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Conserved domains on  [gi|1196773644|ref|XP_021099005|]
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nuclear mitotic apparatus protein 1 isoform X2 [Heterocephalus glaber]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-181 4.86e-45

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


:

Pssm-ID: 411795  Cd Length: 148  Bit Score: 160.05  E-value: 4.86e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644    6 TRAAALLSWkspqnhvnqetqifvftlrtpvklpgpskVNSLRVADLVEAVPQLQDCSVFIKIIDGIRGTEEGQQILQQP 85
Cdd:cd22224      2 TKAEALLSW-----------------------------VNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLS 52

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644   86 VPERLDFVCSFLQKNRKRPSSPECLVSMQKVMEG--SELELAKIIMLLLYHSSMSsqNLRDWEQFEYRIQAELAVILKFM 163
Cdd:cd22224     53 VEERLEFISSFLEGDCRFNSSQGTLVSWQKILQGenLELELAKVLLLLLYHSMMN--NNLTLEKLDYKTELELASILRFV 130

                          170
                   ....*....|....*...
gi 1196773644  164 LDHEDGLNLTEDLEIFLQ 181
Cdd:cd22224    131 LDNEDGLYLSEGLDKFLT 148
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1887-1945 3.51e-27

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


:

Pssm-ID: 412093  Cd Length: 56  Bit Score: 105.76  E-value: 3.51e-27
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1196773644 1887 LLSLPGYRPTTRSSTRRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1945
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 582-1358 8.36e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.15  E-value: 8.36e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  582 VEQLSGSLKQKEKQLEEA--ARELDASRRDHAQQLATA-AKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANE 658
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAerYKELKAELRELELALLVLrLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  659 AQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKateREKVAQEKAQLQEQLWSLEE 738
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAEELAELEEKLEELKE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  739 SLKITKGSLEEEKCRAAAA---LEEHQHHISEMEAESRSLAEQHKQERKELEEekakrrgLGVQLQQLAEtHQAETKALR 815
Cdd:TIGR02168  352 ELESLEAELEELEAELEELesrLEELEEQLETLRSKVAQLELQIASLNNEIER-------LEARLERLED-RRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  816 QELAKARTSNNMAE--REVELLVKEVKTWRKRYEDsqqgetqygLQEQLTTLKEEYEKSCQELRETKEKMAgieahselQ 893
Cdd:TIGR02168  424 EELLKKLEEAELKElqAELEELEEELEELQEELER---------LEEALEELREELEEAEQALDAAERELA--------Q 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  894 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKA-------GEQQETASLELLK 966
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRlqavvveNLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  967 EPPKTRDRESEwVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALmesqgqqqeergqQEREVARLTQERGQAEAD 1046
Cdd:TIGR02168  567 QNELGRVTFLP-LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKL-------------RKALSYLLGGVLVVDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1047 LALEKAAKAELEMRL----------QNALNEQQAEFANLQEALSRALSEKEgkdQELSKLCEQEAVQRMELKELLQTVEQ 1116
Cdd:TIGR02168  633 NALELAKKLRPGYRIvtldgdlvrpGGVITGGSAKTNSSILERRREIEELE---EKIEELEEKIAELEKALAELRKELEE 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1117 LKAQLAKKEKEQQQSARGASGENASgmgtQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALE 1196
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKD----LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1197 TLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKE 1276
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1277 GESKELKRLVIAESEKSQKLEERLRLL--QMETASNSARAAE-RSSALREEVQSLREEVEKQRAASENLRQELASQAERA 1353
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945


                   ....*
gi 1196773644 1354 EELGQ 1358
Cdd:TIGR02168  946 SEEYS 950
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1152-1673 4.66e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.17  E-value: 4.66e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1152 KMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELG--------------YSQAASA 1217
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArleqdiarleerrrELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1218 SAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLE 1297
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1298 ERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSAL 1377
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1378 QLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLR---TELMRAQRELGELVPLRQKVAEQERAA 1454
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLigvEAAYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1455 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQE 1528
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1529 VQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQT 1608
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1609 QLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAkkqqNQELQEQLQGLEQLQKENKELRAEAERLG 1673
Cdd:COG1196    720 ELEEEALEEQLEAEREELLEELLEEEELLEEE----ALEELPEPPDLEELERELERLEREIEALG 780
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 244-840 7.67e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.31  E-value: 7.67e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  244 QMRRLKKQ---------LADERNNRDeLELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAAspLEpRELEELRGKN 314
Cdd:COG1196    201 QLEPLERQaekaeryreLKEELKELE-AELLLLKLRELEAELEELEAELEELEAELEELEAELAE--LE-AELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  315 ESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEEngdlsfklrefasnLQQLQGALNELTEEHskatQQWVEKQAHLEKE 394
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIARLEER--------------RRELEERLEELEEEL----AELEEELEELEEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  395 LSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQ 474
Cdd:COG1196    339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  475 KEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLK 554
Cdd:COG1196    419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  555 QQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAareLDASRRDHAQQLATAAKAQETSLRERDAACQQ 634
Cdd:COG1196    499 AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA---LAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  635 LEALEKEKAAKLEILQQQLQAANEAQDSAqnsvtQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQ 714
Cdd:COG1196    576 FLPLDKIRARAALAAALARGAIGAAVDLV-----ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  715 KATEREKVAQEKAQLQEQlwSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRR 794
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRR--ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 1196773644  795 GLGVQLQQLAETHQAETKALRQELAKARTSN---NMAEREVELLVKEVK 840
Cdd:COG1196    729 QLEAEREELLEELLEEEELLEEEALEELPEPpdlEELERELERLEREIE 777
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 1763-2018 2.66e-04

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.32  E-value: 2.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1763 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGPA--PLESSLDSLGEPFLDSGRKTRSA-------------RRR 1827
Cdd:PHA03307   192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENEcplprpapitlptRIW 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1828 TTQIINITMTKKLDVEEPDSANSSfYSTRSAPASQAGLRATSSTQSLARLGSPDDGNSAllslpgyrpTTRSSTRRSQAG 1907
Cdd:PHA03307   271 EASGWNGPSSRPGPASSSSSPRER-SPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS---------TSSSSESSRGAA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1908 VSSGAPPGRNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlglatitdeemktgdpqETLRRASM 1987
Cdd:PHA03307   341 VSPGPSPSRS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARA 392

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1196773644 1988 Q---PGQIAEGAGITTRQQRKRVSSETHQGPGTP 2018
Cdd:PHA03307   393 AvagRARRRDATGRFPAGRPRPSPLDAGAASGAF 426
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-181 4.86e-45

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 160.05  E-value: 4.86e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644    6 TRAAALLSWkspqnhvnqetqifvftlrtpvklpgpskVNSLRVADLVEAVPQLQDCSVFIKIIDGIRGTEEGQQILQQP 85
Cdd:cd22224      2 TKAEALLSW-----------------------------VNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLS 52

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644   86 VPERLDFVCSFLQKNRKRPSSPECLVSMQKVMEG--SELELAKIIMLLLYHSSMSsqNLRDWEQFEYRIQAELAVILKFM 163
Cdd:cd22224     53 VEERLEFISSFLEGDCRFNSSQGTLVSWQKILQGenLELELAKVLLLLLYHSMMN--NNLTLEKLDYKTELELASILRFV 130

                          170
                   ....*....|....*...
gi 1196773644  164 LDHEDGLNLTEDLEIFLQ 181
Cdd:cd22224    131 LDNEDGLYLSEGLDKFLT 148
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1887-1945 3.51e-27

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 105.76  E-value: 3.51e-27
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1196773644 1887 LLSLPGYRPTTRSSTRRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1945
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 582-1358 8.36e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.15  E-value: 8.36e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  582 VEQLSGSLKQKEKQLEEA--ARELDASRRDHAQQLATA-AKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANE 658
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAerYKELKAELRELELALLVLrLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  659 AQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKateREKVAQEKAQLQEQLWSLEE 738
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAEELAELEEKLEELKE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  739 SLKITKGSLEEEKCRAAAA---LEEHQHHISEMEAESRSLAEQHKQERKELEEekakrrgLGVQLQQLAEtHQAETKALR 815
Cdd:TIGR02168  352 ELESLEAELEELEAELEELesrLEELEEQLETLRSKVAQLELQIASLNNEIER-------LEARLERLED-RRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  816 QELAKARTSNNMAE--REVELLVKEVKTWRKRYEDsqqgetqygLQEQLTTLKEEYEKSCQELRETKEKMAgieahselQ 893
Cdd:TIGR02168  424 EELLKKLEEAELKElqAELEELEEELEELQEELER---------LEEALEELREELEEAEQALDAAERELA--------Q 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  894 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKA-------GEQQETASLELLK 966
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRlqavvveNLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  967 EPPKTRDRESEwVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALmesqgqqqeergqQEREVARLTQERGQAEAD 1046
Cdd:TIGR02168  567 QNELGRVTFLP-LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKL-------------RKALSYLLGGVLVVDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1047 LALEKAAKAELEMRL----------QNALNEQQAEFANLQEALSRALSEKEgkdQELSKLCEQEAVQRMELKELLQTVEQ 1116
Cdd:TIGR02168  633 NALELAKKLRPGYRIvtldgdlvrpGGVITGGSAKTNSSILERRREIEELE---EKIEELEEKIAELEKALAELRKELEE 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1117 LKAQLAKKEKEQQQSARGASGENASgmgtQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALE 1196
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKD----LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1197 TLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKE 1276
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1277 GESKELKRLVIAESEKSQKLEERLRLL--QMETASNSARAAE-RSSALREEVQSLREEVEKQRAASENLRQELASQAERA 1353
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945


                   ....*
gi 1196773644 1354 EELGQ 1358
Cdd:TIGR02168  946 SEEYS 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 500-1081 2.96e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.49  E-value: 2.96e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  500 LQSSISNLSQAKEELEQAsQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLR 579
Cdd:COG1196    227 AELLLLKLRELEAELEEL-EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  580 HQVEQLSgSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQEtslrERDAACQQLEALEKEKAAKLEILQQQLQAANEA 659
Cdd:COG1196    306 RLEERRR-ELEERLEELEEELAELEEELEELEEELEELEEELE----EAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  660 QDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQlwslees 739
Cdd:COG1196    381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE------- 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  740 lkitkgsLEEEKCRAAAALEEHQhhisemeaESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELA 819
Cdd:COG1196    454 -------LEEEEEALLELLAELL--------EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  820 KARtsnnmaereVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKE------EYEKSCQELRETKEKMAGIEAHSELQ 893
Cdd:COG1196    519 LRG---------LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEvaaaaiEYLKAAKAGRATFLPLDKIRARAALA 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  894 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRD 973
Cdd:COG1196    590 AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  974 R-ESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKA 1052
Cdd:COG1196    670 LlAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE 749

                          570       580
                   ....*....|....*....|....*....
gi 1196773644 1053 AKAELEMRLQNALNEQQAEFANLQEALSR 1081
Cdd:COG1196    750 EEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1152-1673 4.66e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.17  E-value: 4.66e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1152 KMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELG--------------YSQAASA 1217
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArleqdiarleerrrELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1218 SAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLE 1297
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1298 ERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSAL 1377
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1378 QLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLR---TELMRAQRELGELVPLRQKVAEQERAA 1454
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLigvEAAYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1455 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQE 1528
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1529 VQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQT 1608
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1609 QLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAkkqqNQELQEQLQGLEQLQKENKELRAEAERLG 1673
Cdd:COG1196    720 ELEEEALEEQLEAEREELLEELLEEEELLEEE----ALEELPEPPDLEELERELERLEREIEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 601-1359 6.53e-21

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 100.99  E-value: 6.53e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  601 RELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQRE------- 673
Cdd:PTZ00121  1045 KDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAeeakkka 1124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  674 ----KAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQE-----QLWSLEESLKITK 744
Cdd:PTZ00121  1125 edarKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEvrkaeELRKAEDARKAEA 1204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  745 GSLEEEKCRAaaalEEHQHHISEMEAESRSLAEQHK---QERKELEEEKAKRRGLGVQLQQLAE------THQAETKALR 815
Cdd:PTZ00121  1205 ARKAEEERKA----EEARKAEDAKKAEAVKKAEEAKkdaEEAKKAEEERNNEEIRKFEEARMAHfarrqaAIKAEEARKA 1280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  816 QELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRETKE--KMAGIEAHSELQ 893
Cdd:PTZ00121  1281 DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEaaKAEAEAAADEAE 1360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  894 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRD 973
Cdd:PTZ00121  1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  974 RESEWVEE--QQGQQLCSTQAALRAME--REAEQMGTELEKLRAAlmESQGQQQEERGQQEREVARLTQERGQAEADLAL 1049
Cdd:PTZ00121  1441 EEAKKADEakKKAEEAKKAEEAKKKAEeaKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1050 EKAAKAElemRLQNALNEQQAEFANLQEALSRAlsEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQ 1129
Cdd:PTZ00121  1519 EEAKKAD---EAKKAEEAKKADEAKKAEEKKKA--DELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1130 QSARGASGENASGMgtQSEAVGKMEALRAKVSKLeQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKAREL 1209
Cdd:PTZ00121  1594 IEEVMKLYEEEKKM--KAEEAKKAEEAKIKAEEL-KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1210 GYSQAASASAQRELATLRAKAQDHSKAEEEWKA--QVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVI 1287
Cdd:PTZ00121  1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKaeELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1196773644 1288 AESEKSQKLEErlrLLQMETASNSARAAERSSALREEVqslREEVEKQRAASENLRQELASQAERAEELGQE 1359
Cdd:PTZ00121  1751 KDEEEKKKIAH---LKKEEEKKAEEIRKEKEAVIEEEL---DEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
PTZ00121 PTZ00121
MAEBL; Provisional
 1035-1739 1.73e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 99.83  E-value: 1.73e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1035 RLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQ----EAVQRME---- 1106
Cdd:PTZ00121  1110 KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDakkaEAARKAEevrk 1189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1107 LKELLQTVEQLKAQLAKKEKEQQ--QSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESE 1184
Cdd:PTZ00121  1190 AEELRKAEDARKAEAARKAEEERkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQ 1269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1185 RAFHVERDRALETLQGQLEEKARElgysQAASASAQRELATLRAKAQDHSKAEE-EWKAQVARGQQEAVRKGSLISSLEE 1263
Cdd:PTZ00121  1270 AAIKAEEARKADELKKAEEKKKAD----EAKKAEEKKKADEAKKKAEEAKKADEaKKKAEEAKKKADAAKKKAEEAKKAA 1345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1264 EVSILNRQVLEKEGESKELKrlviAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASEnlr 1343
Cdd:PTZ00121  1346 EAAKAEAEAAADEAEAAEEK----AEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK--- 1418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1344 qelasQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP--AKHLCQQLQAEQVAAEKRHREELEQSKQ 1421
Cdd:PTZ00121  1419 -----KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkkAEEAKKADEAKKKAEEAKKADEAKKKAE 1493

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1422 AAGGLRTELMRAQRELGELVPLRQkvAEQERAAQQLR-AEKASYAEQLsmlKKAHGLLAEENRGLGERANLGRQFLEVEl 1500
Cdd:PTZ00121  1494 EAKKKADEAKKAAEAKKKADEAKK--AEEAKKADEAKkAEEAKKADEA---KKAEEKKKADELKKAEELKKAEEKKKAE- 1567

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1501 dQAREKYIQELAAVRGDAETRLAEMR--QEVQSTTHELEVMTA----KYEGAKVKVlEERQRFQEERQKltaqVEELSKK 1574
Cdd:PTZ00121  1568 -EAKKAEEDKNMALRKAEEAKKAEEAriEEVMKLYEEEKKMKAeeakKAEEAKIKA-EELKKAEEEKKK----VEQLKKK 1641

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1575 LADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQlqg 1654
Cdd:PTZ00121  1642 EAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA--- 1718

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1655 lEQLQKENKELRAEAERLGQELQQAGLKTKEA--EQTCRHLTAQVRSLEAQVAHADQQLRElgkfQVASDALKSREPQAK 1732
Cdd:PTZ00121  1719 -EELKKAEEENKIKAEEAKKEAEEDKKKAEEAkkDEEEKKKIAHLKKEEEKKAEEIRKEKE----AVIEEELDEEDEKRR 1793


                   ....*..
gi 1196773644 1733 PQLDLSI 1739
Cdd:PTZ00121  1794 MEVDKKI 1800
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 244-840 7.67e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.31  E-value: 7.67e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  244 QMRRLKKQ---------LADERNNRDeLELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAAspLEpRELEELRGKN 314
Cdd:COG1196    201 QLEPLERQaekaeryreLKEELKELE-AELLLLKLRELEAELEELEAELEELEAELEELEAELAE--LE-AELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  315 ESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEEngdlsfklrefasnLQQLQGALNELTEEHskatQQWVEKQAHLEKE 394
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIARLEER--------------RRELEERLEELEEEL----AELEEELEELEEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  395 LSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQ 474
Cdd:COG1196    339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  475 KEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLK 554
Cdd:COG1196    419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  555 QQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAareLDASRRDHAQQLATAAKAQETSLRERDAACQQ 634
Cdd:COG1196    499 AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA---LAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  635 LEALEKEKAAKLEILQQQLQAANEAQDSAqnsvtQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQ 714
Cdd:COG1196    576 FLPLDKIRARAALAAALARGAIGAAVDLV-----ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  715 KATEREKVAQEKAQLQEQlwSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRR 794
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRR--ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 1196773644  795 GLGVQLQQLAETHQAETKALRQELAKARTSN---NMAEREVELLVKEVK 840
Cdd:COG1196    729 QLEAEREELLEELLEEEELLEEEALEELPEPpdlEELERELERLEREIE 777
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1035-1743 5.30e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.71  E-value: 5.30e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1035 RLTQERGQAEADLALE--KAAKAELEmRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQ 1112
Cdd:TIGR02168  217 ELKAELRELELALLVLrlEELREELE-ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1113 TVEQLKAQLakkeKEQQQSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERD 1192
Cdd:TIGR02168  296 EISRLEQQK----QILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1193 RALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGslISSLEEEVSILNRQV 1272
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1273 LEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAerssalreevqSLREEVEKQRAASENLRQELASQAER 1352
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD-----------SLERLQENLEGFSEGVKALLKNQSGL 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1353 AEELGQ--ELKAWQEKFfqkEQALSALQLEHTstQALVSELLPAKHLCQQLQAeQVAAEKRHREELEQSK--QAAGGLRT 1428
Cdd:TIGR02168  519 SGILGVlsELISVDEGY---EAAIEAALGGRL--QAVVVENLNAAKKAIAFLK-QNELGRVTFLPLDSIKgtEIQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1429 ELMRAQRELGELVPLRQKVAEQERAAQQLRAEKA---SYAEQLSMLKK----------------AHGLLAeenrGLGERA 1489
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvdDLDNALELAKKlrpgyrivtldgdlvrPGGVIT----GGSAKT 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1490 NLGRQFLEVELDQAREKyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEER---QRFQEERQKLTA 1566
Cdd:TIGR02168  669 NSSILERRREIEELEEK-IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkdlARLEAEVEQLEE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1567 QVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEhyKVQMEKAKTHYDAkkqqnq 1646
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD--ELRAELTLLNEEA------ 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1647 elQEQLQGLEQLQKENKELRAEAERLGQELqqaglktKEAEQTCRHLTAQVRSLEAQVAHADQQLRELGKFQVASDALKS 1726
Cdd:TIGR02168  820 --ANLRERLESLERRIAATERRLEDLEEQI-------EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          730
                   ....*....|....*..
gi 1196773644 1727 REPQAKPQLDLSIDSLD 1743
Cdd:TIGR02168  891 LLRSELEELSEELRELE 907
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 379-1130 6.94e-12

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 71.16  E-value: 6.94e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  379 KATQQWVEKQAHLEKELSTALQDKKcLEEKNEilqgKLSQLEERLAQLPESPRQEKgevlgdvLQLESLKQEAATLATNN 458
Cdd:pfam02463  146 IIAMMKPERRLEIEEEAAGSRLKRK-KKEALK----KLIEETENLAELIIDLEELK-------LQELKLKEQAKKALEYY 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  459 TQLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTT 538
Cdd:pfam02463  214 QLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAK 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  539 LSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRrdhaQQLATAA 618
Cdd:pfam02463  294 EEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELE----KLQEKLE 369

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  619 KAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEA 698
Cdd:pfam02463  370 QLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEE 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  699 QTQVAALEARLKAEQQKAtEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQ 778
Cdd:pfam02463  450 KEELEKQELKLLKDELEL-KKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAH 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  779 HKQERKELEEEKAKRRGLGVQLQQLAETHQAETKA--LRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQY 856
Cdd:pfam02463  529 GRLGDLGVAVENYKVAISTAVIVEVSATADEVEERqkLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQL 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  857 GLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIG-QHQSELAQLHANLARALQQVQEKEnRAQKLADDLSTLQEK 935
Cdd:pfam02463  609 DKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGlRKGVSLEEGLAEKSEVKASLSELT-KELLEIQELQEKAES 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  936 MAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAAL 1015
Cdd:pfam02463  688 ELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKS 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1016 MESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAElEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSK 1095
Cdd:pfam02463  768 ELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEE-ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQ 846

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 1196773644 1096 LCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQ 1130
Cdd:pfam02463  847 KLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 246-744 7.64e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 64.27  E-value: 7.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  246 RRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAaspLEPRELEELRGKNESLTFRLHETL 325
Cdd:TIGR04523  162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNK---SLESQISELKKQNNQLKDNIEKKQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  326 KQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWV----EKQAHLEKELSTALQD 401
Cdd:TIGR04523  239 QEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISdlnnQKEQDWNKELKSELKN 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  402 KkclEEKNEILQGKLSQLEERLAQLPEsprqekgevlgdvlQLESLKQEAATLATNNTQLQARVEmlenEQGQKEAQLLG 481
Cdd:TIGR04523  319 Q---EKKLEEIQNQISQNNKIISQLNE--------------QISQLKKELTNSESENSEKQRELE----EKQNEIEKLKK 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  482 ERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQ---ASQAQGAKLNAQVASLTAELTTLSAT---LQQQDQELAGLKQ 555
Cdd:TIGR04523  378 ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEqikKLQQEKELLEKEIERLKETIIKNNSEikdLTNQDSVKELIIK 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  556 QAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEeaarELDASRRDHAQQLATAAKAQETSLRERdaacQQL 635
Cdd:TIGR04523  458 NLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELK----KLNEEKKELEEKVKDLTKKISSLKEKI----EKL 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  636 EALEKEKAAKLEILQQQLQAANEAQDSaqnsvTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVaalearlkaeQQK 715
Cdd:TIGR04523  530 ESEKKEKESKISDLEDELNKDDFELKK-----ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELI----------DQK 594

                          490       500
                   ....*....|....*....|....*....
gi 1196773644  716 ATEREKVAQEKAQLQEQLWSLEESLKITK 744
Cdd:TIGR04523  595 EKEKKDLIKEIEEKEKKISSLEKELEKAK 623
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 435-680 2.38e-09

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 62.93  E-value: 2.38e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  435 GEVLGDVLQLESLKQEAATLATNNTQLQARVEMLeNEQGQKEAqllgERSHFEEEKQQLASLITNLQSSISNLSQAKeeL 514
Cdd:NF012221  1528 GYILDNVVATSESSQQADAVSKHAKQDDAAQNAL-ADKERAEA----DRQRLEQEKQQQLAAISGSQSQLESTDQNA--L 1600

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  515 EQASQAQGAKLNAQVASLTAELTTLSATL-----QQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSL 589
Cdd:NF012221  1601 ETNGQAQRDAILEESRAVTKELTTLAQGLdaldsQATYAGESGDQWRNPFAGGLLDRVQEQLDDAKKISGKQLADAKQRH 1680

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  590 KQKEKQLEEAARELDA--SRRDHAQQLATAAKAQ---ETSLRERDAACQQLEALEKEKAAKLEILQQQlQAANEAQDSAQ 664
Cdd:NF012221  1681 VDNQQKVKDAVAKSEAgvAQGEQNQANAEQDIDDakaDAEKRKDDALAKQNEAQQAESDANAAANDAQ-SRGEQDASAAE 1759

                          250
                   ....*....|....*.
gi 1196773644  665 NSVTQAQREKAELSQK 680
Cdd:NF012221  1760 NKANQAQADAKGAKQD 1775
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
234-860 1.43e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.08  E-value: 1.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  234 MGDILQTPQFQMRRLKKQLADERNNRDELElelaEHRKLLTEKDAQISMMQQRIDRLAllnEKQAASPLEPRELEELRGK 313
Cdd:PRK03918   167 LGEVIKEIKRRIERLEKFIKRTENIEELIK----EKEKELEEVLREINEISSELPELR---EELEKLEKEVKELEELKEE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  314 NESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREfasnLQQLQGaLNELTEEHSKATQQWVEKQAHLEK 393
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE----LKELKE-KAEEYIKLSEFYEEYLDELREIEK 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  394 ELSTALQDKKCLEEKNEILQGKLSQLEErLAQLPESPRQEKGEVLGDVLQLESLKQeaatLATNNTQLQARVEMLENEQG 473
Cdd:PRK03918   315 RLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHELYEEAKA----KKEELERLKKRLTGLTPEKL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  474 QKEAQLLGER-SHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQ---AQGAKLNAQ-----VASLTAELTTLSATLQ 544
Cdd:PRK03918   390 EKELEELEKAkEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpVCGRELTEEhrkelLEEYTAELKRIEKELK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  545 QQDQELaglkqqaqkkqaqlaqslqqqeqasqglrhqvEQLSGSLKQKEKQLEEaARELDASRRDHAQQLATAAKAQETS 624
Cdd:PRK03918   470 EIEEKE--------------------------------RKLRKELRELEKVLKK-ESELIKLKELAEQLKELEEKLKKYN 516

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  625 LRERDAACQQLEALeKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEaqtqvaA 704
Cdd:PRK03918   517 LEELEKKAEEYEKL-KEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVE------E 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  705 LEARLKAEQ---QKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcraaAALEEHQHHISEMeaESRSLAEQHKQ 781
Cdd:PRK03918   590 LEERLKELEpfyNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETE----KRLEELRKELEEL--EKKYSEEEYEE 663

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  782 ERKELEEEKAKRRGLGVQLQQLaETHQAETKALRQELAKARTSNNMAEREVELLVK---EVKTWRKRYEDSQQGETQYGL 858
Cdd:PRK03918   664 LREEYLELSRELAGLRAELEEL-EKRREEIKKTLEKLKEELEEREKAKKELEKLEKaleRVEELREKVKKYKALLKERAL 742


                   ..
gi 1196773644  859 QE 860
Cdd:PRK03918   743 SK 744
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 271-887 5.74e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.21  E-value: 5.74e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  271 KLLTEKDAQISMMQQRIdrlallnekqaaSPLEPrELEELRGKNESltfRLHETLKQCQDlktekgQMDRKINQLSEENG 350
Cdd:pfam15921  224 KILRELDTEISYLKGRI------------FPVED-QLEALKSESQN---KIELLLQQHQD------RIEQLISEHEVEIT 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  351 DLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEkelSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESP 430
Cdd:pfam15921  282 GLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLE---STVSQLRSELREAKRMYEDKIEELEKQLVLANSEL 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  431 RQEKGEvlgdvlqLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQ-----------------LLGERSHFEEEKQQL 493
Cdd:pfam15921  359 TEARTE-------RDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhLRRELDDRNMEVQRL 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  494 ASLITNLQSSisnlSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQlaqslqqqeq 573
Cdd:pfam15921  432 EALLKAMKSE----CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT---------- 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  574 asqglrhqVEQLSGSLKQKEKQLEEAARELDA--SRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQ 651
Cdd:pfam15921  498 --------VSDLTASLQEKERAIEATNAEITKlrSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQ 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  652 QLQAANEAQDSAQNSVTQAQREKAELSQKV-------EELHALIEAAHQEQCEAQTQVAALE-----------ARLKAEQ 713
Cdd:pfam15921  570 QIENMTQLVGQHGRTAGAMQVEKAQLEKEIndrrlelQEFKILKDKKDAKIRELEARVSDLElekvklvnagsERLRAVK 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  714 QKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcraaaaleehqhhiSEMEAESRSLAEQHKQERKELEEEKAKR 793
Cdd:pfam15921  650 DIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKS--------------EEMETTTNKLKMQLKSAQSELEQTRNTL 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  794 RGLgvqlqQLAETHQAETK-ALRQELAKARTSNNMAEREVELLVKEVKTWRKryEDSQQGETQYGLQEQLTTLKEEYEKS 872
Cdd:pfam15921  716 KSM-----EGSDGHAMKVAmGMQKQITAKRGQIDALQSKIQFLEEAMTNANK--EKHFLKEEKNKLSQELSTVATEKNKM 788

                          650       660
                   ....*....|....*....|..
gi 1196773644  873 CQEL-------RETKEKMAGIE 887
Cdd:pfam15921  789 AGELevlrsqeRRLKEKVANME 810
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1257-1571 3.03e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.90  E-value: 3.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1257 LISSLEEEVSILNRQVLEKeGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQR 1336
Cdd:pfam17380  274 LLHIVQHQKAVSERQQQEK-FEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELER 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1337 AASENLRQELasQAERAEELGQELKAWQEkffqkeqaLSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREEL 1416
Cdd:pfam17380  353 IRQEERKREL--ERIRQEEIAMEISRMRE--------LERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEM 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1417 EQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAaQQLRAEKASYAEQlsmlKKAHGLLAEENRGLGERANLGRQFL 1496
Cdd:pfam17380  423 EQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQ-QQVERLRQQEEER----KRKKLELEKEKRDRKRAEEQRRKIL 497

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1497 EVELDQAREKYIQElaavRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEEL 1571
Cdd:pfam17380  498 EKELEERKQAMIEE----ERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRL 568
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1763-2018 2.66e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.32  E-value: 2.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1763 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGPA--PLESSLDSLGEPFLDSGRKTRSA-------------RRR 1827
Cdd:PHA03307   192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENEcplprpapitlptRIW 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1828 TTQIINITMTKKLDVEEPDSANSSfYSTRSAPASQAGLRATSSTQSLARLGSPDDGNSAllslpgyrpTTRSSTRRSQAG 1907
Cdd:PHA03307   271 EASGWNGPSSRPGPASSSSSPRER-SPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS---------TSSSSESSRGAA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1908 VSSGAPPGRNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlglatitdeemktgdpqETLRRASM 1987
Cdd:PHA03307   341 VSPGPSPSRS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARA 392

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1196773644 1988 Q---PGQIAEGAGITTRQQRKRVSSETHQGPGTP 2018
Cdd:PHA03307   393 AvagRARRRDATGRFPAGRPRPSPLDAGAASGAF 426
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 295-551 2.24e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 42.67  E-value: 2.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  295 EKQAASPLEPRELEELRG--KNESLTFRLHE--TLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQ------ 364
Cdd:NF033928    35 PKDGIPGLEPKDLLDLFQniRNHARSWSNLEpkIKQLANDLANYARNIVVTGNPIIDLINEMPIIKRGDLTEEElselpp 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  365 ------------QLQGALNEL---TEEHSKATQQWVEK----QAHLEKELSTALQDKKCLEEKN------EILQGKLSQL 419
Cdd:NF033928   115 iplssddkeivkELKEILEDLkndIKDYQQKADDVKKElddfENDLREELLPQLKLKKKLYDDNlgsdsiEELREKIDQL 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  420 EERLAQLPESPRQEKGEVLGDVLQL----------ESLKQEAAtlatnntqlQARVEMLENEQGQKEAQLlgershfeEE 489
Cdd:NF033928   195 EKEIEQLNKEYDDYVKLSFTGLAGGpiglaitggiFGSKAEKI---------RKEKNALIQEIDELQEQL--------KK 257

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1196773644  490 KQQLASLITNLQSSISNLSQAKEELEQASQaqgaKLNAQVASLTAELTTLSATLQQQDQELA 551
Cdd:NF033928   258 KNALLGSLERLQTSLDDILTRMEDALPALK----KLKGVWQSLLTDIDSSINALKEIDDADS 315
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 801-1152 5.09e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 42.13  E-value: 5.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  801 QQLAETHQAETKALRQELAKARTSNNMAEREVellvkevkTWR-KRYEDSQQGETQYglQEQLTTLKEEYEKSCQELRET 879
Cdd:NF012221  1452 QDLSNLTAGEVIALSFDFARRAGLSTNNGIEV--------LWNgEVVFASSGDASAW--QQKTLKLTAKAGSNRLEFKGT 1521

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  880 KEK------MAGIEAHSEL-QIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLstlQEKMAATSKEVARLEALVRK 952
Cdd:NF012221  1522 GHNdglgyiLDNVVATSESsQQADAVSKHAKQDDAAQNALADKERAEADRQRLEQEK---QQQLAAISGSQSQLESTDQN 1598

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  953 A----GEQQETASLE-------LLKEPPKTRD--RESEWVEEQQGQQLcSTQAALRAMEREAEQM-------GTELEKLR 1012
Cdd:NF012221  1599 AletnGQAQRDAILEesravtkELTTLAQGLDalDSQATYAGESGDQW-RNPFAGGLLDRVQEQLddakkisGKQLADAK 1677

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1013 AALMESQGQQQEERGQQEREVARLTQERGQAEADLAlekAAKAELEMRLQNALNEQQ-AEFANLQEALSRALSEKEGkDQ 1091
Cdd:NF012221  1678 QRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDID---DAKADAEKRKDDALAKQNeAQQAESDANAAANDAQSRG-EQ 1753

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1196773644 1092 ElSKLCEQEAVQrmelkellqtvEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGK 1152
Cdd:NF012221  1754 D-ASAAENKANQ-----------AQADAKGAKQDESDKPNRQGAAGSGLSGKAYSVEGVAE 1802
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 282-671 8.08e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.36  E-value: 8.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  282 MMQQRIDRLALLNEKQAASPLEpRELEELRGKNESLTFRLHETLKQCQDLK-TEKGQMDRKINQLSEENGDLSFKLREFA 360
Cdd:NF012221  1457 LTAGEVIALSFDFARRAGLSTN-NGIEVLWNGEVVFASSGDASAWQQKTLKlTAKAGSNRLEFKGTGHNDGLGYILDNVV 1535

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  361 --SNLQQLQGALNELTEEhSKATQQwvekqahlekelstALQDKKCLEEKNEIL-QGKLSQLEE---RLAQLpESPRQEK 434
Cdd:NF012221  1536 atSESSQQADAVSKHAKQ-DDAAQN--------------ALADKERAEADRQRLeQEKQQQLAAisgSQSQL-ESTDQNA 1599

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  435 GEVLGDVlQLESLKQEAATLATNNTQLQARVEMLeNEQGQKEAQLlGE--RSHF------------EEEKQQLASLITNL 500
Cdd:NF012221  1600 LETNGQA-QRDAILEESRAVTKELTTLAQGLDAL-DSQATYAGES-GDqwRNPFagglldrvqeqlDDAKKISGKQLADA 1676

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  501 QSSIS-NLSQAKEELEQ--ASQAQGAKLNAQV------ASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQ 571
Cdd:NF012221  1677 KQRHVdNQQKVKDAVAKseAGVAQGEQNQANAeqdiddAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  572 EQASQGlrHQVEQLSGSLKQKEKqleeaarelDASRRDHAQqlATAAKAQETSLRERDAACQQLEALEKEKAAKL--EIL 649
Cdd:NF012221  1757 AAENKA--NQAQADAKGAKQDES---------DKPNRQGAA--GSGLSGKAYSVEGVAEPGSHINPDSPAAADGRfsEGL 1823

                          410       420
                   ....*....|....*....|..
gi 1196773644  650 QQQLQaanEAQDSAQNSVTQAQ 671
Cdd:NF012221  1824 TEQEQ---EALEGATNAVNRLQ 1842
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-181 4.86e-45

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 160.05  E-value: 4.86e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644    6 TRAAALLSWkspqnhvnqetqifvftlrtpvklpgpskVNSLRVADLVEAVPQLQDCSVFIKIIDGIRGTEEGQQILQQP 85
Cdd:cd22224      2 TKAEALLSW-----------------------------VNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLS 52

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644   86 VPERLDFVCSFLQKNRKRPSSPECLVSMQKVMEG--SELELAKIIMLLLYHSSMSsqNLRDWEQFEYRIQAELAVILKFM 163
Cdd:cd22224     53 VEERLEFISSFLEGDCRFNSSQGTLVSWQKILQGenLELELAKVLLLLLYHSMMN--NNLTLEKLDYKTELELASILRFV 130

                          170
                   ....*....|....*...
gi 1196773644  164 LDHEDGLNLTEDLEIFLQ 181
Cdd:cd22224    131 LDNEDGLYLSEGLDKFLT 148
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1887-1945 3.51e-27

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 105.76  E-value: 3.51e-27
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1196773644 1887 LLSLPGYRPTTRSSTRRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1945
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 582-1358 8.36e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.15  E-value: 8.36e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  582 VEQLSGSLKQKEKQLEEA--ARELDASRRDHAQQLATA-AKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANE 658
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAerYKELKAELRELELALLVLrLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  659 AQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKateREKVAQEKAQLQEQLWSLEE 738
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAEELAELEEKLEELKE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  739 SLKITKGSLEEEKCRAAAA---LEEHQHHISEMEAESRSLAEQHKQERKELEEekakrrgLGVQLQQLAEtHQAETKALR 815
Cdd:TIGR02168  352 ELESLEAELEELEAELEELesrLEELEEQLETLRSKVAQLELQIASLNNEIER-------LEARLERLED-RRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  816 QELAKARTSNNMAE--REVELLVKEVKTWRKRYEDsqqgetqygLQEQLTTLKEEYEKSCQELRETKEKMAgieahselQ 893
Cdd:TIGR02168  424 EELLKKLEEAELKElqAELEELEEELEELQEELER---------LEEALEELREELEEAEQALDAAERELA--------Q 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  894 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKA-------GEQQETASLELLK 966
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRlqavvveNLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  967 EPPKTRDRESEwVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALmesqgqqqeergqQEREVARLTQERGQAEAD 1046
Cdd:TIGR02168  567 QNELGRVTFLP-LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKL-------------RKALSYLLGGVLVVDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1047 LALEKAAKAELEMRL----------QNALNEQQAEFANLQEALSRALSEKEgkdQELSKLCEQEAVQRMELKELLQTVEQ 1116
Cdd:TIGR02168  633 NALELAKKLRPGYRIvtldgdlvrpGGVITGGSAKTNSSILERRREIEELE---EKIEELEEKIAELEKALAELRKELEE 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1117 LKAQLAKKEKEQQQSARGASGENASgmgtQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALE 1196
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKD----LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1197 TLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKE 1276
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1277 GESKELKRLVIAESEKSQKLEERLRLL--QMETASNSARAAE-RSSALREEVQSLREEVEKQRAASENLRQELASQAERA 1353
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945


                   ....*
gi 1196773644 1354 EELGQ 1358
Cdd:TIGR02168  946 SEEYS 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 500-1081 2.96e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.49  E-value: 2.96e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  500 LQSSISNLSQAKEELEQAsQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLR 579
Cdd:COG1196    227 AELLLLKLRELEAELEEL-EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  580 HQVEQLSgSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQEtslrERDAACQQLEALEKEKAAKLEILQQQLQAANEA 659
Cdd:COG1196    306 RLEERRR-ELEERLEELEEELAELEEELEELEEELEELEEELE----EAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  660 QDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQlwslees 739
Cdd:COG1196    381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE------- 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  740 lkitkgsLEEEKCRAAAALEEHQhhisemeaESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELA 819
Cdd:COG1196    454 -------LEEEEEALLELLAELL--------EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  820 KARtsnnmaereVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKE------EYEKSCQELRETKEKMAGIEAHSELQ 893
Cdd:COG1196    519 LRG---------LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEvaaaaiEYLKAAKAGRATFLPLDKIRARAALA 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  894 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRD 973
Cdd:COG1196    590 AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  974 R-ESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKA 1052
Cdd:COG1196    670 LlAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE 749

                          570       580
                   ....*....|....*....|....*....
gi 1196773644 1053 AKAELEMRLQNALNEQQAEFANLQEALSR 1081
Cdd:COG1196    750 EEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 238-964 2.03e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.91  E-value: 2.03e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  238 LQTPQFQMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRL-ALLNEKQAASPLEPRELEELRGKNES 316
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALaNEISRLEQQKQILRERLANLERQLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  317 LTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEH---SKATQQWVEKQAHLEK 393
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetlRSKVAQLELQIASLNN 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  394 ELSTALQDKKCLEEKNEILQgklSQLEERLAQLPESPRQEKGEvlgdvlQLESLKQEAATLATNNTQLQARVEMLENEQG 473
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQA------ELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  474 QKEAQLLGERSHFEEEKQQLASLiTNLQSSISNLSQAKEELEQAsQAQGAKLNAQVASL--------TAELTTLSATLQQ 545
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKN-QSGLSGILGVLSELisvdegyeAAIEAALGGRLQA 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  546 ---QDQELAGLKQQAQKKQAQLAQS----LQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAa 618
Cdd:TIGR02168  550 vvvENLNAAKKAIAFLKQNELGRVTflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVV- 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  619 kaqeTSLRERDAACQQLEALEKEKAAKLEILQQQlQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEA 698
Cdd:TIGR02168  629 ----DDLDNALELAKKLRPGYRIVTLDGDLVRPG-GVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  699 QTQVAALEarlkaeqqkaTEREKVAQEKAQLQEQLWSLEESLKItkgsLEEEKCRAAAALEEHQHHISEMEAESRSLAEQ 778
Cdd:TIGR02168  704 RKELEELE----------EELEQLRKELEELSRQISALRKDLAR----LEAEVEQLEERIAQLSKELTELEAEIEELEER 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  779 HKQERKELEEEKAKRrglgVQLQQLAETHQAETKALRQELAKARtsnnmaerevellvKEVKTWRKRYEDSQQGetqygl 858
Cdd:TIGR02168  770 LEEAEEELAEAEAEI----EELEAQIEQLKEELKALREALDELR--------------AELTLLNEEAANLRER------ 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  859 QEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAA 938
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          730       740
                   ....*....|....*....|....*.
gi 1196773644  939 TSKEVARLEALVRKAGEQQETASLEL 964
Cdd:TIGR02168  906 LESKRSELRRELEELREKLAQLELRL 931
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 331-1110 9.08e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 103.60  E-value: 9.08e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  331 LKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATqqwvEKQAHLEKELSTALQDKKCLEEKNE 410
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELE----EEIEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  411 ILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGERSHFEEEK 490
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  491 QQLASLITNLQSSISNLSQAKEELEQasqaqgakLNAQVASLTAELTTLSATLQQQD-QELAGLKQQAQKKQAQLAQSLQ 569
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLER--------LEDRRERLQQEIEELLKKLEEAElKELQAELEELEEELEELQEELE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  570 QQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRR------DHAQQLATAAKAQETSLRERDAACQQLEALEKEKA 643
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqenleGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEA 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  644 AKLEILQQQLQAA----NEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARL---KAEQQKA 716
Cdd:TIGR02168  538 AIEAALGGRLQAVvvenLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLvkfDPKLRKA 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  717 TE----REKVAQEKAQLQEQLWSLEESLKITkgSLEEEKCRAAAAleehqhhISEMEAESRSLAEQHKQERKELEEEKAK 792
Cdd:TIGR02168  618 LSyllgGVLVVDDLDNALELAKKLRPGYRIV--TLDGDLVRPGGV-------ITGGSAKTNSSILERRREIEELEEKIEE 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  793 RRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYED-----SQQGETQYGLQEQLTTLKE 867
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQleeriAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  868 EYEKSCQELRETKEKMAGIEAhselQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLE 947
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEA----QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLE 844

