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Conserved domains on  [gi|755566885|ref|XP_011246883|]
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histone demethylase UTY isoform X3 [Mus musculus]

Protein Classification

KDM6 family histone demethylase( domain architecture ID 18639591)

KDM6 family histone demethylase, similar to lysine-specific demethylase 6A (KDM6A), also called UTX (ubiquitously-transcribed TPR protein on the X chromosome) that specifically demethylates 'Lys-27' of histone H3, and UTY (ubiquitously-transcribed TPR protein on the Y chromosome) that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3

CATH:  1.25.40.10|2.60.120.10
EC:  1.14.11.-
Gene Ontology:  GO:0005515|GO:0032452|GO:0031490|GO:0046872
PubMed:  26059336|21153002|10517866|30708253|22404999|11165500|14697267|19478949
SCOP:  4001344|3001825

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 966-1074 2.68e-33

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


:

Pssm-ID: 396791  Cd Length: 114  Bit Score: 124.72  E-value: 2.68e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   966 QLCMKVPGSRIPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNN-------LNFLMSSWWPnlEDLYEANV 1038
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 755566885  1039 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNITWNV 1074
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
221-458 2.52e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 103.55  E-value: 2.52e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  221 VEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMdligdnttkERY--AIQYLQKSLEEDPN 298
Cdd:COG0457     8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELD--PDDAEA--LYNLGLAYLRL---------GRYeeALADYEQALELDPD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  299 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 378
Cdd:COG0457    75 DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIAL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  379 ESCNQPQDAIKCYlNAARSKSCNNTSALTSRIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQ 458
Cdd:COG0457   155 EKLGRYEEALELL-EKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLAL 233
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 64-296 6.13e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.59  E-value: 6.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   64 LLNKAIHFYESLIVKAEGKVESdfFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkafqnhfwwwkitrevwklllrkf 143
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEA--LRLLAEIYEQEGDWEKAIEVLERLLKLGPE-------------------------- 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  144 rNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSVE 222
Cdd:COG2956   143 -NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARA---LLLLAELYLEQGDYEEAIAALERALeQD-----PDYLP 213

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755566885  223 IQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQV--KATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEED 296
Cdd:COG2956   214 ALPRLAELYEKLGDPEEALELLRKALELDPSDDLLlaLADLLERKE--------------GLEAALALLERQLRRH 275
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 932-996 6.10e-04

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


:

Pssm-ID: 214721  Cd Length: 58  Bit Score: 39.16  E-value: 6.10e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755566885    932 QLHELTKLPafvrvvSAGNLLSHVGYTILGMNSVQLC-MKVPGSRIPGHQENNNfcSVNINIGPGD 996
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVGPYLyMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
 
Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 966-1074 2.68e-33

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


Pssm-ID: 396791  Cd Length: 114  Bit Score: 124.72  E-value: 2.68e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   966 QLCMKVPGSRIPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNN-------LNFLMSSWWPnlEDLYEANV 1038
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 755566885  1039 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNITWNV 1074
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
221-458 2.52e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 103.55  E-value: 2.52e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  221 VEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMdligdnttkERY--AIQYLQKSLEEDPN 298
Cdd:COG0457     8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELD--PDDAEA--LYNLGLAYLRL---------GRYeeALADYEQALELDPD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  299 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 378
Cdd:COG0457    75 DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIAL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  379 ESCNQPQDAIKCYlNAARSKSCNNTSALTSRIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQ 458
Cdd:COG0457   155 EKLGRYEEALELL-EKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLAL 233
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 64-296 6.13e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.59  E-value: 6.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   64 LLNKAIHFYESLIVKAEGKVESdfFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkafqnhfwwwkitrevwklllrkf 143
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEA--LRLLAEIYEQEGDWEKAIEVLERLLKLGPE-------------------------- 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  144 rNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSVE 222
Cdd:COG2956   143 -NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARA---LLLLAELYLEQGDYEEAIAALERALeQD-----PDYLP 213

