQELKEELEELEEQ----LEELLGELEELLEALDE-EELEEELE 435

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 568937376 1904 TLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLN 1951
Cdd:COG4717   436 ELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKA 483
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 659-900 4.91e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  659 QHEIESLQSKQDSERSAhAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhLVEMEDTLNKLQeaeikvKELEVLQA 738
Cdd:COG4942    26 EAELEQLQQEIAELEKE-LAALKKEEKALLKQLAALERRIAALARRIRALEQE-LAALEAELAELE------KEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  739 KYTEQSEVIGNFtsqlsavkeklldLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEkel 818
Cdd:COG4942    98 ELEAQKEELAEL-------------LRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE--- 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  819 vLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFK 898
Cdd:COG4942   162 -LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                  ..
gi 568937376  899 EK 900
Cdd:COG4942   241 ER 242
mukB PRK04863
chromosome partition protein MukB;
567-968 5.16e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 5.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  567 ARE---EAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALW-KSKLETAIASHQQAMEELkvsfskgigtdSA 642
Cdd:PRK04863  783 AREkriEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAfEADPEAELRQLNRRRVEL-----------ER 851

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  643 EFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAvkARLDSAEDQHLVEMEDTLNK 722
Cdd:PRK04863  852 ALADHESQEQQQRSQLEQAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEAEEA--KRFVQQHGNALAQLEPIVSV 929

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  723 LQEAEikvKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLE-----LETLRQQLEGAEKQIKNLET 797
Cdd:PRK04863  930 LQSDP---EQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFSYEDAAEMLAknsdlNEKLRQRLEQAEQERTRARE 1006

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  798 E-RNAESskansitkELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQtrmQDTVNK-LHQKEEQ 875
Cdd:PRK04863 1007 QlRQAQA--------QLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARAR---RDELHArLSANRSR 1075

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  876 FNVLSSELEKLRENLTDMEAKFK--EKD--DREDQLVKAKekleNDIAEIMKMSGDNSsqltkmnDELRLKERSVEELql 951
Cdd:PRK04863 1076 RNQLEKQLTFCEAEMDNLTKKLRklERDyhEMREQVVNAK----AGWCAVLRLVKDNG-------VERRLHRRELAYL-- 1142

                         410
                  ....*....|....*..
gi 568937376  952 kltKANENASFLQKSIG 968
Cdd:PRK04863 1143 ---SADELRSMSDKALG 1156
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
647-832 5.37e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 5.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  647 LKTQIERLR---LDYQHEIESLQSKQ-----DSERSAHAKEMETMQAKLMKI---IKEKEDSLEAVKARLDSAEDQHLVE 715
Cdd:COG3206   180 LEEQLPELRkelEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEAraeLAEAEARLAALRAQLGSGPDALPEL 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  716 MEDT-----LNKLQEAEIkvkELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLD-----LDALRKANSEGKLELETLRQQL 785
Cdd:COG3206   260 LQSPviqqlRAQLAELEA---ELAELSARYTPNHPDVIALRAQIAALRAQLQQeaqriLASLEAELEALQAREASLQAQL 336