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  948 ALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQqgQQLCSTQAALRAMEREAEQMGTELEKLRAALMEsqgqqqeerg 1027
Cdd:TIGR02168  845 EQIEELSEDIESLAAEIEELEELIEELESELEALL--NERASLEEALALLRSELEELSEELRELESKRSE---------- 912

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1028 qqerevarLTQERGQAEADLALEKAAKAELEMRLQNalneQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQ-RME 1106
Cdd:TIGR02168  913 --------LRRELEELREKLAQLELRLEGLEVRIDN----LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRlENK 980


                   ....
gi 1196773644 1107 LKEL 1110
Cdd:TIGR02168  981 IKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 865-1673 4.16e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 101.29  E-value: 4.16e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  865 LKEEYEKSCQELRETKEKMAGIE-AHSELQigqHQSELAQLHANLARALQQVQEKENRAQK--LADDLSTLQEKMAATSK 941
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEdILNELE---RQLKSLERQAEKAERYKELKAELRELELalLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  942 EVARLEALVRKAGEQQETASLELLKeppkTRDRESEWVEEQQGQQ--LCSTQAALRAMEREAEQmgteleklraaLMESQ 1019
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEE----LRLEVSELEEEIEELQkeLYALANEISRLEQQKQI-----------LRERL 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1020 GQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQnALNEQQAEFANLQEALSRALSEKEGKDQELSK---- 1095
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE-SLEAELEELEAELEELESRLEELEEQLETLRSkvaq 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1096 LCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKM--------EALRAKVSKLEQQC 1167
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEleelqeelERLEEALEELREEL 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1168 QQQQEEADSLARSLESERAfhveRDRALETLQGQLEEKARELgysqAASASAQRELATLRAKAQDHSKAEEEWKA----- 1242
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQA----RLDSLERLQENLEGFSEGV----KALLKNQSGLSGILGVLSELISVDEGYEAaieaa 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1243 -------------QVARGQQEAVRKGSLISSLEEEVSILNRQVLE---------KEGESKELKRLVIAESEKSQKLEERL 1300
Cdd:TIGR02168  543 lggrlqavvvenlNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQgndreilknIEGFLGVAKDLVKFDPKLRKALSYLL 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1301 RLLQMetASNSARAAERSSALREEVQSLREEVE--------------------KQRAASENLRQELASQAERAEELGQEL 1360
Cdd:TIGR02168  623 GGVLV--VDDLDNALELAKKLRPGYRIVTLDGDlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELEKAL 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1361 KAWQEKFFQKEQALSALQLEHTSTQALVSELlpaKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGEL 1440
Cdd:TIGR02168  701 AELRKELEELEEELEQLRKELEELSRQISAL---RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1441 VPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEveldqAREKYIQELAAVRGDAET 1520
Cdd:TIGR02168  778 AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA-----ATERRLEDLEEQIEELSE 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1521 RLAEMRQEVQSTTHELEVMTAKYEGAkvkvLEERQRFQEERQKLTAQVEELSKKLADYDqaskvqqQKLKAFQAQGGESQ 1600
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEAL----LNERASLEEALALLRSELEELSEELRELE-------SKRSELRRELEELR 921

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1196773644 1601 QEAQRLQTQLNELQVQLSQ-KEQAAEHYKVQMEKAKTHYDAKKQQnqelqeqlqgLEQLQKENKELRAEAERLG 1673
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNlQERLSEEYSLTLEEAEALENKIEDD----------EEEARRRLKRLENKIKELG 985
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1152-1673 4.66e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.17  E-value: 4.66e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1152 KMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELG--------------YSQAASA 1217
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArleqdiarleerrrELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1218 SAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLE 1297
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1298 ERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSAL 1377
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1378 QLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLR---TELMRAQRELGELVPLRQKVAEQERAA 1454
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLigvEAAYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1455 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQE 1528
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1529 VQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQT 1608
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1609 QLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAkkqqNQELQEQLQGLEQLQKENKELRAEAERLG 1673
Cdd:COG1196    720 ELEEEALEEQLEAEREELLEELLEEEELLEEE----ALEELPEPPDLEELERELERLEREIEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 601-1359 6.53e-21

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 100.99  E-value: 6.53e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  601 RELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQRE------- 673
Cdd:PTZ00121  1045 KDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAeeakkka 1124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  674 ----KAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQE-----QLWSLEESLKITK 744
Cdd:PTZ00121  1125 edarKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEvrkaeELRKAEDARKAEA 1204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  745 GSLEEEKCRAaaalEEHQHHISEMEAESRSLAEQHK---QERKELEEEKAKRRGLGVQLQQLAE------THQAETKALR 815
Cdd:PTZ00121  1205 ARKAEEERKA----EEARKAEDAKKAEAVKKAEEAKkdaEEAKKAEEERNNEEIRKFEEARMAHfarrqaAIKAEEARKA 1280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  816 QELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRETKE--KMAGIEAHSELQ 893
Cdd:PTZ00121  1281 DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEaaKAEAEAAADEAE 1360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  894 IGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRD 973
Cdd:PTZ00121  1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  974 RESEWVEE--QQGQQLCSTQAALRAME--REAEQMGTELEKLRAAlmESQGQQQEERGQQEREVARLTQERGQAEADLAL 1049
Cdd:PTZ00121  1441 EEAKKADEakKKAEEAKKAEEAKKKAEeaKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1050 EKAAKAElemRLQNALNEQQAEFANLQEALSRAlsEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQ 1129
Cdd:PTZ00121  1519 EEAKKAD---EAKKAEEAKKADEAKKAEEKKKA--DELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1130 QSARGASGENASGMgtQSEAVGKMEALRAKVSKLeQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKAREL 1209
Cdd:PTZ00121  1594 IEEVMKLYEEEKKM--KAEEAKKAEEAKIKAEEL-KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1210 GYSQAASASAQRELATLRAKAQDHSKAEEEWKA--QVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVI 1287
Cdd:PTZ00121  1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKaeELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1196773644 1288 AESEKSQKLEErlrLLQMETASNSARAAERSSALREEVqslREEVEKQRAASENLRQELASQAERAEELGQE 1359
Cdd:PTZ00121  1751 KDEEEKKKIAH---LKKEEEKKAEEIRKEKEAVIEEEL---DEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 774-1571 1.13e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 1.13e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  774 SLAEQHKQERKELEEekAKRRGLGVQLQQLA---ETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQ 850
Cdd:TIGR02168  210 EKAERYKELKAELRE--LELALLVLRLEELReelEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  851 QG-ETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDL 929
Cdd:TIGR02168  288 KElYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  930 STLQEKMAATSKEVARLEALVRKAGEQQETASLELLK-EPPKTR--DRESEWVEEQQGQQLCSTQAALRAMEREAEQMGT 1006
Cdd:TIGR02168  368 EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERlEARLERleDRRERLQQEIEELLKKLEEAELKELQAELEELEE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1007 ELEKLRAALmesqGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEAlsralSEK 1086
Cdd:TIGR02168  448 ELEELQEEL----ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ-----SGL 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1087 EGKDQELSKLCEQEAVQRMELKELLQTVEQlkaQLAKKEKEQQQSARGASGENASGmgtqseAVGKMEALRAKVSKLEQQ 1166
Cdd:TIGR02168  519 SGILGVLSELISVDEGYEAAIEAALGGRLQ---AVVVENLNAAKKAIAFLKQNELG------RVTFLPLDSIKGTEIQGN 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1167 CQQQQEEADSLARSLESERAFHVERDRALETLQGQL---------EEKARELGYSQA---------------ASASAQRE 1222
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvddldnaLELAKKLRPGYRivtldgdlvrpggviTGGSAKTN 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1223 LATL--RAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERL 1300
Cdd:TIGR02168  670 SSILerRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1301 RLLQmetasnsaraaerssalrEEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLE 1380
Cdd:TIGR02168  750 AQLS------------------KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1381 HTSTQALVSELLPAkhlCQQLQAEQVAAEKRHREELEQSKQAAGglrtELMRAQRELGElvpLRQKVAEQERAAQQLRAE 1460
Cdd:TIGR02168  812 LTLLNEEAANLRER---LESLERRIAATERRLEDLEEQIEELSE----DIESLAAEIEE---LEELIEELESELEALLNE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1461 KASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTtheLEVMT 1540
Cdd:TIGR02168  882 RASLEEALALLRSELEELSEELRELESKRSELRRELE-ELREKLAQLELRLEGLEVRIDNLQERLSEEYSLT---LEEAE 957

                          810       820       830
                   ....*....|....*....|....*....|.
gi 1196773644 1541 AKYEgakvKVLEERQRFQEERQKLTAQVEEL 1571
Cdd:TIGR02168  958 ALEN----KIEDDEEEARRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 1035-1739 1.73e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 99.83  E-value: 1.73e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1035 RLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQ----EAVQRME---- 1106
Cdd:PTZ00121  1110 KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDakkaEAARKAEevrk 1189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1107 LKELLQTVEQLKAQLAKKEKEQQ--QSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESE 1184
Cdd:PTZ00121  1190 AEELRKAEDARKAEAARKAEEERkaEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQ 1269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1185 RAFHVERDRALETLQGQLEEKARElgysQAASASAQRELATLRAKAQDHSKAEE-EWKAQVARGQQEAVRKGSLISSLEE 1263
Cdd:PTZ00121  1270 AAIKAEEARKADELKKAEEKKKAD----EAKKAEEKKKADEAKKKAEEAKKADEaKKKAEEAKKKADAAKKKAEEAKKAA 1345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1264 EVSILNRQVLEKEGESKELKrlviAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASEnlr 1343
Cdd:PTZ00121  1346 EAAKAEAEAAADEAEAAEEK----AEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK--- 1418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1344 qelasQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP--AKHLCQQLQAEQVAAEKRHREELEQSKQ 1421
Cdd:PTZ00121  1419 -----KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKkkAEEAKKADEAKKKAEEAKKADEAKKKAE 1493

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1422 AAGGLRTELMRAQRELGELVPLRQkvAEQERAAQQLR-AEKASYAEQLsmlKKAHGLLAEENRGLGERANLGRQFLEVEl 1500
Cdd:PTZ00121  1494 EAKKKADEAKKAAEAKKKADEAKK--AEEAKKADEAKkAEEAKKADEA---KKAEEKKKADELKKAEELKKAEEKKKAE- 1567

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1501 dQAREKYIQELAAVRGDAETRLAEMR--QEVQSTTHELEVMTA----KYEGAKVKVlEERQRFQEERQKltaqVEELSKK 1574
Cdd:PTZ00121  1568 -EAKKAEEDKNMALRKAEEAKKAEEAriEEVMKLYEEEKKMKAeeakKAEEAKIKA-EELKKAEEEKKK----VEQLKKK 1641

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1575 LADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQlqg 1654
Cdd:PTZ00121  1642 EAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA--- 1718

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1655 lEQLQKENKELRAEAERLGQELQQAGLKTKEA--EQTCRHLTAQVRSLEAQVAHADQQLRElgkfQVASDALKSREPQAK 1732
Cdd:PTZ00121  1719 -EELKKAEEENKIKAEEAKKEAEEDKKKAEEAkkDEEEKKKIAHLKKEEEKKAEEIRKEKE----AVIEEELDEEDEKRR 1793


                   ....*..
gi 1196773644 1733 PQLDLSI 1739
Cdd:PTZ00121  1794 MEVDKKI 1800
PTZ00121 PTZ00121
MAEBL; Provisional
 591-1257 7.18e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 97.90  E-value: 7.18e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  591 QKEKQLEEAARELDASRRDHAQQLATAAKAQEtsLRERDAACQQLEALEKEKAAKLEilqqQLQAANEAQDSAQNSVTQA 670
Cdd:PTZ00121  1161 EDARKAEEARKAEDAKKAEAARKAEEVRKAEE--LRKAEDARKAEAARKAEEERKAE----EARKAEDAKKAEAVKKAEE 1234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  671 QREKAELSQKVEELHALIEAAHQEQCEaQTQVAALEARLKAEQQKATEREKVAQEKAQlQEQLWSLEESLKITKGSLEEE 750
Cdd:PTZ00121  1235 AKKDAEEAKKAEEERNNEEIRKFEEAR-MAHFARRQAAIKAEEARKADELKKAEEKKK-ADEAKKAEEKKKADEAKKKAE 1312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  751 KCRAAaalEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAE- 829
Cdd:PTZ00121  1313 EAKKA---DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEe 1389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  830 -REVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQiGQHQSELAQLHANL 908
Cdd:PTZ00121  1390 kKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAE-EAKKAEEAKKKAEE 1468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  909 ARALQQVQEKENRAQKlADDLSTLQEKMAATSKEvarlealVRKAGEQQETASlELLKEPPKTRDRESEWVEEQQgqqlc 988
Cdd:PTZ00121  1469 AKKADEAKKKAEEAKK-ADEAKKKAEEAKKKADE-------AKKAAEAKKKAD-EAKKAEEAKKADEAKKAEEAK----- 1534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  989 STQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEaDLALEKAAKAELEMRLQNALNEQ 1068
Cdd:PTZ00121  1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE-EARIEEVMKLYEEEKKMKAEEAK 1613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1069 QAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMgTQSE 1148
Cdd:PTZ00121  1614 KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEK-KAAE 1692

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1149 AVGKMEALRAKVSKLEQQCQQQQEEADSLARSLEserafhvERDRALETLQGQLEEKARelgysQAASASAQRElatlRA 1228
Cdd:PTZ00121  1693 ALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEE-------ENKIKAEEAKKEAEEDKK-----KAEEAKKDEE----EK 1756

                          650       660
                   ....*....|....*....|....*....
gi 1196773644 1229 KAQDHSKAEEEWKAQVARGQQEAVRKGSL 1257
Cdd:PTZ00121  1757 KKIAHLKKEEEKKAEEIRKEKEAVIEEEL 1785
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 244-840 7.67e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 97.31  E-value: 7.67e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  244 QMRRLKKQ---------LADERNNRDeLELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAAspLEpRELEELRGKN 314
Cdd:COG1196    201 QLEPLERQaekaeryreLKEELKELE-AELLLLKLRELEAELEELEAELEELEAELEELEAELAE--LE-AELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  315 ESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEEngdlsfklrefasnLQQLQGALNELTEEHskatQQWVEKQAHLEKE 394
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIARLEER--------------RRELEERLEELEEEL----AELEEELEELEEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  395 LSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQ 474
Cdd:COG1196    339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  475 KEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLK 554
Cdd:COG1196    419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  555 QQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAareLDASRRDHAQQLATAAKAQETSLRERDAACQQ 634
Cdd:COG1196    499 AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA---LAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  635 LEALEKEKAAKLEILQQQLQAANEAQDSAqnsvtQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQ 714
Cdd:COG1196    576 FLPLDKIRARAALAAALARGAIGAAVDLV-----ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  715 KATEREKVAQEKAQLQEQlwSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRR 794
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRR--ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 1196773644  795 GLGVQLQQLAETHQAETKALRQELAKARTSN---NMAEREVELLVKEVK 840
Cdd:COG1196    729 QLEAEREELLEELLEEEELLEEEALEELPEPpdlEELERELERLEREIE 777
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 796-1378 1.09e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.54  E-value: 1.09e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  796 LGVQLQQLAEthQAETKALRQELAKARTsnnmaEREVELLVKEVKTwrkryedsqqgetqygLQEQLTTLKEEYEKSCQE 875
Cdd:COG1196    198 LERQLEPLER--QAEKAERYRELKEELK-----ELEAELLLLKLRE----------------LEAELEELEAELEELEAE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  876 LRETKEKMAGIEAHSE---LQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRK 952
Cdd:COG1196    255 LEELEAELAELEAELEelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  953 AGEQQETASLELLKEppKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEqmgtELEKLRAALMESQGQQQEERGQQERE 1032
Cdd:COG1196    335 LEEELEELEEELEEA--EEELEEAEAELAEAEEALLEAEAELAEAEEELE----ELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1033 VARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQ 1112
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1113 TVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKM------------EALRAKVSKLEQQCQQQQEEADSLARS 1180
Cdd:COG1196    489 AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLigveaayeaaleAALAAALQNIVVEDDEVAAAAIEYLKA 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1181 LESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISS 1260
Cdd:COG1196    569 AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1261 LEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASE 1340
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1196773644 1341 NLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQ 1378
Cdd:COG1196    729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 487-1250 1.05e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.58  E-value: 1.05e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  487 EEEKQQLASLITNLQSSISNLSQAKEELEQASQaQGAKLNAQVASLTAELTTLSATLQQQDQELAglkqqaqkkqaQLAQ 566
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEE-ELEELTAELQELEEKLEELRLEVSELEEEIE-----------ELQK 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  567 SLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELD--ASRRDHAQQLATAAKAQETSLRERdaaCQQLEALEKEKAA 644
Cdd:TIGR02168  289 ELYALANEISRLEQQKQILRERLANLERQLEELEAQLEelESKLDELAEELAELEEKLEELKEE---LESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  645 KLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATER--EKV 722
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAelEEL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  723 AQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAeSRSLAEQHKQERKELEEEKAKRRGLGVQLQQ 802
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  803 LAETHQAETK-------ALRQELAKARTSN-NMAEREVELLVKEVKTWRKRYE-DSQQGETQYGLQEQLTTLKEEYEKSC 873
Cdd:TIGR02168  525 LSELISVDEGyeaaieaALGGRLQAVVVENlNAAKKAIAFLKQNELGRVTFLPlDSIKGTEIQGNDREILKNIEGFLGVA 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  874 QELRETKEK----MAGIEAHS----ELQIGQHQSELAQLHANL------------------ARALQQVQEKENRAQKLAD 927
Cdd:TIGR02168  605 KDLVKFDPKlrkaLSYLLGGVlvvdDLDNALELAKKLRPGYRIvtldgdlvrpggvitggsAKTNSSILERRREIEELEE 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  928 DLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMER-EAEQMGT 1006
Cdd:TIGR02168  685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELtELEAEIE 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1007 ELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLAlekaakaelemRLQNALNEQQAEFANLQEALSRALSEK 1086
Cdd:TIGR02168  765 ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD-----------ELRAELTLLNEEAANLRERLESLERRI 833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1087 EGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKE-QQQSARGASGENAsgmgtqseavgkMEALRAKVSKLEQ 1165
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESElEALLNERASLEEA------------LALLRSELEELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1166 QCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKArelgysQAASASAQRELATLRAKAQDHSKAEEEWKAQVA 1245
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ------ERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975


                   ....*
gi 1196773644 1246 RGQQE 1250
Cdd:TIGR02168  976 RLENK 980
PTZ00121 PTZ00121
MAEBL; Provisional
 590-1289 8.99e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 90.97  E-value: 8.99e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  590 KQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRErdaacqqlEALEKEKAAKLEILQQQLQAAN-EAQDSAQNSVT 668
Cdd:PTZ00121  1118 EEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVE--------IARKAEDARKAEEARKAEDAKKaEAARKAEEVRK 1189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  669 QAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATERE-KVAQEKAqlqeqlwSLEESLKITKGSL 747
Cdd:PTZ00121  1190 AEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEaKKAEEER-------NNEEIRKFEEARM 1262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  748 EEEKCRAAAALEEHQHHISEM-EAESRSLAEQHK--QERKELEE--EKAKRRGLGVQLQQLAETHQAETKALRQELAKAR 822
Cdd:PTZ00121  1263 AHFARRQAAIKAEEARKADELkKAEEKKKADEAKkaEEKKKADEakKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAK 1342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  823 TSNNMAEREVELLVKEVKTWRKRYE-DSQQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSEL 901
Cdd:PTZ00121  1343 KAAEAAKAEAEAAADEAEAAEEKAEaAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADE 1422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  902 AQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAA-----TSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRES 976
Cdd:PTZ00121  1423 AKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAeeakkKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  977 EWVEEQQGQqlcsTQAALRAME-REAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEAdlalEKAAKA 1055
Cdd:PTZ00121  1503 KKAAEAKKK----ADEAKKAEEaKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEE----AKKAEE 1574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1056 ELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKlcEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGA 1135
Cdd:PTZ00121  1575 DKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK--AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL 1652

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1136 SGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESER-AFHVERDRALETLQGQLEEKARELGYSQA 1214
Cdd:PTZ00121  1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKkAEELKKKEAEEKKKAEELKKAEEENKIKA 1732

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1215 asASAQRELATLRAKAQDHSKAEEEwKAQVARGQQEAVRKGslissleEEVSILNRQVLEKEGESKELKRLVIAE 1289
Cdd:PTZ00121  1733 --EEAKKEAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKA-------EEIRKEKEAVIEEELDEEDEKRRMEVD 1797
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 355-1131 9.07e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 9.07e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  355 KLREFASNLQQLQGALNELT------EEHSKATQQWVEKQAHL-EKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLP 427
Cdd:TIGR02168  180 KLERTRENLDRLEDILNELErqlkslERQAEKAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  428 ESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENE---QGQKEAQLLGERSHFEEEKQQLASLITNLQSSI 504
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQkqiLRERLANLERQLEELEAQLEELESKLDELAEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  505 SNLSQAKEELEQASQAQGAKLNAQVASLtAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQ 584
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELEELEAEL-EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  585 LSGSLKQKEKQLEEAAREldasrrDHAQQLATAAKAQETSLRERDAACQQLEALEKEkaakLEILQQQLQAANEAQDSAQ 664
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELK------ELQAELEELEEELEELQEELERLEEALEELREE----LEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  665 NSVTQAQREKAELSQKVEELHALIEAAHQeqceAQTQVAALEARLKAEQQKATEREKVAQEKaqLQEQLWSLEESLKITK 744
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKNQSG----LSGILGVLSELISVDEGYEAAIEAALGGR--LQAVVVENLNAAKKAI 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  745 GSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQER---KELEEEKAKRRGLGVQLqqLAETHQAETKALRQELAKA 821
Cdd:TIGR02168  563 AFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLgvaKDLVKFDPKLRKALSYL--LGGVLVVDDLDNALELAKK 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  822 RTSNNMaereveLLVKEVKTWRKRYedsqqgeTQYGLQEQLTTLKEEYEKSCQELRETKEKMagieahselqigqhQSEL 901
Cdd:TIGR02168  641 LRPGYR------IVTLDGDLVRPGG-------VITGGSAKTNSSILERRREIEELEEKIEEL--------------EEKI 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  902 AQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELL-----KEPPKTRDRES 976
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTeleaeIEELEERLEEA 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  977 EWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEaDLALEKAAKAE 1056
Cdd:TIGR02168  774 EEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE-DLEEQIEELSE 852

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1057 LEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQS 1131
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927
PTZ00121 PTZ00121
MAEBL; Provisional
 688-1536 1.82e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 89.82  E-value: 1.82e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  688 IEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcRAAAALEEHQhhise 767
Cdd:PTZ00121  1052 IDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEAR-KAEEAKKKAE----- 1125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  768 meaESRSLAEQHKQE--RKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRkR 845
Cdd:PTZ00121  1126 ---DARKAEEARKAEdaRKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDAR-K 1201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  846 YEDSQQGETQYGLQEqltTLKEEYEKSCQELRETKEkmagieahselqigqhqselAQLHANLARALQQVQEKENRAQKL 925
Cdd:PTZ00121  1202 AEAARKAEEERKAEE---ARKAEDAKKAEAVKKAEE--------------------AKKDAEEAKKAEEERNNEEIRKFE 1258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  926 ADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLcstqaalramEREAEQMG 1005
Cdd:PTZ00121  1259 EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEA----------KKKAEEAK 1328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1006 TELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADlalekAAKAELEMRLQNALNEQQAEFANLQEALSRAlsE 1085
Cdd:PTZ00121  1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA-----EKKKEEAKKKADAAKKKAEEKKKADEAKKKA--E 1401

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1086 KEGKDQELSKLCEQEAVQRMELKEllQTVEQLKAQLAKKEKEQQQSARGAsgenasgmgtqseavgKMEALRAKVSKLEQ 1165
Cdd:PTZ00121  1402 EDKKKADELKKAAAAKKKADEAKK--KAEEKKKADEAKKKAEEAKKADEA----------------KKKAEEAKKAEEAK 1463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1166 QCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRElatlRAKAQDHSKAEEEWKAQVA 1245
Cdd:PTZ00121  1464 KKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE----AKKADEAKKAEEAKKADEA 1539

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1246 RgQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEV 1325
Cdd:PTZ00121  1540 K-KAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1326 QSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQalsalqlehtstqalvsellpakhlcqqlQAEQ 1405
Cdd:PTZ00121  1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE-----------------------------EAKK 1669

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1406 VAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAE---KASYAEQLSMLKKAHGLLAEEN 1482
Cdd:PTZ00121  1670 AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAeeeNKIKAEEAKKEAEEDKKKAEEA 1749

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1196773644 1483 RGLGERANLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHEL 1536
Cdd:PTZ00121  1750 KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDI 1803
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 933-1714 3.05e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.49  E-value: 3.05e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  933 QEKMAATSKEVARLEALVRKAGEQQETASL--ELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEK 1010
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERqaEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1011 LRAALMESQGQQQEERGQqereVARLTQERGQAEADLALEKAAKAELEMRLQnalnEQQAEFANLQEALSRALSEKEGKD 1090
Cdd:TIGR02168  258 LTAELQELEEKLEELRLE----VSELEEEIEELQKELYALANEISRLEQQKQ----ILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1091 QELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENAsgmgtqseavgKMEALRAKVSKLEQQCQQQ 1170
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE-----------QLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1171 QEEADSLARSLESERAFHVERDRALETLQGQLEEKARELgySQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQE 1250
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQA 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1251 AVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEerlRLLQ-METASNSARAAErsSALREEVQSL- 1328
Cdd:TIGR02168  477 LDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILG---VLSElISVDEGYEAAIE--AALGGRLQAVv 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1329 REEVEKQRAASENLRQELASQAERAEE---LGQELKAWQEKFFQKEQALSALQLEHTST----QALVSELLPAKHLCQQL 1401
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNELGRVTFLPLdsiKGTEIQGNDREILKNIEGFLGVAKDLVKFdpklRKALSYLLGGVLVVDDL 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1402 Q-AEQVAAEKRHREE---LEQSKQAAGGLRTElMRAQRELG------ELVPLRQKVAEQERAAQQLRAEKASYAEQLSML 1471
Cdd:TIGR02168  632 DnALELAKKLRPGYRivtLDGDLVRPGGVITG-GSAKTNSSilerrrEIEELEEKIEELEEKIAELEKALAELRKELEEL 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1472 KKAhgllaeenrglGERANLGRQFLEVELDQAREKYIQELAAVRgdaetRLAEMRQEVQSTTHELEVMTAKYEGAKVKVL 1551
Cdd:TIGR02168  711 EEE-----------LEQLRKELEELSRQISALRKDLARLEAEVE-----QLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1552 EERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQM 1631
Cdd:TIGR02168  775 EELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1632 EKAKTHYDAKKQQNQELQEQLQGL----EQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHA 1707
Cdd:TIGR02168  855 ESLAAEIEELEELIEELESELEALlnerASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL 934


                   ....*..
gi 1196773644 1708 DQQLREL 1714
Cdd:TIGR02168  935 EVRIDNL 941
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 765-1673 1.92e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.73  E-value: 1.92e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  765 ISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLA-ETHQAET-KALRQELAKARTSNNMaeREVELLVKEVKTW 842
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRrEREKAERyQALLKEKREYEGYELL--KEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  843 RKRYEDSQqgETQYGLQEQLTTLKEEYEKSCQELRETKEKmagIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRA 922
Cdd:TIGR02169  243 ERQLASLE--EELEKLTEEISELEKRLEEIEQLLEELNKK---IKDLGEEEQLRVKEKIGELEAEIASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  923 QKLADDLSTLQEKMaatSKEVARLEALVRKAGEQQetasleLLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAE 1002
Cdd:TIGR02169  318 EDAEERLAKLEAEI---DKLLAEIEELEREIEEER------KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1003 QMGTELEKLRAALMESQGQQQEERGQQErevaRLTQERGQAEADLALEKAAKAELEMRLQnalnEQQAEFANLQEALSRA 1082
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELQ----RLSEELADLNAAIAGIEAKINELEEEKE----DKALEIKKQEWKLEQL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1083 LSEKEGKDQELSKLceqeavqRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASgmgtqseavgkMEALRAKVSK 1162
Cdd:TIGR02169  461 AADLSKYEQELYDL-------KEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAV-----------EEVLKASIQG 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1163 LEQQCQQQQEEADSLARSLESE-----RAFHVERD----RALETLqgqleeKARELGYSQ----AASASAQRELATLRAK 1229
Cdd:TIGR02169  523 VHGTVAQLGSVGERYATAIEVAagnrlNNVVVEDDavakEAIELL------KRRKAGRATflplNKMRDERRDLSILSED 596

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1230 -----AQDHSKAEEEWKAQVArgqqEAVRKGSLISSLEEEVSILNRQvlekegeskelkRLVIAESEKSQKLEerlrllQ 1304
Cdd:TIGR02169  597 gvigfAVDLVEFDPKYEPAFK----YVFGDTLVVEDIEAARRLMGKY------------RMVTLEGELFEKSG------A 654

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1305 METASNSARAAE-RSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTS 1383
Cdd:TIGR02169  655 MTGGSRAPRGGIlFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEK 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1384 TQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGelvplRQKVAEQERAAQQLRAEKAS 1463
Cdd:TIGR02169  735 LKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS-----HSRIPEIQAELSKLEEEVSR 809

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1464 YAEQLSMLKkahgllAEENRGLGERANLgrqfleveldqarEKYIQELAAVRGDAETRLAEMRQEVQSTTHELEvmtaky 1543
Cdd:TIGR02169  810 IEARLREIE------QKLNRLTLEKEYL-------------EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE------ 864

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1544 egakvkvleerqRFQEERQKLTAQVEELSKKLADYdqaskvqQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQA 1623
Cdd:TIGR02169  865 ------------ELEEELEELEAALRDLESRLGDL-------KKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1624 AEHYKVQMekakTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLG 1673
Cdd:TIGR02169  926 LEALEEEL----SEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALE 971
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 244-943 3.18e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.95  E-value: 3.18e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  244 QMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRL--ALLNEKQAASPLEPR------ELEELRGKNE 315
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkELYALANEISRLEQQkqilreRLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  316 SLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEH---SKATQQWVEKQAHLE 392
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetlRSKVAQLELQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  393 KELSTALQDKKCLEEKNEILQGKLSQLEERL--AQLPESPRQ--EKGEVLGDVL---------------QLESLKQEAAT 453
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLeeAELKELQAEleELEEELEELQeelerleealeelreELEEAEQALDA 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  454 LATNNTQLQARVEMLENEQGQKE------AQLLGERSHFEEEKQQLASLIT---------------NLQSSI-SNLSQAK 511
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLEgfsegvKALLKNQSGLSGILGVLSELISvdegyeaaieaalggRLQAVVvENLNAAK 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  512 EELE-----------------------QASQAQGAKLNAQVASLTAELTTLSATLQQ----------------------- 545
Cdd:TIGR02168  560 KAIAflkqnelgrvtflpldsikgteiQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvddldnalelak 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  546 ----------QDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAA----------RELDA 605
Cdd:TIGR02168  640 klrpgyrivtLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRkeleeleeelEQLRK 719

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  606 SRRDHAQQLAtaakAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELH 685
Cdd:TIGR02168  720 ELEELSRQIS----ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  686 ALIEAAHQEQCEAQTQVAALEARLkaeQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEekcrAAAALEEHQHHI 765
Cdd:TIGR02168  796 EELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRLEDLEEQIEELSEDIES----LAAEIEELEELI 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  766 SEMEAEsrslAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVEllvkevktwrkr 845
Cdd:TIGR02168  869 EELESE----LEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE------------ 932

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  846 yedsqqgETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHA-NLArALQQVQEKENR--- 921
Cdd:TIGR02168  933 -------GLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvNLA-AIEEYEELKERydf 1004

                          810       820
                   ....*....|....*....|....*.
gi 1196773644  922 --AQK--LADDLSTLQEKMAATSKEV 943
Cdd:TIGR02168 1005 ltAQKedLTEAKETLEEAIEEIDREA 1030
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 681-1580 1.98e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.26  E-value: 1.98e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  681 VEELHALIEAAHQEQCEAQTQVAALEARLKaeqQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEE 760
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIID---EKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  761 HQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELakartsnnmaEREVELLVKEVK 840
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGEL----------EAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  841 TWRKRYEDSQqgETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAhselqigqhqsELAQLHANLARALQQVQEKEN 920
Cdd:TIGR02169  312 EKERELEDAE--ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE-----------EYAELKEELEDLRAELEEVDK 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  921 RAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELlkeppktrdresewveEQQGQQLCSTQAALRAMERE 1000
Cdd:TIGR02169  379 EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL----------------ADLNAAIAGIEAKINELEEE 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1001 AEQMGTELEKLRAALMesqgqqqeergqqerevaRLTQERGQAEADLALEKAAKAELEMRLqnalneqqaefanlqEALS 1080
Cdd:TIGR02169  443 KEDKALEIKKQEWKLE------------------QLAADLSKYEQELYDLKEEYDRVEKEL---------------SKLQ 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1081 RALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGK--MEALRA 1158
Cdd:TIGR02169  490 RELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKeaIELLKR 569

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1159 K---------VSKLEQQCQQQQEEADS----------------------------LARSLESERAfHVERDRaLETLQGQ 1201
Cdd:TIGR02169  570 RkagratflpLNKMRDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgdtlVVEDIEAARR-LMGKYR-MVTLEGE 647

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1202 LEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKE 1281
Cdd:TIGR02169  648 LFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ 727

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1282 LKRLVIAESEKSQKLEERLRLLQMETASNSARAAErssaLREEVQSLREEVEKQRAASENLRQELASQ-----AERAEEL 1356
Cdd:TIGR02169  728 LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE----LEARIEELEEDLHKLEEALNDLEARLSHSripeiQAELSKL 803

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1357 GQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRE 1436
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQEL-------QEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA 876

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1437 LGELVPLRQKVAEQ-ERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGeraNLGRQFLEVELDQAREKYIQELAAVR 1515
Cdd:TIGR02169  877 LRDLESRLGDLKKErDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE---ALEEELSEIEDPKGEDEEIPEEELSL 953

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1516 GDaetrLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADYDQ 1580
Cdd:TIGR02169  954 ED----VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
PTZ00121 PTZ00121
MAEBL; Provisional
 1184-1748 2.51e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 76.33  E-value: 2.51e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1184 ERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELAtlRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEE 1263
Cdd:PTZ00121  1061 EAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAE--EAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAED 1138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1264 EVSIlnrqvlEKEGESKELKRLVIA-ESEKSQKLEERLRLLQMETASNSARAAERSSAlrEEVQSLRE--EVEKQRAASE 1340
Cdd:PTZ00121  1139 ARKA------EEARKAEDAKRVEIArKAEDARKAEEARKAEDAKKAEAARKAEEVRKA--EELRKAEDarKAEAARKAEE 1210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1341 NLRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcQQLQAEQVAAEKRHREEL---E 1417
Cdd:PTZ00121  1211 ERKAEEARKAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF--ARRQAAIKAEEARKADELkkaE 1287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1418 QSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLE 1497
Cdd:PTZ00121  1288 EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE 1367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1498 V-ELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTaKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLA 1576
Cdd:PTZ00121  1368 AaEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELK-KAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA 1446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1577 D-----YDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQ 1651
Cdd:PTZ00121  1447 DeakkkAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1652 LQGLEQLQKENKELRAEAERLGQELQQA-----GLKTKEAEQTCRHLTAQVRSL-EAQVAHADQQLRELGKFQVASDALK 1725
Cdd:PTZ00121  1527 AKKAEEAKKADEAKKAEEKKKADELKKAeelkkAEEKKKAEEAKKAEEDKNMALrKAEEAKKAEEARIEEVMKLYEEEKK 1606

                          570       580
                   ....*....|....*....|...
gi 1196773644 1726 SREPQAKPQLDLSIDSLDLSCEE 1748
Cdd:PTZ00121  1607 MKAEEAKKAEEAKIKAEELKKAE 1629
PTZ00121 PTZ00121
MAEBL; Provisional
 1082-1732 2.84e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.95  E-value: 2.84e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1082 ALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQL-KAQLAKKEKEQQQSARGASGENASGMGTQSEAvgkMEALRAKV 1160
Cdd:PTZ00121  1092 ATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAKRVEIARKA---EDARKAEE 1168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1161 SKleqqcqqqqeEADSLARSLESERAFHVERDRALEtlqgqleeKARELGYSQAASASAQRELATLRAKAQDHSKAEEEW 1240
Cdd:PTZ00121  1169 AR----------KAEDAKKAEAARKAEEVRKAEELR--------KAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVK 1230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1241 KAQVARGQQEAVRKGslisslEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEErLRLLQMETASNSARAAERssa 1320
Cdd:PTZ00121  1231 KAEEAKKDAEEAKKA------EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE-LKKAEEKKKADEAKKAEE--- 1300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1321 lREEVQSLREEVEKQRAASENLR--QELASQAERAEELGQELKAWQEKFFQKEQAlSALQLEHTSTQALVSELLPAKHLC 1398
Cdd:PTZ00121  1301 -KKKADEAKKKAEEAKKADEAKKkaEEAKKKADAAKKKAEEAKKAAEAAKAEAEA-AADEAEAAEEKAEAAEKKKEEAKK 1378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1399 QQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKvAEQERAAQQLRaEKASYAEQLSMLKKAhgll 1478
Cdd:PTZ00121  1379 KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKK-AEEKKKADEAK-KKAEEAKKADEAKKK---- 1452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1479 AEENRGLGEranlgrqfleveldqarekyiqelaAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQ 1558
Cdd:PTZ00121  1453 AEEAKKAEE-------------------------AKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAE 1507

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1559 EERQKLTAQVEELSKKLadyDQASKVQQQKlKAFQAQGGESQQEAQRLQtqlNELQVQLSQKEQAAEHYKVQMEKAKTHY 1638
Cdd:PTZ00121  1508 AKKKADEAKKAEEAKKA---DEAKKAEEAK-KADEAKKAEEKKKADELK---KAEELKKAEEKKKAEEAKKAEEDKNMAL 1580

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1639 DAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRELGKFQ 1718
Cdd:PTZ00121  1581 RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENK 1660

                          650
                   ....*....|....
gi 1196773644 1719 VASDALKSREPQAK 1732
Cdd:PTZ00121  1661 IKAAEEAKKAEEDK 1674
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1035-1743 5.30e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.71  E-value: 5.30e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1035 RLTQERGQAEADLALE--KAAKAELEmRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQ 1112
Cdd:TIGR02168  217 ELKAELRELELALLVLrlEELREELE-ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1113 TVEQLKAQLakkeKEQQQSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERD 1192
Cdd:TIGR02168  296 EISRLEQQK----QILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1193 RALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGslISSLEEEVSILNRQV 1272
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1273 LEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAerssalreevqSLREEVEKQRAASENLRQELASQAER 1352
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD-----------SLERLQENLEGFSEGVKALLKNQSGL 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1353 AEELGQ--ELKAWQEKFfqkEQALSALQLEHTstQALVSELLPAKHLCQQLQAeQVAAEKRHREELEQSK--QAAGGLRT 1428
Cdd:TIGR02168  519 SGILGVlsELISVDEGY---EAAIEAALGGRL--QAVVVENLNAAKKAIAFLK-QNELGRVTFLPLDSIKgtEIQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1429 ELMRAQRELGELVPLRQKVAEQERAAQQLRAEKA---SYAEQLSMLKK----------------AHGLLAeenrGLGERA 1489
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvdDLDNALELAKKlrpgyrivtldgdlvrPGGVIT----GGSAKT 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1490 NLGRQFLEVELDQAREKyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEER---QRFQEERQKLTA 1566
Cdd:TIGR02168  669 NSSILERRREIEELEEK-IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkdlARLEAEVEQLEE 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1567 QVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEhyKVQMEKAKTHYDAkkqqnq 1646
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD--ELRAELTLLNEEA------ 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1647 elQEQLQGLEQLQKENKELRAEAERLGQELqqaglktKEAEQTCRHLTAQVRSLEAQVAHADQQLRELGKFQVASDALKS 1726
Cdd:TIGR02168  820 --ANLRERLESLERRIAATERRLEDLEEQI-------EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          730
                   ....*....|....*..
gi 1196773644 1727 REPQAKPQLDLSIDSLD 1743
Cdd:TIGR02168  891 LLRSELEELSEELRELE 907
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 633-1454 1.68e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 1.68e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  633 QQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAE 712
Cdd:TIGR02169  198 QQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  713 QQKAteREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRaaaaLEEHQHHISEMEAESRSLAEQHKQERKELEEEKAK 792
Cdd:TIGR02169  278 NKKI--KDLGEEEQLRVKEKIGELEAEIASLERSIAEKERE----LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKR 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  793 RRGLGVQLQQLaethQAETKALRQELAKARTSNNMAEREVELLVKEV-KTWRKRYEdsqqgetqygLQEQLTTLKEEYEK 871
Cdd:TIGR02169  352 RDKLTEEYAEL----KEELEDLRAELEEVDKEFAETRDELKDYREKLeKLKREINE----------LKRELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  872 SCQELRETKEKMAGIEAhselqigqhqsELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVR 951
Cdd:TIGR02169  418 LSEELADLNAAIAGIEA-----------KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  952 KAgeQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKlrAALMESQGQQQEERGQQER 1031
Cdd:TIGR02169  487 KL--QRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEV--AAGNRLNNVVVEDDAVAKE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1032 EVARLTQERGQAEADLALEKAAKAELEMR-------LQNALN----EQQAE------------FANLQEA---------- 1078
Cdd:TIGR02169  563 AIELLKRRKAGRATFLPLNKMRDERRDLSilsedgvIGFAVDlvefDPKYEpafkyvfgdtlvVEDIEAArrlmgkyrmv 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1079 -LSRALSEKEG---------KDQELSKLCEQEAVQRMelKELLQTVEQLKAQLAKKEKEQQQSARGASGEnasgmgtQSE 1148
Cdd:TIGR02169  643 tLEGELFEKSGamtggsrapRGGILFSRSEPAELQRL--RERLEGLKRELSSLQSELRRIENRLDELSQE-------LSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1149 AVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELA---- 1224
Cdd:TIGR02169  714 ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLShsri 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1225 -TLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKR---LVIAESEKSQ----KL 1296
Cdd:TIGR02169  794 pEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKeieNLNGKKEELEeeleEL 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1297 EERLRLLQMEtasnsaraaerssalREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAwqeKFFQKEQALSA 1376
Cdd:TIGR02169  874 EAALRDLESR---------------LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA---KLEALEEELSE 935

