NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1039736255|ref|XP_017169874|]
View 

nuclear receptor corepressor 1 isoform X37 [Mus musculus]

Protein Classification

nuclear receptor corepressor 1( domain architecture ID 15502538)

nuclear receptor corepressor 1 (NCOR1) is a transcriptional coregulatory protein which assists nuclear receptors in the down regulation of gene expression

CATH:  1.20.58.1880
Gene Ontology:  GO:0006355|GO:0003700|GO:0003677
PubMed:  8882580|20084085
SCOP:  4000317

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
GPS2_interact super family cl24372
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 150-239 7.55e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


The actual alignment was detected with superfamily member pfam15784:

Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 106.10  E-value: 7.55e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  150 FGSKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 229
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1039736255  230 EQKHRSIVQI 239
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 637-680 6.09e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


:

Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.09e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1039736255  637 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 680
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
MDN1 super family cl34967
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 727-926 3.13e-06

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


The actual alignment was detected with superfamily member COG5271:

Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 52.71  E-value: 3.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  727 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAE------LEATTDPAPcASPSSA 800
Cdd:COG5271    454 DEEEEAEAELDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDAEAEADSDELTAeetsadDGADTDAAA-DPEDSD 532

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  801 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSS-VLDPPAPTKADSVDPEMQvpENTASKGEGDAKERDLES 879
Cdd:COG5271    533 EDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAeTEDATENADADETEESAD--ESEEAEASEDEAAEEEEA 610

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039736255  880 TSEKTEArDEDVVVAEQIERPEPQSDDDSS----ATCSADEGVDGEPERQR 926
Cdd:COG5271    611 DDDEADA-DADGAADEEETEEEAAEDEAAEpetdASEAADEDADAETEAEA 660
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 450-492 1.26e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


:

Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.26e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1039736255  450 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 492
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
GPS2_interact pfam15784
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 150-239 7.55e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 106.10  E-value: 7.55e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  150 FGSKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 229
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1039736255  230 EQKHRSIVQI 239
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 637-680 6.09e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.09e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1039736255  637 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 680
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 637-680 1.32e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 58.36  E-value: 1.32e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1039736255  637 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYK 680
Cdd:cd00167      1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
637-682 2.10e-10

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 58.00  E-value: 2.10e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1039736255   637 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYKRR 682
Cdd:smart00717    3 EWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 727-926 3.13e-06

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 52.71  E-value: 3.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  727 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAE------LEATTDPAPcASPSSA 800
Cdd:COG5271    454 DEEEEAEAELDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDAEAEADSDELTAeetsadDGADTDAAA-DPEDSD 532

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  801 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSS-VLDPPAPTKADSVDPEMQvpENTASKGEGDAKERDLES 879
Cdd:COG5271    533 EDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAeTEDATENADADETEESAD--ESEEAEASEDEAAEEEEA 610

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039736255  880 TSEKTEArDEDVVVAEQIERPEPQSDDDSS----ATCSADEGVDGEPERQR 926
Cdd:COG5271    611 DDDEADA-DADGAADEEETEEEAAEDEAAEpetdASEAADEDADAETEAEA 660
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 761-926 7.34e-05

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 47.67  E-value: 7.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  761 EAAKSSEDSSENAASRGNTEPVAELEATT--DPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEEcGAE 838
Cdd:PRK13108   283 GALRGSEYVVDEALEREPAELAAAAVASAasAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGE-STP 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  839 GSSVLDPPAPTKADSVDPEMQVPENTASKGEGDAKErDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSADEGV 918
Cdd:PRK13108   362 AVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAA-PEEPAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPGDD 440


                   ....*...
gi 1039736255  919 DGEPERQR 926
Cdd:PRK13108   441 PAEPDGIR 448
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 450-492 1.26e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.26e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1039736255  450 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 492
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
448-493 3.88e-04

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 40.28  E-value: 3.88e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1039736255   448 NVWTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTKK 493
Cdd:smart00717    2 GEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 450-489 5.16e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 39.79  E-value: 5.16e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1039736255  450 WTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYY 489
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 693-921 7.42e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.90  E-value: 7.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  693 KQKVSRAVVASRKPREE---RDVSQCESVAStvSAQEDEDIEASNEEENPEDSEG-AENSSDTES---APSPSPVEAAKS 765
Cdd:TIGR00927  613 KEQLSRRPVAKVMALGDlskGDVAEAEHTGE--RTGEEGERPTEAEGENGEESGGeAEQEGETETkgeNESEGEIPAERK 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  766 SEDSSENAASRGNTEPVAELEATTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDP 845
Cdd:TIGR00927  691 GEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGET 770

