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Conserved domains on  [gi|1907176315|ref|XP_036008435|]
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nuclear mitotic apparatus protein 1 isoform X2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.15e-49

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


:

Pssm-ID: 411795  Cd Length: 148  Bit Score: 173.53  E-value: 1.15e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315    6 TRAATLLSWVNSLHVADPVETVLQLQDCSIFIKIINTIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315   86 KVIEG--SEMELAKMIMLFLYQSTMSSRNlrDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNL--TLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 554-1323 1.09e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 122.86  E-value: 1.09e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  554 LKLKEQQlEEAAKEQEATRQDHAQQLAIVAEAREA--SL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 630
Cdd:TIGR02168  168 SKYKERR-KETERKLERTRENLDRLEDILNELERQlkSLeRQAEKAERYKELKAELRELELALLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  631 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLkaeQQKTTEREKVVQEKAQLQEQLRALEESLKITKG 710
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL---YALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  711 SLEEEKRRaadaLKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHqaetEALRHELAEATASQ 790
Cdd:TIGR02168  324 QLEELESK----LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----ETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  791 HRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 870
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  871 AIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASlELLKEPPRAANRASDQLGEQQGRPFSST 950
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAAIEAALGGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  951 -HAAVKAMEREAEQMGG-----ELERLRAALIKSQGQQQEERGQQEREVA-RLTQERGQAQADL---------------A 1008
Cdd:TIGR02168  555 lNAAKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAkDLVKFDPKLRKALsyllggvlvvddldnA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1009 QEKAAKAELEMRLQnTLNEQRVE---FAALQEALAHALTekEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKE 1085
Cdd:TIGR02168  635 LELAKKLRPGYRIV-TLDGDLVRpggVITGGSAKTNSSI--LERRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1086 KEHPAGGASGEDASgpGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQG 1165
Cdd:TIGR02168  712 EELEQLRKELEELS--RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1166 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1245
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1246 ELKRLVVAESEKSQKLEERLRLL--QVETASNSARAAE-RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELG 1322
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY 949


                   .
gi 1907176315 1323 Q 1323
Cdd:TIGR02168  950 S 950
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1852-1910 4.55e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


:

Pssm-ID: 412093  Cd Length: 56  Bit Score: 102.68  E-value: 4.55e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315 1852 LLSLPGYRPTTRSSARRSQarmSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1910
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1117-1638 2.60e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.49  E-value: 2.60e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVA-ESEKSQKLEERLRLLQ--VETA 1273
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEaEEELEELAEELLEALRaaAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1274 SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1353
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1354 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL--------------MRAQRELGELGSLRQKIVEQERAA 1419
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavavligveaaYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1420 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQE 1493
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1494 AQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQT 1573
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315 1574 QLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQnqklQEQLQDLEELQKENKELRSEAERLG 1638
Cdd:COG1196    720 ELEEEALEEQLEAEREELLEELLEEEELLEEEALEE----LPEPPDLEELERELERLEREIEALG 780
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 213-814 1.97e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.24  E-value: 1.97e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  213 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALlnekqaassqepsELEELRGKNESLTVRLHE 292
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  293 TLKQCQNLKTEKSQMDRKISQLSEENgdlsfkvrefanhlqqlqgafndlieehskasQEWAEKQARLENELSTALQDKK 372
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEEL--------------------------------AELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  373 CLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLEcergKQEAQLLAER 452
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  453 SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQT 532
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  533 MQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLE 612
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  613 SLQ-QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashqeqrqVQARVTELEAQLKAEQQKTTEREKVVQEK 691
Cdd:COG1196    584 ARAaLAAALARGAIGAAVDLVASDLREADARYYVLGDTLL-----------GRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  692 AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 771
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907176315  772 HQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEAR 814
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
PRK06975 super family cl35524
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
 1552-1740 2.07e-03

bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed


The actual alignment was detected with superfamily member PRK06975:

Pssm-ID: 235899 [Multi-domain]  Cd Length: 656  Bit Score: 43.17  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1552 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQaaehyKLQMEKAKThydakkqqnQKLQEQLQDLeeLQKENKELR 1631
Cdd:PRK06975   357 QRQQANDAQTAELRVKTEQAQASVHQLDSQFAQLDG-----KLADAQSAQ---------QALEQQYQDL--SRNRDDWMI 420

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1632 SEAERLgreLQQAGLKTkeaeqtcrHLTAQVRSLEAQVAHADQQLRDLGKFQVAT---------DALKSrepqvKPQLDL 1702
Cdd:PRK06975   421 AEVEQM---LSSASQQL--------QLTGNVQLALIALQNADARLATSDSPQAVAvrkaiaqdiERLKA-----APSADL 484

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1703 S------------IDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASP 1740
Cdd:PRK06975   485 TglaiklddaiakIDALPLSGEALPPHATMAAAPAAAAAAAAAAAAAGEP 534
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.15e-49

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 173.53  E-value: 1.15e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315    6 TRAATLLSWVNSLHVADPVETVLQLQDCSIFIKIINTIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315   86 KVIEG--SEMELAKMIMLFLYQSTMSSRNlrDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNL--TLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 554-1323 1.09e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 122.86  E-value: 1.09e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  554 LKLKEQQlEEAAKEQEATRQDHAQQLAIVAEAREA--SL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 630
Cdd:TIGR02168  168 SKYKERR-KETERKLERTRENLDRLEDILNELERQlkSLeRQAEKAERYKELKAELRELELALLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  631 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLkaeQQKTTEREKVVQEKAQLQEQLRALEESLKITKG 710
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL---YALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  711 SLEEEKRRaadaLKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHqaetEALRHELAEATASQ 790
Cdd:TIGR02168  324 QLEELESK----LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----ETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  791 HRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 870
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  871 AIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASlELLKEPPRAANRASDQLGEQQGRPFSST 950
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAAIEAALGGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  951 -HAAVKAMEREAEQMGG-----ELERLRAALIKSQGQQQEERGQQEREVA-RLTQERGQAQADL---------------A 1008
Cdd:TIGR02168  555 lNAAKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAkDLVKFDPKLRKALsyllggvlvvddldnA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1009 QEKAAKAELEMRLQnTLNEQRVE---FAALQEALAHALTekEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKE 1085
Cdd:TIGR02168  635 LELAKKLRPGYRIV-TLDGDLVRpggVITGGSAKTNSSI--LERRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1086 KEHPAGGASGEDASgpGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQG 1165
Cdd:TIGR02168  712 EELEQLRKELEELS--RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1166 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1245
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1246 ELKRLVVAESEKSQKLEERLRLL--QVETASNSARAAE-RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELG 1322
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY 949


                   .
gi 1907176315 1323 Q 1323
Cdd:TIGR02168  950 S 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 515-1129 8.39e-27

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 119.66  E-value: 8.39e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  515 LASLKEQAKK-EQAQMLQTmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEqeatrqdhaqqlaivAEAREASLRER 593
Cdd:COG1196    202 LEPLERQAEKaERYRELKE-ELKELEAELLLLKLRELEAELEELEAELEELEAE---------------LEELEAELAEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  594 DTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQ 673
Cdd:COG1196    266 EAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  674 LKAEQQkttEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQqcratemeAESRSLMEQREREQKELEQ 753
Cdd:COG1196    346 LEEAEE---ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA--------AELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  754 EKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEarygamfQEQLMALK 833
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL-------AELLEELA 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  834 GEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDD-LSALQEKMAATNKEVACLKTLVLK 912
Cdd:COG1196    488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAaLAAALQNIVVEDDEVAAAAIEYLK 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  913 AGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQERE 992
Cdd:COG1196    568 AAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  993 VARLTQERGQAQADLAQEKAAKaelemrlqntlNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQ 1072
Cdd:COG1196    648 EVTLEGEGGSAGGSLTGGSRRE-----------LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176315 1073 TLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLE 1129
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1852-1910 4.55e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 102.68  E-value: 4.55e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315 1852 LLSLPGYRPTTRSSARRSQarmSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1910
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1117-1638 2.60e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.49  E-value: 2.60e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVA-ESEKSQKLEERLRLLQ--VETA 1273
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEaEEELEELAEELLEALRaaAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1274 SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1353
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1354 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL--------------MRAQRELGELGSLRQKIVEQERAA 1419
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavavligveaaYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1420 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQE 1493
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1494 AQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQT 1573
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315 1574 QLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQnqklQEQLQDLEELQKENKELRSEAERLG 1638
Cdd:COG1196    720 ELEEEALEEQLEAEREELLEELLEEEELLEEEALEE----LPEPPDLEELERELERLEREIEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 265-937 1.23e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 100.22  E-value: 1.23e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  265 KQAASSQEPSELEELRGKNESLTV----RLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAfn 340
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAeavkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-- 1280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  341 dliEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKlSQLEDQATRLQEspAPEKGEVLGDALQLDTLKQEA 420
Cdd:PTZ00121  1281 ---DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK-KKAEEAKKKADA--AKKKAEEAKKAAEAAKAEAEA 1354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  421 AKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTS 500
Cdd:PTZ00121  1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  501 MTGLNATLQQRDQELASLKEQAKKeqAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLA 580
Cdd:PTZ00121  1435 EAKKKAEEAKKADEAKKKAEEAKK--AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA 1512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  581 ivAEAREAS-LRERDTARQQLETVEKEKDAKLESLQQ--QLQAANDARDNAQtsVTQAQQEKAELSQKIGELHACIEASH 657
Cdd:PTZ00121  1513 --DEAKKAEeAKKADEAKKAEEAKKADEAKKAEEKKKadELKKAEELKKAEE--KKKAEEAKKAEEDKNMALRKAEEAKK 1588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  658 QEQRQVQA--RVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKgslEEEKRRAADALKEQQCRATEMEA 735
Cdd:PTZ00121  1589 AEEARIEEvmKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE---AEEKKKAEELKKAEEENKIKAAE 1665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  736 ESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQ 815
Cdd:PTZ00121  1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  816 QEEARYGAMFQEQLMALKG--EKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKA---IQQVQEKEVRAQKLVDDls 890
Cdd:PTZ00121  1746 AEEAKKDEEEKKKIAHLKKeeEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnFANIIEGGKEGNLVIND-- 1823

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 1907176315  891 aLQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASD 937
Cdd:PTZ00121  1824 -SKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEAD 1869
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 213-814 1.97e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.24  E-value: 1.97e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  213 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALlnekqaassqepsELEELRGKNESLTVRLHE 292
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  293 TLKQCQNLKTEKSQMDRKISQLSEENgdlsfkvrefanhlqqlqgafndlieehskasQEWAEKQARLENELSTALQDKK 372
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEEL--------------------------------AELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  373 CLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLEcergKQEAQLLAER 452
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  453 SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQT 532
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  533 MQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLE 612
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  613 SLQ-QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashqeqrqVQARVTELEAQLKAEQQKTTEREKVVQEK 691
Cdd:COG1196    584 ARAaLAAALARGAIGAAVDLVASDLREADARYYVLGDTLL-----------GRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  692 AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 771
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907176315  772 HQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEAR 814
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1003-1681 3.15e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 3.15e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1003 AQADLAQEKAAKAELEMRLqNTLNEQR---VEFAALQEALAHA-----LTEKEGTDQELAKLRGQEAAQRTELKELQQTL 1074
Cdd:TIGR02168  184 TRENLDRLEDILNELERQL-KSLERQAekaERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1075 EQLKIQLVKKEKEHPAGGASGEDASGpgtqsetagktdapgpELQALRAEISKLEQQCQQQQQQVEGLTHSLKseracra 1154
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQK----------------ELYALANEISRLEQQKQILRERLANLERQLE------- 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1155 EQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILN 1234
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1235 rqvlekegeskelKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQ 1314
Cdd:TIGR02168  400 -------------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1315 AERAEELGQELKAWQEKFFQKEQ---ALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKrFREELEQSKQAAGG- 1390
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALGg 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1391 -LQAELMR------------AQRELG-------------ELGSLRQKIVEQERAAQQLRAEKASYAEQLSM--------- 1435
Cdd:TIGR02168  546 rLQAVVVEnlnaakkaiaflKQNELGrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggv 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1436 -----LKKAHGLLAEENRGL-------------------GERANLGRQFLEVELDQAREKY-------------VQELAA 1478
Cdd:TIGR02168  626 lvvddLDNALELAKKLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIeeleekiaelekaLAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1479 VRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKV---LEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLK 1555
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVeqlEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1556 AFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAE 1635
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176315 1636 RLGRELQ---QAGLKTKEAEQTCRH--------LTAQVRSLEAQVAHADQQLRDLGK 1681
Cdd:TIGR02168  866 ELIEELEselEALLNERASLEEALAllrseleeLSEELRELESKRSELRRELEELRE 922
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 211-844 3.62e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 3.62e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  211 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPS--------ELEELRGK 282
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELEsrleeleeQLETLRSK 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  283 NESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANH------------LQQLQGAFNDLIEEHSKAS 350
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelqaeleeleeeLEELQEELERLEEALEELR 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  351 QEWAEKQARL---ENELSTALQDKKCLEEKNEILQG----------KLSQLEDQATRLQESPAPEKG------EVLGDAL 411
Cdd:TIGR02168  468 EELEEAEQALdaaERELAQLQARLDSLERLQENLEGfsegvkallkNQSGLSGILGVLSELISVDEGyeaaieAALGGRL 547

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  412 Q-------------LDTLKQEAAKLATD---NTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSN 475
Cdd:TIGR02168  548 QavvvenlnaakkaIAFLKQNELGRVTFlplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  476 LSQAKEELEQASQAQGAQLTAQLT--------SMTG----LNATLQQRDQELASLKEQakkeQAQMLQTMQEQEQAAQGL 543
Cdd:TIGR02168  628 VDDLDNALELAKKLRPGYRIVTLDgdlvrpggVITGgsakTNSSILERRREIEELEEK----IEELEEKIAELEKALAEL 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  544 RQQVEQLSSSLKLKEQQLEEAAKEQEATRQDhAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND 623
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  624 ARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQ-----------QKTTEREKVVQEKA 692
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATErrledleeqieELSEDIESLAAEIE 862

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  693 QLQEQLRALE---ESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE 769
Cdd:TIGR02168  863 ELEELIEELEselEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  770 EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRF--------EARQQEEARYGAMFQEQLMALKGEKTGQEV 841
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022


                   ...
gi 1907176315  842 QEE 844
Cdd:TIGR02168 1023 IEE 1025
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
243-750 3.78e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 75.08  E-value: 3.78e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  243 TEKDAQIAMMQQRIDHlALLNEKQAASSQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS 312
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  313 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQ 382
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  383 GKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQL 462
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  463 ASLIADLQSSVSNLSQAKEELEQA--------------------SQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQA 522
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAGkcpecgqpvegsphvetieeDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  523 K-----KEQAQMLQ--------TMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaiVAEAREAS 589
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEARE--------EVAELNSK 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  590 LRERDTARQQLETVEkEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACI-EASHQEQRQVQARVT 668
Cdd:PRK02224   581 LAELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFdEARIEEAREDKERAE 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  669 ELEAQLKAE-QQKTTEREKVVQEKAQLQEQLRALEEsLKITKGSLeEEKRRAADALKEQQCRATEMEAESRSLMEQRERE 747
Cdd:PRK02224   660 EYLEQVEEKlDELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLRAELRQRNVE 737


                   ...
gi 1907176315  748 QKE 750
Cdd:PRK02224   738 TLE 740
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 512-1339 4.40e-12

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 71.93  E-value: 4.40e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  512 DQELASLKEQAKKEQAQmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQlAIVAEAREASLR 591
Cdd:pfam02463  159 EEEAAGSRLKRKKKEAL-KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE-YLLYLDYLKLNE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  592 ERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhacIEASHQEQRQVQARVTELE 671
Cdd:pfam02463  237 ERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKE---EEELKSELLKLERRKVDDE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  672 AQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKEL 751
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  752 EQEKAGRKGLEARIQqlEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMA 831
Cdd:pfam02463  394 EEELELKSEEEKEAQ--LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  832 LKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEK-----------------EVRAQKLVDDLSALQE 894
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDgvggriisahgrlgdlgVAVENYKVAISTAVIV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  895 KMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPF--SSTHAAVKAMEREAEQMGGELERLR 972
Cdd:pfam02463  552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNlaQLDKATLEADEDDKRAKVVEGILKD 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  973 AALIKSQGQQQEERGQQEREVARL-----TQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKE 1047
Cdd:pfam02463  632 TELTKLKESAKAKESGLRKGVSLEeglaeKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1048 GTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpagGASGEDASGPGTQSETAGKTDAPGPELQALRAEISK 1127
Cdd:pfam02463  712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEE----EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1128 LEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKA 1207
Cdd:pfam02463  788 VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEE 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1208 QVARG------QQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAE 1281
Cdd:pfam02463  868 LLQELllkeeeLEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADE 947

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176315 1282 RSSA------LREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQAL 1339
Cdd:pfam02463  948 KEKEennkeeEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAI 1011
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 450-648 8.99e-12

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 71.02  E-value: 8.99e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  450 AERSRFEDEKQQLASLIADLQSSVSNLSQAKeeLEQASQAQGAQL-------TAQLTSMT-GLNAtLQQRDQELASLKEQ 521
Cdd:NF012221  1569 ADRQRLEQEKQQQLAAISGSQSQLESTDQNA--LETNGQAQRDAIleesravTKELTTLAqGLDA-LDSQATYAGESGDQ 1645

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  522 AKKEQAQ-MLQTMQEQ-EQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQ-----QLAIVAEAREASLRERD 594
Cdd:NF012221  1646 WRNPFAGgLLDRVQEQlDDAKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQnqanaEQDIDDAKADAEKRKDD 1725

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907176315  595 TARQQLETVEKEKDAKLESLQQQLQAANDARdNAQTSVTQAQQEKAELSQKIGE 648
Cdd:NF012221  1726 ALAKQNEAQQAESDANAAANDAQSRGEQDAS-AAENKANQAQADAKGAKQDESD 1778
PTZ00121 PTZ00121
MAEBL; Provisional
 1144-1653 5.83e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.24  E-value: 5.83e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1144 HSLKSERACRAEQDKALETLQGQLEEKARElgHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLI 1223
Cdd:PTZ00121  1056 HEGKAEAKAHVGQDEGLKPSYKDFDFDAKE--DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA 1133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1224 SSLEEEVSIlnrqvlEKEGESKELKRLVVA-ESEKSQKLEERLRLLQVETASNSARAAERSSAlrEEVQSLRE--EVEKQ 1300
Cdd:PTZ00121  1134 RKAEDARKA------EEARKAEDAKRVEIArKAEDARKAEEARKAEDAKKAEAARKAEEVRKA--EELRKAEDarKAEAA 1205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1301 RVVSENSRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcQQLQAEQAAAEKRFREE 1380
Cdd:PTZ00121  1206 RKAEEERKAEEARKAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF--ARRQAAIKAEEARKADE 1282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1381 LEQSKQAAgglQAELMRAQRELGELGSLRQKiVEQERAAQQLRAEKASYAEQLSMLKKAhgllAEENRGLGERAnlgrqf 1460
Cdd:PTZ00121  1283 LKKAEEKK---KADEAKKAEEKKKADEAKKK-AEEAKKADEAKKKAEEAKKKADAAKKK----AEEAKKAAEAA------ 1348

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1461 leveldqarekyvqelaavrtdaethlaemRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKL--TAQVEELSK 1538
Cdd:PTZ00121  1349 ------------------------------KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAeeKKKADEAKK 1398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1539 KLTEHDQasKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQ 1618
Cdd:PTZ00121  1399 KAEEDKK--KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK 1476

                          490       500       510
                   ....*....|....*....|....*....|....*...
gi 1907176315 1619 DLEELQKENKELRSEAERLGR---ELQQAGLKTKEAEQ 1653
Cdd:PTZ00121  1477 KKAEEAKKADEAKKKAEEAKKkadEAKKAAEAKKKADE 1514
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1146-1652 1.94e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 59.74  E-value: 1.94e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1146 LKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQREL--QALRAKAQDHSKAEEEWKaQVARGQQEAERKsslI 1223
Cdd:pfam05483  160 LKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELrvQAENARLEMHFKLKEDHE-KIQHLEEEYKKE---I 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1224 SSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLlqveTASNSARAAERSSALREEVQSLREEVEKQRVV 1303
Cdd:pfam05483  236 NDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKL----QDENLKELIEKKDHLTKELEDIKMSLQRSMST 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1304 SENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKhlcqqlqaeqaaaekrfREELEQ 1383
Cdd:pfam05483  312 QKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTE-----------------QQRLEK 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1384 SKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEENRGLGERAnlgrqfleV 1463
Cdd:pfam05483  375 NEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAED----EKLLDEKKQFEKIAEELKGKEQEL--------I 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1464 ELDQAREKYVQELaavrtdaETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLE---ERQRFQEERQKLTAQVEELSKKL 1540
Cdd:pfam05483  443 FLLQAREKEIHDL-------EIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIEltaHCDKLLLENKELTQEASDMTLEL 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1541 TEHDQ----ASKVQQQKLKAFQA-------QRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQ 1609
Cdd:pfam05483  516 KKHQEdiinCKKQEERMLKQIENleekemnLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENK 595

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1907176315 1610 NQKLQEQLQD----LEELQKENKELRSEAERLGRELQQAGLKTKEAE 1652
Cdd:pfam05483  596 CNNLKKQIENknknIEELHQENKALKKKGSAENKQLNAYEIKVNKLE 642
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 252-817 2.47e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.42  E-value: 2.47e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  252 MQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS----QLSEENGDLSFKVRE 327
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAarkqELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  328 FANHLQQLQGafndlieEHSKASQEWAEKQARLENELST--ALQ-DKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKG 404
Cdd:pfam01576   87 EEERSQQLQN-------EKKKMQQHIQDLEEQLDEEEAArqKLQlEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  405 EVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQllaeRSRFEDEKQQLASLIADLQSSVSNLSQAKEELE 484
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG----RQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  485 QASQAQGAQLTAQLTSM---TGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkEQQL 561
Cdd:pfam01576  236 AQLAKKEEELQAALARLeeeTAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL---EDTL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  562 EEAAKEQEAtrqdHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 641
Cdd:pfam01576  313 DTTAAQQEL----RSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  642 LSQKIGELHACIEASHQEQRQVQARVTELEAQL-KAEQQKTTEREKVVQEKAQLQEQLRALEE----SLKITK--GSLEE 714
Cdd:pfam01576  389 LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLsESERQRAELAEKLSKLQSELESVSSLLNEaegkNIKLSKdvSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  715 EKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLeeahQAETEALRHELAEATASQHRAE 794
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTL----QAQLSDMKKKLEEDAGTLEALE 544

                          570       580
                   ....*....|....*....|...
gi 1907176315  795 SECERLIREVESRQKRFEARQQE 817
Cdd:pfam01576  545 EGKKRLQRELEALTQQLEEKAAA 567
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 503-619 1.18e-05

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 48.73  E-value: 1.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  503 GLNATLQQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGlRQQVEQLSSSLKLKEQQLEEAAKEQEaTRQDHAQQLAIV 582
Cdd:NF038305    98 HLNNTRRLSTQALQQINQQAGQQETQ-LQQQLNQLQAQTS-PQQLNQLLKSEQKQGQALASGQLPEE-QKEQLQQFKSNP 174

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1907176315  583 AEAREASLRERDTARQQLETVEKEkdAKLESLQQQLQ 619
Cdd:NF038305   175 QALDKFLAQQLTQIRTQAEEAEKQ--ARLEALKSSLR 209
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 577-954 4.47e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.06  E-value: 4.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  577 QQLAIVAEAREASLRERDTARQQ-LETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGElhaciea 655
Cdd:NF012221  1503 KTLKLTAKAGSNRLEFKGTGHNDgLGYILDNVVATSESSQQADAVSKHAKQDDAAQNALADKERAEADRQRLE------- 1575

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  656 shQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGsleeekrraADALKEQQCRATEMEA 735
Cdd:NF012221  1576 --QEKQQQLAAISGSQSQLESTDQNALETNGQAQRDAILEESRAVTKELTTLAQG---------LDALDSQATYAGESGD 1644

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  736 ESRSLMEQR--EREQKELEQEKagrKGLEARIQQLEEAHQAETEALRHELAEATASQHRAesecERLIREVESRQKrfEA 813
Cdd:NF012221  1645 QWRNPFAGGllDRVQEQLDDAK---KISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQG----EQNQANAEQDID--DA 1715

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  814 RQQEEARYGAMFQEQLMALKGEKTGQEVQEEAveihseGQPGQQQSQLAQLHASLAKAiqqvqekevraqklvDDLSALQ 893
Cdd:NF012221  1716 KADAEKRKDDALAKQNEAQQAESDANAAANDA------QSRGEQDASAAENKANQAQA---------------DAKGAKQ 1774

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176315  894 EKMAATNKEVACLKTLVLKAGEQQETA--SLELLKEPPRAAN-RASDQLGEQQGRPFSSTHAAV 954
Cdd:NF012221  1775 DESDKPNRQGAAGSGLSGKAYSVEGVAepGSHINPDSPAAADgRFSEGLTEQEQEALEGATNAV 1838
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 850-1120 1.03e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  850 SEGQpgQQQSQLAQlHASLAKAIQQVQEKEVRA-----------QKLVDDLSALQEKMAATNKEVACLKTLVLKAG--EQ 916
Cdd:NF012221  1538 SESS--QQADAVSK-HAKQDDAAQNALADKERAeadrqrleqekQQQLAAISGSQSQLESTDQNALETNGQAQRDAilEE 1614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  917 QETASLELLKEPPR-AANRASDQLGEQQGRPFSsTHAAVKAMEREAEQM-------GGELERLRAALIKSQGQQQEERGQ 988
Cdd:NF012221  1615 SRAVTKELTTLAQGlDALDSQATYAGESGDQWR-NPFAGGLLDRVQEQLddakkisGKQLADAKQRHVDNQQKVKDAVAK 1693

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  989 QEREVARLTQERGQAQADLAQekaAKAELEMRLQNTLNEQRVefAALQEALAHALTEKegtdqelAKLRGQEAAQRTELK 1068
Cdd:NF012221  1694 SEAGVAQGEQNQANAEQDIDD---AKADAEKRKDDALAKQNE--AQQAESDANAAAND-------AQSRGEQDASAAENK 1761

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176315 1069 ELQQTLEQLKIQLVKKEKEHPAgGASGEDASGPGTQSETAGKTD-APGPELQA 1120
Cdd:NF012221  1762 ANQAQADAKGAKQDESDKPNRQ-GAAGSGLSGKAYSVEGVAEPGsHINPDSPA 1813
TOPEUc smart00435
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ...
 1595-1678 1.53e-03

DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras


Pssm-ID: 214661 [Multi-domain]  Cd Length: 391  Bit Score: 43.11  E-value: 1.53e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  1595 QMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ 1674
Cdd:smart00435  278 SMEKLQEKIKALKYQLKRLKKMILLFEMISDLKRKLKSKFERDNEKLDAEVKEKKKEKKKEEKKKKQIERLEERIEKLEV 357


                    ....
gi 1907176315  1675 QLRD 1678
Cdd:smart00435  358 QATD 361
PRK06975 PRK06975
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
 1552-1740 2.07e-03

bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed


Pssm-ID: 235899 [Multi-domain]  Cd Length: 656  Bit Score: 43.17  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1552 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQaaehyKLQMEKAKThydakkqqnQKLQEQLQDLeeLQKENKELR 1631
Cdd:PRK06975   357 QRQQANDAQTAELRVKTEQAQASVHQLDSQFAQLDG-----KLADAQSAQ---------QALEQQYQDL--SRNRDDWMI 420

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1632 SEAERLgreLQQAGLKTkeaeqtcrHLTAQVRSLEAQVAHADQQLRDLGKFQVAT---------DALKSrepqvKPQLDL 1702
Cdd:PRK06975   421 AEVEQM---LSSASQQL--------QLTGNVQLALIALQNADARLATSDSPQAVAvrkaiaqdiERLKA-----APSADL 484

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1703 S------------IDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASP 1740
Cdd:PRK06975   485 TglaiklddaiakIDALPLSGEALPPHATMAAAPAAAAAAAAAAAAAGEP 534
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.15e-49

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 173.53  E-value: 1.15e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315    6 TRAATLLSWVNSLHVADPVETVLQLQDCSIFIKIINTIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315   86 KVIEG--SEMELAKMIMLFLYQSTMSSRNlrDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNL--TLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 554-1323 1.09e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 122.86  E-value: 1.09e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  554 LKLKEQQlEEAAKEQEATRQDHAQQLAIVAEAREA--SL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 630
Cdd:TIGR02168  168 SKYKERR-KETERKLERTRENLDRLEDILNELERQlkSLeRQAEKAERYKELKAELRELELALLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  631 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLkaeQQKTTEREKVVQEKAQLQEQLRALEESLKITKG 710
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL---YALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  711 SLEEEKRRaadaLKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHqaetEALRHELAEATASQ 790
Cdd:TIGR02168  324 QLEELESK----LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----ETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  791 HRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 870
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  871 AIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASlELLKEPPRAANRASDQLGEQQGRPFSST 950
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAAIEAALGGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  951 -HAAVKAMEREAEQMGG-----ELERLRAALIKSQGQQQEERGQQEREVA-RLTQERGQAQADL---------------A 1008
Cdd:TIGR02168  555 lNAAKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAkDLVKFDPKLRKALsyllggvlvvddldnA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1009 QEKAAKAELEMRLQnTLNEQRVE---FAALQEALAHALTekEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKE 1085
Cdd:TIGR02168  635 LELAKKLRPGYRIV-TLDGDLVRpggVITGGSAKTNSSI--LERRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1086 KEHPAGGASGEDASgpGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQG 1165
Cdd:TIGR02168  712 EELEQLRKELEELS--RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1166 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1245
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1246 ELKRLVVAESEKSQKLEERLRLL--QVETASNSARAAE-RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELG 1322
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY 949


                   .
gi 1907176315 1323 Q 1323
Cdd:TIGR02168  950 S 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 515-1129 8.39e-27

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 119.66  E-value: 8.39e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  515 LASLKEQAKK-EQAQMLQTmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEqeatrqdhaqqlaivAEAREASLRER 593
Cdd:COG1196    202 LEPLERQAEKaERYRELKE-ELKELEAELLLLKLRELEAELEELEAELEELEAE---------------LEELEAELAEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  594 DTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQ 673
Cdd:COG1196    266 EAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  674 LKAEQQkttEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQqcratemeAESRSLMEQREREQKELEQ 753
Cdd:COG1196    346 LEEAEE---ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA--------AELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  754 EKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEarygamfQEQLMALK 833
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL-------AELLEELA 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  834 GEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDD-LSALQEKMAATNKEVACLKTLVLK 912
Cdd:COG1196    488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAaLAAALQNIVVEDDEVAAAAIEYLK 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  913 AGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQERE 992
Cdd:COG1196    568 AAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  993 VARLTQERGQAQADLAQEKAAKaelemrlqntlNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQ 1072
Cdd:COG1196    648 EVTLEGEGGSAGGSLTGGSRRE-----------LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176315 1073 TLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLE 1129
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1852-1910 4.55e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 102.68  E-value: 4.55e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315 1852 LLSLPGYRPTTRSSARRSQarmSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1910
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 412-965 2.21e-24

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 111.95  E-value: 2.21e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  412 QLDTLKQEAAKlATDNTQLQTRVETLECE-RGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQ 490
Cdd:COG1196    201 QLEPLERQAEK-AERYRELKEELKELEAElLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  491 GAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSsLKLKEQQLEEAAKEQEA 570
Cdd:COG1196    280 ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE-LEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  571 TRQDHAQQLAIVAEAREASLRERDTARQQLETVEK---EKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIG 647
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRaaaELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  648 ELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALK--- 724
Cdd:COG1196    439 EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLlag 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  725 ------------------EQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEA 786
Cdd:COG1196    519 lrglagavavligveaayEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIG 598

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  787 TA-SQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLH 865
Cdd:COG1196    599 AAvDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  866 ASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGR 945
Cdd:COG1196    679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPE 758

                          570       580
                   ....*....|....*....|..
gi 1907176315  946 PFSSTHAA--VKAMEREAEQMG 965
Cdd:COG1196    759 PPDLEELEreLERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 330-870 1.63e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 109.26  E-value: 1.63e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  330 NHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGD 409
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  410 ALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQA 489
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  490 QgAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQE 569
Cdd:COG1196    395 A-AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  570 ATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQ---AANDARDNAQTSVTQAQQEKAELSQKI 646
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgavAVLIGVEAAYEAALEAALAAALQNIVV 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  647 GELHACIEASHQEQRQVQARVTEL--EAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALK 724
Cdd:COG1196    554 EDDEVAAAAIEYLKAAKAGRATFLplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  725 EQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQhRAESECERLIREV 804
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL-LAEEEEERELAEA 712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176315  805 ESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 870
Cdd:COG1196    713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 478-1077 1.83e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.87  E-value: 1.83e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  478 QAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMlqtmQEQEQAAQGLRQQVEQLSSSLKLK 557
Cdd:COG1196    211 KAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAEL----AELEAELEELRLELEELELELEEA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  558 EQQLEEAAKEQEATRQD--HAQQLAIVAEAREASL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQ 634
Cdd:COG1196    287 QAEEYELLAELARLEQDiaRLEERRRELEERLEELeEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  635 AQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEE 714
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  715 EKRRAADALKEqqcratemEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAhQAETEALRHELAEATASQHRAE 794
Cdd:COG1196    447 AAEEEAELEEE--------EEALLELLAELLEEAALLEAALAELLEELAEAAARLLL-LLEAEADYEGFLEGVKAALLLA 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  795 SECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALkgektgQEVQEEAVEIHSEGQPGQQQ-SQLAQLHASLAKAIQ 873
Cdd:COG1196    518 GLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED------DEVAAAAIEYLKAAKAGRATfLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  874 QVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEppRAANRASDQLGEQQGrpfSSTHAA 953
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR--LREVTLEGEGGSAGG---SLTGGS 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  954 VKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFA 1033
Cdd:COG1196    667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1907176315 1034 ALQEALAHALTEKEgtdqelaklrgQEAAQRTELKELQQTLEQL 1077
Cdd:COG1196    747 LLEEEALEELPEPP-----------DLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1117-1638 2.60e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.49  E-value: 2.60e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVA-ESEKSQKLEERLRLLQ--VETA 1273
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEaEEELEELAEELLEALRaaAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1274 SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1353
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1354 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL--------------MRAQRELGELGSLRQKIVEQERAA 1419
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavavligveaaYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1420 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQE 1493
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1494 AQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQT 1573
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315 1574 QLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQnqklQEQLQDLEELQKENKELRSEAERLG 1638
Cdd:COG1196    720 ELEEEALEEQLEAEREELLEELLEEEELLEEEALEE----LPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 275-1070 7.40e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.06  E-value: 7.40e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  275 ELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKvrefanhLQQLQGAFNDLIEEHSKASQEWA 354
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE-------IEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  355 EKQARLENelstALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRV 434
Cdd:TIGR02168  306 ILRERLAN----LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  435 ETLECERGKQEAQLLAERSRFedekQQLASLIADLQSSVSNLSQAKEELEQasQAQGAQLTAQLTSMTGLNATLQQRDQE 514
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNEI----ERLEARLERLEDRRERLQQEIEELLK--KLEEAELKELQAELEELEEELEELQEE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  515 LASLKEQAKKEQAQMlqtmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaiVAEAREASLRERD 594
Cdd:TIGR02168  456 LERLEEALEELREEL----EEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKA--------LLKNQSGLSGILG 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  595 TARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKA-------ELS----QKIGELHACIEASHQEQRQV 663
Cdd:TIGR02168  524 VLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNElgrvtflPLDsikgTEIQGNDREILKNIEGFLGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  664 QARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKI--------TKGSLEEEKRRAADALkeQQCRATEMEa 735
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIvtldgdlvRPGGVITGGSAKTNSS--ILERRREIE- 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  736 ESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQ 815
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  816 QEEARYGAMFQEQLMALKGEKTGQEVQEEAVEihsegqpgQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEK 895
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIE--------QLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  896 MAATNKEVACLKTLVLKAGEQQETASLEL--LKEPPRAANRASDQLGEQqgrpFSSTHAAVKAMEREAEQMGGELERLRa 973
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIeeLEELIEELESELEALLNE----RASLEEALALLRSELEELSEELRELE- 907

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  974 aliksqgqqqeergqqeREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEalaHALTEKEGTDQEL 1053
Cdd:TIGR02168  908 -----------------SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE---EAEALENKIEDDE 967

                          810
                   ....*....|....*..
gi 1907176315 1054 AKLRGQEAAQRTELKEL 1070
Cdd:TIGR02168  968 EEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 207-907 8.69e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.06  E-value: 8.69e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  207 LQTPQFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRI-DHLALLNEKQAASSQEPSELEELRGKNES 285
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyALANEISRLEQQKQILRERLANLERQLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  286 LTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAE---KQARLEN 362
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQlelQIASLNN 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  363 ELSTALQDKKCLEEKNEILQGKLSQLEDQatrlqespaPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERG 442
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKK---------LEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  443 KQEAQLLAERSRFEDEKQQLASL-----------------------IADLQSSVSNLSQAKEELEQA-SQAQGAQLTAQL 498
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLerlqenlegfsegvkallknqsgLSGILGVLSELISVDEGYEAAiEAALGGRLQAVV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  499 TSmtglnaTLQQRDQELASLKeQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQ 578
Cdd:TIGR02168  552 VE------NLNAAKKAIAFLK-QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGG 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  579 LAIVAEAREA-SLRERDTARQQLETVEKEKDAKLESLqqqlqaaNDARDNAQTSVTQAQQEKAELSQKIGELhacieash 657
Cdd:TIGR02168  625 VLVVDDLDNAlELAKKLRPGYRIVTLDGDLVRPGGVI-------TGGSAKTNSSILERRREIEELEEKIEEL-------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  658 qeqrqvQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAES 737
Cdd:TIGR02168  690 ------EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  738 RSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETE---ALRHELAEATASQHRAESECERLIREVESRQKRFEAR 814
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  815 QQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEgQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQE 894
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLN-ERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          730
                   ....*....|...
gi 1907176315  895 KMAATNKEVACLK 907
Cdd:TIGR02168  923 KLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 553-1324 1.08e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 106.68  E-value: 1.08e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  553 SLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSV 632
Cdd:TIGR02168  204 SLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEI 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  633 TQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREK----VVQEKAQLQEQLRALEESLKIT 708
Cdd:TIGR02168  284 EELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEelaeLEEKLEELKEELESLEAELEEL 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  709 KGSLEEEKRRAAD---ALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE-EAHQAETEALRHELA 784
Cdd:TIGR02168  364 EAELEELESRLEEleeQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLkKLEEAELKELQAELE 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  785 EATASQHRAESECERLIREVESRQKRFEARQQEEARygamFQEQLMALKGEKTGQEVQEEAVEIHSEG--QPGQQQSQLA 862
Cdd:TIGR02168  444 ELEEELEELQEELERLEEALEELREELEEAEQALDA----AERELAQLQARLDSLERLQENLEGFSEGvkALLKNQSGLS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  863 QLHASLAKAIQQVQEKEV--------RAQKLVDDLSALQEKMAATNKEVACLKTLVL------------------KAGEQ 916
Cdd:TIGR02168  520 GILGVLSELISVDEGYEAaieaalggRLQAVVVENLNAAKKAIAFLKQNELGRVTFLpldsikgteiqgndreilKNIEG 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  917 QETASLELLKEPPRA-------------------ANRASDQL----------GEQQGRPFSSTHAAVKA----MEREAEQ 963
Cdd:TIGR02168  600 FLGVAKDLVKFDPKLrkalsyllggvlvvddldnALELAKKLrpgyrivtldGDLVRPGGVITGGSAKTnssiLERRREI 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  964 mgGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRvefaALQEALAHAL 1043
Cdd:TIGR02168  680 --EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE----QLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1044 TEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKiQLVKKEKEhpaggasgedasgpgtqsetagktdapgpELQALRA 1123
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELE-AQIEQLKE-----------------------------ELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1124 EISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEE 1203
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1204 EWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELK----RLVVAESEKSQKLEERLRLLQVETASNSARA 1279
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLElrleGLEVRIDNLQERLSEEYSLTLEEAEALENKI 963

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*
gi 1907176315 1280 AERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQE 1324
Cdd:TIGR02168  964 EDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQ 1008
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 213-903 2.15e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 102.44  E-value: 2.15e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  213 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHL-----ALLNEKQAASSQE---PSELEELRGKNE 284
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkelyALANEISRLEQQKqilRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  285 SLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAE---KQARLE 361
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQlelQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  362 NELSTALQDKKCLEEKNEILQGKLSQLEDQatrlqespaPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECER 441
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKK---------LEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  442 GKQEAQLLAERSRFEDEKQQLASL-----------------------IADLQSSVSNLSQAKEELEQA-SQAQGAQLTAQ 497
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLerlqenlegfsegvkallknqsgLSGILGVLSELISVDEGYEAAiEAALGGRLQAV 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  498 LtsMTGLNATLQ--------------------QRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKL- 556
Cdd:TIGR02168  551 V--VENLNAAKKaiaflkqnelgrvtflpldsIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVv 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  557 ------KEQQLEEAAKEQEATRQDH--AQQLAIVAEAREASL------RERDTARQQLETVE---KEKDAKLESLQQQLQ 619
Cdd:TIGR02168  629 ddldnaLELAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSsilerrREIEELEEKIEELEekiAELEKALAELRKELE 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  620 AANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTE-----------REKVV 688
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeelaeaeaeIEELE 788