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1377 LQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEK------RHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQ 1450
Cdd:TIGR02169  936 IEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRAlepvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015


                   ....
gi 1196773644 1451 ERAA 1454
Cdd:TIGR02169 1016 KREV 1019
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
593-1096 4.09e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 71.87  E-value: 4.09e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  593 EKQLEEAARELDASRRDH--AQQLATAAKAQETSLRERDAACQQLEALEKEK--------AAKLEILQQQLQAANEAQDS 662
Cdd:COG4913    220 EPDTFEAADALVEHFDDLerAHEALEDAREQIELLEPIRELAERYAAARERLaeleylraALRLWFAQRRLELLEAELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  663 AQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQ-VAALEARLKAEQQkatEREKVAQEKAQLQEQLWSLEESLK 741
Cdd:COG4913    300 LRAELARLEAELERLEARLDALREELDELEAQIRGNGGDrLEQLEREIERLER---ELEERERRRARLEALLAALGLPLP 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  742 ITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRglgvQLQQLAETHQAETKALRQELAKA 821
Cdd:COG4913    377 ASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIA----SLERRKSNIPARLLALRDALAEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  822 RtsnNMAEREV----ELLvkEVKT----WR------------------KRYEDSQQGETQYGLQEQLTTLKEeyekscqE 875
Cdd:COG4913    453 L---GLDEAELpfvgELI--EVRPeeerWRgaiervlggfaltllvppEHYAAALRWVNRLHLRGRLVYERV-------R 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  876 LRETKEKMAGIEAHS---ELQIGQH------QSELA-------------------------QLHANLAR----------- 910
Cdd:COG4913    521 TGLPDPERPRLDPDSlagKLDFKPHpfrawlEAELGrrfdyvcvdspeelrrhpraitragQVKGNGTRhekddrrrirs 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  911 -------ALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELlkEPPKTRDRESEWveEQQ 983
Cdd:COG4913    601 ryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEI--DVASAEREIAEL--EAE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  984 GQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAA-KAELEMRLQ 1062
Cdd:COG4913    677 LERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLElRALLEERFA 756

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1196773644 1063 NALNEQQAE--FANLQEALSRALSEKEGKDQELSKL 1096
Cdd:COG4913    757 AALGDAVERelRENLEERIDALRARLNRAEEELERA 792
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1086-1714 5.40e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.63  E-value: 5.40e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1086 KEGKDQELSKLCE-QEAVQRME--LKELLQTVEQLKAQLAKKEKEQQQSARGASGENASgmgtqseAVGKMEALRAKVSK 1162
Cdd:TIGR02168  171 KERRKETERKLERtRENLDRLEdiLNELERQLKSLERQAEKAERYKELKAELRELELAL-------LVLRLEELREELEE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1163 LEQQCQQQQEEADSLAR-------SLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSK 1235
Cdd:TIGR02168  244 LQEELKEAEEELEELTAelqeleeKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1236 AEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSA--- 1312
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNeie 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1313 RAAERSSALREEVQSLREEVE-----KQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQAL 1387
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEellkkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1388 VSELLPAKHLCQQLQAEQ------VAAEKRHREELEQS------------------------------------------ 1419
Cdd:TIGR02168  484 LAQLQARLDSLERLQENLegfsegVKALLKNQSGLSGIlgvlselisvdegyeaaieaalggrlqavvvenlnaakkaia 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1420 --KQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSM--------------LKKAHGLLAEENR 1483
Cdd:TIGR02168  564 flKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvddLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1484 GL-------------------GERANLGRQFLEVELDQAREKyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYE 1544
Cdd:TIGR02168  644 GYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEK-IEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1545 GAKVKVLEER---QRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKE 1621
Cdd:TIGR02168  723 ELSRQISALRkdlARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1622 QAAEhyKVQMEKAKTHYDA------KKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTA 1695
Cdd:TIGR02168  803 EALD--ELRAELTLLNEEAanlrerLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN 880

                          730
                   ....*....|....*....
gi 1196773644 1696 QVRSLEAQVAHADQQLREL 1714
Cdd:TIGR02168  881 ERASLEEALALLRSELEEL 899
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 379-1130 6.94e-12

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 71.16  E-value: 6.94e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  379 KATQQWVEKQAHLEKELSTALQDKKcLEEKNEilqgKLSQLEERLAQLPESPRQEKgevlgdvLQLESLKQEAATLATNN 458
Cdd:pfam02463  146 IIAMMKPERRLEIEEEAAGSRLKRK-KKEALK----KLIEETENLAELIIDLEELK-------LQELKLKEQAKKALEYY 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  459 TQLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTT 538
Cdd:pfam02463  214 QLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAK 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  539 LSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRrdhaQQLATAA 618
Cdd:pfam02463  294 EEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELE----KLQEKLE 369

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  619 KAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEA 698
Cdd:pfam02463  370 QLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEE 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  699 QTQVAALEARLKAEQQKAtEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQ 778
Cdd:pfam02463  450 KEELEKQELKLLKDELEL-KKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAH 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  779 HKQERKELEEEKAKRRGLGVQLQQLAETHQAETKA--LRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQY 856
Cdd:pfam02463  529 GRLGDLGVAVENYKVAISTAVIVEVSATADEVEERqkLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQL 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  857 GLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIG-QHQSELAQLHANLARALQQVQEKEnRAQKLADDLSTLQEK 935
Cdd:pfam02463  609 DKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGlRKGVSLEEGLAEKSEVKASLSELT-KELLEIQELQEKAES 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  936 MAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAAL 1015
Cdd:pfam02463  688 ELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKS 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1016 MESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAElEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSK 1095
Cdd:pfam02463  768 ELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEE-ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQ 846

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 1196773644 1096 LCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQ 1130
Cdd:pfam02463  847 KLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 578-1331 1.04e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 1.04e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  578 LRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEK---EKAAKLEILQQQLQ 654
Cdd:TIGR02169  196 KRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEeisELEKRLEEIEQLLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  655 AANEA-QDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEArlkaeqqkatEREKVAQEKAQLQEQL 733
Cdd:TIGR02169  276 ELNKKiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA----------EIDKLLAEIEELEREI 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  734 wsleESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQ---AE 810
Cdd:TIGR02169  346 ----EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQrlsEE 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  811 TKALRQELAKARTSNNMAEREVELLVKEVKTwrkryedsqqgetqygLQEQLTTLKEEYEKSCQELRETKEKMAGIEAhs 890
Cdd:TIGR02169  422 LADLNAAIAGIEAKINELEEEKEDKALEIKK----------------QEWKLEQLAADLSKYEQELYDLKEEYDRVEK-- 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  891 elQIGQHQSELAQLHANlARALQQVQEKENRAQKLAD-----------DLSTLQEKMAaTSKEVA---RLEALVRKAGEQ 956
Cdd:TIGR02169  484 --ELSKLQRELAEAEAQ-ARASEERVRGGRAVEEVLKasiqgvhgtvaQLGSVGERYA-TAIEVAagnRLNNVVVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  957 QETAsLELLKEPP----------KTRDRESE---------------WVEEQQGQQLCSTQA-----ALRAMEREAEQMG- 1005
Cdd:TIGR02169  560 AKEA-IELLKRRKagratflplnKMRDERRDlsilsedgvigfavdLVEFDPKYEPAFKYVfgdtlVVEDIEAARRLMGk 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1006 ------------------------TELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAE--ADLALEKAAKAELEM 1059
Cdd:TIGR02169  639 yrmvtlegelfeksgamtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEnrLDELSQELSDASRKI 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1060 RL----QNALNEQQAEFANLQEALSRALSEKEgkdQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGA 1135
Cdd:TIGR02169  719 GEiekeIEQLEQEEEKLKERLEELEEDLSSLE---QEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPE 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1136 SGENASGMGTQ-SEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQA 1214
Cdd:TIGR02169  796 IQAELSKLEEEvSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEA 875

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1215 ASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAE----- 1289
Cdd:TIGR02169  876 ALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsled 955

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*.
gi 1196773644 1290 -SEKSQKLEERLRLLQ---METASNSARAAERSSALREEVQSLREE 1331
Cdd:TIGR02169  956 vQAELQRVEEEIRALEpvnMLAIQEYEEVLKRLDELKEKRAKLEEE 1001
PTZ00121 PTZ00121
MAEBL; Provisional
 303-982 2.76e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.40  E-value: 2.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  303 EPRELEELRGKNESltfRLHETLKQCQDLK--TEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKA 380
Cdd:PTZ00121  1210 EERKAEEARKAEDA---KKAEAVKKAEEAKkdAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKA 1286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  381 TQQWVEKQAHLEKELSTALQDKKCLEEKNEILQGKlSQLEERLAQLPESprQEKGEVLGDVLQLESLKQEAATLATNNTQ 460
Cdd:PTZ00121  1287 EEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK-KKAEEAKKKADAA--KKKAEEAKKAAEAAKAEAEAAADEAEAAE 1363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  461 LQARVEMLENEQGQKEAQLLGERShfeEEKQQLASLITNLQssisnlsQAKEELEQASQAQGAKLNAQVASLTAELTTLS 540
Cdd:PTZ00121  1364 EKAEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAE-------EDKKKADELKKAAAAKKKADEAKKKAEEKKKA 1433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  541 ATLQQQDQELAGLKQQAQKKQAqlaqslqqqeqasqglRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKA 620
Cdd:PTZ00121  1434 DEAKKKAEEAKKADEAKKKAEE----------------AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKK 1497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  621 QETSLRERDAACQQLEALEKEKAAKLeilQQQLQAANEAQdSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQ----- 695
Cdd:PTZ00121  1498 KADEAKKAAEAKKKADEAKKAEEAKK---ADEAKKAEEAK-KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEakkae 1573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  696 --------------------CEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKitkgSLEEEKCRAA 755
Cdd:PTZ00121  1574 edknmalrkaeeakkaeearIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLK----KKEAEEKKKA 1649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  756 AALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELL 835
Cdd:PTZ00121  1650 EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK 1729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  836 VKEVKTWRKRYEDSQQGE---TQYGLQEQLTTLKEEYEKSCQELRetKEKMAGIEAHSELQIGQHQSELAQLHANLARAL 912
Cdd:PTZ00121  1730 IKAEEAKKEAEEDKKKAEeakKDEEEKKKIAHLKKEEEKKAEEIR--KEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNF 1807

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  913 QQVQEKENRAQKLADDlstLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQ 982
Cdd:PTZ00121  1808 ANIIEGGKEGNLVIND---SKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEK 1874
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 664-1011 3.07e-11

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 68.38  E-value: 3.07e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  664 QNSVTQAQREKAELSQKVEelhALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKIT 743
Cdd:pfam07888   33 QNRLEECLQERAELLQAQE---AANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSAS 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  744 KGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQ----------LQQLAETHQAETKA 813
Cdd:pfam07888  110 SEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQrkeeeaerkqLQAKLQQTEEELRS 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  814 LRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQY-GLQEQLTTLKEEYEKSCQE---LRETKEKMAGIEAH 889
Cdd:pfam07888  190 LSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENeALLEELRSLQERLNASERKvegLGEELSSMAAQRDR 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  890 SELQIGQHQSELAQLHANLARALQQVQEKENRAQK----LADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELL 965
Cdd:pfam07888  270 TQAELHQARLQAAQLTLQLADASLALREGRARWAQeretLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELG 349

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1196773644  966 KEPPKTRDRESEWVEEQQGQqlcstQAALRAMEREAEQMGTELEKL 1011
Cdd:pfam07888  350 REKDCNRVQLSESRRELQEL-----KASLRVAQKEKEQLQAEKQEL 390
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 244-953 5.97e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.17  E-value: 5.97e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  244 QMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRL-------------------ALLNEKQAASPLEP 304
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeqlrvkekigeleaeiASLERSIAEKEREL 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  305 RELEELRGKNESltfRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQ-- 382
Cdd:TIGR02169  318 EDAEERLAKLEA---EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREkl 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  383 -QWVEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQL 461
Cdd:TIGR02169  395 eKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  462 QARVEMLENEQGQKE---AQLLGERSHFEEEKQQLASLITNLQSSI-------SNLSQAKEELEQASQ-AQGAKLNAQVA 530
Cdd:TIGR02169  475 KEEYDRVEKELSKLQrelAEAEAQARASEERVRGGRAVEEVLKASIqgvhgtvAQLGSVGERYATAIEvAAGNRLNNVVV 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  531 S---------------------------LTAELTTLSA------------------------------TLQQQDQELAGL 553
Cdd:TIGR02169  555 EddavakeaiellkrrkagratflplnkMRDERRDLSIlsedgvigfavdlvefdpkyepafkyvfgdTLVVEDIEAARR 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  554 KQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAAR--ELDASRRDHAQQLATAAKAQETSLRERDAA 631
Cdd:TIGR02169  635 LMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERleGLKRELSSLQSELRRIENRLDELSQELSDA 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  632 CQQLEALEKEkaakLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKA 711
Cdd:TIGR02169  715 SRKIGEIEKE----IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  712 EQQkaterEKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEhqhhISEMEAESRSLAEQHKQERKELEEEKA 791
Cdd:TIGR02169  791 SRI-----PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE----IQELQEQRIDLKEQIKSIEKEIENLNG 861

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  792 KRRglgvQLQQLAETHQAETKALRQELAKartsnnmAEREVELLVKEVKTWRKRYEdsQQGETQYGLQEQLTTLKEEYEK 871
Cdd:TIGR02169  862 KKE----ELEEELEELEAALRDLESRLGD-------LKKERDELEAQLRELERKIE--ELEAQIEKKRKRLSELKAKLEA 928

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  872 SCQELRETKEKMAGIEAHS--ELQIGQHQSELAQLHANLA-------RALQQVQEKENRAQKLADDLSTLQEKMAATSKE 942
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEIPeeELSLEDVQAELQRVEEEIRalepvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILER 1008

                          810
                   ....*....|.
gi 1196773644  943 VARLEALVRKA 953
Cdd:TIGR02169 1009 IEEYEKKKREV 1019
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 360-927 8.16e-11

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 67.56  E-value: 8.16e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  360 ASNLQQLQGALNELTEEHSKATQQWVEKQAHLEKELSTALQDKKCLEEKNEIL-------------------------QG 414
Cdd:pfam12128  275 ASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALedqhgafldadietaaadqeqlpswQS 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  415 KLSQLEERLAQLPESprQEKGEVLGDVLQLESLKQEAATLATNNTQL----QARVEMLENEQGQKEA-------QLLGER 483
Cdd:pfam12128  355 ELENLEERLKALTGK--HQDVTAKYNRRRSKIKEQNNRDIAGIKDKLakirEARDRQLAVAEDDLQAleselreQLEAGK 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  484 SHFEEEKQQLASLITNLQSSIS----------NLSQAKEELEQASQAQGAKlNAQVASLTAELTTLSATLQQQDQELAGL 553
Cdd:pfam12128  433 LEFNEEEYRLKSRLGELKLRLNqatatpelllQLENFDERIERAREEQEAA-NAEVERLQSELRQARKRRDQASEALRQA 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  554 KQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLeeAARELdASRRDHAQQLATAAKAQETSLRERDAACQ 633
Cdd:pfam12128  512 SRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKV--ISPEL-LHRTDLDPEVWDGSVGGELNLYGVKLDLK 588

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  634 QLEAleKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQ 713
Cdd:pfam12128  589 RIDV--PEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEK 666

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  714 QKATerEKVAQEKAQLQEQLWSLEESLKitkgsleeekcraaAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKR 793
Cdd:pfam12128  667 DKKN--KALAERKDSANERLNSLEAQLK--------------QLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQ 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  794 RGLGVQ-LQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGE---TQYG--LQEQLTT--- 864
Cdd:pfam12128  731 LALLKAaIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRqevLRYFdwYQETWLQrrp 810

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1196773644  865 -LKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLAD 927
Cdd:pfam12128  811 rLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 389-1130 1.19e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 1.19e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  389 AHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLpespRQEKGEVLG-DVLQLESLKQEAatlatnnTQLQARVEM 467
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERL----RREREKAERyQALLKEKREYEG-------YELLKEKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  468 LENEQGQKEAQLlgerSHFEEEKQQLASLITNLQSSISN----LSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATL 543
Cdd:TIGR02169  235 LERQKEAIERQL----ASLEEELEKLTEEISELEKRLEEieqlLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSI 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  544 QQQDQELaglkqqaqkkqaqlaqslqqqeqasqglrhqvEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQE- 622
Cdd:TIGR02169  311 AEKEREL--------------------------------EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEe 358

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  623 --TSLRERDAACQQLEALEKEKAA---KLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCE 697
Cdd:TIGR02169  359 yaELKEELEDLRAELEEVDKEFAEtrdELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  698 AQTQVAALEARLKAEQQKateREKVAQEKAQLQEQLWSLEESLKItkgsLEEEkcraaaaLEEHQHHISEMEAESRSLAE 777
Cdd:TIGR02169  439 LEEEKEDKALEIKKQEWK---LEQLAADLSKYEQELYDLKEEYDR----VEKE-------LSKLQRELAEAEAQARASEE 504

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  778 QHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALrqELAKARTSNNM-------AEREVELLvKEVKTWR------- 843
Cdd:TIGR02169  505 RVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAI--EVAAGNRLNNVvveddavAKEAIELL-KRRKAGRatflpln 581

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  844 ----------------------------KRYE-------------DSQQGETQYGLQEQLTTLKEE-YEKS--------- 872
Cdd:TIGR02169  582 kmrderrdlsilsedgvigfavdlvefdPKYEpafkyvfgdtlvvEDIEAARRLMGKYRMVTLEGElFEKSgamtggsra 661

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  873 --------------CQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADD---------- 928
Cdd:TIGR02169  662 prggilfsrsepaeLQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEeeklkerlee 741

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  929 ----LSTLQEKMAATSKEVARLEAlvRKAGEQQETASLELLKEPPKTRDRESEWVE-EQQGQQLCSTQAALRAMEREAEQ 1003
Cdd:TIGR02169  742 leedLSSLEQEIENVKSELKELEA--RIEELEEDLHKLEEALNDLEARLSHSRIPEiQAELSKLEEEVSRIEARLREIEQ 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1004 MGTELEKLRAALMESQGQQQEERGQQEREVArltqERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRAL 1083
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIK----SIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELE 895

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*..
gi 1196773644 1084 SEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQ 1130
Cdd:TIGR02169  896 AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 263-1013 2.13e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 66.30  E-value: 2.13e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  263 ELELAEHRKL------------LTEKDAQISMMQQRIDRLALLNEKQAASplepreleeLRGKNESLTFRLhetlkqcQD 330
Cdd:pfam15921   58 EVELDSPRKIiaypgkehiervLEEYSHQVKDLQRRLNESNELHEKQKFY---------LRQSVIDLQTKL-------QE 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  331 LKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLE---KELSTALQDKKCLEE 407
Cdd:pfam15921  122 MQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  408 KNEILQGKLSQLEER---------LAQLPESPRQEKGEVLGDVLQLESLKQEAatlatnntqlQARVEMLENEQGQKEAQ 478
Cdd:pfam15921  202 KKIYEHDSMSTMHFRslgsaiskiLRELDTEISYLKGRIFPVEDQLEALKSES----------QNKIELLLQQHQDRIEQ 271

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  479 LLGER----SHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLK 554
Cdd:pfam15921  272 LISEHeveiTGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQL 351

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  555 QQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQL----EEAARELDasrRDHAQQLATAAKAQEtsLRERDA 630
Cdd:pfam15921  352 VLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELslekEQNKRLWD---RDTGNSITIDHLRRE--LDDRNM 426

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  631 ACQQLEALEK----EKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHA---LIEAAHQEQCEAQTQVA 703
Cdd:pfam15921  427 EVQRLEALLKamksECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAkkmTLESSERTVSDLTASLQ 506

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  704 ALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLE------EEKCRAAAALEEHQHHISEMEAESRSLAE 777
Cdd:pfam15921  507 EKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEalklqmAEKDKVIEILRQQIENMTQLVGQHGRTAG 586

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  778 QHKQERKELEEEKAKRRglgVQLQQL--------AETHQAETKALRQELAKARTSNNMAER---------EVELLVKEVK 840
Cdd:pfam15921  587 AMQVEKAQLEKEINDRR---LELQEFkilkdkkdAKIRELEARVSDLELEKVKLVNAGSERlravkdikqERDQLLNEVK 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  841 TWRKryedsqqgetqyglqeQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHanlaRALQQVQEKEN 920
Cdd:pfam15921  664 TSRN----------------ELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR----NTLKSMEGSDG 723

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  921 RAQKLAddlSTLQEKMAATSKEVARLEalvrkageqqetASLELLKEPPKTRDRESEWVEEQQGQqlcsTQAALRAMERE 1000
Cdd:pfam15921  724 HAMKVA---MGMQKQITAKRGQIDALQ------------SKIQFLEEAMTNANKEKHFLKEEKNK----LSQELSTVATE 784

                          810
                   ....*....|...
gi 1196773644 1001 AEQMGTELEKLRA 1013
Cdd:pfam15921  785 KNKMAGELEVLRS 797
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 249-1078 3.52e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 65.76  E-value: 3.52e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  249 KKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAASPLEPRELEELRGKNESLTFRLHETLKQC 328
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  329 QDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQqwvEKQAHLEKELSTALQDKKCLEEK 408
Cdd:pfam02463  260 IEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDE---EKLKESEKEKKKAEKELKKEKEE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  409 NEILQGKLSQLEERLAQLpespRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGERSHFEE 488
Cdd:pfam02463  337 IEELEKELKELEIKREAE----EEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  489 EKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSL 568
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  569 QQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETS-LRERDAACQQLEALEKEKAAKLE 647
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAvIVEVSATADEVEERQKLVRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  648 ILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKA 727
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  728 QLQEqlWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRrgLGVQLQQLAETH 807
Cdd:pfam02463  653 SLEE--GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLK--LEAEELLADRVQ 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  808 QAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIE 887
Cdd:pfam02463  729 EAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEE 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  888 AHSELQIGQHQSELAQLHANLARALQQVQEKENraQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKE 967
Cdd:pfam02463  809 ELKEEAELLEEEQLLIEQEEKIKEEELEELALE--LKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  968 PPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAAL-MESQGQQQEERGQQEREVARLTQERGQAEAD 1046
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEeEPEELLLEEADEKEKEENNKEEEEERNKRLL 966

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1196773644 1047 LALEKAAKAELEMRLQNALNEQQAEFANLQEA 1078
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 630-1158 6.85e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 64.86  E-value: 6.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  630 AACQQLEALEKEKAA-KLEILQQQLQAAN--EAQDSAQNSVTQAQREK-AELSQKVEELHALIEAAHQEQCEAQTQVAAL 705
Cdd:pfam12128  248 QEFNTLESAELRLSHlHFGYKSDETLIASrqEERQETSAELNQLLRTLdDQWKEKRDELNGELSAADAAVAKDRSELEAL 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  706 EARLKAEQQKATEREKVAQEKA-QLQEQLWSLEESLKitkgsleeekcraaAALEEHQHHISEMEAESRSLAEQHKQERK 784
Cdd:pfam12128  328 EDQHGAFLDADIETAAADQEQLpSWQSELENLEERLK--------------ALTGKHQDVTAKYNRRRSKIKEQNNRDIA 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  785 ELEEEKAKRRGLGVQLQQLAETH-QAETKALRQELAKARTSNNMAEREVELLVKEVKTwrkryedsQQGETQYglQEQLT 863
Cdd:pfam12128  394 GIKDKLAKIREARDRQLAVAEDDlQALESELREQLEAGKLEFNEEEYRLKSRLGELKL--------RLNQATA--TPELL 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  864 TLKEEYEKSCQELRETKEK-MAGIEAHselqigqhQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKE 942
Cdd:pfam12128  464 LQLENFDERIERAREEQEAaNAEVERL--------QSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGT 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  943 VarLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRAMEREAE---QMGTELEKLRAALMESQ 1019
Cdd:pfam12128  536 L--LHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPewaASEEELRERLDKAEEAL 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1020 GQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRalsEKEGKDQELSKLceq 1099
Cdd:pfam12128  614 QSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAE---RKDSANERLNSL--- 687

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1196773644 1100 EAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKMEALRA 1158
Cdd:pfam12128  688 EAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAK 746
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 246-744 7.64e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 64.27  E-value: 7.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  246 RRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAaspLEPRELEELRGKNESLTFRLHETL 325
Cdd:TIGR04523  162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNK---SLESQISELKKQNNQLKDNIEKKQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  326 KQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWV----EKQAHLEKELSTALQD 401
Cdd:TIGR04523  239 QEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISdlnnQKEQDWNKELKSELKN 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  402 KkclEEKNEILQGKLSQLEERLAQLPEsprqekgevlgdvlQLESLKQEAATLATNNTQLQARVEmlenEQGQKEAQLLG 481
Cdd:TIGR04523  319 Q---EKKLEEIQNQISQNNKIISQLNE--------------QISQLKKELTNSESENSEKQRELE----EKQNEIEKLKK 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  482 ERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQ---ASQAQGAKLNAQVASLTAELTTLSAT---LQQQDQELAGLKQ 555
Cdd:TIGR04523  378 ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEqikKLQQEKELLEKEIERLKETIIKNNSEikdLTNQDSVKELIIK 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  556 QAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEeaarELDASRRDHAQQLATAAKAQETSLRERdaacQQL 635
Cdd:TIGR04523  458 NLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELK----KLNEEKKELEEKVKDLTKKISSLKEKI----EKL 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  636 EALEKEKAAKLEILQQQLQAANEAQDSaqnsvTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVaalearlkaeQQK 715
Cdd:TIGR04523  530 ESEKKEKESKISDLEDELNKDDFELKK-----ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELI----------DQK 594

                          490       500
                   ....*....|....*....|....*....
gi 1196773644  716 ATEREKVAQEKAQLQEQLWSLEESLKITK 744
Cdd:TIGR04523  595 EKEKKDLIKEIEEKEKKISSLEKELEKAK 623
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1448-1728 9.05e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 9.05e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1448 AEQERAAQQLRAEKASYaEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQA-REKYIQELAAVRGDAETRLAEMR 1526
Cdd:COG1196    209 AEKAERYRELKEELKEL-EAELLLLKLRELEAELEELEAELEELEAELEELEAELAeLEAELEELRLELEELELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1527 QEVQSTTHELEvmtaKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRL 1606
Cdd:COG1196    288 AEEYELLAELA----RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1607 QTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEA 1686
Cdd:COG1196    364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1196773644 1687 EQTCRHLTAQVRSLEAQVAHADQQLRELGKFQVASDALKSRE 1728
Cdd:COG1196    444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
470-959 1.27e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.52  E-value: 1.27e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  470 NEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQgAKLNAQVASLTAELTTLSATLQQQDQ- 548
Cdd:PRK02224   209 NGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEI-EDLRETIAETEREREELAEEVRDLREr 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  549 ---------ELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLE---EAARELD---ASRRDHAQQ 613
Cdd:PRK02224   288 leeleeerdDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAEslrEDADDLEeraEELREEAAE 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  614 LATAAKAQETSLRERDAacqQLEALEKE----------KAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEE 683
Cdd:PRK02224   368 LESELEEAREAVEDRRE---EIEELEEEieelrerfgdAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  684 LHALIEAAHQEQC----EAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKG--SLEEEKCRAAAA 757
Cdd:PRK02224   445 AEALLEAGKCPECgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRieRLEERREDLEEL 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  758 LEEHQHHIsemeAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVk 837
Cdd:PRK02224   525 IAERRETI----EEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLA- 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  838 evktwrKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAgiEAHSELQIGQHQSELAQLH---ANLARALQQ 914
Cdd:PRK02224   600 ------AIADAEDEIERLREKREALAELNDERRERLAEKRERKRELE--AEFDEARIEEAREDKERAEeylEQVEEKLDE 671

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1196773644  915 VQEKENRAQKLA-------DDLSTLQEKMAATSKEVARLEALVRKAGEQQET 959
Cdd:PRK02224   672 LREERDDLQAEIgavenelEELEELRERREALENRVEALEALYDEAEELESM 723
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 305-1117 1.41e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.55  E-value: 1.41e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  305 RELEELRGKNESLTFRLHETLKQCQDLKTEKG--------------------------------QMDRKINQLSEENGDL 352
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRREREkaeryqallkekreyegyellkekealerqkeAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  353 SFKLREFASNLQQLQGALNELTEEHSKATQqwvEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQ 432
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGE---EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  433 EKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKE 512
Cdd:TIGR02169  334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  513 ELEQASQaQGAKLNAQVASLTAELTTLSATLQQQDQELAglkqqaqkkqaQLAQSLQQQEQASQGLRHQVEQLSGSLKQK 592
Cdd:TIGR02169  414 ELQRLSE-ELADLNAAIAGIEAKINELEEEKEDKALEIK-----------KQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  593 EKQLEEAARELDA--SRRDHAQQLATAAKAQETSLRERD----AACQQLEALEKEKAAKLEI-LQQQLQAANEAQDS-AQ 664
Cdd:TIGR02169  482 EKELSKLQRELAEaeAQARASEERVRGGRAVEEVLKASIqgvhGTVAQLGSVGERYATAIEVaAGNRLNNVVVEDDAvAK 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  665 NSVTQAQREKAELS-----QKVEELHALIEAAHQE----------QCEAQTQVA---ALEARLKAEQQKATEREKVAQEK 726
Cdd:TIGR02169  562 EAIELLKRRKAGRAtflplNKMRDERRDLSILSEDgvigfavdlvEFDPKYEPAfkyVFGDTLVVEDIEAARRLMGKYRM 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  727 AQLQEQLwsLEESLKITKGSleeekcRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAET 806
Cdd:TIGR02169  642 VTLEGEL--FEKSGAMTGGS------RAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  807 HQAETKALRQELakartsnNMAEREVELLVKEVKTWRKRYEDSQQGETQYglQEQLTTLKEEYEKSCQELRETKEKMAGI 886
Cdd:TIGR02169  714 ASRKIGEIEKEI-------EQLEQEEEKLKERLEELEEDLSSLEQEIENV--KSELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  887 EAH-SELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAatSKEVARLEALVRKAGEQQETASLELL 965
Cdd:TIGR02169  785 EARlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ--ELQEQRIDLKEQIKSIEKEIENLNGK 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  966 KEPPKTRDRESEWVEEQQGQQLC-------STQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQ 1038
Cdd:TIGR02169  863 KEELEEELEELEAALRDLESRLGdlkkerdELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1196773644 1039 ERGQAEADLALEKaakaelemrLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQL 1117
Cdd:TIGR02169  943 DEEIPEEELSLED---------VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1035-1701 2.10e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 2.10e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1035 RLTQERGQAEADLALeKAAKAELEMR-LQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLceqeavqRMELKELLQT 1113
Cdd:TIGR02169  202 RLRREREKAERYQAL-LKEKREYEGYeLLKEKEALERQKEAIERQLASLEEELEKLTEEISEL-------EKRLEEIEQL 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1114 VEQLKAQLAKKEKEQ----QQSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESER---- 1185
Cdd:TIGR02169  274 LEELNKKIKDLGEEEqlrvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERkrrd 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1186 ---AFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAE-------EEWKAQVARGQQEAVRKG 1255
Cdd:TIGR02169  354 kltEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELdrlqeelQRLSEELADLNAAIAGIE 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1256 SLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASnsarAAERSSALREEVQSLREEVEKQ 1335
Cdd:TIGR02169  434 AKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSK----LQRELAEAEAQARASEERVRGG 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1336 RAASENLRQELA------------------------------------SQAERAEELGQELKAWQEKFFQ-KEQALSALQ 1378
Cdd:TIGR02169  510 RAVEEVLKASIQgvhgtvaqlgsvgeryataievaagnrlnnvvveddAVAKEAIELLKRRKAGRATFLPlNKMRDERRD 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1379 LEHTSTQALVSELLPAKHLCQQLQA------------EQVAAEKRHR----------EELEQSKQAAGGLRT-------- 1428
Cdd:TIGR02169  590 LSILSEDGVIGFAVDLVEFDPKYEPafkyvfgdtlvvEDIEAARRLMgkyrmvtlegELFEKSGAMTGGSRAprggilfs 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1429 -----ELMRAQRELG----ELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvE 1499
Cdd:TIGR02169  670 rsepaELQRLRERLEglkrELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS-S 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1500 LDQAREKYIQELAAVRGdaetRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEE-RQKLTAQVEELSKKLADY 1578
Cdd:TIGR02169  749 LEQEIENVKSELKELEA----RIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEeVSRIEARLREIEQKLNRL 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1579 DQASKVQQQKL--------------KAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQ 1644
Cdd:TIGR02169  825 TLEKEYLEKEIqelqeqridlkeqiKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERK 904

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1196773644 1645 NQELQEQLQGLEQLQKENKELRAEAE----------RLGQELQQAGLKTKEAEQTCRHLTAQVRSLE 1701
Cdd:TIGR02169  905 IEELEAQIEKKRKRLSELKAKLEALEeelseiedpkGEDEEIPEEELSLEDVQAELQRVEEEIRALE 971
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 435-680 2.38e-09

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 62.93  E-value: 2.38e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  435 GEVLGDVLQLESLKQEAATLATNNTQLQARVEMLeNEQGQKEAqllgERSHFEEEKQQLASLITNLQSSISNLSQAKeeL 514
Cdd:NF012221  1528 GYILDNVVATSESSQQADAVSKHAKQDDAAQNAL-ADKERAEA----DRQRLEQEKQQQLAAISGSQSQLESTDQNA--L 1600

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  515 EQASQAQGAKLNAQVASLTAELTTLSATL-----QQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSL 589
Cdd:NF012221  1601 ETNGQAQRDAILEESRAVTKELTTLAQGLdaldsQATYAGESGDQWRNPFAGGLLDRVQEQLDDAKKISGKQLADAKQRH 1680

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  590 KQKEKQLEEAARELDA--SRRDHAQQLATAAKAQ---ETSLRERDAACQQLEALEKEKAAKLEILQQQlQAANEAQDSAQ 664
Cdd:NF012221  1681 VDNQQKVKDAVAKSEAgvAQGEQNQANAEQDIDDakaDAEKRKDDALAKQNEAQQAESDANAAANDAQ-SRGEQDASAAE 1759

                          250
                   ....*....|....*.
gi 1196773644  665 NSVTQAQREKAELSQK 680
Cdd:NF012221  1760 NKANQAQADAKGAKQD 1775
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1192-1679 5.61e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 5.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1192 DRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHS-KAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNR 1270
Cdd:COG4913    294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEALLAALGL 373

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1271 QVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQA 1350
Cdd:COG4913    374 PLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEAL 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1351 ERAE----------ELGQELKAWQEKFfqkEQALS--ALQL----EHtstQALVSELLPAKHLCQQLQAEQVaaeKRHRE 1414
Cdd:COG4913    454 GLDEaelpfvgeliEVRPEEERWRGAI---ERVLGgfALTLlvppEH---YAAALRWVNRLHLRGRLVYERV---RTGLP 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1415 ELEQSKQAAGGLRTEL--------MRAQRELGELVPLRqKVAeqerAAQQLRAEKASYAEQlSMLKKAHGLLA-EENRGL 1485
Cdd:COG4913    525 DPERPRLDPDSLAGKLdfkphpfrAWLEAELGRRFDYV-CVD----SPEELRRHPRAITRA-GQVKGNGTRHEkDDRRRI 598

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1486 GERANLG------RQFLEVELDQAREKY------IQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKyegakvkvlEE 1553
Cdd:COG4913    599 RSRYVLGfdnrakLAALEAELAELEEELaeaeerLEALEAELDALQERREALQRLAEYSWDEIDVASAE---------RE 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1554 RQRFQEERQKLTA---QVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQ 1630
Cdd:COG4913    670 IAELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1196773644 1631 mekaktHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQA 1679
Cdd:COG4913    750 ------LLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1255-1713 7.67e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.08  E-value: 7.67e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1255 GSLISSLEEEVSILNR--QVLEKEGESKELKRLVIAESEKSQKLEERLRLLQ-METASNSARAAERSSALREEVQSLREE 1331
Cdd:COG4913    224 FEAADALVEHFDDLERahEALEDAREQIELLEPIRELAERYAAARERLAELEyLRAALRLWFAQRRLELLEAELEELRAE 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1332 VEKQRAASENLRQELASQAERAEEL--------GQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqQLQA 1403
Cdd:COG4913    304 LARLEAELERLEARLDALREELDELeaqirgngGDRLEQLEREIERLERELEERERRRARLEALLAAL--------GLPL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1404 EQVAAE-KRHREELEQSKQAAGGLRTELMRAQRElgelvpLRQKVAEQERAAQQLRAEKAS-----------YAEQLSML 1471
Cdd:COG4913    376 PASAEEfAALRAEAAALLEALEEELEALEEALAE------AEAALRDLRRELRELEAEIASlerrksniparLLALRDAL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1472 KKAHGLLAEENRGLGEranlgrqFLEVELDQAR-----EKYI-----------QELAAVR-----------------GDA 1518
Cdd:COG4913    450 AEALGLDEAELPFVGE-------LIEVRPEEERwrgaiERVLggfaltllvppEHYAAALrwvnrlhlrgrlvyervRTG 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1519 ETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEER---------QRFQEERQKLTA--QVEElSKKLADYDQASKVQQQ 1587
Cdd:COG4913    523 LPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRfdyvcvdspEELRRHPRAITRagQVKG-NGTRHEKDDRRRIRSR 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1588 ---------KLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYK---------VQMEKAKTHYDAKKQQNQELQ 1649
Cdd:COG4913    602 yvlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeyswdeIDVASAEREIAELEAELERLD 681

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1196773644 1650 EQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRE 1713
Cdd:COG4913    682 ASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 341-1017 9.83e-09

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 60.75  E-value: 9.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  341 KINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEKELSTALQDKKCLEEKneiLQGKLSQLE 420
Cdd:TIGR00618  177 QYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAY---LTQKREAQE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  421 ERLaqlpeSPRQEKGEVLGdvlQLESLKQEAATLATNNTQLqarvemlenEQGQKEAQLLGERSHFEEEKQQLASLITNL 500
Cdd:TIGR00618  254 EQL-----KKQQLLKQLRA---RIEELRAQEAVLEETQERI---------NRARKAAPLAAHIKAVTQIEQQAQRIHTEL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  501 QSSISNLSQAKEElEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQglrH 580
Cdd:TIGR00618  317 QSKMRSRAKLLMK-RAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTL---T 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  581 QVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLAtAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQ 660
Cdd:TIGR00618  393 QKLQSLCKELDILQREQATIDTRTSAFRDLQGQLA-HAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKER 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  661 dsaqnsvTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESL 740
Cdd:TIGR00618  472 -------EQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSE 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  741 KITKGSLEEEKCRAAAALEEHQHHISEMEA------------------------ESRSLAEQHKQERKELEEEKAKRRGL 796
Cdd:TIGR00618  545 EDVYHQLTSERKQRASLKEQMQEIQQSFSIltqcdnrskedipnlqnitvrlqdLTEKLSEAEDMLACEQHALLRKLQPE 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  797 GVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQY--GLQEQLTTLKEEYEKSCQ 874
Cdd:TIGR00618  625 QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKmqSEKEQLTYWKEMLAQCQT 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  875 ELRETKEKMAGIEAHSELQIGQHQSELAQLHANLArALQQVQEKENRAQKLADDLSTLQEKmaatSKEVARLEALVRKAG 954
Cdd:TIGR00618  705 LLRELETHIEEYDREFNEIENASSSLGSDLAARED-ALNQSLKELMHQARTVLKARTEAHF----NNNEEVTAALQTGAE 779

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1196773644  955 EQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRA----MEREAEQMGTELEKLRAALME 1017
Cdd:TIGR00618  780 LSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLqcetLVQEEEQFLSRLEEKSATLGE 846
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
858-1436 1.19e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.70  E-value: 1.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  858 LQEQLTTLKEEYEKScQELRETKEKMAGIEAHSElQIGQHQSELAQL-----HANLARALQQVQEKENRAQKLADDLSTL 932
Cdd:COG4913    230 LVEHFDDLERAHEAL-EDAREQIELLEPIRELAE-RYAAARERLAELeylraALRLWFAQRRLELLEAELEELRAELARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  933 QEKMAATSKEVARLEALVRKAGEQQETASLELLkeppktrdresewveEQQGQQLCSTQAALRAMEREAEQMGTELEKLR 1012
Cdd:COG4913    308 EAELERLEARLDALREELDELEAQIRGNGGDRL---------------EQLEREIERLERELEERERRRARLEALLAALG 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1013 AALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQ----------AEFANLQEALSRA 1082
Cdd:COG4913    373 LPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAslerrksnipARLLALRDALAEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1083 LSEKEGkdqELSKLCEqeavqrmelkeLLQtveqlkaqLAKKEKEQQQSARGASGENASGM----GTQSEAVGKMEALR- 1157
Cdd:COG4913    453 LGLDEA---ELPFVGE-----------LIE--------VRPEEERWRGAIERVLGGFALTLlvppEHYAAALRWVNRLHl 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1158 ------AKVSKLEQQCQQQQEEADSLARSLESERafHVERDRALETLQGQLE----EKAREL-GYSQAASASAQRELATL 1226
Cdd:COG4913    511 rgrlvyERVRTGLPDPERPRLDPDSLAGKLDFKP--HPFRAWLEAELGRRFDyvcvDSPEELrRHPRAITRAGQVKGNGT 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1227 RAKAQDHSKAEEEW------KAQVARGQQEAVRkgslissLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERL 1300
Cdd:COG4913    589 RHEKDDRRRIRSRYvlgfdnRAKLAALEAELAE-------LEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1301 RLLQMETASnsARAAERSSALRE---EVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEkffqkEQALSAL 1377
Cdd:COG4913    662 DVASAEREI--AELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEE-----ELDELQD 734

