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Conserved domains on  [gi|568955981|ref|XP_006530660|]
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voltage-dependent P/Q-type calcium channel subunit alpha-1A isoform X11 [Mus musculus]

Protein Classification

voltage-dependent calcium channel subunit alpha family protein( domain architecture ID 13634489)

voltage-dependent calcium channel subunit alpha family protein, similar to human P/Q-type calcium channel subunit alpha-1A

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
1606-1863 2.59e-71

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 239.09  E-value: 2.59e-71
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1606 SPPFEYTIMAMIALNTIVLMMKFYGAS-VAYENALRVFNIVFTSLFSLECVLKVMAFGI-LNYFRDAWNIFDFVTVLGSI 1683
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPeEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1684 TDILVTEFGNnFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDGE 1763
Cdd:pfam00520   81 ISLVLSSVGS-LSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1764 DedsdedefQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGKpcdknsgiltadcGNEFAYFYFVSFIFLCSFLM 1843
Cdd:pfam00520  160 N--------PDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGK-------------GEFWAYIYFVSFIILGGFLL 218
                          250       260
                   ....*....|....*....|
gi 568955981  1844 LNLFVAVIMDNFEYLTRDSS 1863
Cdd:pfam00520  219 LNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
188-462 6.36e-68

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 229.46  E-value: 6.36e-68
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   188 WPPFEYMILATIIANCIVLALEQHLPDDDKTPmsERLDDTEPYFIGIFCFEAGIKIVALGFAFHkgsYLRNGWNVMDFVV 267
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLT--TVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVV 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   268 VLTGILATVGTE----FDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 343
Cdd:pfam00520   76 VLPSLISLVLSSvgslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   344 HTtcfeegtddiqgespapcgteepartcpngtkcqpyWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSNDASG 423
Cdd:pfam00520  156 KT------------------------------------WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG 199
                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 568955981   424 NTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVE 462
Cdd:pfam00520  200 EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
579-817 7.27e-57

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 197.87  E-value: 7.27e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   579 QAFYWTVLSLVALNTLCVAIVHYNQPEW-LSDFLYYAEFIFLGLFMSEMFIKMYGLG-TRPYFHSSFNCFDCGVIIGSIF 656
Cdd:pfam00520    2 RYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGfKKRYFRSPWNILDFVVVLPSLI 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   657 EVIWAVIKPGtsFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDE 736
Cdd:pfam00520   82 SLVLSSVGSL--SGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   737 G--TPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSqggvQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQE 814
Cdd:pfam00520  160 NpdNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDG----KGEFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTE 235

                   ...
gi 568955981   815 LTK 817
Cdd:pfam00520  236 RTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
1285-1516 2.68e-56

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 196.33  E-value: 2.68e-56
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1285 RYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHqgaYFRDLWNILDFIVVSG 1364
Cdd:pfam00520    2 RYFELFILLLILLNTIFLALETYFQPEEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVVVLP 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1365 ALVAFAFTGNSKGKDINtikSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKF 1444
Cdd:pfam00520   79 SLISLVLSSVGSLSGLR---VLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568955981  1445 fhctdeskeferdcrgkyllyeKNEVKARDREWkkyefHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFE 1516
Cdd:pfam00520  156 ----------------------KTWENPDNGRT-----NFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGE 200
Ca_chan_IQ pfam08763
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ...
1935-2012 8.34e-35

Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).


:

Pssm-ID: 462591  Cd Length: 77  Bit Score: 128.48  E-value: 8.34e-35
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568955981  1935 NSTLMALIRTALDIKIAKGGaDKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKA 2012
Cdd:pfam08763    1 TATLFALIRTSLKIKLAPAG-EMDQADAELRKIIKKIWPRLSQKTLDLLVPPPSDDEMTVGKIYAALLIQDYYRQNKA 77
GPHH pfam16905
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in ...
1872-1925 8.63e-30

Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in this short domain on voltage-dependent L-type calcium channel proteins in eukaryotes. The domain is closely associated with the IQ-domain, pfam08763.


:

Pssm-ID: 465306  Cd Length: 54  Bit Score: 113.13  E-value: 8.63e-30
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568955981  1872 EYVRVWAEYDPAACGRIHYKDMYSLLRVISPPLGLGKKCPHRVACKRLLRMDLP 1925
Cdd:pfam16905    1 EFVRVWAEYDPAATGRISYQDMYELLRRISPPLGFGKKCPARVAYKRLVRMNMP 54
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
2040-2454 1.85e-10

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 66.73  E-value: 1.85e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2040 EGGPSQNALPSTQLDPGGGLMAHEGGMKESPSWVtqrAQEMFQKTGTWSPERGPPIDMPNSQPNSQSVEMREMGTDGYSd 2119
Cdd:PHA03307   16 EGGEFFPRPPATPGDAADDLLSGSQGQLVSDSAE---LAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWS- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2120 sehylpmEGQTRAASMPRLPAENQRRRGRPRGNDlSTISDTSPMKRSASVLGPKARRldDYSLERVPPEENQRYH-QRRR 2198
Cdd:PHA03307   92 -------LSTLAPASPAREGSPTPPGPSSPDPPP-PTPPPASPPPSPAPDLSEMLRP--VGSPGPPPAASPPAAGaSPAA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2199 DRGHRTSERSLGRYTDVDtglgtdlSMTTQSGDLPSKDR--DQDRGRPKDRkhrphhhhHHHHHHPPAPDRDRYAQERPD 2276
Cdd:PHA03307  162 VASDAASSRQAALPLSSP-------EETARAPSSPPAEPppSTPPAAASPR--------PPRRSSPISASASSPAPAPGR 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2277 TGRARAREQRWSRSPSEGREhtthrQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPCTPRPLVSYSPAPRRPaarrmAGP 2356
Cdd:PHA03307  227 SAADDAGASSSDSSSSESSG-----CGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRE-----RSP 296
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2357 AAPPGGSPRGCRRAPRWPAHAPEGPRPRGADYTEPDSPRE-----PPGGAHDPAPRSPRTPRAAGCASPR---HGRRLPN 2428
Cdd:PHA03307  297 SPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSrgaavSPGPSPSRSPSPSRPPPPADPSSPRkrpRPSRAPS 376
                         410       420
                  ....*....|....*....|....*.
gi 568955981 2429 GYYAGHGAPRPRTARRGAHDAYSESE 2454
Cdd:PHA03307  377 SPAASAGRPTRRRARAAVAGRARRRD 402
PHA03247 super family cl33720
large tegument protein UL36; Provisional
895-1277 4.98e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 4.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  895 PTPYARPLRPDVKTHLDRPlVVDPQENR-------NNNTNKSRAPEALRP-TARPRESARDPDARRAWPGSPERAPGREG 966
Cdd:PHA03247 2571 PRPAPRPSEPAVTSRARRP-DAPPQSARprapvddRGDPRGPAPPSPLPPdTHAPDPPPPSPSPAANEPDPHPPPTVPPP 2649
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  967 PYGRESEPQQREHAPPREHAPWDAdterAKAGDAPRRHTHR---------------PVAEGEPRRHRARRRPGDEPDDRP 1031
Cdd:PHA03247 2650 ERPRDDPAPGRVSRPRRARRLGRA----AQASSPPQRPRRRaarptvgsltsladpPPPPPTPEPAPHALVSATPLPPGP 2725
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 1032 ERRPRPRDATR-----PARAADGEGDDGERKRRHRH---GPPAHDDrerrhrrrkenqgSGVPVSGPNLSTTRPIQQDLG 1103
Cdd:PHA03247 2726 AAARQASPALPaapapPAVPAGPATPGGPARPARPPttaGPPAPAP-------------PAAPAAGPPRRLTRPAVASLS 2792
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 1104 --RQDLPLAEDLDNMKNNKL------------ATGEP----ASPHDSLGHSGLPPSPAKIGNSTNPG------------- 1152
Cdd:PHA03247 2793 esRESLPSPWDPADPPAAVLapaaalppaaspAGPLPpptsAQPTAPPPPPGPPPPSLPLGGSVAPGgdvrrrppsrspa 2872
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 1153 --PALATNP------QNAASRRTPNNPGNPSNPGPPKTPenslivtnPSSTQPNSAKTARKPEHMAVEIPPacPPLNHTV 1224
Cdd:PHA03247 2873 akPAAPARPpvrrlaRPAVSRSTESFALPPDQPERPPQP--------QAPPPPQPQPQPPPPPQPQPPPPP--PPRPQPP 2942
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568955981 1225 VQVNKNANPDPLPKKEEEKKEEEEADPGEDG------PKPMPPYSSMfiLSTTNPLRRL 1277
Cdd:PHA03247 2943 LAPTTDPAGAGEPSGAVPQPWLGALVPGRVAvprfrvPQPAPSREAP--ASSTPPLTGH 2999
 
Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
1606-1863 2.59e-71

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 239.09  E-value: 2.59e-71
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1606 SPPFEYTIMAMIALNTIVLMMKFYGAS-VAYENALRVFNIVFTSLFSLECVLKVMAFGI-LNYFRDAWNIFDFVTVLGSI 1683
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPeEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1684 TDILVTEFGNnFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDGE 1763
Cdd:pfam00520   81 ISLVLSSVGS-LSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1764 DedsdedefQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGKpcdknsgiltadcGNEFAYFYFVSFIFLCSFLM 1843
Cdd:pfam00520  160 N--------PDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGK-------------GEFWAYIYFVSFIILGGFLL 218
                          250       260
                   ....*....|....*....|
gi 568955981  1844 LNLFVAVIMDNFEYLTRDSS 1863
Cdd:pfam00520  219 LNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
188-462 6.36e-68

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 229.46  E-value: 6.36e-68
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   188 WPPFEYMILATIIANCIVLALEQHLPDDDKTPmsERLDDTEPYFIGIFCFEAGIKIVALGFAFHkgsYLRNGWNVMDFVV 267
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLT--TVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVV 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   268 VLTGILATVGTE----FDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 343
Cdd:pfam00520   76 VLPSLISLVLSSvgslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   344 HTtcfeegtddiqgespapcgteepartcpngtkcqpyWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSNDASG 423
Cdd:pfam00520  156 KT------------------------------------WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG 199
                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 568955981   424 NTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVE 462
Cdd:pfam00520  200 EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
579-817 7.27e-57

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 197.87  E-value: 7.27e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   579 QAFYWTVLSLVALNTLCVAIVHYNQPEW-LSDFLYYAEFIFLGLFMSEMFIKMYGLG-TRPYFHSSFNCFDCGVIIGSIF 656
Cdd:pfam00520    2 RYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGfKKRYFRSPWNILDFVVVLPSLI 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   657 EVIWAVIKPGtsFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDE 736
Cdd:pfam00520   82 SLVLSSVGSL--SGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   737 G--TPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSqggvQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQE 814
Cdd:pfam00520  160 NpdNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDG----KGEFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTE 235

                   ...
gi 568955981   815 LTK 817
Cdd:pfam00520  236 RTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
1285-1516 2.68e-56

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 196.33  E-value: 2.68e-56
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1285 RYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHqgaYFRDLWNILDFIVVSG 1364
Cdd:pfam00520    2 RYFELFILLLILLNTIFLALETYFQPEEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVVVLP 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1365 ALVAFAFTGNSKGKDINtikSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKF 1444
Cdd:pfam00520   79 SLISLVLSSVGSLSGLR---VLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568955981  1445 fhctdeskeferdcrgkyllyeKNEVKARDREWkkyefHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFE 1516
Cdd:pfam00520  156 ----------------------KTWENPDNGRT-----NFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGE 200
Ca_chan_IQ pfam08763
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ...
1935-2012 8.34e-35

Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).


Pssm-ID: 462591  Cd Length: 77  Bit Score: 128.48  E-value: 8.34e-35
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568955981  1935 NSTLMALIRTALDIKIAKGGaDKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKA 2012
Cdd:pfam08763    1 TATLFALIRTSLKIKLAPAG-EMDQADAELRKIIKKIWPRLSQKTLDLLVPPPSDDEMTVGKIYAALLIQDYYRQNKA 77
GPHH pfam16905
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in ...
1872-1925 8.63e-30

Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in this short domain on voltage-dependent L-type calcium channel proteins in eukaryotes. The domain is closely associated with the IQ-domain, pfam08763.


Pssm-ID: 465306  Cd Length: 54  Bit Score: 113.13  E-value: 8.63e-30
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568955981  1872 EYVRVWAEYDPAACGRIHYKDMYSLLRVISPPLGLGKKCPHRVACKRLLRMDLP 1925
Cdd:pfam16905    1 EFVRVWAEYDPAATGRISYQDMYELLRRISPPLGFGKKCPARVAYKRLVRMNMP 54
Ca_chan_IQ smart01062
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ...
1990-2020 9.95e-11

Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).


Pssm-ID: 198130  Cd Length: 31  Bit Score: 58.39  E-value: 9.95e-11
                            10        20        30
                    ....*....|....*....|....*....|.
gi 568955981   1990 TDLTVGKIYAAMMIMEYYRQSKAKKLQAMRE 2020
Cdd:smart01062    1 DELTVGKIYAAMLIQDYFRQFKSRKEQELLG 31
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
2040-2454 1.85e-10

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 66.73  E-value: 1.85e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2040 EGGPSQNALPSTQLDPGGGLMAHEGGMKESPSWVtqrAQEMFQKTGTWSPERGPPIDMPNSQPNSQSVEMREMGTDGYSd 2119
Cdd:PHA03307   16 EGGEFFPRPPATPGDAADDLLSGSQGQLVSDSAE---LAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWS- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2120 sehylpmEGQTRAASMPRLPAENQRRRGRPRGNDlSTISDTSPMKRSASVLGPKARRldDYSLERVPPEENQRYH-QRRR 2198
Cdd:PHA03307   92 -------LSTLAPASPAREGSPTPPGPSSPDPPP-PTPPPASPPPSPAPDLSEMLRP--VGSPGPPPAASPPAAGaSPAA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2199 DRGHRTSERSLGRYTDVDtglgtdlSMTTQSGDLPSKDR--DQDRGRPKDRkhrphhhhHHHHHHPPAPDRDRYAQERPD 2276
Cdd:PHA03307  162 VASDAASSRQAALPLSSP-------EETARAPSSPPAEPppSTPPAAASPR--------PPRRSSPISASASSPAPAPGR 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2277 TGRARAREQRWSRSPSEGREhtthrQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPCTPRPLVSYSPAPRRPaarrmAGP 2356
Cdd:PHA03307  227 SAADDAGASSSDSSSSESSG-----CGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRE-----RSP 296
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2357 AAPPGGSPRGCRRAPRWPAHAPEGPRPRGADYTEPDSPRE-----PPGGAHDPAPRSPRTPRAAGCASPR---HGRRLPN 2428
Cdd:PHA03307  297 SPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSrgaavSPGPSPSRSPSPSRPPPPADPSSPRkrpRPSRAPS 376
                         410       420
                  ....*....|....*....|....*.
gi 568955981 2429 GYYAGHGAPRPRTARRGAHDAYSESE 2454
Cdd:PHA03307  377 SPAASAGRPTRRRARAAVAGRARRRD 402
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
2030-2446 2.92e-07