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  689 QEKAQLQEQLRALEESLKITKGSLEEEKRRAADA----------LKEQQCRATEMEAESRSLMEQREREQKELEQEKAGR 758
Cdd:TIGR02168  789 AQIEQLKEELKALREALDELRAELTLLNEEAANLrerleslerrIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  759 KGLEARIQQLEE---AHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMAL--K 833
Cdd:TIGR02168  869 EELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLseE 948

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  834 GEKTGQEVQEEAVEIhsEGQPGQQQSQLAQLHASLAK-------AIQQVQEKEVR-----AQK--LVDDLSALQEKMAAT 899
Cdd:TIGR02168  949 YSLTLEEAEALENKI--EDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELKERydfltAQKedLTEAKETLEEAIEEI 1026


                   ....
gi 1907176315  900 NKEV 903
Cdd:TIGR02168 1027 DREA 1030
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1117-1622 5.38e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 100.78  E-value: 5.38e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNS 1276
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1277 ARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1356
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1357 LPAKHLcqQLQAEQAAAEKRFREELEQSKQAAGGLQAEL-----MRAQRELGELGSLRQKIVEQERAAQQ----LRAEKA 1427
Cdd:COG1196    494 LLLLEA--EADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaaYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKA 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1428 SYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMT 1505
Cdd:COG1196    572 GRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1506 ----------AKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQL 1575
Cdd:COG1196    651 legeggsaggSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315 1576 NELQAQLSQKEQAAEHYKLQMEKAKTH--------------------------------YDAKKQQNQKLQEQLQDLEE 1622
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPeppdleelerelerlereiealgpvnllaieeYEELEERYDFLSEQREDLEE 809
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 856-1626 8.53e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.52  E-value: 8.53e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  856 QQQSQLAQLHASLakaiqQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLvLKAGEQQETASLELLKEPPRAANRA 935
Cdd:TIGR02168  206 ERQAEKAERYKEL-----KAELRELELALLVLRLEELREELEELQEELKEAEEE-LEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  936 SDQLGEQQGRPFSSThAAVKAMEREAEQMGGELERLRAaliksqgqqqeERGQQEREVARLTQERGQAQADLAQEKAAKA 1015
Cdd:TIGR02168  280 EEEIEELQKELYALA-NEISRLEQQKQILRERLANLER-----------QLEELEAQLEELESKLDELAEELAELEEKLE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1016 ELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQ---ELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGG 1092
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESRLEELEEQLETlrsKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELL 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1093 ASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDkALETLQGQLEEKAR 1172
Cdd:TIGR02168  428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD-SLERLQENLEGFSE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1173 ELghnqAASASAQRELQALRAKAQDHSKAEEEWKA------------------QVARGQQEAERKSSLI-SSLEEEVSIL 1233
Cdd:TIGR02168  507 GV----KALLKNQSGLSGILGVLSELISVDEGYEAaieaalggrlqavvvenlNAAKKAIAFLKQNELGrVTFLPLDSIK 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1234 NRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL------QVETASNSARAAERSSALREE---VQSLREEVEKQRVVS 1304
Cdd:TIGR02168  583 GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllgGVLVVDDLDNALELAKKLRPGyriVTLDGDLVRPGGVIT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1305 ENSRQELASQAERA---EELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEL 1381
Cdd:TIGR02168  663 GGSAKTNSSILERRreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1382 EQSKQAAGGLQAELMRAQRE----LGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLG 1457
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEieelEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1458 RQFLEVELDQAR--EKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAkvkvLEERQRFQEERQKLTAQVEE 1535
Cdd:TIGR02168  823 RERLESLERRIAatERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERASLEEALALLRSELEE 898

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1536 LSKKLTEHDqaskvqqQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQ-KEQAAEHYKLQMEKAKTHYDAKKQQNQKLQ 1614
Cdd:TIGR02168  899 LSEELRELE-------SKRSELRRELEELREKLAQLELRLEGLEVRIDNlQERLSEEYSLTLEEAEALENKIEDDEEEAR 971

                          810
                   ....*....|..
gi 1907176315 1615 EQLQDLEELQKE 1626
Cdd:TIGR02168  972 RRLKRLENKIKE 983
PTZ00121 PTZ00121
MAEBL; Provisional
 265-937 1.23e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 100.22  E-value: 1.23e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  265 KQAASSQEPSELEELRGKNESLTV----RLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAfn 340
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAeavkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-- 1280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  341 dliEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKlSQLEDQATRLQEspAPEKGEVLGDALQLDTLKQEA 420
Cdd:PTZ00121  1281 ---DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK-KKAEEAKKKADA--AKKKAEEAKKAAEAAKAEAEA 1354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  421 AKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTS 500
Cdd:PTZ00121  1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  501 MTGLNATLQQRDQELASLKEQAKKeqAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLA 580
Cdd:PTZ00121  1435 EAKKKAEEAKKADEAKKKAEEAKK--AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA 1512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  581 ivAEAREAS-LRERDTARQQLETVEKEKDAKLESLQQ--QLQAANDARDNAQtsVTQAQQEKAELSQKIGELHACIEASH 657
Cdd:PTZ00121  1513 --DEAKKAEeAKKADEAKKAEEAKKADEAKKAEEKKKadELKKAEELKKAEE--KKKAEEAKKAEEDKNMALRKAEEAKK 1588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  658 QEQRQVQA--RVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKgslEEEKRRAADALKEQQCRATEMEA 735
Cdd:PTZ00121  1589 AEEARIEEvmKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE---AEEKKKAEELKKAEEENKIKAAE 1665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  736 ESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQ 815
Cdd:PTZ00121  1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  816 QEEARYGAMFQEQLMALKG--EKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKA---IQQVQEKEVRAQKLVDDls 890
Cdd:PTZ00121  1746 AEEAKKDEEEKKKIAHLKKeeEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnFANIIEGGKEGNLVIND-- 1823

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 1907176315  891 aLQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASD 937
Cdd:PTZ00121  1824 -SKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEAD 1869
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 665-1639 1.42e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.75  E-value: 1.42e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  665 ARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKgslEEEKRRAADALKEQQCRATEMEAESRSLMEQR 744
Cdd:TIGR02168  189 DRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLR---LEELREELEELQEELKEAEEELEELTAELQEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  745 EREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAM 824
Cdd:TIGR02168  266 EEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  825 FQEqlmaLKGEKTGQEvqeeaveihsegqpgqqqSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVA 904
Cdd:TIGR02168  346 LEE----LKEELESLE------------------AELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  905 CLKTLVLKAGEQQEtaslellkeppRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKsqgqqqe 984
Cdd:TIGR02168  404 RLEARLERLEDRRE-----------RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEE------- 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  985 ergqQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEAlaHALTEKEGTDQELAKLR-GQEAAQ 1063
Cdd:TIGR02168  466 ----LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ--SGLSGILGVLSELISVDeGYEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1064 RTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTqsetagktDAPGPELQALRAEISKleqqcqqqqqQVEGLT 1143
Cdd:TIGR02168  540 EAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLD--------SIKGTEIQGNDREILK----------NIEGFL 601

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1144 HSLKSERACRAEQDKALETLQGQLeekarelgHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSli 1223
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSYLLGGV--------LVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS-- 671

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1224 ssleeevsILNRQvlekegesKELKRLvvaeSEKSQKLEERLRLLQVETAsnsaraaerssALREEVQSLREEVEKQRVV 1303
Cdd:TIGR02168  672 --------ILERR--------REIEEL----EEKIEELEEKIAELEKALA-----------ELRKELEELEEELEQLRKE 720

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1304 SENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQ 1383
Cdd:TIGR02168  721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1384 SKQAAGGLQAELMRaqrelgelgsLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEnrglgeranlgrqflev 1463
Cdd:TIGR02168  801 LREALDELRAELTL----------LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED----------------- 853

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1464 eldqarekyVQELAAVRTDAETHLAEMRQEAQStsrelevmtakyegakvkVLEERQRFQEERQKLTAQVEELSKKLTEH 1543
Cdd:TIGR02168  854 ---------IESLAAEIEELEELIEELESELEA------------------LLNERASLEEALALLRSELEELSEELREL 906

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1544 DQaskvqqqKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQ-KEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLqdlee 1622
Cdd:TIGR02168  907 ES-------KRSELRRELEELREKLAQLELRLEGLEVRIDNlQERLSEEYSLTLEEAEALENKIEDDEEEARRRL----- 974

                          970
                   ....*....|....*..
gi 1907176315 1623 lqkenKELRSEAERLGR 1639
Cdd:TIGR02168  975 -----KRLENKIKELGP 986
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 213-814 1.97e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.24  E-value: 1.97e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  213 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALlnekqaassqepsELEELRGKNESLTVRLHE 292
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  293 TLKQCQNLKTEKSQMDRKISQLSEENgdlsfkvrefanhlqqlqgafndlieehskasQEWAEKQARLENELSTALQDKK 372
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEEL--------------------------------AELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  373 CLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLEcergKQEAQLLAER 452
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  453 SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQT 532
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  533 MQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLE 612
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  613 SLQ-QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashqeqrqVQARVTELEAQLKAEQQKTTEREKVVQEK 691
Cdd:COG1196    584 ARAaLAAALARGAIGAAVDLVASDLREADARYYVLGDTLL-----------GRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  692 AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 771
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907176315  772 HQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEAR 814
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1119-1681 8.41e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.93  E-value: 8.41e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1119 QALRAEISKLEqqcqqqqqqVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDH 1198
Cdd:COG1196    216 RELKEELKELE---------AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1199 SKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSAR 1278
Cdd:COG1196    287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1279 AAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP 1358
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1359 AKHLCQQLQAEQAAAEKRFREELEQSKQAagglQAELMRAQRELGELGSlRQKIVEQERAAQQLRAEKASYAEQLSMLKK 1438
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALL----EAALAELLEELAEAAA-RLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1439 AHGLLAEENRG-------LGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHL---AEMRQEAQSTSRELEVMTAKY 1508
Cdd:COG1196    522 LAGAVAVLIGVeaayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLpldKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1509 EGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQ-------QEVQRLQTQLNELQAQ 1581
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAggsltggSRRELLAALLEAEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1582 LSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQ 1661
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                          570       580
                   ....*....|....*....|
gi 1907176315 1662 VRSLEAQVAHADQQLRDLGK 1681
Cdd:COG1196    762 LEELERELERLEREIEALGP 781
PTZ00121 PTZ00121
MAEBL; Provisional
 653-1432 1.62e-19

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 96.36  E-value: 1.62e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  653 IEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEE------KRRAADALKEQ 726
Cdd:PTZ00121  1052 IDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEArkaeeaKKKAEDARKAE 1131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  727 QCRATEmeaESRSLMEQREREqkELEQEKAGRKGLEARiqQLEEAHQAEtEALRHELAEATASQHRAESecerlIREVES 806
Cdd:PTZ00121  1132 EARKAE---DARKAEEARKAE--DAKRVEIARKAEDAR--KAEEARKAE-DAKKAEAARKAEEVRKAEE-----LRKAED 1198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  807 RQKRFEARQQEEARYGAMFQEQLMALKGE--KTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQK 884
Cdd:PTZ00121  1199 ARKAEAARKAEEERKAEEARKAEDAKKAEavKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEAR 1278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  885 LVDDLSALQEKMAATNKEvaclktlvlKAGEQQETASLELLKEPPRAANRASDQLGEQQGRpfssthaaVKAMEREAEQM 964
Cdd:PTZ00121  1279 KADELKKAEEKKKADEAK---------KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKK--------ADAAKKKAEEA 1341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  965 GGELERLRAAliKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAkaelEMRLQNTLNEQRVEFAALQEALAHALT 1044
Cdd:PTZ00121  1342 KKAAEAAKAE--AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAE----EKKKADEAKKKAEEDKKKADELKKAAA 1415

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1045 EKEGTDQelAKLRGQEAAQRTELKelQQTLEQLKIQLVKKEKEHpagGASGEDASGPGTQSETAGKTDAPGPELQALRAE 1124
Cdd:PTZ00121  1416 AKKKADE--AKKKAEEKKKADEAK--KKAEEAKKADEAKKKAEE---AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA 1488

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1125 ISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARElghnQAASASAQRELQALRaKAQDHSKAEEE 1204
Cdd:PTZ00121  1489 KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAD----EAKKAEEKKKADELK-KAEELKKAEEK 1563

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1205 WKAQVARgqQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQklEERLRLLQVETASNSARAAERSS 1284
Cdd:PTZ00121  1564 KKAEEAK--KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE--EAKIKAEELKKAEEEKKKVEQLK 1639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1285 ALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQAL----VSELLPAK 1360
Cdd:PTZ00121  1640 KKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELkkkeAEEKKKAE 1719

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176315 1361 HLCQQLQAEQAAAEKRFREELEQSKQAAgglqaelmRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQ 1432
Cdd:PTZ00121  1720 ELKKAEEENKIKAEEAKKEAEEDKKKAE--------EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
PTZ00121 PTZ00121
MAEBL; Provisional
 959-1652 6.23e-19

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 94.44  E-value: 6.23e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  959 REAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTlneQRVEFAALQEA 1038
Cdd:PTZ00121  1104 KKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEA---RKAEDAKKAEA 1180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1039 LAHALTEKEGTDQELAK-LRGQEAAQRTE----LKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDA 1113
Cdd:PTZ00121  1181 ARKAEEVRKAEELRKAEdARKAEAARKAEeerkAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEA 1260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1114 PGPELQALRAEISKLEQQCQQQQQQVEgltHSLKSERACRAEQDKALETLQGQLEEKaRELGHNQAASASAQRELQALRA 1193
Cdd:PTZ00121  1261 RMAHFARRQAAIKAEEARKADELKKAE---EKKKADEAKKAEEKKKADEAKKKAEEA-KKADEAKKKAEEAKKKADAAKK 1336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1194 KAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvAESEKSQKLEERLRLLQVETA 1273
Cdd:PTZ00121  1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK---ADEAKKKAEEDKKKADELKKA 1413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1274 SNSARAAERSSALREEVQSLREEVEKQrvvsensrqELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1353
Cdd:PTZ00121  1414 AAAKKKADEAKKKAEEKKKADEAKKKA---------EEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK 1484

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1354 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRElgelgslRQKIVEQERAAQQLRAEKASYAEQL 1433
Cdd:PTZ00121  1485 ADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEE-------AKKADEAKKAEEKKKADELKKAEEL 1557

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1434 SmlKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKV 1513
Cdd:PTZ00121  1558 K--KAEEKKKAEEAKKAEEDKNMALRKAE-EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKK 1634

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1514 KVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQqevqrlqtqlnelqaqlsqKEQAAEHYK 1593
Cdd:PTZ00121  1635 VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEED-------------------EKKAAEALK 1695

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315 1594 LQMEKAKTHYDAKKqqnqKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAE 1652
Cdd:PTZ00121  1696 KEAEEAKKAEELKK----KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 519-1315 2.83e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 92.05  E-value: 2.83e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  519 KEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQ 598
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  599 QLETVEKEKDAK---LESLQQQLQAANdARDNAQTSVTQA--QQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQ 673
Cdd:TIGR02169  252 ELEKLTEEISELekrLEEIEQLLEELN-KKIKDLGEEEQLrvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  674 LKAEQQKTTEREKVVQE----KAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEA----------ESRS 739
Cdd:TIGR02169  331 IDKLLAEIEELEREIEEerkrRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKlkreinelkrELDR 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  740 LMEQREREQKELEQEKAGRKGLEARIQQLE---EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQ 816
Cdd:TIGR02169  411 LQEELQRLSEELADLNAAIAGIEAKINELEeekEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  817 EEARYGAmfqeQLMALKGEKTGQEVQEEAVEIHSEGQPGqQQSQLAQLHASLAKAIQQVQEKevRAQKLVDDLSALQEKM 896
Cdd:TIGR02169  491 ELAEAEA----QARASEERVRGGRAVEEVLKASIQGVHG-TVAQLGSVGERYATAIEVAAGN--RLNNVVVEDDAVAKEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  897 AATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLG-EQQGRP-----FSSThAAVKAMEREAEQMGG-ELE 969
Cdd:TIGR02169  564 IELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEfDPKYEPafkyvFGDT-LVVEDIEAARRLMGKyRMV 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  970 RLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEmRLQNTLNEQRVEFAALQEALAHALTEKEGT 1049
Cdd:TIGR02169  643 TLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELS-SLQSELRRIENRLDELSQELSDASRKIGEI 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1050 DQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpaggasgedasgpgtQSETAGKTDAPGPELQALRAEISKLE 1129
Cdd:TIGR02169  722 EKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE----------------LKELEARIEELEEDLHKLEEALNDLE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1130 qqCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQV 1209
Cdd:TIGR02169  786 --ARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1210 ARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREE 1289
Cdd:TIGR02169  864 EELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGED 943

                          810       820
                   ....*....|....*....|....*.
gi 1907176315 1290 VQSLREEVEKQRVVSENSRQELASQA 1315
Cdd:TIGR02169  944 EEIPEEELSLEDVQAELQRVEEEIRA 969
PTZ00121 PTZ00121
MAEBL; Provisional
 562-1324 2.98e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 92.51  E-value: 2.98e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  562 EEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARqqLETVEKEKDAKleSLQQQLQAANDARDNAQTSVTQAQQ---- 637
Cdd:PTZ00121  1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARK--AEEARKAEDAR--KAEEARKAEDAKRVEIARKAEDARKaeea 1169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  638 EKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKR 717
Cdd:PTZ00121  1170 RKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEER 1249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  718 RAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEAR----IQQLEEAHQAETEALRHElaEATASQHRA 793
Cdd:PTZ00121  1250 NNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKkaeeKKKADEAKKKAEEAKKAD--EAKKKAEEA 1327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  794 ESECERLIREVESRQKRFEA-RQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAI 872
Cdd:PTZ00121  1328 KKKADAAKKKAEEAKKAAEAaKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKA 1407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  873 QQVQEKEVRAQKlvddlsalQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSTHA 952
Cdd:PTZ00121  1408 DELKKAAAAKKK--------ADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKA 1479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  953 AVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEF 1032
Cdd:PTZ00121  1480 EEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKK 1559

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1033 AALQEALAHALTEKEGTDQELAK---LRGQEAAQRTELKELQQTLEQLKIQLVKKEkehpaggasgEDASGPGTQSETAG 1109
Cdd:PTZ00121  1560 AEEKKKAEEAKKAEEDKNMALRKaeeAKKAEEARIEEVMKLYEEEKKMKAEEAKKA----------EEAKIKAEELKKAE 1629

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1110 KTDAPGPELQALRAEisklEQQCQQQQQQVEGLTHSLKSERACRAEQDKaletlqgqleEKARELghnQAASASAQRELQ 1189
Cdd:PTZ00121  1630 EEKKKVEQLKKKEAE----EKKKAEELKKAEEENKIKAAEEAKKAEEDK----------KKAEEA---KKAEEDEKKAAE 1692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1190 ALRAKAQDHSKAEeewkaQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEErlrLLQ 1269
Cdd:PTZ00121  1693 ALKKEAEEAKKAE-----ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAH---LKK 1764

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315 1270 VETASNSARAAERSSALREEVqslREEVEKQRVVSENSRQELASQAERAEELGQE 1324
Cdd:PTZ00121  1765 EEEKKAEEIRKEKEAVIEEEL---DEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1003-1681 3.15e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 3.15e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1003 AQADLAQEKAAKAELEMRLqNTLNEQR---VEFAALQEALAHA-----LTEKEGTDQELAKLRGQEAAQRTELKELQQTL 1074
Cdd:TIGR02168  184 TRENLDRLEDILNELERQL-KSLERQAekaERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1075 EQLKIQLVKKEKEHPAGGASGEDASGpgtqsetagktdapgpELQALRAEISKLEQQCQQQQQQVEGLTHSLKseracra 1154
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQK----------------ELYALANEISRLEQQKQILRERLANLERQLE------- 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1155 EQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILN 1234
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1235 rqvlekegeskelKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQ 1314
Cdd:TIGR02168  400 -------------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1315 AERAEELGQELKAWQEKFFQKEQ---ALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKrFREELEQSKQAAGG- 1390
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALGg 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1391 -LQAELMR------------AQRELG-------------ELGSLRQKIVEQERAAQQLRAEKASYAEQLSM--------- 1435
Cdd:TIGR02168  546 rLQAVVVEnlnaakkaiaflKQNELGrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggv 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1436 -----LKKAHGLLAEENRGL-------------------GERANLGRQFLEVELDQAREKY-------------VQELAA 1478
Cdd:TIGR02168  626 lvvddLDNALELAKKLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIeeleekiaelekaLAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1479 VRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKV---LEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLK 1555
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVeqlEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1556 AFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAE 1635
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176315 1636 RLGRELQ---QAGLKTKEAEQTCRH--------LTAQVRSLEAQVAHADQQLRDLGK 1681
Cdd:TIGR02168  866 ELIEELEselEALLNERASLEEALAllrseleeLSEELRELESKRSELRRELEELRE 922
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 211-844 3.62e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 3.62e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  211 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPS--------ELEELRGK 282
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELEsrleeleeQLETLRSK 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  283 NESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANH------------LQQLQGAFNDLIEEHSKAS 350
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelqaeleeleeeLEELQEELERLEEALEELR 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  351 QEWAEKQARL---ENELSTALQDKKCLEEKNEILQG----------KLSQLEDQATRLQESPAPEKG------EVLGDAL 411
Cdd:TIGR02168  468 EELEEAEQALdaaERELAQLQARLDSLERLQENLEGfsegvkallkNQSGLSGILGVLSELISVDEGyeaaieAALGGRL 547

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  412 Q-------------LDTLKQEAAKLATD---NTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSN 475
Cdd:TIGR02168  548 QavvvenlnaakkaIAFLKQNELGRVTFlplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  476 LSQAKEELEQASQAQGAQLTAQLT--------SMTG----LNATLQQRDQELASLKEQakkeQAQMLQTMQEQEQAAQGL 543
Cdd:TIGR02168  628 VDDLDNALELAKKLRPGYRIVTLDgdlvrpggVITGgsakTNSSILERRREIEELEEK----IEELEEKIAELEKALAEL 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  544 RQQVEQLSSSLKLKEQQLEEAAKEQEATRQDhAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND 623
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  624 ARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQ-----------QKTTEREKVVQEKA 692
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATErrledleeqieELSEDIESLAAEIE 862

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  693 QLQEQLRALE---ESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE 769
Cdd:TIGR02168  863 ELEELIEELEselEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  770 EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRF--------EARQQEEARYGAMFQEQLMALKGEKTGQEV 841
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022


                   ...
gi 1907176315  842 QEE 844
Cdd:TIGR02168 1023 IEE 1025
PTZ00121 PTZ00121
MAEBL; Provisional
 343-1072 1.17e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 87.12  E-value: 1.17e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  343 IEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLedqATRLQESPAPEKGEVLGDALQLDTLKQEAAK 422
Cdd:PTZ00121  1111 AEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEI---ARKAEDARKAEEARKAEDAKKAEAARKAEEV 1187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  423 LATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQlasliadlqSSVSNLSQAKEELEQASQAQGAQLTAQLTSMT 502
Cdd:PTZ00121  1188 RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKA---------EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFE 1258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  503 GLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGL-RQQVEQLSSslKLKEQQLEEAAKEQEATRQDHAQQLAI 581
Cdd:PTZ00121  1259 EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEeKKKADEAKK--KAEEAKKADEAKKKAEEAKKKADAAKK 1336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  582 VAE----AREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQtsvtqaQQEKAELSQKIGELHAciEASH 657
Cdd:PTZ00121  1337 KAEeakkAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAE------EKKKADEAKKKAEEDK--KKAD 1408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  658 QEQRQVQARVTELEAQLKAEQ-QKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAE 736
Cdd:PTZ00121  1409 ELKKAAAAKKKADEAKKKAEEkKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA 1488

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  737 SRSLMEQREREQKELEQEKAGRKGLEAR----IQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFE 812
Cdd:PTZ00121  1489 KKKAEEAKKKADEAKKAAEAKKKADEAKkaeeAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEE 1568

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  813 ARQQEEARYGAMFQEQLMalkgeKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSAL 892
Cdd:PTZ00121  1569 AKKAEEDKNMALRKAEEA-----KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA 1643

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  893 QEKMAATN----KEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLG--EQQGRPFSSTHAAVKAMEREAEQMGG 966
Cdd:PTZ00121  1644 EEKKKAEElkkaEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKkeAEEAKKAEELKKKEAEEKKKAEELKK 1723

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  967 ELE---------RLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVE------ 1031
Cdd:PTZ00121  1724 AEEenkikaeeaKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDkkikdi 1803

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907176315 1032 ---FAALQEA----LAHALTEKEGTDQELAKLRGQEAAQRTELKELQQ 1072
Cdd:PTZ00121  1804 fdnFANIIEGgkegNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEK 1851
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 954-1665 9.78e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 9.78e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  954 VKAMEREAEQMGGELERLRAA---LIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQ---NTLNE 1027
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEvseLEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEeleSKLDE 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1028 QRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpaggasgedasgpgtqset 1107
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ-------------------- 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1108 agktdapgpeLQALRAEISKLEQQCQQQQQQVEGLTHSLKSERacRAEQDKALETLQGQLEEKARELGHNQAASASAQRE 1187
Cdd:TIGR02168  395 ----------IASLNNEIERLEARLERLEDRRERLQQEIEELL--KKLEEAELKELQAELEELEEELEELQEELERLEEA 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1188 LQALRAKAQDHSKAEEEWKAQVARGQQEAErksslissleeevsILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRL 1267
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQARLD--------------SLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1268 LQVETASNSARAAerssALREEVQSLreevekqrVVSENSRQELASQAERAEELGQ----ELKAWQEKFFQKEQALSALQ 1343
Cdd:TIGR02168  529 ISVDEGYEAAIEA----ALGGRLQAV--------VVENLNAAKKAIAFLKQNELGRvtflPLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1344 LEHTSTQALVSELLPAK-HLCQQLQAEQAAAEKRFREELEQSKQAAGG-----LQAELMR---------AQRELG----- 1403
Cdd:TIGR02168  597 IEGFLGVAKDLVKFDPKlRKALSYLLGGVLVVDDLDNALELAKKLRPGyrivtLDGDLVRpggvitggsAKTNSSilerr 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1404 -ELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVEldqarEKYVQELAAVRTD 1482
Cdd:TIGR02168  677 rEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL-----EAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1483 AETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVL---EERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQA 1559
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEeleAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1560 QRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQ-----------DLEELQKENK 1628
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAllrseleelseELRELESKRS 911

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 1907176315 1629 ELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSL 1665
Cdd:TIGR02168  912 ELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE 948
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 244-894 2.04e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 2.04e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  244 EKDAQIAMMQQRIDHLAL-LNEKQAASSQEPSELEELrGKNESLTVR-----LHETLKQCQN----LKTEKSQMDRKISQ 313
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKrLEEIEQLLEELNKKIKDL-GEEEQLRVKekigeLEAEIASLERsiaeKERELEDAEERLAK 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  314 LSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLEN---ELSTALQDKKCLEEKNEILQGKLSQLED 390
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEvdkEFAETRDELKDYREKLEKLKREINELKR 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  391 QATRLQESPAPEKGEVLgdalqldTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQ 470
Cdd:TIGR02169  407 ELDRLQEELQRLSEELA-------DLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYD 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  471 SSVSNLSQAKEELEQASQAQGAQLTAQLTS-------------MTGLNATLQQRDQELASLKEQA--KKEQAQMLQTMQE 535
Cdd:TIGR02169  480 RVEKELSKLQRELAEAEAQARASEERVRGGraveevlkasiqgVHGTVAQLGSVGERYATAIEVAagNRLNNVVVEDDAV 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  536 QEQAAQGLR---------------QQVEQLSSSLKLK------------EQQLEEAAK---------EQEATRQDHAQQL 579
Cdd:TIGR02169  560 AKEAIELLKrrkagratflplnkmRDERRDLSILSEDgvigfavdlvefDPKYEPAFKyvfgdtlvvEDIEAARRLMGKY 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  580 --------------AIVAEAREASLRERDTARQQLEtvEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQK 645
Cdd:TIGR02169  640 rmvtlegelfeksgAMTGGSRAPRGGILFSRSEPAE--LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK 717

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  646 IGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTT----EREKVVQEKAQLQEQLRALEESLKITKGSL--------E 713
Cdd:TIGR02169  718 IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEnvksELKELEARIEELEEDLHKLEEALNDLEARLshsripeiQ 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  714 EEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARI---QQLEEAHQAETEALRHELAEATASQ 790
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIksiEKEIENLNGKKEELEEELEELEAAL 877

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  791 HRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEavEIHSEGQPGQQQSQLAQLHASLAK 870
Cdd:TIGR02169  878 RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE--ELSEIEDPKGEDEEIPEEELSLED 955

                          730       740
                   ....*....|....*....|....*
gi 1907176315  871 AIQQVQEKEVRAQKLVD-DLSALQE 894
Cdd:TIGR02169  956 VQAELQRVEEEIRALEPvNMLAIQE 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1051-1679 7.42e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.80  E-value: 7.42e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1051 QELAKLRGqEAAQRTELKELQQTLEQLKIQLVKKEKEhpaggasGEDASGPGTQSETAGKTDapgpELQALRAEISKLEQ 1130
Cdd:TIGR02169  198 QQLERLRR-EREKAERYQALLKEKREYEGYELLKEKE-------ALERQKEAIERQLASLEE----ELEKLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1131 QCQQQQQQVEGLTHSLKSERACRAEQDKA--------LETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAE 1202
Cdd:TIGR02169  266 RLEEIEQLLEELNKKIKDLGEEEQLRVKEkigeleaeIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREI 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1203 EEWKAQVARGQQEaerksslISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAER 1282
Cdd:TIGR02169  346 EEERKRRDKLTEE-------YAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRL 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1283 SSA---LREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPA 1359
Cdd:TIGR02169  419 SEEladLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1360 KhlcqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQR------ELGELGSLRQKIVEQERAAQQ----LRAEKASY 1429
Cdd:TIGR02169  499 A----RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGEryataiEVAAGNRLNNVVVEDDAVAKEaielLKRRKAGR 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1430 AEQLSMLKKAHGLLaeENRGLGERANLGRQFLEVELDQARE---KYVQELAAVRTDAETHLAEMRQEAQST--------- 1497
Cdd:TIGR02169  575 ATFLPLNKMRDERR--DLSILSEDGVIGFAVDLVEFDPKYEpafKYVFGDTLVVEDIEAARRLMGKYRMVTlegelfeks 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1498 ---------SRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEV 1568
Cdd:TIGR02169  653 gamtggsraPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1569 QRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLE--ELQKENKELRSEAERLGRELQQAGL 1646
Cdd:TIGR02169  733 EKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEA 812

                          650       660       670
                   ....*....|....*....|....*....|...
gi 1907176315 1647 KTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1679
Cdd:TIGR02169  813 RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 646-1545 8.94e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.42  E-value: 8.94e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  646 IGELHACIEASHQEQRQVQARVTELEAQLKaeqQKTTEREKVVQEKAQLqEQLRALEESLKITKGSLEEEKRRAADALKE 725
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIID---EKRQQLERLRREREKA-ERYQALLKEKREYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  726 Q-QCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREV 804
Cdd:TIGR02169  241 AiERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  805 ESRQKRFEARQQEearygamFQEQLMALKGEKTGQEVQEEAVeihsegqpgqqQSQLAQLHASLAKAIQQVQEKEVRAQK 884
Cdd:TIGR02169  321 EERLAKLEAEIDK-------LLAEIEELEREIEEERKRRDKL-----------TEEYAELKEELEDLRAELEEVDKEFAE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  885 LVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLkEPPRAANRASDQLGEQQgrpfssthAAVKAMEREAEQM 964
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA-DLNAAIAGIEAKINELE--------EEKEDKALEIKKQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  965 GGELERLRAALIKsqgqqqeergqQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRvEFAALQEALAHALT 1044
Cdd:TIGR02169  454 EWKLEQLAADLSK-----------YEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVR-GGRAVEEVLKASIQ 521

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1045 EKEGTDQELAKLRGQ-----EAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGAS------GEDASGPGTQSETAGKTDa 1113
Cdd:TIGR02169  522 GVHGTVAQLGSVGERyataiEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATflplnkMRDERRDLSILSEDGVIG- 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1114 pgpelqaLRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKA-LETLQGQLEEKARELGHNQAASASAQRELQALR 1192
Cdd:TIGR02169  601 -------FAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEP 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1193 AKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVET 1272
Cdd:TIGR02169  674 AELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEI 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1273 ASNSA---RAAERSSALREEVQSLREEVEKqrVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTST 1349
Cdd:TIGR02169  754 ENVKSelkELEARIEELEEDLHKLEEALND--LEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1350 QALVSELLpakhlcqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGS-----------LRQKIVEQERA 1418
Cdd:TIGR02169  832 EKEIQELQ-------EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESrlgdlkkerdeLEAQLRELERK 904

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1419 AQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqarekyvqelaavrtdaETHLAEMRQEAQSTS 1498
Cdd:TIGR02169  905 IEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS-----------------LEDVQAELQRVEEEI 967

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 1907176315 1499 RELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQ 1545
Cdd:TIGR02169  968 RALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1043-1688 1.18e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.03  E-value: 1.18e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1043 LTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDasgpgtqsETAGKTDAPGPELQALR 1122
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKD--------LGEEEQLRVKEKIGELE 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1123 AEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAE 1202
Cdd:TIGR02169  301 AEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1203 EEWKAQVargqqeaerkssliSSLEEEVSILNRqvlekegESKELKRLVVAESEKSQKLEERLRLLQVETasnsARAAER 1282
Cdd:TIGR02169  381 AETRDEL--------------KDYREKLEKLKR-------EINELKRELDRLQEELQRLSEELADLNAAI----AGIEAK 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1283 SSALREEVQSLREEVEKQRvvsensrqelasqaERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKhl 1362
Cdd:TIGR02169  436 INELEEEKEDKALEIKKQE--------------WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA-- 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1363 cqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQR------ELGELGSLRQKIVEQERAAQQ----LRAEKASYAEQ 1432
Cdd:TIGR02169  500 --RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGEryataiEVAAGNRLNNVVVEDDAVAKEaielLKRRKAGRATF 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1433 LSMLKKAHGLLaeENRGLGERANLGRQFLEVELDQAREK----------YVQELAAVR---------------------- 1480
Cdd:TIGR02169  578 LPLNKMRDERR--DLSILSEDGVIGFAVDLVEFDPKYEPafkyvfgdtlVVEDIEAARrlmgkyrmvtlegelfeksgam 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1481 -------TDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKL---TAQVEELSKKLTEHDQASKVQ 1550
Cdd:TIGR02169  656 tggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELsdaSRKIGEIEKEIEQLEQEEEKL 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1551 QQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDakkqqNQKLQEQLQDLEELQKENKEL 1630
Cdd:TIGR02169  736 KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS-----HSRIPEIQAELSKLEEEVSRI 810

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315 1631 RSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDA 1688
Cdd:TIGR02169  811 EARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEE 868
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 335-1324 1.51e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.65  E-value: 1.51e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  335 LQGAFNDLIEEHSKASQEWAEKQA---RLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPApekgevlgDAL 411
Cdd:TIGR02169  140 LQGDVTDFISMSPVERRKIIDEIAgvaEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERE--------KAE 211

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  412 QLDTLKQEaaKLATDNTQLQTRVETLEcergKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 491
Cdd:TIGR02169  212 RYQALLKE--KREYEGYELLKEKEALE----RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG 285

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  492 AQLTAQLTSmtglnatlqqrdqELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSslklKEQQLEEAAKEQEAT 571
Cdd:TIGR02169  286 EEEQLRVKE-------------KIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK----LLAEIEELEREIEEE 348

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  572 RQDHAQQLAIVAEAREaslrERDTARQQLETVEKEKDA---KLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGE 648
Cdd:TIGR02169  349 RKRRDKLTEEYAELKE----ELEDLRAELEEVDKEFAEtrdELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD 424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  649 LHACIEASHQEQRQVQARVTELEAQLKaeqQKTTEREKVVQEKAQLQEQLRALEESLKItkgsLEEEKRRAADALKEQQC 728
Cdd:TIGR02169  425 LNAAIAGIEAKINELEEEKEDKALEIK---KQEWKLEQLAADLSKYEQELYDLKEEYDR----VEKELSKLQRELAEAEA 497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  729 RATEMEAESRSlmeqREREQKELEQEKAGRKGLEARIQQLEEAHQAETE-ALRHELAEATASQHRAESECERLIREVESR 807
Cdd:TIGR02169  498 QARASEERVRG----GRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRRKAG 573

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  808 QKRFEARQQeearygaMFQEQLMALKGEKTGqeVQEEAVEihsegqpgqqqsqLAQLHASLAKAIQQVqekeVRAQKLVD 887
Cdd:TIGR02169  574 RATFLPLNK-------MRDERRDLSILSEDG--VIGFAVD-------------LVEFDPKYEPAFKYV----FGDTLVVE 627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  888 DLSALQEKM-----------------AATNKEVACLKTLVLKAGEQQETASL-ELLKEPPRAANRASDQLGEQQGRPFSS 949
Cdd:TIGR02169  628 DIEAARRLMgkyrmvtlegelfeksgAMTGGSRAPRGGILFSRSEPAELQRLrERLEGLKRELSSLQSELRRIENRLDEL 707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  950 THAAvkameREAEQMGGELERlraaliksqgqqqeergqqerevarltqERGQAQADLAQEKAAKAELEMRLQntlneqr 1029
Cdd:TIGR02169  708 SQEL-----SDASRKIGEIEK----------------------------EIEQLEQEEEKLKERLEELEEDLS------- 747

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1030 vefaALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpaggasgedasgpgTQSETAG 1109
Cdd:TIGR02169  748 ----SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS---------------KLEEEVS 808

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1110 KTDApgpELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQ 1189
Cdd:TIGR02169  809 RIEA---RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG 885

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1190 ALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAE------SEKSQKLEE 1263
Cdd:TIGR02169  886 DLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsledvQAELQRVEE 965

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176315 1264 RLRLLQvetaSNSARAAERSsalrEEVQSLREEVEKQRVVSENSRQELASQAERAEELGQE 1324
Cdd:TIGR02169  966 EIRALE----PVNMLAIQEY----EEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
243-750 3.78e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 75.08  E-value: 3.78e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  243 TEKDAQIAMMQQRIDHlALLNEKQAASSQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS 312
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  313 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQ 382
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  383 GKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQL 462
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  463 ASLIADLQSSVSNLSQAKEELEQA--------------------SQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQA 522
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAGkcpecgqpvegsphvetieeDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  523 K-----KEQAQMLQ--------TMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaiVAEAREAS 589
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEARE--------EVAELNSK 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  590 LRERDTARQQLETVEkEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACI-EASHQEQRQVQARVT 668
Cdd:PRK02224   581 LAELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFdEARIEEAREDKERAE 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  669 ELEAQLKAE-QQKTTEREKVVQEKAQLQEQLRALEEsLKITKGSLeEEKRRAADALKEQQCRATEMEAESRSLMEQRERE 747
Cdd:PRK02224   660 EYLEQVEEKlDELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLRAELRQRNVE 737


                   ...
gi 1907176315  748 QKE 750
Cdd:PRK02224   738 TLE 740
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
537-1230 3.83e-13

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 75.34  E-value: 3.83e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  537 EQAAQGLRQQVEQLSSSlklkEQQLEEAAKeqeatRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDA-KLESLQ 615
Cdd:COG4913    224 FEAADALVEHFDDLERA----HEALEDARE-----QIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQrRLELLE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  616 QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQ 695
Cdd:COG4913    295 AELEELRAELARLEAELERLEARLDALREELDELEA------QIRGNGGDRLEQLEREIERLER---ELEERERRRARLE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  696 EQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEeahqAE 775
Cdd:COG4913    366 ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIP----AR 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  776 TEALRHELAEATASqhrAESE----CErLIrEVESRQKRFEA------RQQE-----EARYGAMFQEqlmALKGEKTGQE 840
Cdd:COG4913    442 LLALRDALAEALGL---DEAElpfvGE-LI-EVRPEEERWRGaiervlGGFAltllvPPEHYAAALR---WVNRLHLRGR 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  841 VQEEAVEIHSEGQPGQQ---QSQLAQLHASLAKAIQQVQEKEVRAQKL--VDDLSAL-QEKMAATnkeVACLKTLVLKAG 914
Cdd:COG4913    514 LVYERVRTGLPDPERPRldpDSLAGKLDFKPHPFRAWLEAELGRRFDYvcVDSPEELrRHPRAIT---RAGQVKGNGTRH 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  915 EQQetaslellkepPRAANRASDQLGeqqgrpfSSTHAAVKAMEREAEQMGGELERLRAALikSQGQQQEERGQQEREVA 994
Cdd:COG4913    591 EKD-----------DRRRIRSRYVLG-------FDNRAKLAALEAELAELEEELAEAEERL--EALEAELDALQERREAL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  995 RLTQERGQAQADLAQEKAAKAELEMRLQNtLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTL 1074
Cdd:COG4913    651 QRLAEYSWDEIDVASAEREIAELEAELER-LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEEL 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1075 EQLKIQLvkkekehpaggasgedasgpgtQSETAGKTDAPGPELQALRAEisklEQQCQQQQQQVEGLTHSLKSERACRA 1154
Cdd:COG4913    730 DELQDRL----------------------EAAEDLARLELRALLEERFAA----ALGDAVERELRENLEERIDALRARLN 783