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  846 PAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSAD---------E 916
Cdd:TIGR00927  771 EAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAEnqgeakqdeK 850


                   ....*
gi 1039736255  917 GVDGE 921
Cdd:TIGR00927  851 GVDGG 855
 
Name Accession Description Interval E-value
GPS2_interact pfam15784
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 150-239 7.55e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 106.10  E-value: 7.55e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  150 FGSKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 229
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1039736255  230 EQKHRSIVQI 239
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 637-680 6.09e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.09e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1039736255  637 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 680
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 637-680 1.32e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 58.36  E-value: 1.32e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1039736255  637 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYK 680
Cdd:cd00167      1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
637-682 2.10e-10

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 58.00  E-value: 2.10e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1039736255   637 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYKRR 682
Cdd:smart00717    3 EWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 727-926 3.13e-06

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 52.71  E-value: 3.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  727 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAE------LEATTDPAPcASPSSA 800
Cdd:COG5271    454 DEEEEAEAELDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDAEAEADSDELTAeetsadDGADTDAAA-DPEDSD 532

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  801 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSS-VLDPPAPTKADSVDPEMQvpENTASKGEGDAKERDLES 879
Cdd:COG5271    533 EDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAeTEDATENADADETEESAD--ESEEAEASEDEAAEEEEA 610

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039736255  880 TSEKTEArDEDVVVAEQIERPEPQSDDDSS----ATCSADEGVDGEPERQR 926
Cdd:COG5271    611 DDDEADA-DADGAADEEETEEEAAEDEAAEpetdASEAADEDADAETEAEA 660
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 702-921 1.59e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 50.40  E-value: 1.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  702 ASRKPREERDVSQCESVASTVSAQEDEDIEAS-----NEEENPEDSEGAENSSDTE------SAPSPSPVEAAKSSEDSS 770
Cdd:COG5271    525 AADPEDSDEDALEDETEGEENAPGSDQDADETdepeaTAEEDEPDEAEAETEDATEnadadeTEESADESEEAEASEDEA 604

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  771 ENAASRGNTEPVAELEATTDPAPCASPSSAVPTTKP------AERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVL- 843
Cdd:COG5271    605 AEEEEADDDEADADADGAADEEETEEEAAEDEAAEPetdaseAADEDADAETEAEASADESEEEAEDESETSSEDAEEDa 684

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  844 -DPPAPTKADSVDPEM---------QVPENTASKGEGDAKERDLESTSEKTEARDE---------DVVVAEQIERPEPQS 904
Cdd:COG5271    685 dAAAAEASDDEEETEEadedaetasEEADAEEADTEADGTAEEAEEAAEEAESADEeaaslpdeaDAEEEAEEAEEAEED 764

                          250
                   ....*....|....*..
gi 1039736255  905 DDDSSATCSADEGVDGE 921
Cdd:COG5271    765 DADGLEEALEEEKADAE 781
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 761-926 7.34e-05

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 47.67  E-value: 7.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  761 EAAKSSEDSSENAASRGNTEPVAELEATT--DPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEEcGAE 838
Cdd:PRK13108   283 GALRGSEYVVDEALEREPAELAAAAVASAasAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGE-STP 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  839 GSSVLDPPAPTKADSVDPEMQVPENTASKGEGDAKErDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSADEGV 918
Cdd:PRK13108   362 AVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAA-PEEPAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPGDD 440


                   ....*...
gi 1039736255  919 DGEPERQR 926
Cdd:PRK13108   441 PAEPDGIR 448
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 716-923 1.21e-04

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 47.70  E-value: 1.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  716 ESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPApcA 795
Cdd:COG5271    561 ATAEEDEPDEAEAETEDATENADADETEESADESEEAEASEDEAAEEEEADDDEADADADGAADEEETEEEAAEDEA--A 638