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 568937376  786 EGAEKQIKNLeterNAESSKANSITKELQEKELVLTGLQDSLNQVNQ 832
Cdd:COG3206   337 AQLEARLAEL----PELEAELRRLEREVEVARELYESLLQRLEEARL 379
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1213-1742 5.45e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 5.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1213 LRFCKDKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQM 1292
Cdd:COG4717    40 LAFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1293 SLdntcltlkaerENLLQTNRDLQfekdtlrqgqeklsasleatlqvkqllstEAETLRTQLDCASKALRKAELDMRQLQ 1372
Cdd:COG4717   120 KL-----------EKLLQLLPLYQ-----------------------------ELEALEAELAELPERLEELEERLEELR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1373 TSNSSLTKLLEEIKTCRAITDSECIQLLHEKEslaASERTLLAEKEELLSENRIITEKLSKQSEEVARLEmglnEKITYL 1452
Cdd:COG4717   160 ELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEELQQRLAELEEELEEAQEELEELE----EELEQL 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1453 TSEKEVAcQKVAKLKKQQDSLLKEKSALELQ-NGDLLADRESSIKTIGDL-------------RRKYDQEATNRRIVMQE 1518
Cdd:COG4717   233 ENELEAA-ALEERLKEARLLLLIAAALLALLgLGGSLLSLILTIAGVLFLvlgllallflllaREKASLGKEAEELQALP 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1519 KMKLLGNIDaLKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEHTSM--IQAKDNLNAELKTCCCEKNMLLRDG 1596
Cdd:COG4717   312 ALEELEEEE-LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqlEELEQEIAALLAEAGVEDEEELRAA 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1597 LNLQEECQKLNEEIREIQQTLILEKEARAKESETSLYENnklhgrvvlLEEEIQRLRVCSEQLQTENFTLTQEKTNSEQK 1676
Cdd:COG4717   391 LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE---------LEEELEELEEELEELEEELEELREELAELEAE 461

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568937376 1677 VEEIIKEKELlsaetAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVALTERAE 1742
Cdd:COG4717   462 LEQLEEDGEL-----AELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 570-860 5.52e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 41.87  E-value: 5.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  570 EAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAE----FA 645
Cdd:COG5185   242 ESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEeqlaAA 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  646 ELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEdsLEAVKARLDSAEDQHLVEMEDTLNKLQE 725
Cdd:COG5185   322 EAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVE--LSKSSEELDSFKDTIESTKESLDEIPQN 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  726 AEIKVKE-LEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESS 804
Cdd:COG5185   400 QRGYAQEiLATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYDEINRSVRSK 479

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568937376  805 KANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQT 860
Cdd:COG5185   480 KEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGY 535
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1218-1961 6.06e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.88  E-value: 6.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1218 DKLMAMSEKARAEKEHLEGQVKKLTAENLVLVKDKDDVIQKLQSAYEELVKDQKALV------QEIEDLTTEKKSAAEKQ 1291
Cdd:TIGR00618  176 DQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLRealqqtQQSHAYLTQKREAQEEQ 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1292 MSLDNTCLTLKAERENL--LQTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRKAELDMR 1369
Cdd:TIGR00618  256 LKKQQLLKQLRARIEELraQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVK 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1370 Q---LQTSNSSLTKLLEEIKTCRAITDSECIQLLHEKESLAASE--RTLLAEKEELLSENRIITEKLSKQSEEVArlemg 1444
Cdd:TIGR00618  336 QqssIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQhiHTLQQQKTTLTQKLQSLCKELDILQREQA----- 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1445 lneKITYLTSEKEVACQKVAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYD----QEATNRRIVMQEKM 1520
Cdd:TIGR00618  411 ---TIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKereqQLQTKEQIHLQETR 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1521 KllgnidalKKELQERKKENQELTSSKCDLSLLLKEAQDAKKNLEKEhTSMIQAKDNLNAELKTcccEKNMLLRDGLNLQ 1600
Cdd:TIGR00618  488 K--------KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPL-TRRMQRGEQTYAQLET---SEEDVYHQLTSER 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1601 EECQKLNEEIREIQQTLILEKEARAKESEtslyENNKLHGRVVLLEEEIQRLRVCSEQLQTENFTLtQEKTNSEQKVEEI 1680
Cdd:TIGR00618  556 KQRASLKEQMQEIQQSFSILTQCDNRSKE----DIPNLQNITVRLQDLTEKLSEAEDMLACEQHAL-LRKLQPEQDLQDV 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1681 IKEKELLSAETAQLAANIETLKSDFAAlsksklELQELHSCLTKILDDLRLNHEVALTERaevLQDNKNLLAEKREMMLR 1760
Cdd:TIGR00618  631 RLHLQQCSQELALKLTALHALQLTLTQ------ERVREHALSIRVLPKELLASRQLALQK---MQSEKEQLTYWKEMLAQ 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1761 NEEALKEKEKLEESYFILQKEISQLaqtnshisanlleSQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIME 1840
Cdd:TIGR00618  702 CQTLLRELETHIEEYDREFNEIENA-------------SSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  1841 QMTKEkTETLASLEDTKQTNARLQNELDTLkennlktveeLNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQ 1920
Cdd:TIGR00618  769 EVTAA-LQTGAELSHLAAEIQFFNRLREED----------THLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRL 837

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 568937376  1921 EENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKSL 1961
Cdd:TIGR00618  838 EEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1872-2127 6.94e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 41.48  E-value: 6.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1872 ENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSA-LQEENVKLAEELGRTRDEVTSHQKLEEERSVL 1950
Cdd:COG5185   232 EEALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKrLNENANNLIKQFENTKEKIAEYTKSIDIKKAT 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1951 NNQLLEMKKSLPSNTL--RESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGEnataKSLHSVVQTLE 2028
Cdd:COG5185   312 ESLEEQLAAAEAEQELeeSKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKSS----EELDSFKDTIE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 2029 SDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQqmidfLNSVIVDLQRKNQDLKMKVEMMSEAALNGN 2108
Cdd:COG5185   388 STKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQA-----TSSNEEVSKLLNELISELNKVMREADEESQ 462

                         250
                  ....*....|....*....
gi 568937376 2109 GEDLNSYDSDDQEKQSKKK 2127
Cdd:COG5185   463 SRLEEAYDEINRSVRSKKE 481
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1009-1195 7.24e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 7.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1009 QCQDLKAKYEKASSETKT--KHEEILQNLQKmLADTEDKLKAAQEANRDLMQDMEElktqadkaksltylLTSAKKEIEV 1086
Cdd:COG4913   625 ELAEAEERLEALEAELDAlqERREALQRLAE-YSWDEIDVASAEREIAELEAELER--------------LDASSDDLAA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1087 MSEELRGLKSEKQLYAQEANALKLEKGSLLSKLIEVETKITLLQEDQQklwsvnetlHLEKERVSEEKQVAEKRYQQEHR 1166
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE---------AAEDLARLELRALLEERFAAALG 760

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 568937376 1167 D------RESLVAEREKLLKEINAAQEELLKMHME 1195
Cdd:COG4913   761 DaverelRENLEERIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1310-1539 8.32e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 8.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1310 QTNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCASKALRK-------AELDMRQLQTSNSSLTKLL 1382
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAleqelaaLEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376 1383 EEIKTCRAitdseciqllhekESLAASERTLLAEKEELLSENRIITEkLSKQSEEVARLEMGLNEKITYLTSEKEVACQK 1462
Cdd:COG4942   100 EAQKEELA-------------ELLRALYRLGRQPPLALLLSPEDFLD-AVRRLQYLKYLAPARREQAEELRADLAELAAL 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568937376 1463 VAKLKKQQDSLLKEKSALELQNGDLLADRESSIKTIGDLRRKYDQEATNRRIVMQEKMKLLGNIDALKKELQERKKE 1539
Cdd:COG4942   166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 612-829 8.77e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 8.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  612 KSKLETAIASHQQAMEELKvsfsKGIGTDSAEFAELKTQIERLrldyqheiESLQSKQDSERSAHAKEMETMQAKLMKII 691
Cdd:COG4942    29 LEQLQQEIAELEKELAALK----KEEKALLKQLAALERRIAAL--------ARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  692 KEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKAN 771
Cdd:COG4942    97 AELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568937376  772 SEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQ 829
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 455-677 9.56e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 9.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  455 ETQTKLE--HARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKPP----- 527
Cdd:COG4942    24 EAEAELEqlQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEleaqk 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  528 GDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDV 607
Cdd:COG4942   104 EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568937376  608 IALwKSKLETAIASHQQAMEELKVSFSKgigtDSAEFAELKTQIERLrldyQHEIESLQSKQDSERSAHA 677
Cdd:COG4942   184 EEE-RAALEALKAERQKLLARLEKELAE----LAAELAELQQEAEEL----EALIARLEAEAAAAAERTP 244
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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