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315 1155 EQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHS--KAEEEWKAQVARgqQEAERKSSLISSLEEEV 1230
Cdd:COG4913    784 RAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGlpEYEERFKELLNE--NSIEFVADLLSKLRRAI 859
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 774-1638 1.32e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.56  E-value: 1.32e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  774 AETEALRHELAEATASQHRAESecerLIREVESRQKRFEARQQEEARYgamfqeqlMALKGEKTGQEVQEEAVEIHS-EG 852
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDL----IIDEKRQQLERLRREREKAERY--------QALLKEKREYEGYELLKEKEAlER 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  853 QPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEK-MAATNKEVACLKTLVLKAgeqqeTASLELLKEPPRA 931
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVKEKIGEL-----EAEIASLERSIAE 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  932 ANRASDQLGEQQGRPFSSTHAavkaMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEK 1011
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDK----LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1012 AAKAELEMrLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQ-------QTLEQLKIQLVKK 1084
Cdd:TIGR02169  389 DYREKLEK-LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAleikkqeWKLEQLAADLSKY 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1085 EKEHpaggasgedasgpgtqSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGlthslksERACRAEQDKALETLQ 1164
Cdd:TIGR02169  468 EQEL----------------YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRG-------GRAVEEVLKASIQGVH 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1165 GQLEEKAR-ELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQ------QEAERKSSLISSLEEEVSI---LN 1234
Cdd:TIGR02169  525 GTVAQLGSvGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRatflplNKMRDERRDLSILSEDGVIgfaVD 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1235 RQVLEKEGESKEL----KRLVVAESEKSQKLEERLRLLQVET-----------ASNSARAAE-RSSALREEVQSLREEVE 1298
Cdd:TIGR02169  605 LVEFDPKYEPAFKyvfgDTLVVEDIEAARRLMGKYRMVTLEGelfeksgamtgGSRAPRGGIlFSRSEPAELQRLRERLE 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1299 KQRVVSENSRQELASQAERAEELGQELKAWQEKffqkeqaLSALQLEhtstqalvsellpakhlcqqlqaeqaaaekrfR 1378
Cdd:TIGR02169  685 GLKRELSSLQSELRRIENRLDELSQELSDASRK-------IGEIEKE--------------------------------I 725

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1379 EELEQSKQAAGGLQAELMRaqrelgELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhgllaeenrglgeRANLGR 1458
Cdd:TIGR02169  726 EQLEQEEEKLKERLEELEE------DLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA-------------LNDLEA 786

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1459 QFLEVELDQAREKYvQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQK---LTAQVEE 1535
Cdd:TIGR02169  787 RLSHSRIPEIQAEL-SKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEienLNGKKEE 865

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1536 LSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAK---THYDAKKQQNQK 1612
Cdd:TIGR02169  866 LEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEeelSEIEDPKGEDEE 945

                          890       900
                   ....*....|....*....|....*.
gi 1907176315 1613 LQEQLQDLEELQKENKELRSEAERLG 1638
Cdd:TIGR02169  946 IPEEELSLEDVQAELQRVEEEIRALE 971
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1235-1689 1.60e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 73.41  E-value: 1.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1235 RQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQ-VETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELAS 1313
Cdd:COG4913    241 HEALEDAREQIELLEPIRELAERYAAARERLAELEyLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDA 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1314 QAERAEEL--------GQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqqlQAEQAAAEKRFREELEQSK 1385
Cdd:COG4913    321 LREELDELeaqirgngGDRLEQLEREIERLERELEERERRRARLEALLAAL----------GLPLPASAEEFAALRAEAA 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1386 QAAGGLQAELMRAQRELGELgslRQKIVEQERAAQQLRAEKAS-----------YAEQLSMLKKAHGLLAEENRGLGEra 1454
Cdd:COG4913    391 ALLEALEEELEALEEALAEA---EAALRDLRRELRELEAEIASlerrksniparLLALRDALAEALGLDEAELPFVGE-- 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1455 nlgrqFLEVELDQAR--------------------EKYVQELAAV-RTDAETHL------------AEMRQEAQSTSREL 1501
Cdd:COG4913    466 -----LIEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVnRLHLRGRLvyervrtglpdpERPRLDPDSLAGKL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1502 EVMTAKYEGAKVKVLEER---------QRFQEERQKLTA--QVEElSKKLTEHDQASKVQQQ---------KLKAFQAQR 1561
Cdd:COG4913    541 DFKPHPFRAWLEAELGRRfdyvcvdspEELRRHPRAITRagQVKG-NGTRHEKDDRRRIRSRyvlgfdnraKLAALEAEL 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1562 GESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQ--KLQEQLQDLEELQKENKELRSEAERLGR 1639
Cdd:COG4913    620 AELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREiaELEAELERLDASSDDLAALEEQLEELEA 699

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1640 ELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDAL 1689
Cdd:COG4913    700 ELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 872-1677 1.63e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 1.63e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  872 IQQVQEKEVRAQKLVDDLSALQEKMAaTNKEVAcLKTLVLKAgEQQETASLELLKEppRAANRASDQLGEQQgrpFSSTH 951
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLR-REREKA-ERYQALLK-EKREYEGYELLKE--KEALERQKEAIERQ---LASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  952 AAVKAMEREAEQMGGELERLRAALiksQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVE 1031
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLL---EELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1032 FAALQEALAhaltEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASgedasgpgtQSETAGKT 1111
Cdd:TIGR02169  328 EAEIDKLLA----EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE---------LKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1112 DAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQAL 1191
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDL 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1192 RAKAQDHSKAEEEWKAQVARG---QQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSqkLEERLRLL 1268
Cdd:TIGR02169  475 KEEYDRVEKELSKLQRELAEAeaqARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVA--AGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1269 QVETASNSARAAE---RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQL- 1344
Cdd:TIGR02169  553 VVEDDAVAKEAIEllkRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAa 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1345 -EHTSTQALVS---ELLPAKHLCQQLQAEQAAAEKRFREELEQSKQaaggLQAELMRAQRELGelgSLRQKIVEQERAAQ 1420
Cdd:TIGR02169  633 rRLMGKYRMVTlegELFEKSGAMTGGSRAPRGGILFSRSEPAELQR----LRERLEGLKRELS---SLQSELRRIENRLD 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1421 QLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDaethLAEMRQEAQSTSRE 1500
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS-SLEQEIENVKSELKELEAR----IEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1501 LEVMTAKYEGAKVKVLEERQRFQEE-RQKLTAQVEELskkltehdqaskvqQQKLKAFQAQRGESQQEVQRLQTQLNELQ 1579
Cdd:TIGR02169  781 LNDLEARLSHSRIPEIQAELSKLEEeVSRIEARLREI--------------EQKLNRLTLEKEYLEKEIQELQEQRIDLK 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1580 AQLSQKEQAAEHYKLQMEKakthydaKKQQNQKLQEQLQDLEE----LQKENKELRSEAERLGRELQQAGLKTKEAEQTC 1655
Cdd:TIGR02169  847 EQIKSIEKEIENLNGKKEE-------LEEELEELEAALRDLESrlgdLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          810       820
                   ....*....|....*....|..
gi 1907176315 1656 RHLTAQVRSLEAQVAHADQQLR 1677
Cdd:TIGR02169  920 SELKAKLEALEEELSEIEDPKG 941
HkD_SF cd22211
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ...
 8-136 2.35e-12

Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.


Pssm-ID: 411792  Cd Length: 145  Bit Score: 66.53  E-value: 2.35e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315    8 AATLLSWVNSLHVADPVETVLQLQDCSIFIKIINTI---HDTKEGQQILQQPLP-----ERLDFVCSFLQKNRKH----P 75
Cdd:cd22211      1 EAALLAWINTFPLSSPVESLDDLSDGVVLAEILSQIdpsYFDSEWLESRDSSDNwvlklNNLKKLYRSLSKYYREvlgqQ 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315   76 SSTQCLVSVQKV-IEGSEMELAKMIMLFLYQSTMSSRNLRD---WEQFEYGVQAELAVILKFMLD 136
Cdd:cd22211     81 LSDLPLPDLSAIaRDGDEEEIVKLLELVLGAAVQCENKEEYiarIQQLDESTQAELMLIIQEVLE 145
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 512-1339 4.40e-12

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 71.93  E-value: 4.40e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  512 DQELASLKEQAKKEQAQmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQlAIVAEAREASLR 591
Cdd:pfam02463  159 EEEAAGSRLKRKKKEAL-KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE-YLLYLDYLKLNE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  592 ERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhacIEASHQEQRQVQARVTELE 671
Cdd:pfam02463  237 ERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKE---EEELKSELLKLERRKVDDE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  672 AQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKEL 751
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  752 EQEKAGRKGLEARIQqlEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMA 831
Cdd:pfam02463  394 EEELELKSEEEKEAQ--LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  832 LKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEK-----------------EVRAQKLVDDLSALQE 894
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDgvggriisahgrlgdlgVAVENYKVAISTAVIV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  895 KMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPF--SSTHAAVKAMEREAEQMGGELERLR 972
Cdd:pfam02463  552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNlaQLDKATLEADEDDKRAKVVEGILKD 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  973 AALIKSQGQQQEERGQQEREVARL-----TQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKE 1047
Cdd:pfam02463  632 TELTKLKESAKAKESGLRKGVSLEeglaeKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1048 GTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpagGASGEDASGPGTQSETAGKTDAPGPELQALRAEISK 1127
Cdd:pfam02463  712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEE----EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1128 LEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKA 1207
Cdd:pfam02463  788 VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEE 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1208 QVARG------QQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAE 1281
Cdd:pfam02463  868 LLQELllkeeeLEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADE 947

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176315 1282 RSSA------LREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQAL 1339
Cdd:pfam02463  948 KEKEennkeeEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAI 1011
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1176-1708 8.46e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 70.71  E-value: 8.46e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1176 HNQAASASAQRE-LQALRAKAQDHSKAEEEwkaqvaRGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAE 1254
Cdd:COG4913    241 HEALEDAREQIElLEPIRELAERYAAARER------LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1255 SEKSQKLEERLRLLQVETASNSARAAERssaLREEVQSLREEVEKQRVVSEN--------------SRQELASQ----AE 1316
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDRLEQ---LEREIERLERELEERERRRARleallaalglplpaSAEEFAALraeaAA 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1317 RAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL------LPAKHLcqqlqaeqaaaekRFREELEqskQAAGG 1390
Cdd:COG4913    392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLerrksnIPARLL-------------ALRDALA---EALGL 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1391 LQAEL--------MRAQREL------GELGSLRQKI-VEQERAAQQLRaekasYAEQLSMLKKAHGLLAEENRGLGERAN 1455
Cdd:COG4913    456 DEAELpfvgelieVRPEEERwrgaieRVLGGFALTLlVPPEHYAAALR-----WVNRLHLRGRLVYERVRTGLPDPERPR 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1456 LGRQFL----EVELDQAREkYVQELAAVRTDAE--THLAEMRQEAQ--------STSRELEVMTAKYEGAKVKVL----- 1516
Cdd:COG4913    531 LDPDSLagklDFKPHPFRA-WLEAELGRRFDYVcvDSPEELRRHPRaitragqvKGNGTRHEKDDRRRIRSRYVLgfdnr 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1517 EERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQ--AQRGESQQEVQRLQTQLNELQAQ----------LSQ 1584
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELEAElerldassddLAA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1585 KEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVR- 1663
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRe 769

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1907176315 1664 SLEAQVAHADQQLRDL-GKFQVATDALKSREPQVKPQLDLSIDSLD 1708
Cdd:COG4913    770 NLEERIDALRARLNRAeEELERAMRAFNREWPAETADLDADLESLP 815
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 450-648 8.99e-12

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 71.02  E-value: 8.99e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  450 AERSRFEDEKQQLASLIADLQSSVSNLSQAKeeLEQASQAQGAQL-------TAQLTSMT-GLNAtLQQRDQELASLKEQ 521
Cdd:NF012221  1569 ADRQRLEQEKQQQLAAISGSQSQLESTDQNA--LETNGQAQRDAIleesravTKELTTLAqGLDA-LDSQATYAGESGDQ 1645

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  522 AKKEQAQ-MLQTMQEQ-EQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQ-----QLAIVAEAREASLRERD 594
Cdd:NF012221  1646 WRNPFAGgLLDRVQEQlDDAKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQnqanaEQDIDDAKADAEKRKDD 1725

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907176315  595 TARQQLETVEKEKDAKLESLQQQLQAANDARdNAQTSVTQAQQEKAELSQKIGE 648
Cdd:NF012221  1726 ALAKQNEAQQAESDANAAANDAQSRGEQDAS-AAENKANQAQADAKGAKQDESD 1778
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 381-960 9.08e-12

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 70.64  E-value: 9.08e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  381 LQGKLSQLEDQATRLQESpapeKGEVLGDALQLDTLKQEAA--------KLATDNTQLQTRVETLECERGKQEAQLLAER 452
Cdd:pfam12128  246 LQQEFNTLESAELRLSHL----HFGYKSDETLIASRQEERQetsaelnqLLRTLDDQWKEKRDELNGELSAADAAVAKDR 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  453 SRFED-EKQQLASLIADLQSSVSNLSQA---KEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQ 528
Cdd:pfam12128  322 SELEAlEDQHGAFLDADIETAAADQEQLpswQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAK 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  529 MLQTMQEQEQAAQG--------LRQQVEQLSSSLKLKEQQLEEAAKEqEATRQDHAQQLAIVAEAREASLRERDTARQQL 600
Cdd:pfam12128  402 IREARDRQLAVAEDdlqaleseLREQLEAGKLEFNEEEYRLKSRLGE-LKLRLNQATATPELLLQLENFDERIERAREEQ 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  601 EtvekEKDAKLESLQQQLQAANDARDNA-------QTSVTQAQQEKAELSQ----KIGELHACIEASHQEQRQVQARVTE 669
Cdd:pfam12128  481 E----AANAEVERLQSELRQARKRRDQAsealrqaSRRLEERQSALDELELqlfpQAGTLLHFLRKEAPDWEQSIGKVIS 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  670 LEAQLKAEQQKTTEREKVVQEKAQLQEQLRaLEESLKITKGSLEEEKRRAADALKE----QQCRATEMEAESRSLMEQRE 745
Cdd:pfam12128  557 PELLHRTDLDPEVWDGSVGGELNLYGVKLD-LKRIDVPEWAASEEELRERLDKAEEalqsAREKQAAAEEQLVQANGELE 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  746 REQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAM- 824
Cdd:pfam12128  636 KASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTe 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  825 FQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVA 904
Cdd:pfam12128  716 KQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVL 795

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315  905 CLKTLvlkageQQETASLE--LLKEPPRAANRASDQLGEQQGRPFSSTHAAVKAMERE 960
Cdd:pfam12128  796 RYFDW------YQETWLQRrpRLATQLSNIERAISELQQQLARLIADTKLRRAKLEME 847
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 213-814 1.36e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.10  E-value: 1.36e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  213 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLAllnekqaassqepSELEELRGKNESLTVRLHE 292
Cdd:TIGR02169  288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLL-------------AEIEELEREIEEERKRRDK 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  293 TLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSK---ASQEWAEKQARLENELSTALQ 369
Cdd:TIGR02169  355 LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRlqeELQRLSEELADLNAAIAGIEA 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  370 DKKCLEEKNEILQGKLSQLEDQATRLQEspapekgevlgdalQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLL 449
Cdd:TIGR02169  435 KINELEEEKEDKALEIKKQEWKLEQLAA--------------DLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  450 AERSRFEDEKQQLASLIADLQS---SVSNLSQAKEELEQASQ-AQGAQLTA--------------QLTSMTGLNAT---- 507
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQGvhgTVAQLGSVGERYATAIEvAAGNRLNNvvveddavakeaieLLKRRKAGRATflpl 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  508 --LQQRDQELASLKEQAKKEQAQMLQTMQEQEQAA--------------------------------------------- 540
Cdd:TIGR02169  581 nkMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAfkyvfgdtlvvedieaarrlmgkyrmvtlegelfeksgamtggsr 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  541 ---------QGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKL 611
Cdd:TIGR02169  661 aprggilfsRSEPAELQRLRERLEGLKRELSSLQSELRRIEN-RLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERL 739

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  612 ESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEA-----SHQEQRQVQ--------------ARVTELEA 672
Cdd:TIGR02169  740 EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlSHSRIPEIQaelskleeevsrieARLREIEQ 819

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  673 QLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELE 752
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR 899

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315  753 QEKAGRKGLEARIQQLEEaHQAETEALRHELAEATASQHRA------ESECERLIREVESRQKRFEAR 814
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRK-RLSELKAKLEALEEELSEIEDPkgedeeIPEEELSLEDVQAELQRVEEE 966
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
324-803 1.82e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 69.94  E-value: 1.82e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  324 KVREFANHLQQLQGAFNDLIEEHSKASQ-----------EWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQA 392
Cdd:COG4913    246 DAREQIELLEPIRELAERYAAARERLAEleylraalrlwFAQRRLELLEAELEELRAELARLEAELERLEARLDALREEL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  393 TRLQESPAPEKGEVLGD-ALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQS 471
Cdd:COG4913    326 DELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEE 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  472 SVSNLSQAKEELEQASQaqgaQLTAQLTSMTGLNATLQQRDQEL-ASLKEQAKKEQAQM-----LQTMQEQEQAAQG--- 542
Cdd:COG4913    406 ALAEAEAALRDLRRELR----ELEAEIASLERRKSNIPARLLALrDALAEALGLDEAELpfvgeLIEVRPEEERWRGaie 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  543 --LRQQ-----------------VEQLSSSLKLKEQQLEEAAKEQEATRQDH---AQQLAI----VAEAREASLRER--- 593
Cdd:COG4913    482 rvLGGFaltllvppehyaaalrwVNRLHLRGRLVYERVRTGLPDPERPRLDPdslAGKLDFkphpFRAWLEAELGRRfdy 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  594 ---DTArQQLETVEK---------------EKD----------------AKLESLQQQLQAANDARDNAQTSVTQAQQEK 639
Cdd:COG4913    562 vcvDSP-EELRRHPRaitragqvkgngtrhEKDdrrrirsryvlgfdnrAKLAALEAELAELEEELAEAEERLEALEAEL 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  640 AELSQKIGELHACIEASHQEQ--RQVQARVTELEAQLKAE-------QQKTTEREKVVQEKAQLQEQLRALEEslkiTKG 710
Cdd:COG4913    641 DALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLdassddlAALEEQLEELEAELEELEEELDELKG----EIG 716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  711 SLEEEKRRAADALKEQQCRATEMEAESRSLMEQRereqkeleqekagrkgLEARIQQL--EEAHQAETEALRHELAEATA 788
Cdd:COG4913    717 RLEKELEQAEEELDELQDRLEAAEDLARLELRAL----------------LEERFAAAlgDAVERELRENLEERIDALRA 780

                          570
                   ....*....|....*
gi 1907176315  789 SQHRAESECERLIRE 803
Cdd:COG4913    781 RLNRAEEELERAMRA 795
PTZ00121 PTZ00121
MAEBL; Provisional
 1144-1653 5.83e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.24  E-value: 5.83e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1144 HSLKSERACRAEQDKALETLQGQLEEKARElgHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLI 1223
Cdd:PTZ00121  1056 HEGKAEAKAHVGQDEGLKPSYKDFDFDAKE--DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA 1133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1224 SSLEEEVSIlnrqvlEKEGESKELKRLVVA-ESEKSQKLEERLRLLQVETASNSARAAERSSAlrEEVQSLRE--EVEKQ 1300
Cdd:PTZ00121  1134 RKAEDARKA------EEARKAEDAKRVEIArKAEDARKAEEARKAEDAKKAEAARKAEEVRKA--EELRKAEDarKAEAA 1205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1301 RVVSENSRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcQQLQAEQAAAEKRFREE 1380
Cdd:PTZ00121  1206 RKAEEERKAEEARKAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF--ARRQAAIKAEEARKADE 1282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1381 LEQSKQAAgglQAELMRAQRELGELGSLRQKiVEQERAAQQLRAEKASYAEQLSMLKKAhgllAEENRGLGERAnlgrqf 1460
Cdd:PTZ00121  1283 LKKAEEKK---KADEAKKAEEKKKADEAKKK-AEEAKKADEAKKKAEEAKKKADAAKKK----AEEAKKAAEAA------ 1348

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1461 leveldqarekyvqelaavrtdaethlaemRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKL--TAQVEELSK 1538
Cdd:PTZ00121  1349 ------------------------------KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAeeKKKADEAKK 1398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1539 KLTEHDQasKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQ 1618
Cdd:PTZ00121  1399 KAEEDKK--KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK 1476

                          490       500       510
                   ....*....|....*....|....*....|....*...
gi 1907176315 1619 DLEELQKENKELRSEAERLGR---ELQQAGLKTKEAEQ 1653
Cdd:PTZ00121  1477 KKAEEAKKADEAKKKAEEAKKkadEAKKAAEAKKKADE 1514
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 292-771 8.59e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.35  E-value: 8.59e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  292 ETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENeLSTALQDK 371
Cdd:TIGR04523  135 ENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSN-LKKKIQKN 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  372 KCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKlatDNTQLQTRVETLE------CERGKQE 445
Cdd:TIGR04523  214 KSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNK---IKKQLSEKQKELEqnnkkiKELEKQL 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  446 AQLLAERSRFEDEKQQ--LASLIADLQSSVSNLSQAKEELEQASQA------QGAQLTAQLTSMTGLNATLQQRDQELAS 517
Cdd:TIGR04523  291 NQLKSEISDLNNQKEQdwNKELKSELKNQEKKLEEIQNQISQNNKIisqlneQISQLKKELTNSESENSEKQRELEEKQN 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  518 LKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEARE--ASLRERDT 595
Cdd:TIGR04523  371 EIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSeiKDLTNQDS 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  596 ArqqLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQE--------------KAELSQKIGELHACIEASHQEQR 661
Cdd:TIGR04523  451 V---KELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKElkskekelkklneeKKELEEKVKDLTKKISSLKEKIE 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  662 QVQARVTELE---AQLKAEQQKTTEREKVVQEKAQLQEQLRALEEsLKITKGSLEEEKRRAADALKEQQCRATEMEAESR 738
Cdd:TIGR04523  528 KLESEKKEKEskiSDLEDELNKDDFELKKENLEKEIDEKNKEIEE-LKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIE 606

                          490       500       510
                   ....*....|....*....|....*....|...
gi 1907176315  739 SLMEQREREQKELEQEKAGRKGLEARIQQLEEA 771
Cdd:TIGR04523  607 EKEKKISSLEKELEKAKKENEKLSSIIKNIKSK 639
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
216-851 2.77e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.86  E-value: 2.77e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  216 RLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLAL----LNEKQAASSQEPSELEELRGKNESLTVRLH 291
Cdd:PRK03918   169 EVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSelpeLREELEKLEKEVKELEELKEEIEELEKELE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  292 ETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFaNHLQQLQGAFNDLIEEHSkasqEWAEKQARLENELSTALQDK 371
Cdd:PRK03918   249 SLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYIKLSEFYE----EYLDELREIEKRLSRLEEEI 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  372 KCLEEKNEILQGKLSQLEDQATRLQESpAPEKGEVLGDALQLDTLKQEAAKLatdnTQLQTRVETLECERGKQEAQLLAE 451
Cdd:PRK03918   324 NGIEERIKELEEKEERLEELKKKLKEL-EKRLEELEERHELYEEAKAKKEEL----ERLKKRLTGLTPEKLEKELEELEK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  452 R-SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQ---AQGAQLTAQ-----LTSMTGLNATLQQRDQELASLKEQA 522
Cdd:PRK03918   399 AkEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpVCGRELTEEhrkelLEEYTAELKRIEKELKEIEEKERKL 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  523 KKEQAQmLQTMQEQEQAAQGLRQQVEQLSS-SLKLKEQQLEEAAKEqeatrqdhaqqlaivAEAREASLRERDTARQQLE 601
Cdd:PRK03918   479 RKELRE-LEKVLKKESELIKLKELAEQLKElEEKLKKYNLEELEKK---------------AEEYEKLKEKLIKLKGEIK 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  602 TVEKEKDaKLESLQQQLQAANDARDNaqtsvtqAQQEKAELSQKIGEL-HACIEashqeqrQVQARVTELEAQLKaeqqK 680
Cdd:PRK03918   543 SLKKELE-KLEELKKKLAELEKKLDE-------LEEELAELLKELEELgFESVE-------ELEERLKELEPFYN----E 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  681 TTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQcratemEAESRSLMEQREREQKELEQEKAGRKG 760
Cdd:PRK03918   604 YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE------ELEKKYSEEEYEELREEYLELSRELAG 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  761 LEARIQQLEEaHQAETEALRHELAEATASQHRAESECERLirevESRQKRFEARQQEEARYGAMFQEQLMalkgektgQE 840
Cdd:PRK03918   678 LRAELEELEK-RREEIKKTLEKLKEELEEREKAKKELEKL----EKALERVEELREKVKKYKALLKERAL--------SK 744

                          650
                   ....*....|.
gi 1907176315  841 VQEEAVEIHSE 851
Cdd:PRK03918   745 VGEIASEIFEE 755
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 605-813 4.68e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 64.01  E-value: 4.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  605 KEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTER 684
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  685 ekvvqeKAQLQEQLRALEESLKITK--------------------GSLEEEKRRAADALKEQQCRATEMEAESRSLMEQR 744
Cdd:COG4942    103 ------KEELAELLRALYRLGRQPPlalllspedfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315  745 EREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEA 813
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
429-820 5.81e-10

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 64.40  E-value: 5.81e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  429 QLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQAsQAQGAQLTAQLTSMTGLNAtL 508
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEEL-EAELEELREELEKLEKLLQ-L 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  509 QQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREA 588
Cdd:COG4717    128 LPLYQELEALEAELAELPER-LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQ 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  589 SLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT-----------SVTQAQQEKAELSQKIGELHACIEASH 657
Cdd:COG4717    207 RLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEArlllliaaallALLGLGGSLLSLILTIAGVLFLVLGLL 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  658 QEQRQVQARVTELEAQLKAEQQKTTEREKVvqEKAQLQEQLRALEESLKITKGSLEEEKRRAADAlkeQQCRATEMEAES 737
Cdd:COG4717    287 ALLFLLLAREKASLGKEAEELQALPALEEL--EEEELEELLAALGLPPDLSPEELLELLDRIEEL---QELLREAEELEE 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  738 RSLMEQREREQKELEQEK--AGRKGLEARIQQLEEAHQAETE--ALRHELAE---------ATASQHRAESECERLIREV 804
Cdd:COG4717    362 ELQLEELEQEIAALLAEAgvEDEEELRAALEQAEEYQELKEEleELEEQLEEllgeleellEALDEEELEEELEELEEEL 441

                          410
                   ....*....|....*.
gi 1907176315  805 ESRQKRFEARQQEEAR 820
Cdd:COG4717    442 EELEEELEELREELAE 457
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
458-1077 8.24e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.17  E-value: 8.24e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  458 EKQQLASLIADLQSSVSNLSQAKEELEQASQaqgaqltaQLTSMTGLNATLQQRDQELASLKEQakkEQAQMLQTMQEQE 537
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALEDARE--------QIELLEPIRELAERYAAARERLAEL---EYLRAALRLWFAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  538 QAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQqlaIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQ 617
Cdd:COG4913    288 RRLELLEAELEELRAELARLEAELERLEARLDALREELDE---LEAQIRGNGGDRLEQLEREIERLERELEERERRRARL 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  618 LQAANDARdnaqtsvTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQqktterekvvQEKAQLQEQ 697
Cdd:COG4913    365 EALLAALG-------LPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR----------RELRELEAE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  698 LRALEESlkitKGSLEEEKRRAADALKEqQCRATEME----AEsrsLMEQREREQK------------------ELEQEK 755
Cdd:COG4913    428 IASLERR----KSNIPARLLALRDALAE-ALGLDEAElpfvGE---LIEVRPEEERwrgaiervlggfaltllvPPEHYA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  756 AGRKGLEARiqQLEEAHQAEtealrhELAEATASQHRAESECERLIREVESRQKRFEA--RQQEEARYGAMFQEQLMALK 833
Cdd:COG4913    500 AALRWVNRL--HLRGRLVYE------RVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwlEAELGRRFDYVCVDSPEELR 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  834 GE-----KTGQEVQEEAVEIHSEGQPGQQQSQLAQlhaslaKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKT 908
Cdd:COG4913    572 RHpraitRAGQVKGNGTRHEKDDRRRIRSRYVLGF------DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  909 LVLKAGEQQETASLELLKeppRAANRASDQLGEQQGRpFSSTHAAVKAMEREAEQMGGELERLRAALiksqgqqqeergq 988
Cdd:COG4913    646 RREALQRLAEYSWDEIDV---ASAEREIAELEAELER-LDASSDDLAALEEQLEELEAELEELEEEL------------- 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  989 qerevARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELK 1068
Cdd:COG4913    709 -----DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLN 783


                   ....*....
gi 1907176315 1069 ELQQTLEQL 1077
Cdd:COG4913    784 RAEEELERA 792
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 327-701 1.23e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 63.82  E-value: 1.23e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  327 EFANHLQQLQGAFNDLIEEHSKASqEW----------AEKQARLENELStALQDKkcLEEKNEILQGKLSQLEDQATRLQ 396
Cdd:COG3096    310 EMARELEELSARESDLEQDYQAAS-DHlnlvqtalrqQEKIERYQEDLE-ELTER--LEEQEEVVEEAAEQLAEAEARLE 385

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  397 ESPApekgEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLE-CERGKQEAQLLAER-----SRFEDEKQQLASLIADLQ 470
Cdd:COG3096    386 AAEE----EVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEkARALCGLPDLTPENaedylAAFRAKEQQATEEVLELE 461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  471 SSVSNLSQAKEELEQASQAqgaqltaqLTSMTGlnatlqqrdqelASLKEQAKKEQAQMLQTMQEQEQAAQglrqQVEQL 550
Cdd:COG3096    462 QKLSVADAARRQFEKAYEL--------VCKIAG------------EVERSQAWQTARELLRRYRSQQALAQ----RLQQL 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  551 ssslklkEQQLEEAakEQEATRQDHAQQLAivaEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 630
Cdd:COG3096    518 -------RAQLAEL--EQRLRQQQNAERLL---EEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQ 585

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315  631 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEA-------QLKAEQQKTTEREKVVQEKAQLQEQLRAL 701
Cdd:COG3096    586 QLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEvtaamqqLLEREREATVERDELAARKQALESQIERL 663
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 508-927 2.30e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 62.89  E-value: 2.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  508 LQQRDQELASLKEQAKKEQAQMLQ-------------TMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEA---T 571
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKElekkhqqlceeknALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESrleE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  572 RQDHAQQLAIVAEAR-------EASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQ 644
Cdd:pfam01576   87 EEERSQQLQNEKKKMqqhiqdlEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTS 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  645 KIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQ----EKAQLQEQ---LRALEESLKITKGSLEEEKR 717
Cdd:pfam01576  167 NLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRklegESTDLQEQiaeLQAQIAELRAQLAKKEEELQ 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  718 RAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEahqaETEALRHELAE---ATASQH--- 791
Cdd:pfam01576  247 AALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGE----ELEALKTELEDtldTTAAQQelr 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  792 -RAESECERLIREVESRQKRFEARQQEEARYGAM----FQEQLMALKG-----EKTGQEVQEEAVEIHSEGQPGQQQSQl 861
Cdd:pfam01576  323 sKREQEVTELKKALEEETRSHEAQLQEMRQKHTQaleeLTEQLEQAKRnkanlEKAKQALESENAELQAELRTLQQAKQ- 401

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176315  862 aQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVlkagEQQETASLELLKE 927
Cdd:pfam01576  402 -DSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLL----NEAEGKNIKLSKD 462
mukB PRK04863
chromosome partition protein MukB;
441-1356 2.65e-09

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 62.67  E-value: 2.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  441 RGKQEAQLLAERSRFEDEKQQLAS--LIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNAtLQQRDQELASL 518
Cdd:PRK04863   282 RVHLEEALELRRELYTSRRQLAAEqyRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEK-IERYQADLEEL 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  519 KEQAKkEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLK---------LKEQQLEEAAKEQEATRQDHAQQLAIVAEAREAS 589
Cdd:PRK04863   361 EERLE-EQNEVVEEADEQQEENEARAEAAEEEVDELKsqladyqqaLDVQQTRAIQYQQAVQALERAKQLCGLPDLTADN 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  590 LRERdtaRQQLETVEKEKDAKLESLQQQL---QAANDARDNAQTSVTQA--QQEKAELSQKIGELhaciEASHQEQRQVQ 664
Cdd:PRK04863   440 AEDW---LEEFQAKEQEATEELLSLEQKLsvaQAAHSQFEQAYQLVRKIagEVSRSEAWDVAREL----LRRLREQRHLA 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  665 ARVTELEAQLKaeqqkttEREKVVQEKAQLQEQLRALEESLKITKGSLEEekrrAADALKEQQCRATEMEAESRSLMEQR 744
Cdd:PRK04863   513 EQLQQLRMRLS-------ELEQRLRQQQRAERLLAEFCKRLGKNLDDEDE----LEQLQEELEARLESLSESVSEARERR 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  745 EREQKELEQEKAGRKGLEARIQQLEEAHQA---------ETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQ 815
Cdd:PRK04863   582 MALRQQLEQLQARIQRLAARAPAWLAAQDAlarlreqsgEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEI 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  816 QEEARYGAMFQEQLMALKGEKTGQEVQE--EAVEIHSEGqpgqqqsQLAQLHASLAKAIqqvqekevraqkLVDDLSALQ 893
Cdd:PRK04863   662 ERLSQPGGSEDPRLNALAERFGGVLLSEiyDDVSLEDAP-------YFSALYGPARHAI------------VVPDLSDAA 722

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  894 EKMAAtnkEVACLKTLVLKAGEQQETAS----LELLkeppraANRASDQLGEQQGRpfSSTHAAVKAMEREAEqmggelE 969
Cdd:PRK04863   723 EQLAG---LEDCPEDLYLIEGDPDSFDDsvfsVEEL------EKAVVVKIADRQWR--YSRFPEVPLFGRAAR------E 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  970 RLRAALiksqgqqqeergqqerevarltqergQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHAltekEGT 1049
Cdd:PRK04863   786 KRIEQL--------------------------RAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAFE----ADP 835

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1050 DQELAKLRGQEAAQRTELKELQQTLEQLKIQLvKKEKEHPAGgasgedasgpgtqsetagktdapgpeLQALRAEISKLE 1129
Cdd:PRK04863   836 EAELRQLNRRRVELERALADHESQEQQQRSQL-EQAKEGLSA--------------------------LNRLLPRLNLLA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1130 qqcqqqqqqVEGLTHSLkseRACRAEQDKAletlqgqlEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQV 1209
Cdd:PRK04863   889 ---------DETLADRV---EEIREQLDEA--------EEAKRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQ 948

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1210 ARGQQEAERKSSLIS--------SLEEEVSILNRqvlEKEGESKELKRLVVAESEKSQkLEERLRLLQVETASNSARAAE 1281
Cdd:PRK04863   949 QTQRDAKQQAFALTEvvqrrahfSYEDAAEMLAK---NSDLNEKLRQRLEQAEQERTR-AREQLRQAQAQLAQYNQVLAS 1024

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315 1282 ---RSSALREEVQSLREEVEKQRVVSENSRQELAsqAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1356
Cdd:PRK04863  1025 lksSYDAKRQMLQELKQELQDLGVPADSGAEERA--RARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKL 1100
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 546-1345 3.32e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 3.32e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  546 QVEQLSSSLKLKEQQLEEAAKEqeatrqdhAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQqlqaANDAR 625
Cdd:pfam02463  143 KIEIIAMMKPERRLEIEEEAAG--------SRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQ----AKKAL 210

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  626 DNAQTSvtQAQQEKAELSQKIGELHACIEASHQEQRQVQARVtELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESL 705
Cdd:pfam02463  211 EYYQLK--EKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQ-EEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEE 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  706 KITKGSLEEEKRRAADALKEQQCRATEMEAESrslmeqrEREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAE 785
Cdd:pfam02463  288 LKLLAKEEEELKSELLKLERRKVDDEEKLKES-------EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  786 ATASQHRAESECERLIREVESRQKRFEARQQEearygamfQEQLMALKGEKtGQEVQEeaveihsegqpgqqQSQLAQLH 865
Cdd:pfam02463  361 LEKLQEKLEQLEEELLAKKKLESERLSSAAKL--------KEEELELKSEE-EKEAQL--------------LLELARQL 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  866 ASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEpprAANRASDQLGEQQGR 945
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL---VKLQEQLELLLSRQK 494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  946 PFSSTHAAVKAMEREA-EQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNT 1024
Cdd:pfam02463  495 LEERSQKESKARSGLKvLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELP 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1025 LNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQ 1104
Cdd:pfam02463  575 LGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1105 SETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASA 1184
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1185 QRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEER 1264
Cdd:pfam02463  735 NEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1265 LRLLQVETASNSARAAERSSALREEVQSLrEEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQL 1344
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELK-EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE 893


                   .
gi 1907176315 1345 E 1345
Cdd:pfam02463  894 K 894
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1375-1683 3.50e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 3.50e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1375 KRFREELEQSKQAAGGLQAelMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEnrglgera 1454
Cdd:TIGR02168  213 ERYKELKAELRELELALLV--LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE-------- 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1455 nlgrqflEVELDQAREKYVQELAAVRTDAEtHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVE 1534
Cdd:TIGR02168  283 -------IEELQKELYALANEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1535 ELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDA--KKQQNQK 1612
Cdd:TIGR02168  355 SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEEllKKLEEAE 434

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176315 1613 LQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQ 1683
Cdd:TIGR02168  435 LKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFS 505
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 509-816 4.96e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 61.68  E-value: 4.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  509 QQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDH-AQQLAIVAEARE 587
Cdd:pfam17380  303 QEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEiAMEISRMRELER 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  588 ASL---RERDTARQQLETVEKEKdakLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQ 664
Cdd:pfam17380  383 LQMerqQKNERVRQELEAARKVK---ILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQ 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  665 ARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRaleeslKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQR 744
Cdd:pfam17380  460 QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRR------KILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEE 533

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176315  745 EREqkELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEatasqhrAESECERLIREVESRQKRFEARQQ 816
Cdd:pfam17380  534 RRR--EAEEERRKQQEMEERRRIQEQMRKATEERSRLEAME-------REREMMRQIVESEKARAEYEATTP 596
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 332-809 5.35e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 61.67  E-value: 5.35e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  332 LQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEK----NEILQGKLSQLEDQATRLQES--------- 398
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQarnqNSMYMRQLSDLESTVSQLRSElreakrmye 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  399 ---PAPEKGEVLGDAlQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERS---RFEDEKQQLASLIADLQSS 472
Cdd:pfam15921  342 dkiEELEKQLVLANS-ELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEqnkRLWDRDTGNSITIDHLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  473 VSNLSQAKEELEQ-----ASQAQGaQLTAQLTSMTGLNATLQQRDQELASLkEQAKKEQAQMLQTMQEQEQAAQGLRQQV 547
Cdd:pfam15921  421 LDDRNMEVQRLEAllkamKSECQG-QMERQMAAIQGKNESLEKVSSLTAQL-ESTKEMLRKVVEELTAKKMTLESSERTV 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  548 EQLSSSLKLKEQQLEEAAKE--QEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDAR 625
Cdd:pfam15921  499 SDLTASLQEKERAIEATNAEitKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLV 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  626 DNAQTSVTQAQQEKAELSQKIG-------ELHACIEASHQEQRQVQARVTELEAQ-----------LKAEQQKTTEREKV 687
Cdd:pfam15921  579 GQHGRTAGAMQVEKAQLEKEINdrrlelqEFKILKDKKDAKIRELEARVSDLELEkvklvnagserLRAVKDIKQERDQL 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  688 VQEKAQLQEQLRALEESLKITKGSLE---EEKRRAADALKEQQCRATEMEAESRSLMEQRERE-----------QKELEQ 753
Cdd:pfam15921  659 LNEVKTSRNELNSLSEDYEVLKRNFRnksEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgmQKQITA 738

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176315  754 EKAGRKGLEARIQQLEEAH----------QAETEALRHELAEATASQHRAESECErLIREVESRQK 809
Cdd:pfam15921  739 KRGQIDALQSKIQFLEEAMtnankekhflKEEKNKLSQELSTVATEKNKMAGELE-VLRSQERRLK 803
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
412-974 7.54e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.08  E-value: 7.54e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSrfEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 491
Cdd:COG4913    256 PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAEL--EELRAELARLEAELERLEARLDALREELDELEAQIR 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  492 AQLTAQLtsmtglnatlqqrdqelaslkEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 571
Cdd:COG4913    334 GNGGDRL---------------------EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  572 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEkdakLESLQQQlqaandardnaQTSVTQAQQE-KAELSQK----- 645
Cdd:COG4913    393 LEALEEELEALEEALAEAEAALRDLRRELRELEAE----IASLERR-----------KSNIPARLLAlRDALAEAlglde 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  646 -----IGELhacIEASHQEQR--------------------QVQARVTELEAQLKAEQQKTTERekvVQEKAQLQEQLRA 700
Cdd:COG4913    458 aelpfVGEL---IEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVNRLHLRGRLVYER---VRTGLPDPERPRL 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  701 LEESL--KIT------KGSLEEEKRRAADALKeqqCR-ATEMEAESRSLMEQREREQKELEQEKAGRKGLEAR------- 764
Cdd:COG4913    532 DPDSLagKLDfkphpfRAWLEAELGRRFDYVC---VDsPEELRRHPRAITRAGQVKGNGTRHEKDDRRRIRSRyvlgfdn 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  765 IQQLeeahqaetEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEarygAMFQEQLMALKGEKTGQEVQEE 844
Cdd:COG4913    609 RAKL--------AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLA----EYSWDEIDVASAEREIAELEAE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  845 AVEIHSEgqpgqqQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLEL 924
Cdd:COG4913    677 LERLDAS------SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL 750