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  796 SPSSAVPTtkpAERESVEAQVTDSASAETAEPMDVDHEEcgaegssVLDPPAPTKADSVDPEMQVPENTASKGEGDAKER 875
Cdd:COG5271    639 EPETDASE---AADEDADAETEAEASADESEEEAEDESE-------TSSEDAEEDADAAAAEASDDEEETEEADEDAETA 708

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1039736255  876 DLESTSEKTEArDEDVVVAEQIERPEPQSDDDSSATcSADEGVDGEPE 923
Cdd:COG5271    709 SEEADAEEADT-EADGTAEEAEEAAEEAESADEEAA-SLPDEADAEEE 754
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 450-492 1.26e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.26e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1039736255  450 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 492
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 730-886 3.53e-04

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 45.74  E-value: 3.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  730 IEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNT------------EPVAELEATTDPAPCASP 797
Cdd:PRK13108   273 ILAPKGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGPGEpnqpddvaeavkAEVAEVTDEVAAESVVQV 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  798 SSAVPTTKPAERESVEAQVTDSASAET-AEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENTASKGEGDakeRD 876
Cdd:PRK13108   353 ADRDGESTPAVEETSEADIEREQPGDLaGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPDPA---KP 429

                          170
                   ....*....|
gi 1039736255  877 LESTSEKTEA 886
Cdd:PRK13108   430 DELAVAGPGD 439
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
448-493 3.88e-04

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 40.28  E-value: 3.88e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1039736255   448 NVWTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTKK 493
Cdd:smart00717    2 GEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 450-489 5.16e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 39.79  E-value: 5.16e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1039736255  450 WTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYY 489
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
SANT_MTA3_like cd11661
Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family ...
 450-493 9.51e-04

Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family include domains found in mouse metastasis-associated protein 3 (MTA3) proteins and arginine-glutamic dipeptide (RERE) repeats proteins. SANT (SWI3, ADA2, N-CoR and TFIIIB) DNA-binding domains are a diverse set of proteins that share a common 3 alpha-helix bundle. MTA3 has been shown to interact with nucleosome remodeling and deacetylase (NuRD) proteins CHD4 and HDAC1, and the core cohesin complex protein RAD21 in the ovary, and regulate G2/M progression in proliferating granulosa cells. RERE belongs to the atrophin family and has been identified as a nuclear receptor corepressor; altered expression levels of RERE are associated with cancer in humans while mutations of Rere in mice cause failure in closing the anterior neural tube and fusion of the telencephalic and optic vesicles during embryogenesis.


Pssm-ID: 212559 [Multi-domain]  Cd Length: 46  Bit Score: 39.13  E-value: 9.51e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1039736255  450 WTDHEKEIFKDKFIQHPKNFGLI-ASYLERKSVPDCVLYYYLTKK 493
Cdd:cd11661      2 WSESEAKLFEEGLRKYGKDFHDIrQDFLPWKSVGELVEFYYMWKK 46
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 721-923 1.04e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 44.62  E-value: 1.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  721 TVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPAPCASPSSA 800
Cdd:COG5271    266 GTPDTDDEATDDADGLEAAEDDALDAELTAAQAADPESDDDADDSTLAALEGAAEDTEIATADELAAADDEDDDDSAAED 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  801 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENTASKGEGDAKERDLEST 880
Cdd:COG5271    346 AAEEAATAEDSAAEDTQDAEDEAAGEAADESEGADTDAAADEADAAADDSADDEEASADGGTSPTSDTDEEEEEADEDAS 425

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1039736255  881 SEKTEARDEDVVVAEQIErpepqsDDDSSATCSADEGVDGEPE 923
Cdd:COG5271    426 AGETEDESTDVTSAEDDI------ATDEEADSLADEEEEAEAE 462
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 742-942 1.16e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.39  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  742 SEGAENSSDTESAPSPSPVEAAKSSEDSS----------------ENAASRGNTEPVAELEATTDPA-PCASPSSAVPTT 804
Cdd:PHA03307    58 GAAACDRFEPPTGPPPGPGTEAPANESRStptwslstlapasparEGSPTPPGPSSPDPPPPTPPPAsPPPSPAPDLSEM 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  805 KPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENT-ASKGEGDAKERDLESTSek 883
Cdd:PHA03307   138 LRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTpPAAASPRPPRRSSPISA-- 215