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755566885  223 IQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQV--KATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEED 296
Cdd:COG2956   214 ALPRLAELYEKLGDPEEALELLRKALELDPSDDLLlaLADLLERKE--------------GLEAALALLERQLRRH 275
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 144-391 6.13e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 6.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   144 RNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGfMFKM----------------NTDYESSLKHFQ 207
Cdd:TIGR02917  361 DDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAA---RTQLG-ISKLsqgdpseaiadletaaQLDPELGRADLL 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   208 LAL-------IDCNVCTLSSVE--------IQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKATVLQQlgwmhhNM 272
Cdd:TIGR02917  437 LILsylrsgqFDKALAAAKKLEkkqpdnasLHNLLGAIYLGKGDLAKAREAFEKALSIE--PDFFPAAANLA------RI 508

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   273 DLIGDNTTKeryAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMD 352
Cdd:TIGR02917  509 DIQEGNPDD---AIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKK 585

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 755566885   353 ALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCY 391
Cdd:TIGR02917  586 ALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 65-302 5.71e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 5.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885    65 LNKAIHFYESLIVKAEGKVESdfFCQLGHFNLLLEDYSKALSSYQRYYSLQTDYWKAFQ---NHFWWWKITREVWKLLLR 141
Cdd:TIGR02917  617 LNKAVSSFKKLLALQPDSALA--LLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIglaQLLLAAKRTESAKKIAKS 694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   142 ---KFRNAAFLYGL-GLVYFYYNAFQWAIRAFQEVLYVDP---NFCRAKEIHLRLGFMFKMNTDYESSLKhfqlalIDCN 214
Cdd:TIGR02917  695 lqkQHPKAALGFELeGDLYLRQKDYPAAIQAYRKALKRAPssqNAIKLHRALLASGNTAEAVKTLEAWLK------THPN 768

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   215 vctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQvkATVLQQLGWMHHNMdligdnttKERYAIQYLQKSLE 294
Cdd:TIGR02917  769 -----DAVLRTALAELYLAQKDYDKAIKHYQTVVKKA--PDN--AVVLNNLAWLYLEL--------KDPRALEYAERALK 831


                   ....*...
gi 755566885   295 EDPNSGQS 302
Cdd:TIGR02917  832 LAPNIPAI 839
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 145-210 2.81e-04

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 43.52  E-value: 2.81e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755566885  145 NAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRakeIHLRLGFMFKMNTDYESSLKHFQLAL 210
Cdd:NF040959  138 NFNLNYRLGLALDGLGQYDKAIEAFQKALELDPNEIK---YHQAIGFMYVQKGDHETAAEHFKKAM 200
TPR_1 pfam00515
Tetratricopeptide repeat;
146-179 4.33e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 4.33e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 755566885   146 AAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNF 179
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 932-996 6.10e-04

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


Pssm-ID: 214721  Cd Length: 58  Bit Score: 39.16  E-value: 6.10e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755566885    932 QLHELTKLPafvrvvSAGNLLSHVGYTILGMNSVQLC-MKVPGSRIPGHQENNNfcSVNINIGPGD 996
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVGPYLyMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
 
Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 966-1074 2.68e-33

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


Pssm-ID: 396791  Cd Length: 114  Bit Score: 124.72  E-value: 2.68e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   966 QLCMKVPGSRIPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNN-------LNFLMSSWWPnlEDLYEANV 1038
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 755566885  1039 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNITWNV 1074
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
221-458 2.52e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 103.55  E-value: 2.52e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  221 VEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMdligdnttkERY--AIQYLQKSLEEDPN 298
Cdd:COG0457     8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELD--PDDAEA--LYNLGLAYLRL---------GRYeeALADYEQALELDPD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  299 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 378
Cdd:COG0457    75 DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIAL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  379 ESCNQPQDAIKCYlNAARSKSCNNTSALTSRIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQ 458
Cdd:COG0457   155 EKLGRYEEALELL-EKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLAL 233
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 146-396 2.55e-24