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1196773644 1378 QLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHR--EELEQSKQAAGGLRTELMRAQRE 1436
Cdd:COG4913    735 RLEAAEDLARLELRALLEERFAAALGDAVERELRENleERIDALRARLNRAEEELERAMRA 795
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
234-860 1.43e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.08  E-value: 1.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  234 MGDILQTPQFQMRRLKKQLADERNNRDELElelaEHRKLLTEKDAQISMMQQRIDRLAllnEKQAASPLEPRELEELRGK 313
Cdd:PRK03918   167 LGEVIKEIKRRIERLEKFIKRTENIEELIK----EKEKELEEVLREINEISSELPELR---EELEKLEKEVKELEELKEE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  314 NESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREfasnLQQLQGaLNELTEEHSKATQQWVEKQAHLEK 393
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE----LKELKE-KAEEYIKLSEFYEEYLDELREIEK 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  394 ELSTALQDKKCLEEKNEILQGKLSQLEErLAQLPESPRQEKGEVLGDVLQLESLKQeaatLATNNTQLQARVEMLENEQG 473
Cdd:PRK03918   315 RLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHELYEEAKA----KKEELERLKKRLTGLTPEKL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  474 QKEAQLLGER-SHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQ---AQGAKLNAQ-----VASLTAELTTLSATLQ 544
Cdd:PRK03918   390 EKELEELEKAkEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpVCGRELTEEhrkelLEEYTAELKRIEKELK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  545 QQDQELaglkqqaqkkqaqlaqslqqqeqasqglrhqvEQLSGSLKQKEKQLEEaARELDASRRDHAQQLATAAKAQETS 624
Cdd:PRK03918   470 EIEEKE--------------------------------RKLRKELRELEKVLKK-ESELIKLKELAEQLKELEEKLKKYN 516

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  625 LRERDAACQQLEALeKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEaqtqvaA 704
Cdd:PRK03918   517 LEELEKKAEEYEKL-KEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVE------E 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  705 LEARLKAEQ---QKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcraaAALEEHQHHISEMeaESRSLAEQHKQ 781
Cdd:PRK03918   590 LEERLKELEpfyNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETE----KRLEELRKELEEL--EKKYSEEEYEE 663

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  782 ERKELEEEKAKRRGLGVQLQQLaETHQAETKALRQELAKARTSNNMAEREVELLVK---EVKTWRKRYEDSQQGETQYGL 858
Cdd:PRK03918   664 LREEYLELSRELAGLRAELEEL-EKRREEIKKTLEKLKEELEEREKAKKELEKLEKaleRVEELREKVKKYKALLKERAL 742


                   ..
gi 1196773644  859 QE 860
Cdd:PRK03918   743 SK 744
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1279-1614 1.58e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 60.35  E-value: 1.58e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1279 SKELKRLVIAESEKSQKLE---ERLRLLQmetasNSARAAERSSALREEVQSLREEVEKQ---RAASENLRQELASQAER 1352
Cdd:COG3096    312 ARELEELSARESDLEQDYQaasDHLNLVQ-----TALRQQEKIERYQEDLEELTERLEEQeevVEEAAEQLAEAEARLEA 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1353 AEELGQELKAwQEKFFQkeQALSALQLEHTSTQALVSELLPAKHLCQ--QLQAEQVAA-EKRHREELEQSKQAAGGLRTE 1429
Cdd:COG3096    387 AEEEVDSLKS-QLADYQ--QALDVQQTRAIQYQQAVQALEKARALCGlpDLTPENAEDyLAAFRAKEQQATEEVLELEQK 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1430 LMRAQ---RELGELVPLRQKVA---EQERAAQQLRAEKASYAEQLSMLKKAHGL---LAEENRGLGERANLGRQFLEVEL 1500
Cdd:COG3096    464 LSVADaarRQFEKAYELVCKIAgevERSQAWQTARELLRRYRSQQALAQRLQQLraqLAELEQRLRQQQNAERLLEEFCQ 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1501 DQAR--------EKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQrFQEERQKLTAQVEELS 1572
Cdd:COG3096    544 RIGQqldaaeelEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLA-AQDALERLREQSGEAL 622

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1196773644 1573 KKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQ 1614
Cdd:COG3096    623 ADSQEVTAAMQQLLEREREATVERDELAARKQALESQIERLS 664
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
815-1366 1.60e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.60e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  815 RQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEE---YEKSCQELRETKEKMAG-IEAHS 890
Cdd:PRK02224   168 RERASDARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEierYEEQREQARETRDEADEvLEEHE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  891 ElqigqHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEkmAATSKEVARLEALVRKAGEQQETASLELLKEPPK 970
Cdd:PRK02224   248 E-----RREELETLEAEIEDLRETIAETEREREELAEEVRDLRE--RLEELEEERDDLLAEAGLDDADAEAVEARREELE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  971 TRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRaalmesqgqqqeergqqeREVARLTQERGQAEADLALE 1050
Cdd:PRK02224   321 DRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELR------------------EEAAELESELEEAREAVEDR 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1051 KAAKAELEMRLQnalnEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQL-AKKEKEQQ 1129
Cdd:PRK02224   383 REEIEELEEEIE----ELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLeAGKCPECG 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1130 QSARGAsgENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLArslESERAFHVERDRAlETLQGQLEEKarel 1209
Cdd:PRK02224   459 QPVEGS--PHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLV---EAEDRIERLEERR-EDLEELIAER---- 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1210 gysqAASASAQRE-LATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEvsilnRQVLEKEGESKELKRLVIA 1288
Cdd:PRK02224   529 ----RETIEEKRErAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK-----LAELKERIESLERIRTLLA 599

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1196773644 1289 ESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAasENLRQELASQAERAEELGQELKAWQEK 1366
Cdd:PRK02224   600 AIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARI--EEAREDKERAEEYLEQVEEKLDELREE 675
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
596-1014 2.19e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 2.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  596 LEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQ---LQAANEAQDSAQNSVTQAQR 672
Cdd:PRK02224   277 LAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECrvaAQAHNEEAESLREDADDLEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  673 EKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQK-----------ATEREKVAQEKAQLQEQLWSLEESLK 741
Cdd:PRK02224   357 RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdapvdlgnaEDFLEELREERDELREREAELEATLR 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  742 ITKGSLEEE-------KCRAAAALEEHQHHISEMEaESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAEthqaetkal 814
Cdd:PRK02224   437 TARERVEEAealleagKCPECGQPVEGSPHVETIE-EDRERVEELEAELEDLEEEVEEVEERLERAEDLVE--------- 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  815 rqelakartsnnmAEREVELLVKEVKTWRKRYEDsqQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAgiEAHSELQi 894
Cdd:PRK02224   507 -------------AEDRIERLEERREDLEELIAE--RRETIEEKRERAEELRERAAELEAEAEEKREAAA--EAEEEAE- 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  895 gqhqsELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETaslelLKEppkTRDR 974
Cdd:PRK02224   569 -----EAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRER-----LAE---KRER 635

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1196773644  975 ESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAA 1014
Cdd:PRK02224   636 KRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREE 675
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1039-1585 2.38e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 2.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1039 ERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQ---ELSKLCEQEAVQRMELKELLQTVE 1115
Cdd:PRK02224   182 LSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQAREtrdEADEVLEEHEERREELETLEAEIE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1116 QLKAQLAKKEKEQqqsargasgenasgmgtqseavgkmEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRAL 1195
Cdd:PRK02224   262 DLRETIAETERER-------------------------EELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARR 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1196 ETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEK 1275
Cdd:PRK02224   317 EELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1276 EgeskelKRLVIAESEKsQKLEERLRLLqmetASNSARAAERSSALREEVQSLREEVEKQRAASENLR------------ 1343
Cdd:PRK02224   397 R------ERFGDAPVDL-GNAEDFLEEL----REERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsp 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1344 --QELASQAERAEELGQELKAWQEKFFQKEQALSALQlEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQ 1421
Cdd:PRK02224   466 hvETIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRE 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1422 AAGGLRTEL-----------MRAQRELGELVPLRQKVAEQERAAQQLR------AEKASYAEQLSMLKKAHGLLAEENR- 1483
Cdd:PRK02224   545 RAAELEAEAeekreaaaeaeEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDEIERLREKREALAELNDe 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1484 ---GLGERANLGRQfLEVELDQARekyIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKvLEERQRFQEE 1560
Cdd:PRK02224   625 rreRLAEKRERKRE-LEAEFDEAR---IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENE-LEELEELRER 699

                          570       580
                   ....*....|....*....|....*
gi 1196773644 1561 RQKLTAQVEELSkklADYDQASKVQ 1585
Cdd:PRK02224   700 REALENRVEALE---ALYDEAEELE 721
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 256-1071 2.64e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 59.58  E-value: 2.64e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  256 RNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLAllnekqaasplepRELEELRGKNESLTFRLHETLKQCQDLKTEK 335
Cdd:COG3096    277 ANERRELSERALELRRELFGARRQLAEEQYRLVEMA-------------RELEELSARESDLEQDYQAASDHLNLVQTAL 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  336 GQMDrKINQLSEENGDLSFKLREfasnlqqLQGALNELTEEHSKATQQWVEKQAHLeKELSTALQDkkcLEEKNEILQGK 415
Cdd:COG3096    344 RQQE-KIERYQEDLEELTERLEE-------QEEVVEEAAEQLAEAEARLEAAEEEV-DSLKSQLAD---YQQALDVQQTR 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  416 LSQLEERLAQLpesprqEKGEVLgdvLQLESLKQEAA--TLATNNTQLQARVE-MLENEQGQKEAQllGERSHFEEEKQQ 492
Cdd:COG3096    412 AIQYQQAVQAL------EKARAL---CGLPDLTPENAedYLAAFRAKEQQATEeVLELEQKLSVAD--AARRQFEKAYEL 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  493 LASLITNLQSSISNlSQAKEELEQASQAQgaKLNAQVASLTAELTTLSATLQQQDQelaglkqqaqkkqaqlaqslqqqe 572
Cdd:COG3096    481 VCKIAGEVERSQAW-QTARELLRRYRSQQ--ALAQRLQQLRAQLAELEQRLRQQQN------------------------ 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  573 qasqgLRHQVEQLSGSLKQK---EKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEK------EKA 643
Cdd:COG3096    534 -----AERLLEEFCQRIGQQldaAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAArapawlAAQ 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  644 AKLEILQQQ----LQAANEAQDSAQNSV---TQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQ--- 713
Cdd:COG3096    609 DALERLREQsgeaLADSQEVTAAMQQLLereREATVERDELAARKQALESQIERLSQPGGAEDPRLLALAERLGGVLlse 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  714 -------QKATEREK---------VAQEKAQLQEQLWSLE---ESLKITKG----------SLEEEKCRAAAALEEHQHH 764
Cdd:COG3096    689 iyddvtlEDAPYFSAlygparhaiVVPDLSAVKEQLAGLEdcpEDLYLIEGdpdsfddsvfDAEELEDAVVVKLSDRQWR 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  765 ISEMEA---------ESRslAEQHKQERKELEEEKAKRRglgVQLQQLAETHQAETKALRQ------------ELAKART 823
Cdd:COG3096    769 YSRFPEvplfgraarEKR--LEELRAERDELAEQYAKAS---FDVQKLQRLHQAFSQFVGGhlavafapdpeaELAALRQ 843

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  824 SNNMAEREVELLVKEVKTWRKRYEDSQQGETQY-GLQEQLTTLKEE-YEKSCQELREtkEKMAGIEAHSELQigQHQSEL 901
Cdd:COG3096    844 RRSELERELAQHRAQEQQLRQQLDQLKEQLQLLnKLLPQANLLADEtLADRLEELRE--ELDAAQEAQAFIQ--QHGKAL 919

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  902 AQLhANLARALQ----QVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLEL-------LKEPPK 970
Cdd:COG3096    920 AQL-EPLVAVLQsdpeQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGENSDLneklrarLEQAEE 998

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  971 TRDRESEWVEEQQGQ--QLCSTQAALRAMEREAEQMGTELEKLRAAL-----MESQGQQQEERGQQEREVARLTQERGQA 1043
Cdd:COG3096    999 ARREAREQLRQAQAQysQYNQVLASLKSSRDAKQQTLQELEQELEELgvqadAEAEERARIRRDELHEELSQNRSRRSQL 1078

                          890       900
                   ....*....|....*....|....*...
gi 1196773644 1044 EADLALEKAAKAELEMRLQNALNEQQAE 1071
Cdd:COG3096   1079 EKQLTRCEAEMDSLQKRLRKAERDYKQE 1106
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
460-955 2.75e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 59.01  E-value: 2.75e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  460 QLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQAsQAQGAKLNAQVASLTA--ELT 537
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEEL-EAELEELREELEKLEKllQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  538 TLSATLQQQDQELAGLKQQAQKKQAQLAQSLQqqeqasqgLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATA 617
Cdd:COG4717    129 PLYQELEALEAELAELPERLEELEERLEELRE--------LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  618 AKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQ----AQREKAELSQKVEELHALIEAAHQ 693
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLliaaALLALLGLGGSLLSLILTIAGVLF 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  694 EQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWsleESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESR 773
Cdd:COG4717    281 LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEEL---EELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  774 SLAEQHKQERKELEeekakrrglgvqLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGE 853
Cdd:COG4717    358 ELEEELQLEELEQE------------IAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  854 TQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAhsELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQ 933
Cdd:COG4717    426 DEEELEEELEELEEELEELEEELEELREELAELEA--ELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLE 503

                          490       500
                   ....*....|....*....|..
gi 1196773644  934 EKMAATSKEvaRLEALVRKAGE 955
Cdd:COG4717    504 EAREEYREE--RLPPVLERASE 523
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
355-824 3.45e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 3.45e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  355 KLREFASNLQQLQGALNELTEEHSKATQQWVE-KQAHLE---KELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESP 430
Cdd:COG4913    296 ELEELRAELARLEAELERLEARLDALREELDElEAQIRGnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPL 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  431 RQEKGEvlgdvlqLESLKQEAATLATNNTQLQARVEmleneqgQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLS-- 508
Cdd:COG4913    376 PASAEE-------FAALRAEAAALLEALEEELEALE-------EALAEAEAALRDLRRELRELEAEIASLERRKSNIPar 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  509 --QAKEELEQASQAQGAKLNA-----QVASLTAE--------LTTLSATL---QQQDQELAGLKQQAQKKQAQLAQSLQQ 570
Cdd:COG4913    442 llALRDALAEALGLDEAELPFvgeliEVRPEEERwrgaiervLGGFALTLlvpPEHYAAALRWVNRLHLRGRLVYERVRT 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  571 QEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHA-----QQLATAAKA--------QETSLRERDAACQQLEA 637
Cdd:COG4913    522 GLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRFDYVcvdspEELRRHPRAitragqvkGNGTRHEKDDRRRIRSR 601

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  638 --LEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQ--CEAQTQVAALEARLKAEQ 713
Cdd:COG4913    602 yvLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLD 681

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  714 QKATEREKVAQEKAQLQEQLWSLEE---SLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEK 790
Cdd:COG4913    682 ASSDDLAALEEQLEELEAELEELEEeldELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD 761

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1196773644  791 AKRRGLGVQLQQLAETHQAETKALRQELAKARTS 824
Cdd:COG4913    762 AVERELRENLEERIDALRARLNRAEEELERAMRA 795
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1067-1587 3.70e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.92  E-value: 3.70e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1067 EQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQ 1146
Cdd:PRK03918   186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1147 S---EAVGKMEALRAKVSKLEQQCQQQQEEadslaRSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQREL 1223
Cdd:PRK03918   266 ErieELKKEIEELEEKVKELKELKEKAEEY-----IKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1224 ATLRAKAQDHSKAEEEWKAQVaRGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKsqKLEERLRLL 1303
Cdd:PRK03918   341 EELKKKLKELEKRLEELEERH-ELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEIS--KITARIGEL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1304 -----QMETASNSARAAERSSAL--REEVQSLREEV-EKQRAASENLRQELASQAERAEELGQELKAWqEKFFQKEQALS 1375
Cdd:PRK03918   418 kkeikELKKAIEELKKAKGKCPVcgRELTEEHRKELlEEYTAELKRIEKELKEIEEKERKLRKELREL-EKVLKKESELI 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1376 ALQlehtstqALVSELLPAKHLCQQLQAEQVAAEKrhrEELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQ 1455
Cdd:PRK03918   497 KLK-------ELAEQLKELEEKLKKYNLEELEKKA---EEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLD 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1456 QLRAEKASYAEQLSmlKKAHGLLAEENRGLGERANLGRQFLEVeldQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHE 1535
Cdd:PRK03918   567 ELEEELAELLKELE--ELGFESVEELEERLKELEPFYNEYLEL---KDAEKELEREEKELKKLEEELDKAFEELAETEKR 641

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1196773644 1536 LEVMTAKYEGAKVKVLEErqRFQEERQKLTAQVEELSKKLADYDQASKVQQQ 1587
Cdd:PRK03918   642 LEELRKELEELEKKYSEE--EYEELREEYLELSRELAGLRAELEELEKRREE 691
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
489-1014 5.35e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.39  E-value: 5.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  489 EKQQLASLITNLQSSISNLSQAKEELEQAsQAQGAKLnAQVASLTAELTTLSATLQQQDQELAGlkqqaqkkqaqlaqsl 568
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALEDA-REQIELL-EPIRELAERYAAARERLAELEYLRAA---------------- 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  569 qqqeqasqgLRHQVEQLS-GSLKQKEKQLEEAARELDASRRDHAQQLaTAAKAQETSLRE--RDAACQQLEALEKEKAAK 645
Cdd:COG4913    281 ---------LRLWFAQRRlELLEAELEELRAELARLEAELERLEARL-DALREELDELEAqiRGNGGDRLEQLEREIERL 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  646 LEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQkatEREKVAQE 725
Cdd:COG4913    351 ERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRR---ELRELEAE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  726 KAQLQEQLWS-----------LEESLKITKGSL-----------EEEKCRAAA--------------------------- 756
Cdd:COG4913    428 IASLERRKSNiparllalrdaLAEALGLDEAELpfvgelievrpEEERWRGAIervlggfaltllvppehyaaalrwvnr 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  757 ----------ALEEHQHHISEMEAESRSLAEQ---------------------------------------------HKQ 781
Cdd:COG4913    508 lhlrgrlvyeRVRTGLPDPERPRLDPDSLAGKldfkphpfrawleaelgrrfdyvcvdspeelrrhpraitragqvkGNG 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  782 ERKELEEEKAKRRG--LGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQ 859
Cdd:COG4913    588 TRHEKDDRRRIRSRyvLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAE 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  860 EQLTTLKEEYEkscqELRETkekmagieahselqigqhQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAAT 939
Cdd:COG4913    668 REIAELEAELE----RLDAS------------------SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQA 725

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644  940 SKEVARLEALVRKAGEQQETASLELLKEppktrDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAA 1014
Cdd:COG4913    726 EEELDELQDRLEAAEDLARLELRALLEE-----RFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 271-887 5.74e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.21  E-value: 5.74e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  271 KLLTEKDAQISMMQQRIdrlallnekqaaSPLEPrELEELRGKNESltfRLHETLKQCQDlktekgQMDRKINQLSEENG 350
Cdd:pfam15921  224 KILRELDTEISYLKGRI------------FPVED-QLEALKSESQN---KIELLLQQHQD------RIEQLISEHEVEIT 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  351 DLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEkelSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESP 430
Cdd:pfam15921  282 GLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLE---STVSQLRSELREAKRMYEDKIEELEKQLVLANSEL 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  431 RQEKGEvlgdvlqLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQ-----------------LLGERSHFEEEKQQL 493
Cdd:pfam15921  359 TEARTE-------RDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhLRRELDDRNMEVQRL 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  494 ASLITNLQSSisnlSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQlaqslqqqeq 573
Cdd:pfam15921  432 EALLKAMKSE----CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT---------- 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  574 asqglrhqVEQLSGSLKQKEKQLEEAARELDA--SRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQ 651
Cdd:pfam15921  498 --------VSDLTASLQEKERAIEATNAEITKlrSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQ 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  652 QLQAANEAQDSAQNSVTQAQREKAELSQKV-------EELHALIEAAHQEQCEAQTQVAALE-----------ARLKAEQ 713
Cdd:pfam15921  570 QIENMTQLVGQHGRTAGAMQVEKAQLEKEIndrrlelQEFKILKDKKDAKIRELEARVSDLElekvklvnagsERLRAVK 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  714 QKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcraaaaleehqhhiSEMEAESRSLAEQHKQERKELEEEKAKR 793
Cdd:pfam15921  650 DIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKS--------------EEMETTTNKLKMQLKSAQSELEQTRNTL 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  794 RGLgvqlqQLAETHQAETK-ALRQELAKARTSNNMAEREVELLVKEVKTWRKryEDSQQGETQYGLQEQLTTLKEEYEKS 872
Cdd:pfam15921  716 KSM-----EGSDGHAMKVAmGMQKQITAKRGQIDALQSKIQFLEEAMTNANK--EKHFLKEEKNKLSQELSTVATEKNKM 788

                          650       660
                   ....*....|....*....|..
gi 1196773644  873 CQEL-------RETKEKMAGIE 887
Cdd:pfam15921  789 AGELevlrsqeRRLKEKVANME 810
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1399-1704 9.70e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.77  E-value: 9.70e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1399 QQLQAEQVAAEKRH--REELEQSKQAAGGLRTELMRAQRE--LGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKA 1474
Cdd:TIGR02169  201 ERLRREREKAERYQalLKEKREYEGYELLKEKEALERQKEaiERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKK 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1475 hgllaEENRGLGERANLGRQFLEVELDQAREKYIQELAAVR-GDAETRLA---EMRQEVQSTTHELEVMTAKYEGAKVKV 1550
Cdd:TIGR02169  281 -----IKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERElEDAEERLAkleAEIDKLLAEIEELEREIEEERKRRDKL 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1551 LEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQ 1630
Cdd:TIGR02169  356 TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAK 435

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1196773644 1631 MEKAKThydAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQV 1704
Cdd:TIGR02169  436 INELEE---EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERV 506
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 356-1115 1.58e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.05  E-value: 1.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  356 LREFASNLQQLQGALNELTEEHSKatQQWVEKQAHLekELSTALQDKkcleeknEILQGKLSQLEERLAQLPESPRQEKG 435
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELHEK--QKFYLRQSVI--DLQTKLQEM-------QMERDAMADIRRRESQSQEDLRNQLQ 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  436 EVLGDVLQLESLKQEaaTLATNNTQLQARVEMLENEQG-------------QKEAQLLGERS-----HFEEEKQQLASLI 497
Cdd:pfam15921  149 NTVHELEAAKCLKED--MLEDSNTQIEQLRKMMLSHEGvlqeirsilvdfeEASGKKIYEHDsmstmHFRSLGSAISKIL 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  498 TNLQSSISNL---------------SQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQA 562
Cdd:pfam15921  227 RELDTEISYLkgrifpvedqlealkSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  563 QLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEAL---- 638
Cdd:pfam15921  307 QARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLladl 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  639 -EKEKAAKLEILQQQLQAANEAQDSAqnSVTQAQREKAELSQKVEELHALIEAAHQEqCEAQtqvaaLEARLKAEQQKAT 717
Cdd:pfam15921  387 hKREKELSLEKEQNKRLWDRDTGNSI--TIDHLRRELDDRNMEVQRLEALLKAMKSE-CQGQ-----MERQMAAIQGKNE 458

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  718 EREKVAQEKAQLQ---EQLWSLEESLKITKGSLEEEKCRAA---AALEEHQHHISEMEAESRSLAEQHKQERKELEEEKA 791
Cdd:pfam15921  459 SLEKVSSLTAQLEstkEMLRKVVEELTAKKMTLESSERTVSdltASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKN 538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  792 KrrglGVQLQQLaethQAETKALRQELAKARTSNNMAEREVELLVKEVktwrkryedSQQGETQYGLQEQLTTLKEEYEK 871
Cdd:pfam15921  539 E----GDHLRNV----QTECEALKLQMAEKDKVIEILRQQIENMTQLV---------GQHGRTAGAMQVEKAQLEKEIND 601

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  872 SCQELRE---TKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEA 948
Cdd:pfam15921  602 RRLELQEfkiLKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR 681

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  949 LVRKAGEQQETASLEL---LKEPPKTRDRESEWVEEQQGQQLCSTQAALrAMEREAEQMGTELEKLRAA---LMESQGQQ 1022
Cdd:pfam15921  682 NFRNKSEEMETTTNKLkmqLKSAQSELEQTRNTLKSMEGSDGHAMKVAM-GMQKQITAKRGQIDALQSKiqfLEEAMTNA 760

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1023 QEERGQQEREVARLTQERgqaeADLALEKAAKA-ELEMrLQNALNEQQAEFANLQEALSRAlSEKEGKDQELSKLCEQEA 1101
Cdd:pfam15921  761 NKEKHFLKEEKNKLSQEL----STVATEKNKMAgELEV-LRSQERRLKEKVANMEVALDKA-SLQFAECQDIIQRQEQES 834

                          810
                   ....*....|....
gi 1196773644 1102 VqRMELKELLQTVE 1115
Cdd:pfam15921  835 V-RLKLQHTLDVKE 847
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 640-1634 1.62e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 56.72  E-value: 1.62e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  640 KEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQvaaLEARLKAEQQKATEr 719
Cdd:pfam01576   18 KERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHE---LESRLEEEEERSQQ- 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  720 ekVAQEKAQLQEQLWSLEESLKITKGS---LEEEKCRAAAALEEHQHHISEMEAESRSLaeqhKQERKELEEEKAKrrgl 796
Cdd:pfam01576   94 --LQNEKKKMQQHIQDLEEQLDEEEAArqkLQLEKVTTEAKIKKLEEDILLLEDQNSKL----SKERKLLEERISE---- 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  797 gvqlqqlAETHQAETKALRQELAKARTSNNMAEREVEL-LVKEVKTWRKRYEDSQQGETQYG-LQEQLTTLKEEYEKSCQ 874
Cdd:pfam01576  164 -------FTSNLAEEEEKAKSLSKLKNKHEAMISDLEErLKKEEKGRQELEKAKRKLEGESTdLQEQIAELQAQIAELRA 236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  875 ELRETKEKMAGIEAHSELQIGQH----------QSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVA 944
Cdd:pfam01576  237 QLAKKEEELQAALARLEEETAQKnnalkkirelEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTA 316

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  945 RLEALvRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLCSTQAALRamerEAEQMGTELEKLRAALMESQGQQQE 1024
Cdd:pfam01576  317 AQQEL-RSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLE----QAKRNKANLEKAKQALESENAELQA 391

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1025 ERGQQEREVARLTQERGQAEADLAlEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQR 1104
Cdd:pfam01576  392 ELRTLQQAKQDSEHKRKKLEGQLQ-ELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQL 470

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1105 MELKELLQTVEQLKAQLAKKekeqqqsARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESE 1184
Cdd:pfam01576  471 QDTQELLQEETRQKLNLSTR-------LRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAL 543

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1185 RAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEE 1264
Cdd:pfam01576  544 EEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEE 623

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1265 VSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMET---------ASNSARAAERSS-ALREEVQSLR---EE 1331
Cdd:pfam01576  624 RDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMedlvsskddVGKNVHELERSKrALEQQVEEMKtqlEE 703

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1332 VEKQRAASEN--LRQELASQAERAEeLGQELKAWQEKFFQKEQALSA--------LQLEHTSTQALVSELLPAKHLCQQL 1401
Cdd:pfam01576  704 LEDELQATEDakLRLEVNMQALKAQ-FERDLQARDEQGEEKRRQLVKqvreleaeLEDERKQRAQAVAAKKKLELDLKEL 782

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1402 QAEQVAAEKRHREELEQSKQaaggLRTELMRAQRELGELVPLRQKV----AEQERAAQQLRAEKASYAEQLSMLKKAHGL 1477
Cdd:pfam01576  783 EAQIDAANKGREEAVKQLKK----LQAQMKDLQRELEEARASRDEIlaqsKESEKKLKNLEAELLQLQEDLAASERARRQ 858

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1478 LAEENRGLGERANLGRQFLEVELDQAREkyiqeLAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEER--- 1554
Cdd:pfam01576  859 AQQERDELADEIASGASGKSALQDEKRR-----LEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERsts 933

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1555 QRFQEERQKLTAQVEELSKKLADYDQASKVQQQ--------KLKAFQAQGGESQQEAQ-------RLQTQLNELQVQLSQ 1619
Cdd:pfam01576  934 QKSESARQQLERQNKELKAKLQEMEGTVKSKFKssiaaleaKIAQLEEQLEQESRERQaanklvrRTEKKLKEVLLQVED 1013

                         1050
                   ....*....|....*
gi 1196773644 1620 KEQAAEHYKVQMEKA 1634
Cdd:pfam01576 1014 ERRHADQYKDQAEKG 1028
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1193-1624 1.71e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.31  E-value: 1.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1193 RALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVrkgslISSLEEEVSILNRQV 1272
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAE-----LAELPERLEELEERL 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1273 LEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAER 1352
Cdd:COG4717    156 EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1353 AEELGQELKAWQEKFFQKEQA-LSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELM 1431
Cdd:COG4717    236 LEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEE 315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1432 RAQRELGELVplrqkvaeqERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRglgeranLGRQFLEVELDQAREKYIQEL 1511
Cdd:COG4717    316 LEEEELEELL---------AALGLPPDLSPEELLELLDRIEELQELLREAEE-------LEEELQLEELEQEIAALLAEA 379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1512 AAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERqkLTAQVEELSKKLADYDQASKVQQQKLKA 1591
Cdd:COG4717    380 GVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE--LEEELEELEEELEELEEELEELREELAE 457

                          410       420       430
                   ....*....|....*....|....*....|....*
gi 1196773644 1592 FQAQGG--ESQQEAQRLQTQLNELQVQLSQKEQAA 1624
Cdd:COG4717    458 LEAELEqlEEDGELAELLQELEELKAELRELAEEW 492
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
443-879 1.91e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.46  E-value: 1.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  443 QLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGER-SHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQ 521
Cdd:COG4913    256 PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRGN 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  522 G----AKLNAQVASLTAELTTLSATLQQQDQ-------ELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLK 590
Cdd:COG4913    336 GgdrlEQLEREIERLERELEERERRRARLEAllaalglPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALR 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  591 QKEKQLEEAARELDASRR-----DHAQQLATAAKAQETSLRERDA--ACQQLEALEKEKA-----------AKLEIL--Q 650
Cdd:COG4913    416 DLRRELRELEAEIASLERrksniPARLLALRDALAEALGLDEAELpfVGELIEVRPEEERwrgaiervlggFALTLLvpP 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  651 QQLQAANEAQDS-----------AQNSVTQAQREKAE---LSQKVE-ELHALIEAAHQE--------QCE---------- 697
Cdd:COG4913    496 EHYAAALRWVNRlhlrgrlvyerVRTGLPDPERPRLDpdsLAGKLDfKPHPFRAWLEAElgrrfdyvCVDspeelrrhpr 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  698 --------------------------------AQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKG 745
Cdd:COG4913    576 aitragqvkgngtrhekddrrrirsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE 655

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  746 SLEEEKCRAAAA--LEEHQHHISEMEAES---RSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAK 820
Cdd:COG4913    656 YSWDEIDVASAEreIAELEAELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDR 735

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1196773644  821 ARTSNNMAEREVELLVKEVktWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRET 879
Cdd:COG4913    736 LEAAEDLARLELRALLEER--FAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
305-738 1.93e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.31  E-value: 1.93e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  305 RELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELT--EEHSKATQ 382
Cdd:COG4717     53 KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEklLQLLPLYQ 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  383 QWVEKQAHLE------KELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVL-QLESLKQEAATLA 455
Cdd:COG4717    133 ELEALEAELAelperlEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAeELEELQQRLAELE 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  456 TNNTQLQARVEMLENEQGQKEAQLLG----ERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVAS 531
Cdd:COG4717    213 EELEEAQEELEELEEELEQLENELEAaaleERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLL 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  532 LTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSgSLKQKEKQLEEAARELDASRRDHA 611
Cdd:COG4717    293 LAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE-ELQELLREAEELEEELQLEELEQE 371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  612 QQlATAAKAQETSLRERDAACQQLEALEkEKAAKLEILQQQLQAANEAQDSAqnsvtQAQREKAELSQKVEELHALIEAA 691
Cdd:COG4717    372 IA-ALLAEAGVEDEEELRAALEQAEEYQ-ELKEELEELEEQLEELLGELEEL-----LEALDEEELEEELEELEEELEEL 444

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1196773644  692 HQEQCEAQTQVAALEARLKaEQQKATEREKVAQEKAQLQEQLWSLEE 738
Cdd:COG4717    445 EEELEELREELAELEAELE-QLEEDGELAELLQELEELKAELRELAE 490
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 851-1071 2.10e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 2.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  851 QGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAhselQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLS 930
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLK----QLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  931 TLQEKMAATSKEVARLEALVRKAGEQQETASLeLLKEPPKTRDRESEWVE------EQQGQQLCSTQAALRAMEREAEQM 1004
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPLALL-LSPEDFLDAVRRLQYLKylaparREQAEELRADLAELAALRAELEAE 172

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1196773644 1005 GTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAE 1071
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 643-885 2.11e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 2.11e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  643 AAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKA-EQQKATEREK 721
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAElEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  722 VAQEKAQLQEQLWSLEESLKitkgsleeekcRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLgVQLQ 801
Cdd:COG4942     99 LEAQKEELAELLRALYRLGR-----------QPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL-AALR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  802 QLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQgetqyGLQEQLTTLKEEYEKSCQELRETKE 881
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELA-----ELQQEAEELEALIARLEAEAAAAAE 241


                   ....
gi 1196773644  882 KMAG 885
Cdd:COG4942    242 RTPA 245
PRK11281 PRK11281
mechanosensitive channel MscK;
364-672 2.12e-07

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 56.46  E-value: 2.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  364 QQLQgALN--ELTEEHSKATQQwvekqaHLEKELSTaLQDKKCLEEKNEilqgklsQLEERLAQLPESPRQEKGEvlgdv 441
Cdd:PRK11281    43 AQLD-ALNkqKLLEAEDKLVQQ------DLEQTLAL-LDKIDRQKEETE-------QLKQQLAQAPAKLRQAQAE----- 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  442 lqLESLKQEAATLA------TNNTQLQARVEMLENEQGQKEAQLLGERShfeeekqQLASLIT---NLQSSISNLSQAKE 512
Cdd:PRK11281   103 --LEALKDDNDEETretlstLSLRQLESRLAQTLDQLQNAQNDLAEYNS-------QLVSLQTqpeRAQAALYANSQRLQ 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  513 ELEQ---ASQAQGAKLNA-QVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQasqgLRHQVEQLSGS 588
Cdd:PRK11281   174 QIRNllkGGKVGGKALRPsQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQR----LEHQLQLLQEA 249

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  589 LKQKE-KQLEEAAREldasrrdhAQQLATAAKAQETSLrerdaacqqleaLEKEKAAKLEI---LQQQLQAANE-AQDSA 663
Cdd:PRK11281   250 INSKRlTLSEKTVQE--------AQSQDEAARIQANPL------------VAQELEINLQLsqrLLKATEKLNTlTQQNL 309

                          330
                   ....*....|....
gi 1196773644  664 Q-----NSVTQAQR 672
Cdd:PRK11281   310 RvknwlDRLTQSER 323
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 832-1582 2.30e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 56.52  E-value: 2.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  832 VELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELR-ETKEKMAGIEAHSELQIGQHQSELAQLHANLAR 910
Cdd:TIGR00618  221 KQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRaRIEELRAQEAVLEETQERINRARKAAPLAAHIK 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  911 ALQQVQekenraQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVEEQQGQQLCST 990
Cdd:TIGR00618  301 AVTQIE------QQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQ 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  991 QAALRAMEREAEQMGTELEKLRAAlmesqgqqqeergqqEREVARLTQERGQAEADLALEKAAKAELemrlqnALNEQQA 1070
Cdd:TIGR00618  375 HTLTQHIHTLQQQKTTLTQKLQSL---------------CKELDILQREQATIDTRTSAFRDLQGQL------AHAKKQQ 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1071 EFANLQEALSRALSEKEGKDQELSKLCEQEAVQRM-ELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGtqsea 1149
Cdd:TIGR00618  434 ELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLkEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCG----- 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1150 vgkmealrakvskleqqcqqqqeeadslarsleSERAFHVERDRALETLQGQLEEKARELGYSQAasasaQRELATLRAK 1229
Cdd:TIGR00618  509 ---------------------------------SCIHPNPARQDIDNPGPLTRRMQRGEQTYAQL-----ETSEEDVYHQ 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1230 AQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELkrlviAESEKSQKLEERLRLLQMETAS 1309
Cdd:TIGR00618  551 LTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKL-----SEAEDMLACEQHALLRKLQPEQ 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1310 NSARaaerssaLREEVQSLREEVEKQRAASENLRQELASQAERaEELGQELKAWQEKFFQKEQALSALQLEHTSTqALVS 1389
Cdd:TIGR00618  626 DLQD-------VRLHLQQCSQELALKLTALHALQLTLTQERVR-EHALSIRVLPKELLASRQLALQKMQSEKEQL-TYWK 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1390 ELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGG-LRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQL 1468
Cdd:TIGR00618  697 EMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSdLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQT 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1469 -SMLKKAHGLLAEENRGLGERANLGRQfLEVELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGak 1547
Cdd:TIGR00618  777 gAELSHLAAEIQFFNRLREEDTHLLKT-LEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLK-- 853

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 1196773644 1548 vkvLEERQRFQEERQKLTAQVEELSKKLADYDQAS 1582
Cdd:TIGR00618  854 ---YEECSKQLAQLTQEQAKIIQLSDKLNGINQIK 885
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1184-1714 2.62e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.08  E-value: 2.62e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1184 ERAFHVERDRALETLQGQLEEKARELgysqaasASAQRELATLRAKAQDHSKAEEEWKAQVARgqqeavRKGSLISSLEE 1263
Cdd:COG4913    279 AALRLWFAQRRLELLEAELEELRAEL-------ARLEAELERLEARLDALREELDELEAQIRG------NGGDRLEQLER 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1264 EVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLR 1343
Cdd:COG4913    346 EIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELE 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1344 QELASQAERAEELGQELKAwqekffQKEQALSALQLehtSTQAL--VSELLpakhlcqQLQAE----QVAAEKrhreele 1417
Cdd:COG4913    426 AEIASLERRKSNIPARLLA------LRDALAEALGL---DEAELpfVGELI-------EVRPEeerwRGAIER------- 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1418 qskqAAGGLRTELMRAQRELGEL------VPLR-----QKVAEQERAAQQLRAEKASYAEQLSMlkKAHGLLAEENRGLG 1486
Cdd:COG4913    483 ----VLGGFALTLLVPPEHYAAAlrwvnrLHLRgrlvyERVRTGLPDPERPRLDPDSLAGKLDF--KPHPFRAWLEAELG 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1487 ERANLGRQFLEVELDQAR--------------------EKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGa 1546
Cdd:COG4913    557 RRFDYVCVDSPEELRRHPraitragqvkgngtrhekddRRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEA- 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1547 kvkvLEERQRFQEERQKLTAQVEELSKKLADYDQASKvQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEH 1626
Cdd:COG4913    636 ----LEAELDALQERREALQRLAEYSWDEIDVASAER-EIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDE 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1627 YKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEaERLGQELQQAGLKTKEaeqtcRHLTAQVRSLEAQVAH 1706
Cdd:COG4913    711 LKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE-ERFAAALGDAVERELR-----ENLEERIDALRARLNR 784


                   ....*...
gi 1196773644 1707 ADQQLREL 1714
Cdd:COG4913    785 AEEELERA 792
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1257-1571 3.03e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.90  E-value: 3.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1257 LISSLEEEVSILNRQVLEKeGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQR 1336
Cdd:pfam17380  274 LLHIVQHQKAVSERQQQEK-FEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELER 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1337 AASENLRQELasQAERAEELGQELKAWQEkffqkeqaLSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREEL 1416
Cdd:pfam17380  353 IRQEERKREL--ERIRQEEIAMEISRMRE--------LERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEM 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1417 EQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAaQQLRAEKASYAEQlsmlKKAHGLLAEENRGLGERANLGRQFL 1496
Cdd:pfam17380  423 EQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQ-QQVERLRQQEEER----KRKKLELEKEKRDRKRAEEQRRKIL 497

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1497 EVELDQAREKYIQElaavRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEEL 1571
Cdd:pfam17380  498 EKELEERKQAMIEE----ERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRL 568
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
363-810 3.95e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.16  E-value: 3.95e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  363 LQQLQGALNEL----------TEEHSKATQQWVEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQL------ 426
Cdd:COG4717     48 LERLEKEADELfkpqgrkpelNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLekllql 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  427 ---PESPRQEKGEVLGDVLQLESLKQEAATLAtnntQLQARVEMLENEQGQKEAQLLGERSHF-EEEKQQLASLITNLQS 502
Cdd:COG4717    128 lplYQELEALEAELAELPERLEELEERLEELR----ELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEE 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  503 SISNLSQAKEELEQAsQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQV 582
Cdd:COG4717    204 LQQRLAELEEELEEA-QEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  583 EQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDS 662
Cdd:COG4717    283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  663 AQNSVTQAQREKAELSQKVEELHALIEAA--HQEQCEAQTQVAALEARLkAEQQKATEREKVAQEKAQLQEQLWSLEESL 740
Cdd:COG4717    363 LQLEELEQEIAALLAEAGVEDEEELRAALeqAEEYQELKEELEELEEQL-EELLGELEELLEALDEEELEEELEELEEEL 441