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039736255  884 tEARDEDVVVAEQIERPEPQSDDDSSATCSADEGVDGEPERQRvfPMDAKPSLLTPPGS 942
Cdd:PHA03307   216 -SASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPL--PRPAPITLPTRIWE 271
PHA03169 PHA03169
hypothetical protein; Provisional
 690-890 1.93e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 43.04  E-value: 1.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  690 QQHKQKVSRAVVASRKPREERDVS-----QCESVASTVSAQEDEDIEASNEE---ENPEDSEGAENSSDTESAPSPSPVE 761
Cdd:PHA03169    28 GTREQAGRRRGTAARAAKPAPPAPttsgpQVRAVAEQGHRQTESDTETAEESrhgEKEERGQGGPSGSGSESVGSPTPSP 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  762 AAKSSEDSS----ENAASRGNTEPVAELEATTDPAPCASPSSAVPTT---KPAERESVEAQVTDSASAETAEPMDVDHEE 834
Cdd:PHA03169   108 SGSAEELASglspENTSGSSPESPASHSPPPSPPSHPGPHEPAPPEShnpSPNQQPSSFLQPSHEDSPEEPEPPTSEPEP 187

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039736255  835 CGAEGSSVLDP-PAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDED 890
Cdd:PHA03169   188 DSPGPPQSETPtSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREG 244
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 702-874 2.04e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 43.54  E-value: 2.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  702 ASRKPREERDVSQCESVASTVSAQ----EDEDIEASNEEENPEDSEGAENSSDTESAPSPSP-----VEAAKSSEDSSEN 772
Cdd:PRK08691   390 AAKKPQPRPEAETAQTPVQTASAAampsEGKTAGPVSNQENNDVPPWEDAPDEAQTAAGTAQtsaksIQTASEAETPPEN 469

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  773 AASRgNTEPVAELEATTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEgssvlDPPAPTkad 852
Cdd:PRK08691   470 QVSK-NKAADNETDAPLSEVPSENPIQATPNDEAVETETFAHEAPAEPFYGYGFPDNDCPPEDGAE-----IPPPDW--- 540

                          170       180
                   ....*....|....*....|..
gi 1039736255  853 svdpEMQVPENTASKGEGDAKE 874
Cdd:PRK08691   541 ----EHAAPADTAGGGADEEAE 558
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 723-923 2.30e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 43.46  E-value: 2.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  723 SAQEDEDIEASNEEENPED---------SEGAENSSDTEsapspSPVEAAKSSEDSSENAASRGNTEpvaelEATTDPAP 793
Cdd:COG5271    645 SEAADEDADAETEAEASADeseeeaedeSETSSEDAEED-----ADAAAAEASDDEEETEEADEDAE-----TASEEADA 714

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  794 CASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDppAPTKADSVDPEMQVPENTASKGEGDAK 873
Cdd:COG5271    715 EEADTEADGTAEEAEEAAEEAESADEEAASLPDEADAEEEAEEAEEAEEDD--ADGLEEALEEEKADAEEAATDEEAEAA 792

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039736255  874 ERDLESTSEKTEARDEDVVVAEQIE--------RPEPQSDDDSSATCSADEGVDGEPE 923
Cdd:COG5271    793 AEEKEKVADEDQDTDEDALLDEAEAdeeedldgEDEETADEALEDIEAGIAEDDEEDD 850
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 638-685 2.66e-03

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 38.06  E-value: 2.66e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1039736255  638 WTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKnFYFNYKRRHNL 685
Cdd:pfam13921    1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCF-DRWRRKLNPKI 47
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 760-923 3.60e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 42.27  E-value: 3.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  760 VEAAKSSEDSsenAASRGNtEPVAELEATTDPAPCA-----SPSSAVPTTKPAEresvEAQVTDSASAETAEPMDVDHEE 834
Cdd:PRK13108   273 ILAPKGREAP---GALRGS-EYVVDEALEREPAELAaaavaSAASAVGPVGPGE----PNQPDDVAEAVKAEVAEVTDEV 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  835 CGAEGSSVLD-----PPAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSS 909
Cdd:PRK13108   345 AAESVVQVADrdgesTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIP 424