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 104.04  E-value: 2.55e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  146 AAFLYG---LGLVYFYYNAFQWAIRAFQEVLYVDPNfcrAKEIHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSV 221
Cdd:COG2956     5 VAAALGwyfKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQKLLeRD-----PDRA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  222 EIQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQVK---ATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEEDPN 298
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALrllAEIYEQEG--------------DWEKAIEVLERLLKLGPE 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  299 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 378
Cdd:COG2956   143 NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                         250
                  ....*....|....*...
gi 755566885  379 ESCNQPQDAIKCYLNAAR 396
Cdd:COG2956   223 EKLGDPEEALELLRKALE 240
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 187-463 1.38e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 99.03  E-value: 1.38e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  187 LRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslpsQVKATVLQQL 265
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALeLD-----PETVEAHLALGNLYRRRGEYDRAIRIHQKLLERD----PDRAEALLEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  266 GWMHHNMDLigdnttKERyAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQ 345
Cdd:COG2956    83 AQDYLKAGL------LDR-AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  346 QQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLNAARSKScNNTSALtSRIKFLQAQLCNLPQ--S 423
Cdd:COG2956   156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDP-DYLPAL-PRLAELYEKLGDPEEalE 233

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 755566885  424 SLQNKTKLLPSIEEAWSLpipAELTSRQGAMNTAQQSVSD 463
Cdd:COG2956   234 LLRKALELDPSDDLLLAL---ADLLERKEGLEAALALLER 270
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
145-335 1.38e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 89.68  E-value: 1.38e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  145 NAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSVEI 223
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA---LYNLGLAYLRLGRYEEALADYEQALeLD-----PDDAEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  224 QFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMdligdnttkERY--AIQYLQKSLEEDPNSGQ 301
Cdd:COG0457    79 LNNLGLALQALGRYEEALEDYDKALELD--PDDAEA--LYNLGLALLEL---------GRYdeAIEAYERALELDPDDAD 145

                         170       180       190
                  ....*....|....*....|....*....|....
gi 755566885  302 SWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASAD 335
Cdd:COG0457   146 ALYNLGIALEKLGRYEEALELLEKLEAAALAALL 179
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 285-391 3.11e-19

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 85.06  E-value: 3.11e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  285 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 364
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                          90       100
                  ....*....|....*....|....*..
gi 755566885  365 HGHAAAWMDLGILYESCNQPQDAIKCY 391
Cdd:COG4235    82 PDNPEALYLLGLAAFQQGDYAEAIAAW 108
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
293-394 3.27e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 85.44  E-value: 3.27e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  293 LEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWM 372
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90       100
                  ....*....|....*....|..
gi 755566885  373 DLGILYESCNQPQDAIKCYLNA 394
Cdd:COG0457    81 NLGLALQALGRYEEALEDYDKA 102
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 285-440 4.34e-17

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 86.59  E-value: 4.34e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  285 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 364
Cdd:COG3914    97 ALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELD 176

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755566885  365 HGHAAAWMDLGILYESCNQPQDAIKCYLNAARsKSCNNTSALTSRIkFLQAQLCNLPQSS-LQNKTKLLPSIEEAWS 440
Cdd:COG3914   177 PDNAEALNNLGNALQDLGRLEEAIAAYRRALE-LDPDNADAHSNLL-FALRQACDWEVYDrFEELLAALARGPSELS 251
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 285-396 2.80e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 74.07  E-value: 2.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  285 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 364
Cdd:COG4783    23 AEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLD 102

                          90       100       110
                  ....*....|....*....|....*....|..
gi 755566885  365 HGHAAAWMDLGILYESCNQPQDAIKCYLNAAR 396
Cdd:COG4783   103 PEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 65-396 3.68e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 77.08  E-value: 3.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   65 LNKAIHFYESLIVKAEGKVESDFfcQLGHFNLLLEDYSKALSSYQryyslqtdywkafqnhfwwwkitrevwKLLLRKFR 144
Cdd:COG2956    24 PDKAIDLLEEALELDPETVEAHL--ALGNLYRRRGEYDRAIRIHQ---------------------------KLLERDPD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  145 NAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNfcrakeihlrlgfmfkmntdyesslkhfqlalidcnvctlsSVEIQ 224
Cdd:COG2956    75 RAEALLELAQDYLKAGLLDRAEELLEKLLELDPD-----------------------------------------DAEAL 113