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644  741 KitkgSLEEEKCRAAAALEEHQHHISEME-----AESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAE 810
Cdd:COG4717    442 E----ELEEELEELREELAELEAELEQLEedgelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
244-750 4.06e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 4.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  244 QMRRLKKQLADERNNRDELELELAEHRklltEKDAQISMMQQRIDRLallNEKQAASPlepRELEELRGKNESLTFRLHE 323
Cdd:PRK02224   221 EIERYEEQREQARETRDEADEVLEEHE----ERREELETLEAEIEDL---RETIAETE---REREELAEEVRDLRERLEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  324 TLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKAT----------QQWVEKQAHLEK 393
Cdd:PRK02224   291 LEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLRedaddleeraEELREEAAELES 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  394 ELSTALQDKKCLEEKNEILQGKLSQLEERLAQLP----------ESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQA 463
Cdd:PRK02224   371 ELEEAREAVEDRREEIEELEEEIEELRERFGDAPvdlgnaedflEELREERDELREREAELEATLRTARERVEEAEALLE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  464 RVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQA--QGAKLNAQVASLTAELTTLSA 541
Cdd:PRK02224   451 AGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAedRIERLEERREDLEELIAERRE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  542 TLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQasqgLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQ 621
Cdd:PRK02224   531 TIEEKRERAEELRERAAELEAEAEEKREAAAE----AEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAED 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  622 E-TSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAqdsaqNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQT 700
Cdd:PRK02224   607 EiERLREKREALAELNDERRERLAEKRERKRELEAEFDE-----ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQA 681

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1196773644  701 QVAALEARLKAEQQKATEREKVAQEKAQLqEQLWSLEESLKITKGSLEEE 750
Cdd:PRK02224   682 EIGAVENELEELEELRERREALENRVEAL-EALYDEAEELESMYGDLRAE 730
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 690-944 4.98e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.38  E-value: 4.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  690 AAHQEQCEAQTQVAALEARLKAEQQkatEREKVAQEKAQLQEQLWSLEESLKitkgsleeekcRAAAALEEHQHHISEME 769
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEK---ELAALKKEEKALLKQLAALERRIA-----------ALARRIRALEQELAALE 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  770 AESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVEllvkevktwrkryEDS 849
Cdd:COG4942     83 AELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAP-------------ARR 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  850 QQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDL 929
Cdd:COG4942    150 EQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229

                          250
                   ....*....|....*
gi 1196773644  930 STLQEKMAATSKEVA 944
Cdd:COG4942    230 ARLEAEAAAAAERTP 244
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 857-1716 5.26e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 55.34  E-value: 5.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  857 GLQEQLTTLKEEYEKSCQELRETKEKMagIEAHSEL-QIGQHQSELAQL------HANLARALQQVQEKENRAQklaDDL 929
Cdd:COG3096    282 ELSERALELRRELFGARRQLAEEQYRL--VEMARELeELSARESDLEQDyqaasdHLNLVQTALRQQEKIERYQ---EDL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  930 STLQEKMAATSKEVARLEALVRKAGEQQETASLELlkeppktrdresewveEQQGQQLCSTQAALRAMEREA---EQMGT 1006
Cdd:COG3096    357 EELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEV----------------DSLKSQLADYQQALDVQQTRAiqyQQAVQ 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1007 ELEKLRAALMESQGQQQEERGQQEREVAR---LTQERGQAEADLALEKAAKAELEMRLQnalneqqaefanLQEALSRAL 1083
Cdd:COG3096    421 ALEKARALCGLPDLTPENAEDYLAAFRAKeqqATEEVLELEQKLSVADAARRQFEKAYE------------LVCKIAGEV 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1084 SEKEGKDQELSKLCEQEavqrmELKELLQTVEQLKAQLAKKEK--EQQQSARGASGENASGMGTQSEAVGKMEALRAkvs 1161
Cdd:COG3096    489 ERSQAWQTARELLRRYR-----SQQALAQRLQQLRAQLAELEQrlRQQQNAERLLEEFCQRIGQQLDAAEELEELLA--- 560

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1162 kleqqcqqqqeEADSLARSLESERAFHVERDRALETLQGQLEEKARELgysqAASASAQRELATLRAKAQDHSKAEEEWK 1241
Cdd:COG3096    561 -----------ELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKEL----AARAPAWLAAQDALERLREQSGEALADS 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1242 AQVARGQQEAVRKgslisslEEEVSILNRQVLEKEGE-SKELKRLVI---AESEKSQKLEERL--RLLQM--------ET 1307
Cdd:COG3096    626 QEVTAAMQQLLER-------EREATVERDELAARKQAlESQIERLSQpggAEDPRLLALAERLggVLLSEiyddvtleDA 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1308 ASNSARAAERSSAL--------REEVQSL-----------------------REEVEKQRAASENLRQ-------EL--- 1346
Cdd:COG3096    699 PYFSALYGPARHAIvvpdlsavKEQLAGLedcpedlyliegdpdsfddsvfdAEELEDAVVVKLSDRQwrysrfpEVplf 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1347 --ASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVsellpAKHLcqqlqaeQVAAEKRHREELEQskqaag 1424
Cdd:COG3096    779 grAAREKRLEELRAERDELAEQYAKASFDVQKLQRLHQAFSQFV-----GGHL-------AVAFAPDPEAELAA------ 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1425 gLRTELMRAQRELgelvplrqkvAEQERAAQQLRAEKASYAEQLSMLKKAHG---LLAEEnrGLGERanlgRQFLEVELD 1501
Cdd:COG3096    841 -LRQRRSELEREL----------AQHRAQEQQLRQQLDQLKEQLQLLNKLLPqanLLADE--TLADR----LEELREELD 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1502 QARE--KYIQElaavRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKvkvleerQRFQEERQKLTAQVEELSKKLA-DY 1578
Cdd:COG3096    904 AAQEaqAFIQQ----HGKALAQLEPLVAVLQSDPEQFEQLQADYLQAK-------EQQRRLKQQIFALSEVVQRRPHfSY 972

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1579 DQAskvqQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQL 1658
Cdd:COG3096    973 EDA----VGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQ 1048

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1196773644 1659 QKENKELRAEAERlgQELQQAGLKTKeaeQTCRHLTAQVRSLEAQVAHADQQLRELGK 1716
Cdd:COG3096   1049 ADAEAEERARIRR--DELHEELSQNR---SRRSQLEKQLTRCEAEMDSLQKRLRKAER 1101
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1190-1735 6.33e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.97  E-value: 6.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1190 ERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARgQQEAVRKGSLISSLEEEVSiLN 1269
Cdd:TIGR00618  212 CMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRAR-IEELRAQEAVLEETQERIN-RA 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1270 RQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSS---ALREEVQSLREEVEKQRAASENLrqEL 1346
Cdd:TIGR00618  290 RKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSieeQRRLLQTLHSQEIHIRDAHEVAT--SI 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1347 ASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGL 1426
Cdd:TIGR00618  368 REISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAI 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1427 RTELMRAQRELGELVPLRQKVAEQEraaqQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREK 1506
Cdd:TIGR00618  448 TCTAQCEKLEKIHLQESAQSLKERE----QQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNP 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1507 YIQELAAVRGdaETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQ 1586
Cdd:TIGR00618  524 GPLTRRMQRG--EQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTE 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1587 QKLKAFQAQGGESQQEAQRLQTQLNELQV-----QLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKE 1661
Cdd:TIGR00618  602 KLSEAEDMLACEQHALLRKLQPEQDLQDVrlhlqQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLA 681

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1196773644 1662 NKELRAEAERLG---QELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRelGKFQVASDALKSREPQAKPQL 1735
Cdd:TIGR00618  682 LQKMQSEKEQLTywkEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLA--AREDALNQSLKELMHQARTVL 756
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 512-1130 8.01e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.59  E-value: 8.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  512 EELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAglkqqaqKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQ 591
Cdd:TIGR00618  197 ELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQ-------QTQQSHAYLTQKREAQEEQLKKQQLLKQLRARI 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  592 KEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQ 671
Cdd:TIGR00618  270 EELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  672 REKAELSQKVEELHALIEAAHQEQCEAQTQvaaleaRLKAEQQKATEREKVAQEKAQLQEQLWSLE---ESLKITKGSLE 748
Cdd:TIGR00618  350 LHSQEIHIRDAHEVATSIREISCQQHTLTQ------HIHTLQQQKTTLTQKLQSLCKELDILQREQatiDTRTSAFRDLQ 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  749 EEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKArtsNNMA 828
Cdd:TIGR00618  424 GQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARL---LELQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  829 EREVELLVKEVKTWRKRYEDSQQGETQ---YGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIgQHQSELAQLH 905
Cdd:TIGR00618  501 EEPCPLCGSCIHPNPARQDIDNPGPLTrrmQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQ-QSFSILTQCD 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  906 ANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVAR----LEALVRKAGEQQETASLELLKEPPKTRDRE------ 975
Cdd:TIGR00618  580 NRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRklqpEQDLQDVRLHLQQCSQELALKLTALHALQLtltqer 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  976 ----SEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLrAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEK 1051
Cdd:TIGR00618  660 vrehALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEML-AQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARE 738

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1196773644 1052 AAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQ 1130
Cdd:TIGR00618  739 DALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDED 817
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 487-704 9.26e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 9.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  487 EEEKQQLASLITNLQSSISNLSQAKEElEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQ 566
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKE-EKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  567 SLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELD------ASRRDHAQQLATAAKAQETSLRERDAACQQLEALEK 640
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylkylaPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1196773644  641 EKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAA 704
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 578-877 9.46e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 53.97  E-value: 9.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  578 LRHQVEQLSGSLKQKeKQLEEAAR----ELDASRRDHAQQLATAAK--------AQETSLRERDAACQQLEALEKEKAAK 645
Cdd:pfam17380  301 LRQEKEEKAREVERR-RKLEEAEKarqaEMDRQAAIYAEQERMAMErereleriRQEERKRELERIRQEEIAMEISRMRE 379

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  646 LEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEA-QTQVAALEarlkaeQQKATEREKVAQ 724
Cdd:pfam17380  380 LERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEArQREVRRLE------EERAREMERVRL 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  725 EKAQLQEQLWSLEESlkitkgslEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLA 804
Cdd:pfam17380  454 EEQERQQQVERLRQQ--------EEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEER 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  805 ETHQAETKALRQELAKARTSNNMAER-EVELLVKEVKTWRKRYE-------------DSQQGETQYGLQEQLTTLKEEYE 870
Cdd:pfam17380  526 QKAIYEEERRREAEEERRKQQEMEERrRIQEQMRKATEERSRLEamereremmrqivESEKARAEYEATTPITTIKPIYR 605


                   ....*..
gi 1196773644  871 KSCQELR 877
Cdd:pfam17380  606 PRISEYQ 612
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
461-1127 9.60e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.15  E-value: 9.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  461 LQARVEMLE--NEQGQKEAQLLGERSHFEEEKQQLASLitnlqssisnlsQAKEELEQASQAQgAKLNAQVASLTAELTT 538
Cdd:COG4913    247 AREQIELLEpiRELAERYAAARERLAELEYLRAALRLW------------FAQRRLELLEAEL-EELRAELARLEAELER 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  539 LSATLQQQDQELaglkqqaqkkqaqlaqslqqqeqasQGLRHQVEQLSG----SLKQKEKQLEEAARELDASRRDHAQQL 614
Cdd:COG4913    314 LEARLDALREEL-------------------------DELEAQIRGNGGdrleQLEREIERLERELEERERRRARLEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  615 ATAAKAQETSLRErdaacqqLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHA---LIEAA 691
Cdd:COG4913    369 AALGLPLPASAEE-------FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERrksNIPAR 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  692 HQ---EQCEAQTQVAALEARLKAE--QQKATERE-KVAQEKAqlqeqLWSLEESLkitkgsLEEEKCRAAAA-------- 757
Cdd:COG4913    442 LLalrDALAEALGLDEAELPFVGEliEVRPEEERwRGAIERV-----LGGFALTL------LVPPEHYAAALrwvnrlhl 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  758 --------LEEHQHHISEMEAESRSLAEqhkqerkELE-EEKAKRRGLGVQLQQLAETHQAET-KALRQElAKARTSNNM 827
Cdd:COG4913    511 rgrlvyerVRTGLPDPERPRLDPDSLAG-------KLDfKPHPFRAWLEAELGRRFDYVCVDSpEELRRH-PRAITRAGQ 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  828 aerevellvkeVKTWRKRYE--DSQQGETQYGL----QEQLTTLKEEYEKSCQELRETKEKMAGIEAhselqigqhQSEL 901
Cdd:COG4913    583 -----------VKGNGTRHEkdDRRRIRSRYVLgfdnRAKLAALEAELAELEEELAEAEERLEALEA---------ELDA 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  902 AQLHANLARALQQVQEKENRAQKLADDLSTLQEKMA---ATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEW 978
Cdd:COG4913    643 LQERREALQRLAEYSWDEIDVASAEREIAELEAELErldASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  979 VEEQQGQQLCSTQAAlRAMEREAEQMGTELEKLRAALMESqgqqqeergqqerevARLTQERGQAEADLALEKAAKAELE 1058
Cdd:COG4913    723 EQAEEELDELQDRLE-AAEDLARLELRALLEERFAAALGD---------------AVERELRENLEERIDALRARLNRAE 786

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1059 MRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRME-LKELLQT-----VEQLKAQLAKKEKE 1127
Cdd:COG4913    787 EELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGLPEYEErFKELLNEnsiefVADLLSKLRRAIRE 861
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1190-1679 1.12e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.07  E-value: 1.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1190 ERDRALETLQGQLEEKARELGYSQAASASAQRELATLRA-KAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSIL 1268
Cdd:pfam12128  248 QEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAeLNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEAL 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1269 NRQVLEKEGESKE-----LKRLVIAESEKSQkLEERLRLL----QMETASNSARAAERSSALREEVQSL-------REEV 1332
Cdd:pfam12128  328 EDQHGAFLDADIEtaaadQEQLPSWQSELEN-LEERLKALtgkhQDVTAKYNRRRSKIKEQNNRDIAGIkdklakiREAR 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1333 EKQRAASENLRQELASQAEraEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLpakhlcqQLQAEQVAAEkRH 1412
Cdd:pfam12128  407 DRQLAVAEDDLQALESELR--EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLL-------QLENFDERIE-RA 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1413 REELEQSkqaagglRTELMRAQRELGELVPLRQKVAEQ----ERAAQQLRAEKASYAEQLSmlKKAHGLLA--------- 1479
Cdd:pfam12128  477 REEQEAA-------NAEVERLQSELRQARKRRDQASEAlrqaSRRLEERQSALDELELQLF--PQAGTLLHflrkeapdw 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1480 EENRG-LGERANLGRQFLEVELDQAREKYIQELAAVRGDAEtrlAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQ 1558
Cdd:pfam12128  548 EQSIGkVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLK---RIDVPEWAASEEELRERLDKAEEALQSAREKQAAAE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1559 EERQKLTAQVEELSKKLADYDQASKVQQQKLkafQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKakthy 1638
Cdd:pfam12128  625 EQLVQANGELEKASREETFARTALKNARLDL---RRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDK----- 696

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 1196773644 1639 dakkqqnqelqEQLQGLEQLQKENKELRAEAERLGQELQQA 1679
Cdd:pfam12128  697 -----------KHQAWLEEQKEQKREARTEKQAYWQVVEGA 726
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 808-1163 1.29e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 53.90  E-value: 1.29e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  808 QAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYglqeqlTTLKEEYEKSCQELRETKEKMAGI- 886
Cdd:PRK10929    22 APDEKQITQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQY------QQVIDNFPKLSAELRQQLNNERDEp 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  887 -EAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEalvRKAGEQQETASLell 965
Cdd:PRK10929    96 rSVPPNMSTDALEQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIE---RRLQTLGTPNTP--- 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  966 keppktrdresewVEEQQGQQLCSTQAALRAM--EREAEQMGT----ELEKLRAALMESQGQQQEERGQQEREvaRLTQE 1039
Cdd:PRK10929   170 -------------LAQAQLTALQAESAALKALvdELELAQLSAnnrqELARLRSELAKKRSQQLDAYLQALRN--QLNSQ 234

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1040 RgQAEADLALEKAakaelEMrlqnaLNEQQAEfanlqeaLSRALSEKEGKDQELSKLCEQEAvQRMELKELLQtveqlka 1119
Cdd:PRK10929   235 R-QREAERALEST-----EL-----LAEQSGD-------LPKSIVAQFKINRELSQALNQQA-QRMDLIASQQ------- 288

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1196773644 1120 QLAKKEKEQQQSARGASGENASGMGTqSEAVGkmEALRAKVSKL 1163
Cdd:PRK10929   289 RQAASQTLQVRQALNTLREQSQWLGV-SNALG--EALRAQVARL 329
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1258-1714 1.82e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 53.19  E-value: 1.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1258 ISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLlqmeTASNSARAAERSSALREEVQSLREEVEKQRA 1337
Cdd:pfam05483  235 INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKL----QDENLKELIEKKDHLTKELEDIKMSLQRSMS 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1338 ASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLpakhlcqqlqaeqvaaeKRHREELE 1417
Cdd:pfam05483  311 TQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELL-----------------RTEQQRLE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1418 QSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEENRGLGERAnlgrqfle 1497
Cdd:pfam05483  374 KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAED----EKLLDEKKQFEKIAEELKGKEQEL-------- 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1498 VELDQAREKYIQELaavrgdaETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEerqrFQEERQKLTAQVEELSKKLAD 1577
Cdd:pfam05483  442 IFLLQAREKEIHDL-------EIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIE----LTAHCDKLLLENKELTQEASD 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1578 YDQASKVQQQKLKAFQAQGGESQQEAQRLQ---TQL-NELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQ 1653
Cdd:pfam05483  511 MTLELKKHQEDIINCKKQEERMLKQIENLEekeMNLrDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMK 590

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1654 GLEQ----LQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLREL 1714
Cdd:pfam05483  591 ILENkcnnLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEI 655
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 235-818 1.92e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.30  E-value: 1.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  235 GDILQTPQFQmrrlkkqlADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDR-LALLNEKQAASPLE-PRELEELRG 312
Cdd:pfam12128  344 ADQEQLPSWQ--------SELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRdIAGIKDKLAKIREArDRQLAVAED 415

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  313 KNESLTFRLHEtlkqcqdlktekgQMDRKINQLSEENgdlsfklREFASNLQQLQGALNELTEEHSKATQQ--WVEKQAH 390
Cdd:pfam12128  416 DLQALESELRE-------------QLEAGKLEFNEEE-------YRLKSRLGELKLRLNQATATPELLLQLenFDERIER 475

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  391 LEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQL--------ESLKQEAATLATNNTQLQ 462
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqagtllHFLRKEAPDWEQSIGKVI 555

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  463 AR--------VEMLENEQGQKEAQLLGERSHFEE-EKQQLASLITNLQSSISNLS---QAKEELEQASQAQGAKLNAQVA 530
Cdd:pfam12128  556 SPellhrtdlDPEVWDGSVGGELNLYGVKLDLKRiDVPEWAASEEELRERLDKAEealQSAREKQAAAEEQLVQANGELE 635

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  531 SLTAELTTLSATLQQQDQELAG----LKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDAS 606
Cdd:pfam12128  636 KASREETFARTALKNARLDLRRlfdeKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTE 715

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  607 RRDHAQQLATAAKAQETSLRerdaacQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEelha 686
Cdd:pfam12128  716 KQAYWQVVEGALDAQLALLK------AAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIE---- 785

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  687 liEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHIS 766
Cdd:pfam12128  786 --RIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLR 863

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1196773644  767 EMEAESRSLAEQHK-QERKELEEEKAKRRGlgvQLQQLAETHQAETKALRQEL 818
Cdd:pfam12128  864 GLRCEMSKLATLKEdANSEQAQGSIGERLA---QLEDLKLKRDYLSESVKKYV 913
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 293-840 1.95e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 53.19  E-value: 1.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  293 LNEKQAASPLEPRELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNE 372
Cdd:pfam05483  235 INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKA 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  373 LTEEHSKATQQWVEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQlpESPRQEKGE----VLGDVLQLESLK 448
Cdd:pfam05483  315 LEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRT--EQQRLEKNEdqlkIITMELQKKSSE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  449 QEAATLATNNTQLQarVEMLENEQGQKEaQLLGERSHFEeekqQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQ 528
Cdd:pfam05483  393 LEEMTKFKNNKEVE--LEELKKILAEDE-KLLDEKKQFE----KIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTS 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  529 VASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLE--EAARELDAS 606
Cdd:pfam05483  466 EEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKqiENLEEKEMN 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  607 RRDHAQQLATAAKAQETSLRerdaaCQQLEALEKEKAAKLEILQQQLQaaneaQDSAQNSVTQAQREKAELSQKVEELHA 686
Cdd:pfam05483  546 LRDELESVREEFIQKGDEVK-----CKLDKSEENARSIEYEVLKKEKQ-----MKILENKCNNLKKQIENKNKNIEELHQ 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  687 LIEAAHQEQCEAQTQVAALEARL-KAEQQKATEREKVAQEKAQLQEQLwsleESLKITKGSLEEEKCRAAAALEEH---- 761
Cdd:pfam05483  616 ENKALKKKGSAENKQLNAYEIKVnKLELELASAKQKFEEIIDNYQKEI----EDKKISEEKLLEEVEKAKAIADEAvklq 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  762 -------QHHISEMEAesrsLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQA----ETKALRQELAKARTSNNMAER 830
Cdd:pfam05483  692 keidkrcQHKIAEMVA----LMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAaleiELSNIKAELLSLKKQLEIEKE 767

                          570
                   ....*....|
gi 1196773644  831 EVELLVKEVK 840
Cdd:pfam05483  768 EKEKLKMEAK 777
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1228-1356 2.27e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 52.94  E-value: 2.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1228 AKAQDHSKAEEEWKAQVARGQQEAVRkgsliSSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMEt 1307
Cdd:COG2433    383 EELIEKELPEEEPEAEREKEHEEREL-----TEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE- 456

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1196773644 1308 ASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELasqaERAEEL 1356
Cdd:COG2433    457 ERREIRKDREISRLDREIERLERELEEERERIEELKRKL----ERLKEL 501
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 758-1509 2.74e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.81  E-value: 2.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  758 LEEHQHHISEMEAESRSLAEQHkqerkelEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVK 837
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELH-------EKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVH 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  838 EVKTWRKRYEDS-QQGETQYglqEQLTTLKEEYEKSCQELRETkekMAGIEAHSELQIGQHQSELAQLHANLARALQQV- 915
Cdd:pfam15921  153 ELEAAKCLKEDMlEDSNTQI---EQLRKMMLSHEGVLQEIRSI---LVDFEEASGKKIYEHDSMSTMHFRSLGSAISKIl 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  916 QEKENRAQKLADDLSTLQEKMAATSKEVA-RLEALVRKAGEQQETASLE-------LLKEPPKTRDR------ESEWVEE 981
Cdd:pfam15921  227 RELDTEISYLKGRIFPVEDQLEALKSESQnKIELLLQQHQDRIEQLISEheveitgLTEKASSARSQansiqsQLEIIQE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  982 QQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQaeadLALEKAAKAELEMRL 1061
Cdd:pfam15921  307 QARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQ----FSQESGNLDDQLQKL 382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1062 QNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQlAKKEKEQQQSArgASGENAS 1141
Cdd:pfam15921  383 LADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSE-CQGQMERQMAA--IQGKNES 459

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1142 gMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALET-------LQGQLEEKARELGYSQA 1214
Cdd:pfam15921  460 -LEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAtnaeitkLRSRVDLKLQELQHLKN 538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1215 AS---ASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESE 1291
Cdd:pfam15921  539 EGdhlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDA 618

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1292 KSQKLEERLRLLQMETASNSARAAERSSALREevqsLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFfqkE 1371
Cdd:pfam15921  619 KIRELEARVSDLELEKVKLVNAGSERLRAVKD----IKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEM---E 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1372 QALSALQLEHTSTQalvSELLPAKHLCQQLQAEQVAAEKrhreeleqskqAAGGLRTELMrAQRelGELVPLRQKVAEQE 1451
Cdd:pfam15921  692 TTTNKLKMQLKSAQ---SELEQTRNTLKSMEGSDGHAMK-----------VAMGMQKQIT-AKR--GQIDALQSKIQFLE 754

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1196773644 1452 RAAQQLRAEKASYAEQLSMLKKAHGLLA-EENRGLGERANLGRQ---------FLEVELDQAREKYIQ 1509
Cdd:pfam15921  755 EAMTNANKEKHFLKEEKNKLSQELSTVAtEKNKMAGELEVLRSQerrlkekvaNMEVALDKASLQFAE 822
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 417-966 2.94e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 2.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  417 SQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQkeaqllgershFEEEKQQLASL 496
Cdd:TIGR04523  120 NKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNL-----------LEKEKLNIQKN 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  497 ITNLQSSISNLSQAKEELEQASQAQgAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQ 576
Cdd:TIGR04523  189 IDKIKNKLLKLELLLSNLKKKIQKN-KSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  577 GLRH---QVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQetslrerdaacqqlealEKEKAAKLEILQQQL 653
Cdd:TIGR04523  268 QLSEkqkELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSE-----------------LKNQEKKLEEIQNQI 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  654 QAANEAQDSAQNSVTQAQREK-------AELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQek 726
Cdd:TIGR04523  331 SQNNKIISQLNEQISQLKKELtnsesenSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQ-- 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  727 aQLQEQLwsleESLKITKGSLEEEkcraaaaLEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLA-- 804
Cdd:TIGR04523  409 -QKDEQI----KKLQQEKELLEKE-------IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSrs 476

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  805 -ETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGetqyglQEQLTTLKEEYEKSCQELRETKEKM 883
Cdd:TIGR04523  477 iNKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEK------IEKLESEKKEKESKISDLEDELNKD 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  884 AGIEAHSEL--QIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETAS 961
Cdd:TIGR04523  551 DFELKKENLekEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLS 630


                   ....*
gi 1196773644  962 LELLK 966
Cdd:TIGR04523  631 SIIKN 635
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 245-550 2.99e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 2.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  245 MRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAasplepRELEELRGKNESLTFRLHET 324
Cdd:TIGR04523  309 NKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQ------RELEEKQNEIEKLKKENQSY 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  325 LKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQ---WVEKQAHLEKELSTALQD 401
Cdd:TIGR04523  383 KQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEikdLTNQDSVKELIIKNLDNT 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  402 KKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLG 481
Cdd:TIGR04523  463 RESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISD 542

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1196773644  482 ERSHFEEEKQ-----QLASLITNLQSSISNLSQAKEELEQAS---QAQGAKLNAQVASLTAELTTLSATLQQQDQEL 550
Cdd:TIGR04523  543 LEDELNKDDFelkkeNLEKEIDEKNKEIEELKQTQKSLKKKQeekQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1276-1704 3.93e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 3.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1276 EGESKEL-KRLVIAESEKSQKLEERLRL-LQMETASNSARAA----ERSSALREEVQSLREEVEKQRAA-------SENL 1342
Cdd:PRK02224   198 EKEEKDLhERLNGLESELAELDEEIERYeEQREQARETRDEAdevlEEHEERREELETLEAEIEDLRETiaetereREEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1343 RQELASQAERAEELGQELkawqekffqkEQALSALQLEHTSTQALvsellpakhlcQQLQAEQVAAEKRHREELEQSKQA 1422
Cdd:PRK02224   278 AEEVRDLRERLEELEEER----------DDLLAEAGLDDADAEAV-----------EARREELEDRDEELRDRLEECRVA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1423 AGGLRTElmrAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANlgrqFLEVELDQ 1502
Cdd:PRK02224   337 AQAHNEE---AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG----DAPVDLGN 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1503 ArEKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAK-------------VKVLEERQ----RFQEERQKLT 1565
Cdd:PRK02224   410 A-EDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphVETIEEDRerveELEAELEDLE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1566 AQVEELSKKLADYDQASKVQQQ------------KLKAFQAQGGESQQE-AQRLQTQLNELQVQLSQKEQAAEHYKVQME 1632
Cdd:PRK02224   489 EEVEEVEERLERAEDLVEAEDRierleerredleELIAERRETIEEKRErAEELRERAAELEAEAEEKREAAAEAEEEAE 568

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1633 KAKTH---YDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQV 1704
Cdd:PRK02224   569 EAREEvaeLNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEF 643
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
664-1349 4.35e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.99  E-value: 4.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  664 QNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKIT 743
Cdd:PRK03918   192 EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEEL 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  744 KGSLEEekcraaaaLEEHQHHISEMEAEsrslAEQHKQERKELEEEKAKRRGLGVQLQQLAEthqaETKALRQELAKArt 823
Cdd:PRK03918   272 KKEIEE--------LEEKVKELKELKEK----AEEYIKLSEFYEEYLDELREIEKRLSRLEE----EINGIEERIKEL-- 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  824 snNMAEREVELLVKEVKTWRKRYedsqqgetqyglqeqlttlkEEYEKSCQELRETKEKMAGIEahselqigQHQSELAQ 903
Cdd:PRK03918   334 --EEKEERLEELKKKLKELEKRL--------------------EELEERHELYEEAKAKKEELE--------RLKKRLTG 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  904 LhaNLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLealvrkageqqETASLELLKEPPKTRDRESEWVEEQQ 983
Cdd:PRK03918   384 L--TPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKEL-----------KKAIEELKKAKGKCPVCGRELTEEHR 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  984 GQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERgqqerevaRLTQERGQAEADLALEKaakaELEMRLQN 1063
Cdd:PRK03918   451 KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKES--------ELIKLKELAEQLKELEE----KLKKYNLE 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1064 ALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAvqrmELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGM 1143
Cdd:PRK03918   519 ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKK----KLAELEKKLDELEEELAELLKELEELGFESVEELEERL 594

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1144 GTQSEAVGKMEALRAKVSKLEQQCQQQqeeaDSLARSLESERAFHVERDRALETLQGQLEEKARElgYSQaasasaqrel 1223
Cdd:PRK03918   595 KELEPFYNEYLELKDAEKELEREEKEL----KKLEEELDKAFEELAETEKRLEELRKELEELEKK--YSE---------- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1224 atlrakaQDHSKAEEEWkaqvargqqeaVRKGSLISSLEEEVSILNRQVLEKEGESKELKRlviaESEKSQKLEERLRLL 1303
Cdd:PRK03918   659 -------EEYEELREEY-----------LELSRELAGLRAELEELEKRREEIKKTLEKLKE----ELEEREKAKKELEKL 716

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*.
gi 1196773644 1304 QmetasnsaRAAERSSALREEVQSLREEVeKQRAASEnlRQELASQ 1349
Cdd:PRK03918   717 E--------KALERVEELREKVKKYKALL-KERALSK--VGEIASE 751
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 407-631 4.86e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 4.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  407 EKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGERSHF 486
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  487 EEEKQQLASLITNLQSSiSNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQ 566
Cdd:COG4942    100 EAQKEELAELLRALYRL-GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1196773644  567 SLQQQEQASQGL---RHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAA 631
Cdd:COG4942    179 LLAELEEERAALealKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1305-1704 5.51e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.88  E-value: 5.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1305 METASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALsALQLEHTST 1384
Cdd:COG3096    274 MRHANERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTAL-RQQEKIERY 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1385 QALVSELlpAKHLCQQLQAEQVAAEKR--HREELEQSKQAAGGLRTELMRAQRELGEL----VPLRQKVAEQERAAQQLR 1458
Cdd:COG3096    353 QEDLEEL--TERLEEQEEVVEEAAEQLaeAEARLEAAEEEVDSLKSQLADYQQALDVQqtraIQYQQAVQALEKARALCG 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1459 AEK---ASYAEQLSMLKKAHGLLAEENRGLGERANLGrqflevelDQAREKYIQELAAVR---GDAETRLA-EMRQEVQS 1531
Cdd:COG3096    431 LPDltpENAEDYLAAFRAKEQQATEEVLELEQKLSVA--------DAARRQFEKAYELVCkiaGEVERSQAwQTARELLR 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1532 TTHELEVMTAKYEGAKVKVLEERQRFqEERQKLTAQVEELSKKLA-DYDQASKVQQQKLkafqaqggESQQEAQRLQTQL 1610
Cdd:COG3096    503 RYRSQQALAQRLQQLRAQLAELEQRL-RQQQNAERLLEEFCQRIGqQLDAAEELEELLA--------ELEAQLEELEEQA 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1611 NELQVQLSQKEQAAEHYKVQMEKAkthydakKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTC 1690
Cdd:COG3096    574 AEAVEQRSELRQQLEQLRARIKEL-------AARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVER 646

                          410
                   ....*....|....
gi 1196773644 1691 RHLTAQVRSLEAQV 1704
Cdd:COG3096    647 DELAARKQALESQI 660
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1188-1677 5.60e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 5.60e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1188 HVERDRALETLQGQLEEkarelgySQAASASAQRELATLRAKAQDHSKAEEEwkaqvARGQQEAVRKGSLISSLEEEVSI 1267
Cdd:PRK02224   246 HEERREELETLEAEIED-------LRETIAETEREREELAEEVRDLRERLEE-----LEEERDDLLAEAGLDDADAEAVE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1268 LNRQVLEKEgeskelkrlviaESEKSQKLEERlRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELA 1347
Cdd:PRK02224   314 ARREELEDR------------DEELRDRLEEC-RVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1348 SQAERAEELGQELKAWQEKFFQKEQALSALQLEHtstQALVSELLPAKHLCQQLQAEQVAAEKRHREE---LEQSKQAAG 1424
Cdd:PRK02224   381 DRREEIEELEEEIEELRERFGDAPVDLGNAEDFL---EELREERDELREREAELEATLRTARERVEEAealLEAGKCPEC 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1425 GLRTELMRAQRELGElvpLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVE--LDQ 1502
Cdd:PRK02224   458 GQPVEGSPHVETIEE---DRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRetIEE 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1503 AREKyIQELAAVRGDAETRLAEMRQEVQSTTHElevmtAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADYDQAS 1582
Cdd:PRK02224   535 KRER-AEELRERAAELEAEAEEKREAAAEAEEE-----AEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEI 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1583 KVQQQKLKAFQAQGGESQQEAQRLQTQLNELQV--------QLSQKEQAAEHYkvqMEKAKTHYDAKKQQNQELQEQLQG 1654
Cdd:PRK02224   609 ERLREKREALAELNDERRERLAEKRERKRELEAefdearieEAREDKERAEEY---LEQVEEKLDELREERDDLQAEIGA 685

                          490       500
                   ....*....|....*....|...
gi 1196773644 1655 LEQLQKENKELRAEAERLGQELQ 1677
Cdd:PRK02224   686 VENELEELEELRERREALENRVE 708
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1181-1437 6.53e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 51.59  E-value: 6.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1181 LESERAFHVERDRA------LETLQGQLEEKARELgysqaasASAQRELATLRAKAQDHSKAeeewkaQVARGQQEAVRK 1254
Cdd:PRK10929   119 LEKSRQAQQEQDRAreisdsLSQLPQQQTEARRQL-------NEIERRLQTLGTPNTPLAQA------QLTALQAESAAL 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1255 GSLISSLE-EEVSILNRQvlekegeskELKRLviaESEKSQKLEERL--RLLQMETASNSAR------AAERSSALREEV 1325
Cdd:PRK10929   186 KALVDELElAQLSANNRQ---------ELARL---RSELAKKRSQQLdaYLQALRNQLNSQRqreaerALESTELLAEQS 253

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1326 QSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSAL----QLEHTST---QALVSEL--LPAKH 1396
Cdd:PRK10929   254 GDLPKSIVAQFKINRELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTLreqsQWLGVSNalgEALRAQVarLPEMP 333

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1196773644 1397 LCQQLQAE--QVAAEKRHREEL-------EQSKQAAGGLRT--------ELMRAQREL 1437
Cdd:PRK10929   334 KPQQLDTEmaQLRVQRLRYEDLlnkqpqlRQIRQADGQPLTaeqnrildAQLRTQREL 391
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
305-961 8.48e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 8.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  305 RELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEehskatqqw 384
Cdd:PRK03918   172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEE--------- 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  385 vekqahLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLpESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQAR 464
Cdd:PRK03918   243 ------LEKELESLEGSKRKLEEKIRELEERIEELKKEIEEL-EEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKR 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  465 VEMLENEQGQKEAQlLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQaqgakLNAQVASLTAELTTLSATLQ 544
Cdd:PRK03918   316 LSRLEEEINGIEER-IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKA-----KKEELERLKKRLTGLTPEKL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  545 QQDQELAGLKQQAQKKQaqlaqslqqqeqasqglRHQVEQLSGSLKQKEKQLEEAARELDASRR-----------DHAQQ 613
Cdd:PRK03918   390 EKELEELEKAKEEIEEE-----------------ISKITARIGELKKEIKELKKAIEELKKAKGkcpvcgrelteEHRKE 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  614 LATAAKAQETSLRERDAacqqlEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQK--VEELhaliEAA 691
Cdd:PRK03918   453 LLEEYTAELKRIEKELK-----EIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKynLEEL----EKK 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  692 HQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEekcRAAAALEEHQHHISEMEAE 771
Cdd:PRK03918   524 AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEE---LGFESVEELEERLKELEPF 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  772 SRSLAEQhKQERKELEEEKAKRrglgvqlqqlaethqaetKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDsqq 851
Cdd:PRK03918   601 YNEYLEL-KDAEKELEREEKEL------------------KKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE--- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  852 getqyglqeqlttlkEEYEKSCQELRETKEKMAGIEAHSElQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLST 931
Cdd:PRK03918   659 ---------------EEYEELREEYLELSRELAGLRAELE-ELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALER 722

                          650       660       670
                   ....*....|....*....|....*....|..
gi 1196773644  932 LQEkmaaTSKEVARLEALVRKAG--EQQETAS 961
Cdd:PRK03918   723 VEE----LREKVKKYKALLKERAlsKVGEIAS 750
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 242-517 8.87e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 8.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  242 QFQMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRL-ALLNEKQAASPLEPRELEELRGKNESLTFR 320
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALrEALDELRAELTLLNEEAANLRERLESLERR 832

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  321 LHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQ---GALNELTEEHSKATQQWVEKQAHLEKELST 397
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLnerASLEEALALLRSELEELSEELRELESKRSE 912

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  398 ALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAAtlatnnTQLQARVEMLENEQGQKEA 477
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDE------EEARRRLKRLENKIKELGP 986

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 1196773644  478 QLLGERSHFEEEKQQLasliTNLQSSISNLSQAKEELEQA 517
Cdd:TIGR02168  987 VNLAAIEEYEELKERY----DFLTAQKEDLTEAKETLEEA 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1413-1714 1.32e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 1.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1413 REELEQSKQAAGGLRTELMRAQRELGELvplrQKVAEQERAAQQLRAEKASYaEQLSMLKKAHGLLAEENRGLGERANLG 1492
Cdd:TIGR02169  176 LEELEEVEENIERLDLIIDEKRQQLERL----RREREKAERYQALLKEKREY-EGYELLKEKEALERQKEAIERQLASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1493 RQF--LEVELDQaREKYIQELAAVRGDAETRLAEMRQE----VQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTA 1566
Cdd:TIGR02169  251 EELekLTEEISE-LEKRLEEIEQLLEELNKKIKDLGEEeqlrVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1567 QVEELSKKLADYDQASKVQQQKLKAFQAqggesqqEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHydakkqqnq 1646
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTE-------EYAELKEELEDLRAELEEVDKEFAETRDELKDYREK--------- 393

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1196773644 1647 elqeqlqgLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLREL 1714
Cdd:TIGR02169  394 --------LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ 453
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1278-1705 1.35e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1278 ESKELKRLVIAESEKSQKLEERLRLLQmETASNSARAAERSSALREEVQSLREEVEKQRAASE--NLRQELASQAERAEE 1355
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQLLPLYQEleALEAELAELPERLEE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1356 LGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVaaeKRHREELEQSKQAAGGLRTELMRAQR 1435
Cdd:COG4717    151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEEL---EELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1436 ELGELVPLRQKVAEQERAaQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYIQELAAVR 1515
Cdd:COG4717    228 ELEQLENELEAAALEERL-KEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1516 GDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQrfqEERQKLTAQVEELSKKLaDYDQASKVQQQKLKAFQA- 1594
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRI---EELQELLREAEELEEEL-QLEELEQEIAALLAEAGVe 382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1595 ------QGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQelqeqlqgLEQLQKENKELRAE 1668
Cdd:COG4717    383 deeelrAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEE--------LEELEEELEELREE 454

                          410       420       430
                   ....*....|....*....|....*....|....*....
gi 1196773644 1669 AERLGQELQQAGLKTK--EAEQTCRHLTAQVRSLEAQVA 1705
Cdd:COG4717    455 LAELEAELEQLEEDGElaELLQELEELKAELRELAEEWA 493
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 986-1626 1.45e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 1.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  986 QLCSTQAALRAMEReaeQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLA--------LEKAAKAEL 1057
Cdd:pfam12128  259 RLSHLHFGYKSDET---LIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAkdrseleaLEDQHGAFL 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1058 EMRLQNALNEQQAE--FANLQEALSRALSEKEGKDQELsklceQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGA 1135
Cdd:pfam12128  336 DADIETAAADQEQLpsWQSELENLEERLKALTGKHQDV-----TAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQL 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1136 SGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARS-------LESERAFHVERDRALETLqgqleEKARE 1208
Cdd:pfam12128  411 AVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQatatpelLLQLENFDERIERAREEQ-----EAANA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1209 lgySQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAV-----RKGSLISSLEEEVSiLNRQVLEKEGESKELK 1283
Cdd:pfam12128  486 ---EVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELElqlfpQAGTLLHFLRKEAP-DWEQSIGKVISPELLH 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1284 RL----VIAESEKSQKLE---ERLRLLQMETASnsarAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEEL 1356
Cdd:pfam12128  562 RTdldpEVWDGSVGGELNlygVKLDLKRIDVPE----WAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKA 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1357 GQELKAWQEKFFQKEQALSALQLEHTS-----TQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELM 1431
Cdd:pfam12128  638 SREETFARTALKNARLDLRRLFDEKQSekdkkNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQ 717

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1432 RAQRELGElvplrQKVAEQERAAQQLRAEKASYAEQLSMLKKAHgllAEENRGLGeranlgrqfleveldqAREKYIQEL 1511
Cdd:pfam12128  718 AYWQVVEG-----ALDAQLALLKAAIAARRSGAKAELKALETWY---KRDLASLG----------------VDPDVIAKL 773

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1512 AAVRGDAETRLAEMRQEVQSTTHELEVMTAKYegakvkvLEERQRFQEERQKLTAQVEELSKKLADYDQASKVQqqkLKA 1591
Cdd:pfam12128  774 KREIRTLERKIERIAVRRQEVLRYFDWYQETW-------LQRRPRLATQLSNIERAISELQQQLARLIADTKLR---RAK 843