                          170
                   ....*....|....
gi 1039736255  910 ATCSADEGVDGEPE 923
Cdd:PRK13108   425 DPAKPDELAVAGPG 438
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 726-924 3.82e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 42.69  E-value: 3.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  726 EDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPAPCASPSSAVpttK 805
Cdd:COG5271    514 TSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAETEDATENADADETEE---S 590

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  806 PAERESVEAQVTDSASAETAEPMDVDheecgAEGSSVLDppaptKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTE 885
Cdd:COG5271    591 ADESEEAEASEDEAAEEEEADDDEAD-----ADADGAAD-----EEETEEEAAEDEAAEPETDASEAADEDADAETEAEA 660

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1039736255  886 ARDEDVV-VAEQIERPEPQSDDDSSATcSADEGVDGEPER 924
Cdd:COG5271    661 SADESEEeAEDESETSSEDAEEDADAA-AAEASDDEEETE 699
PHA03169 PHA03169
hypothetical protein; Provisional
 680-926 4.92e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 41.88  E-value: 4.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  680 KRRHNLDNLLQQH-KQKVSRAVVASRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPS 758
Cdd:PHA03169    10 RSRHTLRSSCRGHcKRHGGTREQAGRRRGTAARAAKPAPPAPTTSGPQVRAVAEQGHRQTESDTETAEESRHGEKEERGQ 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  759 PVEAAKSSEDSSENAASRGNTEPV----AELEATTDPAPCASPSSAVPTTKPAERESVEaqvtdSASAETAEPMDVDHEE 834
Cdd:PHA03169    90 GGPSGSGSESVGSPTPSPSGSAEElasgLSPENTSGSSPESPASHSPPPSPPSHPGPHE-----PAPPESHNPSPNQQPS 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  835 CGAEGSSVLDPPAPTKADSVDPEmQVPENTASKGEGDAKERDLESTSEKTEARDEdvvvAEQIERPEPQSDDDSSATCSA 914
Cdd:PHA03169   165 SFLQPSHEDSPEEPEPPTSEPEP-DSPGPPQSETPTSSPPPQSPPDEPGEPQSPT----PQQAPSPNTQQAVEHEDEPTE 239

                          250
                   ....*....|..
gi 1039736255  915 DEGVDGEPERQR 926
Cdd:PHA03169   240 PEREGPPFPGHR 251
rne PRK10811
ribonuclease E; Reviewed
 701-867 5.14e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 42.33  E-value: 5.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  701 VASRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTE 780
Cdd:PRK10811   847 VVRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTE 926

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  781 PVAELEATTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQV 860
Cdd:PRK10811   927 QPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQV 1006


                   ....*..
gi 1039736255  861 PENTASK 867
Cdd:PRK10811  1007 PEATVEH 1013
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 693-921 7.42e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.90  E-value: 7.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  693 KQKVSRAVVASRKPREE---RDVSQCESVAStvSAQEDEDIEASNEEENPEDSEG-AENSSDTES---APSPSPVEAAKS 765
Cdd:TIGR00927  613 KEQLSRRPVAKVMALGDlskGDVAEAEHTGE--RTGEEGERPTEAEGENGEESGGeAEQEGETETkgeNESEGEIPAERK 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  766 SEDSSENAASRGNTEPVAELEATTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDP 845
Cdd:TIGR00927  691 GEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGET 770

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  846 PAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSAD---------E 916
Cdd:TIGR00927  771 EAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAEnqgeakqdeK 850


                   ....*
gi 1039736255  917 GVDGE 921
Cdd:TIGR00927  851 GVDGG 855
motB PRK12799
flagellar motor protein MotB; Reviewed
 725-867 9.86e-03

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 40.85  E-value: 9.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039736255  725 QEDEDIEASNEEE---NPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVA-------ELEATTDPAPC 794
Cdd:PRK12799   267 QSQHDIEHENLDNralDIEKATGLKQIDTHGTVPVAAVTPSSAVTQSSAITPSSAAIPSPAVipssvttQSATTTQASAV 346

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039736255  795 ASPSSAVPTTKPAERESVEAQVTDSASAEtAEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENTASK 867
Cdd:PRK12799   347 ALSSAGVLPSDVTLPGTVALPAAEPVNMQ-PQPMSTTETQQSSTGNITSTANGPTTSLPAAPASNIPVSPTSR 418
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH