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Conserved domains on  [gi|1720426824|ref|XP_030099238|]
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indoleamine 2,3-dioxygenase 2 isoform X3 [Mus musculus]

Protein Classification

PrnB family protein( domain architecture ID 230504)

PrnB family protein is a DUF1864 domain-containing protein; similar to Pseudomonas fluorescens monodechloroaminopyrrolnitrin synthase PrnB and Haliotis myoglobin

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
IDO super family cl21721
Indoleamine 2,3-dioxygenase;
15-240 4.34e-104

Indoleamine 2,3-dioxygenase;


The actual alignment was detected with superfamily member pfam01231:

Pssm-ID: 473941  Cd Length: 406  Bit Score: 309.47  E-value: 4.34e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720426824  15 SLGRYHISEEYGFL-LPNPLEALPDHYKPWMEIALRLPHLIENRQLRAHVYRMPLLDCRFLKSYREQRLAHMALAAITMG 93
Cdd:pfam01231   1 ALEDYDVSPETGFLpPELPLERLPDYYEPWEAIADNLPALILSGRLRAVVDKLPVLSTDQLESELELRRAHLVLAFLTHA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720426824  94 FVWQEGEgQPQKVLPRSLAIPFVEVSRNLGLPPILVHSDLVLTNWTKRN-PEGPLEISNLETIISFPGGESLRGFILVTV 172
Cdd:pfam01231  81 YVWGEGD-KPSEVLPPSIAVPLLEVSEHLGLPPVLTYADLVLWNWKPIDgPEDPMDLDNLRILNTFTGTEDESWFYLVSV 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720426824 173 LVEKAAVPGLKALVQGMEAIRQHSQDTLLEALQQLRLSIQDITRALAQMHDYVDPDIFYSVIRIFLSG 240
Cdd:pfam01231 160 AIEARGAPALPLMLQAIDAARDGDAARVTSALQSLAEVIDELGLLLMRMYEHCDPHVFYHRIRPFLAG 227
 
Name Accession Description Interval E-value
IDO pfam01231
Indoleamine 2,3-dioxygenase;
15-240 4.34e-104

Indoleamine 2,3-dioxygenase;


Pssm-ID: 460123  Cd Length: 406  Bit Score: 309.47  E-value: 4.34e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720426824  15 SLGRYHISEEYGFL-LPNPLEALPDHYKPWMEIALRLPHLIENRQLRAHVYRMPLLDCRFLKSYREQRLAHMALAAITMG 93
Cdd:pfam01231   1 ALEDYDVSPETGFLpPELPLERLPDYYEPWEAIADNLPALILSGRLRAVVDKLPVLSTDQLESELELRRAHLVLAFLTHA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720426824  94 FVWQEGEgQPQKVLPRSLAIPFVEVSRNLGLPPILVHSDLVLTNWTKRN-PEGPLEISNLETIISFPGGESLRGFILVTV 172
Cdd:pfam01231  81 YVWGEGD-KPSEVLPPSIAVPLLEVSEHLGLPPVLTYADLVLWNWKPIDgPEDPMDLDNLRILNTFTGTEDESWFYLVSV 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720426824 173 LVEKAAVPGLKALVQGMEAIRQHSQDTLLEALQQLRLSIQDITRALAQMHDYVDPDIFYSVIRIFLSG 240
Cdd:pfam01231 160 AIEARGAPALPLMLQAIDAARDGDAARVTSALQSLAEVIDELGLLLMRMYEHCDPHVFYHRIRPFLAG 227
PRK10433 PRK10433
putative RNA methyltransferase; Provisional
198-265 5.78e-03

putative RNA methyltransferase; Provisional


Pssm-ID: 236693  Cd Length: 228  Bit Score: 37.27  E-value: 5.78e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720426824 198 DTLLEALQQLRLSIQDITRALAQMHDYVDPDIFYSVIRIFLSGFNQVAIQFTNQQSRFTFERLCLVDL 265
Cdd:PRK10433   62 DTLAEALHDVDFTVATTARSRAKFHYYATPAELVPLLEEKSSWMSHAALVFGREDSGLTNEELALADV 129
 
Name Accession Description Interval E-value
IDO pfam01231
Indoleamine 2,3-dioxygenase;
15-240 4.34e-104

Indoleamine 2,3-dioxygenase;


Pssm-ID: 460123  Cd Length: 406  Bit Score: 309.47  E-value: 4.34e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720426824  15 SLGRYHISEEYGFL-LPNPLEALPDHYKPWMEIALRLPHLIENRQLRAHVYRMPLLDCRFLKSYREQRLAHMALAAITMG 93
Cdd:pfam01231   1 ALEDYDVSPETGFLpPELPLERLPDYYEPWEAIADNLPALILSGRLRAVVDKLPVLSTDQLESELELRRAHLVLAFLTHA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720426824  94 FVWQEGEgQPQKVLPRSLAIPFVEVSRNLGLPPILVHSDLVLTNWTKRN-PEGPLEISNLETIISFPGGESLRGFILVTV 172
Cdd:pfam01231  81 YVWGEGD-KPSEVLPPSIAVPLLEVSEHLGLPPVLTYADLVLWNWKPIDgPEDPMDLDNLRILNTFTGTEDESWFYLVSV 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720426824 173 LVEKAAVPGLKALVQGMEAIRQHSQDTLLEALQQLRLSIQDITRALAQMHDYVDPDIFYSVIRIFLSG 240
Cdd:pfam01231 160 AIEARGAPALPLMLQAIDAARDGDAARVTSALQSLAEVIDELGLLLMRMYEHCDPHVFYHRIRPFLAG 227
PRK10433 PRK10433
putative RNA methyltransferase; Provisional
198-265 5.78e-03

putative RNA methyltransferase; Provisional


Pssm-ID: 236693  Cd Length: 228  Bit Score: 37.27  E-value: 5.78e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720426824 198 DTLLEALQQLRLSIQDITRALAQMHDYVDPDIFYSVIRIFLSGFNQVAIQFTNQQSRFTFERLCLVDL 265
Cdd:PRK10433   62 DTLAEALHDVDFTVATTARSRAKFHYYATPAELVPLLEEKSSWMSHAALVFGREDSGLTNEELALADV 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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