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Conserved domains on  [gi|1720387087|ref|XP_030104981|]
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protein NLRC3 isoform X8 [Mus musculus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1006001)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNA1 super family cl34950
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 5-247 8.56e-53

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


The actual alignment was detected with superfamily member COG5238:

Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 180.76  E-value: 8.56e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087   5 LAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTI 84
Cdd:COG5238   187 LGCNQIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTV 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  85 SMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCS 164
Cdd:COG5238   267 ETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQE 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 165 NQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENhSLTHLHLQWNFIQAGAARALGQ 244
Cdd:COG5238   347 NTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTN-RLHTLILDGNLIGAEAQQRLEQ 425


                  ...
gi 1720387087 245 ALQ 247
Cdd:COG5238   426 LLE 428
RNA1 super family cl34950
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 158-363 1.16e-22

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


The actual alignment was detected with superfamily member COG5238:

Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 98.32  E-value: 1.16e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 158 LMRALCsNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDrgAQAIAVAVGENHSLTHLHLQWNFIQAG 237
Cdd:COG5238   119 LRRIMA-KTLEDSLILYLALPRRINLIQVLKDPLGGNAVHLLGLAARLGLL--AAISMAKALQNNSVETVYLGCNQIGDE 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 238 AARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLRGNDVGAAGAKALANALKLNSSLRRLNLQENS 317
Cdd:COG5238   196 GIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQ 275

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1720387087 318 LGMDGAIFVASALSENHGLHHINLQGNPIGESAARMISEAIKTNAP 363
Cdd:COG5238   276 IGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKT 321
 
Name Accession Description Interval E-value
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 5-247 8.56e-53

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 180.76  E-value: 8.56e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087   5 LAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTI 84
Cdd:COG5238   187 LGCNQIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTV 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  85 SMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCS 164
Cdd:COG5238   267 ETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQE 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 165 NQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENhSLTHLHLQWNFIQAGAARALGQ 244
Cdd:COG5238   347 NTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTN-RLHTLILDGNLIGAEAQQRLEQ 425


                  ...
gi 1720387087 245 ALQ 247
Cdd:COG5238   426 LLE 428
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 5-290 2.19e-33

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 126.32  E-value: 2.19e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087   5 LAENQIGNKGAKALARSLLVNRSLITLDLRSNSIG--PPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVaEALVSNQ 82
Cdd:cd00116    30 LEGNTLGEEAAKALASALRPQPSLKELCLSLNETGriPRGLQSLLQGLTKGCGLQELDLSDNALGPDGCGVL-ESLLRSS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  83 TISMLQLQKNLIGLIGAQQMADALKQNR-SLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRA 161
Cdd:cd00116   109 SLQELKLNNNGLGDRGLRLLAKGLKDLPpALEKLVLGRNRLEGASCEALAKALRANRDLKELNLANNGIGDAGIRALAEG 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 162 LCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVgenhslthlhlqwnfiqagaara 241
Cdd:cd00116   189 LKANCNLEVLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNLTDAGAAALASAL----------------------- 245

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1720387087 242 lgqaLQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLRGNDV 290
Cdd:cd00116   246 ----LSPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKF 290
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 158-363 1.16e-22

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 98.32  E-value: 1.16e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 158 LMRALCsNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDrgAQAIAVAVGENHSLTHLHLQWNFIQAG 237
Cdd:COG5238   119 LRRIMA-KTLEDSLILYLALPRRINLIQVLKDPLGGNAVHLLGLAARLGLL--AAISMAKALQNNSVETVYLGCNQIGDE 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 238 AARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLRGNDVGAAGAKALANALKLNSSLRRLNLQENS 317
Cdd:COG5238   196 GIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQ 275

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1720387087 318 LGMDGAIFVASALSENHGLHHINLQGNPIGESAARMISEAIKTNAP 363
Cdd:COG5238   276 IGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKT 321
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 244-363 3.07e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 42.34  E-value: 3.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 244 QALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLRGNDVGAAGAKALANALKL--NSSLRRLNLQENSLGMD 321
Cdd:cd00116    17 ELLPKLLCLQVLRLEGNTLGEEAAKALASALRPQPSLKELCLSLNETGRIPRGLQSLLQGLtkGCGLQELDLSDNALGPD 96

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1720387087 322 GAIFVASALSeNHGLHHINLQGNPIGESAARMISEAIKTNAP 363
Cdd:cd00116    97 GCGVLESLLR-SSSLQELKLNNNGLGDRGLRLLAKGLKDLPP 137
LRR_6 pfam13516
Leucine Rich repeat;
249-271 1.16e-03

Leucine Rich repeat;


Pssm-ID: 463907 [Multi-domain]  Cd Length: 24  Bit Score: 35.67  E-value: 1.16e-03
                          10        20
                  ....*....|....*....|...
gi 1720387087 249 NRTLTTLDLQENAIGDEGASSVA 271
Cdd:pfam13516   2 NTHLTTLDLSDNDIGDEGAEALA 24
LRR_RI smart00368
Leucine rich repeat, ribonuclease inhibitor type;
25-51 2.26e-03

Leucine rich repeat, ribonuclease inhibitor type;


Pssm-ID: 197686 [Multi-domain]  Cd Length: 28  Bit Score: 35.08  E-value: 2.26e-03
                           10        20
                   ....*....|....*....|....*..
gi 1720387087   25 NRSLITLDLRSNSIGPPGAKALADALK 51
Cdd:smart00368   1 NPSLRELDLSNNKLGDEGARALAEALK 27
 
Name Accession Description Interval E-value
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 5-247 8.56e-53

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 180.76  E-value: 8.56e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087   5 LAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTI 84
Cdd:COG5238   187 LGCNQIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTV 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  85 SMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCS 164
Cdd:COG5238   267 ETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQE 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 165 NQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENhSLTHLHLQWNFIQAGAARALGQ 244
Cdd:COG5238   347 NTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTN-RLHTLILDGNLIGAEAQQRLEQ 425


                  ...
gi 1720387087 245 ALQ 247
Cdd:COG5238   426 LLE 428
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 23-265 1.35e-47

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 166.89  E-value: 1.35e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  23 LVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQM 102
Cdd:COG5238   177 LQNNSVETVYLGCNQIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIAL 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 103 ADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEG 182
Cdd:COG5238   257 AEALKNNTTVETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQG 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 183 AQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRtLTTLDLQENAI 262
Cdd:COG5238   337 AIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTNR-LHTLILDGNLI 415


                  ...
gi 1720387087 263 GDE 265
Cdd:COG5238   416 GAE 418
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 59-359 4.83e-47

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 165.35  E-value: 4.83e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  59 LSLQSNVIKDDGVMCVAEALvSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQ 138
Cdd:COG5238   158 LLGLAARLGLLAAISMAKAL-QNNSVETVYLGCNQIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNK 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 139 ILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAV 218
Cdd:COG5238   237 SLTTLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGL 316

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 219 GENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTlialylrgndvgaagakal 298
Cdd:COG5238   317 QGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLEGNTT------------------- 377

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720387087 299 analklnssLRRLNLQENSLGMDGAIFVASALSENHgLHHINLQGNPIGESAARMISEAIK 359
Cdd:COG5238   378 ---------LRELNLGKNNIGKQGAEALIDALQTNR-LHTLILDGNLIGAEAQQRLEQLLE 428
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 80-361 7.86e-45

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 159.57  E-value: 7.86e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  80 SNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSsNTIGDRGAIALAEALKvNQILENLDLQSNSISDMGVTVLM 159
Cdd:COG5238   124 AKTLEDSLILYLALPRRINLIQVLKDPLGGNAVHLLGLA-ARLGLLAAISMAKALQ-NNSVETVYLGCNQIGDEGIEELA 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 160 RALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAA 239
Cdd:COG5238   202 EALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGA 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 240 RALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLRGNDVGAAGAKALANALKLNSSLRRLNLQENSLG 319
Cdd:COG5238   282 IALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIG 361

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1720387087 320 MDGAIFVASALSENHGLHHINLQGNPIGESAARMISEAIKTN 361
Cdd:COG5238   362 DEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTN 403
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 4-192 3.87e-34