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1196773644 1592 FQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEH 1626
Cdd:pfam12128  844 LEMERKASEKQQVRLSENLRGLRCEMSKLATLKED 878
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 585-822 2.06e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  585 LSGSLKQKEKQLEEAARELDASRrdhaQQLATAAKAQETSLRERDAACQQLEALEKekaaKLEILQQQLQAANEAQDSAQ 664
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQ----QEIAELEKELAALKKEEKALLKQLAALER----RIAALARRIRALEQELAALE 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  665 NSVTQAQREKAELSQKVEELHALIEAAHQEQcEAQTQVAALEARLKAEQQKATER-----EKVAQEKAQLQEQLWSLEES 739
Cdd:COG4942     83 AELAELEKEIAELRAELEAQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRrlqylKYLAPARREQAEELRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  740 LKITKGSLEEEKCRAAAALEEHQHHISEMEAEsrslAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELA 819
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEAL----KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237


                   ...
gi 1196773644  820 KAR 822
Cdd:COG4942    238 AAA 240
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 298-522 2.33e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  298 AASPLEPRELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEH 377
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  378 SKATQQWVEKQAHLEKELStALQDKKCLEEKNEILQGK-----------LSQLEERLAQLPESPRQEKGEVLGDVLQLES 446
Cdd:COG4942     93 AELRAELEAQKEELAELLR-ALYRLGRQPPLALLLSPEdfldavrrlqyLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1196773644  447 LKQEAATLATNNTQLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQG 522
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1439-1634 2.35e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1439 ELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYIQELAAVRGDA 1518
Cdd:COG4942     28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-ELEKEIAELRAELEAQKEEL 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1519 ETRLAEMRQEVQSTTHEL---------EVMTAKYEGAKVKVLEER-QRFQEERQKLTAQVEELSKKLADYDQASKVQQQK 1588
Cdd:COG4942    107 AELLRALYRLGRQPPLALllspedfldAVRRLQYLKYLAPARREQaEELRADLAELAALRAELEAERAELEALLAELEEE 186

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1196773644 1589 LKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKA 1634
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 240-684 3.49e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 3.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  240 TPQFQMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQI-SMMQQRIDRLALLNEKQAASPLEPRELEELRGKNESLT 318
Cdd:TIGR00618  448 TCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKkAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT 527

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  319 FRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEKELSTA 398
Cdd:TIGR00618  528 RRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAE 607

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  399 LQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEAQ 478
Cdd:TIGR00618  608 DMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQS 687

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  479 LLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQvasltaelttlSATLQQQDQELAGLKQQAQ 558
Cdd:TIGR00618  688 EKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAR-----------EDALNQSLKELMHQARTVL 756

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  559 KKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEAL 638
Cdd:TIGR00618  757 KARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSR 836

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 1196773644  639 EKEKAAKLEILQQQLQAANEAQDSAQnsvtQAQREKAELSQKVEEL 684
Cdd:TIGR00618  837 LEEKSATLGEITHQLLKYEECSKQLA----QLTQEQAKIIQLSDKL 878
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 483-1253 3.66e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.96  E-value: 3.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  483 RSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQA 562
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVH 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  563 QLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEE--------------AARELDASRRDHAQQLATAAKAQetsLRER 628
Cdd:pfam15921  153 ELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEirsilvdfeeasgkKIYEHDSMSTMHFRSLGSAISKI---LREL 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  629 DAACQ-----------QLEALEKEKAAKLEILQQQlqaaneAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQE--- 694
Cdd:pfam15921  230 DTEISylkgrifpvedQLEALKSESQNKIELLLQQ------HQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQlei 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  695 -QCEAQTQVAALEARLKAEQQKATE-REKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEaes 772
Cdd:pfam15921  304 iQEQARNQNSMYMRQLSDLESTVSQlRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQ--- 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  773 RSLAEQHKQERK-ELEEEKAKRrglgvqLQQLAETHQAETKALRQELakarTSNNMAEREVELLVKEVKTWRKRYEDSQQ 851
Cdd:pfam15921  381 KLLADLHKREKElSLEKEQNKR------LWDRDTGNSITIDHLRREL----DDRNMEVQRLEALLKAMKSECQGQMERQM 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  852 GETQYGLQ--EQLTTLKEEYEKSCQELRETKEKMAGieahSELQIGQHQSELAQLHANLaralqqvQEKENRAQKLADDL 929
Cdd:pfam15921  451 AAIQGKNEslEKVSSLTAQLESTKEMLRKVVEELTA----KKMTLESSERTVSDLTASL-------QEKERAIEATNAEI 519

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  930 STLQEKMAATSKEVARLealvRKAGE--QQETASLELLKEPPKTRDRESEWVEEQ---QGQQLCSTQAALRAMEREAEQM 1004
Cdd:pfam15921  520 TKLRSRVDLKLQELQHL----KNEGDhlRNVQTECEALKLQMAEKDKVIEILRQQienMTQLVGQHGRTAGAMQVEKAQL 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1005 GTELEKLRAALMESQGQQQEERGQQEREVARLTqergqaeaDLALEKaakaeleMRLQNALNEQQAEFANLQEALSRALS 1084
Cdd:pfam15921  596 EKEINDRRLELQEFKILKDKKDAKIRELEARVS--------DLELEK-------VKLVNAGSERLRAVKDIKQERDQLLN 660

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1085 EKEGKDQELSKLCEQEAVQRMELK----ELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKMEALRAKV 1160
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLKRNFRnkseEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKR 740

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1161 SKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQR---ELATLRAKAQDHSKAE 1237
Cdd:pfam15921  741 GQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRlkeKVANMEVALDKASLQF 820

                          810
                   ....*....|....*.
gi 1196773644 1238 EEWKAQVARGQQEAVR 1253
Cdd:pfam15921  821 AECQDIIQRQEQESVR 836
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
244-656 3.75e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 3.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  244 QMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAASPL---EPRELEELRGKNESLTFR 320
Cdd:COG4717     82 EAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAElaeLPERLEELEERLEELREL 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  321 LHETLKQCQDLKTEKGQMDRKINQLSEENGDlsfKLREFASNLQQLQGALNELTEEhskaTQQWVEKQAHLEKELSTALQ 400
Cdd:COG4717    162 EEELEELEAELAELQEELEELLEQLSLATEE---ELQDLAEELEELQQRLAELEEE----LEEAQEELEELEEELEQLEN 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  401 DKKCLEEKNEILQGKLSQ--------LEERLAQLPESPRQEKG------EVLGDVLQLESLKQEAATLATNNTQLQARVE 466
Cdd:COG4717    235 ELEAAALEERLKEARLLLliaaallaLLGLGGSLLSLILTIAGvlflvlGLLALLFLLLAREKASLGKEAEELQALPALE 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  467 MLENEQGQKEAQLLGERSHFE-EEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAElTTLSATLQQ 545
Cdd:COG4717    315 ELEEEELEELLAALGLPPDLSpEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDE-EELRAALEQ 393

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  546 QDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETS- 624
Cdd:COG4717    394 AEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAe 473

                          410       420       430
                   ....*....|....*....|....*....|...
gi 1196773644  625 -LRERDAACQQLEALEKEkAAKLEILQQQLQAA 656
Cdd:COG4717    474 lLQELEELKAELRELAEE-WAALKLALELLEEA 505
mukB PRK04863
chromosome partition protein MukB;
385-806 3.78e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 49.19  E-value: 3.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  385 VEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPE-----SPRQEKgeVLGDVLQLESLKQEAATLATNNT 459
Cdd:PRK04863   285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQdyqaaSDHLNL--VQTALRQQEKIERYQADLEELEE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  460 QLQARVEMLENEQGQKEAQllgershfEEEKQQLASLITNLQSSISNLSQAKEELE-------QASQA-QGAKLNAQVAS 531
Cdd:PRK04863   363 RLEEQNEVVEEADEQQEEN--------EARAEAAEEEVDELKSQLADYQQALDVQQtraiqyqQAVQAlERAKQLCGLPD 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  532 LTAE-LTTLSATLQQQDQELAglkqqaqkkqaqlaqslqqqeQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDH 610
Cdd:PRK04863   435 LTADnAEDWLEEFQAKEQEAT---------------------EELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSE 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  611 AQQLATAAKAQETSLRERDAACQQLEAlekeKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEA 690
Cdd:PRK04863   494 AWDVARELLRRLREQRHLAEQLQQLRM----RLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLES 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  691 AHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLkitkGSLEEEKCRAAAALEEHQHHISEMEA 770
Cdd:PRK04863   570 LSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQS----GEEFEDSQDVTEYMQQLLERERELTV 645

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1196773644  771 ESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAET 806
Cdd:PRK04863   646 ERDELAARKQALDEEIERLSQPGGSEDPRLNALAER 681
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
919-1578 4.45e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 4.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  919 ENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASlELLKEPPKTRDRESEWVEEQQG-----QQLCSTQAA 993
Cdd:PRK03918   161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELE-EVLREINEISSELPELREELEKlekevKELEELKEE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  994 LRAMEREAEQMGTELEKLRAALME---SQGQQQEERGQQEREVARLTQERGQAEADLALEKaAKAELEMRLQNaLNEQQA 1070
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIREleeRIEELKKEIEELEEKVKELKELKEKAEEYIKLSE-FYEEYLDELRE-IEKRLS 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1071 EFANLQEALSRALSEKEGKDQELSKLCEqeavqrmELKELLQTVEQLKAQLAKKEKEQQQSARgasgenasgmgtqseav 1150
Cdd:PRK03918   318 RLEEEINGIEERIKELEEKEERLEELKK-------KLKELEKRLEELEERHELYEEAKAKKEE----------------- 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1151 gkMEALRAKVSKLEQqcqqqqeeaDSLARSLESerafhverdraLETLQGQLEEKARELGysqaasasaqRELATLRAKA 1230
Cdd:PRK03918   374 --LERLKKRLTGLTP---------EKLEKELEE-----------LEKAKEEIEEEISKIT----------ARIGELKKEI 421

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1231 QDHSKAEEEWKAqvARGQQEAVrkGSLISSlEEEVSILNRQVLEKEGESKELKRLviaeSEKSQKLEERLRLLQMETASN 1310
Cdd:PRK03918   422 KELKKAIEELKK--AKGKCPVC--GRELTE-EHRKELLEEYTAELKRIEKELKEI----EEKERKLRKELRELEKVLKKE 492

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1311 SaraaerssalreEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKawqEKFFQKEQALSALQLEHTSTQALVSE 1390
Cdd:PRK03918   493 S------------ELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLK---EKLIKLKGEIKSLKKELEKLEELKKK 557

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1391 LLPAKHLCQQLQAEQVAAEKRHREELEQSkqaagglrteLMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSM 1470
Cdd:PRK03918   558 LAELEKKLDELEEELAELLKELEELGFES----------VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEE 627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1471 LKKAHGLLAEENRGLGERAN----LGRQFLEVELDQAREKYIQ---ELAAVRGDAEtRLAEMRQEVQSTTHELEvmtaky 1543
Cdd:PRK03918   628 LDKAFEELAETEKRLEELRKeleeLEKKYSEEEYEELREEYLElsrELAGLRAELE-ELEKRREEIKKTLEKLK------ 700

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1196773644 1544 egAKVKVLEERQRFQEERQKLTAQVEELSKKLADY 1578
Cdd:PRK03918   701 --EELEEREKAKKELEKLEKALERVEELREKVKKY 733
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
579-967 4.60e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.61  E-value: 4.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  579 RHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQ-QLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAAN 657
Cdd:COG4717     80 LKEAEEKEEEYAELQEELEELEEELEELEAELEElREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELR 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  658 EAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATER-EKVAQEKAQLQEQLWSL 736
Cdd:COG4717    160 ELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEElEELEEELEQLENELEAA 239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  737 EESLKITKGS----LEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETK 812
Cdd:COG4717    240 ALEERLKEARllllIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEE 319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  813 ALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSCQELRETKEKMAgiEAHSEL 892
Cdd:COG4717    320 ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAAL--EQAEEY 397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  893 QigQHQSELAQLHANLARALQQVQEK---------ENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLE 963
Cdd:COG4717    398 Q--ELKEELEELEEQLEELLGELEELlealdeeelEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELL 475


                   ....
gi 1196773644  964 LLKE 967
Cdd:COG4717    476 QELE 479
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1106-1687 5.46e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 5.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1106 ELKELLQTVEQLKAQLAKKEKEQQQSARGASgenasgmgtqsEAVGKMEALRAKVSKLEQQCQQQQEEADSLArSLESER 1185
Cdd:PRK03918   180 RLEKFIKRTENIEELIKEKEKELEEVLREIN-----------EISSELPELREELEKLEKEVKELEELKEEIE-ELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1186 AFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKgsliSSLEEEV 1265
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRL----SRLEEEI 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1266 SILNRQVLEKEGESKELKRLviaeSEKSQKLEERLRLLQmetasNSARAAERSSALREEVQSLREEVEKQraASENLRQE 1345
Cdd:PRK03918   324 NGIEERIKELEEKEERLEEL----KKKLKELEKRLEELE-----ERHELYEEAKAKKEELERLKKRLTGL--TPEKLEKE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1346 LASQAERAEELGQELKAWQEKffqkeqaLSALQLEHTSTQALVSELLPAKHLC------------QQLQAEQVAAEKRHR 1413
Cdd:PRK03918   393 LEELEKAKEEIEEEISKITAR-------IGELKKEIKELKKAIEELKKAKGKCpvcgrelteehrKELLEEYTAELKRIE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1414 EELEQSKQAAGGLRTELMRAQRELG---ELVPLRqKVAEQERAAQQ----LRAEKASY-AEQLSMLKKAHGLLAEENRGL 1485
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVLKkesELIKLK-ELAEQLKELEEklkkYNLEELEKkAEEYEKLKEKLIKLKGEIKSL 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1486 GERANLGRQF------LEVELDQAREkyiqELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKvKVLEERQRFQE 1559
Cdd:PRK03918   545 KKELEKLEELkkklaeLEKKLDELEE----ELAELLKELEELGFESVEELEERLKELEPFYNEYLELK-DAEKELEREEK 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1560 ERQKLTAQVEELSKKLAdydqaskvqqqklkafqaqggESQQEAQRLQTQLNELQVQLSQKEqaaehykvqmekakthYD 1639
Cdd:PRK03918   620 ELKKLEEELDKAFEELA---------------------ETEKRLEELRKELEELEKKYSEEE----------------YE 662

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1196773644 1640 AKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAE 1687
Cdd:PRK03918   663 ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAK 710
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 646-952 6.00e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.20  E-value: 6.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  646 LEILQQQlQAANEAQDSAQNSVTQAQR---EKAELSQKVEELHALIEA--AHQEQCEAQTQVAALEARLKAEQQKATERE 720
Cdd:pfam17380  275 LHIVQHQ-KAVSERQQQEKFEKMEQERlrqEKEEKAREVERRRKLEEAekARQAEMDRQAAIYAEQERMAMERERELERI 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  721 KVAQEKAQLqeqlwsleESLKITKGSLEEEKCRAAAALE-EHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQ 799
Cdd:pfam17380  354 RQEERKREL--------ERIRQEEIAMEISRMRELERLQmERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQI 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  800 LQQLAETHQAETKALRQELAKARTSNNMAEREVEllvKEVKTWRKRYEDSQQGETQYGLQEQLTTLKEEYEKSC--QELR 877
Cdd:pfam17380  426 RAEQEEARQREVRRLEEERAREMERVRLEEQERQ---QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKIleKELE 502

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644  878 ETKEKMagIEAHSELQIGQHQSELAQlHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRK 952
Cdd:pfam17380  503 ERKQAM--IEEERKRKLLEKEMEERQ-KAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERE 574
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
767-1209 7.03e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 7.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  767 EMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAEThQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRY 846
Cdd:COG4717     54 EADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAEL-QEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQ 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  847 EDSQqgetqygLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSElqigqhqsELAQLHANLARALQQV-QEKENRAQKL 925
Cdd:COG4717    133 ELEA-------LEAELAELPERLEELEERLEELRELEEELEELEA--------ELAELQEELEELLEQLsLATEEELQDL 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  926 ADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVeeqqgQQLCSTQAALRAMEREAEQMG 1005
Cdd:COG4717    198 AEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLL-----LLIAAALLALLGLGGSLLSLI 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1006 TELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANL---QEALSRA 1082
Cdd:COG4717    273 LTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELldrIEELQEL 352

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1083 LSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGE----NASGMGTQSEAVGKMEALRA 1158
Cdd:COG4717    353 LREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEeqleELLGELEELLEALDEEELEE 432

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1196773644 1159 KVSKLEQQCQQQQEEADSLARSLESERA--FHVERDRALETLQGQLEEKAREL 1209
Cdd:COG4717    433 ELEELEEELEELEEELEELREELAELEAelEQLEEDGELAELLQELEELKAEL 485
mukB PRK04863
chromosome partition protein MukB;
1174-1488 7.61e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.03  E-value: 7.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1174 ADSLARSLESERAFhverdRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQ---- 1249
Cdd:PRK04863   334 SDHLNLVQTALRQQ-----EKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQaldv 408

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1250 ---EAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQK---LEERLRLLQM-----ETASNSARAA--- 1315
Cdd:PRK04863   409 qqtRAIQYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEEllsLEQKLSVAQAahsqfEQAYQLVRKIage 488

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1316 -ERSSALREEVQSLReEVEKQRAASEN----------LRQELASQAeRAEELGQELKAWQEKFFQKEQALSALQLEHTST 1384
Cdd:PRK04863   489 vSRSEAWDVARELLR-RLREQRHLAEQlqqlrmrlseLEQRLRQQQ-RAERLLAEFCKRLGKNLDDEDELEQLQEELEAR 566

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1385 QALVSELLPAkhlcqqlQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQ---RELGELVP-----------LRQKVAEQ 1450
Cdd:PRK04863   567 LESLSESVSE-------ARERRMALRQQLEQLQARIQRLAARAPAWLAAQdalARLREQSGeefedsqdvteYMQQLLER 639

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1196773644 1451 ERAAQQ----LRAEKASYAEQLSMLKKAHGLLAEENRGLGER 1488
Cdd:PRK04863   640 ERELTVerdeLAARKQALDEEIERLSQPGGSEDPRLNALAER 681
PRK09039 PRK09039
peptidoglycan -binding protein;
585-721 7.78e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 47.27  E-value: 7.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  585 LSGSLKQKEKQLEEAARELD------ASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANE 658
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAeladllSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1196773644  659 AQDSAQNSVTQAQREKAELSQKVEEL-------HALIEAAHQEQCEAQTQVAALEARLK-AEQQKATEREK 721
Cdd:PRK09039   124 ELDSEKQVSARALAQVELLNQQIAALrrqlaalEAALDASEKRDRESQAKIADLGRRLNvALAQRVQELNR 194
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1346-1605 7.99e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 7.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1346 LASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVsellpakhlcQQLQAEQVAAEKRHREeleqskqaagg 1425
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL----------AALERRIAALARRIRA----------- 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1426 LRTELMRAQRELGELvplrqkVAEQERAAQQLRAEKASYAEQLSMLKKAhgllaeenrGLGERANLGRQFLEVELDQARE 1505
Cdd:COG4942     74 LEQELAALEAELAEL------EKEIAELRAELEAQKEELAELLRALYRL---------GRQPPLALLLSPEDFLDAVRRL 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1506 KYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADYDQASKVQ 1585
Cdd:COG4942    139 QYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL 218

                          250       260
                   ....*....|....*....|
gi 1196773644 1586 QQKLKAFQAQGGESQQEAQR 1605
Cdd:COG4942    219 QQEAEELEALIARLEAEAAA 238
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 239-935 8.89e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.86  E-value: 8.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  239 QTPQFQMRRLKKQLADERNNRDELELELAE--HRKLLTEKDAQISMMQQRIDRLALLNEKQAASPLEPRELEELRGKNES 316
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEkkHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  317 ltfRLHETLKQCQDLKTEKGQMDRKI----NQLSEENG----------DLSFKLREFASNLQQLQGALNELTEEHSKATQ 382
Cdd:pfam01576   83 ---RLEEEEERSQQLQNEKKKMQQHIqdleEQLDEEEAarqklqlekvTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  383 QWVEKQAHLEKELSTALQDKKcLEEKNEILqgkLSQLEERLAqlpespRQEKGEvlgdvLQLESLKQ----EAATLATNN 458
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSK-LKNKHEAM---ISDLEERLK------KEEKGR-----QELEKAKRklegESTDLQEQI 224

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  459 TQLQARVEMLENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQgAKLNAQVASLTAELTT 538
Cdd:pfam01576  225 AELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAAR-NKAEKQRRDLGEELEA 303

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  539 LSATLQQQDQELAGLKQqaqkkqaqlaqslqqqeqasqgLRHQVEQLSGSLKqkeKQLEEAARELDAS----RRDHAQQL 614
Cdd:pfam01576  304 LKTELEDTLDTTAAQQE----------------------LRSKREQEVTELK---KALEEETRSHEAQlqemRQKHTQAL 358

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  615 ATAAKAQETSLRERDAACQQLEALEKEKAAkleiLQQQLQAANEAQdsaqnsvTQAQREKAELSQKVEELHALIEAAHQE 694
Cdd:pfam01576  359 EELTEQLEQAKRNKANLEKAKQALESENAE----LQAELRTLQQAK-------QDSEHKRKKLEGQLQELQARLSESERQ 427

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  695 QCEAQTQVAALEARLKAEQQKATEREKVAqekAQLQEQLWSLEESLKITKGSLEEEKcRAAAALeehQHHISEMEAESRS 774
Cdd:pfam01576  428 RAELAEKLSKLQSELESVSSLLNEAEGKN---IKLSKDVSSLESQLQDTQELLQEET-RQKLNL---STRLRQLEDERNS 500

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  775 LAEQhkqerkeLEEEKAKRRGLGVQLQqlaeTHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQGET 854
Cdd:pfam01576  501 LQEQ-------LEEEEEAKRNVERQLS----TLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYD 569

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  855 QygLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSElQIGQHQSELAQLHANLA----RALQQVQEKENRAQKLADDLS 930
Cdd:pfam01576  570 K--LEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQK-KFDQMLAEEKAISARYAeerdRAEAEAREKETRALSLARALE 646


                   ....*
gi 1196773644  931 TLQEK 935
Cdd:pfam01576  647 EALEA 651
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1202-1731 1.06e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.81  E-value: 1.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1202 LEEKARElGYSQAASASAQRELATLRAKAQD-----HSKAEEEWKAQVARGQQEAVRK-GSLISSLEEEVSILNRQVLEK 1275
Cdd:pfam15921  283 LTEKASS-ARSQANSIQSQLEIIQEQARNQNsmymrQLSDLESTVSQLRSELREAKRMyEDKIEELEKQLVLANSELTEA 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1276 EGESKELKRLVIAESEKSQKL----EERLRLLQMETASNSaRAAERSSA-------LREEVQSLREEVEKQRAASENLRQ 1344
Cdd:pfam15921  362 RTERDQFSQESGNLDDQLQKLladlHKREKELSLEKEQNK-RLWDRDTGnsitidhLRRELDDRNMEVQRLEALLKAMKS 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1345 ELASQAER--------------AEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEK 1410
Cdd:pfam15921  441 ECQGQMERqmaaiqgkneslekVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1411 RHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEkasyAEQLSMLKKAHGLLAeeNRGLGERAN 1490
Cdd:pfam15921  521 KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQ----IENMTQLVGQHGRTA--GAMQVEKAQ 594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1491 LGRQFLEVELDqarekyIQELAAVRGDAETRLAEMRQEVQstthELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVE- 1569
Cdd:pfam15921  595 LEKEINDRRLE------LQEFKILKDKKDAKIRELEARVS----DLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKt 664

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1570 ---ELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEH-YKVQMEKAKtHYDAKKQQN 1645
Cdd:pfam15921  665 srnELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHaMKVAMGMQK-QITAKRGQI 743

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1646 QELQEQLQGLEQ-LQKENKE---LRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRELG-KFQVA 1720
Cdd:pfam15921  744 DALQSKIQFLEEaMTNANKEkhfLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASlQFAEC 823

                          570
                   ....*....|.
gi 1196773644 1721 SDALKSREPQA 1731
Cdd:pfam15921  824 QDIIQRQEQES 834
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 679-1419 1.17e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.41  E-value: 1.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  679 QKVEELHALIEAAHQEQCEAQTQVAalEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKcraaAAL 758
Cdd:pfam05483   42 QKLNFLPMLEQVANSGDCHYQEGLK--DSDFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENR----KII 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  759 EEHQHHISEMEAESRSLA---EQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELL 835
Cdd:pfam05483  116 EAQRKAIQELQFENEKVSlklEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKM 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  836 VKEVKTWRKRYEDSQQgetqyglqEQLTTLKEEYEKSCQELRETKEKMAGIEAHSEL---QIGQHQSELAQLHANLARAL 912
Cdd:pfam05483  196 ILAFEELRVQAENARL--------EMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLlliQITEKENKMKDLTFLLEESR 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  913 QQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASlELLKEPPKTRDRESEwVEEQQGQQLCSTQA 992
Cdd:pfam05483  268 DKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALE-EDLQIATKTICQLTE-EKEAQMEELNKAKA 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  993 ALRAMEREAEQMGTELEKLraaLMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEmRLQNALNEQQaEF 1072
Cdd:pfam05483  346 AHSFVVTEFEATTCSLEEL---LRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELE-ELKKILAEDE-KL 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1073 ANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENasgmgtqSEAVGK 1152
Cdd:pfam05483  421 LDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKN-------IELTAH 493

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1153 MEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQD 1232
Cdd:pfam05483  494 CDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEE 573

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1233 HSKAEEEwkaQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSA 1312
Cdd:pfam05483  574 NARSIEY---EVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQ 650

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1313 RAAERSSALREEV-------QSLREEVEKQRAASE---NLRQELASQAER-------------------AEELGQELKAW 1363
Cdd:pfam05483  651 KFEEIIDNYQKEIedkkiseEKLLEEVEKAKAIADeavKLQKEIDKRCQHkiaemvalmekhkhqydkiIEERDSELGLY 730

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1196773644 1364 QEKFFQKEQALSALQLEHTSTQAlvsELLPAKhlcQQLQAEQVAAEKRHREELEQS 1419
Cdd:pfam05483  731 KNKEQEQSSAKAALEIELSNIKA---ELLSLK---KQLEIEKEEKEKLKMEAKENT 780
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
606-739 1.28e-04

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 46.58  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  606 SRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKA---AKLEILQQQLQAANEAQdsAQNSVTQAQREKAElsqkve 682
Cdd:COG1566     83 AALAQAEAQLAAAEAQLARLEAELGAEAEIAAAEAQLAaaqAQLDLAQRELERYQALY--KKGAVSQQELDEAR------ 154

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1196773644  683 elhALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEES 739
Cdd:COG1566    155 ---AALDAAQAQLEAAQAQLAQAQAGLREEEELAAAQAQVAQAEAALAQAELNLART 208
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
590-716 1.40e-04

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 46.79  E-value: 1.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  590 KQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAAcqqleALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQ 669
Cdd:COG2268    219 ANREAEEAELEQEREIETARIAEAEAELAKKKAEERREAETA-----RAEAEAAYEIAEANAEREVQRQLEIAEREREIE 293

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1196773644  670 AQREKAELSQKVEElhalieAAHQEQCEAQTQVAALEARLKAEQQKA 716
Cdd:COG2268    294 LQEKEAEREEAELE------ADVRKPAEAEKQAAEAEAEAEAEAIRA 334
mukB PRK04863
chromosome partition protein MukB;
1305-1723 1.42e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 1.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1305 METASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFfQKEQALSALQLEHTST 1384
Cdd:PRK04863   275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKIERY 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1385 QALVSELLPAkhLCQQLQAEQVAAEKR--HREELEQSKQAAGGLRTELMRAQRELGELvplrQKVAEQERAAQQL--RAE 1460
Cdd:PRK04863   354 QADLEELEER--LEEQNEVVEEADEQQeeNEARAEAAEEEVDELKSQLADYQQALDVQ----QTRAIQYQQAVQAleRAK 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1461 KASYAEQLSmLKKAHGLLAEENRGLGERANlgrqflevELDQAREKYiqelaAVRGDAETRLAEMRQEVQSTTHELEVMT 1540
Cdd:PRK04863   428 QLCGLPDLT-ADNAEDWLEEFQAKEQEATE--------ELLSLEQKL-----SVAQAAHSQFEQAYQLVRKIAGEVSRSE 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1541 AKyegakvKVLEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQaqggESQQEAQRLQTQLNELQVQLSQK 1620
Cdd:PRK04863   494 AW------DVARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLA----EFCKRLGKNLDDEDELEQLQEEL 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1621 EQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLG----------QELQQAGLKTKEAEqtc 1690
Cdd:PRK04863   564 EARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLReqsgeefedsQDVTEYMQQLLERE--- 640

                          410       420       430
                   ....*....|....*....|....*....|...
gi 1196773644 1691 RHLTAQVRSLEAQVAHADQQLRELGKFQVASDA 1723
Cdd:PRK04863   641 RELTVERDELAARKQALDEEIERLSQPGGSEDP 673
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 247-787 1.61e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.04  E-value: 1.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  247 RLKKQLADERNNRDELELElAEHRKLLTEKDAQISMMqqrIDRLAllnekqaasplepRELEELRGKNESLTFRLHETLK 326
Cdd:pfam15921  378 QLQKLLADLHKREKELSLE-KEQNKRLWDRDTGNSIT---IDHLR-------------RELDDRNMEVQRLEALLKAMKS 440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  327 QCQdlktekGQMDRKINQLSEENGDLSfKLREFASNLQQLQGALNELTEEHSkATQQWVEKQAHLEKELSTALQDK-KCL 405
Cdd:pfam15921  441 ECQ------GQMERQMAAIQGKNESLE-KVSSLTAQLESTKEMLRKVVEELT-AKKMTLESSERTVSDLTASLQEKeRAI 512

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  406 EEKNEILQGKLSQLEERLAQLPESPRQEKgevlgdvlQLESLKQEAATLATNNTQLQARVEMLEnEQGQKEAQLLGERSH 485
Cdd:pfam15921  513 EATNAEITKLRSRVDLKLQELQHLKNEGD--------HLRNVQTECEALKLQMAEKDKVIEILR-QQIENMTQLVGQHGR 583

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  486 ----FEEEKQQLASLITNLQSSISNLSQAKEEleqaSQAQGAKLNAQVASLTAE-----------LTTLSATLQQQDQEL 550
Cdd:pfam15921  584 tagaMQVEKAQLEKEINDRRLELQEFKILKDK----KDAKIRELEARVSDLELEkvklvnagserLRAVKDIKQERDQLL 659

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  551 aglkQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERda 630
Cdd:pfam15921  660 ----NEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQ-- 733

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  631 acQQLEAlekeKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELhalieaahqeqceaqtqvaalearlk 710
Cdd:pfam15921  734 --KQITA----KRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTV-------------------------- 781

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1196773644  711 aeqqkATEREKVAQEKAQLQEQlwslEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELE 787
Cdd:pfam15921  782 -----ATEKNKMAGELEVLRSQ----ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1042-1724 1.65e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.89  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1042 QAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRME-LKELLQTVEQLKAQ 1120
Cdd:TIGR00618  151 QGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDtYHERKQVLEKELKH 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1121 LAKKEKEQQQS------ARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERD-- 1192
Cdd:TIGR00618  231 LREALQQTQQShayltqKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQaq 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1193 RALETLQGQLEEKARELGYSQAASASaqrelatlRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRqv 1272
Cdd:TIGR00618  311 RIHTELQSKMRSRAKLLMKRAAHVKQ--------QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQH-- 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1273 lekegeSKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERS------SALREEVQSLREEVEKQRAASENLRQEL 1346
Cdd:TIGR00618  381 ------IHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRdlqgqlAHAKKQQELQQRYAELCAAAITCTAQCE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1347 ASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL----LPAKHLCQQLQAEQVAA-------------- 1408
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELqeepCPLCGSCIHPNPARQDIdnpgpltrrmqrge 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1409 --EKRHREELEQSKQAAGGLRTELMR----AQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEN 1482
Cdd:TIGR00618  535 qtYAQLETSEEDVYHQLTSERKQRASlkeqMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQ 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1483 RGLGERAN--LGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRF--- 1557
Cdd:TIGR00618  615 HALLRKLQpeQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQlty 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1558 --------QEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQ-TQLNEL---QVQLSQKEQAAE 1625
Cdd:TIGR00618  695 wkemlaqcQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQArTVLKARteaHFNNNEEVTAAL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1626 HYKVQMEKAKTHYDAKKQQNQELQEQLQGLE-QLQKENKE----LRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSL 1700
Cdd:TIGR00618  775 QTGAELSHLAAEIQFFNRLREEDTHLLKTLEaEIGQEIPSdediLNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKY 854

                          730       740
                   ....*....|....*....|....
gi 1196773644 1701 EAQVAHADQQLRELGKFQVASDAL 1724
Cdd:TIGR00618  855 EECSKQLAQLTQEQAKIIQLSDKL 878
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
927-1364 1.75e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 1.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  927 DDLSTLQEKMAATSKEVARLEALVRKagEQQETASLELLKEPPKTRDRESEWVEEQQgqQLCSTQAALRAMEREAEQMGT 1006
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAELQEE--LEELEEELEELEAELEELREELEKLEKLL--QLLPLYQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1007 ELEKLRAALMESQGQQQEERGQQerevARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEK 1086
Cdd:COG4717    147 RLEELEERLEELRELEEELEELE----AELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1087 EGKDQELSKLceqeaVQRMELKELLQTVEQLKAQLAkkekeqqqSARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQ 1166
Cdd:COG4717    223 EELEEELEQL-----ENELEAAALEERLKEARLLLL--------IAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALL 289

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1167 CQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVAR 1246
Cdd:COG4717    290 FLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELE 369

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1247 GQQEAVRKGSLISSLEEEVSILN--RQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAA-----ERSS 1319
Cdd:COG4717    370 QEIAALLAEAGVEDEEELRAALEqaEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEEleeleEELE 449

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1196773644 1320 ALREEVQSLREEVEkQRAASENLRQELASQAERAEELGQELKAWQ 1364
Cdd:COG4717    450 ELREELAELEAELE-QLEEDGELAELLQELEELKAELRELAEEWA 493
HkD_SF cd22211
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ...
 44-165 1.95e-04

Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.


Pssm-ID: 411792  Cd Length: 145  Bit Score: 43.80  E-value: 1.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644   44 VNSLRVADLVEAVPQLQDCSVFIKIIDGIRGTEEGQQILQQPVP--------ERLDFVCSFLQKNR----KRPSSPECLV 111
Cdd:cd22211      8 INTFPLSSPVESLDDLSDGVVLAEILSQIDPSYFDSEWLESRDSsdnwvlklNNLKKLYRSLSKYYrevlGQQLSDLPLP 87

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1196773644  112 SMQKVME-GSELELAKIIMLLLYHSSMSSQNLRD---WEQFEYRIQAELAVILKFMLD 165
Cdd:cd22211     88 DLSAIARdGDEEEIVKLLELVLGAAVQCENKEEYiarIQQLDESTQAELMLIIQEVLE 145
DUF1633 pfam07794
Protein of unknown function (DUF1633); This family contains sequences derived from a group of ...
 583-777 2.03e-04

Protein of unknown function (DUF1633); This family contains sequences derived from a group of hypothetical proteins expressed by Arabidopsis thaliana. These sequences are highly similar and the region concerned is about 100 residues long.


Pssm-ID: 116408 [Multi-domain]  Cd Length: 698  Bit Score: 46.42  E-value: 2.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  583 EQLSGSLKQKEKQLEE---AARELDAS-RRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANE 658
Cdd:pfam07794  440 KQVGCSLRASAKEGEEgerAIREEDPHlGADQDREVRFGAEGIVPGIERLKIELSTSKDLEKGYAEKIGFMEMEFGGLEA 519

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  659 AQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAeqqKATEREKVAQEKAQLQEQLWSLEE 738
Cdd:pfam07794  520 DKQMARNQIHRLEEKKDELSKKVLDLTSIAQGAKKAVHDAKVELAAAYLKLLA---GIKDKWVAKKEFTVLEGQAAEVES 596

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1196773644  739 SL----KITKGS--LEEEKCRAAAALEEHQHHISEMEAESRSLAE 777
Cdd:pfam07794  597 NLalidQITKAAidLTLEKPRFQAEIDDLEARCKLKEVSDFTLSK 641
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 625-798 2.18e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.92  E-value: 2.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  625 LRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQT--QV 702
Cdd:COG1579     12 LQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNnkEY 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  703 AALE---ARLKAEQQKATEREKVAQEKA-QLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQ 778
Cdd:COG1579     92 EALQkeiESLKRRISDLEDEILELMERIeELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171

                          170       180
                   ....*....|....*....|.
gi 1196773644  779 HKQERKEL-EEEKAKRRGLGV 798
Cdd:COG1579    172 IPPELLALyERIRKRKNGLAV 192
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 245-547 2.40e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.59  E-value: 2.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  245 MRRLKKQLADERNNR---------DELELELAEHRKLLTEKDAQISMMQQRI----DRLALLNEKQAASPLEPRELE-EL 310
Cdd:PRK10929    81 SAELRQQLNNERDEPrsvppnmstDALEQEILQVSSQLLEKSRQAQQEQDRAreisDSLSQLPQQQTEARRQLNEIErRL 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  311 RGKNESLTfrlheTLKQCQD--LKTEKGQMDRKIN-----QLSEEN--------GDLSFKLREFASN-LQQLQGALNEL- 373
Cdd:PRK10929   161 QTLGTPNT-----PLAQAQLtaLQAESAALKALVDelelaQLSANNrqelarlrSELAKKRSQQLDAyLQALRNQLNSQr 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  374 ---TEEHSKATQQWVEKQAHLEKELSTALQdkkcleeKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQE 450
Cdd:PRK10929   236 qreAERALESTELLAEQSGDLPKSIVAQFK-------INRELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTLREQ 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  451 AATLATNNT---QLQARV----EMLENEQGQKE-AQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQAS-QAQ 521
Cdd:PRK10929   309 SQWLGVSNAlgeALRAQVarlpEMPKPQQLDTEmAQLRVQRLRYEDLLNKQPQLRQIRQADGQPLTAEQNRILDAQlRTQ 388

                          330       340       350
                   ....*....|....*....|....*....|
gi 1196773644  522 GAKLNAQVA---SLTAELTTLS-ATLQQQD 547
Cdd:PRK10929   389 RELLNSLLSggdTLILELTKLKvANSQLED 418
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1763-2018 2.66e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.32  E-value: 2.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1763 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGPA--PLESSLDSLGEPFLDSGRKTRSA-------------RRR 1827
Cdd:PHA03307   192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENEcplprpapitlptRIW 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1828 TTQIINITMTKKLDVEEPDSANSSfYSTRSAPASQAGLRATSSTQSLARLGSPDDGNSAllslpgyrpTTRSSTRRSQAG 1907
Cdd:PHA03307   271 EASGWNGPSSRPGPASSSSSPRER-SPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS---------TSSSSESSRGAA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1908 VSSGAPPGRNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlglatitdeemktgdpqETLRRASM 1987
Cdd:PHA03307   341 VSPGPSPSRS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARA 392

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1196773644 1988 Q---PGQIAEGAGITTRQQRKRVSSETHQGPGTP 2018
Cdd:PHA03307   393 AvagRARRRDATGRFPAGRPRPSPLDAGAASGAF 426
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1549-1743 2.74e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 2.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1549 KVLEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQL-SQKEQAAEHY 1627
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELeAQKEELAELL 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1628 KVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHA 1707
Cdd:COG4942    111 RALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAAL 190

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1196773644 1708 DQQLRELGKFQVASDALKSREPQAKPQLDLSIDSLD 1743
Cdd:COG4942    191 EALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1034-1511 2.84e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 2.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1034 ARLTQERGQAEADLALEKAAKAELEMRLQNAlnEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAvqrmELKELLQT 1113
Cdd:COG4717     91 AELQEELEELEEELEELEAELEELREELEKL--EKLLQLLPLYQELEALEAELAELPERLEELEERLE----ELRELEEE 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1114 VEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVgkmEALRAKVSKLEQQCQQQQEEADSLARSLESERAfhverdr 1193
Cdd:COG4717    165 LEELEAELAELQEELEELLEQLSLATEEELQDLAEEL---EELQQRLAELEEELEEAQEELEELEEELEQLEN------- 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1194 alETLQGQLEEKARELGYSQAASASaqreLATLRAKAQDHSKAEEEWKAQVArgqqeavrkgSLISSLEEEVSILNRQVL 1273
Cdd:COG4717    235 --ELEAAALEERLKEARLLLLIAAA----LLALLGLGGSLLSLILTIAGVLF----------LVLGLLALLFLLLAREKA 298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1274 EKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALrEEVQSLREEVEKQRAASENLRQELASQAERA 1353
Cdd:COG4717    299 SLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRI-EELQELLREAEELEEELQLEELEQEIAALLA 377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1354 EELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVaaekrhREELEQSKQAAGGLRTELMRA 1433
Cdd:COG4717    378 EAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEL------EEELEELEEELEELEEELEEL 451

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1196773644 1434 QRELGELVpLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGllaeenrglgeRANLGRQFLEVELDQAREKYIQEL 1511
Cdd:COG4717    452 REELAELE-AELEQLEEDGELAELLQELEELKAELRELAEEWA-----------ALKLALELLEEAREEYREERLPPV 517
mukB PRK04863
chromosome partition protein MukB;
858-1626 3.55e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.10  E-value: 3.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  858 LQEQLTTLKEEYEKSCQELRETKEKMAGIEahSELQIGQHQSELAQLHANLARALQQVQEKENRAQklaDDLSTLQEKMA 937
Cdd:PRK04863   291 LRRELYTSRRQLAAEQYRLVEMARELAELN--EAESDLEQDYQAASDHLNLVQTALRQQEKIERYQ---ADLEELEERLE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  938 ATSkevarleALVRKAGEQQETaslellkeppktRDRESEWVEEQQGQ---QLCSTQAALRAMEREAEQMGTELEKLRAA 1014
Cdd:PRK04863   366 EQN-------EVVEEADEQQEE------------NEARAEAAEEEVDElksQLADYQQALDVQQTRAIQYQQAVQALERA 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1015 lmesqgQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQAEFANLQEALSRALSEKEGKDQELS 1094
Cdd:PRK04863   427 ------KQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARE 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1095 KLCEQEavqrmELKELLQTVEQLKAQLA--KKEKEQQQSARGASGENASGMGTQSEAVGKMEALRAkvskleqqcqqqqe 1172
Cdd:PRK04863   501 LLRRLR-----EQRHLAEQLQQLRMRLSelEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQE-------------- 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1173 EADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAK---AQDHSKAEEEWKAQVARGQQ 1249
Cdd:PRK04863   562 ELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQsgeEFEDSQDVTEYMQQLLERER 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1250 EAVRKGSLISSLEEEVSILNRQVLEKEG-ESKELKRL-------VIAE-------------------------------- 1289
Cdd:PRK04863   642 ELTVERDELAARKQALDEEIERLSQPGGsEDPRLNALaerfggvLLSEiyddvsledapyfsalygparhaivvpdlsda 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1290 SEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQ-------------RAASENLRQELASQAERAEEL 1356
Cdd:PRK04863   722 AEQLAGLEDCPEDLYLIEGDPDSFDDSVFSVEELEKAVVVKIADRQwrysrfpevplfgRAAREKRIEQLRAEREELAER 801

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1357 GQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQ------AEQVAAEKRHREELEQSKQAAGGLRTEL 1430
Cdd:PRK04863   802 YATLSFDVQKLQRLHQAFSRFIGSHLAVAFEADPEAELRQLNRRRVeleralADHESQEQQQRSQLEQAKEGLSALNRLL 881

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1431 MRAQRELGELVPLR-QKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEnrglgeranlgrqflEVELDQAREKYIQ 1509
Cdd:PRK04863   882 PRLNLLADETLADRvEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSD---------------PEQFEQLKQDYQQ 946

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1510 elaavrgdAETRLAEMRQEVQSTTHELEVMTA-KYEGAkVKVLEE--------RQRFQEERQKLTAQVEELSKKLADYDQ 1580
Cdd:PRK04863   947 --------AQQTQRDAKQQAFALTEVVQRRAHfSYEDA-AEMLAKnsdlneklRQRLEQAEQERTRAREQLRQAQAQLAQ 1017

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*...
gi 1196773644 1581 ASKVQQQKLKAFQAQggesQQEAQRLQTQLNELQVQLSQ--KEQAAEH 1626
Cdd:PRK04863  1018 YNQVLASLKSSYDAK----RQMLQELKQELQDLGVPADSgaEERARAR 1061
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 581-792 3.77e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  581 QVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAA--NE 658
Cdd:COG4942     38 ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALyrLG 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  659 AQDS-----AQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEArlkaeqqkatEREKVAQEKAQLQEQL 733
Cdd:COG4942    118 RQPPlalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA----------ERAELEALLAELEEER 187

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1196773644  734 WSLEESLKITKGSLEeekcRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAK 792
Cdd:COG4942    188 AALEALKAERQKLLA----RLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 589-912 4.78e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 4.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  589 LKQKEKQLEEAAREL---DASRRDHAQQLAtAAKAQETSLRerdAACQQLEALEKEK-AAKLEILQQQLQAANEAQDSAQ 664
Cdd:COG3096    838 LAALRQRRSELERELaqhRAQEQQLRQQLD-QLKEQLQLLN---KLLPQANLLADETlADRLEELREELDAAQEAQAFIQ 913

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  665 ---NSVTQAQREKAELS---QKVEELHALIEAAHQEQCEAQTQVAALEarlkaeqQKATEREKVA-QEKAQLQEQLWSLE 737
Cdd:COG3096    914 qhgKALAQLEPLVAVLQsdpEQFEQLQADYLQAKEQQRRLKQQIFALS-------EVVQRRPHFSyEDAVGLLGENSDLN 986

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  738 ESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAE-THQAETKALRQ 816
Cdd:COG3096    987 EKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEeRARIRRDELHE 1066

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  817 ELAKARTSNNMAEREVELLVKEVKTWRKRYedSQQGETQYGLQEQLTTLKEEYeksCQELRetkekmagIEAHSELQIGQ 896
Cdd:COG3096   1067 ELSQNRSRRSQLEKQLTRCEAEMDSLQKRL--RKAERDYKQEREQVVQAKAGW---CAVLR--------LARDNDVERRL 1133

                          330
                   ....*....|....*.
gi 1196773644  897 HQSELAQLHANLARAL 912
Cdd:COG3096   1134 HRRELAYLSADELRSM 1149
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1313-1614 4.84e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 4.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1313 RAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELL 1392
Cdd:PRK03918   162 NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1393 PAKhlcqqlqaEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLK 1472
Cdd:PRK03918   242 ELE--------KELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1473 KAHGLLAEENRGLGERANlgrqflEVELDQAREKYIQELaavrgdaetrlaemRQEVQSTTHELEVMTAKYEGAKVKvLE 1552
Cdd:PRK03918   314 KRLSRLEEEINGIEERIK------ELEEKEERLEELKKK--------------LKELEKRLEELEERHELYEEAKAK-KE 372

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1196773644 1553 ERQRFQEERQKLTaqVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQ 1614
Cdd:PRK03918   373 ELERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELK 432
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1261-1713 5.06e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 45.55  E-value: 5.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1261 LEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASE 1340
Cdd:pfam01576  101 MQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSK 180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1341 NLRQELASQAERAEELGQELKAWQEKffqkEQALSALQLEHTSTQALVSELlpakhlcqQLQAEQVAAEKRHREELEQSK 1420
Cdd:pfam01576  181 LKNKHEAMISDLEERLKKEEKGRQEL----EKAKRKLEGESTDLQEQIAEL--------QAQIAELRAQLAKKEEELQAA 248

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1421 QA----AGGLRTELMRAQRELGELVPLRQKVAEQERAAQQlRAEKasyaeqlsmlkkahgllaeENRGLGERANLGRQFL 1496
Cdd:pfam01576  249 LArleeETAQKNNALKKIRELEAQISELQEDLESERAARN-KAEK-------------------QRRDLGEELEALKTEL 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1497 EVELD------QAREKYIQELAAVR--GDAETR-----LAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQK 1563
Cdd:pfam01576  309 EDTLDttaaqqELRSKREQEVTELKkaLEEETRsheaqLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAE 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1564 LTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKakthydAKKQ 1643
Cdd:pfam01576  389 LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIK------LSKD 462

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1196773644 1644 QNQELQEQLQGLEQLQKENKELRAEAERLGQ-ELQQAGLKTK--EAEQTCRHLTAQVRSLEAQVAHADQQLRE 1713
Cdd:pfam01576  463 VSSLESQLQDTQELLQEETRQKLNLSTRLRQlEDERNSLQEQleEEEEAKRNVERQLSTLQAQLSDMKKKLEE 535
mukB PRK04863
chromosome partition protein MukB;
607-1017 5.23e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.33  E-value: 5.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  607 RRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLE---ILQQQLQAANEAQDSAQNSVTQAQREKaELSQKVEE 683
Cdd:PRK04863   281 RRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEaesDLEQDYQAASDHLNLVQTALRQQEKIE-RYQADLEE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  684 LHALIEAAHQEQCEAQTQVAALEARLKAEQQkaterekvaqEKAQLQEQLWSLEESLKI--TKGSLEEEkcrAAAALEEH 761
Cdd:PRK04863   360 LEERLEEQNEVVEEADEQQEENEARAEAAEE----------EVDELKSQLADYQQALDVqqTRAIQYQQ---AVQALERA 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  762 QHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALrqelAKARTSNNMAEREVellvkevkT 841
Cdd:PRK04863   427 KQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAY----QLVRKIAGEVSRSE--------A 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  842 WRKRYEDSQQGETQYGLQEQLTtlkeeyekscqelretkekmagieahselQIGQHQSELAQLHANLARALQQVQEKENR 921
Cdd:PRK04863   495 WDVARELLRRLREQRHLAEQLQ-----------------------------QLRMRLSELEQRLRQQQRAERLLAEFCKR 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  922 AQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQET--ASLELLK-EPPKTRDRESEWVEEQQG-QQLCS-TQAALRA 996
Cdd:PRK04863   546 LGKNLDDEDELEQLQEELEARLESLSESVSEARERRMAlrQQLEQLQaRIQRLAARAPAWLAAQDAlARLREqSGEEFED 625

                          410       420
                   ....*....|....*....|.
gi 1196773644  997 MEREAEQMGTELEKLRAALME 1017
Cdd:PRK04863   626 SQDVTEYMQQLLERERELTVE 646
PRK11281 PRK11281
mechanosensitive channel MscK;
257-550 5.38e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 45.29  E-value: 5.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  257 NNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAASPLEPRELEELrgknESltfRLHETLKQCQDLKtekg 336
Cdd:PRK11281    73 DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQL----ES---RLAQTLDQLQNAQ---- 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  337 qmdrkiNQLSEENGDLsfklrefaSNLQ-QLQGALNELTeEHSKATQQwvekqahLEKELSTALQDKKCL--EEKNEiLQ 413
Cdd:PRK11281   142 ------NDLAEYNSQL--------VSLQtQPERAQAALY-ANSQRLQQ-------IRNLLKGGKVGGKALrpSQRVL-LQ 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  414 GKLSQLEerlaqlpesprqekgevlgdvLQLESLKQEAAtlatNNTQLQarvemlenEQGQKEAQLLGERShfeeekQQL 493
Cdd:PRK11281   199 AEQALLN---------------------AQNDLQRKSLE----GNTQLQ--------DLLQKQRDYLTARI------QRL 239

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1196773644  494 ASLITNLQSSIS--NLSQAKEELEQASQAQGA---KLNAQVASLTAELTTLSATLQQQDQEL 550
Cdd:PRK11281   240 EHQLQLLQEAINskRLTLSEKTVQEAQSQDEAariQANPLVAQELEINLQLSQRLLKATEKL 301
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 998-1673 5.66e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.34  E-value: 5.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  998 EREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEMRLQNALNEQQA---EFAN 1074
Cdd:TIGR00618  195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRArieELRA 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1075 LQEALSRALSEKEGKDQELSKLCEQEAVQRMElKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEavgkmE 1154
Cdd:TIGR00618  275 QEAVLEETQERINRARKAAPLAAHIKAVTQIE-QQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLL-----Q 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1155 ALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRaLETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHS 1234
Cdd:TIGR00618  349 TLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ-KTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLA 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1235 KAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNR---QVLEKEGESKELKRLVIAESEKSQKLEERLRLLQMETA--- 1308
Cdd:TIGR00618  428 HAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQEsaqSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCplc 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1309 ------SNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHT 1382
Cdd:TIGR00618  508 gscihpNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIP 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1383 STQALVSELLPakHLCQQLQAEQVAAEKRHREELEQSKQAAGgLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKA 1462
Cdd:TIGR00618  588 NLQNITVRLQD--LTEKLSEAEDMLACEQHALLRKLQPEQDL-QDVRLHLQQCSQELALKLTALHALQLTLTQERVREHA 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1463 SYAEQLSMLKKAHGLLAE-ENRGLGERANLGRQFLE--VELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVM 1539
Cdd:TIGR00618  665 LSIRVLPKELLASRQLALqKMQSEKEQLTYWKEMLAqcQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQS 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1540 TAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQE-AQRLQTQLNELQVQLS 1618
Cdd:TIGR00618  745 LKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEiGQEIPSDEDILNLQCE 824

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1619 QKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLG 1673
Cdd:TIGR00618  825 TLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLN 879
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 498-728 5.88e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 5.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  498 TNLQSSISNLSQAKEELEQAsQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGlkqqaqkkqaqlaqslqqqeqasqg 577
Cdd:COG3883     16 PQIQAKQKELSELQAELEAA-QAELDALQAELEELNEEYNELQAELEALQAEIDK------------------------- 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  578 LRHQVEQLSGSLKQKEKQLEEAARELDASRR------------------DHAQQLATAAKAQETSLRERDAACQQLEALE 639
Cdd:COG3883     70 LQAEIAEAEAEIEERREELGERARALYRSGGsvsyldvllgsesfsdflDRLSALSKIADADADLLEELKADKAELEAKK 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  640 KEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATER 719
Cdd:COG3883    150 AELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229


                   ....*....
gi 1196773644  720 EKVAQEKAQ 728
Cdd:COG3883    230 AAAAAAAAA 238
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 238-886 6.06e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.96  E-value: 6.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  238 LQTPQFQMRRLKKQLADERNNRDELELELAEHRKLltekdaqismmQQRIDRlallNEKQAASPLEPRELEELRGKNESL 317
Cdd:TIGR00618  248 KREAQEEQLKKQQLLKQLRARIEELRAQEAVLEET-----------QERINR----ARKAAPLAAHIKAVTQIEQQAQRI 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  318 TFRLHETlkqcqdlKTEKGQMDRKINQLSEENGDLSFKLRefasNLQQLQGALNELTEEHSKAT--QQWVEKQAHLEKEL 395
Cdd:TIGR00618  313 HTELQSK-------MRSRAKLLMKRAAHVKQQSSIEEQRR----LLQTLHSQEIHIRDAHEVATsiREISCQQHTLTQHI 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  396 STALQDKKCLEEKNEILQGKLSQLEERLAQLpESPRQEKGEVLGDVLQLESLKQEAATLAtnnTQLQARVEMLENEQGQK 475
Cdd:TIGR00618  382 HTLQQQKTTLTQKLQSLCKELDILQREQATI-DTRTSAFRDLQGQLAHAKKQQELQQRYA---ELCAAAITCTAQCEKLE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  476 EAQLLGERSHFEEEKQQLASLitnlqssiSNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQqdqelAGLKQ 555
Cdd:TIGR00618  458 KIHLQESAQSLKEREQQLQTK--------EQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQD-----IDNPG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  556 QAQKKQAQLAQSLQQQEQASQGLRHQVEqlsgSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQL 635
Cdd:TIGR00618  525 PLTRRMQRGEQTYAQLETSEEDVYHQLT----SERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLT 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  636 EALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAE--- 712
Cdd:TIGR00618  601 EKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASrql 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  713 ---------QQKATEREKVAQEKAQLQEQLWSLEESLKITK---GSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHK 780
Cdd:TIGR00618  681 alqkmqsekEQLTYWKEMLAQCQTLLRELETHIEEYDREFNeieNASSSLGSDLAAREDALNQSLKELMHQARTVLKART 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  781 QERKELEEEKAKRRGLGVQLQQLA---ETHQAETKALRQELA--KARTSNNMAEREVELLVKEVKTWRKRYEDSQQGETQ 855
Cdd:TIGR00618  761 EAHFNNNEEVTAALQTGAELSHLAaeiQFFNRLREEDTHLLKtlEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEK 840

                          650       660       670
                   ....*....|....*....|....*....|.
gi 1196773644  856 YGLQEQLTTLKEEYEKSCQELRETKEKMAGI 886
Cdd:TIGR00618  841 SATLGEITHQLLKYEECSKQLAQLTQEQAKI 871
mukB PRK04863
chromosome partition protein MukB;
1059-1736 6.46e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.95  E-value: 6.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1059 MRLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAK-----KEKEQQQSAR 1133
Cdd:PRK04863   275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLvqtalRQQEKIERYQ 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1134 GASGENASGMGTQSEAVgkmEALRAKVSKLEQQCQQQQEEADSLARSL-ESERAFHVERDRALETLQG-QLEEKAREL-G 1210
Cdd:PRK04863   355 ADLEELEERLEEQNEVV---EEADEQQEENEARAEAAEEEVDELKSQLaDYQQALDVQQTRAIQYQQAvQALERAKQLcG 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1211 YSQAASASAQRELATLRAKAQDHSKAEEEWK-----AQVARGQQEAVRkgSLISSLEEEVSILN--RQVLEKEGESKELK 1283
Cdd:PRK04863   432 LPDLTADNAEDWLEEFQAKEQEATEELLSLEqklsvAQAAHSQFEQAY--QLVRKIAGEVSRSEawDVARELLRRLREQR 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1284 RLVIAESEKSQKLEE-RLRLLQMETASNSARAAERSSALREEVQSLREEV-EKQRAASENLRQELASQAERAEELGQELK 1361
Cdd:PRK04863   510 HLAEQLQQLRMRLSElEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLqEELEARLESLSESVSEARERRMALRQQLE 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1362 AWQEKFFQKEQ----------ALSALQlEHTSTQALVSELLPAkhlCQQLQAEQVAAEKRHREELEQSK----------- 1420
Cdd:PRK04863   590 QLQARIQRLAArapawlaaqdALARLR-EQSGEEFEDSQDVTE---YMQQLLERERELTVERDELAARKqaldeeierls 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1421 QAAGGLRTELMR-AQRELGELV--------------------PLRQK--VAEQERAAQQLRA------------------ 1459
Cdd:PRK04863   666 QPGGSEDPRLNAlAERFGGVLLseiyddvsledapyfsalygPARHAivVPDLSDAAEQLAGledcpedlyliegdpdsf 745

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1460 -EKASYAEQLsmlkkAHGLLAEENrglgERANLGRQFLEVEL--DQAREKYIQELAAVRGDAETRLAEMR---QEVQSTT 1533
Cdd:PRK04863   746 dDSVFSVEEL-----EKAVVVKIA----DRQWRYSRFPEVPLfgRAAREKRIEQLRAEREELAERYATLSfdvQKLQRLH 816

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1534 HELEVMTAKYEGAKVKVLEErqrfqEERQKLTAQVEELSKKLADYDqaSKVQQQKLKAFQAQggESQQEAQRLQTQLNEL 1613
Cdd:PRK04863   817 QAFSRFIGSHLAVAFEADPE-----AELRQLNRRRVELERALADHE--SQEQQQRSQLEQAK--EGLSALNRLLPRLNLL 887

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1614 QVQLSQKEqaAEHYKVQMEKAKthyDAKKQQNQELQEqlqgLEQLQKENKELRAEAE---RLGQELQQAGLKTKEAEQTC 1690
Cdd:PRK04863   888 ADETLADR--VEEIREQLDEAE---EAKRFVQQHGNA----LAQLEPIVSVLQSDPEqfeQLKQDYQQAQQTQRDAKQQA 958

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*.
gi 1196773644 1691 RHLTaQVRSLEAQVAHADQQlRELGKFQVASDALKSREPQAKPQLD 1736
Cdd:PRK04863   959 FALT-EVVQRRAHFSYEDAA-EMLAKNSDLNEKLRQRLEQAEQERT 1002
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1177-1392 6.78e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 6.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1177 LARSLESERAfhvERDRALETLQGQLEEKARELgysqaasASAQRELATLRAKAQDHSKAEEewkAQVARGQQEAVRkgS 1256
Cdd:COG3206    162 LEQNLELRRE---EARKALEFLEEQLPELRKEL-------EEAEAALEEFRQKNGLVDLSEE---AKLLLQQLSELE--S 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1257 LISSLEEEVSILNRQV--LEKEGESKELKRLVIAESEKSQKLEERLRLLQMETASNSARAAERSS---ALREEVQSLREE 1331
Cdd:COG3206    227 QLAEARAELAEAEARLaaLRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPdviALRAQIAALRAQ 306

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1332 VEKQ-RAASENLRQELASQAERAEELGQELKAWQEKFF---QKEQALSALQLEHTSTQALVSELL 1392
Cdd:COG3206    307 LQQEaQRILASLEAELEALQAREASLQAQLAQLEARLAelpELEAELRRLEREVEVARELYESLL 371
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 646-741 7.11e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 44.33  E-value: 7.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  646 LEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAAL-EARLKAEQ---QKATEREK 721
Cdd:TIGR04320  256 LAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTaQNNLATAQaalANAEARLA 335

                           90       100
                   ....*....|....*....|.
gi 1196773644  722 VAQEK-AQLQEQLWSLEESLK 741
Cdd:TIGR04320  336 KAKEAlANLNADLAKKQAALD 356
PRK09039 PRK09039
peptidoglycan -binding protein;
1443-1628 7.53e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.19  E-value: 7.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1443 LRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEenrglgERANLGRQFLEVELDQAR-EKYIQELAAVRGDAETR 1521
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQD------SVANLRASLSAAEAERSRlQALLAELAGAGAAAEGR 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1522 LAEMRQEVqstthelevmtakyegAKVKVLEERQRFQEERqkLTAQVEELSKKLADYDQAskvqqqkLKAFQAQGGESQQ 1601
Cdd:PRK09039   118 AGELAQEL----------------DSEKQVSARALAQVEL--LNQQIAALRRQLAALEAA-------LDASEKRDRESQA 172

                          170       180
                   ....*....|....*....|....*..
gi 1196773644 1602 EAQRLQTQLNelqVQLSQKEQAAEHYK 1628
Cdd:PRK09039   173 KIADLGRRLN---VALAQRVQELNRYR 196
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
 619-822 8.28e-04

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 44.55  E-value: 8.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  619 KAQETSLRERDAACQQLEA----LEKEKAAKLEILQQQLQA-ANEAQDSAQNSVTQAQREKAELSQKVEELH-------A 686
Cdd:PRK05035   439 RAIEQEKKKAEEAKARFEArqarLEREKAAREARHKKAAEArAAKDKDAVAAALARVKAKKAAATQPIVIKAgarpdnsA 518

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  687 LIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKIT---KGSLEEEKCRAAAALEEHQh 763
Cdd:PRK05035   519 VIAAREARKAQARARQAEKQAAAAADPKKAAVAAAIARAKAKKAAQQAANAEAEEEVdpkKAAVAAAIARAKAKKAAQQ- 597

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  764 hISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKA-LRQELAKAR 822
Cdd:PRK05035   598 -AASAEPEEQVAEVDPKKAAVAAAIARAKAKKAEQQANAEPEEPVDPRKAaVAAAIARAK 656
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 317-552 8.36e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  317 LTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQwvekQAHLEKELS 396
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE----LAALEAELA 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  397 TalqdkkcLEEKNEILQGKLSQLEERLA-QLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLEnEQGQK 475
Cdd:COG4942     87 E-------LEKEIAELRAELEAQKEELAeLLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE-ELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  476 EAQLLGERSHFEEEKQQLASLITNLQssisnlsQAKEELEQASQAQG---AKLNAQVASLTAELTTLSATLQQQDQELAG 552
Cdd:COG4942    159 LAELAALRAELEAERAELEALLAELE-------EERAALEALKAERQkllARLEKELAELAAELAELQQEAEELEALIAR 231
COG3899 COG3899
Predicted ATPase [General function prediction only];
899-1471 9.02e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 44.46  E-value: 9.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  899 SELAQLHANLARALQQV--QEKENRAQKLAD--DLSTLQEKMAATSKEVARlEALVRKAGEQQE---TASLELLKEPPKT 971
Cdd:COG3899    663 EERRALHRRIARALEARgpEPLEERLFELAHhlNRAGERDRAARLLLRAAR-RALARGAYAEALrylERALELLPPDPEE 741

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  972 RDRESewVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEK 1051
Cdd:COG3899    742 EYRLA--LLLELAEALYLAGRFEEAEALLERALAARALAALAALRHGNPPASARAYANLGLLLLGDYEEAYEFGELALAL 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1052 AAKAELEMRLQNALNeQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQS 1131
Cdd:COG3899    820 AERLGDRRLEARALF-NLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLA 898

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1132 ARGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGY 1211
Cdd:COG3899    899 AAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAA 978

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1212 SQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESE 1291
Cdd:COG3899    979 AAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAA 1058

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1292 KSQKLEERLRLLQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELkAWQEKFFQKE 1371
Cdd:COG3899   1059 AAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAA-AARAAAALLL 1137

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1372 QALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQE 1451
Cdd:COG3899   1138 LAAALALALAALLLLAALLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAALLALALLAL 1217

                          570       580
                   ....*....|....*....|
gi 1196773644 1452 RAAQQLRAEKASYAEQLSML 1471
Cdd:COG3899   1218 EAAALLLLLLLAALALAAAL 1237
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 578-822 1.27e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.17  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  578 LRHQVEQLSGSLKQKEKQLEEAARELD---ASRRDHAQQLATAAKAQETSLRERDAACQQLEALE---KEKAAKLEILQQ 651
Cdd:COG3096    862 LRQQLDQLKEQLQLLNKLLPQANLLADetlADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVavlQSDPEQFEQLQA 941

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  652 QLQAANEAQdsaqnsvTQAQREKAELSQKVEELHAL-IEAAHQEQCEAQTQVAALEARL-KAEQQKATEREKVAQEKAQL 729
Cdd:COG3096    942 DYLQAKEQQ-------RRLKQQIFALSEVVQRRPHFsYEDAVGLLGENSDLNEKLRARLeQAEEARREAREQLRQAQAQY 1014

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  730 QE--QLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESR-----SLAEQHKQERKELEEEKAKRRGLGVQLQQ 802
Cdd:COG3096   1015 SQynQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEERARIRrdelhEELSQNRSRRSQLEKQLTRCEAEMDSLQK 1094

                          250       260
                   ....*....|....*....|..
gi 1196773644  803 LAETHQAETKALRQEL--AKAR 822
Cdd:COG3096   1095 RLRKAERDYKQEREQVvqAKAG 1116
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1502-1710 1.29e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1502 QAREKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADYDQA 1581
Cdd:COG4942     37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRL 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1582 SKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKE 1661
Cdd:COG4942    117 GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAE 196

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1196773644 1662 NKELRAEAERLGQELQQAGLKTKEAEQTcrhLTAQVRSLEAQVAHADQQ 1710
Cdd:COG4942    197 RQKLLARLEKELAELAAELAELQQEAEE---LEALIARLEAEAAAAAER 242
46 PHA02562
endonuclease subunit; Provisional
 715-948 1.38e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.85  E-value: 1.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  715 KATEREkVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQhhisEMEAESRSLAEQHKQERKELEEEKAKrr 794
Cdd:PHA02562   173 KDKIRE-LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQ----NKYDELVEEAKTIKAEIEELTDELLN-- 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  795 glgvqLQQLAETHQAETKALRQELAKARTsnnmaerEVELLVKEVKTWRKRYE---DSQQGETQYGLQEQLTTLKEEYEK 871
Cdd:PHA02562   246 -----LVMDIEDPSAALNKLNTAAAKIKS-------KIEQFQKVIKMYEKGGVcptCTQQISEGPDRITKIKDKLKELQH 313

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1196773644  872 SCQELRETKEKMAGIEAhselQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEA 948
Cdd:PHA02562   314 SLEKLDTAIDELEEIMD----EFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
611-864 1.48e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  611 AQQLATAAKAQETSLRERDAAcQQLEALEKEkaakLEILQQQLQAANEAQDS--AQNSVTQAQREKAELSQKVEELHALI 688
Cdd:COG3206    154 ANALAEAYLEQNLELRREEAR-KALEFLEEQ----LPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQL 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  689 EAAHQEQCEAQTQVAALEARLKAEQQKATEREKvAQEKAQLQEQLWSLEeslkitkgsleeekcraaaaleehqhhiSEM 768
Cdd:COG3206    229 AEARAELAEAEARLAALRAQLGSGPDALPELLQ-SPVIQQLRAQLAELE----------------------------AEL 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  769 EAESRSLAEQH------KQERKELEEEKAKR-RGLGVQLQQLAETHQAETKALRQELAKART-SNNMAEREVEL--LVKE 838
Cdd:COG3206    280 AELSARYTPNHpdvialRAQIAALRAQLQQEaQRILASLEAELEALQAREASLQAQLAQLEArLAELPELEAELrrLERE 359

                          250       260
                   ....*....|....*....|....*.
gi 1196773644  839 VKTWRKRYEDSQQGETQYGLQEQLTT 864
Cdd:COG3206    360 VEVARELYESLLQRLEEARLAEALTV 385
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1268-1714 1.61e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.47  E-value: 1.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1268 LNRQVLEKEGESKELKRLVIAESEKSQKLEERLRllqmETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELA 1347
Cdd:TIGR04523  101 LNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKK----ENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELN 176

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1348 SQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQ----------AEQVAAEKRHREELE 1417
Cdd:TIGR04523  177 LLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKdniekkqqeiNEKTTEISNTQTQLN 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1418 QSKQAAGGLRTELMRAQRELGELvplRQKVAEQERAAQQLRAEkasyaeqLSMLK--KAHGLLAEENRGLGERANLGRQf 1495
Cdd:TIGR04523  257 QLKDEQNKIKKQLSEKQKELEQN---NKKIKELEKQLNQLKSE-------ISDLNnqKEQDWNKELKSELKNQEKKLEE- 325

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1496 LEVELDQArEKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEgakvKVLEERQRFQEERQKLTAQVEELSKKL 1575
Cdd:TIGR04523  326 IQNQISQN-NKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNLESQINDLESKI 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1576 ADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQNQELQEQ---- 1651
Cdd:TIGR04523  401 QNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSinki 480

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1196773644 1652 LQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLREL 1714
Cdd:TIGR04523  481 KQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDL 543
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 238-887 1.68e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 43.66  E-value: 1.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  238 LQTPQFQMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAasplepRELEELRGKNESL 317
Cdd:pfam10174   69 NQHLQLTIQALQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQA------KELFLLRKTLEEM 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  318 TFRLhETLKQ--------CQDLkTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKatqqwVEKQA 389
Cdd:pfam10174  143 ELRI-ETQKQtlgardesIKKL-LEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIH-----LREEL 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  390 HLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAATLATNNTQLQARVEMLE 469
Cdd:pfam10174  216 HRRNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLK 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  470 NEQGQKEAQLLGERSHFEEekqqlaslITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATL---QQQ 546
Cdd:pfam10174  296 QELSKKESELLALQTKLET--------LTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLnkkTKQ 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  547 DQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEE-----AARELDASRRDHAqqLATAAKAQ 621
Cdd:pfam10174  368 LQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGlkervKSLQTDSSNTDTA--LTTLEEAL 445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  622 ETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEEL--HALIEAAHQEQCEAQ 699
Cdd:pfam10174  446 SEKERIIERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLasSGLKKDSKLKSLEIA 525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  700 TQVAALEA-RLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKgsleEEKCRAAAALEEHQHHISEMEAEsrslaeQ 778
Cdd:pfam10174  526 VEQKKEECsKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVARYK----EESGKAQAEVERLLGILREVENE------K 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  779 HKQERKELEEEKAKRRGLGVQlqqlaETHQAETKALRQElakartsnnMAEREVELLVKEVKTWRKRYEDSQQgetqygl 858
Cdd:pfam10174  596 NDKDKKIAELESLTLRQMKEQ-----NKKVANIKHGQQE---------MKKKGAQLLEEARRREDNLADNSQQ------- 654

                          650       660
                   ....*....|....*....|....*....
gi 1196773644  859 qEQLTTLKEEYEKSCQELRETKEKMAGIE 887
Cdd:pfam10174  655 -LQLEELMGALEKTRQELDATKARLSSTQ 682
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 641-792 1.69e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 1.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  641 EKAAKLEILQQ---QLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKAT 717
Cdd:COG1579      4 EDLRALLDLQEldsELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLG 83

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644  718 EREKVAQEKAQLQEqlwslEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAK 792
Cdd:COG1579     84 NVRNNKEYEALQKE-----IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAE 153
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
249-426 1.70e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  249 KKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLALLNEKQAA----SPLEpRELEELRGKNESLT---FRL 321
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDeidvASAE-REIAELEAELERLDassDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  322 HETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEKELSTALQD 401
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVEREL 767

                          170       180
                   ....*....|....*....|....*
gi 1196773644  402 KKCLEEKNEILQGKLSQLEERLAQL 426
Cdd:COG4913    768 RENLEERIDALRARLNRAEEELERA 792
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
900-1346 1.72e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  900 ELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWV 979
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  980 EEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALEKAAKAELEM 1059
Cdd:COG4717    155 LEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEN 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1060 RLQNALNEQQAEFANLQEALSRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGEN 1139
Cdd:COG4717    235 ELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALE 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1140 AsgmgtqseavGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASa 1219
Cdd:COG4717    315 E----------LEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVED- 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1220 qreLATLRAKAQDHSKAEE-EWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEE 1298
Cdd:COG4717    384 ---EEELRAALEQAEEYQElKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEA 460

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 1196773644 1299 RLRllQMETASNSARAAERSSALREEVQSLREEVEKQRAASENLRQEL 1346
Cdd:COG4717    461 ELE--QLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAR 506
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 236-957 1.73e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.50  E-value: 1.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  236 DILQTPQF--QMRRLKKQLADERNNRDELELELaehRKLLTEKDAQISMMQQRIDRLALLNEKQAASPLEPRELEELRGK 313
Cdd:TIGR00606  177 EIFSATRYikALETLRQVRQTQGQKVQEHQMEL---KYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNR 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  314 NEsltfRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFasnLQQLQGALNELTEEHSKATQQWVEKQAHLEK 393
Cdd:TIGR00606  254 LK----EIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKV---FQGTDEQLNDLYHNHQRTVREKERELVDCQR 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  394 ELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPESPRQEKGEVLGDVLQLESLKQEAAtlATNNTQLQARVEMLENEQg 473
Cdd:TIGR00606  327 ELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERG--PFSERQIKNFHTLVIERQ- 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  474 qkeaqllgershfEEEKQQLASLITNLQSSISNLSQAKEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGL 553
Cdd:TIGR00606  404 -------------EDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSS 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  554 KQQAQKKQAQLAQSLQQQEQASqglrhqvEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSlrerdaacQ 633
Cdd:TIGR00606  471 DRILELDQELRKAERELSKAEK-------NSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTR--------T 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  634 QLEALEKEKAAKleilQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEarlkaeq 713
Cdd:TIGR00606  536 QMEMLTKDKMDK----DEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLE------- 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  714 qkaTEREKVAQEKAQLQEQLWSLEESLKITKGSLEEE--------------KCRA--AAALEEHQHHISEMEAESRS--- 774
Cdd:TIGR00606  605 ---QNKNHINNELESKEEQLSSYEDKLFDVCGSQDEEsdlerlkeeiekssKQRAmlAGATAVYSQFITQLTDENQSccp 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  775 LAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYE--DSQQG 852
Cdd:TIGR00606  682 VCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQkvNRDIQ 761

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  853 ETQYGLQEQLTTL-----KEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSEL--AQLHANLARALQQVQEKENRAQKL 925
Cdd:TIGR00606  762 RLKNDIEEQETLLgtimpEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLqgSDLDRTVQQVNQEKQEKQHELDTV 841

                          730       740       750
                   ....*....|....*....|....*....|..
gi 1196773644  926 ADDLSTLQEKMAATSKEVARLEALVRKAGEQQ 957
Cdd:TIGR00606  842 VSKIELNRKLIQDQQEQIQHLKSKTNELKSEK 873
PRK10476 PRK10476
multidrug transporter subunit MdtN;
588-708 1.78e-03

multidrug transporter subunit MdtN;


Pssm-ID: 182488 [Multi-domain]  Cd Length: 346  Bit Score: 42.71  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  588 SLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRER---DAACQQLEALEKeKAAKLEILQQQLQAANEAQDSAQ 664
Cdd:PRK10476    87 TVAQAQADLALADAQIMTTQRSVDAERSNAASANEQVERARanaKLATRTLERLEP-LLAKGYVSAQQVDQARTAQRDAE 165

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1196773644  665 NSVTQAQREKAELSQKVEELHALIEAAHQEqcEAQTQVAALEAR 708
Cdd:PRK10476   166 VSLNQALLQAQAAAAAVGGVDALVAQRAAR--EAALAIAELHLE 207
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 580-686 1.90e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 42.79  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  580 HQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSlrerDAACQQLEALEKE----KAAKLEILQQQLQA 655
Cdd:TIGR04320  247 TPIPNPPNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAY----AAAQAALATAQKElanaQAQALQTAQNNLAT 322

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1196773644  656 ANEAQDSAQNSVTQAQREKAELSQKVEELHA 686
Cdd:TIGR04320  323 AQAALANAEARLAKAKEALANLNADLAKKQA 353
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 586-888 1.90e-03

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 43.30  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  586 SGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEA-LEKEKAAKLEiLQQQLQAANEAQDSAQ 664
Cdd:pfam09726  358 SSSSKNSKKQKGPGGKSGARHKDPAENCIPNNQLSKPDALVRLEQDIKKLKAeLQASRQTEQE-LRSQISSLTSLERSLK 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  665 NSVTQAQREKAELSQKveeLHALIEAAHQEQceaQTqVAALEARLKAEQQKATEREKvaqekaQLQEqlwslEESLKitk 744
Cdd:pfam09726  437 SELGQLRQENDLLQTK---LHNAVSAKQKDK---QT-VQQLEKRLKAEQEARASAEK------QLAE-----EKKRK--- 495

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  745 gSLEEEKCRAAAALEEhqhhisemeAESRSLAEQHKQERKELEEEKAKrrgLGVQLqQLAETHQAETKALRQELAKARTS 824
Cdd:pfam09726  496 -KEEEATAARAVALAA---------ASRGECTESLKQRKRELESEIKK---LTHDI-KLKEEQIRELEIKVQELRKYKES 561

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1196773644  825 nnmaEREVELLVKEVKTWRKR---YEDSQQGETQYGL---------QEQLTTLKEEYEKSCQELRETKEKMAGIEA 888
Cdd:pfam09726  562 ----EKDTEVLMSALSAMQDKnqhLENSLSAETRIKLdlfsalgdaKRQLEIAQGQIYQKDQEIKDLKQKIAEVMA 633
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 649-794 2.03e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 42.80  E-value: 2.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  649 LQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHAL---IEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQE 725
Cdd:pfam00529   56 YQAALDSAEAQLAKAQAQVARLQAELDRLQALESELAISrqdYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPI 135

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1196773644  726 KAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRR 794
Cdd:pfam00529  136 GGISRESLVTAGALVAQAQANLLATVAQLDQIYVQITQSAAENQAEVRSELSGAQLQIAEAEAELKLAK 204
PRK09039 PRK09039
peptidoglycan -binding protein;
1047-1129 2.23e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.65  E-value: 2.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1047 LALEKAAKAELEMR---LQNALNEQQAEFANLQEA---LSRALSEKEGKDQELSK-LCEQEAV---QRMELKELLQTVEQ 1116
Cdd:PRK09039    69 LSLERQGNQDLQDSvanLRASLSAAEAERSRLQALlaeLAGAGAAAEGRAGELAQeLDSEKQVsarALAQVELLNQQIAA 148

                           90       100
                   ....*....|....*....|...
gi 1196773644 1117 LKAQLA----------KKEKEQQ 1129
Cdd:PRK09039   149 LRRQLAaleaaldaseKRDRESQ 171
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 295-551 2.24e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 42.67  E-value: 2.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  295 EKQAASPLEPRELEELRG--KNESLTFRLHE--TLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFASNLQ------ 364
Cdd:NF033928    35 PKDGIPGLEPKDLLDLFQniRNHARSWSNLEpkIKQLANDLANYARNIVVTGNPIIDLINEMPIIKRGDLTEEElselpp 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  365 ------------QLQGALNEL---TEEHSKATQQWVEK----QAHLEKELSTALQDKKCLEEKN------EILQGKLSQL 419
Cdd:NF033928   115 iplssddkeivkELKEILEDLkndIKDYQQKADDVKKElddfENDLREELLPQLKLKKKLYDDNlgsdsiEELREKIDQL 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  420 EERLAQLPESPRQEKGEVLGDVLQL----------ESLKQEAAtlatnntqlQARVEMLENEQGQKEAQLlgershfeEE 489
Cdd:NF033928   195 EKEIEQLNKEYDDYVKLSFTGLAGGpiglaitggiFGSKAEKI---------RKEKNALIQEIDELQEQL--------KK 257

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1196773644  490 KQQLASLITNLQSSISNLSQAKEELEQASQaqgaKLNAQVASLTAELTTLSATLQQQDQELA 551
Cdd:NF033928   258 KNALLGSLERLQTSLDDILTRMEDALPALK----KLKGVWQSLLTDIDSSINALKEIDDADS 315
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 893-1176 2.26e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  893 QIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSKEVARLEalvrkageqqetaslellkeppktr 972
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE------------------------- 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  973 dresewveeqqgQQLCSTQAALRAMEREAEQMGTELEKLRAALMEsqgqqqeergqqereVARLTQERGQAEADLALEKA 1052
Cdd:COG4942     76 ------------QELAALEAELAELEKEIAELRAELEAQKEELAE---------------LLRALYRLGRQPPLALLLSP 128

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1053 AKAELEMRLQNALNEQQAEFANLQEALSRALsekegkdQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSA 1132
Cdd:COG4942    129 EDFLDAVRRLQYLKYLAPARREQAEELRADL-------AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLL 201

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1196773644 1133 RGASGENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADS 1176
Cdd:COG4942    202 ARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 971-1713 3.00e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 3.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  971 TRDRESEWVEEQQGQQLCSTQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGQQEREVARLTQERGQAEADLALE 1050
Cdd:pfam01576    1 TRQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHEL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1051 KAAKAELEMRLQNALNEQQAEFANLQEaLSRALSEKEGKDQ--ELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQ 1128
Cdd:pfam01576   81 ESRLEEEEERSQQLQNEKKKMQQHIQD-LEEQLDEEEAARQklQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1129 QQSargasgENASGMGTQSEAVGKMEALRAKVSKLEQQCQQQQEEADSLARSLESERafhverdRALETLQGQLEEKARE 1208
Cdd:pfam01576  160 RIS------EFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAK-------RKLEGESTDLQEQIAE 226

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1209 LgysqaasasaQRELATLRAKAQdhsKAEEEWKAQVARGQQEAVRKGSLISSLEEevsiLNRQVLEKEgESKELKRLVIA 1288
Cdd:pfam01576  227 L----------QAQIAELRAQLA---KKEEELQAALARLEEETAQKNNALKKIRE----LEAQISELQ-EDLESERAARN 288

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1289 ESEKSQK-LEERLRLLQME---TASNSARAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERA-EELGQELKAW 1363
Cdd:pfam01576  289 KAEKQRRdLGEELEALKTEledTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQAlEELTEQLEQA 368

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1364 QEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPL 1443
Cdd:pfam01576  369 KRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSL 448

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1444 rqkVAEQERAAQQLRAEKASYAEQLsmlKKAHGLLAEENRglgERANLGRQFLEVELDQAR-EKYIQELAAVRGDAETRL 1522
Cdd:pfam01576  449 ---LNEAEGKNIKLSKDVSSLESQL---QDTQELLQEETR---QKLNLSTRLRQLEDERNSlQEQLEEEEEAKRNVERQL 519

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1523 AEMRQEVQSTTHELEVMTAKYEGAKvkvlEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQE 1602
Cdd:pfam01576  520 STLQAQLSDMKKKLEEDAGTLEALE----EGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQL 595