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 55.84  E-value: 2.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2030 QRMEPPSPTQEGG-PSQNALPSTQLDPGGGLMAHEGGMKESPSWV------TQRAQEMFQKTGTWSPERGPPidmpnSQP 2102
Cdd:COG5180    14 TVPIPPNAARPVLsPELWAAANNDAVSQGDRSALASSPTRPYARKifepldIKLALGKPQLPSVAEPEAYLD-----PAP 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2103 NSQSVEMREMGTDGYSDSehylpMEGQTRAASMPRLPAENQRRRGRPRgnDLSTISDTSPMKRSASVlgpkaRRLDDYSL 2182
Cdd:COG5180    89 PKSSPDTPEEQLGAPAGD-----LLVLPAAKTPELAAGALPAPAAAAA--LPKAKVTREATSASAGV-----ALAAALLQ 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2183 ERVPPEEnqryhQRRRDRGHRTSERSLGRYTDVDTG-LGTDLSMTTQSGDLPSKDRDQDRGRPKDrkhRPHHHHHHHHHH 2261
Cdd:COG5180   157 RSDPILA-----KDPDGDSASTLPPPAEKLDKVLTEpRDALKDSPEKLDRPKVEVKDEAQEEPPD---LTGGADHPRPEA 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2262 PPAPDRDRYAQERPDTGRARAREQRWSRSPSEGREhtthrqgSSSVSGSPAPSTSGTSTPRRGRRQLPQTPCTPRPLVSY 2341
Cdd:COG5180   229 ASSPKVDPPSTSEARSRPATVDAQPEMRPPADAKE-------RRRAAIGDTPAAEPPGLPVLEAGSEPQSDAPEAETARP 301
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2342 SPAPRRPAARRMAGPAAPPGGSPRGCRRAPRWPAHAPEGPRPRGADYTEPDSPREPPGGAHDPAPRSPRTPRAA------ 2415
Cdd:COG5180   302 IDVKGVASAPPATRPVRPPGGARDPGTPRPGQPTERPAGVPEAASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGssggdg 381
                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 568955981 2416 -------GCASPRHGRRLPNGYYAGHGAPRPRTARRGA 2446
Cdd:COG5180   382 apfqppnGAPQPGLGRRGAPGPPMGAGDLVQAALDGGG 419
PHA03247 PHA03247
large tegument protein UL36; Provisional
895-1277 4.98e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 4.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  895 PTPYARPLRPDVKTHLDRPlVVDPQENR-------NNNTNKSRAPEALRP-TARPRESARDPDARRAWPGSPERAPGREG 966
Cdd:PHA03247 2571 PRPAPRPSEPAVTSRARRP-DAPPQSARprapvddRGDPRGPAPPSPLPPdTHAPDPPPPSPSPAANEPDPHPPPTVPPP 2649
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  967 PYGRESEPQQREHAPPREHAPWDAdterAKAGDAPRRHTHR---------------PVAEGEPRRHRARRRPGDEPDDRP 1031
Cdd:PHA03247 2650 ERPRDDPAPGRVSRPRRARRLGRA----AQASSPPQRPRRRaarptvgsltsladpPPPPPTPEPAPHALVSATPLPPGP 2725
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 1032 ERRPRPRDATR-----PARAADGEGDDGERKRRHRH---GPPAHDDrerrhrrrkenqgSGVPVSGPNLSTTRPIQQDLG 1103
Cdd:PHA03247 2726 AAARQASPALPaapapPAVPAGPATPGGPARPARPPttaGPPAPAP-------------PAAPAAGPPRRLTRPAVASLS 2792
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 1104 --RQDLPLAEDLDNMKNNKL------------ATGEP----ASPHDSLGHSGLPPSPAKIGNSTNPG------------- 1152
Cdd:PHA03247 2793 esRESLPSPWDPADPPAAVLapaaalppaaspAGPLPpptsAQPTAPPPPPGPPPPSLPLGGSVAPGgdvrrrppsrspa 2872
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 1153 --PALATNP------QNAASRRTPNNPGNPSNPGPPKTPenslivtnPSSTQPNSAKTARKPEHMAVEIPPacPPLNHTV 1224
Cdd:PHA03247 2873 akPAAPARPpvrrlaRPAVSRSTESFALPPDQPERPPQP--------QAPPPPQPQPQPPPPPQPQPPPPP--PPRPQPP 2942
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568955981 1225 VQVNKNANPDPLPKKEEEKKEEEEADPGEDG------PKPMPPYSSMfiLSTTNPLRRL 1277
Cdd:PHA03247 2943 LAPTTDPAGAGEPSGAVPQPWLGALVPGRVAvprfrvPQPAPSREAP--ASSTPPLTGH 2999
Pro-rich pfam15240
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
2290-2439 7.88e-05

Proline-rich protein; This family includes several eukaryotic proline-rich proteins.


Pssm-ID: 464580 [Multi-domain]  Cd Length: 167  Bit Score: 45.41  E-value: 7.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  2290 SPSEGREHTTHRQGSSSVSGSPAPSTSGTSTPRRGrrqlPQTPCTPRPLVSyspaprrpaarrMAGPAAPPGGSPRGcrR 2369
Cdd:pfam15240   15 SAQSSSEDVSQEDSPSLISEEEGQSQQGGQGPQGP----PPGGFPPQPPAS------------DDPPGPPPPGGPQQ--P 76
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  2370 APRWPAHAPEGPRPRGADYTEPDSPREPPGGAHDPAPRSPRTPRAAGcaSPRHGRRLPNGYYAGHGAPRP 2439
Cdd:pfam15240   77 PPQGGKQKPQGPPPQGGPRPPPGKPQGPPPQGGNQQQGPPPPGKPQG--PPPQGGGPPPQGGNQQGPPPP 144
PLN03223 PLN03223
Polycystin cation channel protein; Provisional
721-814 9.49e-03

Polycystin cation channel protein; Provisional


Pssm-ID: 215637 [Multi-domain]  Cd Length: 1634  Bit Score: 41.47  E-value: 9.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  721 ALLGMQLFGGQFnfdegtppTNFDTFPAAIMTVFQILTGeDWNEVMYDgIKSQGGVQGgMVFSIYFIVLTLFGNYTLLNV 800
Cdd:PLN03223 1345 AFIGHVIFGNAS--------VHFSDMTDSINSLFENLLG-DITYFNED-LKNLTGLQF-VVGMIYFYSYNIFVFMILFNF 1413
                          90
                  ....*....|....*...
gi 568955981  801 FLAIAVDNL----ANAQE 814
Cdd:PLN03223 1414 LLAIICDAFgevkANAAE 1431
 
Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
1606-1863 2.59e-71

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 239.09  E-value: 2.59e-71
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1606 SPPFEYTIMAMIALNTIVLMMKFYGAS-VAYENALRVFNIVFTSLFSLECVLKVMAFGI-LNYFRDAWNIFDFVTVLGSI 1683
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPeEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1684 TDILVTEFGNnFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDGE 1763
Cdd:pfam00520   81 ISLVLSSVGS-LSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1764 DedsdedefQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGKpcdknsgiltadcGNEFAYFYFVSFIFLCSFLM 1843
Cdd:pfam00520  160 N--------PDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGK-------------GEFWAYIYFVSFIILGGFLL 218
                          250       260
                   ....*....|....*....|
gi 568955981  1844 LNLFVAVIMDNFEYLTRDSS 1863
Cdd:pfam00520  219 LNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
188-462 6.36e-68

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 229.46  E-value: 6.36e-68
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   188 WPPFEYMILATIIANCIVLALEQHLPDDDKTPmsERLDDTEPYFIGIFCFEAGIKIVALGFAFHkgsYLRNGWNVMDFVV 267
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLT--TVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVV 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   268 VLTGILATVGTE----FDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 343
Cdd:pfam00520   76 VLPSLISLVLSSvgslSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   344 HTtcfeegtddiqgespapcgteepartcpngtkcqpyWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSNDASG 423
Cdd:pfam00520  156 KT------------------------------------WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKG 199
                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 568955981   424 NTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVE 462
Cdd:pfam00520  200 EFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
579-817 7.27e-57

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 197.87  E-value: 7.27e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   579 QAFYWTVLSLVALNTLCVAIVHYNQPEW-LSDFLYYAEFIFLGLFMSEMFIKMYGLG-TRPYFHSSFNCFDCGVIIGSIF 656
Cdd:pfam00520    2 RYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGfKKRYFRSPWNILDFVVVLPSLI 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   657 EVIWAVIKPGtsFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDE 736
Cdd:pfam00520   82 SLVLSSVGSL--SGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKTWE 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   737 G--TPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSqggvQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQE 814
Cdd:pfam00520  160 NpdNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDG----KGEFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTE 235

                   ...
gi 568955981   815 LTK 817
Cdd:pfam00520  236 RTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
1285-1516 2.68e-56

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 196.33  E-value: 2.68e-56
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1285 RYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHqgaYFRDLWNILDFIVVSG 1364
Cdd:pfam00520    2 RYFELFILLLILLNTIFLALETYFQPEEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVVVLP 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1365 ALVAFAFTGNSKGKDINtikSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKF 1444
Cdd:pfam00520   79 SLISLVLSSVGSLSGLR---VLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKL 155
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568955981  1445 fhctdeskeferdcrgkyllyeKNEVKARDREWkkyefHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFE 1516
Cdd:pfam00520  156 ----------------------KTWENPDNGRT-----NFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGE 200
Ca_chan_IQ pfam08763
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ...
1935-2012 8.34e-35

Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).


Pssm-ID: 462591  Cd Length: 77  Bit Score: 128.48  E-value: 8.34e-35
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568955981  1935 NSTLMALIRTALDIKIAKGGaDKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKA 2012
Cdd:pfam08763    1 TATLFALIRTSLKIKLAPAG-EMDQADAELRKIIKKIWPRLSQKTLDLLVPPPSDDEMTVGKIYAALLIQDYYRQNKA 77
GPHH pfam16905
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in ...
1872-1925 8.63e-30

Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in this short domain on voltage-dependent L-type calcium channel proteins in eukaryotes. The domain is closely associated with the IQ-domain, pfam08763.


Pssm-ID: 465306  Cd Length: 54  Bit Score: 113.13  E-value: 8.63e-30
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568955981  1872 EYVRVWAEYDPAACGRIHYKDMYSLLRVISPPLGLGKKCPHRVACKRLLRMDLP 1925
Cdd:pfam16905    1 EFVRVWAEYDPAATGRISYQDMYELLRRISPPLGFGKKCPARVAYKRLVRMNMP 54
Ca_chan_IQ smart01062
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ...
1990-2020 9.95e-11

Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).


Pssm-ID: 198130  Cd Length: 31  Bit Score: 58.39  E-value: 9.95e-11
                            10        20        30
                    ....*....|....*....|....*....|.
gi 568955981   1990 TDLTVGKIYAAMMIMEYYRQSKAKKLQAMRE 2020
Cdd:smart01062    1 DELTVGKIYAAMLIQDYFRQFKSRKEQELLG 31
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
2040-2454 1.85e-10

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 66.73  E-value: 1.85e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2040 EGGPSQNALPSTQLDPGGGLMAHEGGMKESPSWVtqrAQEMFQKTGTWSPERGPPIDMPNSQPNSQSVEMREMGTDGYSd 2119
Cdd:PHA03307   16 EGGEFFPRPPATPGDAADDLLSGSQGQLVSDSAE---LAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWS- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2120 sehylpmEGQTRAASMPRLPAENQRRRGRPRGNDlSTISDTSPMKRSASVLGPKARRldDYSLERVPPEENQRYH-QRRR 2198
Cdd:PHA03307   92 -------LSTLAPASPAREGSPTPPGPSSPDPPP-PTPPPASPPPSPAPDLSEMLRP--VGSPGPPPAASPPAAGaSPAA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2199 DRGHRTSERSLGRYTDVDtglgtdlSMTTQSGDLPSKDR--DQDRGRPKDRkhrphhhhHHHHHHPPAPDRDRYAQERPD 2276
Cdd:PHA03307  162 VASDAASSRQAALPLSSP-------EETARAPSSPPAEPppSTPPAAASPR--------PPRRSSPISASASSPAPAPGR 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2277 TGRARAREQRWSRSPSEGREhtthrQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPCTPRPLVSYSPAPRRPaarrmAGP 2356
Cdd:PHA03307  227 SAADDAGASSSDSSSSESSG-----CGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRE-----RSP 296
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2357 AAPPGGSPRGCRRAPRWPAHAPEGPRPRGADYTEPDSPRE-----PPGGAHDPAPRSPRTPRAAGCASPR---HGRRLPN 2428
Cdd:PHA03307  297 SPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSrgaavSPGPSPSRSPSPSRPPPPADPSSPRkrpRPSRAPS 376
                         410       420
                  ....*....|....*....|....*.
gi 568955981 2429 GYYAGHGAPRPRTARRGAHDAYSESE 2454
Cdd:PHA03307  377 SPAASAGRPTRRRARAAVAGRARRRD 402
PKD_channel pfam08016
Polycystin cation channel; This family contains the cation channel region from group II of ...
1645-1856 6.01e-10

Polycystin cation channel; This family contains the cation channel region from group II of Transient receptor potential (TRP) channels, the TRPP subfamily, including PKD1, PKD2, PKD2L and mucolipin proteins.


Pssm-ID: 462341 [Multi-domain]  Cd Length: 225  Bit Score: 61.52  E-value: 6.01e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1645 VFTSLFSLECVLKVMAFGiLNYFRDAWNIFDFVTVLGSITDILvtefgnnfinLSFLRLFRAARLIKLLRQ--------- 1715
Cdd:pfam08016   19 VFFLYFVVEEILKIRKHR-PSYLRSVWNLLDLAIVILSVVLIV----------LNIYRDFLADRLIKSVEAspvtfidfd 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1716 -----GYTIRIL-----------LWTFVQSFK-----------ALPYVC---LLIAMLFFIYAIIGMQVFGNigidgede 1765
Cdd:pfam08016   88 rvaqlDNLYRIIlaflvfltwlkLFKVLRFNKtmslftktlsrAWKDLAgfaLMFVIFFFAYAQFGYLLFGT-------- 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  1766 dsdedefqitEHNNFRTFFQALMLLFRSATG-EAWHNImlsclsgKPCDKNSGILtadcgnefayfYFVSFIFLCSFLML 1844
Cdd:pfam08016  160 ----------QAPNFSNFVKSILTLFRTILGdFGYNEI-------FSGNRVLGPL-----------LFLTFVFLVIFILL 211
                          250
                   ....*....|..
gi 568955981  1845 NLFVAVIMDNFE 1856
Cdd:pfam08016  212 NLFLAIINDSYV 223
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
2035-2439 3.41e-08

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 59.41  E-value: 3.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2035 PSPTQEGGPSQNALPSTQLDPGGGLMAHEGGMKESPSW------VTQRAQEMFQKTGTWSPERGPP-IDMPNSQPNSQSV 2107
Cdd:PHA03307   53 VTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWslstlaPASPAREGSPTPPGPSSPDPPPpTPPPASPPPSPAP 132
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2108 EMREMGTDGYSDSEhylPMEGQTRAASMPRLPAENQRRRGRPRGNDLSTISDTSPMKRSASV-LGPKARRLDDYSLERVP 2186
Cdd:PHA03307  133 DLSEMLRPVGSPGP---PPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAePPPSTPPAAASPRPPRR 209
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2187 PEENQRYHQRRRDRGHRTSERSLGRYTDVDT---GLGTDLSMTTQSGDlPSKDRDQDRGRPKDRKHRPHHHHHHHHHHPP 2263
Cdd:PHA03307  210 SSPISASASSPAPAPGRSAADDAGASSSDSSsseSSGCGWGPENECPL-PRPAPITLPTRIWEASGWNGPSSRPGPASSS 288
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2264 APDRDRYAQERPDTGRARAREQRWSRSPSEGREHTThrQGSSSVSGSPAPSTSGTSTPRRGRRqlPQTPCTPRPlvsysp 2343
Cdd:PHA03307  289 SSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRES--SSSSTSSSSESSRGAAVSPGPSPSR--SPSPSRPPP------ 358
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2344 aprrpaarrmAGPAAPPGGSPRGCRRAPRWPAHAPEGPRPR-GADYTEPDSPREPPGGAhdPAPRSPRTPRAAGCASPRH 2422
Cdd:PHA03307  359 ----------PADPSSPRKRPRPSRAPSSPAASAGRPTRRRaRAAVAGRARRRDATGRF--PAGRPRPSPLDAGAASGAF 426
                         410       420
                  ....*....|....*....|
gi 568955981 2423 GRRLPNGYYAGH---GAPRP 2439
Cdd:PHA03307  427 YARYPLLTPSGEpwpGSPPP 446
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
2030-2446 2.92e-07

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 55.84  E-value: 2.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2030 QRMEPPSPTQEGG-PSQNALPSTQLDPGGGLMAHEGGMKESPSWV------TQRAQEMFQKTGTWSPERGPPidmpnSQP 2102
Cdd:COG5180    14 TVPIPPNAARPVLsPELWAAANNDAVSQGDRSALASSPTRPYARKifepldIKLALGKPQLPSVAEPEAYLD-----PAP 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2103 NSQSVEMREMGTDGYSDSehylpMEGQTRAASMPRLPAENQRRRGRPRgnDLSTISDTSPMKRSASVlgpkaRRLDDYSL 2182
Cdd:COG5180    89 PKSSPDTPEEQLGAPAGD-----LLVLPAAKTPELAAGALPAPAAAAA--LPKAKVTREATSASAGV-----ALAAALLQ 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2183 ERVPPEEnqryhQRRRDRGHRTSERSLGRYTDVDTG-LGTDLSMTTQSGDLPSKDRDQDRGRPKDrkhRPHHHHHHHHHH 2261
Cdd:COG5180   157 RSDPILA-----KDPDGDSASTLPPPAEKLDKVLTEpRDALKDSPEKLDRPKVEVKDEAQEEPPD---LTGGADHPRPEA 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2262 PPAPDRDRYAQERPDTGRARAREQRWSRSPSEGREhtthrqgSSSVSGSPAPSTSGTSTPRRGRRQLPQTPCTPRPLVSY 2341
Cdd:COG5180   229 ASSPKVDPPSTSEARSRPATVDAQPEMRPPADAKE-------RRRAAIGDTPAAEPPGLPVLEAGSEPQSDAPEAETARP 301
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2342 SPAPRRPAARRMAGPAAPPGGSPRGCRRAPRWPAHAPEGPRPRGADYTEPDSPREPPGGAHDPAPRSPRTPRAA------ 2415
Cdd:COG5180   302 IDVKGVASAPPATRPVRPPGGARDPGTPRPGQPTERPAGVPEAASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGssggdg 381
                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 568955981 2416 -------GCASPRHGRRLPNGYYAGHGAPRPRTARRGA 2446
Cdd:COG5180   382 apfqppnGAPQPGLGRRGAPGPPMGAGDLVQAALDGGG 419
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
2268-2454 3.40e-07

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 55.95  E-value: 3.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2268 DRYAQERPDTGRARAREQRWSRSPSEGREHTTHRQGSSSVSGSPAPSTSGTSTPrrGRRQLPQTPCTPRPlvsyspaprr 2347
Cdd:PHA03307  793 EAAFRRPGRLRRSGPAADAASRTASKRKSRSHTPDGGSESSGPARPPGAAARPP--PARSSESSKSKPAA---------- 860
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2348 paarrmagPAAPPGGSPRGCRRAPRWPAHAPEGPRPRGADYTEPDSPrePPGGAHDPAPRSPRTPRAAGCASPRHG-RRL 2426
Cdd:PHA03307  861 --------AGGRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAG--APAPRPRPAPRVKLGPMPPGGPDPRGGfRRV 930
                         170       180
                  ....*....|....*....|....*...
gi 568955981 2427 PNGYYagHGaPRPRTArrgAHDAYSESE 2454
Cdd:PHA03307  931 PPGDL--HT-PAPSAA---ALAAYCPPE 952
PHA03247 PHA03247
large tegument protein UL36; Provisional
2264-2419 3.40e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.02  E-value: 3.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2264 APDRDRYAQERPDTGRARAREQRWSRSPSEGREHTTHRQGSSsvsgsPAPSTSGTSTPRRGRRQL--------------- 2328
Cdd:PHA03247 2628 PPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARR-----LGRAAQASSPPQRPRRRAarptvgsltsladpp 2702
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2329 --PQTP-CTPRPLVSYSPAPRRPAARRMAGPAAPPGGSPRGCRRAPRWPA-HAPEGPRPRGADYTEPDSPREPPGGahdP 2404
Cdd:PHA03247 2703 ppPPTPePAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGgPARPARPPTTAGPPAPAPPAAPAAG---P 2779
                         170
                  ....*....|....*
gi 568955981 2405 APRSPRTPRAAGCAS 2419
Cdd:PHA03247 2780 PRRLTRPAVASLSES 2794
PHA03247 PHA03247
large tegument protein UL36; Provisional
2304-2453 3.55e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.02  E-value: 3.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2304 SSSVSGSPAPSTSGTSTPRRGRRQLPQTPCTPRPlvsyspaPRRPAARRMAGPAAPPGGSPRGCRRAPRWPAHAPEGPRP 2383
Cdd:PHA03247 2544 ASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRP-------SEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSP 2616
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2384 RGADYTEPDSPrePPGGAhdPAPRSPRTPRAAGCASPRHGRRLPngyyAGHGAPRPRTARRGAHDAYSES 2453
Cdd:PHA03247 2617 LPPDTHAPDPP--PPSPS--PAANEPDPHPPPTVPPPERPRDDP----APGRVSRPRRARRLGRAAQASS 2678
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
2264-2457 6.01e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 52.10  E-value: 6.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2264 APDRDRYAQERPDTGRARAREQRWSRSPSEGREHTTHRQGSSSVSGSPAPST-SGTSTPRRGRRQLPQTPCTPRPLVSYS 2342
Cdd:PHA03307   79 APANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPaPDLSEMLRPVGSPGPPPAASPPAAGAS 158
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2343 PAPRRPAARR---------MAGPAAPPGGSPRGCRRAPRWPAHAPEGPRPRG---ADYTEPDSPRePPGGAHDPAPRSP- 2409
Cdd:PHA03307  159 PAAVASDAASsrqaalplsSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSspiSASASSPAPA-PGRSAADDAGASSs 237
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568955981 2410 --RTPRAAGCAS--------PRHGR-RLPNGYYAGHGA--PRPRTARRGAHDAYSESEDDW 2457
Cdd:PHA03307  238 dsSSSESSGCGWgpenecplPRPAPiTLPTRIWEASGWngPSSRPGPASSSSSPRERSPSP 298
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
2264-2442 1.36e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.94  E-value: 1.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2264 APDRDRYAQERPDTGRARAREQRWSRSPsEGREHTTHRQGSSSVSGSPAPSTSGTSTPRrgRRQLPQTPCTPRPLvsysp 2343
Cdd:PHA03307  847 PARSSESSKSKPAAAGGRARGKNGRRRP-RPPEPRARPGAAAPPKAAAAAPPAGAPAPR--PRPAPRVKLGPMPP----- 918
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2344 aprrpaarrmAGPAappggsPRGC-RRAPRWPAHAPEGPRPRGADYTEP-------DSPREPPggAHDPAPRspRTPR-- 2413
Cdd:PHA03307  919 ----------GGPD------PRGGfRRVPPGDLHTPAPSAAALAAYCPPevvaelvDHPLFPE--PWRPALA--FDPEal 978
                         170       180       190
                  ....*....|....*....|....*....|..
gi 568955981 2414 ---AAGCASPRHGRRLPNGYYAGHGAPRPRTA 2442
Cdd:PHA03307  979 aeiAARCGGPPPRSGSAFGPLRASGPLRRRAA 1010
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
2274-2457 2.96e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 49.60  E-value: 2.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2274 RPDTGRARAREQRWSRSPSEGREHTTHR-QGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPCTPRPLVSYSPAPRRPAARR 2352
Cdd:PRK07764  587 VVGPAPGAAGGEGPPAPASSGPPEEAARpAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGG 666
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2353 MAGPAAPPGGSPRGCRRAPRWPAHAPEGPRPRGADYTEPdSPREPPGGAHDPAPRSPRTPRAAGCASPRHGRRLPNGYYA 2432
Cdd:PRK07764  667 DGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP-AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEP 745
                         170       180
                  ....*....|....*....|....*
gi 568955981 2433 GHGAPRPRTARRGAHDAYSESEDDW 2457
Cdd:PRK07764  746 DDPPDPAGAPAQPPPPPAPAPAAAP 770
PHA03247 PHA03247
large tegument protein UL36; Provisional
895-1277 4.98e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 4.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  895 PTPYARPLRPDVKTHLDRPlVVDPQENR-------NNNTNKSRAPEALRP-TARPRESARDPDARRAWPGSPERAPGREG 966
Cdd:PHA03247 2571 PRPAPRPSEPAVTSRARRP-DAPPQSARprapvddRGDPRGPAPPSPLPPdTHAPDPPPPSPSPAANEPDPHPPPTVPPP 2649
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  967 PYGRESEPQQREHAPPREHAPWDAdterAKAGDAPRRHTHR---------------PVAEGEPRRHRARRRPGDEPDDRP 1031
Cdd:PHA03247 2650 ERPRDDPAPGRVSRPRRARRLGRA----AQASSPPQRPRRRaarptvgsltsladpPPPPPTPEPAPHALVSATPLPPGP 2725
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 1032 ERRPRPRDATR-----PARAADGEGDDGERKRRHRH---GPPAHDDrerrhrrrkenqgSGVPVSGPNLSTTRPIQQDLG 1103
Cdd:PHA03247 2726 AAARQASPALPaapapPAVPAGPATPGGPARPARPPttaGPPAPAP-------------PAAPAAGPPRRLTRPAVASLS 2792
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 1104 --RQDLPLAEDLDNMKNNKL------------ATGEP----ASPHDSLGHSGLPPSPAKIGNSTNPG------------- 1152
Cdd:PHA03247 2793 esRESLPSPWDPADPPAAVLapaaalppaaspAGPLPpptsAQPTAPPPPPGPPPPSLPLGGSVAPGgdvrrrppsrspa 2872
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 1153 --PALATNP------QNAASRRTPNNPGNPSNPGPPKTPenslivtnPSSTQPNSAKTARKPEHMAVEIPPacPPLNHTV 1224
Cdd:PHA03247 2873 akPAAPARPpvrrlaRPAVSRSTESFALPPDQPERPPQP--------QAPPPPQPQPQPPPPPQPQPPPPP--PPRPQPP 2942
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568955981 1225 VQVNKNANPDPLPKKEEEKKEEEEADPGEDG------PKPMPPYSSMfiLSTTNPLRRL 1277
Cdd:PHA03247 2943 LAPTTDPAGAGEPSGAVPQPWLGALVPGRVAvprfrvPQPAPSREAP--ASSTPPLTGH 2999
PHA03381 PHA03381
tegument protein VP22; Provisional
2289-2425 5.80e-05

tegument protein VP22; Provisional


Pssm-ID: 177618 [Multi-domain]  Cd Length: 290  Bit Score: 47.70  E-value: 5.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2289 RSPSEgREHTTHRQGS----SSVSGSPAPSTSGTSTPR-RGRRQLPQTPCTPRPLVSYSPAPRRPAARRMAGPAAPPGGS 2363
Cdd:PHA03381    5 RSPRP-KPHGTDEVEAdvyyDFISPDASPARVSFEEPAdRARRGAGQARGRSQAERRFHHYDEARADYPYYTGSSSEDER 83
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568955981 2364 PRGCRRaPRWPAHAPEGPRP---RGAdyTEPDSPREPPGGAHDPAPRSPRTPRAagcASPRHGRR 2425
Cdd:PHA03381   84 PADPRP-SRRPHAQPEASGPgpaRGA--RGPAGSRGRGRRAESPSPRDPPNPKG---ASAPRGRK 142
Pro-rich pfam15240
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
2290-2439 7.88e-05

Proline-rich protein; This family includes several eukaryotic proline-rich proteins.


Pssm-ID: 464580 [Multi-domain]  Cd Length: 167  Bit Score: 45.41  E-value: 7.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  2290 SPSEGREHTTHRQGSSSVSGSPAPSTSGTSTPRRGrrqlPQTPCTPRPLVSyspaprrpaarrMAGPAAPPGGSPRGcrR 2369
Cdd:pfam15240   15 SAQSSSEDVSQEDSPSLISEEEGQSQQGGQGPQGP----PPGGFPPQPPAS------------DDPPGPPPPGGPQQ--P 76
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  2370 APRWPAHAPEGPRPRGADYTEPDSPREPPGGAHDPAPRSPRTPRAAGcaSPRHGRRLPNGYYAGHGAPRP 2439
Cdd:pfam15240   77 PPQGGKQKPQGPPPQGGPRPPPGKPQGPPPQGGNQQQGPPPPGKPQG--PPPQGGGPPPQGGNQQGPPPP 144
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
2274-2444 9.83e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.86  E-value: 9.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2274 RPDTGRARAREQRWS------RSPSE--------GREHTTHRQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPCTPRPL- 2338
Cdd:PHA03307  738 RYSPRRARARASAWDitdalfSNPSLvpaklaeaLALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTAs 817
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2339 VSYSPAPRRPAARRMAGPAAPPG--GSPRGCRRAP-RWPAHAPEGPRPRGADYTEPDSPREP---------PGGAHDPAP 2406
Cdd:PHA03307  818 KRKSRSHTPDGGSESSGPARPPGaaARPPPARSSEsSKSKPAAAGGRARGKNGRRRPRPPEPrarpgaaapPKAAAAAPP 897
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 568955981 2407 RSPRTPRAAGCASPRHGRRLPNGyyaghgaPRPRTARR 2444
Cdd:PHA03307  898 AGAPAPRPRPAPRVKLGPMPPGG-------PDPRGGFR 928
PRK12678 PRK12678
transcription termination factor Rho; Provisional
871-1063 1.03e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 47.59  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  871 TSEMRKQNLLAS-REALYG---DAAERWPTPYARPLRPDVKTHLDRPLVVDPQENRnnNTNKSRAPEALRPTARPRESAR 946
Cdd:PRK12678   43 TSGMRKGELIAAiKEARGGgaaAAAATPAAPAAAARRAARAAAAARQAEQPAAEAA--AAKAEAAPAARAAAAAAAEAAS 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  947 DPDARRAWPGSPERAPGREGPYGRESEPQQREHAPPREHApwDADTERAKAGDAPRRHTHRPVAEGEPrrhrarrRPGDE 1026
Cdd:PRK12678  121 APEAAQARERRERGEAARRGAARKAGEGGEQPATEARADA--AERTEEEERDERRRRGDREDRQAEAE-------RGERG 191
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 568955981 1027 PDDRPERRPRPRDATRPARAADGEGDDGERKRRHRHG 1063
Cdd:PRK12678  192 RREERGRDGDDRDRRDRREQGDRREERGRRDGGDRRG 228
PHA03378 PHA03378
EBNA-3B; Provisional
2313-2446 3.98e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 45.83  E-value: 3.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2313 PSTSGTSTPRR-----GRRQLPqtPCTPRPlvsyspaprrpaarrMAGPAAPPGGS--PRGCRRAPRWPAHAPEGPRPRG 2385
Cdd:PHA03378  676 PSPTGANTMLPiqwapGTMQPP--PRAPTP---------------MRPPAAPPGRAqrPAAATGRARPPAAAPGRARPPA 738
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568955981 2386 ADYTEPDSPREPPGGAHDP--APRSPRTPRAA-GCASPRHGRRLPngyyaghgaPRPRTARRGA 2446
Cdd:PHA03378  739 AAPGRARPPAAAPGRARPPaaAPGRARPPAAApGAPTPQPPPQAP---------PAPQQRPRGA 793
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
2353-2454 6.02e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.36  E-value: 6.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2353 MAGPAAPPGGSPRGCRRAPRWPAHAPEGPRPRGADytePDSPREPPGGAHDPAPRSPRTPRAAGCASPRHGRRLPNGyyA 2432
Cdd:PRK07764  387 VAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAA---APAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAA--A 461
                          90       100
                  ....*....|....*....|..
gi 568955981 2433 GHGAPRPRTARRGAHDAYSESE 2454
Cdd:PRK07764  462 PSAQPAPAPAAAPEPTAAPAPA 483
PHA03381 PHA03381
tegument protein VP22; Provisional
2353-2446 8.88e-04

tegument protein VP22; Provisional


Pssm-ID: 177618 [Multi-domain]  Cd Length: 290  Bit Score: 43.85  E-value: 8.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2353 MAGPAAPPGGSPRGCRRAPRWPAHA-PEGPR------PRGADY-------TEPDSPREPP--------GGAHDP----AP 2406
Cdd:PHA03381   29 DASPARVSFEEPADRARRGAGQARGrSQAERrfhhydEARADYpyytgssSEDERPADPRpsrrphaqPEASGPgparGA 108
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 568955981 2407 RSPRTPRAAGCASPRHGRRLPNgyyAGHGAPRPRtARRGA 2446
Cdd:PHA03381  109 RGPAGSRGRGRRAESPSPRDPP---NPKGASAPR-GRKSA 144
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
2264-2421 1.14e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.21  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2264 APDRDRYAQERPDTGRARAREQRWSRSPSEGREHTTHRQGSSSVSGSPAPSTSGTSTPRRGRRQ-LPQTPCTPRPLVSYS 2342
Cdd:PRK07764  635 APAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPaQPAPAPAATPPAGQA 714
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568955981 2343 PAPRRPAARRMAGPAAPPGGSPRGcrraPRWPAHAPEGPRPRGADYTEPDSPREPPGGAhdPAPRSPRTPRAAGCASPR 2421
Cdd:PRK07764  715 DDPAAQPPQAAQGASAPSPAADDP----VPLPPEPDDPPDPAGAPAQPPPPPAPAPAAA--PAAAPPPSPPSEEEEMAE 787
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
2354-2446 2.05e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.44  E-value: 2.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2354 AGPAAPPGGSPRGCRRAPRWPAHAPE---GPRPRGADYTEPDSPREPPGGAHDPAPRSPRTPRAAGCASP-RHGRRLPNG 2429
Cdd:PRK07764  405 APAAAPAPAAAAPAAAAAPAPAAAPQpapAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPePTAAPAPAP 484
                          90
                  ....*....|....*..
gi 568955981 2430 YYAGHGAPRPRTARRGA 2446
Cdd:PRK07764  485 PAAPAPAAAPAAPAAPA 501
PHA03247 PHA03247
large tegument protein UL36; Provisional
880-1265 2.46e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 2.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  880 LASREAlyGDAAERWPtPYARPLRPDVKTHLDRPlvvdpqenrnnntnksrAPEALRPTARPREsaRDPDARrAWPGSPe 959
Cdd:PHA03247 2543 LASDDA--GDPPPPLP-PAAPPAAPDRSVPPPRP-----------------APRPSEPAVTSRA--RRPDAP-PQSARP- 2598
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  960 RAPGreGPYGRESEPQQREHAPPREHAP-WDADTERAKAGDAPRRHthrPVAEGEPRRHRARRRPGDEPDDRPerrprpr 1038
Cdd:PHA03247 2599 RAPV--DDRGDPRGPAPPSPLPPDTHAPdPPPPSPSPAANEPDPHP---PPTVPPPERPRDDPAPGRVSRPRR------- 2666
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 1039 dATRPARAADGEGDdgERKRRHRHGPPAHddrerrhrrrkenqgsgvpvsGPNLSTTRPIQQDlgrqdlplaedldnmkn 1118
Cdd:PHA03247 2667 -ARRLGRAAQASSP--PQRPRRRAARPTV---------------------GSLTSLADPPPPP----------------- 2705
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 1119 nklATGEPAsPHDSLGHSGLPPSPAKIGNSTNPGPALATNPQNAASRRTPNNPGNPSNPGPPKTPENSLIVTNPSSTQPn 1198
Cdd:PHA03247 2706 ---PTPEPA-PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPP- 2780
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568955981 1199 sAKTARKPEHMAVEIPPACP----PLNHTVVQVNKNA--NPDPLPKKEEEKKEEEEADPGEDGPKPMPPYSSM 1265
Cdd:PHA03247 2781 -RRLTRPAVASLSESRESLPspwdPADPPAAVLAPAAalPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
2354-2446 2.95e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.05  E-value: 2.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2354 AGPAAPPGGSPRGCRRAPRWPAHAPEGPRPRGADYTEPDSPREPPGGAHDPAPRSPRTPRAAGcASPRHGRRLPNGYYAG 2433
Cdd:PRK07764  586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVA-APEHHPKHVAVPDASD 664
                          90
                  ....*....|...
gi 568955981 2434 HGAPRPRTARRGA 2446
Cdd:PRK07764  665 GGDGWPAKAGGAA 677
PHA03247 PHA03247
large tegument protein UL36; Provisional
2244-2445 3.57e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 3.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2244 PKDRKHRPHHHHHHHHHHPPAPDRDRYAQ-----ERPDTGRARAREQRWSrSPSEGREHTTHRQGSSSVSGS-------- 2310
Cdd:PHA03247 2628 PPSPSPAANEPDPHPPPTVPPPERPRDDPapgrvSRPRRARRLGRAAQAS-SPPQRPRRRAARPTVGSLTSLadpppppp 2706
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2311 -----PAPSTSGTSTP---RRGRRQLPQTPCTPRP------LVSYSPAPRRPAARRMAG------PAAPPGGSPRGCRRA 2370
Cdd:PHA03247 2707 tpepaPHALVSATPLPpgpAAARQASPALPAAPAPpavpagPATPGGPARPARPPTTAGppapapPAAPAAGPPRRLTRP 2786
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2371 PRWPAHAPEGPRPRGADYTEPDSPREPPGGA----HDPAPRSPRTPRAAGCASPRHGRRLPNGYYAGHG-APRPRTARRG 2445
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAAlppaASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSvAPGGDVRRRP 2866
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
2274-2456 3.91e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 3.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2274 RPDTGRARAREQRWSRSPSEGREHTTHRQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPCTPRPLVSYSPAPRRPAARRM 2353
Cdd:PRK07764  601 PAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAA 680
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2354 AGPAAPPGGSPRGCRRA-------PRWPAHAPEGPRPRGADYTEPDSPREPPGGAHDPAPRsPRTPRAAGCASPrhgrrl 2426
Cdd:PRK07764  681 PPPAPAPAAPAAPAGAApaqpapaPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPL-PPEPDDPPDPAG------ 753
                         170       180       190
                  ....*....|....*....|....*....|
gi 568955981 2427 PNGYYAGHGAPRPRTARRGAHDAYSESEDD 2456
Cdd:PRK07764  754 APAQPPPPPAPAPAAAPAAAPPPSPPSEEE 783
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
2288-2413 3.96e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 42.75  E-value: 3.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2288 SRSPSEGREHTTHRQGSSSVSGSPA----PST--------SGTSTPRRGRRqlPQTPCTPRPLVSYSPaprrpaarrmag 2355
Cdd:PTZ00449  540 SDEPKEGGKPGETKEGEVGKKPGPAkehkPSKiptlskkpEFPKDPKHPKD--PEEPKKPKRPRSAQR------------ 605
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568955981 2356 PAAPPggSPR-----GCRRAPRWPaHAPEGPRpRGADYTEPDSPREPPGGAHDPAPRSPRTPR 2413
Cdd:PTZ00449  606 PTRPK--SPKlpellDIPKSPKRP-ESPKSPK-RPPPPQRPSSPERPEGPKIIKSPKPPKSPK 664
PHA03247 PHA03247
large tegument protein UL36; Provisional
2088-2427 4.04e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 4.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2088 SPERGPPIDMPNSQPNSQSVEMREMGTDgysdsehyLPMEGQTraasmPRLPAENqrrRGRPRGNDLSTIS--DTSPMKR 2165
Cdd:PHA03247 2563 APDRSVPPPRPAPRPSEPAVTSRARRPD--------APPQSAR-----PRAPVDD---RGDPRGPAPPSPLppDTHAPDP 2626
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2166 SASVLGPKARRLDD-YSLERVPPEENQRYHQRRRDRGHRTSeRSLGRytdvdtglGTDLSMTTQsGDLPSKDRD-----Q 2239
Cdd:PHA03247 2627 PPPSPSPAANEPDPhPPPTVPPPERPRDDPAPGRVSRPRRA-RRLGR--------AAQASSPPQ-RPRRRAARPtvgslT 2696
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2240 DRGRPKDRKHRPHHHHHHHHHHPPAPdrdryaqERPDTGRARAREQRWSRSPSEGREHTTHRQGSSSVSGSPAPSTSGTS 2319
Cdd:PHA03247 2697 SLADPPPPPPTPEPAPHALVSATPLP-------PGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAP 2769
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2320 TPRRGRRQLPQtPCTPRPLV-----------SYSPAPRRPAARRMAGPAAPPGGSPRGCRRAPRWPAHAPEGPRPrgady 2388
Cdd:PHA03247 2770 APPAAPAAGPP-RRLTRPAVaslsesreslpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP----- 2843
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 568955981 2389 tEPDSPREPPGGAHDP----APRSPRTPRAAGCASPRH--GRRLP 2427
Cdd:PHA03247 2844 -GPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARppVRRLA 2887
PHA03378 PHA03378
EBNA-3B; Provisional
2291-2420 4.69e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 42.36  E-value: 4.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2291 PSEGREHTTHRQGSSSVSGSPAPSTSGTSTPRR---GRRQLPQTPCTPRPLVSySPAPRRPAARRMAGPAAPPGGSPRGC 2367
Cdd:PHA03378  676 PSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAappGRAQRPAAATGRARPPA-AAPGRARPPAAAPGRARPPAAAPGRA 754
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568955981 2368 RRaprwPAHAPEGPRPRGADYTEPdSPREPPGGAhdPAPRspRTPRAAGCASP 2420
Cdd:PHA03378  755 RP----PAAAPGRARPPAAAPGAP-TPQPPPQAP--PAPQ--QRPRGAPTPQP 798
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
2271-2421 5.91e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.90  E-value: 5.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2271 AQERPDTGRARAREQRWSRSPSEGREHTTHRQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPCTPRPlvSYSPAPRRPAA 2350
Cdd:PRK07764  626 APAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAA--PAGAAPAQPAP 703
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568955981 2351 RRMAGPAAPPGGSPRGcrrAPRWPAHAPEGPRPRGADY----TEPDSPREPPGGAHDPAPRSPRTPRAAGCASPR 2421
Cdd:PRK07764  704 APAATPPAGQADDPAA---QPPQAAQGASAPSPAADDPvplpPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPP 775
dnaA PRK14086
chromosomal replication initiator protein DnaA;
2281-2439 7.68e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 41.35  E-value: 7.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2281 RAREQRWSRSPSEGREHTTHRQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPCT-PRPLVSYSPAPRRPAARRMAGPAAP 2359
Cdd:PRK14086  104 RTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPAYPAYQQRPEPGAwPRAADDYGWQQQRLGFPPRAPYASP 183
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981 2360 PGGSPRGCRRAPRWPAHAPEGPRPR------GADYTEP-----DSPREPPGGAHDPApRSPRTPRAAGCASPRHGRRLPn 2428
Cdd:PRK14086  184 ASYAPEQERDREPYDAGRPEYDQRRrdydhpRPDWDRPrrdrtDRPEPPPGAGHVHR-GGPGPPERDDAPVVPIRPSAP- 261
                         170
                  ....*....|.
gi 568955981 2429 GYYAGHGAPRP 2439
Cdd:PRK14086  262 GPLAAQPAPAP 272
PKD_channel pfam08016
Polycystin cation channel; This family contains the cation channel region from group II of ...
607-804 9.02e-03

Polycystin cation channel; This family contains the cation channel region from group II of Transient receptor potential (TRP) channels, the TRPP subfamily, including PKD1, PKD2, PKD2L and mucolipin proteins.


Pssm-ID: 462341 [Multi-domain]  Cd Length: 225  Bit Score: 40.34  E-value: 9.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   607 LSDFLYYAEFIFLGL---FMSEMFIKmYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPG----------------T 667
Cdd:pfam08016    6 RSLFILLCEIVFVVFflyFVVEEILK-IRKHRPSYLRSVWNLLDLAIVILSVVLIVLNIYRDFladrliksveaspvtfI 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981   668 SFG------------ISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFnfd 735
Cdd:pfam08016   85 DFDrvaqldnlyriiLAFLVFLTWLKLFKVLRFNKTMSLFTKTLSRAWKDLAGFALMFVIFFFAYAQFGYLLFGTQA--- 161
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568955981   736 egtppTNFDTFPAAIMTVFQILTG-EDWNEVMYdgiksqggvqGGMVFSI-YFIVLTLFGNYTLLNVFLAI 804
Cdd:pfam08016  162 -----PNFSNFVKSILTLFRTILGdFGYNEIFS----------GNRVLGPlLFLTFVFLVIFILLNLFLAI 217
PLN03223 PLN03223
Polycystin cation channel protein; Provisional
721-814 9.49e-03

Polycystin cation channel protein; Provisional


Pssm-ID: 215637 [Multi-domain]  Cd Length: 1634  Bit Score: 41.47  E-value: 9.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568955981  721 ALLGMQLFGGQFnfdegtppTNFDTFPAAIMTVFQILTGeDWNEVMYDgIKSQGGVQGgMVFSIYFIVLTLFGNYTLLNV 800
Cdd:PLN03223 1345 AFIGHVIFGNAS--------VHFSDMTDSINSLFENLLG-DITYFNED-LKNLTGLQF-VVGMIYFYSYNIFVFMILFNF 1413
                          90
                  ....*....|....*...
gi 568955981  801 FLAIAVDNL----ANAQE 814
Cdd:PLN03223 1414 LLAIICDAFgevkANAAE 1431
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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