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 130.68  E-value: 3.87e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087   4 SLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQT 83
Cdd:COG5238   242 DLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKT 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  84 ISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALC 163
Cdd:COG5238   322 LHTLNLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQ 401

                         170       180
                  ....*....|....*....|....*....
gi 1720387087 164 SNQtLSSLNLRENSISPEGAQALTQALCR 192
Cdd:COG5238   402 TNR-LHTLILDGNLIGAEAQQRLEQLLER 429
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 5-290 2.19e-33

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 126.32  E-value: 2.19e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087   5 LAENQIGNKGAKALARSLLVNRSLITLDLRSNSIG--PPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVaEALVSNQ 82
Cdd:cd00116    30 LEGNTLGEEAAKALASALRPQPSLKELCLSLNETGriPRGLQSLLQGLTKGCGLQELDLSDNALGPDGCGVL-ESLLRSS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  83 TISMLQLQKNLIGLIGAQQMADALKQNR-SLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRA 161
Cdd:cd00116   109 SLQELKLNNNGLGDRGLRLLAKGLKDLPpALEKLVLGRNRLEGASCEALAKALRANRDLKELNLANNGIGDAGIRALAEG 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 162 LCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVgenhslthlhlqwnfiqagaara 241
Cdd:cd00116   189 LKANCNLEVLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNLTDAGAAALASAL----------------------- 245

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1720387087 242 lgqaLQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLRGNDV 290
Cdd:cd00116   246 ----LSPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKF 290
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 86-357 6.70e-31

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 119.38  E-value: 6.70e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  86 MLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIG--DRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALc 163
Cdd:cd00116    27 VLRLEGNTLGEEAAKALASALRPQPSLKELCLSLNETGriPRGLQSLLQGLTKGCGLQELDLSDNALGPDGCGVLESLL- 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 164 SNQTLSSLNLRENSISPEGAQALTQALCRNN-TLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARAL 242
Cdd:cd00116   106 RSSSLQELKLNNNGLGDRGLRLLAKGLKDLPpALEKLVLGRNRLEGASCEALAKALRANRDLKELNLANNGIGDAGIRAL 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 243 GQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLRGNDVGAA-GAKALANALKLNSSLRRLNLQENSLGMD 321
Cdd:cd00116   186 AEGLKANCNLEVLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNLTDAgAAALASALLSPNISLLTLSLSCNDITDD 265

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1720387087 322 GAIFVASALSENHGLHHINLQGNPIGESAARMISEA 357
Cdd:cd00116   266 GAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAES 301
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 87-359 1.60e-30

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 118.61  E-value: 1.60e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  87 LQLQKNLIGLIGAQQMADALKQnrsLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSI--SDMGVTVLMRALCS 164
Cdd:cd00116     3 LSLKGELLKTERATELLPKLLC---LQVLRLEGNTLGEEAAKALASALRPQPSLKELCLSLNETgrIPRGLQSLLQGLTK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 165 NQTLSSLNLRENSISPEGAQALtQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGEN-HSLTHLHLQWNFIQAGAARALG 243
Cdd:cd00116    80 GCGLQELDLSDNALGPDGCGVL-ESLLRSSSLQELKLNNNGLGDRGLRLLAKGLKDLpPALEKLVLGRNRLEGASCEALA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 244 QALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLRGNDVGAAGAKALANALKLNSSLRRLNLQENSLGMDGA 323
Cdd:cd00116   159 KALRANRDLKELNLANNGIGDAGIRALAEGLKANCNLEVLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNLTDAGA 238

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1720387087 324 IFVASAL-SENHGLHHINLQGNPIGESAARMISEAIK 359
Cdd:cd00116   239 AALASALlSPNISLLTLSLSCNDITDDGAKDLAEVLA 275
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 3-250 3.66e-30