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1603 AQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDAKKQQ----NQELQEQLQGLEQLQKENKELRAEAERLGQELQQ 1678
Cdd:pfam01576  596 VSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRalslARALEEALEAKEELERTNKQLRAEMEDLVSSKDD 675

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 1196773644 1679 AGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRE 1713
Cdd:pfam01576  676 VGKNVHELERSKRALEQQVEEMKTQLEELEDELQA 710
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 171-521 3.05e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.79  E-value: 3.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  171 NLTEDLEIFLQKVPVSPTCSSTFSEDLSPPSHQ-----AKREVHFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQM 245
Cdd:pfam05483  293 HLTKELEDIKMSLQRSMSTQKALEEDLQIATKTicqltEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRL 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  246 RRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRI-DRLALLNEKQAASPLEprelEELRGKNESLTFRLHET 324
Cdd:pfam05483  373 EKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILaEDEKLLDEKKQFEKIA----EELKGKEQELIFLLQAR 448

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  325 LKQCQDL-------KTEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATqqwVEKQAHLEKELST 397
Cdd:pfam05483  449 EKEIHDLeiqltaiKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMT---LELKKHQEDIINC 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  398 ALQDKKCLEEKnEILQGKLSQLEERLAQLPESPRQEKGEVlgdVLQLESLKQEAATLATNNTQLQARVEMLENEQGQKEA 477
Cdd:pfam05483  526 KKQEERMLKQI-ENLEEKEMNLRDELESVREEFIQKGDEV---KCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKK 601

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1196773644  478 QLLGERSHFEEEKQQLASL-----ITNLQSSISNLSQAKEELEQASQAQ 521
Cdd:pfam05483  602 QIENKNKNIEELHQENKALkkkgsAENKQLNAYEIKVNKLELELASAKQ 650
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
405-671 3.26e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 3.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  405 LEEKNEILQGKLSQLEERLAQLpespRQEKGEVlgdvlqleSLKQEAATLATNNTQLQARVEMLENEQGQKEAQLlgers 484
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEF----RQKNGLV--------DLSEEAKLLLQQLSELESQLAEARAELAEAEARL----- 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  485 hfeeekQQLASLITNLQSSISNLSQAkeELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQaqkkqaql 564
Cdd:COG3206    243 ------AALRAQLGSGPDALPELLQS--PVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ-------- 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  565 aqslqqqeqasqgLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQetslrerdaacQQLEALEKEKAA 644
Cdd:COG3206    307 -------------LQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELE-----------AELRRLEREVEV 362

                          250       260
                   ....*....|....*....|....*..
gi 1196773644  645 KLEILQQQLQAANEAQDSAQNSVTQAQ 671
Cdd:COG3206    363 ARELYESLLQRLEEARLAEALTVGNVR 389
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1209-1425 3.35e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1209 LGYSQAASASAQRELATLRAKAQDHSKAEEEWKAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVia 1288
Cdd:COG3883      4 LALAAPTPAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEI-- 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1289 eSEKSQKLEERLRLLQMETASNSA---------------------RAAERSSALREEVQSLREEVEKQRAASENLRQELA 1347
Cdd:COG3883     82 -EERREELGERARALYRSGGSVSYldvllgsesfsdfldrlsalsKIADADADLLEELKADKAELEAKKAELEAKLAELE 160

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1196773644 1348 SQAERAEELGQELKAWQEkffQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQVAAEKRHREELEQSKQAAGG 1425
Cdd:COG3883    161 ALKAELEAAKAELEAQQA---EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1081-1728 3.42e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.65  E-value: 3.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1081 RALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGKMEALRAKV 1160
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1161 SKLEQQCQQQQEEADSLARSLESERAFHVERDRALETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEEW 1240
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1241 KAQVARGQQEAVRKGSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKlEERLRLLQMETASNSARAAERSSA 1320
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSS-AAKLKEEELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1321 LREEVQSLREEVEKQRAASENLRQELA-SQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQ 1399
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEILEEEEESIeLKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1400 QLQAEQVAAEKRHREELE----QSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQ-----LSM 1470
Cdd:pfam02463  493 QKLEERSQKESKARSGLKvllaLIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQklvraLTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1471 LKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKV 1550
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1551 LEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQ 1630
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1631 MEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRH-LTAQVRSLEAQVAHADQ 1709
Cdd:pfam02463  733 KINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEkLKAQEEELRALEEELKE 812

                          650
                   ....*....|....*....
gi 1196773644 1710 QLRELGKFQVASDALKSRE 1728
Cdd:pfam02463  813 EAELLEEEQLLIEQEEKIK 831
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 1488-1629 3.46e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 42.03  E-value: 3.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1488 RANLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKV---LEERQRFQEERQKL 1564
Cdd:pfam00529   71 QAQVARLQAELDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLApigGISRESLVTAGALV 150

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1565 TAQVEELSKKLADYDQASKVQQQKLKAFQAqggESQQEAQRLQTQLNELQVQLSQKEQAAEHYKV 1629
Cdd:pfam00529  151 AQAQANLLATVAQLDQIYVQITQSAAENQA---EVRSELSGAQLQIAEAEAELKLAKLDLERTEI 212
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 622-831 3.52e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  622 ETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQE------- 694
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREElgerara 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  695 QCEAQTQVAALEARLKAEQ-----QKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEME 769
Cdd:COG3883     95 LYRSGGSVSYLDVLLGSESfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1196773644  770 AESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAERE 831
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
PRK11281 PRK11281
mechanosensitive channel MscK;
611-851 3.53e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  611 AQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLE--ILQQQLQAAneaqdsaQNSVTQAQREKAELsqkvEELHALI 688
Cdd:PRK11281    21 CLSSAFARAASNGDLPTEADVQAQLDALNKQKLLEAEdkLVQQDLEQT-------LALLDKIDRQKEET----EQLKQQL 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  689 EAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEE---------SLKITKGSLEEekcRAAAALE 759
Cdd:PRK11281    90 AQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLDQLQNaqndlaeynSQLVSLQTQPE---RAQAALY 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  760 EHQHHISE----------------------MEAESRSLAEQHKQERKELEEEkakrrglgVQLQQLAEthqaetkaLRQE 817
Cdd:PRK11281   167 ANSQRLQQirnllkggkvggkalrpsqrvlLQAEQALLNAQNDLQRKSLEGN--------TQLQDLLQ--------KQRD 230

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1196773644  818 LAKARTsnNMAEREVELLVKEVKtwRKRYEDSQQ 851
Cdd:PRK11281   231 YLTARI--QRLEHQLQLLQEAIN--SKRLTLSEK 260
COG4995 COG4995
Uncharacterized conserved protein, contains CHAT domain [Function unknown];
532-980 3.60e-03

Uncharacterized conserved protein, contains CHAT domain [Function unknown];


Pssm-ID: 444019 [Multi-domain]  Cd Length: 711  Bit Score: 42.26  E-value: 3.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  532 LTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQEQASQGLRHQVEQLSGSLKQKEKQLEEAARELDASRRDHA 611
Cdd:COG4995      2 LALALLALLAALLAALALALLALALLLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALA 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  612 QQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAA 691
Cdd:COG4995     82 LAALALALLAAALALALAAAALAALALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAAAAAA 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  692 HQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAE 771
Cdd:COG4995    162 AAALLALALALAAAALALLALLLAALAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALL 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  772 SRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSNNMAEREVELLVKEVKTWRKRYEDSQQ 851
Cdd:COG4995    242 ALAAAAAALAAAAAALLALAAALLLLAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALALLLLA 321

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  852 GETQYGLQEQLTTLKEEYEKSCQELRETKEKMAGIEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLST 931
Cdd:COG4995    322 ALLLLLAALALLALLLLLAAAALLAAALAAALALAAALALALLAALLLLLAALLALLLEALLLLLLALLAALLLLAAALL 401

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 1196773644  932 LQEKMAATSKEVARLEALVRKAGEQQETASLELLKEPPKTRDRESEWVE 980
Cdd:COG4995    402 ALAAAQLLRLLLAALALLLALAAYAAARLALLALIEYIILPDRLYAFVQ 450
PRK12705 PRK12705
hypothetical protein; Provisional
 649-793 3.63e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 42.39  E-value: 3.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  649 LQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELhaLIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQ 728
Cdd:PRK12705    25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKEL--LLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDN 102

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644  729 LQEQLWSLEESLKITKGSLEEEKCRAAAALEEhqhhISEMEAESrSLAEQHKQERKELEEEKAKR 793
Cdd:PRK12705   103 LENQLEEREKALSARELELEELEKQLDNELYR----VAGLTPEQ-ARKLLLKLLDAELEEEKAQR 162
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1322-1423 3.68e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 42.63  E-value: 3.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1322 REEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHtstqalvsellpakhlcQQL 1401
Cdd:PRK11448   141 ENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQL-----------------EQL 203

                           90       100
                   ....*....|....*....|...
gi 1196773644 1402 QAEQVAAEKRHREEL-EQSKQAA 1423
Cdd:PRK11448   204 QEKAAETSQERKQKRkEITDQAA 226
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1270-1675 3.86e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 42.42  E-value: 3.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1270 RQVLEKEGESKELKRLVIAESEKSQKLEERLRLLQmetasnsARAAERSSALREEVQSLREEVEKQRAASENLRQELASQ 1349
Cdd:pfam05557   27 RARIELEKKASALKRQLDRESDRNQELQKRIRLLE-------KREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1350 AERAE---ELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL----LPAKHLCQQLQAEQ---VAAEKRHRE-ELEQ 1418
Cdd:pfam05557  100 ADAREvisCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLkakaSEAEQLRQNLEKQQsslAEAEQRIKElEFEI 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1419 SKQAAGGLRTELMRAQRElgelvplrqKVAEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEENRGLgeRANLGRQ---- 1494
Cdd:pfam05557  180 QSQEQDSEIVKNSKSELA---------RIPELEKELERLREHN----KHLNENIENKLLLKEEVEDL--KRKLEREekyr 244

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1495 ----FLEVELD------QAREKYIQELA-------AVRGDAETRLAE---MRQEVQSTTHELEVMTAKYEGAKVKVLEER 1554
Cdd:pfam05557  245 eeaaTLELEKEkleqelQSWVKLAQDTGlnlrspeDLSRRIEQLQQReivLKEENSSLTSSARQLEKARRELEQELAQYL 324

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1555 QRFQEERQKL---TAQVEELSKKLADYDQASKVQQQKLKAF---QAQGGESQQEAQRL----------QTQLNELQVQLS 1618
Cdd:pfam05557  325 KKIEDLNKKLkrhKALVRRLQRRVLLLTKERDGYRAILESYdkeLTMSNYSPQLLERIeeaedmtqkmQAHNEEMEAQLS 404

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1196773644 1619 QKEQAAEHYKVQMEKAKTHYDAKKQQNQEL--QEQLQGLEQLQKENKELRAEAERLGQE 1675
Cdd:pfam05557  405 VAEEELGGYKQQAQTLERELQALRQQESLAdpSYSKEEVDSLRRKLETLELERQRLREQ 463
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
578-749 4.00e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 4.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  578 LRHQVEQLSGSLKQKEKQLEEAARE-----LDASRRDHAQQLATAAKAQETSLRERDAACQQLEALEKEKAAKLEILQQQ 652
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEFRQKnglvdLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  653 LQaaNEAQDSAQNSVTQAQREKAELSQKVEELH----------------------ALIEAAHQEQCEAQTQVAALEARLK 710
Cdd:COG3206    260 LQ--SPVIQQLRAQLAELEAELAELSARYTPNHpdvialraqiaalraqlqqeaqRILASLEAELEALQAREASLQAQLA 337

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1196773644  711 AEQQKATEREKVAQEKAQLQEQLWSLEESLKITKGSLEE 749
Cdd:COG3206    338 QLEARLAELPELEAELRRLEREVEVARELYESLLQRLEE 376
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 293-962 4.03e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.40  E-value: 4.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  293 LNEKQAASPLEPRELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEENGDLSFKLREFA------------ 360
Cdd:pfam05483  108 LQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEyereetrqvymd 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  361 --SNLQQLQGALNELT--------EEHSKATQQWvEKQAHLEKELSTALQDK---------KCLEEKN---------EIL 412
Cdd:pfam05483  188 lnNNIEKMILAFEELRvqaenarlEMHFKLKEDH-EKIQHLEEEYKKEINDKekqvsllliQITEKENkmkdltfllEES 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  413 QGKLSQLEERLAQLPESPRQ--EKGEVLGDVLQ--LESLKQEAATLATNNTQLQARVEMLENEQGQKEAQLlgerSHFEE 488
Cdd:pfam05483  267 RDKANQLEEKTKLQDENLKEliEKKDHLTKELEdiKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQM----EELNK 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  489 EKQQLASLITNLQSSISNLsqakEELEQASQAQGAKLNAQVASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSL 568
Cdd:pfam05483  343 AKAAHSFVVTEFEATTCSL----EELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDE 418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  569 QQQEQasqglRHQVEQLSGSLKQKEKQLEEAARELDASRRDHAQQLATAAKAQETSLRERDAACQQLEAlEKEKAAKLEI 648
Cdd:pfam05483  419 KLLDE-----KKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEK-EKLKNIELTA 492

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  649 LQQQLQAANE--AQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKatEREKVAQEK 726
Cdd:pfam05483  493 HCDKLLLENKelTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKG--DEVKCKLDK 570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  727 AQLQEQLWSLEESLKITKGSLEEEKC-RAAAALEEHQHHISEMEAESRSLAEQHKQERKELEEEKAKRRGLGVQLQQLAE 805
Cdd:pfam05483  571 SEENARSIEYEVLKKEKQMKILENKCnNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQ 650

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  806 THQAETKALRQELAKARTSNnmaerevELLVKEVktwrkryedsqqgETQYGLQEQLTTLKEEYEKSCQelretkEKMAG 885
Cdd:pfam05483  651 KFEEIIDNYQKEIEDKKISE-------EKLLEEV-------------EKAKAIADEAVKLQKEIDKRCQ------HKIAE 704

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1196773644  886 IEAHSELQIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLSTLQEKMAATSK--EVARLEALVRKAGEQQETASL 962
Cdd:pfam05483  705 MVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKqlEIEKEEKEKLKMEAKENTAIL 783
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1429-1737 4.18e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 4.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1429 ELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGER-ANLGRQFLEVELD-QAREK 1506
Cdd:PRK03918   201 ELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKiRELEERIEELKKEiEELEE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1507 YIQELAAVRGDAET--RLAEMRQEVQSTTHELEVMTAKYEgAKVKVLEERQrfqEERQKLTAQVEELSKKLADYDQASKV 1584
Cdd:PRK03918   281 KVKELKELKEKAEEyiKLSEFYEEYLDELREIEKRLSRLE-EEINGIEERI---KELEEKEERLEELKKKLKELEKRLEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1585 QQQKLKAFQaqggesqqEAQRLQTQLNELQVQLSQKEqaAEHYKVQMEKAKThydAKKQQNQELQEQLQGLEQLQKENKE 1664
Cdd:PRK03918   357 LEERHELYE--------EAKAKKEELERLKKRLTGLT--PEKLEKELEELEK---AKEEIEEEISKITARIGELKKEIKE 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1665 LRAEAERL----------GQELQQaglktKEAEQTCRHLTAQVRSLEAQVAHADQQLRELGKFQVASDALKSREPQAKPQ 1734
Cdd:PRK03918   424 LKKAIEELkkakgkcpvcGRELTE-----EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498


                   ...
gi 1196773644 1735 LDL 1737
Cdd:PRK03918   499 KEL 501
46 PHA02562
endonuclease subunit; Provisional
 645-887 4.92e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 4.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  645 KLEILQQQLQAANEAQDSAQNSVTQAQrekAELSQKVEELHALIEAAHQEQCEAQTQVAALEarlkAEQQKATER-EKVA 723
Cdd:PHA02562   189 KIDHIQQQIKTYNKNIEEQRKKNGENI---ARKQNKYDELVEEAKTIKAEIEELTDELLNLV----MDIEDPSAAlNKLN 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  724 QEKAQLQEQLWSLEESLKItkgsleeekcraaaaLEEHQH------HISEMEAESRSLAEQHKQERKELEEEKAKRRGLG 797
Cdd:PHA02562   262 TAAAKIKSKIEQFQKVIKM---------------YEKGGVcptctqQISEGPDRITKIKDKLKELQHSLEKLDTAIDELE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  798 VQLQQLAEThQAETKALRQELAKARTSnnmaereVELLVKEVKTWRKRYEDsqqgetqygLQEQLTTLKEEYEKSCQELR 877
Cdd:PHA02562   327 EIMDEFNEQ-SKKLLELKNKISTNKQS-------LITLVDKAKKVKAAIEE---------LQAEFVDNAEELAKLQDELD 389

                          250
                   ....*....|
gi 1196773644  878 ETKEKMAGIE 887
Cdd:PHA02562   390 KIVKTKSELV 399
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 225-478 5.01e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 5.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  225 FLSGSPASPMGDILQTPQFQMRRLKKQLADERNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLAllnekqaasplep 304
Cdd:COG4942      9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE------------- 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  305 RELEELRGKNESLTFRLHETLKQCQDLKTEKGQMDRKINQLSEE-------NGDLSFKLREFASNLQQLQGALNELTEEH 377
Cdd:COG4942     76 QELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQpplalllSPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  378 SKATQQWVEKQAHLEKELSTALQDKKCLEEKNEILQGKLSQLEERLAQLPEsprqekgevlgdvlQLESLKQEAATLATN 457
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEK--------------ELAELAAELAELQQE 221

                          250       260
                   ....*....|....*....|.
gi 1196773644  458 NTQLQARVEMLENEQGQKEAQ 478
Cdd:COG4942    222 AEELEALIARLEAEAAAAAER 242
PRK09039 PRK09039
peptidoglycan -binding protein;
578-684 5.02e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 41.49  E-value: 5.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  578 LRHQVEQLSGSLKQKE---KQLEEAARELDASRRDHAQQLA--TAAKAQETSLRERDAA-----CQQLEALEKEKAAkle 647
Cdd:PRK09039    79 LQDSVANLRASLSAAEaerSRLQALLAELAGAGAAAEGRAGelAQELDSEKQVSARALAqvellNQQIAALRRQLAA--- 155

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1196773644  648 iLQQQLQAAnEAQDSAQNSVTQA--QREKAELSQKVEEL 684
Cdd:PRK09039   156 -LEAALDAS-EKRDRESQAKIADlgRRLNVALAQRVQEL 192
mukB PRK04863
chromosome partition protein MukB;
1395-1715 5.08e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 5.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1395 KHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGE----LVPLRQKVAEQERAAQQLRAEKASYAEQLSm 1470
Cdd:PRK04863   260 KHLITESTNYVAADYMRHANERRVHLEEALELRRELYTSRRQLAAeqyrLVEMARELAELNEAESDLEQDYQAASDHLN- 338

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1471 lkkahgllaeenrglgeRANLGRQFLEVEldqarEKYIQELaavrGDAETRLAEMRQEVqstthelevmtakyEGAKVKV 1550
Cdd:PRK04863   339 -----------------LVQTALRQQEKI-----ERYQADL----EELEERLEEQNEVV--------------EEADEQQ 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1551 LEERQRFQEERQkltaQVEELSKKLADYDQASKVQQQK-------------------------------LKAFQAQGGES 1599
Cdd:PRK04863   379 EENEARAEAAEE----EVDELKSQLADYQQALDVQQTRaiqyqqavqalerakqlcglpdltadnaedwLEEFQAKEQEA 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1600 QQEAQRLQTQLNELQVQLSQKEQAAEHYK-----VQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKELR------AE 1668
Cdd:PRK04863   455 TEELLSLEQKLSVAQAAHSQFEQAYQLVRkiageVSRSEAWDVARELLRRLREQRHLAEQLQQLRMRLSELEqrlrqqQR 534

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1196773644 1669 AERLGQELQQAGLKTKEAEQTCRHLTAQvrsLEAQVAHADQQLRELG 1715
Cdd:PRK04863   535 AERLLAEFCKRLGKNLDDEDELEQLQEE---LEARLESLSESVSEAR 578
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 801-1152 5.09e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 42.13  E-value: 5.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  801 QQLAETHQAETKALRQELAKARTSNNMAEREVellvkevkTWR-KRYEDSQQGETQYglQEQLTTLKEEYEKSCQELRET 879
Cdd:NF012221  1452 QDLSNLTAGEVIALSFDFARRAGLSTNNGIEV--------LWNgEVVFASSGDASAW--QQKTLKLTAKAGSNRLEFKGT 1521

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  880 KEK------MAGIEAHSEL-QIGQHQSELAQLHANLARALQQVQEKENRAQKLADDLstlQEKMAATSKEVARLEALVRK 952
Cdd:NF012221  1522 GHNdglgyiLDNVVATSESsQQADAVSKHAKQDDAAQNALADKERAEADRQRLEQEK---QQQLAAISGSQSQLESTDQN 1598

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  953 A----GEQQETASLE-------LLKEPPKTRD--RESEWVEEQQGQQLcSTQAALRAMEREAEQM-------GTELEKLR 1012
Cdd:NF012221  1599 AletnGQAQRDAILEesravtkELTTLAQGLDalDSQATYAGESGDQW-RNPFAGGLLDRVQEQLddakkisGKQLADAK 1677

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1013 AALMESQGQQQEERGQQEREVARLTQERGQAEADLAlekAAKAELEMRLQNALNEQQ-AEFANLQEALSRALSEKEGkDQ 1091
Cdd:NF012221  1678 QRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDID---DAKADAEKRKDDALAKQNeAQQAESDANAAANDAQSRG-EQ 1753

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1196773644 1092 ElSKLCEQEAVQrmelkellqtvEQLKAQLAKKEKEQQQSARGASGENASGMGTQSEAVGK 1152
Cdd:NF012221  1754 D-ASAAENKANQ-----------AQADAKGAKQDESDKPNRQGAAGSGLSGKAYSVEGVAE 1802
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1592-1714 5.23e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.19  E-value: 5.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1592 FQAQGGESQQEAQRLQTQLNELQVQLSQKEQAA------EHYKVQMEKAKTHYDAKKQQNQELQEQLQGLEQLQKENKEL 1665
Cdd:COG1566     81 LQAALAQAEAQLAAAEAQLARLEAELGAEAEIAaaeaqlAAAQAQLDLAQRELERYQALYKKGAVSQQELDEARAALDAA 160

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1196773644 1666 RAEAERLGQELQQAGLKTKEAEQTcRHLTAQVRSLEAQVAHADQQLREL 1714
Cdd:COG1566    161 QAQLEAAQAQLAQAQAGLREEEEL-AAAQAQVAQAEAALAQAELNLART 208
mukB PRK04863
chromosome partition protein MukB;
746-1506 5.53e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.87  E-value: 5.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  746 SLEEEKCRAAAALEEHQHHISEMeaesrslaeqhkqeRKELEEEKAKRRGLGVQLQQLAETHQAETKALRQELAKARTSN 825
Cdd:PRK04863   290 ELRRELYTSRRQLAAEQYRLVEM--------------ARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQA 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  826 NMAEREVELlvkevktwrkrYEDSQQGETQYGLQEQLTTLKEEYEKSCQELR----------ETKEKMAGI--EAHSELQ 893
Cdd:PRK04863   356 DLEELEERL-----------EEQNEVVEEADEQQEENEARAEAAEEEVDELKsqladyqqalDVQQTRAIQyqQAVQALE 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  894 IGQHQSELAQLHANLARALQQvqEKENRAQKLADDLSTLQEKMAATSKEVARLE---ALVRK-AGEQQETASLELLKEpp 969
Cdd:PRK04863   425 RAKQLCGLPDLTADNAEDWLE--EFQAKEQEATEELLSLEQKLSVAQAAHSQFEqayQLVRKiAGEVSRSEAWDVARE-- 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  970 KTRDRESEWVEEQQGQQLcstQAALRAMEREAEQMGTELEKLRAALMESQGQQQEERGqqereVARLTQERGQAEADLAL 1049
Cdd:PRK04863   501 LLRRLREQRHLAEQLQQL---RMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDE-----LEQLQEELEARLESLSE 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1050 EKAAKAELEMRLQNALNEQQAEFANL----------QEALSRaLSEKEGKDQELSKLCEQeAVQRMELKELLQTVEQLKA 1119
Cdd:PRK04863   573 SVSEARERRMALRQQLEQLQARIQRLaarapawlaaQDALAR-LREQSGEEFEDSQDVTE-YMQQLLERERELTVERDEL 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1120 QLAKKE-KEQQQSARGASGENASGMGTQSEAVGKM-----------------EALRAK------VSKLEQQCQQQQEE-- 1173
Cdd:PRK04863   651 AARKQAlDEEIERLSQPGGSEDPRLNALAERFGGVllseiyddvsledapyfSALYGParhaivVPDLSDAAEQLAGLed 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1174 ---------------ADSLARSLESERAFHVE---------------------RDRALETLQGQLEEKArelgysqaasa 1217
Cdd:PRK04863   731 cpedlyliegdpdsfDDSVFSVEELEKAVVVKiadrqwrysrfpevplfgraaREKRIEQLRAEREELA----------- 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1218 saqRELATLRAKAQDHSKAEEEWKAQVarGQQEAVrkgSLISSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLE 1297
Cdd:PRK04863   800 ---ERYATLSFDVQKLQRLHQAFSRFI--GSHLAV---AFEADPEAELRQLNRRRVELERALADHESQEQQQRSQLEQAK 871

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1298 ERLRLLQmetasnsaRAAERSSALREEvqSLREEVEkqraasenlrqELASQAERAEELGQELKAWQEKFFQKEQALSAL 1377
Cdd:PRK04863   872 EGLSALN--------RLLPRLNLLADE--TLADRVE-----------EIREQLDEAEEAKRFVQQHGNALAQLEPIVSVL 930

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1378 QLEHTSTQALVSELLPAKHLCQQLQAEQVA-AEKRHR----------EELEQSKQAAGGLRTELMRAQRELGEL-VPLRQ 1445
Cdd:PRK04863   931 QSDPEQFEQLKQDYQQAQQTQRDAKQQAFAlTEVVQRrahfsyedaaEMLAKNSDLNEKLRQRLEQAEQERTRArEQLRQ 1010

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196773644 1446 KVAEQERAAQQLRAEKASYAEQLSMLKKAHGLLAE----ENRGLGERANLGRQFLEVELDQAREK 1506
Cdd:PRK04863  1011 AQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDlgvpADSGAEERARARRDELHARLSANRSR 1075
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1313-1637 5.98e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 5.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1313 RAAERSSALREEVQSLREEVEKQRAASENLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELL 1392
Cdd:COG4372     42 KLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQ 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1393 PAKHLCQQLQAEQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQE--RAAQQLRAEKASYAEQLSM 1470
Cdd:COG4372    122 KERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEaeQALDELLKEANRNAEKEEE 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1471 LKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYIQELAAVRGDAETRLAEMRQEVQSTTHELEVMTAKYEGAKVKV 1550
Cdd:COG4372    202 LAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIA 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1551 LEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQ 1630
Cdd:COG4372    282 ALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSK 361


                   ....*..
gi 1196773644 1631 MEKAKTH 1637
Cdd:COG4372    362 GAEAGVA 368
PRK11281 PRK11281
mechanosensitive channel MscK;
1395-1625 6.21e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 6.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1395 KHLCQQLQA--EQVAAEKRHREELEQSKQAAGGLRTELMRAQRELGELVPLRQKVAEQERAAQQLRAEKASYAEQLSMLK 1472
Cdd:PRK11281    59 KLVQQDLEQtlALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLDQLQ 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1473 KAHGLLAEENRGLgeranlgrqfleVELDQAREKYIQELAAvrgdAETRLAEMRQEVQSTThelevmtakyEGAKVKVLE 1552
Cdd:PRK11281   139 NAQNDLAEYNSQL------------VSLQTQPERAQAALYA----NSQRLQQIRNLLKGGK----------VGGKALRPS 192

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1196773644 1553 ERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKeQAAE 1625
Cdd:PRK11281   193 QRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSEK-TVQE 264
PRK12472 PRK12472
hypothetical protein; Provisional
 597-731 6.54e-03

hypothetical protein; Provisional


Pssm-ID: 237110 [Multi-domain]  Cd Length: 508  Bit Score: 41.39  E-value: 6.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  597 EEAARELD--ASRRDHAQQLATAAKAQETSLRerdAACQQLEALEKEKAAKLEILQQQLQAANEAQDSAQnsvtqAQREK 674
Cdd:PRK12472   193 ETLAREAEdaARAADEAKTAAAAAAREAAPLK---ASLRKLERAKARADAELKRADKALAAAKTDEAKAR-----AEERQ 264

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1196773644  675 AELSQKVEELHALIEAAHQEQCEAQTQVAALEARLKAEQQKATEREKVAQEKAQLQE 731
Cdd:PRK12472   265 QKAAQQAAEAATQLDTAKADAEAKRAAAAATKEAAKAAAAKKAETAKAATDAKLALE 321
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1520-1736 7.25e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 7.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1520 TRLAEMRQEVQSTTHELEVMTakyegakvKVLEERQRFQEERQKLTAQvEELSKKLADYdqaskVQQQKLKAFQAQGGES 1599
Cdd:COG4913    235 DDLERAHEALEDAREQIELLE--------PIRELAERYAAARERLAEL-EYLRAALRLW-----FAQRRLELLEAELEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1600 QQEAQRLQTQLNELQVQLSQKEQAAEHYKVQMEKAKThydakkqqnqelqeqlQGLEQLQKENKELRAEAERLGQELQQA 1679
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQIRGNGG----------------DRLEQLEREIERLERELEERERRRARL 364

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1196773644 1680 GLKTKEAEQTCRHLTAQVRSLEAQVAHADQQL-RELGKFQVASDALKSREPQAKPQLD 1736
Cdd:COG4913    365 EALLAALGLPLPASAEEFAALRAEAAALLEALeEELEALEEALAEAEAALRDLRRELR 422
mukB PRK04863
chromosome partition protein MukB;
256-516 7.42e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.48  E-value: 7.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  256 RNNRDELELELAEHRKLLTEKDAQISMMQQRIDRLAllnekqaasplepRELEELRGKNESLTFRLhETLKQCQDLKTEK 335
Cdd:PRK04863   781 RAAREKRIEQLRAEREELAERYATLSFDVQKLQRLH-------------QAFSRFIGSHLAVAFEA-DPEAELRQLNRRR 846

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  336 GQMDRKINQLSEENGDLSF---KLREFASNLQQLQGALNELTEEHskatqqWVEKQAHLEKELSTALQDKKCLEEKneil 412
Cdd:PRK04863   847 VELERALADHESQEQQQRSqleQAKEGLSALNRLLPRLNLLADET------LADRVEEIREQLDEAEEAKRFVQQH---- 916

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  413 QGKLSQLEERLAQLPESPRQE---KGEVLGDVLQLESLKQEAATL----------------------ATNNTQLQARVEM 467
Cdd:PRK04863   917 GNALAQLEPIVSVLQSDPEQFeqlKQDYQQAQQTQRDAKQQAFALtevvqrrahfsyedaaemlaknSDLNEKLRQRLEQ 996

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1196773644  468 LENEQGQKEAQLLGERSHFEEEKQQLASLITNLQSSISNLSQAKEELEQ 516
Cdd:PRK04863   997 AEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQD 1045
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 282-671 8.08e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.36  E-value: 8.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  282 MMQQRIDRLALLNEKQAASPLEpRELEELRGKNESLTFRLHETLKQCQDLK-TEKGQMDRKINQLSEENGDLSFKLREFA 360
Cdd:NF012221  1457 LTAGEVIALSFDFARRAGLSTN-NGIEVLWNGEVVFASSGDASAWQQKTLKlTAKAGSNRLEFKGTGHNDGLGYILDNVV 1535

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  361 --SNLQQLQGALNELTEEhSKATQQwvekqahlekelstALQDKKCLEEKNEIL-QGKLSQLEE---RLAQLpESPRQEK 434
Cdd:NF012221  1536 atSESSQQADAVSKHAKQ-DDAAQN--------------ALADKERAEADRQRLeQEKQQQLAAisgSQSQL-ESTDQNA 1599

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  435 GEVLGDVlQLESLKQEAATLATNNTQLQARVEMLeNEQGQKEAQLlGE--RSHF------------EEEKQQLASLITNL 500
Cdd:NF012221  1600 LETNGQA-QRDAILEESRAVTKELTTLAQGLDAL-DSQATYAGES-GDqwRNPFagglldrvqeqlDDAKKISGKQLADA 1676

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  501 QSSIS-NLSQAKEELEQ--ASQAQGAKLNAQV------ASLTAELTTLSATLQQQDQELAGLKQQAQKKQAQLAQSLQQQ 571
Cdd:NF012221  1677 KQRHVdNQQKVKDAVAKseAGVAQGEQNQANAeqdiddAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  572 EQASQGlrHQVEQLSGSLKQKEKqleeaarelDASRRDHAQqlATAAKAQETSLRERDAACQQLEALEKEKAAKL--EIL 649
Cdd:NF012221  1757 AAENKA--NQAQADAKGAKQDES---------DKPNRQGAA--GSGLSGKAYSVEGVAEPGSHINPDSPAAADGRfsEGL 1823

                          410       420
                   ....*....|....*....|..
gi 1196773644  650 QQQLQaanEAQDSAQNSVTQAQ 671
Cdd:NF012221  1824 TEQEQ---EALEGATNAVNRLQ 1842
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1512-1717 8.15e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.18  E-value: 8.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1512 AAVRGDAETRLA---EMRQEVQSTTHELEVMTAKYEGAKvkvlEERQRFQEERQKLTAQVEELSKKLADydqasKVQQQK 1588
Cdd:PRK02224   233 RETRDEADEVLEeheERREELETLEAEIEDLRETIAETE----REREELAEEVRDLRERLEELEEERDD-----LLAEAG 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1589 LKAFQAQGGESQQEAqrLQTQLNELQVQLSQKEQAAEHYKVQMEKAKTHYDakkqqnqelqeqlqgleQLQKENKELRAE 1668
Cdd:PRK02224   304 LDDADAEAVEARREE--LEDRDEELRDRLEECRVAAQAHNEEAESLREDAD-----------------DLEERAEELREE 364

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1196773644 1669 AERLGQELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRELGKF 1717
Cdd:PRK02224   365 AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDF 413
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
635-820 8.72e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 41.01  E-value: 8.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  635 LEALEKEKAAklEILQQQLQAANEAQDSAQNSVTQAQREK--AELSQKVEelhalIEAAHQEQCEAQTQVAALEARLKAE 712
Cdd:COG2268    186 LDALGRRKIA--EIIRDARIAEAEAERETEIAIAQANREAeeAELEQERE-----IETARIAEAEAELAKKKAEERREAE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  713 QQKATEREKVAQEKAQLQEQLwsleeslkitkgsleeekcraaaaleEHQHHISEMEAESRslAEQHKQERKELEEEKAK 792
Cdd:COG2268    259 TARAEAEAAYEIAEANAEREV--------------------------QRQLEIAEREREIE--LQEKEAEREEAELEADV 310

                          170       180
                   ....*....|....*....|....*...
gi 1196773644  793 RRGLGVQLQQLAETHQAETKALRQELAK 820
Cdd:COG2268    311 RKPAEAEKQAAEAEAEAEAEAIRAKGLA 338
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1080-1728 8.84e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.31  E-value: 8.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1080 SRALSEKEGKDQELSKLCEQEAVQRMELKELLQTVEQLKAQLAKKEKEQQqsargasgenasgmgTQSEAVGKMEALRAK 1159
Cdd:pfam01576    1 TRQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQ---------------AETELCAEAEEMRAR 65

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1160 VSKLEQQCQQQQEEADSLARSlESERAFHVERDRalETLQGQLEEKARELGYSQAASASAQRELATLRAKAQDHSKAEEE 1239
Cdd:pfam01576   66 LAARKQELEEILHELESRLEE-EEERSQQLQNEK--KKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILL 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1240 WKAQVARGQQEAvrkgsliSSLEEEVSILNRQVLEKEGESKELKRLVIAESEKSQKLEERLRllQMETASNSARAAERss 1319
Cdd:pfam01576  143 LEDQNSKLSKER-------KLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLK--KEEKGRQELEKAKR-- 211

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1320 ALREEVQSLREEVEKQRAASENLRQELASQAEraeelgqELKAWQEKFFQKEQALSALQLEHTSTQALVSELLpakhlcq 1399
Cdd:pfam01576  212 KLEGESTDLQEQIAELQAQIAELRAQLAKKEE-------ELQAALARLEEETAQKNNALKKIRELEAQISELQ------- 277

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1400 qlqaEQVAAEKRHREELEQSKQAAG----GLRTELMRAQRELGELVPLRQK-VAEQERAAQQLRAEKASYAEQLSMLKKA 1474
Cdd:pfam01576  278 ----EDLESERAARNKAEKQRRDLGeeleALKTELEDTLDTTAAQQELRSKrEQEVTELKKALEEETRSHEAQLQEMRQK 353

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1475 HGLLAEENRGLGERANLGRQFLEvELDQAREKYIQELAA-------VRGDAETRLAEMRQEVQstthELEVMTAKYEGAK 1547
Cdd:pfam01576  354 HTQALEELTEQLEQAKRNKANLE-KAKQALESENAELQAelrtlqqAKQDSEHKRKKLEGQLQ----ELQARLSESERQR 428

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1548 VKVLEERQRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQL-------NELQVQLSQK 1620
Cdd:pfam01576  429 AELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLrqlederNSLQEQLEEE 508

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644 1621 EQAAEHYKVQMEkakTHYDAKKQQNQELQEQLQGLEQLQKENKELRAEAERLGQELQQAGLKTKEAEQTCRHLTAQVRSL 1700
Cdd:pfam01576  509 EEAKRNVERQLS---TLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDL 585

                          650       660
                   ....*....|....*....|....*...
gi 1196773644 1701 EAQVAHADQQLRELGKFQVASDALKSRE 1728
Cdd:pfam01576  586 LVDLDHQRQLVSNLEKKQKKFDQMLAEE 613
PRK11637 PRK11637
AmiB activator; Provisional
 634-856 8.85e-03

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 40.83  E-value: 8.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  634 QLEALEKEKAAKLE-----ILQQQLQAANEAQDSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAA-LEA 707
Cdd:PRK11637    53 QQDIAAKEKSVRQQqqqraSLLAQLKKQEEAISQASRKLRETQNTLNQLNKQIDELNASIAKLEQQQAAQERLLAAqLDA 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  708 RLKAEQQKATEReKVAQEKAQLQEQLWSLEESLKITKGSLEEEKCRAAAALEEHQHHISEMEAESRSLAEQHKQERKELE 787
Cdd:PRK11637   133 AFRQGEHTGLQL-ILSGEESQRGERILAYFGYLNQARQETIAELKQTREELAAQKAELEEKQSQQKTLLYEQQAQQQKLE 211

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1196773644  788 EEKAKRR----GLGVQL----QQLAETHQAETKaLRQELAKA-RTSNNMAEREvellVKEVKTWRKRYEDSQQGETQY 856
Cdd:PRK11637   212 QARNERKktltGLESSLqkdqQQLSELRANESR-LRDSIARAeREAKARAERE----AREAARVRDKQKQAKRKGSTY 284
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1555-1630 9.15e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.09  E-value: 9.15e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1196773644 1555 QRFQEERQKLTAQVEELSKKLADYDQASKVQQQKLKAFQAQGGESQQEAQRLQTQLNELQVQLSQKEQAAEHYKVQ 1630
Cdd:PRK11448   145 HALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERKQKRKE 220
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 244-819 9.18e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.48  E-value: 9.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  244 QMRRLKKQLADERNNRDELELELAEHRklltekdaqismmQQRIDRLALLNEKQAASPLEPRELEELRGKNESLTFR--- 320
Cdd:COG3096    537 LLEEFCQRIGQQLDAAEELEELLAELE-------------AQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARapa 603

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  321 ---LHETLKQCQDLK----TEKGQMDRKINQLSEENGDLSFKLREFASNLQQLQGALNELTEEHSKATQQWVEKQAHLEK 393
Cdd:COG3096    604 wlaAQDALERLREQSgealADSQEVTAAMQQLLEREREATVERDELAARKQALESQIERLSQPGGAEDPRLLALAERLGG 683

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  394 ELSTALQDKKCLEE-----------KNEILQGKLSQLEERLAQLPESPRQ----EKGEVLGDVLQLESLKQEAATLATNN 458
Cdd:COG3096    684 VLLSEIYDDVTLEDapyfsalygpaRHAIVVPDLSAVKEQLAGLEDCPEDlyliEGDPDSFDDSVFDAEELEDAVVVKLS 763

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  459 tQLQARVEMLENE----QGQKEAQLLGERSHFEEEKQQLASLITNLQsSISNLSQAKEE---------LEQASQAQGAKL 525
Cdd:COG3096    764 -DRQWRYSRFPEVplfgRAAREKRLEELRAERDELAEQYAKASFDVQ-KLQRLHQAFSQfvgghlavaFAPDPEAELAAL 841

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  526 NAQVASLTAELTTLSATLQQQDQELAGLKQQAQK----KQAQLAQSLQQQEQASQGLRHQVEQLSGS---LKQKEKQLEE 598
Cdd:COG3096    842 RQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLlnklLPQANLLADETLADRLEELREELDAAQEAqafIQQHGKALAQ 921

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  599 AARELDASRRDhAQQLATAAKAQETSLRERDAACQQLEALEK------------------EKAAKLEILQQQLQAANEAQ 660
Cdd:COG3096    922 LEPLVAVLQSD-PEQFEQLQADYLQAKEQQRRLKQQIFALSEvvqrrphfsyedavgllgENSDLNEKLRARLEQAEEAR 1000

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  661 DSAQNSVTQAQREKAELSQKVEELHALIEAAHQEQCEAQTQVAALEARL--KAEQQKATEREKVAQEKAQLQEQLWSLEE 738
Cdd:COG3096   1001 REAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQAdaEAEERARIRRDELHEELSQNRSRRSQLEK 1080

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196773644  739 SLKITKGSLEeekcraaaaleehqhhisEMEAESRSLAEQHKQERKELEEEKAKrrglGVQLQQLAETHQAETKALRQEL 818
Cdd:COG3096   1081 QLTRCEAEMD------------------SLQKRLRKAERDYKQEREQVVQAKAG----WCAVLRLARDNDVERRLHRREL 1138


                   .
gi 1196773644  819 A 819
Cdd:COG3096   1139 A 1139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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