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  225 FHIAHLYETQRKYHSAKAAYEQLLQIeslpSQVKATVLQQLGwmhhnMDLIGDNTTKEryAIQYLQKSLEEDPNSGQSWY 304
Cdd:COG2956   114 RLLAEIYEQEGDWEKAIEVLERLLKL----GPENAHAYCELA-----ELYLEQGDYDE--AIEALEKALKLDPDCARALL 182

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  305 FLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGhAAAWMDLGILYESCNQP 384
Cdd:COG2956   183 LLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGL 261

                         330
                  ....*....|..
gi 755566885  385 QDAIKCYLNAAR 396
Cdd:COG2956   262 EAALALLERQLR 273
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 314-445 2.25e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 77.73  E-value: 2.25e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  314 GKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLN 393
Cdd:COG3914    92 GRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRR 171

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 755566885  394 AARSKScNNTSALTSRIKFLQaQLCNLPQS--SLQNKTKLLPSIEEAWSLPIPA 445
Cdd:COG3914   172 ALELDP-DNAEALNNLGNALQ-DLGRLEEAiaAYRRALELDPDNADAHSNLLFA 223
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 221-364 7.43e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 67.14  E-value: 7.43e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  221 VEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMDligdnttKERYAIQYLQKSLEEDPNSG 300
Cdd:COG4783     4 AEALYALAQALLLAGDYDEAEALLEKALELD--PDNPEA--FALLGEILLQLG-------DLDEAIVLLHEALELDPDEP 72

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755566885  301 QSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 364
Cdd:COG4783    73 EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 109-391 1.67e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.40  E-value: 1.67e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  109 QRYYSLQTDYWKAFQNHFWWWKITREVWKLLLRKFRNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLR 188
Cdd:COG3914     7 LALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAAL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  189 LgfmFKMNTDYESSLKHFQLAL-IDCNvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGW 267
Cdd:COG3914    87 L---LQALGRYEEALALYRRALaLNPD-----NAEALFNLGNLLLALGRLEEALAALRRALALN--PDFAEA--YLNLGE 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  268 MHHNMDLIGDnttkeryAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKsEASADTWCSIGVLYQQQ 347
Cdd:COG3914   155 ALRRLGRLEE-------AIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALEL-DPDNADAHSNLLFALRQ 226

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 755566885  348 NQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCY 391
Cdd:COG3914   227 ACDWEVYDRFEELLAALARGPSELSPFALLYLPDDDPAELLALA 270
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 301-396 5.06e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.97  E-value: 5.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  301 QSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYES 380
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90
                  ....*....|....*.
gi 755566885  381 CNQPQDAIKCYLNAAR 396
Cdd:COG4783    85 AGDYDEALALLEKALK 100
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
285-364 5.79e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 54.41  E-value: 5.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  285 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAfVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 364
Cdd:COG3063    11 AEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELD 89
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 64-296 6.13e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.59  E-value: 6.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   64 LLNKAIHFYESLIVKAEGKVESdfFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkafqnhfwwwkitrevwklllrkf 143
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEA--LRLLAEIYEQEGDWEKAIEVLERLLKLGPE-------------------------- 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  144 rNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSVE 222
Cdd:COG2956   143 -NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARA---LLLLAELYLEQGDYEEAIAALERALeQD-----PDYLP 213

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755566885  223 IQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQV--KATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEED 296
Cdd:COG2956   214 ALPRLAELYEKLGDPEEALELLRKALELDPSDDLLlaLADLLERKE--------------GLEAALALLERQLRRH 275
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
296-389 7.50e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 57.62  E-value: 7.50e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  296 DPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLG 375
Cdd:COG4785    69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG 148

                          90
                  ....*....|....
gi 755566885  376 ILYESCNQPQDAIK 389
Cdd:COG4785   149 IALYYLGRYELAIA 162
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 285-364 9.13e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.74  E-value: 9.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  285 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 364
Cdd:COG5010    73 SLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 302-416 1.18e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 1.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  302 SWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESC 381
Cdd:COG2956    10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA 89

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 755566885  382 NQPQDAIKCYLNAARSKScNNTSALTSRIKFLQAQ 416
Cdd:COG2956    90 GLLDRAEELLEKLLELDP-DDAEALRLLAEIYEQE 123
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
65-269 1.32e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.32  E-value: 1.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   65 LNKAIHFYESLIVKAEGKVESdfFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkafqnhfwwwkitrevwklllrkfr 144
Cdd:COG0457    24 YEEAIEDYEKALELDPDDAEA--LYNLGLAYLRLGRYEEALADYEQALELDPD--------------------------- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  145 NAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL-IDCNvctlsSVEI 223
Cdd:COG0457    75 DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEA---LYNLGLALLELGRYDEAIEAYERALeLDPD-----DADA 146

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 755566885  224 QFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQVKATVLQQLGWMH 269
Cdd:COG0457   147 LYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAA 192
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 285-397 1.69e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.97  E-value: 1.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  285 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 364
Cdd:COG5010    39 EDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALS 118

                          90       100       110
                  ....*....|....*....|....*....|...
gi 755566885  365 HGHAAAWMDLGILYESCNQPQDAIKCYLNAARS 397
Cdd:COG5010   119 PDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 144-299 3.68e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.66  E-value: 3.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  144 RNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLALIDCNvctlSSVEI 223
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEA---FALLGEILLQLGDLDEAIVLLHEALELDP----DEPEA 74

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755566885  224 QFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQvkATVLQQLGWMHHNMDligdnttKERYAIQYLQKSLEEDPNS 299
Cdd:COG4783    75 RLNLGLALLKAGDYDEALALLEKALKLD--PEH--PEAYLRLARAYRALG-------RPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 220-335 9.02e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.32  E-value: 9.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  220 SVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSqvKATVLQQLGWMHHNMDligdNTTKeryAIQYLQKSLEEDPNS 299
Cdd:COG4235    16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--PD--NADALLDLAEALLAAG----DTEE---AEELLERALALDPDN 84

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 755566885  300 GQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASAD 335
Cdd:COG4235    85 PEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAP 120
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 90-251 1.93e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 51.35  E-value: 1.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   90 QLGHFNLLLEDYSKALSSYQRYYSLQTDywkafqnhfwwwkitrevwklllrkfrNAAFLYGLGLVYFYYNAFQWAIRAF 169
Cdd:COG4783     9 ALAQALLLAGDYDEAEALLEKALELDPD---------------------------NPEAFALLGEILLQLGDLDEAIVLL 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  170 QEVLYVDPNFcraKEIHLRLGFMFKMNTDYESSLKHFQLAL-IDCNvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLL 248
Cdd:COG4783    62 HEALELDPDE---PEARLNLGLALLKAGDYDEALALLEKALkLDPE-----HPEAYLRLARAYRALGRPDEAIAALEKAL 133


                  ...
gi 755566885  249 QIE 251
Cdd:COG4783   134 ELD 136
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
314-396 3.77e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.40  E-value: 3.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  314 GKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQaYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLN 393
Cdd:COG3063     6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                  ...
gi 755566885  394 AAR 396
Cdd:COG3063    85 ALE 87
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 90-210 4.11e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.39  E-value: 4.11e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   90 QLGHFNLLLEDYSKALSSYQRYYSLQTDywkafqnhfwwwkitrevwklllrkfrNAAFLYGLGLVYFYYNAFQWAIRAF 169
Cdd:COG4235    22 LLGRAYLRLGRYDEALAAYEKALRLDPD---------------------------NADALLDLAEALLAAGDTEEAEELL 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 755566885  170 QEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL 210
Cdd:COG4235    75 ERALALDPDNPEA---LYLLGLAAFQQGDYAEAIAAWQKLL 112
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 145-265 1.44e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 1.44e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  145 NAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFcraKEIHLRLGFMFKMNTDYESSLKHFQLAL-IDCNvctlsSVEI 223
Cdd:COG4235    16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN---ADALLDLAEALLAAGDTEEAEELLERALaLDPD-----NPEA 87

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 755566885  224 QFHIAHLYETQRKYHSAKAAYEQLLQIesLPSQVKATVLQQL 265
Cdd:COG4235    88 LYLLGLAAFQQGDYAEAIAAWQKLLAL--LPADAPARLLEAS 127
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 103-253 2.37e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 48.80  E-value: 2.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  103 KALSSYQRYYSLQTDYWKAFQNHFWWWKITREVWKLLLRKFRNAAFLYGLGLVYFYYNAFQW------AIRAFQEVLYVD 176
Cdd:COG5010     5 EGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKlgdfeeSLALLEQALQLD 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755566885  177 PNFcraKEIHLRLGFMFKMNTDYESSLKHFQLALIDCNvctlSSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIESL 253
Cdd:COG5010    85 PNN---PELYYNLALLYSRSGDKDEAKEYYEKALALSP----DNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 144-391 6.13e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 6.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   144 RNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGfMFKM----------------NTDYESSLKHFQ 207
Cdd:TIGR02917  361 DDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAA---RTQLG-ISKLsqgdpseaiadletaaQLDPELGRADLL 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   208 LAL-------IDCNVCTLSSVE--------IQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKATVLQQlgwmhhNM 272
Cdd:TIGR02917  437 LILsylrsgqFDKALAAAKKLEkkqpdnasLHNLLGAIYLGKGDLAKAREAFEKALSIE--PDFFPAAANLA------RI 508

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   273 DLIGDNTTKeryAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMD 352
Cdd:TIGR02917  509 DIQEGNPDD---AIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKK 585

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 755566885   353 ALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCY 391
Cdd:TIGR02917  586 ALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 285-357 3.78e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.21  E-value: 3.78e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755566885  285 AIQYLQKSLEEDPNS---GQSWYFLGRCYSCIGKVQDAFVSYRQSID---KSEASADTWCSIGVLYQQQNQPMDALQAY 357
Cdd:COG1729    12 AIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKrypDSPKAPDALLKLGLSYLELGDYDKARATL 90
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
155-251 4.81e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.24  E-value: 4.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  155 VYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKhFQLAL-IDCNvctlsSVEIQFHIAHLYET 233
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADA---LNNLGLLLLEQGRYDEAIA-LEKALkLDPN-----NAEALLNLAELLLE 71

                          90
                  ....*....|....*...
gi 755566885  234 QRKYHSAKAAYEQLLQIE 251
Cdd:COG3063    72 LGDYDEALAYLERALELD 89
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 65-302 5.71e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 5.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885    65 LNKAIHFYESLIVKAEGKVESdfFCQLGHFNLLLEDYSKALSSYQRYYSLQTDYWKAFQ---NHFWWWKITREVWKLLLR 141
Cdd:TIGR02917  617 LNKAVSSFKKLLALQPDSALA--LLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIglaQLLLAAKRTESAKKIAKS 694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   142 ---KFRNAAFLYGL-GLVYFYYNAFQWAIRAFQEVLYVDP---NFCRAKEIHLRLGFMFKMNTDYESSLKhfqlalIDCN 214
Cdd:TIGR02917  695 lqkQHPKAALGFELeGDLYLRQKDYPAAIQAYRKALKRAPssqNAIKLHRALLASGNTAEAVKTLEAWLK------THPN 768

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   215 vctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQvkATVLQQLGWMHHNMdligdnttKERYAIQYLQKSLE 294
Cdd:TIGR02917  769 -----DAVLRTALAELYLAQKDYDKAIKHYQTVVKKA--PDN--AVVLNNLAWLYLEL--------KDPRALEYAERALK 831


                   ....*...
gi 755566885   295 EDPNSGQS 302
Cdd:TIGR02917  832 LAPNIPAI 839
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 65-210 1.05e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.64  E-value: 1.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885   65 LNKAIHFYESLIvkAEGKVESDFFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkafqnhfwwwkitrevwklllrkfr 144
Cdd:COG4783    20 YDEAEALLEKAL--ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD--------------------------- 70