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 117.46  E-value: 3.66e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087   3 GSLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKiNRTLTSLSLQSNVIKDDGVMCVAEALVSNQ 82
Cdd:cd00116    58 LSLNETGRIPRGLQSLLQGLTKGCGLQELDLSDNALGPDGCGVLESLLR-SSSLQELKLNNNGLGDRGLRLLAKGLKDLP 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  83 -TISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRA 161
Cdd:cd00116   137 pALEKLVLGRNRLEGASCEALAKALRANRDLKELNLANNGIGDAGIRALAEGLKANCNLEVLDLNNNGLTDEGASALAET 216

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 162 LCSNQTLSSLNLRENSISPEGAQAL-TQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAAR 240
Cdd:cd00116   217 LASLKSLEVLNLGDNNLTDAGAAALaSALLSPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQ 296

                         250
                  ....*....|
gi 1720387087 241 ALGQALQLNR 250
Cdd:cd00116   297 LLAESLLEPG 306
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 158-363 1.16e-22

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 98.32  E-value: 1.16e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 158 LMRALCsNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDrgAQAIAVAVGENHSLTHLHLQWNFIQAG 237
Cdd:COG5238   119 LRRIMA-KTLEDSLILYLALPRRINLIQVLKDPLGGNAVHLLGLAARLGLL--AAISMAKALQNNSVETVYLGCNQIGDE 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 238 AARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLRGNDVGAAGAKALANALKLNSSLRRLNLQENS 317
Cdd:COG5238   196 GIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQ 275

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1720387087 318 LGMDGAIFVASALSENHGLHHINLQGNPIGESAARMISEAIKTNAP 363
Cdd:COG5238   276 IGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKT 321
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
7-349 1.36e-06

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 49.93  E-value: 1.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087   7 ENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNvikddgvmcvaEALVSNQTISM 86
Cdd:COG4886    49 LTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-----------EELSNLTNLES 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  87 LQLQKNLIgligaQQMADALKQNRSLKALMFSSNTIGDrgaiaLAEALKVNQILENLDLQSNSISDMGvtvlmRALCSNQ 166
Cdd:COG4886   118 LDLSGNQL-----TDLPEELANLTNLKELDLSNNQLTD-----LPEPLGNLTNLKSLDLSNNQLTDLP-----EELGNLT 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 167 TLSSLNLRENSISpegaqALTQALCRNNTLKHLDLTANLLHDrgaqaIAVAVGENHSLTHLHLQWNFIqagaaRALGQAL 246
Cdd:COG4886   183 NLKELDLSNNQIT-----DLPEPLGNLTNLEELDLSGNQLTD-----LPEPLANLTNLETLDLSNNQL-----TDLPELG 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 247 QLNRtLTTLDLQENAIGDegassvAGALKVNTTLIALYLRGNDVGAAGAKALANALKLNSSLRRLNLQENSLGMDGAIFV 326
Cdd:COG4886   248 NLTN-LEELDLSNNQLTD------LPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLL 320

                         330       340
                  ....*....|....*....|...
gi 1720387087 327 ASALSENHGLHHINLQGNPIGES 349
Cdd:COG4886   321 TTLLLLLLLLKGLLVTLTTLALS 343
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
10-315 2.47e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 42.61  E-value: 2.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  10 IGNKGAKALARSLLVNRSLITLDLRSNSIgppgaKALADALKINRTLTSLSLQSNVIKDdgvmcVAEALVSNQTISMLQL 89
Cdd:COG4886   120 LSGNQLTDLPEELANLTNLKELDLSNNQL-----TDLPEPLGNLTNLKSLDLSNNQLTD-----LPEELGNLTNLKELDL 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  90 QKNLIgligaQQMADALKQNRSLKALMFSSNTIGDrgaiaLAEALKVNQILENLDLQSNSISDMgvtvlmRALCSNQTLS 169
Cdd:COG4886   190 SNNQI-----TDLPEPLGNLTNLEELDLSGNQLTD-----LPEPLANLTNLETLDLSNNQLTDL------PELGNLTNLE 253

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 170 SLNLRENSIS--PEGAQaltqalcrNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQ 247
Cdd:COG4886   254 ELDLSNNQLTdlPPLAN--------LTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLL 325