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755566885  145 NAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFcraKEIHLRLGFMFKMNTDYESSLKHFQLAL 210
Cdd:COG4783    71 EPEARLNLGLALLKAGDYDEALALLEKALKLDPEH---PEAYLRLARAYRALGRPDEAIAALEKAL 133
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 343-416 2.26e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 45.37  E-value: 2.26e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755566885  343 LYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLNAARSKScNNTSALTSRIKFLQAQ 416
Cdd:COG3914    87 LLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNP-DFAEAYLNLGEALRRL 159
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 145-210 2.81e-04

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 43.52  E-value: 2.81e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755566885  145 NAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRakeIHLRLGFMFKMNTDYESSLKHFQLAL 210
Cdd:NF040959  138 NFNLNYRLGLALDGLGQYDKAIEAFQKALELDPNEIK---YHQAIGFMYVQKGDHETAAEHFKKAM 200
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 133-297 2.92e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 2.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  133 REVWKLLLRKFRNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLGfmfkmntDYESSLKHFQLAL-I 211
Cdd:COG5010    11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLG-------DFEESLALLEQALqL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  212 DCNvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvlqqlgwmHHNMDLIGDNTTKERYAIQYLQK 291
Cdd:COG5010    84 DPN-----NPELYYNLALLYSRSGDKDEAKEYYEKALALS--PDNPNA---------YSNLAALLLSLGQDDEAKAALQR 147


                  ....*.
gi 755566885  292 SLEEDP 297
Cdd:COG5010   148 ALGTSP 153
TPR_1 pfam00515
Tetratricopeptide repeat;
146-179 4.33e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 4.33e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 755566885   146 AAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNF 179
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 932-996 6.10e-04

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


Pssm-ID: 214721  Cd Length: 58  Bit Score: 39.16  E-value: 6.10e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755566885    932 QLHELTKLPafvrvvSAGNLLSHVGYTILGMNSVQLC-MKVPGSRIPGHQENNNfcSVNINIGPGD 996
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVGPYLyMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 220-366 6.30e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 43.36  E-value: 6.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  220 SVEIQFHIAHLYETQRKYHSAkaayEQLLQiESLPSQVKATVLQQLGwmhhnmDLIGDNTTKeryAIQYLQKSLEEDPNS 299
Cdd:COG3071   192 DPELAAAYARALIALGDHDEA----ERLLR-EALKRQWDPRLVRLYG------RLQGGDPAK---QLKRAEKWLKKHPND 257

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  300 GQSWYFLGR-CYSC--IGKVQDAFvsyRQSIdKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHG 366
Cdd:COG3071   258 PDLLLALGRlCLRNqlWGKAREYL---EAAL-ALRPSAEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
343-416 1.01e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.38  E-value: 1.01e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755566885  343 LYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKcyLNAARSKSCNNTSALTSRIKFLQAQ 416
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA--LEKALKLDPNNAEALLNLAELLLEL 72
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
285-385 2.97e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.67  E-value: 2.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  285 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 364
Cdd:COG4785    92 AIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELD 171

                          90       100
                  ....*....|....*....|.
gi 755566885  365 HGHAAAWMDLGILYESCNQPQ 385
Cdd:COG4785   172 PNDPERALWLYLAERKLDPEK 192
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 133-210 7.49e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.66  E-value: 7.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  133 REVWKLLLRKFRNAAF----LYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLGFMFKMNTDYESSLKHFQL 208
Cdd:COG1729    13 IAAFKAFLKRYPNSPLapdaLYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELGDYDKARATLEE 92


                  ..
gi 755566885  209 AL 210
Cdd:COG1729    93 LI 94
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 156-249 8.41e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 8.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755566885  156 YFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLGFMFKMNTDYESSLKHFQlALIDCNVCTLSSVEIQFHIAHLYETQR 235
Cdd:COG1729     3 LLKAGDYDEAIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFE-KLLKRYPDSPKAPDALLKLGLSYLELG 81

                          90
                  ....*....|....
gi 755566885  236 KYHSAKAAYEQLLQ 249
Cdd:COG1729    82 DYDKARATLEELIK 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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