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720387087 248 LNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLRGNDVGAAGAKALANALKLNSSLRRLNLQE 315
Cdd:COG4886   326 LLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLL 393
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 244-363 3.07e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 42.34  E-value: 3.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 244 QALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLRGNDVGAAGAKALANALKL--NSSLRRLNLQENSLGMD 321
Cdd:cd00116    17 ELLPKLLCLQVLRLEGNTLGEEAAKALASALRPQPSLKELCLSLNETGRIPRGLQSLLQGLtkGCGLQELDLSDNALGPD 96

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1720387087 322 GAIFVASALSeNHGLHHINLQGNPIGESAARMISEAIKTNAP 363
Cdd:cd00116    97 GCGVLESLLR-SSSLQELKLNNNGLGDRGLRLLAKGLKDLPP 137
LRR_6 pfam13516
Leucine Rich repeat;
249-271 1.16e-03

Leucine Rich repeat;


Pssm-ID: 463907 [Multi-domain]  Cd Length: 24  Bit Score: 35.67  E-value: 1.16e-03
                          10        20
                  ....*....|....*....|...
gi 1720387087 249 NRTLTTLDLQENAIGDEGASSVA 271
Cdd:pfam13516   2 NTHLTTLDLSDNDIGDEGAEALA 24
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
27-342 1.34e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 40.30  E-value: 1.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  27 SLITLDLRSNSIgppgaKALADALKINRTLTSLSLQSNVIKDdgvmcVAEALVSNQTISMLQLQKNLIgligaQQMADAL 106
Cdd:COG4886   114 NLESLDLSGNQL-----TDLPEELANLTNLKELDLSNNQLTD-----LPEPLGNLTNLKSLDLSNNQL-----TDLPEEL 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 107 KQNRSLKALMFSSNTIGDrgaiaLAEALKVNQILENLDLQSNSISDmgvtvLMRALCSNQTLSSLNLRENSIS--PEgaq 184
Cdd:COG4886   179 GNLTNLKELDLSNNQITD-----LPEPLGNLTNLEELDLSGNQLTD-----LPEPLANLTNLETLDLSNNQLTdlPE--- 245

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087 185 altqaLCRNNTLKHLDLTANLLHDRGAQaiavavGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGD 264
Cdd:COG4886   246 -----LGNLTNLEELDLSNNQLTDLPPL------ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELL 314

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720387087 265 EGASSVAGALKVNTTLIALYLRGNDVGAAGAKALANALKLNSSLRRLNLQENSLGMDGAIFVASALSENHGLHHINLQ 342
Cdd:COG4886   315 ILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLL 392
LRR_RI smart00368
Leucine rich repeat, ribonuclease inhibitor type;
25-51 2.26e-03

Leucine rich repeat, ribonuclease inhibitor type;


Pssm-ID: 197686 [Multi-domain]  Cd Length: 28  Bit Score: 35.08  E-value: 2.26e-03
                           10        20
                   ....*....|....*....|....*..
gi 1720387087   25 NRSLITLDLRSNSIGPPGAKALADALK 51
Cdd:smart00368   1 NPSLRELDLSNNKLGDEGARALAEALK 27
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 26-204 3.73e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 38.23  E-value: 3.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  26 RSLITLDLRSNSIgppgakALADALKINRTLTSLSLQSNVIKddgVMCVAEALV-------SNQTISM---LQLQKNLIG 95
Cdd:cd21340    24 KNLKVLYLYDNKI------TKIENLEFLTNLTHLYLQNNQIE---KIENLENLVnlkklylGGNRISVvegLENLTNLEE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720387087  96 L-IGAQQMADALKqnrslkaLMFSSNTIgdrgaIALAEALKVnqilenLDLQSNSISDMGVTVLMRALcsnqtlSSLNLR 174
Cdd:cd21340    95 LhIENQRLPPGEK-------LTFDPRSL-----AALSNSLRV------LNISGNNIDSLEPLAPLRNL------EQLDAS 150

                         170       180       190
                  ....*....|....*....|....*....|
gi 1720387087 175 ENSISpeGAQALTQALCRNNTLKHLDLTAN 204
Cdd:cd21340   151 NNQIS--DLEELLDLLSSWPSLRELDLTGN 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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