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176315  925 LKEppRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQmggELERLRAA 974
Cdd:COG4913    751 LEE--RFAAALGDAVERELRENLEERIDALRARLNRAEE---ELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 463-681 1.28e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.39  E-value: 1.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  463 ASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQG 542
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  543 LRQQVEQLSSSLKlKEQQLEEAAKEQEATRQDHAQQLAI-------VAEAREASLRERDTARQQLETVEKEKDAKLESLQ 615
Cdd:COG4942     99 LEAQKEELAELLR-ALYRLGRQPPLALLLSPEDFLDAVRrlqylkyLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176315  616 QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKT 681
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 998-1681 1.50e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 60.35  E-value: 1.50e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  998 QERGQAQADLAQE--KAAKAELEmRLQNTLNEQRVEFAALQEAL-----AHALTEK-----EGTDQELAKLRGQEAAQRT 1065
Cdd:COG3096    377 LAEAEARLEAAEEevDSLKSQLA-DYQQALDVQQTRAIQYQQAVqalekARALCGLpdltpENAEDYLAAFRAKEQQATE 455

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1066 ELKELQQTLEQLKI---------QLVKKekehPAGGASGEDASGPGTQS-ETAGKTDAPGPELQALRAEISKLEQQCQQQ 1135
Cdd:COG3096    456 EVLELEQKLSVADAarrqfekayELVCK----IAGEVERSQAWQTARELlRRYRSQQALAQRLQQLRAQLAELEQRLRQQ 531

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1136 QQQV---EGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEW-KAQVAR 1211
Cdd:COG3096    532 QNAErllEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWlAAQDAL 611

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1212 GQQEAERKSSLISSleEEVSILNRQVLEKEGESKELKRLVVaesEKSQKLEERLRLLQVETASNSAR------------- 1278
Cdd:COG3096    612 ERLREQSGEALADS--QEVTAAMQQLLEREREATVERDELA---ARKQALESQIERLSQPGGAEDPRllalaerlggvll 686

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1279 -----------AAERS---------------SALREEVQSL-----------------------REEVEKQRVVSENSRQ 1309
Cdd:COG3096    687 seiyddvtledAPYFSalygparhaivvpdlSAVKEQLAGLedcpedlyliegdpdsfddsvfdAEELEDAVVVKLSDRQ 766

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1310 -------EL-----ASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVsellpAKHLCQQlqaeqaaaekrF 1377
Cdd:COG3096    767 wrysrfpEVplfgrAAREKRLEELRAERDELAEQYAKASFDVQKLQRLHQAFSQFV-----GGHLAVA-----------F 830

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1378 REELEQSKQAaggLQAELMRAQRELgelgslrqkiVEQERAAQQLRAEKASYAEQLSMLKKAHG---LLAEEnrGLGERa 1454
Cdd:COG3096    831 APDPEAELAA---LRQRRSELEREL----------AQHRAQEQQLRQQLDQLKEQLQLLNKLLPqanLLADE--TLADR- 894

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1455 nlgRQFLEVELDQARE--KYVQE-----------LAAVRTDAETHlAEMRQEAQSTSRELEVMTAKYEgAKVKVLEERQR 1521
Cdd:COG3096    895 ---LEELREELDAAQEaqAFIQQhgkalaqleplVAVLQSDPEQF-EQLQADYLQAKEQQRRLKQQIF-ALSEVVQRRPH 969

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1522 FQ-EERQKLTAQVEELSKKLtehdqaskvqQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQkeqaaehyklqmekAK 1600
Cdd:COG3096    970 FSyEDAVGLLGENSDLNEKL----------RARLEQAEEARREAREQLRQAQAQYSQYNQVLAS--------------LK 1025

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1601 THYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERlgRELQQAGLKTKeaeQTCRHLTAQVRSLEAQVAHADQQLRDLG 1680
Cdd:COG3096   1026 SSRDAKQQTLQELEQELEELGVQADAEAEERARIRR--DELHEELSQNR---SRRSQLEKQLTRCEAEMDSLQKRLRKAE 1100


                   .
gi 1907176315 1681 K 1681
Cdd:COG3096   1101 R 1101
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1146-1652 1.94e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 59.74  E-value: 1.94e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1146 LKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQREL--QALRAKAQDHSKAEEEWKaQVARGQQEAERKsslI 1223
Cdd:pfam05483  160 LKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELrvQAENARLEMHFKLKEDHE-KIQHLEEEYKKE---I 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1224 SSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLlqveTASNSARAAERSSALREEVQSLREEVEKQRVV 1303
Cdd:pfam05483  236 NDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKL----QDENLKELIEKKDHLTKELEDIKMSLQRSMST 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1304 SENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKhlcqqlqaeqaaaekrfREELEQ 1383
Cdd:pfam05483  312 QKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTE-----------------QQRLEK 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1384 SKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEENRGLGERAnlgrqfleV 1463
Cdd:pfam05483  375 NEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAED----EKLLDEKKQFEKIAEELKGKEQEL--------I 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1464 ELDQAREKYVQELaavrtdaETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLE---ERQRFQEERQKLTAQVEELSKKL 1540
Cdd:pfam05483  443 FLLQAREKEIHDL-------EIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIEltaHCDKLLLENKELTQEASDMTLEL 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1541 TEHDQ----ASKVQQQKLKAFQA-------QRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQ 1609
Cdd:pfam05483  516 KKHQEdiinCKKQEERMLKQIENleekemnLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENK 595

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1907176315 1610 NQKLQEQLQD----LEELQKENKELRSEAERLGRELQQAGLKTKEAE 1652
Cdd:pfam05483  596 CNNLKKQIENknknIEELHQENKALKKKGSAENKQLNAYEIKVNKLE 642
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 252-817 2.47e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.42  E-value: 2.47e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  252 MQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS----QLSEENGDLSFKVRE 327
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAarkqELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  328 FANHLQQLQGafndlieEHSKASQEWAEKQARLENELST--ALQ-DKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKG 404
Cdd:pfam01576   87 EEERSQQLQN-------EKKKMQQHIQDLEEQLDEEEAArqKLQlEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  405 EVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQllaeRSRFEDEKQQLASLIADLQSSVSNLSQAKEELE 484
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG----RQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  485 QASQAQGAQLTAQLTSM---TGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkEQQL 561
Cdd:pfam01576  236 AQLAKKEEELQAALARLeeeTAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL---EDTL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  562 EEAAKEQEAtrqdHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 641
Cdd:pfam01576  313 DTTAAQQEL----RSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  642 LSQKIGELHACIEASHQEQRQVQARVTELEAQL-KAEQQKTTEREKVVQEKAQLQEQLRALEE----SLKITK--GSLEE 714
Cdd:pfam01576  389 LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLsESERQRAELAEKLSKLQSELESVSSLLNEaegkNIKLSKdvSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  715 EKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLeeahQAETEALRHELAEATASQHRAE 794
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTL----QAQLSDMKKKLEEDAGTLEALE 544

                          570       580
                   ....*....|....*....|...
gi 1907176315  795 SECERLIREVESRQKRFEARQQE 817
Cdd:pfam01576  545 EGKKRLQRELEALTQQLEEKAAA 567
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
798-1331 2.57e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 2.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  798 ERLIREVESRQKRFEArqQEEARYGAMFQEQLMALKgektgQEVQEEAVEI-HSEGQPGQQQSQLAQLHASLAKAIQQVQ 876
Cdd:PRK02224   179 ERVLSDQRGSLDQLKA--QIEEKEEKDLHERLNGLE-----SELAELDEEIeRYEEQREQARETRDEADEVLEEHEERRE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  877 EKEVraqkLVDDLSALQEKMAATNKEVACLKTLVlkagEQQETASLELLKEppRAANRASDQLGEQQGrpfSSTHAAVKA 956
Cdd:PRK02224   252 ELET----LEAEIEDLRETIAETEREREELAEEV----RDLRERLEELEEE--RDDLLAEAGLDDADA---EAVEARREE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  957 MEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRlQNTLNEQRVEFAALQ 1036
Cdd:PRK02224   319 LEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDR-REEIEELEEEIEELR 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1037 EALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAG-----GASGEDASGPGTQSETAGKT 1111
Cdd:PRK02224   398 ERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGkcpecGQPVEGSPHVETIEEDRERV 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1112 DAPGPELQALRAEISKLEqqcqqqqqqveglthslksERACRAEQDKALETLQGQLEEKAR---ELGHNQAASASAQRE- 1187
Cdd:PRK02224   478 EELEAELEDLEEEVEEVE-------------------ERLERAEDLVEAEDRIERLEERREdleELIAERRETIEEKREr 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1188 LQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEvsilnRQVLEKEGESKELKRLVVAESEKSQKLEERLRL 1267
Cdd:PRK02224   539 AEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK-----LAELKERIESLERIRTLLAAIADAEDEIERLRE 613

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176315 1268 LQVETASNSARAAERSSALREEVQSLREEVEKQRVvsENSRQELASQAERAEELGQELKAWQEK 1331
Cdd:PRK02224   614 KREALAELNDERRERLAEKRERKRELEAEFDEARI--EEAREDKERAEEYLEQVEEKLDELREE 675
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 274-698 2.64e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 59.26  E-value: 2.64e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  274 SELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGD----LSFKVREFANHLQQLQGAFNDLIEEHSKA 349
Cdd:TIGR04523  218 SQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKikkqLSEKQKELEQNNKKIKELEKQLNQLKSEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  350 SQEWAEKQARLENELSTAL--QDKKCLEEKNEILQG--KLSQLEDQATRLQ------ESPAPEKGEVLGDAL-QLDTLKQ 418
Cdd:TIGR04523  298 SDLNNQKEQDWNKELKSELknQEKKLEEIQNQISQNnkIISQLNEQISQLKkeltnsESENSEKQRELEEKQnEIEKLKK 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  419 EAAKLATDNTQLQTRVETLECERGKQEAQ----------LLAERSRFEDEKQQLASLIADLQSSVSNLSQAK-------E 481
Cdd:TIGR04523  378 ENQSYKQEIKNLESQINDLESKIQNQEKLnqqkdeqikkLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDsvkeliiK 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  482 ELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELaslkeqakKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:TIGR04523  458 NLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL--------KSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  562 EEAAKEQEatrqdhaqqLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 641
Cdd:TIGR04523  530 ESEKKEKE---------SKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKD 600

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176315  642 LSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKtteREKVVQEKAQLQEQL 698
Cdd:TIGR04523  601 LIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSK---KNKLKQEVKQIKETI 654
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1520-1728 2.65e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 2.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1520 QRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKA 1599
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1600 KTHYDAKK----QQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQ 1675
Cdd:TIGR02168  315 ERQLEELEaqleELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ 394

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176315 1676 LRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEEGTPCSVASKLPRTQP 1728
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEE 447
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 305-675 4.39e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 4.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  305 SQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGK 384
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  385 LSQLEDQATRLQESpAPEKGEVLGDALQ-LDTLKQEAAKLATDNT-QLQTRVETLECERGKQEAQLLAErsrfEDEKQQL 462
Cdd:TIGR02169  246 LASLEEELEKLTEE-ISELEKRLEEIEQlLEELNKKIKDLGEEEQlRVKEKIGELEAEIASLERSIAEK----ERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  463 ASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAqltsmtgLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQG 542
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDK-------LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  543 LRQQVEQLsSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKekdaKLESLQQQLQAAN 622
Cdd:TIGR02169  394 LEKLKREI-NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW----KLEQLAADLSKYE 468

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176315  623 DARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLK 675
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQ 521
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1116-1647 5.65e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.15  E-value: 5.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1116 PELQALRAEISKLEQQCQQQQQQVEGLThSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKA 1195
Cdd:PRK03918   214 SELPELREELEKLEKEVKELEELKEEIE-ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1196 QDHSKAEE---EWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLV--VAESEKSQKLEERLRLLQV 1270
Cdd:PRK03918   293 EEYIKLSEfyeEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEkrLEELEERHELYEEAKAKKE 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1271 ETASNSARAAERSSalrEEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQ 1350
Cdd:PRK03918   373 ELERLKKRLTGLTP---EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEH 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1351 ALvsELLPAKHLcqqLQAEQAAAEKRFREELEQSKQAAGGLQAELMRaQRELGELGSLRQKIVEQERAAQQLRAEKASY- 1429
Cdd:PRK03918   450 RK--ELLEEYTA---ELKRIEKELKEIEEKERKLRKELRELEKVLKK-ESELIKLKELAEQLKELEEKLKKYNLEELEKk 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1430 AEQLSMLKKAHGLLAEENRGLGERANLGRQF------LEVELDQAREkyvqELAAVRTDAETHLAEMRQEAQSTSRELEV 1503
Cdd:PRK03918   524 AEEYEKLKEKLIKLKGEIKSLKKELEKLEELkkklaeLEKKLDELEE----ELAELLKELEELGFESVEELEERLKELEP 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1504 MTAKYEGAKvKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKafQAQRGESQQEVQRLQTQLNELQAQLS 1583
Cdd:PRK03918   600 FYNEYLELK-DAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE--ELEKKYSEEEYEELREEYLELSRELA 676

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176315 1584 QKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQE---QLQDLEELQKENKELRSEAERLGRELQQAGLK 1647
Cdd:PRK03918   677 GLRAELEELEKRREEIKKTLEKLKEELEEREKakkELEKLEKALERVEELREKVKKYKALLKERALS 743
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 262-864 5.98e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 58.19  E-value: 5.98e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  262 LNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNL-----------------------KTEKSQMDRKIS------ 312
Cdd:pfam05483  108 LQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLikennatrhlcnllketcarsaeKTKKYEYEREETrqvymd 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  313 -----------------QLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQ----EWAEKQARLEN--------- 362
Cdd:pfam05483  188 lnnniekmilafeelrvQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSllliQITEKENKMKDltflleesr 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  363 ------ELSTALQDKKcLEEKNEILQGKLSQLEDQATRLQESPAPEKgeVLGDALQL------------DTLKQEAAKLA 424
Cdd:pfam05483  268 dkanqlEEKTKLQDEN-LKELIEKKDHLTKELEDIKMSLQRSMSTQK--ALEEDLQIatkticqlteekEAQMEELNKAK 344

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  425 TDNTQLQTRVETLECergKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLsqakEELEQASQAQGAQLtAQLTSMTGL 504
Cdd:pfam05483  345 AAHSFVVTEFEATTC---SLEELLRTEQQRLEKNEDQLKIITMELQKKSSEL----EEMTKFKNNKEVEL-EELKKILAE 416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  505 NATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEatrQDHAQQLAIVAE 584
Cdd:pfam05483  417 DEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELE---KEKLKNIELTAH 493

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  585 AREASLRERDTARQQLETV--EKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQE----KAELSQKIGELHACIEASHQ 658
Cdd:pfam05483  494 CDKLLLENKELTQEASDMTleLKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDElesvREEFIQKGDEVKCKLDKSEE 573

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  659 EQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKitKGSLEEEKRRAADALKEQQCRaTEMEAESR 738
Cdd:pfam05483  574 NARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALK--KKGSAENKQLNAYEIKVNKLE-LELASAKQ 650

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  739 SLMEQREREQKELEQEKAGRKGLearIQQLEEAHQAETEALR----------HELAEATASQHRAESECERLIREVESRQ 808
Cdd:pfam05483  651 KFEEIIDNYQKEIEDKKISEEKL---LEEVEKAKAIADEAVKlqkeidkrcqHKIAEMVALMEKHKHQYDKIIEERDSEL 727

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176315  809 KRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQL 864
Cdd:pfam05483  728 GLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAIL 783
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1243-1670 6.66e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 57.86  E-value: 6.66e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1243 ESKELKRLVVAESEKSQKLEERLRLLQvETASNSARAAERSSALREEVQSLREEVEKQRVVSENS--RQELASQAERAEE 1320
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQLLPLYQELEalEAELAELPERLEE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1321 LGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQR 1400
Cdd:COG4717    151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1401 ELGELGSLRQKIVEQERAaQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVR 1480
Cdd:COG4717    228 ELEQLENELEAAALEERL-KEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1481 TDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEER-QRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQA 1559
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRiEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEE 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1560 --QRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAkthydakkQQNQKLQEQLQDLEELQKENKELRSEAERL 1637
Cdd:COG4717    387 lrAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE--------ELEEELEELEEELEELEEELEELREELAEL 458

                          410       420       430
                   ....*....|....*....|....*....|....*
gi 1907176315 1638 GRELQQAGLKTK--EAEQTCRHLTAQVRSLEAQVA 1670
Cdd:COG4717    459 EAELEQLEEDGElaELLQELEELKAELRELAEEWA 493
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 272-908 8.36e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 57.75  E-value: 8.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  272 EPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREfanhlqqlqgAFNDLIEEHSKASQ 351
Cdd:TIGR00606  246 ELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE----------QLNDLYHNHQRTVR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  352 EWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQ--LDTLKQEAAKLATDNTQ 429
Cdd:TIGR00606  316 EKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRleLDGFERGPFSERQIKNF 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  430 LQTRVETLEcERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQ 509
Cdd:TIGR00606  396 HTLVIERQE-DEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  510 QRDQEL-ASLKEQAKKEQAQMLQTMQEQEQAaqgLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaivaeaREA 588
Cdd:TIGR00606  475 ELDQELrKAERELSKAEKNSLTETLKKEVKS---LQNEKADLDRKLRKLDQEMEQLNHHTTTRTQ------------MEM 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  589 SLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDnaqtSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVT 668
Cdd:TIGR00606  540 LTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLED----WLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  669 ELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLK----ITKGSLEEEKRRAADALKEQQC-----RATEMEAESRS 739
Cdd:TIGR00606  616 SKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKqramLAGATAVYSQFITQLTDENQSCcpvcqRVFQTEAELQE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  740 LMEQRER-------EQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFE 812
Cdd:TIGR00606  696 FISDLQSklrlapdKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLG 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  813 ARQQEEarygamfQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSAL 892
Cdd:TIGR00606  776 TIMPEE-------ESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELN 848

                          650
                   ....*....|....*.
gi 1907176315  893 QEKMAATNKEVACLKT 908
Cdd:TIGR00606  849 RKLIQDQQEQIQHLKS 864
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1155-1611 1.03e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 57.08  E-value: 1.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1155 EQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAErksslISSLEEEVSILN 1234
Cdd:COG4717     78 EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAE-----LAELPERLEELE 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1235 RQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQ 1314
Cdd:COG4717    153 ERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1315 AERAEELGQELKAWQEKFFQKEQA-LSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQA 1393
Cdd:COG4717    233 ENELEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPA 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1394 elmraqrelgelgslrQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYV 1473
Cdd:COG4717    313 ----------------LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALL 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1474 QELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERqkLTAQVEELSKKLTEHDQASKVQQQK 1553
Cdd:COG4717    377 AEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE--LEEELEELEEELEELEEELEELREE 454

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1554 LKAFQAQRG--ESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQ 1611
Cdd:COG4717    455 LAELEAELEqlEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
mukB PRK04863
chromosome partition protein MukB;
328-674 1.17e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 57.27  E-value: 1.17e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  328 FANHLQQLQGAFNDL---IEEHSKASQEWAEKQARLENELSTALQDKKCLEekneilqgklSQLEDQATRLqespapekg 404
Cdd:PRK04863   346 QQEKIERYQADLEELeerLEEQNEVVEEADEQQEENEARAEAAEEEVDELK----------SQLADYQQAL--------- 406

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  405 evlgDALQLDTLKQEAAKLATDNTQLQTRVETLECErgkqeaQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELE 484
Cdd:PRK04863   407 ----DVQQTRAIQYQQAVQALERAKQLCGLPDLTAD------NAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFE 476

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  485 QASQAQ---GAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:PRK04863   477 QAYQLVrkiAGEVSRSEAWDVARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDEL 556

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  562 EEAAKEQEATRQDHAQQLAIVAEAREaslrerdTARQQLETVeKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 641
Cdd:PRK04863   557 EQLQEELEARLESLSESVSEARERRM-------ALRQQLEQL-QARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQD 628

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1907176315  642 LSQKIGELHACIEASHQEQRQVQARVTELEAQL 674
Cdd:PRK04863   629 VTEYMQQLLERERELTVERDELAARKQALDEEI 661
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 433-775 1.17e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 57.27  E-value: 1.17e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  433 RVETLECERGKQEAQLLAERSRFEDEKQQLA-------SLIADLQSSVSNLS--------QAK--------EELEQASQA 489
Cdd:COG3096    286 RALELRRELFGARRQLAEEQYRLVEMARELEelsaresDLEQDYQAASDHLNlvqtalrqQEKieryqedlEELTERLEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  490 QGAQLTAQLTSMTGLNATLQQRDQELASLKEQ-AKKEQA-QMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEE---- 563
Cdd:COG3096    366 QEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQlADYQQAlDVQQTRAIQYQQAVQALEKARALCGLPDLTPENAEDylaa 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  564 -AAKEQEATRQ--DHAQQLAIVAEAReaslRERDTARQQLETV--EKEKDAKLESLQQQLQAANDARDNAQTsVTQAQQE 638
Cdd:COG3096    446 fRAKEQQATEEvlELEQKLSVADAAR----RQFEKAYELVCKIagEVERSQAWQTARELLRRYRSQQALAQR-LQQLRAQ 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  639 KAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRR 718
Cdd:COG3096    521 LAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAAR 600

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  719 A------ADALKEQQCRATEMEAESRSLME------QREREQKELEQEKAGRKG-LEARIQQLEEAHQAE 775
Cdd:COG3096    601 ApawlaaQDALERLREQSGEALADSQEVTAamqqllEREREATVERDELAARKQaLESQIERLSQPGGAE 670
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 371-913 1.20e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 57.29  E-value: 1.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  371 KKCLEEKNEILQGKLSQLEDQATRLQESPAPEKgEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECE---------- 440
Cdd:TIGR00618  207 TLCTPCMPDTYHERKQVLEKELKHLREALQQTQ-QSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQeavleetqer 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  441 --RGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASL 518
Cdd:TIGR00618  286 inRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVAT 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  519 KEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQ 598
Cdd:TIGR00618  366 SIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAA 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  599 QLETVEKEKDAKlESLQQQLQAANDARdnaqtsvTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQ 678
Cdd:TIGR00618  446 AITCTAQCEKLE-KIHLQESAQSLKER-------EQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPAR 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  679 QKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEE-KRRAADALKEQQCRATEMEAESR--SLMEQREREQKELEQ-E 754
Cdd:TIGR00618  518 QDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSErKQRASLKEQMQEIQQSFSILTQCdnRSKEDIPNLQNITVRlQ 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  755 KAGRKGLEARIQQLEEAHqAETEALRHELAEATASQHRAESEcERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKG 834
Cdd:TIGR00618  598 DLTEKLSEAEDMLACEQH-ALLRKLQPEQDLQDVRLHLQQCS-QELALKLTALHALQLTLTQERVREHALSIRVLPKELL 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  835 EKTGQEVQEEAVEIHSEGQP----GQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLV 910
Cdd:TIGR00618  676 ASRQLALQKMQSEKEQLTYWkemlAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTV 755


                   ...
gi 1907176315  911 LKA 913
Cdd:TIGR00618  756 LKA 758
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1470-1713 1.21e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 1.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1470 EKYvQELAAVRTDAETHLAEMR-QEAQSTSRELEVMTAKYEgakvkvlEERQRFQEERQKLTAQVEELSKKLTEHDQASK 1548
Cdd:TIGR02168  213 ERY-KELKAELRELELALLVLRlEELREELEELQEELKEAE-------EELEELTAELQELEEKLEELRLEVSELEEEIE 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1549 VQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENK 1628
Cdd:TIGR02168  285 ELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1629 ELRSEAERLGRELQQAGL----KTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGkfQVATDALKSREPQVKPQLDLSI 1704
Cdd:TIGR02168  365 AELEELESRLEELEEQLEtlrsKVAQLELQIASLNNEIERLEARLERLEDRRERLQ--QEIEELLKKLEEAELKELQAEL 442


                   ....*....
gi 1907176315 1705 DSLDLSLEE 1713
Cdd:TIGR02168  443 EELEEELEE 451
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 376-593 1.63e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 1.63e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  376 EKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRF 455
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  456 EDEKQQLASLIADLQS-----------SVSNLSQAK------EELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASL 518
Cdd:COG4942    100 EAQKEELAELLRALYRlgrqpplalllSPEDFLDAVrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315  519 KEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRER 593
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGK 254
mukB PRK04863
chromosome partition protein MukB;
429-820 1.63e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 56.89  E-value: 1.63e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  429 QLQTRVETLECERGKQEAQLLAERSRFEDEKQQLaSLIADLQSSVSNLS---------QAKEELEQASQAQG--AQLTAQ 497
Cdd:PRK04863   841 QLNRRRVELERALADHESQEQQQRSQLEQAKEGL-SALNRLLPRLNLLAdetladrveEIREQLDEAEEAKRfvQQHGNA 919

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  498 LTSMTGLNATLQQRDQELASLKEQAKKEQaQMLQTMQEQEQAAQGLRQQVEQLSSSLKlkEQQLEEAAKEQEATRQDHAQ 577
Cdd:PRK04863   920 LAQLEPIVSVLQSDPEQFEQLKQDYQQAQ-QTQRDAKQQAFALTEVVQRRAHFSYEDA--AEMLAKNSDLNEKLRQRLEQ 996

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  578 qlaivAEAreaslrERDTARQQLetveKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSqkigeLHACIEAsh 657
Cdd:PRK04863   997 -----AEQ------ERTRAREQL----RQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLG-----VPADSGA-- 1054

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  658 qeQRQVQARVTELEAQLKAEQQKTTEREKVVQ----EKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEM 733
Cdd:PRK04863  1055 --EERARARRDELHARLSANRSRRNQLEKQLTfceaEMDNLTKKLRKLERDYHEMREQVVNAKAGWCAVLRLVKDNGVER 1132

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  734 EAESR-----SLMEQREREQKELEQEKAGRKGLEARIQQL---EEAHQAET-------------EALRHELAEAT---AS 789
Cdd:PRK04863  1133 RLHRRelaylSADELRSMSDKALGALRLAVADNEHLRDVLrlsEDPKRPERkvqfyiavyqhlrERIRQDIIRTDdpvEA 1212

                          410       420       430
                   ....*....|....*....|....*....|.
gi 1907176315  790 QHRAESECERLIREVESRQKRFEARQQEEAR 820
Cdd:PRK04863  1213 IEQMEIELSRLTEELTSREQKLAISSESVAN 1243
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 275-752 1.94e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 56.72  E-value: 1.94e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  275 ELEELRGKNESltvRLHETLKQCQNLKTEKSQMDRKI----SQLSEENG---DLSFKVREFANHLQQLQGAFNDLIEEHS 347
Cdd:pfam01576   72 ELEEILHELES---RLEEEEERSQQLQNEKKKMQQHIqdleEQLDEEEAarqKLQLEKVTTEAKIKKLEEDILLLEDQNS 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  348 KASQEWAEKQARLeNELSTALQDKkclEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDN 427
Cdd:pfam01576  149 KLSKERKLLEERI-SEFTSNLAEE---EEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQI 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  428 TQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGA-------------QL 494
Cdd:pfam01576  225 AELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKaekqrrdlgeeleAL 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  495 TAQLTSMTGLNATLQ----QRDQELASLK----EQAKKEQAQMLQTMQEQEQAAQGLRQQVEQlsssLKLKEQQLEEAAK 566
Cdd:pfam01576  305 KTELEDTLDTTAAQQelrsKREQEVTELKkaleEETRSHEAQLQEMRQKHTQALEELTEQLEQ----AKRNKANLEKAKQ 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  567 EQEATRQDHAQQLAIVAEAREASLRERDTARQQL----------ETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQ 636
Cdd:pfam01576  381 ALESENAELQAELRTLQQAKQDSEHKRKKLEGQLqelqarlsesERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLS 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  637 QEKAELSQKIGELHACIEASHQEQRQVQARVTELEA-------QLKAEQQKTTEREKVVQE-KAQLQEQLRALEESLKIT 708
Cdd:pfam01576  461 KDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDernslqeQLEEEEEAKRNVERQLSTlQAQLSDMKKKLEEDAGTL 540

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1907176315  709 KGsLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELE 752
Cdd:pfam01576  541 EA-LEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELD 583
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 343-1090 2.09e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.52  E-value: 2.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  343 IEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQAtrlqespapekgevlgdalqlDTLKQEAAK 422
Cdd:pfam02463  158 IEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAK---------------------KALEYYQLK 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  423 LATDNTQLQTRVETLECERGKQEAQLLAERsrfEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMT 502
Cdd:pfam02463  217 EKLELEEEYLLYLDYLKLNEERIDLLQELL---RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAK 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  503 GLNATLQQRDQELaSLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLaiv 582
Cdd:pfam02463  294 EEEELKSELLKLE-RRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLE--- 369

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  583 aEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQ 662
Cdd:pfam02463  370 -QLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTE 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  663 VQARVTELEAqLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLME 742
Cdd:pfam02463  449 EKEELEKQEL-KLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISA 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  743 QREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAE-----------------ATASQHRAESECERLIREVE 805
Cdd:pfam02463  528 HGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALtelplgarklrllipklKLPLKSIAVLEIDPILNLAQ 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  806 SRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKL 885
Cdd:pfam02463  608 LDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAES 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  886 VDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPFS-STHAAVKAMEREAEQM 964
Cdd:pfam02463  688 ELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEeEEKSRLKKEEKEEEKS 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  965 GGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLaQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALT 1044
Cdd:pfam02463  768 ELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEEL-KEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQ 846

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*.
gi 1907176315 1045 EKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPA 1090
Cdd:pfam02463  847 KLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKE 892
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
584-1314 3.46e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.84  E-value: 3.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  584 EAREASLRE------RDTARQQLETVEKEKDAKLESLQQQLQAAndarDNAQTSVTQAQQEKAELSQKIGELHACIEASH 657
Cdd:PRK03918   145 ESREKVVRQilglddYENAYKNLGEVIKEIKRRIERLEKFIKRT----ENIEELIKEKEKELEEVLREINEISSELPELR 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  658 QEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLE--EEKRRAADALKEQQCRATEMEA 735
Cdd:PRK03918   221 EELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEelEEKVKELKELKEKAEEYIKLSE 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  736 ESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAhQAETEALRHElaeatasqhraESECERLIREVESRQKRFEARQ 815
Cdd:PRK03918   301 FYEEYLDELREIEKRLSRLEEEINGIEERIKELEEK-EERLEELKKK-----------LKELEKRLEELEERHELYEEAK 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  816 QEearygamfQEQLMALKGEKTGQEVQeeaveihsegqpgqqqsqlaqlhaslaKAIQQVQEKEVRAQKLVDDLSALQEK 895
Cdd:PRK03918   369 AK--------KEELERLKKRLTGLTPE---------------------------KLEKELEELEKAKEEIEEEISKITAR 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  896 MAATNKEVACLKTLVLKageqqetasLELLKEPPRAANRASDQlgEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAAL 975
Cdd:PRK03918   414 IGELKKEIKELKKAIEE---------LKKAKGKCPVCGRELTE--EHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  976 IKSQGQQQEERgqqerevaRLTQERGQAQadlaQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAK 1055
Cdd:PRK03918   483 RELEKVLKKES--------ELIKLKELAE----QLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1056 LRGQEaaqrTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDasgpgtqsetagktdapgpelqALRAEISKLEQQCQQQ 1135
Cdd:PRK03918   551 LEELK----KKLAELEKKLDELEEELAELLKELEELGFESVE----------------------ELEERLKELEPFYNEY 604

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1136 QqqveglthSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAqdhskAEEEWKaqvaRGQQE 1215
Cdd:PRK03918   605 L--------ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY-----SEEEYE----ELREE 667

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1216 AERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvaESEKSQKLEERLRLLQvetasnsaRAAERSSALREEVQSLRE 1295
Cdd:PRK03918   668 YLELSRELAGLRAELEELEKRREEIKKTLEKLKE----ELEEREKAKKELEKLE--------KALERVEELREKVKKYKA 735

                          730
                   ....*....|....*....
gi 1907176315 1296 EVEKQrvvSENSRQELASQ 1314
Cdd:PRK03918   736 LLKER---ALSKVGEIASE 751
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 491-722 3.51e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 3.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  491 GAQLTAQLTSMTGLNATLQQRDQELASLK---EQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKE 567
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEkelAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  568 QEATRQDHAQQLAIVAEAREASLRERDTARQQLeTVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIG 647
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRQPPLAL-LLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315  648 ELHACIEASHQEQRQVQARvteLEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADA 722
Cdd:COG4942    171 AERAELEALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
620-1169 4.17e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 4.17e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  620 AANDARDNAQTSVTQAQQEKAELSQKigELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLR 699
Cdd:PRK02224   177 GVERVLSDQRGSLDQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  700 ALEES---LKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEE------ 770
Cdd:PRK02224   255 TLEAEiedLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDrleecr 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  771 ----AHQAETEALRH---------------------ELAEATASQHRAESECERLIREVESRQKRFE---ARQQEEARYG 822
Cdd:PRK02224   335 vaaqAHNEEAESLREdaddleeraeelreeaaelesELEEAREAVEDRREEIEELEEEIEELRERFGdapVDLGNAEDFL 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  823 AMFQEQLMALKGE--------KTGQEVQEEAVEIHSEGQ-PGQQQSQLAQLHASlakaiqQVQEKEVRAQKLVDDLSALQ 893
Cdd:PRK02224   415 EELREERDELREReaeleatlRTARERVEEAEALLEAGKcPECGQPVEGSPHVE------TIEEDRERVEELEAELEDLE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  894 EKMAATNKEVACLKTLVlkageqqetaslELLKEPPRAANRASD--QLGEQQgrpfsstHAAVKAMEREAEQMGGELERL 971
Cdd:PRK02224   489 EEVEEVEERLERAEDLV------------EAEDRIERLEERREDleELIAER-------RETIEEKRERAEELRERAAEL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  972 RAAliksqgqqqeergqqerevARLTQERGQAQADLAQEKAAK-AELEMRLQnTLNEQRVEFAALQEALAhALTEKEGTD 1050
Cdd:PRK02224   550 EAE-------------------AEEKREAAAEAEEEAEEAREEvAELNSKLA-ELKERIESLERIRTLLA-AIADAEDEI 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1051 QELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQ 1130
Cdd:PRK02224   609 ERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVEN 688

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1907176315 1131 QCQQQQqqveglthSLKSERACRAEQDKALETLQGQLEE 1169
Cdd:PRK02224   689 ELEELE--------ELRERREALENRVEALEALYDEAEE 719
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1387-1629 5.21e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.38  E-value: 5.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1387 AAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELD 1466
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-ELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1467 QAREKYVQELAAVRTDAETHLAEMrQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQA 1546
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1547 SKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEhyklqmekakTHYDAKKQQNQKLQEQLQDLEELQKE 1626
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELA----------AELAELQQEAEELEALIARLEAEAAA 238


                   ...
gi 1907176315 1627 NKE 1629
Cdd:COG4942    239 AAE 241
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
407-640 5.31e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 55.02  E-value: 5.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  407 LGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSR-----FEDEKQQLASLIADLQSSvsnLSQAKE 481
Cdd:COG3206    157 LAEAYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKnglvdLSEEAKLLLQQLSELESQ---LAEARA 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  482 ELEQAsQAQGAQLTAQLTSMTGLNATLQQrDQELASLKEQ---AKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKlke 558
Cdd:COG3206    234 ELAEA-EARLAALRAQLGSGPDALPELLQ-SPVIQQLRAQlaeLEAELAELSARYTPNHPDVIALRAQIAALRAQLQ--- 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  559 QQLEEAAKEQEATRQdhaqqlaiVAEAREASLRER-DTARQQLETVeKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQ 637
Cdd:COG3206    309 QEAQRILASLEAELE--------ALQAREASLQAQlAQLEARLAEL-PELEAELRRLEREVEVARELYESLLQRLEEARL 379


                   ...
gi 1907176315  638 EKA 640
Cdd:COG3206    380 AEA 382
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1215-1536 5.36e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 54.74  E-value: 5.36e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1215 EAERKSSLISSLEEEVSILNRQVLEKeGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLR 1294
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEK-FEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAME 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1295 EEVEKQRVVSENSRQELasQAERAEELGQELKAWQEkffqkeqaLSALQLEHTSTQALVSELLPAkhlcqqlqaeqaAAE 1374
Cdd:pfam17380  346 RERELERIRQEERKREL--ERIRQEEIAMEISRMRE--------LERLQMERQQKNERVRQELEA------------ARK 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1375 KRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSML-------KKAHGLLAEEN 1447
Cdd:pfam17380  404 VKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLrqqeeerKRKKLELEKEK 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1448 RGLGERANLGRQFLEVELDQAREKYVQElaavRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQ 1527
Cdd:pfam17380  484 RDRKRAEEQRRKILEKELEERKQAMIEE----ERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMR 559


                   ....*....
gi 1907176315 1528 KLTAQVEEL 1536
Cdd:pfam17380  560 KATEERSRL 568
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 218-1087 5.72e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.98  E-value: 5.72e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  218 KKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQC 297
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  298 QNLKTEKSQ--------MDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQ 369
Cdd:pfam02463  260 IEKEEEKLAqvlkenkeEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  370 DKKCLEEKnEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQtrvetlecERGKQEAQLL 449
Cdd:pfam02463  340 LEKELKEL-EIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELK--------SEEEKEAQLL 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  450 AERSrfedekQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQM 529
Cdd:pfam02463  411 LELA------RQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  530 LQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDA 609
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  610 KLeslqqqLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQ 689
Cdd:pfam02463  565 KL------VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  690 EKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE 769
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLE 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  770 EahqAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEaveih 849
Cdd:pfam02463  719 A---EELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEE----- 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  850 segqpgQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEpp 929
Cdd:pfam02463  791 ------EKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE-- 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  930 raaNRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQ 1009
Cdd:pfam02463  863 ---ITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315 1010 EKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKE 1087
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1397-1644 5.93e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 5.93e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1397 RAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhgllaEENRGLGERANLGRQFLEVELDQARekyVQEL 1476
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERL-----AELEYLRAALRLWFAQRRLELLEAE---LEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1477 AAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEErqrfqeerqkLTAQVEELSKKLTEHDQASKVQQQKLKA 1556
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQ----------LEREIERLERELEERERRRARLEALLAA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1557 FQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEhyklqmekakthyDAKKQQNQKLQEQLQDLEELQKENKELRSEAER 1636
Cdd:COG4913    371 LGLPLPASAEEFAALRAEAAALLEALEEELEALE-------------EALAEAEAALRDLRRELRELEAEIASLERRKSN 437


                   ....*...
gi 1907176315 1637 LGRELQQA 1644
Cdd:COG4913    438 IPARLLAL 445
46 PHA02562
endonuclease subunit; Provisional
 305-567 6.11e-07

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 54.64  E-value: 6.11e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  305 SQMDR----KISQLSEENGDLSFKVrefaNHLQQLQGAFNDLIEEHSKAS-QEWAEKQARLENELSTALQDKKCLEEKNE 379
Cdd:PHA02562   166 SEMDKlnkdKIRELNQQIQTLDMKI----DHIQQQIKTYNKNIEEQRKKNgENIARKQNKYDELVEEAKTIKAEIEELTD 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  380 ILQGKLSQLEDQATRLQEspapekgevlgdalqldtLKQEAAKLATDNTQLQTRVETLE----CERGKQeaQLLAERSRF 455
Cdd:PHA02562   242 ELLNLVMDIEDPSAALNK------------------LNTAAAKIKSKIEQFQKVIKMYEkggvCPTCTQ--QISEGPDRI 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  456 EDEKQQlaslIADLQSSVSNLSQAKEELEQasqaQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMlqtmqE 535
Cdd:PHA02562   302 TKIKDK----LKELQHSLEKLDTAIDELEE----IMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAI-----E 368

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1907176315  536 QEQAAQGLR-QQVEQLSSSLKLKEQQLEEAAKE 567
Cdd:PHA02562   369 ELQAEFVDNaEELAKLQDELDKIVKTKSELVKE 401
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1211-1645 6.22e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 54.96  E-value: 6.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1211 RGQQEAERKSSLISSLEEEVSILNRQVLEKEGE----SKELKRLVVAESEKSQKLE---ERLRLLQvetasNSARAAERS 1283
Cdd:COG3096    275 RHANERRELSERALELRRELFGARRQLAEEQYRlvemARELEELSARESDLEQDYQaasDHLNLVQ-----TALRQQEKI 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1284 SALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLC 1363
Cdd:COG3096    350 ERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARALC 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1364 qqlqaeqaaaekrfrEELEQSKQAAGGLQAELMRAQRELGE-LGSLRQKIVEQERAAQQlraekasYAEQLSMLKKAHGL 1442
Cdd:COG3096    430 ---------------GLPDLTPENAEDYLAAFRAKEQQATEeVLELEQKLSVADAARRQ-------FEKAYELVCKIAGE 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1443 LaeenrglgERANLGRQFLEVeLDQAREKyvQELAAVRTDAETHLAEMRQEAQStSRELEVMTAKYEGAKVKVLEERQRF 1522
Cdd:COG3096    488 V--------ERSQAWQTAREL-LRRYRSQ--QALAQRLQQLRAQLAELEQRLRQ-QQNAERLLEEFCQRIGQQLDAAEEL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1523 QEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGE-SQQEVQ--RLQTQLNELQAQLSQkeqaaehyklqmeka 1599
Cdd:COG3096    556 EELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKElAARAPAwlAAQDALERLREQSGE--------------- 620

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 1907176315 1600 ktHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLG---RELQQAG 1645
Cdd:COG3096    621 --ALADSQEVTAAMQQLLEREREATVERDELAARKQALEsqiERLSQPG 667
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
533-775 6.91e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.64  E-value: 6.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  533 MQEQEQAAQGLRQQVEQLssslklkEQQLEEAAKEQEATRQDHAqqlaIVAeareaslrerdtarqqLETVEKEKDAKLE 612
Cdd:COG3206    170 REEARKALEFLEEQLPEL-------RKELEEAEAALEEFRQKNG----LVD----------------LSEEAKLLLQQLS 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  613 SLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhacieASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQeka 692
Cdd:COG3206    223 ELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL-----LQSPVIQQLRAQLAELEAELAELSARYTPNHPDVI--- 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  693 QLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLME---QREREQKELEQE-KAGRKGLEARIQQL 768
Cdd:COG3206    295 ALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAelpELEAELRRLEREvEVARELYESLLQRL 374


                   ....*..
gi 1907176315  769 EEAHQAE 775
Cdd:COG3206    375 EEARLAE 381
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 444-906 7.62e-07

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 54.42  E-value: 7.62e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  444 QEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQltsmtglnATLQQRDQELASLKEQAK 523
Cdd:PRK10246   217 QVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDELQQEASRRQQALQQAL--------AAEEKAQPQLAALSLAQP 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  524 KEQAQML-QTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEE-------AAKEQEATRQDHAQQLAIVAEAR--------- 586
Cdd:PRK10246   289 ARQLRPHwERIQEQSAALAHTRQQIEEVNTRLQSTMALRARirhhaakQSAELQAQQQSLNTWLAEHDRFRqwnnelagw 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  587 EASLRERDTARQQLETVEkekdAKLESLQQQLQAAND------ARDNAQTSVTQAQQEKaeLSQKIGELHACIEASHQEQ 660
Cdd:PRK10246   369 RAQFSQQTSDREQLRQWQ----QQLTHAEQKLNALPAitltltADEVAAALAQHAEQRP--LRQRLVALHGQIVPQQKRL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  661 RQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKgSLEEEKRRAADALKEQQCRATEMEAESrsl 740
Cdd:PRK10246   443 AQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIK-DLEAQRAQLQAGQPCPLCGSTSHPAVE--- 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  741 meqrEREQKELEQEKAGRKGLEARIQQLEEahqaETEALRHELAEATASQHRAESECERLIREvesRQKRFEARQQEEAR 820
Cdd:PRK10246   519 ----AYQALEPGVNQSRLDALEKEVKKLGE----EGAALRGQLDALTKQLQRDESEAQSLRQE---EQALTQQWQAVCAS 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  821 YGAMFQEQlMALKGEKTGQEVQEEAVEihsegQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATN 900
Cdd:PRK10246   588 LNITLQPQ-DDIQPWLDAQEEHERQLR-----LLSQRHELQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQED 661


                   ....*.
gi 1907176315  901 KEVACL 906
Cdd:PRK10246   662 EEASWL 667
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
253-649 8.08e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.39  E-value: 8.08e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  253 QQRIDHLALLNEKQAASSQEPSELEELRGKNESLtVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHL 332
Cdd:COG4717     91 AELQEELEELEEELEELEAELEELREELEKLEKL-LQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELE 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  333 QQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQ-ESPAPEKGEVLGDAL 411
Cdd:COG4717    170 AELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEnELEAAALEERLKEAR 249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 491
Cdd:COG4717    250 LLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALG 329

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  492 AQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLrQQVEQLSSSLKLKEQQLEEAAKEQEAT 571
Cdd:COG4717    330 LPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGV-EDEEELRAALEQAEEYQELKEELEELE 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  572 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTS--VTQAQQEKAELSQKIGEL 649
Cdd:COG4717    409 EQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDgeLAELLQELEELKAELREL 488
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 294-882 9.01e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.28  E-value: 9.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  294 LKQCQNLKTEKSQMDRKISQLSEENGDLsfkvrefaNHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQD--- 370
Cdd:TIGR00606  500 KKEVKSLQNEKADLDRKLRKLDQEMEQL--------NHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfpn 571

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  371 KKCLEEKNEILQGKLSQLEDQATRLQESPAPekgevlGDALQLDTLKQEAAKLATDNTQLQTRVETLECErgKQEAQLLA 450
Cdd:TIGR00606  572 KKQLEDWLHSKSKEINQTRDRLAKLNKELAS------LEQNKNHINNELESKEEQLSSYEDKLFDVCGSQ--DEESDLER 643

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  451 ERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQA---------SQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQ 521
Cdd:TIGR00606  644 LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCcpvcqrvfqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK 723

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  522 AKKE---QAQMLQT-MQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAtrqdhaqqlaIVAEAREASLRERD-TA 596
Cdd:TIGR00606  724 RRDEmlgLAPGRQSiIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGT----------IMPEEESAKVCLTDvTI 793

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  597 RQQLETVEKEKDAKLESLQQQLQAANDARdnAQTSVTQAQQEKAE----LSQKIGELHACIEASHQEQRQVQARVTELEA 672
Cdd:TIGR00606  794 MERFQMELKDVERKIAQQAAKLQGSDLDR--TVQQVNQEKQEKQHeldtVVSKIELNRKLIQDQQEQIQHLKSKTNELKS 871

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  673 QLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELE 752
Cdd:TIGR00606  872 EKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVK 951

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  753 QEKAGRKGLEARIQQLEEAHQAETEalrHELAEATASQHRAESECERLIREVESRQKRFEARQQEEarygAMFQEQLMAL 832
Cdd:TIGR00606  952 NIHGYMKDIENKIQDGKDDYLKQKE---TELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQE----RWLQDNLTLR 1024

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907176315  833 KGEKTGQEVQEEAVEihSEGQPGQQQ-SQLAQLHASLAKAIQQVQEKEVRA 882
Cdd:TIGR00606 1025 KRENELKEVEEELKQ--HLKEMGQMQvLQMKQEHQKLEENIDLIKRNHVLA 1073
PRK11281 PRK11281
mechanosensitive channel MscK;
412-712 9.12e-07

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 54.53  E-value: 9.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  412 QLDTLKQEAAKLATDNTQLQTRVETLEC--ERGKQEAQLLAERSRFEDEKQQLASLIADLQS-SVSNLSQAKEELEQASQ 488
Cdd:PRK11281    44 QLDALNKQKLLEAEDKLVQQDLEQTLALldKIDRQKEETEQLKQQLAQAPAKLRQAQAELEAlKDDNDEETRETLSTLSL 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  489 AQ-GAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQM---LQTMQEQEQAAQGLRQQVEQLSSSLKLK---EQQL 561
Cdd:PRK11281   124 RQlESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALyanSQRLQQIRNLLKGGKVGGKALRPSQRVLlqaEQAL 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  562 EEAAKEQEATRQDHAQQLAIVAEAReaslRERDTARQQLetvekekdakLESLQQQLQAANDARDNAQTSVTQAQQEKAE 641
Cdd:PRK11281   204 LNAQNDLQRKSLEGNTQLQDLLQKQ----RDYLTARIQR----------LEHQLQLLQEAINSKRLTLSEKTVQEAQSQD 269

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315  642 LSQKIGE---LHACIEASHQ-EQRQVQArvTELEAQLKAEQQKTtereKVVQEKAQlQEQlRALEESLKITKGSL 712
Cdd:PRK11281   270 EAARIQAnplVAQELEINLQlSQRLLKA--TEKLNTLTQQNLRV----KNWLDRLT-QSE-RNIKEQISVLKGSL 336
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 206-777 1.03e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.20  E-value: 1.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  206 ILQTPQFQMRRLKKQLADERSNRDDLELELSESLKLLTekdaqiamMQQRIDHLALLNEKQAA----SSQEPSELEELRG 281
Cdd:TIGR00618  312 IHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT--------LHSQEIHIRDAHEVATSireiSCQQHTLTQHIHT 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  282 KNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVRefANHLQQLQGAFNDLIEEHSKASQEWAEKQARLE 361
Cdd:TIGR00618  384 LQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAH--AKKQQELQQRYAELCAAAITCTAQCEKLEKIHL 461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  362 NELSTALQDKKCLEEKNEILQGKLSQL----EDQATRLQESPAPEKGEVLGDALQLdTLKQEAAKLATDNTQLQTRVETL 437
Cdd:TIGR00618  462 QESAQSLKEREQQLQTKEQIHLQETRKkavvLARLLELQEEPCPLCGSCIHPNPAR-QDIDNPGPLTRRMQRGEQTYAQL 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  438 ECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASqaqgaQLTAQLTSMTGLNATLQQRDQELAS 517
Cdd:TIGR00618  541 ETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQ-----NITVRLQDLTEKLSEAEDMLACEQH 615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  518 LKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSS-SLKLKEQQLEEAAKeqeATRQDHAQQLAIvaeaREASLRERDTA 596
Cdd:TIGR00618  616 ALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHAlQLTLTQERVREHAL---SIRVLPKELLAS----RQLALQKMQSE 688

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  597 RQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACI-EASHQEQRQVQARVTELE---A 672
Cdd:TIGR00618  689 KEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLkELMHQARTVLKARTEAHFnnnE 768

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  673 QLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELE 752
Cdd:TIGR00618  769 EVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEIT 848

                          570       580
                   ....*....|....*....|....*
gi 1907176315  753 QEKagrKGLEARIQQLEEAHQAETE 777
Cdd:TIGR00618  849 HQL---LKYEECSKQLAQLTQEQAK 870
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1117-1637 1.08e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 1.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEqdkaLETLQGQLEEKarelghnQAASASAQRELQALRAKAQ 1196
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE----LETLEAEIEDL-------RETIAETEREREELAEEVR 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQvlekegeskelkrlvvaESEKSQKLEERlRLLQVETASNS 1276
Cdd:PRK02224   283 DLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDR-----------------DEELRDRLEEC-RVAAQAHNEEA 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1277 ARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1356
Cdd:PRK02224   345 ESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDEL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1357 LPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGElgsLRQKIVEQERAAQQLRAEKASYAEQLSML 1436
Cdd:PRK02224   425 REREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEE---DRERVEELEAELEDLEEEVEEVEERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1437 KKAHGLLAEENRgLGERANLGRQFLEVELDQAREKYVQeLAAVRTDAETHLAEMR-QEAQSTSRELEVMTAKYEgakVKV 1515
Cdd:PRK02224   502 EDLVEAEDRIER-LEERREDLEELIAERRETIEEKRER-AEELRERAAELEAEAEeKREAAAEAEEEAEEAREE---VAE 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1516 LEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQA--------QLSQKEQ 1587
Cdd:PRK02224   577 LNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAefdearieEAREDKE 656

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907176315 1588 AAEHYKLQMEKAKTHYDAKKQQNQK----LQEQLQDLEELQKENKELRSEAERL 1637
Cdd:PRK02224   657 RAEEYLEQVEEKLDELREERDDLQAeigaVENELEELEELRERREALENRVEAL 710
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1525-1693 1.12e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1525 ERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEhyklQMEKAKTHYD 1604
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA----RLEQDIARLE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1605 AKKQQNQKLQEQLqdLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQV 1684
Cdd:COG1196    309 ERRRELEERLEEL--EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386


                   ....*....
gi 1907176315 1685 ATDALKSRE 1693
Cdd:COG1196    387 ELLEALRAA 395
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1223-1679 1.31e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.49  E-value: 1.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1223 ISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAaerssalreevqslrEEVEKQRV 1302
Cdd:TIGR04523  105 LSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKY---------------NDLKKQKE 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1303 VSENSRQELASQAERAEelgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKhlcqqlqaeqaAAEKRFREELE 1382
Cdd:TIGR04523  170 ELENELNLLEKEKLNIQ---KNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELK-----------KQNNQLKDNIE 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1383 QSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQ-----------QLRAEKASYAEQLSMLK--KAHGLLAEENRG 1449
Cdd:TIGR04523  236 KKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQkeleqnnkkikELEKQLNQLKSEISDLNnqKEQDWNKELKSE 315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1450 LGERANLGRQfLEVELDQArEKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEgakvKVLEERQRFQEERQKL 1529
Cdd:TIGR04523  316 LKNQEKKLEE-IQNQISQN-NKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNL 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1530 TAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQ 1609
Cdd:TIGR04523  390 ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ 469

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176315 1610 NQKLQEQL----QDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1679
Cdd:TIGR04523  470 LKVLSRSInkikQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDL 543
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1186-1669 1.32e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.91  E-value: 1.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1186 RELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLvvaeSEKSQKLEERL 1265
Cdd:PRK03918   172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL----KEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1266 RLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVsensrQELASQAERAEELGQELKAWQEKFFQKEQALSALQLE 1345
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL-----KELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1346 HTSTQALVSELLPAKHLCQQLQAEQAAAEKRFrEELEQSKQA---AGGLQAELMRAQRELG---------ELGSLRQKIV 1413
Cdd:PRK03918   323 INGIEERIKELEEKEERLEELKKKLKELEKRL-EELEERHELyeeAKAKKEELERLKKRLTgltpeklekELEELEKAKE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1414 EQERAAQQLRAEKASYAEQLSMLKKAhglLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAEThLAEMRQE 1493
Cdd:PRK03918   402 EIEEEISKITARIGELKKEIKELKKA---IEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKE-IEEKERK 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1494 AQSTSRELEvmtakyegakvKVLEERQRFQEERqKLTAQVEELSKKLTEHDqaSKVQQQKLKAFQAQRGES---QQEVQR 1570
Cdd:PRK03918   478 LRKELRELE-----------KVLKKESELIKLK-ELAEQLKELEEKLKKYN--LEELEKKAEEYEKLKEKLiklKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1571 LQTQLNELQAQLSQKEQAAEHYK-LQMEKAKTHYDAKK---QQNQKLQEQLQDLEELQKENKELR---SEAERLGRELQQ 1643
Cdd:PRK03918   544 LKKELEKLEELKKKLAELEKKLDeLEEELAELLKELEElgfESVEELEERLKELEPFYNEYLELKdaeKELEREEKELKK 623

                          490       500
                   ....*....|....*....|....*.
gi 1907176315 1644 AGLKTKEAEQTCRHLTAQVRSLEAQV 1669
Cdd:PRK03918   624 LEEELDKAFEELAETEKRLEELRKEL 649
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1452-1644 1.47e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.48  E-value: 1.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1452 ERANLGRQFLEVELDQAREKYVQ-ELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLT 1530
Cdd:COG3206    171 EEARKALEFLEEQLPELRKELEEaEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLG 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1531 AQVEELSKKLTEHDQASKVQQ-----QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAehyklqMEKAKTHYDA 1605
Cdd:COG3206    251 SGPDALPELLQSPVIQQLRAQlaeleAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRI------LASLEAELEA 324

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1907176315 1606 KKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQA 1644
Cdd:COG3206    325 LQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVA 363
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 405-1081 1.99e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 53.26  E-value: 1.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  405 EVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAE----------RSRFEDEKQQLASLIADLQSSVS 474
Cdd:pfam01576    6 EMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAEtelcaeaeemRARLAARKQELEEILHELESRLE 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  475 NLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLqTMQEQEQAAQGLRQQVEQLSSSL 554
Cdd:pfam01576   86 EEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDIL-LLEDQNSKLSKERKLLEERISEF 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  555 KLKEQQLEEAAKEQEATRQDHAQQLAIVaearEASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQ 634
Cdd:pfam01576  165 TSNLAEEEEKAKSLSKLKNKHEAMISDL----EERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAK 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  635 AQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQEQLRA----LEESLKITKG 710
Cdd:pfam01576  241 KEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERA---ARNKAEKQRRDLGEELEAlkteLEDTLDTTAA 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  711 SLEEEKRRAADALKEQQCRATEMEAESRSLMEQRERE-------QKELEQEKAGRKGLEARIQQLEEAhqaetealRHEL 783
Cdd:pfam01576  318 QQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHtqaleelTEQLEQAKRNKANLEKAKQALESE--------NAEL 389

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  784 AEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGE---KTGQEVQEEAVEIHSEGQPGQQQSQ 860
Cdd:pfam01576  390 QAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSElesVSSLLNEAEGKNIKLSKDVSSLESQ 469

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  861 LAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKM-------AATNKEVACLKTLV--LKAGEQQETASLELLKEPPRA 931
Cdd:pfam01576  470 LQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLeeeeeakRNVERQLSTLQAQLsdMKKKLEEDAGTLEALEEGKKR 549

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  932 ANRASDQLGEQqgrpFSSTHAAVKAMEREAEQMGGELE----------RLRAALIKSQGQQQEERGQQEREVARLTQERG 1001
Cdd:pfam01576  550 LQRELEALTQQ----LEEKAAAYDKLEKTKNRLQQELDdllvdldhqrQLVSNLEKKQKKFDQMLAEEKAISARYAEERD 625

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1002 QAQADlAQEKAAKAELEMRLQNTLNEQRVEF----AALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQL 1077
Cdd:pfam01576  626 RAEAE-AREKETRALSLARALEEALEAKEELertnKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEEL 704


                   ....
gi 1907176315 1078 KIQL 1081
Cdd:pfam01576  705 EDEL 708
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1375-1702 2.10e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 2.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1375 KRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGER- 1453
Cdd:PRK03918   182 EKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKi 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1454 ANLGRQFLEVELD-QAREKYVQELAAVRTDAETH--LAEMRQEAQSTSRELEVMTAKYEgAKVKVLEERQrfqEERQKLT 1530
Cdd:PRK03918   262 RELEERIEELKKEiEELEEKVKELKELKEKAEEYikLSEFYEEYLDELREIEKRLSRLE-EEINGIEERI---KELEEKE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1531 AQVEELSKKLTEHDQASKVQQQKLKAFQaqrgesqqEVQRLQTQLNELQAQLSQKEqaAEHYKLQMEKAKThydAKKQQN 1610
Cdd:PRK03918   338 ERLEELKKKLKELEKRLEELEERHELYE--------EAKAKKEELERLKKRLTGLT--PEKLEKELEELEK---AKEEIE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1611 QKLQEQLQDLEELQKENKELRSEAERL----------GRELQQaglktKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLG 1680
Cdd:PRK03918   405 EEISKITARIGELKKEIKELKKAIEELkkakgkcpvcGRELTE-----EHRKELLEEYTAELKRIEKELKEIEEKERKLR 479

                          330       340
                   ....*....|....*....|..
gi 1907176315 1681 KFQVATDALKSREPQVKPQLDL 1702
Cdd:PRK03918   480 KELRELEKVLKKESELIKLKEL 501
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1146-1676 2.19e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 53.26  E-value: 2.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1146 LKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQalrakaqdhsKAEEEWKAQVARGQQEAERKSSLISS 1225
Cdd:pfam01576  196 LKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLA----------KKEEELQAALARLEEETAQKNNALKK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1226 LEEevsiLNRQVLEKEgESKELKRLVVAESEKSQK-LEERLRLLQVE---TASNSARAAERSSALREEVQSLREEVEKQR 1301
Cdd:pfam01576  266 IRE----LEAQISELQ-EDLESERAARNKAEKQRRdLGEELEALKTEledTLDTTAAQQELRSKREQEVTELKKALEEET 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1302 VVSENSRQELASQAERA-EELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREE 1380
Cdd:pfam01576  341 RSHEAQLQEMRQKHTQAlEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQAR 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1381 LEQSKQAAGGLQAELMRAQRELGELGSLrqkIVEQERAAQQLRAEKASYAEQLsmlKKAHGLLAEENRglgERANLGRQF 1460
Cdd:pfam01576  421 LSESERQRAELAEKLSKLQSELESVSSL---LNEAEGKNIKLSKDVSSLESQL---QDTQELLQEETR---QKLNLSTRL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1461 LEVELDQAR-EKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKvkvlEERQRFQEERQKLTAQVEELSKK 1539
Cdd:pfam01576  492 RQLEDERNSlQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALE----EGKKRLQRELEALTQQLEEKAAA 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1540 LTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQ----NQKLQE 1615
Cdd:pfam01576  568 YDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRalslARALEE 647

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176315 1616 QLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQL 1676
Cdd:pfam01576  648 ALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL 708
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1008-1542 2.31e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 2.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1008 AQEKAAKAELEMRLQNTLnEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLvkkeke 1087
Cdd:COG4913    260 LAERYAAARERLAELEYL-RAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQI------ 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1088 hpaggasgedasgpgtqsetagkTDAPGPELQALRAEISKLEQQCQQQQQQveglthslkseracRAEQDKALETLQGQL 1167
Cdd:COG4913    333 -----------------------RGNGGDRLEQLEREIERLERELEERERR--------------RARLEALLAALGLPL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1168 EEKARELGHNQAASASAQRELQALRAKAQDhskAEEEWKAQVARGQQEAERKSSLISSLEEEVS------ILNRQVLEKE 1241
Cdd:COG4913    376 PASAEEFAALRAEAAALLEALEEELEALEE---ALAEAEAALRDLRRELRELEAEIASLERRKSniparlLALRDALAEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1242 -----------GESKELK-------------------RLVVAESEKSQ--------KLEERLRLLQVETASNSARAAE-- 1281
Cdd:COG4913    453 lgldeaelpfvGELIEVRpeeerwrgaiervlggfalTLLVPPEHYAAalrwvnrlHLRGRLVYERVRTGLPDPERPRld 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1282 ----------RSSALREEVQSL----------------------------------------REEVEKQRVVSENSRQEL 1311
Cdd:COG4913    533 pdslagkldfKPHPFRAWLEAElgrrfdyvcvdspeelrrhpraitragqvkgngtrhekddRRRIRSRYVLGFDNRAKL 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1312 ASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALvsellpakhlcqqlqaeqaaaekrfrEELEQSKQAAGGL 1391
Cdd:COG4913    613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRL--------------------------AEYSWDEIDVASA 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1392 QAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEnrglgeranlgRQFLEVELDQAREK 1471
Cdd:COG4913    667 EREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKE-----------LEQAEEELDELQDR 735

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176315 1472 YVQELAAVRTDAETHLAEMRQEAQSTSRELEVmtakyegakvkvleeRQRFQEERQKLTAQVEELSKKLTE 1542
Cdd:COG4913    736 LEAAEDLARLELRALLEERFAAALGDAVEREL---------------RENLEERIDALRARLNRAEEELER 791
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 653-1676 2.38e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.87  E-value: 2.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  653 IEASHQEQRQVQARVTELEAQLKAEQQKTTErekVVQEKAQLQEQLRALEESLKitkgslEEEKRRAADALKEQQCRATE 732
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQ---LCEEKNALQEQLQAETELCA------EAEEMRARLAARKQELEEIL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  733 MEAESRslMEQREREQKELEQEKagrKGLEARIQQLEEaHQAETEALRHELaeatasqHRAESECERLIREVESRQKRFE 812
Cdd:pfam01576   78 HELESR--LEEEEERSQQLQNEK---KKMQQHIQDLEE-QLDEEEAARQKL-------QLEKVTTEAKIKKLEEDILLLE 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  813 ARQQEEARYGAMFQEQLmalkGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSAL 892
Cdd:pfam01576  145 DQNSKLSKERKLLEERI----SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDL 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  893 QEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASdqlgeqqgrpfssthaAVKAMEREAEQMGGELERLR 972
Cdd:pfam01576  221 QEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALK----------------KIRELEAQISELQEDLESER 284

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  973 AALIKSQgqqqeergqqerevarltqergQAQADLAQE-KAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQ 1051
Cdd:pfam01576  285 AARNKAE----------------------KQRRDLGEElEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRS 342

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1052 ELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGpgtqsetagktdapgpELQALRAEISKLEQQ 1131
Cdd:pfam01576  343 HEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQA----------------ELRTLQQAKQDSEHK 406

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1132 CQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQD-HSKAEEEWKAQVA 1210
Cdd:pfam01576  407 RKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDtQELLQEETRQKLN 486

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1211 ---RGQQEAERKSSLISSLEEEVSI---LNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSS 1284
Cdd:pfam01576  487 lstRLRQLEDERNSLQEQLEEEEEAkrnVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAA 566

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1285 A---LREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQ---ELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP 1358
Cdd:pfam01576  567 AydkLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQmlaEEKAISARYAEERDRAEAEAREKETRALSLARALE 646

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1359 AKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQREL-GELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLK 1437
Cdd:pfam01576  647 EALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALeQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALK 726

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1438 KAH--GLLAEENRGLGERANLGRQF--LEVELDQAREKYVQELAAvRTDAETHLAEMRQ--EAQSTSRELEVMTAKYEGA 1511
Cdd:pfam01576  727 AQFerDLQARDEQGEEKRRQLVKQVreLEAELEDERKQRAQAVAA-KKKLELDLKELEAqiDAANKGREEAVKQLKKLQA 805

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1512 KVKVLE-ERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLN-------------- 1576
Cdd:pfam01576  806 QMKDLQrELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIAsgasgksalqdekr 885

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1577 ELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQqagLKTKEAEQTCR 1656
Cdd:pfam01576  886 RLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELK---AKLQEMEGTVK 962

                         1050      1060
                   ....*....|....*....|.
gi 1907176315 1657 -HLTAQVRSLEAQVAHADQQL 1676
Cdd:pfam01576  963 sKFKSSIAALEAKIAQLEEQL 983
mukB PRK04863
chromosome partition protein MukB;
1404-1681 2.80e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.04  E-value: 2.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1404 ELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLaeeNRGLGERANLGRQFLEVELDQARE---------KYVQ 1474
Cdd:PRK04863   838 ELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSAL---NRLLPRLNLLADETLADRVEEIREqldeaeeakRFVQ 914

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1475 ELAAVRTDAETHLAEMRQEAQstsrELEVMTAKYEGAkvkvlEERQRFQEERQKLTAQV---------EELSKKLTEHDQ 1545
Cdd:PRK04863   915 QHGNALAQLEPIVSVLQSDPE----QFEQLKQDYQQA-----QQTQRDAKQQAFALTEVvqrrahfsyEDAAEMLAKNSD 985

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1546 ASKVQQQKLKAFQAQRgesqqevQRLQTQLNELQAQLSQKEQAaehyklqMEKAKTHYDAKKQQNQKLQEQLQDLEELQK 1625
Cdd:PRK04863   986 LNEKLRQRLEQAEQER-------TRAREQLRQAQAQLAQYNQV-------LASLKSSYDAKRQMLQELKQELQDLGVPAD 1051

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176315 1626 ENKELRSEAERlgRELQQAglkTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1681
Cdd:PRK04863  1052 SGAEERARARR--DELHAR---LSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLER 1102
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1287-1668 4.39e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 52.26  E-value: 4.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1287 REEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKawqekffQKEQALSALQLEHTSTQAlvsellpakHLcqql 1366
Cdd:COG3096    277 ANERRELSERALELRRELFGARRQLAEEQYRLVEMARELE-------ELSARESDLEQDYQAASD---------HL---- 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1367 qaeqaaaekrfreeleQSKQAAGGLQAELMRAQRELGELGS--LRQKIVEQERAAQQLRAEKASYAEQLSmLKKAHGLLA 1444
Cdd:COG3096    337 ----------------NLVQTALRQQEKIERYQEDLEELTErlEEQEEVVEEAAEQLAEAEARLEAAEEE-VDSLKSQLA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1445 EENRGLGE---RANLGRQFLEVeLDQAREkyVQELAAVRTD-AETHLAEMRQEAQSTSRELEVMTAKYEGAKvkvlEERQ 1520
Cdd:COG3096    400 DYQQALDVqqtRAIQYQQAVQA-LEKARA--LCGLPDLTPEnAEDYLAAFRAKEQQATEEVLELEQKLSVAD----AARR 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1521 RFQEERQKLTAQVEElskklTEHDQASKVQQQKLKAFQAQRGESQQEVQrLQTQLNELQAQLSQKEQAAEhyklqmekak 1600
Cdd:COG3096    473 QFEKAYELVCKIAGE-----VERSQAWQTARELLRRYRSQQALAQRLQQ-LRAQLAELEQRLRQQQNAER---------- 536

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315 1601 thydAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQ 1668
Cdd:COG3096    537 ----LLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAAR 600
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
504-898 4.47e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 4.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  504 LNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHaQQLAIVA 583
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREEL-EKLEKLL 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  584 EAREAsLRERDTARQQLETVE------KEKDAKLESLQQQLQAANDARDNAQTSVTQA-QQEKAELSQKIGELHACIEAS 656
Cdd:COG4717    126 QLLPL-YQELEALEAELAELPerleelEERLEELRELEEELEELEAELAELQEELEELlEQLSLATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  657 HQEQRQVQARVTELEAQLKAEQQKTTEREKvVQEKAQLQEQLRALEESLKI---------TKGSLEEEKRRAADALKEQQ 727
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLEN-ELEAAALEERLKEARLLLLIaaallallgLGGSLLSLILTIAGVLFLVL 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  728 CRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAE------------ATASQHRAES 795
Cdd:COG4717    284 GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLElldrieelqellREAEELEEEL 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  796 ECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKtgQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQV 875
Cdd:COG4717    364 QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEEL--EELEEQLEELLGELEELLEALDEEELEEELEELEEEL 441

                          410       420
                   ....*....|....*....|...
gi 1907176315  876 QEKEVRAQKLVDDLSALQEKMAA 898
Cdd:COG4717    442 EELEEELEELREELAELEAELEQ 464
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1514-1692 5.12e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 5.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1514 KVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQ-----KEQA 1588
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAqkeelAELL 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1589 AEHYKL----------------QMEKAKTHYDAKKQQNQKLQEQLQ-DLEELQKENKELRSEAERLGRELQQAGLKTKEA 1651
Cdd:COG4942    111 RALYRLgrqpplalllspedflDAVRRLQYLKYLAPARREQAEELRaDLAELAALRAELEAERAELEALLAELEEERAAL 190

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1907176315 1652 EQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSR 1692
Cdd:COG4942    191 EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1531-1679 5.77e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.31  E-value: 5.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1531 AQVEELSKKLtehdQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKL--QMEKAKTHYDAKKQ 1608
Cdd:COG4717     71 KELKELEEEL----KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqELEALEAELAELPE 146

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176315 1609 QNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTK-EAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1679
Cdd:COG4717    147 RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELEEA 218
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 628-845 5.84e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 5.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  628 AQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREkvvQEKAQLQEQLRALEESLKI 707
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  708 TKGSLEEEKRRAADALKEQQ--------------CRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAhQ 773
Cdd:COG4942     95 LRAELEAQKEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE-R 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176315  774 AETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEA 845
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1140-1679 8.31e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.12  E-value: 8.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1140 EGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARgQQEAERK 1219
Cdd:TIGR00618  197 ELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRAR-IEELRAQ 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1220 SSLISSLEEEVSiLNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEK 1299
Cdd:TIGR00618  276 EAVLEETQERIN-RARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1300 QRVVSENSRQEL-ASQAERAEELGQELKAWQEK---FFQKEQALSALQLEHTSTQALVSEL----------LPAKHLCQQ 1365
Cdd:TIGR00618  355 IHIRDAHEVATSiREISCQQHTLTQHIHTLQQQkttLTQKLQSLCKELDILQREQATIDTRtsafrdlqgqLAHAKKQQE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1366 LQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKAS-YAEQLSMLKKAHGLLA 1444
Cdd:TIGR00618  435 LQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLeLQEEPCPLCGSCIHPN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1445 EENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAET-HLAEMRQEAQSTSRELEVMTAKYEGAKvKVLEERQRFQ 1523
Cdd:TIGR00618  515 PARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERkQRASLKEQMQEIQQSFSILTQCDNRSK-EDIPNLQNIT 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1524 EERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQ------TQLNELQAQLSQKEQAAEHYKLQME 1597
Cdd:TIGR00618  594 VRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELAlkltalHALQLTLTQERVREHALSIRVLPKE 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1598 KAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRelqqaglKTKEAEQTCRHLTAQVRSLEAQVAHADQQLR 1677
Cdd:TIGR00618  674 LLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEE-------YDREFNEIENASSSLGSDLAAREDALNQSLK 746


                   ..
gi 1907176315 1678 DL 1679
Cdd:TIGR00618  747 EL 748
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1474-1724 8.48e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 8.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1474 QELAAVRTDAEtHLAEMRQEAQSTSRELEVMTAKYEGAkvkvLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQK 1553
Cdd:PRK02224   213 SELAELDEEIE-RYEEQREQARETRDEADEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRER 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1554 LKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEElqkENKELRSE 1633
Cdd:PRK02224   288 LEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEE---RAEELREE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1634 AERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEE 1713
Cdd:PRK02224   365 AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE 444

                          250
                   ....*....|.
gi 1907176315 1714 GTPCSVASKLP 1724
Cdd:PRK02224   445 AEALLEAGKCP 455
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
136-717 8.77e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 8.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  136 DHEESLNLTEDLESFLEKVPYTHASTLSE--ELSPPSHQTKRKIRFLEiQRIASSSSENNFLSGSPSSpmgdilqtpqfq 213
Cdd:PRK02224   245 EHEERREELETLEAEIEDLRETIAETEREreELAEEVRDLRERLEELE-EERDDLLAEAGLDDADAEA------------ 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  214 mrrLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLAllnekqaassqepSELEELRGKNESLTVRLHET 293
Cdd:PRK02224   312 ---VEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE-------------ERAEELREEAAELESELEEA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  294 LKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEhskasqewaekqarlENELSTALQDKKC 373
Cdd:PRK02224   376 REAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRER---------------EAELEATLRTARE 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  374 LEEKNEILqgklsqledqatrLQESPAPEKGEVLGDALQLDTL---KQEAAKLATDNTQLQTRVETLE--CERGKQEAQL 448
Cdd:PRK02224   441 RVEEAEAL-------------LEAGKCPECGQPVEGSPHVETIeedRERVEELEAELEDLEEEVEEVEerLERAEDLVEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  449 LAERSRFEDEKQQLASLIADLQssvsnlsqakeeleqasqaqgaqltaqltsmtglnATLQQRDQELASLKEQAKKEQAQ 528
Cdd:PRK02224   508 EDRIERLEERREDLEELIAERR-----------------------------------ETIEEKRERAEELRERAAELEAE 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  529 mlqtMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRqDHAQQLAIVAEAREA--SLRERDTARQQLETVEKE 606
Cdd:PRK02224   553 ----AEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEieRLREKREALAELNDERRE 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  607 KDAKLESLQQQLQAANDArdnaqTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKaEQQKTTEREK 686
Cdd:PRK02224   628 RLAEKRERKRELEAEFDE-----ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELE-ELEELRERRE 701

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1907176315  687 VVQEKAQLQEQLRALEESLKITKGSLEEEKR 717
Cdd:PRK02224   702 ALENRVEALEALYDEAEELESMYGDLRAELR 732
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 521-814 9.06e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.11  E-value: 9.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  521 QAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEA----AKEQEATRQ----DHAQQ--------LAIVAE 584
Cdd:COG3096    289 ELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAAsdhlNLVQTALRQqekiERYQEdleelterLEEQEE 368

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  585 AREASLRERDTARQQLETVEKEKDakleSLQQQLQAANDARDNAQTSVTQAQQEKaelsQKIGELHACIEASHQEQRQVQ 664
Cdd:COG3096    369 VVEEAAEQLAEAEARLEAAEEEVD----SLKSQLADYQQALDVQQTRAIQYQQAV----QALEKARALCGLPDLTPENAE 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  665 ARVTELEAQlkaEQQKTTEREKVVQEKAQLQEQLRALEESLK-ITKGSLEEEKRRAADALKEQQCRATEMEAESRSL--- 740
Cdd:COG3096    441 DYLAAFRAK---EQQATEEVLELEQKLSVADAARRQFEKAYElVCKIAGEVERSQAWQTARELLRRYRSQQALAQRLqql 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  741 ------MEQREREQ-------KELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQhraeSECERLIREVESR 807
Cdd:COG3096    518 raqlaeLEQRLRQQqnaerllEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQR----SELRQQLEQLRAR 593


                   ....*..
gi 1907176315  808 QKRFEAR 814
Cdd:COG3096    594 IKELAAR 600
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 260-907 1.06e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.94  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  260 ALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAF 339
Cdd:pfam01576  447 SLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQL 526

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  340 NDL---IEEHSKASQEWAEKQARLENELSTALQdkkCLEEKNEilqgKLSQLEDQATRLQEspapekgEVLGDALQLDTL 416
Cdd:pfam01576  527 SDMkkkLEEDAGTLEALEEGKKRLQRELEALTQ---QLEEKAA----AYDKLEKTKNRLQQ-------ELDDLLVDLDHQ 592

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  417 KQeaakLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTA 496
Cdd:pfam01576  593 RQ----LVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMED 668

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  497 QLTSMTGLNATLQqrdqELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHA 576
Cdd:pfam01576  669 LVSSKDDVGKNVH----ELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKR 744

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  577 QQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEAS 656
Cdd:pfam01576  745 RQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEI 824

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  657 HQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAAD-------ALKEQQCR 729
Cdd:pfam01576  825 LAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEAriaqleeELEEEQSN 904

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  730 ATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQaETEALRHELAEATASQHRA-----ESECERLIREV 804
Cdd:pfam01576  905 TELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNK-ELKAKLQEMEGTVKSKFKSsiaalEAKIAQLEEQL 983

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  805 ESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEihsegqpgQQQSQLAQLHASLAKAIQQVQEKEVRAQK 884
Cdd:pfam01576  984 EQESRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAE--------KGNSRMKQLKRQLEEAEEEASRANAARRK 1055

                          650       660
                   ....*....|....*....|...
gi 1907176315  885 LVDDLSALQEKMAATNKEVACLK 907
Cdd:pfam01576 1056 LQRELDDATESNESMNREVSTLK 1078
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1189-1321 1.09e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 50.63  E-value: 1.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1189 QALRaKAQDHSKAEEEWKAQVARGQQEAERkssliSSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL 1268
Cdd:COG2433    380 EALE-ELIEKELPEEEPEAEREKEHEEREL-----TEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEA 453

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176315 1269 QVEtASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELasqaERAEEL 1321
Cdd:COG2433    454 RSE-ERREIRKDREISRLDREIERLERELEEERERIEELKRKL----ERLKEL 501
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1153-1669 1.12e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.81  E-value: 1.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1153 RAEQDKALETLQGQLEEK-ARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVS 1231
Cdd:PRK02224   182 LSDQRGSLDQLKAQIEEKeEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1232 ILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSA---RAAERSSALREEVQSLREEVEKQRVVSENSR 1308
Cdd:PRK02224   262 DLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDAdaeAVEARREELEDRDEELRDRLEECRVAAQAHN 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1309 QELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqqlqaeqaaaekrfREELEQSKQAA 1388
Cdd:PRK02224   342 EEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEEL---------------------EEEIEELRERF 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1389 GGLQAELMRAQRELGELGSLRQKIVEQERaaqQLRAEKASYAEQLsmlkkahgllaEENRGLGERANLGRQFLEVE---- 1464
Cdd:PRK02224   401 GDAPVDLGNAEDFLEELREERDELREREA---ELEATLRTARERV-----------EEAEALLEAGKCPECGQPVEgsph 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1465 ---LDQAREKyVQELAAVRTDAETHLAEMRQ------EAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLtaqvEE 1535
Cdd:PRK02224   467 vetIEEDRER-VEELEAELEDLEEEVEEVEErleraeDLVEAEDRIERLEERREDLEELIAERRETIEEKRERA----EE 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1536 LSKKLTEHDQASkvqQQKLKAFQAQRGESQQEVQRLQTqlnelqaqlsqkeqaaehyklqmekakthYDAKKQQNQKLQE 1615
Cdd:PRK02224   542 LRERAAELEAEA---EEKREAAAEAEEEAEEAREEVAE-----------------------------LNSKLAELKERIE 589

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907176315 1616 QLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQV 1669
Cdd:PRK02224   590 SLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEF 643
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1557-1679 1.12e-05

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 49.66  E-value: 1.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1557 FQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEhYKLQMEKAKTHYDAKKQQ---NQKLQEQ----LQDLEELQKENKE 1629
Cdd:COG1566     81 LQAALAQAEAQLAAAEAQLARLEAELGAEAEIAA-AEAQLAAAQAQLDLAQRElerYQALYKKgavsQQELDEARAALDA 159

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1630 LRSEAERLGRELQQAGLKTKEAEQTcRHLTAQVRSLEAQVAHADQQLRDL 1679
Cdd:COG1566    160 AQAQLEAAQAQLAQAQAGLREEEEL-AAAQAQVAQAEAALAQAELNLART 208
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 211-764 1.12e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.94  E-value: 1.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  211 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLA----LLNEKQAASSQEPSELEE-------L 279
Cdd:pfam01576  102 QQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSkerkLLEERISEFTSNLAEEEEkakslskL 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  280 RGKNESLTVRLHETLKQC----QNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQ----LQGAFNDLIEEHSKASQ 351
Cdd:pfam01576  182 KNKHEAMISDLEERLKKEekgrQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKkeeeLQAALARLEEETAQKNN 261

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  352 ----------EWAEKQARLENEL---STALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVlgdALQLDTLKQ 418
Cdd:pfam01576  262 alkkireleaQISELQEDLESERaarNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEV---TELKKALEE 338

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  419 EAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLtaql 498
Cdd:pfam01576  339 ETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQL---- 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  499 tsmtglnatlqqrdQELASLKEQAKKEQaqmlqtmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATrqdhAQQ 578
Cdd:pfam01576  415 --------------QELQARLSESERQR-------AELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSL----ESQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  579 LAIVAEAREASLRERDTARQQLETVEKEKDakleSLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQ 658
Cdd:pfam01576  470 LQDTQELLQEETRQKLNLSTRLRQLEDERN----SLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEE 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  659 EQRQVQarvTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRAL---EESLKITKGSLEEEKRRAADALKEQQ-CRATEME 734
Cdd:pfam01576  546 GKKRLQ---RELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLlvdLDHQRQLVSNLEKKQKKFDQMLAEEKaISARYAE 622

                          570       580       590
                   ....*....|....*....|....*....|
gi 1907176315  735 AESRSLMEQREREQKELEQEKAGRKGLEAR 764
Cdd:pfam01576  623 ERDRAEAEAREKETRALSLARALEEALEAK 652
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 503-619 1.18e-05

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 48.73  E-value: 1.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  503 GLNATLQQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGlRQQVEQLSSSLKLKEQQLEEAAKEQEaTRQDHAQQLAIV 582
Cdd:NF038305    98 HLNNTRRLSTQALQQINQQAGQQETQ-LQQQLNQLQAQTS-PQQLNQLLKSEQKQGQALASGQLPEE-QKEQLQQFKSNP 174

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1907176315  583 AEAREASLRERDTARQQLETVEKEkdAKLESLQQQLQ 619
Cdd:NF038305   175 QALDKFLAQQLTQIRTQAEEAEKQ--ARLEALKSSLR 209
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 685-1474 1.47e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.50  E-value: 1.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  685 EKVVQEKAQlqeQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEkagRKGLEAR 764
Cdd:pfam15921   77 ERVLEEYSH---QVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDL---RNQLQNT 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  765 IQQLEEAHQAETEALRHELAEATASQHRAESEcERLIREVESRQKRFEarqqEEARYGAMFQEQLMALKGEKTGQEVQEE 844
Cdd:pfam15921  151 VHELEAAKCLKEDMLEDSNTQIEQLRKMMLSH-EGVLQEIRSILVDFE----EASGKKIYEHDSMSTMHFRSLGSAISKI 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  845 AVEIHSE-----GQPGQQQSQLAQLHASLAKAIQQV-QEKEVRAQKLVDD----LSALQEKMAATNKEVACLKTlvlkag 914
Cdd:pfam15921  226 LRELDTEisylkGRIFPVEDQLEALKSESQNKIELLlQQHQDRIEQLISEheveITGLTEKASSARSQANSIQS------ 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  915 eqqetaSLELLKEPPRAANrasdQLGEQQGRPFSSTHAAVKAMEREAEQM-GGELERLRAALIKSQgqqqeergqqerev 993
Cdd:pfam15921  300 ------QLEIIQEQARNQN----SMYMRQLSDLESTVSQLRSELREAKRMyEDKIEELEKQLVLAN-------------- 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  994 ARLTQERGQaQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQT 1073
Cdd:pfam15921  356 SELTEARTE-RDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEAL 434

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1074 LEQLKIQlVKKEKEHPAGGASGEDASGPGTQSETAgKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACR 1153
Cdd:pfam15921  435 LKAMKSE-CQGQMERQMAAIQGKNESLEKVSSLTA-QLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAI 512

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1154 AEQDKALETLQGQLEEKARELGHNQAAS---ASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEV 1230
Cdd:pfam15921  513 EATNAEITKLRSRVDLKLQELQHLKNEGdhlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEK 592

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1231 SILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREevqsLREEVEKQRVVSENSRQE 1310
Cdd:pfam15921  593 AQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKD----IKQERDQLLNEVKTSRNE 668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1311 LASQAERAEELGQELKAWQEKFfqkEQALSALQLEHTSTQalvSELlpakhlcqqlqAEQAAAEKRFREELEQSKQAAGG 1390
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEM---ETTTNKLKMQLKSAQ---SEL-----------EQTRNTLKSMEGSDGHAMKVAMG 731

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1391 LQAELMrAQRelGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLA-EENRGLGERANLGRQ---------F 1460
Cdd:pfam15921  732 MQKQIT-AKR--GQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVAtEKNKMAGELEVLRSQerrlkekvaN 808

                          810
                   ....*....|....
gi 1907176315 1461 LEVELDQAREKYVQ 1474
Cdd:pfam15921  809 MEVALDKASLQFAE 822
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
385-803 1.51e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 1.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  385 LSQLEDQATRLQESPApEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLE---------CERGKQEAQLLAERSRF 455
Cdd:COG4717     70 LKELKELEEELKEAEE-KEEEYAELQEELEELEEELEELEAELEELREELEKLEkllqllplyQELEALEAELAELPERL 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  456 EDEKQQLASlIADLQSSVSNLSQAKEELEQASQAQGAQLT-AQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQ 534
Cdd:COG4717    149 EELEERLEE-LRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  535 -----EQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDA 609
Cdd:COG4717    228 eleqlENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  610 KLESLQQQLQAA--NDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKV 687
Cdd:COG4717    308 QALPALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEEL 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  688 VQeKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQcrATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQ 767
Cdd:COG4717    388 RA-ALEQAEEYQELKEELEELEEQLEELLGELEELLEALD--EEELEEELEELEEELEELEEELEELREELAELEAELEQ 464

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1907176315  768 LEEAhqaetealrHELAEATASQHRAESECERLIRE 803
Cdd:COG4717    465 LEED---------GELAELLQELEELKAELRELAEE 491
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 412-816 1.51e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 50.18  E-value: 1.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASL---------IADLQSSVSNLSQAKEE 482
Cdd:PRK10246   427 RLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVkticeqearIKDLEAQRAQLQAGQPC 506

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  483 LEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQ---MLQTMQEQEQAAQGLRQQVEQLSS------- 552
Cdd:PRK10246   507 PLCGSTSHPAVEAYQALEPGVNQSRLDALEKEVKKLGEEGAALRGQldaLTKQLQRDESEAQSLRQEEQALTQqwqavca 586

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  553 SLKLKEQQLEEAAKEQEAtRQDHAQQLAIVAEARE------ASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND--- 623
Cdd:PRK10246   587 SLNITLQPQDDIQPWLDA-QEEHERQLRLLSQRHElqgqiaAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEeas 665

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  624 ---ARDNAQTSVTQAQQEKAELSQKIGELHACIE--------------ASHQEQRQVQARVTELEAQLKAEQQKTTerek 686
Cdd:PRK10246   666 wlaTRQQEAQSWQQRQNELTALQNRIQQLTPLLEtlpqsddlphseetVALDNWRQVHEQCLSLHSQLQTLQQQDV---- 741

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  687 vvQEKAQLQEQLRALEESLkitKGSLEEEKRRAADALkeqqcrateMEAESRSLMEQRereQKELEQEKAGRKGLEARIQ 766
Cdd:PRK10246   742 --LEAQRLQKAQAQFDTAL---QASVFDDQQAFLAAL---------LDEETLTQLEQL---KQNLENQRQQAQTLVTQTA 804

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176315  767 QLEEAHQAETEALRHELAEATASQHRAESECERLiREVESRQKrfEARQQ 816
Cdd:PRK10246   805 QALAQHQQHRPDGLDLTVTVEQIQQELAQLAQQL-RENTTRQG--EIRQQ 851
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 856-1087 1.55e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  856 QQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEvaclktlvLKAGEQQETASLELLKEPPRAANRA 935
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR--------IRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  936 SDQLGEQQgrpfssthAAVKAMEREAEQMGgeleRLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKA 1015
Cdd:COG4942     96 RAELEAQK--------EELAELLRALYRLG----RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176315 1016 ELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKE 1087
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1519-1690 1.59e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.02  E-value: 1.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1519 RQRFQEERQKLTAQVEELSKKLTEHDQaskvqQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEK 1598
Cdd:COG3206    177 LEFLEEQLPELRKELEEAEAALEEFRQ-----KNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGS 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1599 AKTH---------YDAKKQQNQKLQEQLQDLEELQKEN----KELRSEAERLGRELQQAGLKTK-EAEQTCRHLTAQVRS 1664
Cdd:COG3206    252 GPDAlpellqspvIQQLRAQLAELEAELAELSARYTPNhpdvIALRAQIAALRAQLQQEAQRILaSLEAELEALQAREAS 331

                          170       180
                   ....*....|....*....|....*.
gi 1907176315 1665 LEAQVAHADQQLRDLGKFQVATDALK 1690
Cdd:COG3206    332 LQAQLAQLEARLAELPELEAELRRLE 357
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1158-1349 1.69e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1158 KALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQ--VARGQQEAERKSSLISSLEE---EVSI 1232
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidVASAEREIAELEAELERLDAssdDLAA 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1233 LNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEvqsLREEVEKQRvvsensRQELA 1312
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLE---LRALLEERF------AAALG 760

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1907176315 1313 SQAER--AEELGQELKAWQEKFFQKEQALSALQLEHTST 1349
Cdd:COG4913    761 DAVERelRENLEERIDALRARLNRAEEELERAMRAFNRE 799
PRK12704 PRK12704
phosphodiesterase; Provisional
 558-756 1.74e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 49.78  E-value: 1.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  558 EQQLEEAAKEQEATRQDhaqqlaIVAEAREaslrERDTARQQLETVEKEKDAKLESLQQQLqaandardnaqtsvtqaQQ 637
Cdd:PRK12704    41 KRILEEAKKEAEAIKKE------ALLEAKE----EIHKLRNEFEKELRERRNELQKLEKRL-----------------LQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  638 EKAELSQKIGELhacieashqEQRqvQARVTELEAQLKAEQQKTTEREKVVQEKaqLQEQLRALEESLKITKgslEEEKR 717
Cdd:PRK12704    94 KEENLDRKLELL---------EKR--EEELEKKEKELEQKQQELEKKEEELEEL--IEEQLQELERISGLTA---EEAKE 157

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1907176315  718 RAADALKEqqcratEMEAESRSLMEQREREQKELEQEKA 756
Cdd:PRK12704   158 ILLEKVEE------EARHEAAVLIKEIEEEAKEEADKKA 190
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1008-1679 1.78e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1008 AQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTD-----QELAKLRGQEAAQRTELKELQQTLEQLKIQLV 1082
Cdd:COG4913    240 AHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRlwfaqRRLELLEAELEELRAELARLEAELERLEARLD 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1083 KKEKEHpaggasgedasgpgtQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQveglthslkseracRAEQDKALET 1162
Cdd:COG4913    320 ALREEL---------------DELEAQIRGNGGDRLEQLEREIERLERELEERERR--------------RARLEALLAA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1163 LQGQLEEKARELGHNQAASASAQRELQALRAKAQDhskAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLekeg 1242
Cdd:COG4913    371 LGLPLPASAEEFAALRAEAAALLEALEEELEALEE---ALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLL---- 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1243 eskELKRLVVAESEKSqklEERLR----LLQVETASNSAR-AAERssALREEVQSL--REEVEKQrvvsensrqelASQA 1315
Cdd:COG4913    444 ---ALRDALAEALGLD---EAELPfvgeLIEVRPEEERWRgAIER--VLGGFALTLlvPPEHYAA-----------ALRW 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1316 ERAEELGQELkawqeKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFR--EELEQSKQAAGGLQA 1393
Cdd:COG4913    505 VNRLHLRGRL-----VYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRFDYVcvDSPEELRRHPRAITR 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1394 E-LMRAQRELGELG-------------SLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLgrQ 1459
Cdd:COG4913    580 AgQVKGNGTRHEKDdrrrirsryvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEY--S 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1460 FLEVELDQAREKYV---QELAAVRTDAEThLAEMRQEAQSTSRELEVMTAKYEGAKvkvlEERQRFQEERQKLTAQVEEL 1536
Cdd:COG4913    658 WDEIDVASAEREIAeleAELERLDASSDD-LAALEEQLEELEAELEELEEELDELK----GEIGRLEKELEQAEEELDEL 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1537 SKKLTEHDQASKVQQQKL--KAFQAQRGE--SQQEVQRLQTQLNELQAQLSQKEQAAEhykLQMEKAKTHYDAKKQQnqk 1612
Cdd:COG4913    733 QDRLEAAEDLARLELRALleERFAAALGDavERELRENLEERIDALRARLNRAEEELE---RAMRAFNREWPAETAD--- 806

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176315 1613 LQEQLQDLEELQKENKELrsEAERLGRELQQagLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1679
Cdd:COG4913    807 LDADLESLPEYLALLDRL--EEDGLPEYEER--FKELLNENSIEFVADLLSKLRRAIREIKERIDPL 869
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1033-1666 1.85e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.97  E-value: 1.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1033 AALQEALAHALTEKEGTDQELAKLRgqeaaQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAgktd 1112
Cdd:TIGR00618  222 QVLEKELKHLREALQQTQQSHAYLT-----QKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKA---- 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1113 APGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAasasaQRELQALR 1192
Cdd:TIGR00618  293 APLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRD-----AHEVATSI 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1193 AKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVET 1272
Cdd:TIGR00618  368 REISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAI 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1273 ASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQAL 1352
Cdd:TIGR00618  448 TCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARL-LELQEEPCPLCGSCIHPNPARQDIDNPGPL 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1353 VSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQaaggLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQ 1432
Cdd:TIGR00618  527 TRRMQRGEQTYAQLETSEEDVYHQLTSERKQRAS----LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEK 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1433 LSMLKKAhglLAEENRGLGERAN--LGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEG 1510
Cdd:TIGR00618  603 LSEAEDM---LACEQHALLRKLQpeQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQ 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1511 AKVKVLEERQRF-----------QEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQ-TQLNEL 1578
Cdd:TIGR00618  680 LALQKMQSEKEQltywkemlaqcQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQArTVLKAR 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1579 ---QAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLE-----ELQKENKELRSEAERLGRELQQAGLKTKE 1650
Cdd:TIGR00618  760 teaHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEaeigqEIPSDEDILNLQCETLVQEEEQFLSRLEE 839

                          650
                   ....*....|....*.
gi 1907176315 1651 AEQTCRHLTAQVRSLE 1666
Cdd:TIGR00618  840 KSATLGEITHQLLKYE 855
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 412-640 2.19e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLlaerSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 491
Cdd:COG4942     28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI----AALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  492 AQLTAQLTSMtglnATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 571
Cdd:COG4942    104 EELAELLRAL----YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315  572 RQDHAQQLAIVAEAREaslrERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKA 640
Cdd:COG4942    180 LAELEEERAALEALKA----ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
630-796 2.31e-05

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 49.10  E-value: 2.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  630 TSVTQAQQEKAELSQKIGELHacIEASHQEQRQVQA-RVTELEAQLKAEQQKttEREKVVQEKAQLQEQLRAL-EESLKI 707
Cdd:COG2268    195 AEIIRDARIAEAEAERETEIA--IAQANREAEEAELeQEREIETARIAEAEA--ELAKKKAEERREAETARAEaEAAYEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  708 TkgslEEEKRRAADALKEQQCRATEMEAEsrslmeQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHE-LAEA 786
Cdd:COG2268    271 A----EANAEREVQRQLEIAEREREIELQ------EKEAEREEAELEADVRKPAEAEKQAAEAEAEAEAEAIRAKgLAEA 340

                          170
                   ....*....|
gi 1907176315  787 TASQHRAESE 796
Cdd:COG2268    341 EGKRALAEAW 350
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 354-570 2.33e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  354 AEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTR 433
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  434 VETLECERGKQ--EAQLLAERSRFE-----DEKQQLASLIADLQSSVSNLSQAKEELEQASQ---AQGAQLTAQLTSMTG 503
Cdd:COG4942     99 LEAQKEELAELlrALYRLGRQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAelaALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176315  504 LNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEA 570
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 572-1425 2.45e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.57  E-value: 2.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  572 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLES---LQQQLQAANDARDNAQTSVtqAQQEKAElsqkige 648
Cdd:COG3096    280 RRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSAResdLEQDYQAASDHLNLVQTAL--RQQEKIE------- 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  649 lhacieashqeqrQVQARVTELEAQLKAEQQKTTEREkvvQEKAQLQEQLRALEESLKITKGSLEEEKRraadALKEQQC 728
Cdd:COG3096    351 -------------RYQEDLEELTERLEEQEEVVEEAA---EQLAEAEARLEAAEEEVDSLKSQLADYQQ----ALDVQQT 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  729 RATEMEAESRSLmeqrEREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRH-----ELAEATASQHRAESE-CERLIR 802
Cdd:COG3096    411 RAIQYQQAVQAL----EKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLEleqklSVADAARRQFEKAYElVCKIAG 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  803 EVESRQKRFEARQQ-EEARYGAMFQEQLMALKgektgQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVR 881
Cdd:COG3096    487 EVERSQAWQTARELlRRYRSQQALAQRLQQLR-----AQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAE 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  882 AQKLVDDLSALQEkmAATNKEVACLKTLVLKAGEQQETASlellKEPP-RAANRASDQLGEQQGRPFSSTHAAVKAMERE 960
Cdd:COG3096    562 LEAQLEELEEQAA--EAVEQRSELRQQLEQLRARIKELAA----RAPAwLAAQDALERLREQSGEALADSQEVTAAMQQL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  961 aeqmggeLERLRAALIkSQGQQQEERGQQEREVARLTQERGQAQADLAQekaakaeLEMRLQNTLNEQRVEFAALQEA-- 1038
Cdd:COG3096    636 -------LEREREATV-ERDELAARKQALESQIERLSQPGGAEDPRLLA-------LAERLGGVLLSEIYDDVTLEDApy 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1039 -------LAHAL---------------------------------------TEKEGTDqeLAKLRGQE------------ 1060
Cdd:COG3096    701 fsalygpARHAIvvpdlsavkeqlagledcpedlyliegdpdsfddsvfdaEELEDAV--VVKLSDRQwrysrfpevplf 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1061 ---------AAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASgedasgPGTQSETAGKTDaPGPELQALRAEISKLEQQ 1131
Cdd:COG3096    779 graarekrlEELRAERDELAEQYAKASFDVQKLQRLHQAFSQF------VGGHLAVAFAPD-PEAELAALRQRRSELERE 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1132 cqqqqqqveglthsLKSERACRAEQDKALETLQGQLEEKARELGHnqaASASAQRELQALRAKAQDHSKAEEEWKAQVAR 1211
Cdd:COG3096    852 --------------LAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQ---ANLLADETLADRLEELREELDAAQEAQAFIQQ 914

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1212 GQQEAERksslissLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQ 1291
Cdd:COG3096    915 HGKALAQ-------LEPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGENSDLNE 987

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1292 SLREEVEkqrvvsensrqelasQAERA-EELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP-----AKHLCQQ 1365
Cdd:COG3096    988 KLRARLE---------------QAEEArREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQeleelGVQADAE 1052

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1366 LQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRelgELGSLRQKIVEQERAAQQLRAE 1425
Cdd:COG3096   1053 AEERARIRRDELHEELSQNRSRRSQLEKQLTRCEA---EMDSLQKRLRKAERDYKQEREQ 1109
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 313-649 2.51e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.58  E-value: 2.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  313 QLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQA 392
Cdd:TIGR00618  539 QLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALL 618

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  393 TRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQ------------ 460
Cdd:TIGR00618  619 RKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQsekeqltywkem 698

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  461 --QLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQltsmtglNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQ 538
Cdd:TIGR00618  699 laQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAR-------EDALNQSLKELMHQARTVLKARTEAHFNNNEEVT 771

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  539 AAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQL 618
Cdd:TIGR00618  772 AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQL 851

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1907176315  619 QAANDARDNAQtsvtQAQQEKAELSQKIGEL 649
Cdd:TIGR00618  852 LKYEECSKQLA----QLTQEQAKIIQLSDKL 878
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1117-1653 2.53e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 2.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1197 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERL---RLLQVETA 1273
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKeeeLELKSEEE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1274 SNSARAAERSSALREEVQSL-----------REEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSAL 1342
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEkkeeleileeeEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1343 QLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQ---------RELGELGSLRQKIV 1413
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYkvaistaviVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1414 EQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRG-LGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQ 1492
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDpILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAK 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1493 EAQS-TSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSK-KLTEHDQASKVQQQKLKAFQAQRGESQQEVQR 1570
Cdd:pfam02463  645 ESGLrKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKeEILRRQLEIKKKEQREKEELKKLKLEAEELLA 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1571 LQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKE 1650
Cdd:pfam02463  725 DRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804


                   ...
gi 1907176315 1651 AEQ 1653
Cdd:pfam02463  805 ALE 807
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 319-699 3.55e-05

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 48.90  E-value: 3.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  319 GDLSFKVREFANHLQQLQGAFNDLIEEHS-KASQEWAEKQARLENELSTAlqDKKCLEEKNEILQGKLSQLEDQATRLQ- 396
Cdd:pfam13166   88 GEESIEIQEKIAKLKKEIKDHEEKLDAAEaNLQKLDKEKEKLEADFLDEC--WKKIKRKKNSALSEALNGFKYEANFKSr 165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  397 -----ESPAPEKGEVLGDAlqldtlkQEAAKLATDNTQLQTRVETLECerGKQEAQLLAERSRFEDEKQQLASLIADLQS 471
Cdd:pfam13166  166 llreiEKDNFNAGVLLSDE-------DRKAALATVFSDNKPEIAPLTF--NVIDFDALEKAEILIQKVIGKSSAIEELIK 236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  472 SVSNLSQAKEELEQASQAQG----------AQLTAQLTSMTGLNATLQQRD-QELASLKEQAKKEQAQMLQTMQEQEQAA 540
Cdd:pfam13166  237 NPDLADWVEQGLELHKAHLDtcpfcgqplpAERKAALEAHFDDEFTEFQNRlQKLIEKVESAISSLLAQLPAVSDLASLL 316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  541 QGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIvaeareaslrerdtarqqletveKEKDAKLESLQQQLQA 620
Cdd:pfam13166  317 SAFELDVEDIESEAEVLNSQLDGLRRALEAKRKDPFKSIEL-----------------------DSVDAKIESINDLVAS 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  621 AND--ARDNAQTSVTQAQQEKAELS---QKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQ 695
Cdd:pfam13166  374 INEliAKHNEITDNFEEEKNKAKKKlrlHLVEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEA---EIKKLREEIKELE 450


                   ....
gi 1907176315  696 EQLR 699
Cdd:pfam13166  451 AQLR 454
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 511-834 4.16e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.18  E-value: 4.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  511 RDQELASLKEQAKKEQAQMLQT---MQEQEQAAQGLRQQV------------EQLSSSLKLKEQQLEEAAKEQEATRQDH 575
Cdd:COG3096    783 REKRLEELRAERDELAEQYAKAsfdVQKLQRLHQAFSQFVgghlavafapdpEAELAALRQRRSELERELAQHRAQEQQL 862

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  576 AQQLaivaeareaslrerDTARQQLETVEK-EKDAKL---ESLQQQLQAANDARDNAQtsvtQAQQEKAELSQKIGELH- 650
Cdd:COG3096    863 RQQL--------------DQLKEQLQLLNKlLPQANLladETLADRLEELREELDAAQ----EAQAFIQQHGKALAQLEp 924

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  651 --ACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQ--------EKAQLQEQLRALEESLKITKGSLEEEKRRAA 720
Cdd:COG3096    925 lvAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQrrphfsyeDAVGLLGENSDLNEKLRARLEQAEEARREAR 1004

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  721 DALKEQQCRATEMEAESRSLMEQREREQKELeqekagrKGLEARIQQLEEAHQAETEAL----RHELAEAtASQHRA--- 793
Cdd:COG3096   1005 EQLRQAQAQYSQYNQVLASLKSSRDAKQQTL-------QELEQELEELGVQADAEAEERarirRDELHEE-LSQNRSrrs 1076

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 1907176315  794 ESECERLIREVESRQKRFEARQQEEaRYGAMFQEQLMALKG 834
Cdd:COG3096   1077 QLEKQLTRCEAEMDSLQKRLRKAER-DYKQEREQVVQAKAG 1116
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 244-923 4.33e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.96  E-value: 4.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  244 EKDAQIAMMQQRIDHLALLNEKQAASSQEPseleelrgkneslTVRLHETLKQCQNLKTEKSQMDRKISQLSEengDLSF 323
Cdd:pfam15921   82 EYSHQVKDLQRRLNESNELHEKQKFYLRQS-------------VIDLQTKLQEMQMERDAMADIRRRESQSQE---DLRN 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  324 KVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLE---NELSTALQDKKCLEEKNEILQGKLSQLEDQAT------- 393
Cdd:pfam15921  146 QLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLgsaiski 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  394 --RLQESPAPEKGEVLGDALQLDTLKQEAaklatdntqlQTRVETLECERGKQEAQLLAERsrfEDEKQQLASLIADLQS 471
Cdd:pfam15921  226 lrELDTEISYLKGRIFPVEDQLEALKSES----------QNKIELLLQQHQDRIEQLISEH---EVEITGLTEKASSARS 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  472 SVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQE--------LASLKEQAKKEQAQMLQTMQEQEQAAQ-- 541
Cdd:pfam15921  293 QANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREakrmyedkIEELEKQLVLANSELTEARTERDQFSQes 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  542 -GLRQQVEQLSSSLKLKEQQLeEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLE----TVEKEKDAKLESLQQ 616
Cdd:pfam15921  373 gNLDDQLQKLLADLHKREKEL-SLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEallkAMKSECQGQMERQMA 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  617 QLQAANDARDNAQTSVTQAQQEKAELSQKIGELHA---CIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQ 693
Cdd:pfam15921  452 AIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAkkmTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  694 LQEQLRALEESLKITKGSLE------EEKRRAADALKEQQCRATE-----------MEAESRSLMEQREREQKELEQEKA 756
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEalklqmAEKDKVIEILRQQIENMTQlvgqhgrtagaMQVEKAQLEKEINDRRLELQEFKI 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  757 GRKGLEARIQQLeEAHQAETEALRHELAEATASQHRA----ESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMAL 832
Cdd:pfam15921  612 LKDKKDAKIREL-EARVSDLELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEM 690

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  833 KGEKTGQEVQEEAVEIHSEgqpgQQQSQLAQLHASLAKAI-------QQVQEKEVRAQKLVDDLSALQEKMAATNKEVAC 905
Cdd:pfam15921  691 ETTTNKLKMQLKSAQSELE----QTRNTLKSMEGSDGHAMkvamgmqKQITAKRGQIDALQSKIQFLEEAMTNANKEKHF 766

                          730
                   ....*....|....*...
gi 1907176315  906 LKTLVLKAGEQQETASLE 923
Cdd:pfam15921  767 LKEEKNKLSQELSTVATE 784
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1485-1679 4.36e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 4.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1485 THLAEMRQEAQSTSRELEVMTakyegakvKVLEERQRFQEERQKLTAQVEELSKkltehdQASKVQQQKLKAFQAQRGES 1564
Cdd:COG4913    235 DDLERAHEALEDAREQIELLE--------PIRELAERYAAARERLAELEYLRAA------LRLWFAQRRLELLEAELEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1565 QQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKThydakkqqnQKLQEQLQDLEELQKENKELRSEAERLGRELQQA 1644
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQIRGNGG---------DRLEQLEREIERLERELEERERRRARLEALLAAL 371

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1907176315 1645 GLKTKEAEQ----TCRHLTAQVRSLEAQVAHADQQLRDL 1679
Cdd:COG4913    372 GLPLPASAEefaaLRAEAAALLEALEEELEALEEALAEA 410
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 577-954 4.47e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.06  E-value: 4.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  577 QQLAIVAEAREASLRERDTARQQ-LETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGElhaciea 655
Cdd:NF012221  1503 KTLKLTAKAGSNRLEFKGTGHNDgLGYILDNVVATSESSQQADAVSKHAKQDDAAQNALADKERAEADRQRLE------- 1575

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  656 shQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGsleeekrraADALKEQQCRATEMEA 735
Cdd:NF012221  1576 --QEKQQQLAAISGSQSQLESTDQNALETNGQAQRDAILEESRAVTKELTTLAQG---------LDALDSQATYAGESGD 1644

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  736 ESRSLMEQR--EREQKELEQEKagrKGLEARIQQLEEAHQAETEALRHELAEATASQHRAesecERLIREVESRQKrfEA 813
Cdd:NF012221  1645 QWRNPFAGGllDRVQEQLDDAK---KISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQG----EQNQANAEQDID--DA 1715

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  814 RQQEEARYGAMFQEQLMALKGEKTGQEVQEEAveihseGQPGQQQSQLAQLHASLAKAiqqvqekevraqklvDDLSALQ 893
Cdd:NF012221  1716 KADAEKRKDDALAKQNEAQQAESDANAAANDA------QSRGEQDASAAENKANQAQA---------------DAKGAKQ 1774

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176315  894 EKMAATNKEVACLKTLVLKAGEQQETA--SLELLKEPPRAAN-RASDQLGEQQGRPFSSTHAAV 954
Cdd:NF012221  1775 DESDKPNRQGAAGSGLSGKAYSVEGVAepGSHINPDSPAAADgRFSEGLTEQEQEALEGATNAV 1838
mukB PRK04863
chromosome partition protein MukB;
1444-1700 4.87e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.80  E-value: 4.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1444 AEENRGLGERANLGRQflevELDQAREKyvqelaavRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAK--VKVLEERQR 1521
Cdd:PRK04863   278 ANERRVHLEEALELRR----ELYTSRRQ--------LAAEQYRLVEMARELAELNEAESDLEQDYQAASdhLNLVQTALR 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1522 FQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAehykLQMEKAKT 1601
Cdd:PRK04863   346 QQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRA----IQYQQAVQ 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1602 HYDAKKQQNQK---LQEQLQD-LEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAH--ADQQ 1675
Cdd:PRK04863   422 ALERAKQLCGLpdlTADNAEDwLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWdvAREL 501

                          250       260
                   ....*....|....*....|....*
gi 1907176315 1676 LRDLGKFQvatdALKSREPQVKPQL 1700
Cdd:PRK04863   502 LRRLREQR----HLAEQLQQLRMRL 522
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 608-790 4.98e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.90  E-value: 4.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  608 DAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKV 687
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  688 VQEK--------------------------AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLM 741
Cdd:COG3883     95 LYRSggsvsyldvllgsesfsdfldrlsalSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1907176315  742 EQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQ 790
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
374-551 5.88e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 5.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  374 LEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNT--QLQTRVETLECERGKQEAQLLAE 451
Cdd:COG3206    210 LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPViqQLRAQLAELEAELAELSARYTPN 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  452 RSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQ 531
Cdd:COG3206    290 HPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES 369

                          170       180
                   ....*....|....*....|
gi 1907176315  532 TMQEQEQAAQGLRQQVEQLS 551
Cdd:COG3206    370 LLQRLEEARLAEALTVGNVR 389
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 941-1653 6.42e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.43  E-value: 6.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  941 EQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLA--QEKAAKAELE 1018
Cdd:TIGR00618  176 DQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAylTQKREAQEEQ 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1019 MRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTEL--KELQQTLEQLKIQLVKKEKEHPAGGASGE 1096
Cdd:TIGR00618  256 LKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQieQQAQRIHTELQSKMRSRAKLLMKRAAHVK 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1097 DASGPGTQSETagktdapgpeLQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQ-----DKALETLQGQLEEKA 1171
Cdd:TIGR00618  336 QQSSIEEQRRL----------LQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQqqkttLTQKLQSLCKELDIL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1172 RELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVargQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLV 1251
Cdd:TIGR00618  406 QREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELC---AAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIH 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1252 VAESEKSQKLEERLRLLQVETA---------SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELG 1322
Cdd:TIGR00618  483 LQETRKKAVVLARLLELQEEPCplcgscihpNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLK 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1323 QELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPakhlcqqlqaeqaaaekRFREELEQSKQAAGGLQAELMRAQREL 1402
Cdd:TIGR00618  563 EQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQD-----------------LTEKLSEAEDMLACEQHALLRKLQPEQ 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1403 GELgSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAeeNRGLGERANLGRQFLEVELdQAREKYVQELAAVRTD 1482
Cdd:TIGR00618  626 DLQ-DVRLHLQQCSQELALKLTALHALQLTLTQERVREHALS--IRVLPKELLASRQLALQKM-QSEKEQLTYWKEMLAQ 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1483 AETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRG 1562
Cdd:TIGR00618  702 CQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELS 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1563 ESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQnqKLQEQLQDLEELQKENKELRSEAERLGRELQ 1642
Cdd:TIGR00618  782 HLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQ--EEEQFLSRLEEKSATLGEITHQLLKYEECSK 859

                          730
                   ....*....|.
gi 1907176315 1643 QAGLKTKEAEQ 1653
Cdd:TIGR00618  860 QLAQLTQEQAK 870
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1149-1678 7.08e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 7.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1149 ERACRAEQD-KALETLQGQLEEKARELGHNQAASASAQRELQALRAK-AQDHSKAEEEWKAQVARGQQEAERKSSLISS- 1225
Cdd:pfam01576   19 ERQQKAESElKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARlAARKQELEEILHELESRLEEEEERSQQLQNEk 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1226 --LEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVV 1303
Cdd:pfam01576   99 kkMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSL 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1304 SENSRQELASQAERAEELGQELKAWQEKffqkEQALSALQLEHTSTQALVSELlpakhlcqqlqaeqaaaEKRFREELEQ 1383
Cdd:pfam01576  179 SKLKNKHEAMISDLEERLKKEEKGRQEL----EKAKRKLEGESTDLQEQIAEL-----------------QAQIAELRAQ 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1384 SKQAAGGLQAELMRAQRELGELGSLRQKIVEqeraaqqLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEV 1463
Cdd:pfam01576  238 LAKKEEELQAALARLEEETAQKNNALKKIRE-------LEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELED 310

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1464 ELD------QAREKYVQELAAVR-------TDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLT 1530
Cdd:pfam01576  311 TLDttaaqqELRSKREQEVTELKkaleeetRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQ 390

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1531 AQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN 1610
Cdd:pfam01576  391 AELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQL 470

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176315 1611 QKLQEQLQDlEELQKENKELR---SEAERLGRELQQaglktKEAEQTCRHLTAQVRSLEAQVAHADQQLRD 1678
Cdd:pfam01576  471 QDTQELLQE-ETRQKLNLSTRlrqLEDERNSLQEQL-----EEEEEAKRNVERQLSTLQAQLSDMKKKLEE 535
PRK11281 PRK11281
mechanosensitive channel MscK;
341-581 7.86e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.98  E-value: 7.86e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  341 DLIEEHSKASQEWAEKQARLENELSTaLQDKKCLEEKNEILQ-------GKLSQLEDQATRLQESPAPEKGEVLgDALQL 413
Cdd:PRK11281    46 DALNKQKLLEAEDKLVQQDLEQTLAL-LDKIDRQKEETEQLKqqlaqapAKLRQAQAELEALKDDNDEETRETL-STLSL 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  414 DTLKQeaaKLATDNTQLQTRVETLecerGKQEAQLLAERSRFE----------DEKQQLASLIADLQSSVSNLS---QAK 480
Cdd:PRK11281   124 RQLES---RLAQTLDQLQNAQNDL----AEYNSQLVSLQTQPEraqaalyansQRLQQIRNLLKGGKVGGKALRpsqRVL 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  481 EELEQAS-QAQGAQLTAQLTSMTGLNATLQQRdQELASLKEQakkEQAQMLQTMQEqeqAAQGLRqqveqlsssLKLKEQ 559
Cdd:PRK11281   197 LQAEQALlNAQNDLQRKSLEGNTQLQDLLQKQ-RDYLTARIQ---RLEHQLQLLQE---AINSKR---------LTLSEK 260

                          250       260
                   ....*....|....*....|....*.
gi 1907176315  560 QLEEAAKEQEATRQDH----AQQLAI 581
Cdd:PRK11281   261 TVQEAQSQDEAARIQAnplvAQELEI 286
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 655-904 7.92e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 7.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  655 ASHQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQEQLRALEESLKitkgsleeekrRAADALKEQQCRATEME 734
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEK---ELAALKKEEKALLKQLAALERRIA-----------ALARRIRALEQELAALE 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  735 AESRSLMEQREREQKELEQEkagRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESEcERLIREVESRQKRFEAR 814
Cdd:COG4942     83 AELAELEKEIAELRAELEAQ---KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL-KYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  815 QQEEARYGAMFQEQLMALKGEKTGQEVQEEAVeihsEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQE 894
Cdd:COG4942    159 LAELAALRAELEAERAELEALLAELEEERAAL----EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234

                          250
                   ....*....|
gi 1907176315  895 KMAATNKEVA 904
Cdd:COG4942    235 EAAAAAERTP 244
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 469-736 8.28e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 48.13  E-value: 8.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  469 LQSSVSNLSQAKEELEqasQAQGAQLTAQLTSMTGLNATLQQRDQELASLkEQAKKEQaqmlQTMQEQEQAAQGLRQQVE 548
Cdd:PRK10929    18 YAATAPDEKQITQELE---QAKAAKTPAQAEIVEALQSALNWLEERKGSL-ERAKQYQ----QVIDNFPKLSAELRQQLN 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  549 QLSSSLKLKEQQLEEAAKEQEaTRQDHAQQLaivAEAREASlRERDTARQ------QLETVEKEKDAKLESLQQQLQAAN 622
Cdd:PRK10929    90 NERDEPRSVPPNMSTDALEQE-ILQVSSQLL---EKSRQAQ-QEQDRAREisdslsQLPQQQTEARRQLNEIERRLQTLG 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  623 dardNAQTSVTQAQ--QEKAELSQKigelhacieashqeqrqvQARVTELE-AQLKA--EQQKTTEREKVVQEKA-QLQE 696
Cdd:PRK10929   165 ----TPNTPLAQAQltALQAESAAL------------------KALVDELElAQLSAnnRQELARLRSELAKKRSqQLDA 222

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 1907176315  697 QLRALEESLKITKgsleeeKRRAADALKEqqcraTEMEAE 736
Cdd:PRK10929   223 YLQALRNQLNSQR------QREAERALES-----TELLAE 251
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1183-1697 9.07e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.91  E-value: 9.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1183 SAQRELQALRAKAQDHSKAEEEWKAQVARGQQEaerKSSLISSLEEEVsilNRQVLEKEGESKELKRLVVAESEKSQKLE 1262
Cdd:pfam12128  255 SAELRLSHLHFGYKSDETLIASRQEERQETSAE---LNQLLRTLDDQW---KEKRDELNGELSAADAAVAKDRSELEALE 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1263 ERLRLLQVETASNSARAAERSSALREEVQSLREEVE-----KQRVVSENSRQELASQAERAEELgQELKAWQEKffQKEQ 1337
Cdd:pfam12128  329 DQHGAFLDADIETAAADQEQLPSWQSELENLEERLKaltgkHQDVTAKYNRRRSKIKEQNNRDI-AGIKDKLAK--IREA 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1338 ALSALQLEHTSTQALVSELlpakhlcqqlQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQER 1417
Cdd:pfam12128  406 RDRQLAVAEDDLQALESEL----------REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1418 AAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGeRANLGRQFLEVELDQAREKYVQE----LAAVRTDA---ETHLAEM 1490
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALR-QASRRLEERQSALDELELQLFPQagtlLHFLRKEApdwEQSIGKV 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1491 RQEAQ-------------STSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAF 1557
Cdd:pfam12128  555 ISPELlhrtdldpevwdgSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGEL 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1558 -QAQRGES------QQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAkkQQNQKLQEQLQDLEELQKENKEL 1630
Cdd:pfam12128  635 eKASREETfartalKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEA--QLKQLDKKHQAWLEEQKEQKREA 712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315 1631 RSEAERLGRELQQAgLKTKEAEQTCRHLTAQVrSLEAQVAHADQQL-RDLGKFQVATDALKSREPQVK 1697
Cdd:pfam12128  713 RTEKQAYWQVVEGA-LDAQLALLKAAIAARRS-GAKAELKALETWYkRDLASLGVDPDVIAKLKREIR 778
PRK09039 PRK09039
peptidoglycan -binding protein;
456-621 9.28e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.88  E-value: 9.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  456 EDEKQQLASLIADLQSSVSNLSQAKEELeqasQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQE 535
Cdd:PRK09039    52 DSALDRLNSQIAELADLLSLERQGNQDL----QDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDS 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  536 QEQAAQGLRQQVEQLSsslklkeQQLeeaakeqEATRqdhaQQLAIVAEAREASlrerdtarqqlETVEKEKDAKLESLQ 615
Cdd:PRK09039   128 EKQVSARALAQVELLN-------QQI-------AALR----RQLAALEAALDAS-----------EKRDRESQAKIADLG 178


                   ....*.
gi 1907176315  616 QQLQAA 621
Cdd:PRK09039   179 RRLNVA 184
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 333-637 9.64e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 47.74  E-value: 9.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  333 QQLQGAFNDLieEHSKASQEWAEKQARLENE---LSTALQDKKCLEEKN---------------EILQGKlSQLEDQATR 394
Cdd:PRK10929    48 EALQSALNWL--EERKGSLERAKQYQQVIDNfpkLSAELRQQLNNERDEprsvppnmstdaleqEILQVS-SQLLEKSRQ 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  395 LQESPapEKGEVLGDAL-QLDTLKQEAAKLATD-------------------NTQLQT-------RVETLECergkqeAQ 447
Cdd:PRK10929   125 AQQEQ--DRAREISDSLsQLPQQQTEARRQLNEierrlqtlgtpntplaqaqLTALQAesaalkaLVDELEL------AQ 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  448 LLAE------RSRFEDEKQQLASLIADLQSSVSNL-SQAKEELEQASQA------QGAQLTAQLTSMTGLNATLQQrdqe 514
Cdd:PRK10929   197 LSANnrqelaRLRSELAKKRSQQLDAYLQALRNQLnSQRQREAERALEStellaeQSGDLPKSIVAQFKINRELSQ---- 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  515 laslkeqAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRqdhaQQLAIVAEAREASLRERD 594
Cdd:PRK10929   273 -------ALNQQAQRMDLIASQQRQAASQTLQVRQALNTLREQSQWLGVSNALGEALR----AQVARLPEMPKPQQLDTE 341

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1907176315  595 TARQQLETVekekdaKLESLQQQLQAANDARDNAQTSVTQAQQ 637
Cdd:PRK10929   342 MAQLRVQRL------RYEDLLNKQPQLRQIRQADGQPLTAEQN 378
PRK11637 PRK11637
AmiB activator; Provisional
 448-760 1.10e-04

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 47.00  E-value: 1.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  448 LLAERSRFEDEKQQLASLIADLqssvsnlsQAKEELEQASQaqgaqltaqltsmtglnatlQQRDQELASLKEQaKKEQA 527
Cdd:PRK11637    35 LCAFSAHASDNRDQLKSIQQDI--------AAKEKSVRQQQ--------------------QQRASLLAQLKKQ-EEAIS 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  528 QMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQleeaakeqeatrqdHAQQLAIVAEAREASLRERDTARQQLeTVEKEK 607
Cdd:PRK11637    86 QASRKLRETQNTLNQLNKQIDELNASIAKLEQQ--------------QAAQERLLAAQLDAAFRQGEHTGLQL-ILSGEE 150

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  608 DAKLESLQQQLQAANDARdnaQTSVTQAQQEKAELSQKIGELhaciEASHQEQRQVqarVTELEAQLKAEQQKTTEREKV 687
Cdd:PRK11637   151 SQRGERILAYFGYLNQAR---QETIAELKQTREELAAQKAEL----EEKQSQQKTL---LYEQQAQQQKLEQARNERKKT 220

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907176315  688 vqekaqlqeqLRALEESLKITKGSLEEEKRRAAdALKEQQCRAtEMEAESRSLMEQREREQKELEQEKAGRKG 760
Cdd:PRK11637   221 ----------LTGLESSLQKDQQQLSELRANES-RLRDSIARA-EREAKARAEREAREAARVRDKQKQAKRKG 281
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
464-904 1.38e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 46.82  E-value: 1.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  464 SLIADLQSSVSNLSQAKEELEQASQAQGAQLtAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGL 543
Cdd:COG5278     76 SFLEPYEEARAEIDELLAELRSLTADNPEQQ-ARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEI 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  544 RQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND 623
Cdd:COG5278    155 RARLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALEL 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  624 ARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEE 703
Cdd:COG5278    235 LAALALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAA 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  704 SLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHEL 783
Cdd:COG5278    315 AAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  784 AEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQ 863
Cdd:COG5278    395 IAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAAL 474

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1907176315  864 LHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVA 904
Cdd:COG5278    475 AALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEA 515
PRK11281 PRK11281
mechanosensitive channel MscK;
1375-1665 1.45e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.21  E-value: 1.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1375 KRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLgerA 1454
Cdd:PRK11281    76 DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQL---V 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1455 NLgrqfleveldQAREKYVQelaAVRTDAETHLAEMRQEAQSTSrelevmtakyEGAKVKVLEERQRFQEERQKLTAQVE 1534
Cdd:PRK11281   153 SL----------QTQPERAQ---AALYANSQRLQQIRNLLKGGK----------VGGKALRPSQRVLLQAEQALLNAQND 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1535 ELSKKLTEHDQASKV--QQQKLKAFQAQRgeSQQEVQRLQTQLNELQAQLSQKEqaaehyklqmekakthydAKKQQNQK 1612
Cdd:PRK11281   210 LQRKSLEGNTQLQDLlqKQRDYLTARIQR--LEHQLQLLQEAINSKRLTLSEKT------------------VQEAQSQD 269

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907176315 1613 LQEQLQDLEELQKE---NKELRS---EAERLGRELQQAGLKTKE----AEQTCRHLTAQVRSL 1665
Cdd:PRK11281   270 EAARIQANPLVAQEleiNLQLSQrllKATEKLNTLTQQNLRVKNwldrLTQSERNIKEQISVL 332
46 PHA02562
endonuclease subunit; Provisional
 503-725 1.49e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.93  E-value: 1.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  503 GLNATLQQRDQELASLKEQAK-------------KEQAQMLQTMQEQE-QAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQ 568
Cdd:PHA02562   178 ELNQQIQTLDMKIDHIQQQIKtynknieeqrkknGENIARKQNKYDELvEEAKTIKAEIEELTDELLNLVMDIEDPSAAL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  569 EATRQDHAQQLAIVAE-AREASLRERD----TARQQLET----VEKEKDaKLESLQQQLQAANDARDNAQ---TSVTQAQ 636
Cdd:PHA02562   258 NKLNTAAAKIKSKIEQfQKVIKMYEKGgvcpTCTQQISEgpdrITKIKD-KLKELQHSLEKLDTAIDELEeimDEFNEQS 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  637 QEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKaeqQKTTEREKVVQEKaqlqeqlraleESLKITKGSLEEEK 716
Cdd:PHA02562   337 KKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFV---DNAEELAKLQDEL-----------DKIVKTKSELVKEK 402

                          250
                   ....*....|..
gi 1907176315  717 RR---AADALKE 725
Cdd:PHA02562   403 YHrgiVTDLLKD 414
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 608-702 1.74e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 46.26  E-value: 1.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  608 DAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQV-QARVTELEAQLK-AEQQKTTERE 685
Cdd:TIGR04320  260 QAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTaQNNLATAQAALAnAEARLAKAKE 339

                           90
                   ....*....|....*..
gi 1907176315  686 KVVQEKAQLQEQLRALE 702
Cdd:TIGR04320  340 ALANLNADLAKKQAALD 356
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1467-1675 1.74e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1467 QAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQA 1546
Cdd:COG4942     37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRL 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1547 SKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKE 1626
Cdd:COG4942    117 GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAE 196

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1907176315 1627 NKELRSEAERLGRELQQAGLKTKEAEQTcrhLTAQVRSLEAQVAHADQQ 1675
Cdd:COG4942    197 RQKLLARLEKELAELAAELAELQQEAEE---LEALIARLEAEAAAAAER 242
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1514-1684 1.87e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 46.05  E-value: 1.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1514 KVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYK 1593
Cdd:COG4372      7 KVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELN 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1594 LQMEKAKTHYDAKKQQNQKLQEQL----QDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQV 1669
Cdd:COG4372     87 EQLQAAQAELAQAQEELESLQEEAeelqEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEEL 166

                          170
                   ....*....|....*
gi 1907176315 1670 AHADQQLRDLGKFQV 1684
Cdd:COG4372    167 AALEQELQALSEAEA 181
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 430-803 1.87e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.43  E-value: 1.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  430 LQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQaqgaQLTAQLTSMTGLNATLQ 509
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELR----QSREKHEELEEKYKELS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  510 QRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKeQEATRQDHAQQLAIVAEAREAS 589
Cdd:pfam07888  108 ASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGA-QRKEEEAERKQLQAKLQQTEEE 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  590 LRERDTARQQLETVEKEKDAKLESLQqqlqaanDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTE 669
Cdd:pfam07888  187 LRSLSKEFQELRNSLAQRDTQVLQLQ-------DTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEE 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  670 LEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESrslmeqrEREQK 749
Cdd:pfam07888  260 LSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAEL-------QRLEE 332

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907176315  750 ELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIRE 803
Cdd:pfam07888  333 RLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAE 386
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 508-677 2.10e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.92  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  508 LQQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEARE 587
Cdd:COG1579     12 LQELDSELDRLEHRLKELPAE-LAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  588 ASLRERD-----TARQQLETVEKEKDAKLESLQQQLQAANDARDnaqtsvtqaqQEKAELSQKIGELHACIEASHQEQRQ 662
Cdd:COG1579     91 YEALQKEieslkRRISDLEDEILELMERIEELEEELAELEAELA----------ELEAELEEKKAELDEELAELEAELEE 160

                          170
                   ....*....|....*
gi 1907176315  663 VQARVTELEAQLKAE 677
Cdd:COG1579    161 LEAEREELAAKIPPE 175
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 578-903 2.12e-04

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 45.83  E-value: 2.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  578 QLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASH 657
Cdd:pfam19220   31 QLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALREAEAAKEELR 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  658 QEQRQVQARVTELEAQLKAEqqkTTEREKVVQEKAQLQEQLRALEESLKITKGSL----------EEEKRRAADALKEQQ 727
Cdd:pfam19220  111 IELRDKTAQAEALERQLAAE---TEQNRALEEENKALREEAQAAEKALQRAEGELatarerlallEQENRRLQALSEEQA 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  728 CRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEAT----ASQHRAES------EC 797
Cdd:pfam19220  188 AELAELTRRLAELETQLDATRARLRALEGQLAAEQAERERAEAQLEEAVEAHRAERASLRmkleALTARAAAteqllaEA 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  798 ERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEihsegqpgQQQSQLAQLHASLAKAIqqvQE 877
Cdd:pfam19220  268 RNQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQFQEMQ--------RARAELEERAEMLTKAL---AA 336

                          330       340
                   ....*....|....*....|....*.
gi 1907176315  878 KEVRAQKLVDDLSALQEKMAATNKEV 903
Cdd:pfam19220  337 KDAALERAEERIASLSDRIAELTKRF 362
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 381-756 2.20e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 46.35  E-value: 2.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  381 LQGKLSQLEDQATRL-----QESPAPEKGEVLGDALQLDtlKQEAAKLATDNTQLQTRVETLECERGKQEAQLLaersRF 455
Cdd:pfam10174  298 LSKKESELLALQTKLetltnQNSDCKQHIEVLKESLTAK--EQRAAILQTEVDALRLRLEEKESFLNKKTKQLQ----DL 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  456 EDEKQQLASLIAD--------------LQSSVSNLSQA-------KEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQE 514
Cdd:pfam10174  372 TEEKSTLAGEIRDlkdmldvkerkinvLQKKIENLQEQlrdkdkqLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERI 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  515 LASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAakeqeatrQDHAQQLAivaeareASLRERD 594
Cdd:pfam10174  452 IERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDL--------KEHASSLA-------SSGLKKD 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  595 TARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTsvtqaqqeKAELSQKIGELHACIEASHQEQRQVQARVTELEAQL 674
Cdd:pfam10174  517 SKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRT--------NPEINDRIRLLEQEVARYKEESGKAQAEVERLLGIL 588

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  675 K-AEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESR-----SLMEQREREQ 748
Cdd:pfam10174  589 ReVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQqlqleELMGALEKTR 668


                   ....*...
gi 1907176315  749 KELEQEKA 756
Cdd:pfam10174  669 QELDATKA 676
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
554-908 2.25e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 45.66  E-value: 2.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  554 LKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVT 633
Cdd:COG4372     18 LRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  634 QAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREkvvQEKAQLQEQLRALEESLKITKGSLE 713
Cdd:COG4372     98 QAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAERE---EELKELEEQLESLQEELAALEQELQ 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  714 EEKRRAADALKEQQCRATEMEAEsrSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRA 793
Cdd:COG4372    175 ALSEAEAEQALDELLKEANRNAE--KEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELL 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  794 ESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQ 873
Cdd:COG4372    253 EEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELAL 332

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 1907176315  874 QVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKT 908
Cdd:COG4372    333 AILLAELADLLQLLLVGLLDNDVLELLSKGAEAGV 367
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1558-1680 2.29e-04

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 46.48  E-value: 2.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1558 QAQRGESQQEVQRLQTQLnELQAQlsQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEA-ER 1636
Cdd:PRK11448   141 ENLLHALQQEVLTLKQQL-ELQAR--EKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERkQK 217

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1907176315 1637 LGRELQQAGLKTKEAEQTCRHLTaqvrsleaqvahaDQQLRDLG 1680
Cdd:PRK11448   218 RKEITDQAAKRLELSEEETRILI-------------DQQLRKAG 248
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 513-817 2.40e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.04  E-value: 2.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  513 QELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKL---KEQQLEEAAKEQEATRQDHAQQLAIVAEAREAS 589
Cdd:pfam07888   48 QAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQsreKHEELEEKYKELSASSEELSEEKDALLAQRAAH 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  590 ---LRERDTARQQLETVEKEKDAKLESLQQ-------QLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQE 659
Cdd:pfam07888  128 earIRELEEDIKTLTQRVLERETELERMKErakkagaQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQ 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  660 QRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEE---EKRRAADALKEQQCRATEME-- 734
Cdd:pfam07888  208 VLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSmaaQRDRTQAELHQARLQAAQLTlq 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  735 -AESRSLM--------EQREREQKELEQEKAGRKGLEARIQQLEEAHQAET---EALRHELAEATASQHRAESECERLIR 802
Cdd:pfam07888  288 lADASLALregrarwaQERETLQQSAEADKDRIEKLSAELQRLEERLQEERmerEKLEVELGREKDCNRVQLSESRRELQ 367

                          330
                   ....*....|....*
gi 1907176315  803 EVESRQKRFEARQQE 817
Cdd:pfam07888  368 ELKASLRVAQKEKEQ 382
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 462-837 2.42e-04

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 45.83  E-value: 2.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  462 LASLIADLQSSVSNLSQAKEELEQAsQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQ 541
Cdd:pfam19220   22 LRSLKADFSQLIEPIEAILRELPQA-KSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALR 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  542 GLRQQVEQLSSSLKLKEQQLEEAAKeqeatrqdhaqQLAIVAEAREASLRERDTARQQLETVEK---EKDAKLESLQQQL 618
Cdd:pfam19220  101 EAEAAKEELRIELRDKTAQAEALER-----------QLAAETEQNRALEEENKALREEAQAAEKalqRAEGELATARERL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  619 QAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQAR-VTELEAQLKAEQQKTTEREKVVQEKAQLQEQ 697
Cdd:pfam19220  170 ALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEGQlAAEQAERERAEAQLEEAVEAHRAERASLRMK 249

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  698 LRALEESLKITKgSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETE 777
Cdd:pfam19220  250 LEALTARAAATE-QLLAEARNQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQFQEMQRARAELEERAE 328

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  778 ALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKT 837
Cdd:pfam19220  329 MLTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAALEQANRRLKEELQRERAERA 388
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1153-1357 2.93e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 2.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1153 RAEQDKALETLQGQLEEKARELghnqaasASAQRELQALRAKAQdhskaeeewkaqVARGQQEAERKSSLISSLEEEVSI 1232
Cdd:COG3206    170 REEARKALEFLEEQLPELRKEL-------EEAEAALEEFRQKNG------------LVDLSEEAKLLLQQLSELESQLAE 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1233 LNRQVLEKEGESKELKRLV---------VAESEKSQKLEERLRLLQVETASNSARAAERSS---ALREEVQSLREEVEKQ 1300
Cdd:COG3206    231 ARAELAEAEARLAALRAQLgsgpdalpeLLQSPVIQQLRAQLAELEAELAELSARYTPNHPdviALRAQIAALRAQLQQE 310

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176315 1301 -RVVSENSRQELASQAERAEELGQELKAWQEKFF---QKEQALSALQLEHTSTQALVSELL 1357
Cdd:COG3206    311 aQRILASLEAELEALQAREASLQAQLAQLEARLAelpELEAELRRLEREVEVARELYESLL 371
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1146-1342 3.28e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 45.82  E-value: 3.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1146 LKSERACRAEQDKA------LETLQGQLEEKARELghnqaasASAQRELQALRAKAQDHSKAeeewkaQVARGQQEAERK 1219
Cdd:PRK10929   119 LEKSRQAQQEQDRAreisdsLSQLPQQQTEARRQL-------NEIERRLQTLGTPNTPLAQA------QLTALQAESAAL 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1220 SSLISSLE-EEVSILNRQvlekegeskELKRLvvaESEKSQKLEERL--RLLQVETASNSAR------AAERSSALREEV 1290
Cdd:PRK10929   186 KALVDELElAQLSANNRQ---------ELARL---RSELAKKRSQQLdaYLQALRNQLNSQRqreaerALESTELLAEQS 253

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907176315 1291 QSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSAL 1342
Cdd:PRK10929   254 GDLPKSIVAQFKINRELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTL 305
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
357-571 3.47e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 3.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  357 QARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQES----PAPEKGEVLGDalQLDTLKQEAAKLATDNTQLQT 432
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKnglvDLSEEAKLLLQ--QLSELESQLAEARAELAEAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  433 RVETLE--CERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLS-------QAKEELEQASQAQGAQLTAQLTSMTG 503
Cdd:COG3206    241 RLAALRaqLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTpnhpdviALRAQIAALRAQLQQEAQRILASLEA 320

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315  504 LNATLQQRDQELASLKEQAKKEqaqmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 571
Cdd:COG3206    321 ELEALQAREASLQAQLAQLEAR----LAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALT 384
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1159-1679 3.59e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.10  E-value: 3.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1159 ALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKA------QVARGQQEAERKSSL----ISSLEE 1228
Cdd:COG3096    362 RLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTraiqyqQAVQALEKARALCGLpdltPENAED 441

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1229 EVSILNRQVLEKEGESKELK-RLVVAESEKSQkLEERLRLLQvetasNSARAAERSSALREEVQSLREEVEKQRVVSENS 1307
Cdd:COG3096    442 YLAAFRAKEQQATEEVLELEqKLSVADAARRQ-FEKAYELVC-----KIAGEVERSQAWQTARELLRRYRSQQALAQRLQ 515

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1308 --RQELA------SQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFRE 1379
Cdd:COG3096    516 qlRAQLAeleqrlRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIK 595

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1380 ELEQSKQAAGGLQAELMRAQRELGE-------LGSLRQKIVEQERAAQ----QLRAEKASYAEQLSMLKKAHGLLAEENR 1448
Cdd:COG3096    596 ELAARAPAWLAAQDALERLREQSGEaladsqeVTAAMQQLLEREREATverdELAARKQALESQIERLSQPGGAEDPRLL 675

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1449 GLGERAN---LGRQFLEVELDQARE---KY--------VQELAAVRT------DAETHLAEMRQEAQS---TSRELEVMt 1505
Cdd:COG3096    676 ALAERLGgvlLSEIYDDVTLEDAPYfsaLYgparhaivVPDLSAVKEqlagleDCPEDLYLIEGDPDSfddSVFDAEEL- 754

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1506 akyEGAKVKVLEERQ----RF----------QEER-QKLTAQVEELSKkltEHDQASKVQQ------QKLKAFQAQ---- 1560
Cdd:COG3096    755 ---EDAVVVKLSDRQwrysRFpevplfgraaREKRlEELRAERDELAE---QYAKASFDVQklqrlhQAFSQFVGGhlav 828

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1561 --RGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYdakkQQNQKLQEQL-----QDLEELQKENKELRSE 1633
Cdd:COG3096    829 afAPDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQL----QLLNKLLPQAnlladETLADRLEELREELDA 904

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 1907176315 1634 AERLGRELQQAGLKTKEAE---QTCRHLTAQVRSLEAQVAHADQQLRDL 1679
Cdd:COG3096    905 AQEAQAFIQQHGKALAQLEplvAVLQSDPEQFEQLQADYLQAKEQQRRL 953
KpsE COG3524
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
445-584 3.91e-04

Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442746 [Multi-domain]  Cd Length: 370  Bit Score: 45.23  E-value: 3.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  445 EAQLLAERSRFEDEKQQLASL-----IADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLK 519
Cdd:COG3524    183 EEEVERAEERLRDAREALLAFrnrngILDPEATAEALLQLIATLEGQLAELEAELAALRSYLSPNSPQVRQLRRRIAALE 262

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315  520 EQAKKEQAQMlqTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQ---LAIVAE 584
Cdd:COG3524    263 KQIAAERARL--TGASGGDSLASLLAEYERLELEREFAEKAYTSALAALEQARIEAARQqryLAVIVQ 328
mukB PRK04863
chromosome partition protein MukB;
1272-1669 3.93e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 3.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1272 TASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFfQKEQALSALQLEHTSTQA 1351
Cdd:PRK04863   277 HANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKIERYQA 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1352 LVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELgslrQKIVEQERAAQQL--RAEKASY 1429
Cdd:PRK04863   356 DLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQ----QTRAIQYQQAVQAleRAKQLCG 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1430 AEQLSmLKKAHGLLAE---ENRGLGERANLGRQFLEVElDQAREKYVQELAAVRTDAethlAEM-RQEAQSTSRELEvmt 1505
Cdd:PRK04863   432 LPDLT-ADNAEDWLEEfqaKEQEATEELLSLEQKLSVA-QAAHSQFEQAYQLVRKIA----GEVsRSEAWDVARELL--- 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1506 akyegakvkvleerqRFQEERQKLTAQVEELSKKLTEHDQASKVQQQklkAFQAQRGESQQEVQRLQTQlNELQAQLSQK 1585
Cdd:PRK04863   503 ---------------RRLREQRHLAEQLQQLRMRLSELEQRLRQQQR---AERLLAEFCKRLGKNLDDE-DELEQLQEEL 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1586 EQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRE--------------LQQAGLKTKEA 1651
Cdd:PRK04863   564 EARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQsgeefedsqdvteyMQQLLEREREL 643

                          410
                   ....*....|....*...
gi 1907176315 1652 EQTCRHLTAQVRSLEAQV 1669
Cdd:PRK04863   644 TVERDELAARKQALDEEI 661
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 211-483 4.12e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 4.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  211 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHL-ALLNEKQAASSQEPSELEELRGKNESLTVR 289
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALrEALDELRAELTLLNEEAANLRERLESLERR 832

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  290 LHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREF---ANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELST 366
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELeseLEALLNERASLEEALALLRSELEELSEELRELESKRSE 912

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  367 ALQDKKCLEEKNEILQGKLSQLEDQATRLQESpAPEKGEVLgdalqLDTLKQEAAKLATDNTQLQTRVETLECERGK--- 443
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQER-LSEEYSLT-----LEEAEALENKIEDDEEEARRRLKRLENKIKElgp 986

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1907176315  444 ------QEAQLLAERSRFedekqqLASLIADLQSSVSNLSQAKEEL 483
Cdd:TIGR02168  987 vnlaaiEEYEELKERYDF------LTAQKEDLTEAKETLEEAIEEI 1026
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
543-680 4.17e-04

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 44.65  E-value: 4.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  543 LRQQVEQLSSSLKLKEQQLEeAAKEQEATRQDHAQQLAIVAEAREaslrERDTARQQLETVEKEKDAKLESlQQQLQAAN 622
Cdd:COG1566     81 LQAALAQAEAQLAAAEAQLA-RLEAELGAEAEIAAAEAQLAAAQA----QLDLAQRELERYQALYKKGAVS-QQELDEAR 154

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176315  623 DARDNAQTSVTQAQqekAELSQKIGELhacieASHQEQRQVQARVTELEAQLKAEQQK 680
Cdd:COG1566    155 AALDAAQAQLEAAQ---AQLAQAQAGL-----REEEELAAAQAQVAQAEAALAQAELN 204
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 459-1219 4.56e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.49  E-value: 4.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  459 KQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTaqlTSMTGLNATLQQRDQELASLKEQAKKEQaqmlqtmQEQEQ 538
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLR---QSVIDLQTKLQEMQMERDAMADIRRRES-------QSQED 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  539 AAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAR-------EAS---LRERDTAR----------- 597
Cdd:pfam15921  143 LRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRsilvdfeEASgkkIYEHDSMStmhfrslgsai 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  598 ----QQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAElsQKIGELHACIEASHQEQRQVQARVTELEAQ 673
Cdd:pfam15921  223 skilRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIE--QLISEHEVEITGLTEKASSARSQANSIQSQ 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  674 LKAEQqktterEKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAEsrsLMEQRErEQKELEQ 753
Cdd:pfam15921  301 LEIIQ------EQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSE---LTEART-ERDQFSQ 370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  754 EKAgrkGLEARIQQ-LEEAHQAETE-ALRHELAEATASQHRAESecerliREVESRQKRFEARQQEEARYGAMfqeqLMA 831
Cdd:pfam15921  371 ESG---NLDDQLQKlLADLHKREKElSLEKEQNKRLWDRDTGNS------ITIDHLRRELDDRNMEVQRLEAL----LKA 437

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  832 LKGEKTGQeVQEEAVEIHSEGQPGQQQSQL-AQLHAS---LAKAIQQVQEKEV---RAQKLVDDLSA-LQEK---MAATN 900
Cdd:pfam15921  438 MKSECQGQ-MERQMAAIQGKNESLEKVSSLtAQLESTkemLRKVVEELTAKKMtleSSERTVSDLTAsLQEKeraIEATN 516

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  901 KEVACLKTLV-LKAGE--------------QQETASLEL-------LKEPPRAANRASDQLGEQQGRPFSSTHAAVKAME 958
Cdd:pfam15921  517 AEITKLRSRVdLKLQElqhlknegdhlrnvQTECEALKLqmaekdkVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLE 596

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  959 REAEQMGGELERLRA------ALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEF 1032
Cdd:pfam15921  597 KEINDRRLELQEFKIlkdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDY 676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1033 AALQEALAHALTEKEGTDQELaklrgqeaaqRTELKELQQTLEQLKIQLVKKEkehpaggasGEDASGPGTQSETAGKTD 1112
Cdd:pfam15921  677 EVLKRNFRNKSEEMETTTNKL----------KMQLKSAQSELEQTRNTLKSME---------GSDGHAMKVAMGMQKQIT 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1113 APGPELQALRAEISKLEqqcqqqqqqvEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRelqaLR 1192
Cdd:pfam15921  738 AKRGQIDALQSKIQFLE----------EAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERR----LK 803

                          810       820
                   ....*....|....*....|....*..
gi 1907176315 1193 AKAQDHSKAEEEWKAQVARGQQEAERK 1219
Cdd:pfam15921  804 EKVANMEVALDKASLQFAECQDIIQRQ 830
mukB PRK04863
chromosome partition protein MukB;
1150-1645 4.65e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 4.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1150 RACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQdhskaeeewKAQVARGQQEAERKSSliSSLEEe 1229
Cdd:PRK04863   292 RRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLN---------LVQTALRQQEKIERYQ--ADLEE- 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1230 vsilnrqvlekegeskelkrlvvaeseksqkLEERLrllqvetasnsaraaERSSALREEVQSLREEVEKQRVVSENSRQ 1309
Cdd:PRK04863   360 -------------------------------LEERL---------------EEQNEVVEEADEQQEENEARAEAAEEEVD 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1310 ELASQaerAEELGQELKAWQEKFFQKEQALSALQlehtstqalvsellPAKHLCQQlqaeqaaaekrfrEELEQSKqaAG 1389
Cdd:PRK04863   394 ELKSQ---LADYQQALDVQQTRAIQYQQAVQALE--------------RAKQLCGL-------------PDLTADN--AE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1390 GLQAELMRAQRELG-ELGSLRQKIVEQERAAQQlraekasYAEQLSMLKKAHGLLaeenrglgERANLGRQFLEVELDQA 1468
Cdd:PRK04863   442 DWLEEFQAKEQEATeELLSLEQKLSVAQAAHSQ-------FEQAYQLVRKIAGEV--------SRSEAWDVARELLRRLR 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1469 REKYvqeLAAVRTDAETHLAEMRQEAQStSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASK 1548
Cdd:PRK04863   507 EQRH---LAEQLQQLRMRLSELEQRLRQ-QQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRM 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1549 VQQQKLKAFQAQRgesqQEVQRLQTQLNELQAQLSQ-KEQAAEhyklqmekaktHYDAKKQQNQKLQEQLQDLEELQKEN 1627
Cdd:PRK04863   583 ALRQQLEQLQARI----QRLAARAPAWLAAQDALARlREQSGE-----------EFEDSQDVTEYMQQLLERERELTVER 647

                          490       500
                   ....*....|....*....|.
gi 1907176315 1628 KELRSEAERLGRE---LQQAG 1645
Cdd:PRK04863   648 DELAARKQALDEEierLSQPG 668
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1514-1675 5.37e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 5.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1514 KVLEERQRFQEERQKLTAQVEELSKKLTE--HDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEH 1591
Cdd:COG4717     85 EKEEEYAELQEELEELEEELEELEAELEElrEELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEE 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1592 YK-LQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAglktkeaEQTCRHLTAQVRSLEAQVA 1670
Cdd:COG4717    165 LEeLEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA-------QEELEELEEELEQLENELE 237


                   ....*
gi 1907176315 1671 HADQQ 1675
Cdd:COG4717    238 AAALE 242
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 1510-1634 5.42e-04

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 45.04  E-value: 5.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1510 GAKVKVLEERQRFQEERQKLTAQVEELSKKLTE--HDQASKVQQQK--LKAFQAQ-------RGESQQEVQRLQTQLNEL 1578
Cdd:pfam10168  568 LQKEQQLQELQSLEEERKSLSERAEKLAEKYEEikDKQEKLMRRCKkvLQRLNSQlpvlsdaEREMKKELETINEQLKHL 647

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315 1579 QAQLSQKEQAAEHYKLQMEKAKTHYDA---------KKQQNQKLQEQLQDLEELQKENKELRSEA 1634
Cdd:pfam10168  648 ANAIKQAKKKMNYQRYQIAKSQSIRKKsslslsekqRKTIKEILKQLGSEIDELIKQVKDINKHV 712
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 466-693 5.54e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 5.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  466 IADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQ 545
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  546 QVEQLSSSLKLKEQQ-LEEAAkeqeatrqDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDA 624
Cdd:COG3883     98 SGGSVSYLDVLLGSEsFSDFL--------DRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315  625 RDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQ 693
Cdd:COG3883    170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1444-1679 5.61e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.33  E-value: 5.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1444 AEENRGLGERANLGRQflevELDQAREKyvqelaavRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAK--VKVLEERQR 1521
Cdd:COG3096    277 ANERRELSERALELRR----ELFGARRQ--------LAEEQYRLVEMARELEELSARESDLEQDYQAASdhLNLVQTALR 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1522 FQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQ----------AQLSQKEQAAEH 1591
Cdd:COG3096    345 QQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQqaldvqqtraIQYQQAVQALEK 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1592 YKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQA---------GLKTKEAEQTCRHLTAQV 1662
Cdd:COG3096    425 ARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAyelvckiagEVERSQAWQTARELLRRY 504

                          250       260
                   ....*....|....*....|
gi 1907176315 1663 RSLEAQVAHADQ---QLRDL 1679
Cdd:COG3096    505 RSQQALAQRLQQlraQLAEL 524
PRK09039 PRK09039
peptidoglycan -binding protein;
568-721 5.85e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.57  E-value: 5.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  568 QEATRQDHA-----QQLAIVAEAreASLRERdtARQQLEtvekekdAKLESLQQQLQAANDARDNAQTSVTQAQQEKAEL 642
Cdd:PRK09039    46 REISGKDSAldrlnSQIAELADL--LSLERQ--GNQDLQ-------DSVANLRASLSAAEAERSRLQALLAELAGAGAAA 114

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315  643 SQKIGELHACIEASHQEQRQVQARVTELEAQLkaeqqktterekvvqekAQLQEQLRALEESLKITKGSLEEEKRRAAD 721
Cdd:PRK09039   115 EGRAGELAQELDSEKQVSARALAQVELLNQQI-----------------AALRRQLAALEAALDASEKRDRESQAKIAD 176
PRK09039 PRK09039
peptidoglycan -binding protein;
1523-1644 5.96e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.19  E-value: 5.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1523 QEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQ-------KEQAAEHYKLQ 1595
Cdd:PRK09039    52 DSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAaegrageLAQELDSEKQV 131

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176315 1596 MEKAKTHYDAKKQQNQKLQEQLQDLEEL----QKENKELRSEAERLGRELQQA 1644
Cdd:PRK09039   132 SARALAQVELLNQQIAALRRQLAALEAAldasEKRDRESQAKIADLGRRLNVA 184
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 459-562 6.25e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 44.33  E-value: 6.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  459 KQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQltsmTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQ 538
Cdd:TIGR04320  253 PNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAY----AAAQAALATAQKELANAQAQALQTAQNNLATAQAALA 328

                           90       100
                   ....*....|....*....|....*...
gi 1907176315  539 AAQG----LRQQVEQLSSSLKLKEQQLE 562
Cdd:TIGR04320  329 NAEArlakAKEALANLNADLAKKQAALD 356
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1281-1681 6.84e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 6.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1281 ERSSALREEVQSLREEVEkqrvvsensrqELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEllpak 1360
Cdd:PRK02224   206 ERLNGLESELAELDEEIE-----------RYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAE----- 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1361 hlcqqlqaeQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGeLGSLRQKIVEQERAAqqLRAEKASYAEQLSMLKKAH 1440
Cdd:PRK02224   270 ---------TEREREELAEEVRDLRERLEELEEERDDLLAEAG-LDDADAEAVEARREE--LEDRDEELRDRLEECRVAA 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1441 GLLAEENRGLGERANLgrqfLEVELDQAREKyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKV---KVLE 1517
Cdd:PRK02224   338 QAHNEEAESLREDADD----LEERAEELREE-AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVdlgNAED 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1518 ERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQ--------------AQRGESQQEVQRLQTQLNELQAQLS 1583
Cdd:PRK02224   413 FLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvETIEEDRERVEELEAELEDLEEEVE 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1584 QKEQAAEHYKlQMEKAKTHYDAKKQQNQKLQEQLQD----LEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLT 1659
Cdd:PRK02224   493 EVEERLERAE-DLVEAEDRIERLEERREDLEELIAErretIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR 571

                          410       420
                   ....*....|....*....|..
gi 1907176315 1660 AQVRSLEAQVAHADQQLRDLGK 1681
Cdd:PRK02224   572 EEVAELNSKLAELKERIESLER 593
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 660-874 7.21e-04

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 44.07  E-value: 7.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  660 QRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKItkgslEEEKRRAADALKEQQCRATEMEAESRS 739
Cdd:TIGR02794   66 EQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQ-----AEEKQKQAEEAKAKQAAEAKAKAEAEA 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  740 LMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRfEARQQEEA 819
Cdd:TIGR02794  141 ERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAKAEAAKAKAAAEAAA-KAEAEAAA 219

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315  820 RYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQ 874
Cdd:TIGR02794  220 AAAAEAERKADEAELGDIFGLASGSNAEKQGGARGAAAGSEVDKYAAIIQQAIQQ 274
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1534-1643 7.69e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.46  E-value: 7.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1534 EELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKL 1613
Cdd:COG2433    388 KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERREIRKDREI 467

                           90       100       110
                   ....*....|....*....|....*....|
gi 1907176315 1614 QEQLQDLEELQKENKELRSEAERLGRELQQ 1643
Cdd:COG2433    468 SRLDREIERLERELEEERERIEELKRKLER 497
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1278-1644 7.84e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.67  E-value: 7.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1278 RAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELL 1357
Cdd:PRK03918   162 NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1358 PAKhlcqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERaaqqLRAEKASYAEQLSMLK 1437
Cdd:PRK03918   242 ELE----KELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK----LSEFYEEYLDELREIE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1438 KAHGLLAEENRGLGERanlgrqfleveLDQAREKyvqelaavrtdaETHLAEMRQEAQSTSRELEVMTAK---YEGAKVK 1514
Cdd:PRK03918   314 KRLSRLEEEINGIEER-----------IKELEEK------------EERLEELKKKLKELEKRLEELEERhelYEEAKAK 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1515 vLEERQRFQEERQKLTaqVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQ-----LSQKEQAA 1589
Cdd:PRK03918   371 -KEELERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpVCGRELTE 447

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315 1590 EHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQA 1644
Cdd:PRK03918   448 EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELA 502
PRK09039 PRK09039
peptidoglycan -binding protein;
504-674 7.94e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.80  E-value: 7.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  504 LNATLQQRDQELASLKEQAkkeqAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkeqqleeAAKEQEatrQDHAQQLAIVA 583
Cdd:PRK09039    44 LSREISGKDSALDRLNSQI----AELADLLSLERQGNQDLQDSVANLRASL---------SAAEAE---RSRLQALLAEL 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  584 EAREASLRERDTarqqletvekEKDAKLESLQQQlqaanDARDNAQTSVTQAQQekAELSQKIGELHACIEASHQEQRQV 663
Cdd:PRK09039   108 AGAGAAAEGRAG----------ELAQELDSEKQV-----SARALAQVELLNQQI--AALRRQLAALEAALDASEKRDRES 170

                          170
                   ....*....|.
gi 1907176315  664 QARVTELEAQL 674
Cdd:PRK09039   171 QAKIADLGRRL 181
PLN02939 PLN02939
transferase, transferring glycosyl groups
 357-563 8.21e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.51  E-value: 8.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  357 QARLE--NELSTALQDKKCLEEKNEILQGKLS---------------------QLEDQATRLQESPAPEKGEVLGDALQL 413
Cdd:PLN02939   149 QARLQalEDLEKILTEKEALQGKINILEMRLSetdariklaaqekihveileeQLEKLRNELLIRGATEGLCVHSLSKEL 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  414 DTLKQEAAKLATDNTQLQTRVETLEcERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQ 493
Cdd:PLN02939   229 DVLKEENMLLKDDIQFLKAELIEVA-ETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVENLQD 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  494 LTAQLTSMTGLNATLQQRDQEL--------ASLKE-QAKKEQAQMLQTMQEQEQAAQG-LRQQVEQLSSSLKLKEQQLEE 563
Cdd:PLN02939   308 LLDRATNQVEKAALVLDQNQDLrdkvdkleASLKEaNVSKFSSYKVELLQQKLKLLEErLQASDHEIHSYIQLYQESIKE 387
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 402-574 8.49e-04

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 43.95  E-value: 8.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  402 EKGEVLgdaLQLDTLKQEAAKLATDNTQLQTRvetlecergKQEAQLLAERSRFE-------DEKQQLASLIADLQSSVS 474
Cdd:pfam00529   43 KAGDVL---FQLDPTDYQAALDSAEAQLAKAQ---------AQVARLQAELDRLQaleselaISRQDYDGATAQLRAAQA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  475 NLSQAKEELEQA-SQAQGAQLTAQLTSMTGlnATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSS 553
Cdd:pfam00529  111 AVKAAQAQLAQAqIDLARRRVLAPIGGISR--ESLVTAGALVAQAQANLLATVAQLDQIYVQITQSAAENQAEVRSELSG 188

                          170       180
                   ....*....|....*....|.
gi 1907176315  554 LklkEQQLEEAAKEQEATRQD 574
Cdd:pfam00529  189 A---QLQIAEAEAELKLAKLD 206
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 994-1213 8.74e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  994 ARLTQERGQAQADLAQEKAAKAELEMR---LQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKEL 1070
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEekaLLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1071 QQTLEQLKIQLVKKEK-EHPAGGASGEDASGPGTQSETAGK-TDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKS 1148
Cdd:COG4942    103 KEELAELLRALYRLGRqPPLALLLSPEDFLDAVRRLQYLKYlAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176315 1149 ERACR-------AEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQ 1213
Cdd:COG4942    183 LEEERaalealkAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGK 254
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 516-638 9.34e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.43  E-value: 9.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  516 ASLKEQAKKeqaqmlqtMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQlaIVAEAR-EASLRERD 594
Cdd:PRK00409   523 ASLEELERE--------LEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQ--AIKEAKkEADEIIKE 592

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1907176315  595 TARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQE 638
Cdd:PRK00409   593 LRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEE 636
PRK12705 PRK12705
hypothetical protein; Provisional
 614-777 9.74e-04

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 43.93  E-value: 9.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  614 LQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhaCIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQ 693
Cdd:PRK12705    25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKEL--LLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDN 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  694 LQEQLRALEESLKITKGSLEEEKRRAADALKEqqcRATEMEAESRSLMEQreREQKELEQEKAgrkgleARIQQLEEAHQ 773
Cdd:PRK12705   103 LENQLEEREKALSARELELEELEKQLDNELYR---VAGLTPEQARKLLLK--LLDAELEEEKA------QRVKKIEEEAD 171


                   ....
gi 1907176315  774 AETE 777
Cdd:PRK12705   172 LEAE 175
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1527-1679 1.02e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.99  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1527 QKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTH--YD 1604
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNkeYE 92

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315 1605 AKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQaglktkEAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1679
Cdd:COG1579     93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEA------ELAELEAELEEKKAELDEELAELEAELEEL 161
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 850-1120 1.03e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  850 SEGQpgQQQSQLAQlHASLAKAIQQVQEKEVRA-----------QKLVDDLSALQEKMAATNKEVACLKTLVLKAG--EQ 916
Cdd:NF012221  1538 SESS--QQADAVSK-HAKQDDAAQNALADKERAeadrqrleqekQQQLAAISGSQSQLESTDQNALETNGQAQRDAilEE 1614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  917 QETASLELLKEPPR-AANRASDQLGEQQGRPFSsTHAAVKAMEREAEQM-------GGELERLRAALIKSQGQQQEERGQ 988
Cdd:NF012221  1615 SRAVTKELTTLAQGlDALDSQATYAGESGDQWR-NPFAGGLLDRVQEQLddakkisGKQLADAKQRHVDNQQKVKDAVAK 1693

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  989 QEREVARLTQERGQAQADLAQekaAKAELEMRLQNTLNEQRVefAALQEALAHALTEKegtdqelAKLRGQEAAQRTELK 1068
Cdd:NF012221  1694 SEAGVAQGEQNQANAEQDIDD---AKADAEKRKDDALAKQNE--AQQAESDANAAAND-------AQSRGEQDASAAENK 1761

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176315 1069 ELQQTLEQLKIQLVKKEKEHPAgGASGEDASGPGTQSETAGKTD-APGPELQA 1120
Cdd:NF012221  1762 ANQAQADAKGAKQDESDKPNRQ-GAAGSGLSGKAYSVEGVAEPGsHINPDSPA 1813
mukB PRK04863
chromosome partition protein MukB;
298-564 1.07e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.18  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  298 QNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQ---GAFNDLIEEHskasqeWAEKQARLENELSTALQDKKCL 374
Cdd:PRK04863   840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNrllPRLNLLADET------LADRVEEIREQLDEAEEAKRFV 913

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  375 EEKneilQGKLSQLEDQATRLQESP---APEKGEVLGDALQLDTLKQ------------------EAAKLATDNT----Q 429
Cdd:PRK04863   914 QQH----GNALAQLEPIVSVLQSDPeqfEQLKQDYQQAQQTQRDAKQqafaltevvqrrahfsyeDAAEMLAKNSdlneK 989

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  430 LQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEqasqaqgaQLTAQLTSmtGLNATLQ 509
Cdd:PRK04863   990 LRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQ--------DLGVPADS--GAEERAR 1059

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315  510 QRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEA 564
Cdd:PRK04863  1060 ARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNA 1114
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1211-1640 1.12e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 43.96  E-value: 1.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1211 RGQQEAERKSS-LISSLEEEVSilnrQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSAL--- 1286
Cdd:pfam05557   27 RARIELEKKASaLKRQLDRESD----RNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLada 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1287 REEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqql 1366
Cdd:pfam05557  103 REVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAEQRI---------- 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1367 qaeqaaaekrfrEELEQSKQAAGGLQAELMRAQRELGelgslrqKIVEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEE 1446
Cdd:pfam05557  173 ------------KELEFEIQSQEQDSEIVKNSKSELA-------RIPELEKELERLREHN----KHLNENIENKLLLKEE 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1447 NRGLgeRANLGRQ--------FLEVELdqarEKYVQELAAVRTDAETHLAEMR-------QEAQSTSRELEVMTAKYEGA 1511
Cdd:pfam05557  230 VEDL--KRKLEREekyreeaaTLELEK----EKLEQELQSWVKLAQDTGLNLRspedlsrRIEQLQQREIVLKEENSSLT 303

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1512 KVKVLEERQR--FQEERQKLTAQVEELSKKLTEHD-QASKVQQQKLKAFQAQRG-------------------------- 1562
Cdd:pfam05557  304 SSARQLEKARreLEQELAQYLKKIEDLNKKLKRHKaLVRRLQRRVLLLTKERDGyrailesydkeltmsnyspqllerie 383

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1563 ESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQL--QDLEELQKENKELRSEAERLGRE 1640
Cdd:pfam05557  384 EAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYskEEVDSLRRKLETLELERQRLREQ 463
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 610-788 1.13e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.99  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  610 KLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKtterekvvQ 689
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ--------L 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  690 EKAQLQEQLRALEESLKitkgSLEEEKRRAADALKEqqcratemeaesrsLMEQREREQKELEQEKAGRKGLEARIQQLE 769
Cdd:COG1579     83 GNVRNNKEYEALQKEIE----SLKRRISDLEDEILE--------------LMERIEELEEELAELEAELAELEAELEEKK 144

                          170
                   ....*....|....*....
gi 1907176315  770 EAHQAETEALRHELAEATA 788
Cdd:COG1579    145 AELDEELAELEAELEELEA 163
mukB PRK04863
chromosome partition protein MukB;
1118-1679 1.13e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.18  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1118 LQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKaLETLQGQLEEKARELGHNQAASASAQRELQALRAKAQD 1197
Cdd:PRK04863   309 LVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEK-IERYQADLEELEERLEEQNEVVEEADEQQEENEARAEA 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1198 HSKAEEEWKAQVARGQQ---EAERKSS----LISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQK---LEERLRL 1267
Cdd:PRK04863   388 AEEEVDELKSQLADYQQaldVQQTRAIqyqqAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEEllsLEQKLSV 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1268 L-----QVETASNSARAA----ERSSALREEVQSLREeVEKQRVVSENS----------RQELASQAeRAEELGQELKAW 1328
Cdd:PRK04863   468 AqaahsQFEQAYQLVRKIagevSRSEAWDVARELLRR-LREQRHLAEQLqqlrmrlselEQRLRQQQ-RAERLLAEFCKR 545

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1329 QEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGE---- 1404
Cdd:PRK04863   546 LGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEefed 625

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1405 ---LGSLRQKIVEQERAAQQ----LRAEKASYAEQLSMLKKAHGLLAEENRGLGERAN---LGRQFLEVELDQAreKYVQ 1474
Cdd:PRK04863   626 sqdVTEYMQQLLERERELTVerdeLAARKQALDEEIERLSQPGGSEDPRLNALAERFGgvlLSEIYDDVSLEDA--PYFS 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1475 EL------AAVRTD---AETHLAEMR-------------QEAQSTSRELEVMtakyEGAKVKVLEERQ----RFQEE--- 1525
Cdd:PRK04863   704 ALygparhAIVVPDlsdAAEQLAGLEdcpedlyliegdpDSFDDSVFSVEEL----EKAVVVKIADRQwrysRFPEVplf 779

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1526 ----RQKLTAQV-EELSKKLTEHDQAS----KVQQ--QKLKAFQAQ------RGESQQEVQRLQTQLNELQAQLSQKEQA 1588
Cdd:PRK04863   780 graaREKRIEQLrAEREELAERYATLSfdvqKLQRlhQAFSRFIGShlavafEADPEAELRQLNRRRVELERALADHESQ 859

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1589 AEHYKLQMEKAKTHYdakkQQNQKLQEQ--LQDLEELQKENKELRSE---AERLGRELQQAGLKTKEAEQ---TCRHLTA 1660
Cdd:PRK04863   860 EQQQRSQLEQAKEGL----SALNRLLPRlnLLADETLADRVEEIREQldeAEEAKRFVQQHGNALAQLEPivsVLQSDPE 935

                          650
                   ....*....|....*....
gi 1907176315 1661 QVRSLEAQVAHADQQLRDL 1679
Cdd:PRK04863   936 QFEQLKQDYQQAQQTQRDA 954
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
929-1344 1.13e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  929 PRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALikSQGQQQEERGQQEREVARLTQERGQAQADLA 1008
Cdd:COG4717     65 KPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAEL--EELREELEKLEKLLQLLPLYQELEALEAELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1009 QEKAAKAELEMR------LQNTLNEQRVEFAALQEALAHALTEK--------EGTDQELAKLRGQEAAQRTELKELQQTL 1074
Cdd:COG4717    143 ELPERLEELEERleelreLEEELEELEAELAELQEELEELLEQLslateeelQDLAEELEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1075 EQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRA 1154
Cdd:COG4717    223 EELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGK 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1155 EQDK-----ALETLQGQ-LEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEE 1228
Cdd:COG4717    303 EAEElqalpALEELEEEeLEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVE 382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1229 EVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETAsnsARAAERSSALREEVQSLREEVEK--QRVVSEN 1306
Cdd:COG4717    383 DEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE---EELEEELEELEEELEELEEELEElrEELAELE 459

                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 1907176315 1307 SRQELASQAERAEELGQELKAWQEKFFQKEQALSALQL 1344
Cdd:COG4717    460 AELEQLEEDGELAELLQELEELKAELRELAEEWAALKL 497
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 460-621 1.19e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  460 QQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQA 539
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  540 AqgLRQQVEqlssSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQ 619
Cdd:COG1579     93 A--LQKEIE----SLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAERE 166


                   ..
gi 1907176315  620 AA 621
Cdd:COG1579    167 EL 168
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 669-817 1.19e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  669 ELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQRERE- 747
Cdd:COG1579     14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEa 93

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176315  748 -QKELEQEKAGRKGLEARIQQLE---EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQE 817
Cdd:COG1579     94 lQKEIESLKRRISDLEDEILELMeriEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREE 167
TOPEUc smart00435
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ...
 1595-1678 1.53e-03

DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras


Pssm-ID: 214661 [Multi-domain]  Cd Length: 391  Bit Score: 43.11  E-value: 1.53e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  1595 QMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ 1674
Cdd:smart00435  278 SMEKLQEKIKALKYQLKRLKKMILLFEMISDLKRKLKSKFERDNEKLDAEVKEKKKEKKKEEKKKKQIERLEERIEKLEV 357


                    ....
gi 1907176315  1675 QLRD 1678
Cdd:smart00435  358 QATD 361
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 569-761 1.55e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 43.45  E-value: 1.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  569 EATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAK---LESLQQQLQAANDARDNAQTSVTQAQQEKAELSQK 645
Cdd:pfam05262  184 EALREDNEKGVNFRRDMTDLKERESQEDAKRAQQLKEELDKKqidADKAQQKADFAQDNADKQRDEVRQKQQEAKNLPKP 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  646 igelhacieashqeqrqvqARVTEleaqlKAEQQKTTEREKVVQEKAQlQEQLRALEESLKitkgsleeEKRRAADALKe 725
Cdd:pfam05262  264 -------------------ADTSS-----PKEDKQVAENQKREIEKAQ-IEIKKNDEEALK--------AKDHKAFDLK- 309

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1907176315  726 QQCRATEMEAESRSLMEQRERE------QKELEQEKAGRKGL 761
Cdd:pfam05262  310 QESKASEKEAEDKELEAQKKREpvaedlQKTKPQVEAQPTSL 351
GBP_C pfam02841
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...
 669-817 1.64e-03

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.


Pssm-ID: 460721 [Multi-domain]  Cd Length: 297  Bit Score: 42.66  E-value: 1.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  669 ELEAQLKAEQQKTTEREKVVQEKAQLQEqlrALEESLKITKGSLEEEKRraadALKEQQCRATEMEAESRSLMEQREREQ 748
Cdd:pfam02841  159 KLEAKYNQVPRKGVKAEEVLQEFLQSKE---AVEEAILQTDQALTAKEK----AIEAERAKAEAAEAEQELLREKQKEEE 231

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315  749 KELEQEKagrKGLEARIQQLEEAHQAETEALRHELaEATASQHRAESecERLIRevESRQKRFEARQQE 817
Cdd:pfam02841  232 QMMEAQE---RSYQEHVKQLIEKMEAEREQLLAEQ-ERMLEHKLQEQ--EELLK--EGFKTEAESLQKE 292
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1450-1644 1.67e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.53  E-value: 1.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1450 LGERANLGRQFLEVELDQAREKYVQELAavrtDAETHLaemrQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKL 1529
Cdd:COG5022    851 FGRSLKAKKRFSLLKKETIYLQSAQRVE----LAERQL----QELKIDVKSISSLKLVNLELESEIIELKKSLSSDLIEN 922

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1530 TAQVEELSKKLTEHDQASKVQQQKLKAFQaqrgeSQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQ 1609
Cdd:COG5022    923 LEFKTELIARLKKLLNNIDLEEGPSIEYV-----KLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNF 997

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1907176315 1610 NQKLQEQLQDLEELQKENKELRSEAERLGrELQQA 1644
Cdd:COG5022    998 KKELAELSKQYGALQESTKQLKELPVEVA-ELQSA 1031
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1004-1637 1.69e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.67  E-value: 1.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1004 QADLAQEKAAKAELE------MRLQNTLNEQRVEFAALQEALAHALTEKEGTDQEL-AKLRGQEAAQRTELKELQQTLEQ 1076
Cdd:pfam12128  247 QQEFNTLESAELRLShlhfgyKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKrDELNGELSAADAAVAKDRSELEA 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1077 LKIQLVKKEKEHpAGGASGEDASGPGTQSET-------AGKTDAPGPELQALRAEISKLeqqCQQQQQQVEGLTHSLKSE 1149
Cdd:pfam12128  327 LEDQHGAFLDAD-IETAAADQEQLPSWQSELenleerlKALTGKHQDVTAKYNRRRSKI---KEQNNRDIAGIKDKLAKI 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1150 RACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAK----AQDHSKAEEEWKAQVARGQQEAERKSSLISS 1225
Cdd:pfam12128  403 REARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGelklRLNQATATPELLLQLENFDERIERAREEQEA 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1226 LEEEVSILNRQVLEKEGESKELKRlvvAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKqrVVSe 1305
Cdd:pfam12128  483 ANAEVERLQSELRQARKRRDQASE---ALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGK--VIS- 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1306 nsrQELASQAERAEELGQELKAWQEKFFQKEQALSALQLE--HTSTQALVSELLPAKhlcqQLQAEQAAAEKRFREELEQ 1383
Cdd:pfam12128  557 ---PELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPewAASEEELRERLDKAE----EALQSAREKQAAAEEQLVQ 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1384 SKQAAGGLQAELMRAQREL-----------GELGSLRQKIVEQERAAQQLRAEK-ASYAEQLSMLKKAHGLLAEENRG-- 1449
Cdd:pfam12128  630 ANGELEKASREETFARTALknarldlrrlfDEKQSEKDKKNKALAERKDSANERlNSLEAQLKQLDKKHQAWLEEQKEqk 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1450 --LGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEaqsTSRELevmtakyegAKVKVLEER-QRFQEER 1526
Cdd:pfam12128  710 reARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETW---YKRDL---------ASLGVDPDViAKLKREI 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1527 QKLTAQVEELSKKLTEHDQASKVQQ----QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTH 1602
Cdd:pfam12128  778 RTLERKIERIAVRRQEVLRYFDWYQetwlQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVR 857

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1907176315 1603 YDAKKQQNQKLQEQLQDLEELQKENKELRSEAERL 1637
Cdd:pfam12128  858 LSENLRGLRCEMSKLATLKEDANSEQAQGSIGERL 892
PRK11281 PRK11281
mechanosensitive channel MscK;
612-790 1.78e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.75  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  612 ESLQQQLQAANDARD------NAQTSVTQAQ---QEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTT 682
Cdd:PRK11281    39 ADVQAQLDALNKQKLleaedkLVQQDLEQTLallDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETL 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  683 EREKVVQEKAQLQEQLRALEE---------SLKITKGSLEEekrRAADALKEQQCRATE--------------------- 732
Cdd:PRK11281   119 STLSLRQLESRLAQTLDQLQNaqndlaeynSQLVSLQTQPE---RAQAALYANSQRLQQirnllkggkvggkalrpsqrv 195

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315  733 -MEAESRSLMEQREREQKELE-----QE--KAGRKGLEARIQQLEEAHQAETEAL---RHELAEATASQ 790
Cdd:PRK11281   196 lLQAEQALLNAQNDLQRKSLEgntqlQDllQKQRDYLTARIQRLEHQLQLLQEAInskRLTLSEKTVQE 264
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 267-491 1.81e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  267 AASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEH 346
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  347 SKASQEWAEKQARLENELSTAL--------------QDKKCLEEKNEILQGKLSQLEDQATRLQEspapEKGEVLGDALQ 412
Cdd:COG4942     93 AELRAELEAQKEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRA----DLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315  413 LDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 491
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
MreC COG1792
Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome ...
 1601-1662 1.82e-03

Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 441397  Cd Length: 282  Bit Score: 42.56  E-value: 1.82e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176315 1601 THYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLgRELqqagLKTKEAEQTcRHLTAQV 1662
Cdd:COG1792     68 RSLFNLREENERLKEENAELRAELQRLEELEAENARL-REL----LDLKERLDY-KFVAAEV 123
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 609-740 2.06e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 43.40  E-value: 2.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  609 AKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhacieashqeqrqvQARVTELEAQLKAEQQKTTEREKvv 688
Cdd:PRK11448   149 QEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAEL--------------EEKQQELEAQLEQLQEKAAETSQ-- 212

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907176315  689 QEKAQLQEQLRALEESLKITkgslEEEKRRAADalkeQQCRATEMEAESRSL 740
Cdd:PRK11448   213 ERKQKRKEITDQAAKRLELS----EEETRILID----QQLRKAGWEADSKTL 256
PRK06975 PRK06975
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
 1552-1740 2.07e-03

bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed


Pssm-ID: 235899 [Multi-domain]  Cd Length: 656  Bit Score: 43.17  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1552 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQaaehyKLQMEKAKThydakkqqnQKLQEQLQDLeeLQKENKELR 1631
Cdd:PRK06975   357 QRQQANDAQTAELRVKTEQAQASVHQLDSQFAQLDG-----KLADAQSAQ---------QALEQQYQDL--SRNRDDWMI 420

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1632 SEAERLgreLQQAGLKTkeaeqtcrHLTAQVRSLEAQVAHADQQLRDLGKFQVAT---------DALKSrepqvKPQLDL 1702
Cdd:PRK06975   421 AEVEQM---LSSASQQL--------QLTGNVQLALIALQNADARLATSDSPQAVAvrkaiaqdiERLKA-----APSADL 484

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1703 S------------IDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASP 1740
Cdd:PRK06975   485 TglaiklddaiakIDALPLSGEALPPHATMAAAPAAAAAAAAAAAAAGEP 534
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1117-1341 2.17e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1117 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1196
Cdd:COG4942     28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1197 DH----SKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVET 1272
Cdd:COG4942    108 ELlralYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER 187

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315 1273 ASNSARAAERSSALREEVQSLREEvekqrvvsensRQELASQAERAEELGQELKAWQEKFFQKEQALSA 1341
Cdd:COG4942    188 AALEALKAERQKLLARLEKELAEL-----------AAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
412-717 2.20e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.58  E-value: 2.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQaQG 491
Cdd:COG4372     32 QLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE-EA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  492 AQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkeQQLEEAAKEQEAT 571
Cdd:COG4372    111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL----QALSEAEAEQALD 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  572 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHA 651
Cdd:COG4372    187 ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELA 266

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176315  652 CIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKR 717
Cdd:COG4372    267 ILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELAL 332
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 282-655 2.44e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.57  E-value: 2.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  282 KNESLTVRLHETLKQ----CQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQ 357
Cdd:pfam07888   28 RAELLQNRLEECLQEraelLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  358 aRLENELStalQDKKCLEEKNEILQGKLSQLEDQATRLQEspapekgEVLGDALQLDTLKQEAAKLATDNTQLQTRVETL 437
Cdd:pfam07888  108 -ASSEELS---EEKDALLAQRAAHEARIRELEEDIKTLTQ-------RVLERETELERMKERAKKAGAQRKEEEAERKQL 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  438 ECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQgAQLTAQLTSMTGLNATLQQRDQELAS 517
Cdd:pfam07888  177 QAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKE-AENEALLEELRSLQERLNASERKVEG 255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  518 LKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLS-SSLKLKEQQlEEAAKEQEATRQ------DHAQQLAIVAEAREASL 590
Cdd:pfam07888  256 LGEELSSMAAQRDRTQAELHQARLQAAQLTLQLAdASLALREGR-ARWAQERETLQQsaeadkDRIEKLSAELQRLEERL 334

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315  591 RERDTARQQLET-VEKEKDAKLESL---QQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEA 655
Cdd:pfam07888  335 QEERMEREKLEVeLGREKDCNRVQLsesRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLET 403
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 352-863 2.49e-03

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 42.75  E-value: 2.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  352 EWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDqatrLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQ 431
Cdd:pfam05622   11 ELAQRCHELDQQVSLLQEEKNSLQQENKKLQERLDQLES----GDDSGTPGGKKYLLLQKQLEQLQEENFRLETARDDYR 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  432 TRVETLECE----------------------------------RGKQEAQLLAERSRFEDE---KQQLASLIADLQSSVS 474
Cdd:pfam05622   87 IKCEELEKEvlelqhrneeltslaeeaqalkdemdilressdkVKKLEATVETYKKKLEDLgdlRRQVKLLEERNAEYMQ 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  475 NLSQAKEELEQASQAQGaQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQ---AAQGLRQQVEQLS 551
Cdd:pfam05622  167 RTLQLEEELKKANALRG-QLETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKLEALQKEKERliiERDTLRETNEELR 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  552 -SSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 630
Cdd:pfam05622  246 cAQLQQAELSQADALLSPSSDPGDNLAAEIMPAEIREKLIRLQHENKMLRLGQEGSYRERLTELQQLLEDANRRKNELET 325

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  631 SVTQAQQEKAELSQKIGELhacieashQEQRQVQARVTELEAQLKaeqqktterekvvQEKAQLQEQLRALEESLKITKG 710
Cdd:pfam05622  326 QNRLANQRILELQQQVEEL--------QKALQEQGSKAEDSSLLK-------------QKLEEHLEKLHEAQSELQKKKE 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  711 SLEEekrRAADALKEQQCRATEMEAESRS----LMEQREREQKELEQEKAGRKGLEARIQQleeAHQAETEALRHELAEA 786
Cdd:pfam05622  385 QIEE---LEPKQDSNLAQKIDELQEALRKkdedMKAMEERYKKYVEKAKSVIKTLDPKQNP---ASPPEIQALKNQLLEK 458

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315  787 TASQHRAESECE--RLIREVEsrqkrfearqqeearygamfqEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQ 863
Cdd:pfam05622  459 DKKIEHLERDFEksKLQREQE---------------------EKLIVTAWYNMGMALHRKAIEERLAGLSSPGQSFLAR 516
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
576-703 2.52e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 42.34  E-value: 2.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  576 AQQLAIVAEAREASLRERDTARQQLETVEkekdAKLESLQQQLQAANDARDNAQT-----SVTQAQQEKAElsqkigelh 650
Cdd:COG1566     88 AEAQLAAAEAQLARLEAELGAEAEIAAAE----AQLAAAQAQLDLAQRELERYQAlykkgAVSQQELDEAR--------- 154

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176315  651 acieashQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEE 703
Cdd:COG1566    155 -------AALDAAQAQLEAAQAQLAQAQAGLREEEELAAAQAQVAQAEAALAQ 200
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 632-771 2.60e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.89  E-value: 2.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  632 VTQAQQEKAELSQKIGELhacIEASHQEQRQVQARVTELEaQLKAEQQKTteREKVVQEKAQLQEQLRALeeslkitkgs 711
Cdd:PRK00409   504 IEEAKKLIGEDKEKLNEL---IASLEELERELEQKAEEAE-ALLKEAEKL--KEELEEKKEKLQEEEDKL---------- 567

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  712 LEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAgRKGLEARIQQLEEA 771
Cdd:PRK00409   568 LEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYASVKAHELIEA-RKRLNKANEKKEKK 626
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1392-1590 2.66e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 2.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1392 QAELMRAQREL-GELGSLRQKIVEQERAAQQLRA---------EKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFL 1461
Cdd:COG3206    170 REEARKALEFLeEQLPELRKELEEAEAALEEFRQknglvdlseEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1462 EVELDQARE----KYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRF----QEERQKLTAQV 1533
Cdd:COG3206    250 GSGPDALPEllqsPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRIlaslEAELEALQARE 329

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176315 1534 EELSKKLTEHDQASKVQQQKlkafQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAE 1590
Cdd:COG3206    330 ASLQAQLAQLEARLAELPEL----EAELRRLEREVEVARELYESLLQRLEEARLAEA 382
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 621-823 3.10e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  621 ANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQL-KAEQQKTTEREKVVQEKAQLQEQLR 699
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIdKLQAEIAEAEAEIEERREELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  700 AL-EESLKITKGSLEEEKRRAADALKEQQCRATEMEAEsRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEA 778
Cdd:COG3883     94 ALyRSGGSVSYLDVLLGSESFSDFLDRLSALSKIADAD-ADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE 172

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1907176315  779 LRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGA 823
Cdd:COG3883    173 LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 566-771 3.17e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 42.10  E-value: 3.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  566 KEQEATRQDHAQQLAIVAEAREASLRERDTARQQ-LETVEKEKDAKLESLQQQLQAANDARdnaqtsvtQAQQEKAELSQ 644
Cdd:PRK09510    68 QQQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQErLKQLEKERLAAQEQKKQAEEAAKQAA--------LKQKQAEEAAA 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  645 KIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKitKGSLEEEKRRAADALK 724
Cdd:PRK09510   140 KAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKK--KAEAEAKKKAAAEAKK 217

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1907176315  725 EQqcratemEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 771
Cdd:PRK09510   218 KA-------AAEAKAAAAKAAAEAKAAAEKAAAAKAAEKAAAAKAAA 257
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 615-789 3.19e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 42.10  E-value: 3.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  615 QQQLQAanDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQE--QRQVQARVTELEAQLKAEQQKTTEREKVVQE-- 690
Cdd:PRK09510    67 QQQQQK--SAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKErlAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAaa 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  691 -KAQLQEQLRALEESLKITKgslEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE 769
Cdd:PRK09510   145 aKAKAEAEAKRAAAAAKKAA---AEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKKAAA 221

                          170       180
                   ....*....|....*....|
gi 1907176315  770 EAHQAETEALRHELAEATAS 789
Cdd:PRK09510   222 EAKAAAAKAAAEAKAAAEKA 241
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 412-635 3.44e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  412 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQg 491
Cdd:COG3883     38 ELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYLDVLLGSESFSD- 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  492 aqLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 571
Cdd:COG3883    117 --FLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAA 194

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176315  572 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQA 635
Cdd:COG3883    195 EAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAA 258
PRK12704 PRK12704
phosphodiesterase; Provisional
 1503-1653 3.45e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 3.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1503 VMTAKYEGAK---VKVLEERQRFQEE--RQKLTAQVEELSKKLTEHDQASKvqqqklkafqaqrgESQQEVQRLQTQLNE 1577
Cdd:PRK12704    28 IAEAKIKEAEeeaKRILEEAKKEAEAikKEALLEAKEEIHKLRNEFEKELR--------------ERRNELQKLEKRLLQ 93

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176315 1578 LQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEelQKENKELrseaERLgrelqqAGLKTKEAEQ 1653
Cdd:PRK12704    94 KEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELI--EEQLQEL----ERI------SGLTAEEAKE 157
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 584-823 3.81e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  584 EAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQV 663
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  664 QARVTELEAQLKAEQ-----QKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESR 738
Cdd:COG3883     99 GGSVSYLDVLLGSESfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQA 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  739 SLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEE 818
Cdd:COG3883    179 EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAA 258


                   ....*
gi 1907176315  819 ARYGA 823
Cdd:COG3883    259 AGSAG 263
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 456-564 4.04e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 42.25  E-value: 4.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  456 EDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKeqaqmlqtmQE 535
Cdd:PRK11448   141 ENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAE---------TS 211

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1907176315  536 QEQAAQgLRQQVEQLSSSLKLKE--------QQLEEA 564
Cdd:PRK11448   212 QERKQK-RKEITDQAAKRLELSEeetrilidQQLRKA 247
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1261-1584 4.05e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.19  E-value: 4.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1261 LEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSEnSRQELASQAERAEELGQELKAWQEKFFQKEQALS 1340
Cdd:pfam07888   40 LQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAE-LKEELRQSREKHEELEEKYKELSASSEELSEEKD 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1341 ALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAG-------GLQAELMRAQREL----GELGSLR 1409
Cdd:pfam07888  119 ALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKeeeaerkQLQAKLQQTEEELrslsKEFQELR 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1410 QKIVEQERAAQQLRAEKASYAEQLSMLKK---AHGLLAEENRGLGERANLGRQFLEveldqAREKYVQELAAVRTDAETH 1486
Cdd:pfam07888  199 NSLAQRDTQVLQLQDTITTLTQKLTTAHRkeaENEALLEELRSLQERLNASERKVE-----GLGEELSSMAAQRDRTQAE 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1487 LAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELS---KKLTEHDQASKVQQQKLKAFQA---- 1559
Cdd:pfam07888  274 LHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSaelQRLEERLQEERMEREKLEVELGrekd 353

                          330       340
                   ....*....|....*....|....*....
gi 1907176315 1560 ----QRGESQQEVQRLQTQLNELQAQLSQ 1584
Cdd:pfam07888  354 cnrvQLSESRRELQELKASLRVAQKEKEQ 382
mukB PRK04863
chromosome partition protein MukB;
486-823 4.22e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 4.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  486 ASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQT--MQEQEQAAQGLRQQVeqlssslklkeQQLEE 563
Cdd:PRK04863   783 AREKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVafEADPEAELRQLNRRR-----------VELER 851

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  564 AAKEQEATRQDHAQQLaivaeareaslrerDTARQQLETVEK-EKDAKL---ESLQQQLQAANDARDNAQTSVTQAQQEK 639
Cdd:PRK04863   852 ALADHESQEQQQRSQL--------------EQAKEGLSALNRlLPRLNLladETLADRVEEIREQLDEAEEAKRFVQQHG 917

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  640 AELSQkIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKA--------QLQEQLRALEESLKITKGS 711
Cdd:PRK04863   918 NALAQ-LEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAhfsyedaaEMLAKNSDLNEKLRQRLEQ 996

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  712 LEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQ---KELEQEKA-----GRKGLEARIQQLEEAHQAETEALRHEL 783
Cdd:PRK04863   997 AEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRqmlQELKQELQdlgvpADSGAEERARARRDELHARLSANRSRR 1076

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 1907176315  784 AEATASQHRAESECERLIREVESRQKrfEARQQEEARYGA 823
Cdd:PRK04863  1077 NQLEKQLTFCEAEMDNLTKKLRKLER--DYHEMREQVVNA 1114
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1012-1264 4.26e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1012 AAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpag 1091
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE---- 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1092 gasgedasgpgtqsetagkTDAPGPELQALRAEISKL--EQQCQQQQQQVEGLTHSLKSERACRAEQdkALETLQGQLEE 1169
Cdd:COG4942     92 -------------------IAELRAELEAQKEELAELlrALYRLGRQPPLALLLSPEDFLDAVRRLQ--YLKYLAPARRE 150

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1170 KARELGHNQAASASAQRELQALRAKAQdhsKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKR 1249
Cdd:COG4942    151 QAEELRADLAELAALRAELEAERAELE---ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227

                          250
                   ....*....|....*
gi 1907176315 1250 LVVAESEKSQKLEER 1264
Cdd:COG4942    228 LIARLEAEAAAAAER 242
mukB PRK04863
chromosome partition protein MukB;
1273-1668 4.26e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 4.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1273 ASNSARAAERSSALREEVQSLREEVEKqrvvsenSRQELASQAERAEELGQELKAWQEkffqkeqALSALQLEHTST--- 1349
Cdd:PRK04863   271 AADYMRHANERRVHLEEALELRRELYT-------SRRQLAAEQYRLVEMARELAELNE-------AESDLEQDYQAAsdh 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1350 QALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERA--AQQLRAekA 1427
Cdd:PRK04863   337 LNLVQTALRQQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQAldVQQTRA--I 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1428 SYAEQLSMLKKAHGLLaeenrglgeranlgrQFLEVELDQArEKYVQELAAvrtdaethlaemrQEAQSTSRELEvmtak 1507
Cdd:PRK04863   415 QYQQAVQALERAKQLC---------------GLPDLTADNA-EDWLEEFQA-------------KEQEATEELLS----- 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1508 yegakvkvLEERQRFQEERQKLTAQVEELSKKL---TEHDQASKVQQQKLKAFQAQRGESQQeVQRLQTQLNELQaQLSQ 1584
Cdd:PRK04863   461 --------LEQKLSVAQAAHSQFEQAYQLVRKIageVSRSEAWDVARELLRRLREQRHLAEQ-LQQLRMRLSELE-QRLR 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1585 KEQAAEHyklqmekakthydAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRS 1664
Cdd:PRK04863   531 QQQRAER-------------LLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQR 597


                   ....
gi 1907176315 1665 LEAQ 1668
Cdd:PRK04863   598 LAAR 601
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 473-580 4.40e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 41.64  E-value: 4.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  473 VSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASlkeqAKKEQAQMLQTM-QEQEQAAQGLRQQVEQLS 551
Cdd:TIGR04320  249 IPNPPNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAA----AQAALATAQKELaNAQAQALQTAQNNLATAQ 324

                           90       100
                   ....*....|....*....|....*....
gi 1907176315  552 SSLKLKEQQLEEAAKEQEATRQDHAQQLA 580
Cdd:TIGR04320  325 AALANAEARLAKAKEALANLNADLAKKQA 353
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1166-1419 5.24e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 5.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1166 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1245
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1246 ELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRvvseNSRQELASQAERAEELGQEL 1325
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELR----ADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1326 KAWQEKFFQKEQALSALQLEhtstqalvsellpakhlcqqlqaeQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGEL 1405
Cdd:COG4942    177 EALLAELEEERAALEALKAE------------------------RQKLLARLEKELAELAAELAELQQEAEELEALIARL 232

                          250
                   ....*....|....
gi 1907176315 1406 GSLRQKIVEQERAA 1419
Cdd:COG4942    233 EAEAAAAAERTPAA 246
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1574-1699 5.44e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 5.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1574 QLNELQAQLSQKEQAAEhyklqmEKAKTHyDAKKQQNQKLQEQLQD-LEELQKENKELRSEAErlgRELQQAglkTKEAE 1652
Cdd:PRK00409   517 KLNELIASLEELERELE------QKAEEA-EALLKEAEKLKEELEEkKEKLQEEEDKLLEEAE---KEAQQA---IKEAK 583

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 1907176315 1653 QTCRHLTAQVRSLEAQvAHADQQLRDLGKFQVA-TDALKSREPQVKPQ 1699
Cdd:PRK00409   584 KEADEIIKELRQLQKG-GYASVKAHELIEARKRlNKANEKKEKKKKKQ 630
PTZ00491 PTZ00491
major vault protein; Provisional
 601-756 5.52e-03

major vault protein; Provisional


Pssm-ID: 240439 [Multi-domain]  Cd Length: 850  Bit Score: 41.93  E-value: 5.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  601 ETVEKEKDAKLESLQQQLQAANDARDNAQTSvtQAQQEKAELSQkigelhaciEASHQEQRQVqarvteLEAQLKAEQQK 680
Cdd:PTZ00491   636 QSVEPVDERTRDSLQKSVQLAIEITTKSQEA--AARHQAELLEQ---------EARGRLERQK------MHDKAKAEEQR 698

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176315  681 TTEREkVVQEKAQLQEQLRALEESLKITKGSLEEEkrRAADALKEQQCRATEMEAESRSLMEQREREQkELEQEKA 756
Cdd:PTZ00491   699 TKLLE-LQAESAAVESSGQSRAEALAEAEARLIEA--EAEVEQAELRAKALRIEAEAELEKLRKRQEL-ELEYEQA 770
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
1465-1685 5.53e-03

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 41.60  E-value: 5.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1465 LDQAREKYvQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKY---EGAKVKVLEErQRFQEERQKLtAQVEELSKKLT 1541
Cdd:COG0497    153 LEELLEEY-REAYRAWRALKKELEELRADEAERARELDLLRFQLeelEAAALQPGEE-EELEEERRRL-SNAEKLREALQ 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1542 E------------HDQASKVQQ--QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEH---------------- 1591
Cdd:COG0497    230 EalealsggeggaLDLLGQALRalERLAEYDPSLAELAERLESALIELEEAASELRRYLDSLEFdperleeveerlallr 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1592 -----YKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAglktkeaeqtcRHLTAQvrSLE 1666
Cdd:COG0497    310 rlarkYGVTVEELLAYAEELRAELAELENSDERLEELEAELAEAEAELLEAAEKLSAA-----------RKKAAK--KLE 376

                          250       260
                   ....*....|....*....|...
gi 1907176315 1667 AQVAhadQQLRDLG----KFQVA 1685
Cdd:COG0497    377 KAVT---AELADLGmpnaRFEVE 396
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
443-780 5.73e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 5.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  443 KQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQA 522
Cdd:COG4372      3 RLGEKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEEL 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  523 KKEQAQMLQTMQEQEQAaqglRQQVEQLSSSLKLKEQQLEEAAKEQEAtRQDHAQQLAIVAEAREASLRERDTARQQLET 602
Cdd:COG4372     83 EELNEQLQAAQAELAQA----QEELESLQEEAEELQEELEELQKERQD-LEQQRKQLEAQIAELQSEIAEREEELKELEE 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  603 VEKEKDAKLESLQQQLQAANDARDNAQ--TSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQK 680
Cdd:COG4372    158 QLESLQEELAALEQELQALSEAEAEQAldELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSA 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  681 TTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKG 760
Cdd:COG4372    238 LLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDAL 317

                          330       340
                   ....*....|....*....|
gi 1907176315  761 LEARIQQLEEAHQAETEALR 780
Cdd:COG4372    318 LAALLELAKKLELALAILLA 337
PRK01156 PRK01156
chromosome segregation protein; Provisional
 274-816 5.92e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.81  E-value: 5.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  274 SELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSfkvrefaNHLQQLQGAFNDLieehskASQEw 353
Cdd:PRK01156   183 SNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAM-------DDYNNLKSALNEL------SSLE- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  354 aEKQARLENELSTALQDKKCLEEKNEilqgKLSQLEDQATRLQESPAPEKGEVLGDAL----QLDTLKQEAAKLATDNTQ 429
Cdd:PRK01156   249 -DMKNRYESEIKTAESDLSMELEKNN----YYKELEERHMKIINDPVYKNRNYINDYFkyknDIENKKQILSNIDAEINK 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  430 LQTRVETLEcERGKQEAQLLAERSRFEDEKQQLASLIA---DLQSSVSNLSQAKEELEQASQAQ---GAQLTAQLTSMTG 503
Cdd:PRK01156   324 YHAIIKKLS-VLQKDYNDYIKKKSRYDDLNNQILELEGyemDYNSYLKSIESLKKKIEEYSKNIermSAFISEILKIQEI 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  504 LNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLS---------------SSLKLKEQQLEEAAKEQ 568
Cdd:PRK01156   403 DPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNgqsvcpvcgttlgeeKSNHIINHYNEKKSRLE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  569 EATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEkDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAEL-SQKIG 647
Cdd:PRK01156   483 EKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINE-YNKIESARADLEDIKIKINELKDKHDKYEEIKNRYkSLKLE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  648 ELhaciEASHQEQRQVQARVTELEaqLKAEQQKTTEREKVVQEkaqLQEQLRALEESLKITKGSLEEEKRRAADALKEQQ 727
Cdd:PRK01156   562 DL----DSKRTSWLNALAVISLID--IETNRSRSNEIKKQLND---LESRLQEIEIGFPDDKSYIDKSIREIENEANNLN 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  728 CRATEMEAESRsLMEQREREQKELEQEKAGRKGLEARIQQLE-EAHQAETE--ALRHELAEATASQHRAESECERLIREV 804
Cdd:PRK01156   633 NKYNEIQENKI-LIEKLRGKIDNYKKQIAEIDSIIPDLKEITsRINDIEDNlkKSRKALDDAKANRARLESTIEILRTRI 711

                          570
                   ....*....|..
gi 1907176315  805 ESRQKRFEARQQ 816
Cdd:PRK01156   712 NELSDRINDINE 723
46 PHA02562
endonuclease subunit; Provisional
 1524-1690 6.46e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.54  E-value: 6.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1524 EERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQ---------AQLSQKEQAAEHYKL 1594
Cdd:PHA02562   227 EEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEkggvcptctQQISEGPDRITKIKD 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1595 QMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ 1674
Cdd:PHA02562   307 KLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386

                          170       180
                   ....*....|....*....|....*..
gi 1907176315 1675 QLRDLGK-----------FQVATDALK 1690
Cdd:PHA02562   387 ELDKIVKtkselvkekyhRGIVTDLLK 413
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 180-707 6.96e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 6.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  180 LEIQRIASSSSENNFLSGSPSSPMGDILQTPQFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAmmQQRIDHL 259
Cdd:pfam15921  278 VEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELE--KQLVLAN 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  260 ALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQcqnLKTEKSQMDR----------KISQLSEENGDLSFKVREFA 329
Cdd:pfam15921  356 SELTEARTERDQFSQESGNLDDQLQKLLADLHKREKE---LSLEKEQNKRlwdrdtgnsiTIDHLRRELDDRNMEVQRLE 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  330 NHLQQLQGAFNDLIEEHSKASQ---EWAEKQARLENEL-STALQDKKCLEE---KNEILQGKLSQLEDQATRLQESP--- 399
Cdd:pfam15921  433 ALLKAMKSECQGQMERQMAAIQgknESLEKVSSLTAQLeSTKEMLRKVVEEltaKKMTLESSERTVSDLTASLQEKErai 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  400 APEKGEVLGDALQLDTLKQEAAKLATDNTQL---QTRVETLECERGKQEAQLLAERSRFED-----------------EK 459
Cdd:pfam15921  513 EATNAEITKLRSRVDLKLQELQHLKNEGDHLrnvQTECEALKLQMAEKDKVIEILRQQIENmtqlvgqhgrtagamqvEK 592

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  460 QQLASLIADLQSSVSNLSQAKEEleqaSQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQA 539
Cdd:pfam15921  593 AQLEKEINDRRLELQEFKILKDK----KDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNE 668

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  540 AQGLRQQVEQLSSSLKLKEQQLEEAA---KEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQ 616
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEMETTTnklKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQS 748

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  617 QLQAANDARDNAQTSVTQAQQEKAELSQKIG-------ELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQ 689
Cdd:pfam15921  749 KIQFLEEAMTNANKEKHFLKEEKNKLSQELStvateknKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828

                          570
                   ....*....|....*...
gi 1907176315  690 EKAQLQEQLRaLEESLKI 707
Cdd:pfam15921  829 RQEQESVRLK-LQHTLDV 845
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1391-1643 7.36e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.57  E-value: 7.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1391 LQAELMRAQRELGELGSLRQKIvEQERAAQQLRAEKASYAEQLSMLKKAhgllAEENRGLGERANLGRQFLEVELDQARE 1470
Cdd:TIGR00606  797 FQMELKDVERKIAQQAAKLQGS-DLDRTVQQVNQEKQEKQHELDTVVSK----IELNRKLIQDQQEQIQHLKSKTNELKS 871

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1471 KYVQ--ELAAVRTDAETHLAEMRQEAQSTSRELEvmTAKYEGAKVKVLEERqrFQEERQKLTAQVEELSKKLTEHDQASK 1548
Cdd:TIGR00606  872 EKLQigTNLQRRQQFEEQLVELSTEVQSLIREIK--DAKEQDSPLETFLEK--DQQEKEELISSKETSNKKAQDKVNDIK 947

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1549 VQQQKLKAFQA------QRGESQQEVQRlQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQdLEE 1622
Cdd:TIGR00606  948 EKVKNIHGYMKdienkiQDGKDDYLKQK-ETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLT-LRK 1025

                          250       260
                   ....*....|....*....|.
gi 1907176315 1623 LQKENKELRSEAERLGRELQQ 1643
Cdd:TIGR00606 1026 RENELKEVEEELKQHLKEMGQ 1046
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 636-918 7.42e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 7.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  636 QQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQE-KAQLQEQLRALEESLKITKgsLEE 714
Cdd:pfam17380  302 RQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEeRKRELERIRQEEIAMEISR--MRE 379

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  715 EKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQ----EKAGRKGLEAR---IQQLEEAHQAETEALRHELAEAT 787
Cdd:pfam17380  380 LERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQkvemEQIRAEQEEARqreVRRLEEERAREMERVRLEEQERQ 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  788 ASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHAS 867
Cdd:pfam17380  460 QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAE 539

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907176315  868 LAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQE 918
Cdd:pfam17380  540 EERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAE 590
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 588-892 7.78e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 41.17  E-value: 7.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  588 ASLRERDTArQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQV--QA 665
Cdd:pfam05667  206 PSLLERNAA-ELAAAQEWEEEWNSQGLASRLTPEEYRKRKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAELlsSF 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  666 RVTELEAQLKAEQQKTTEREKVvqekaQLQEQLRALEESLKITKGSLEEekrraadaLKEQQcratemEAESRSLMEQRE 745
Cdd:pfam05667  285 SGSSTTDTGLTKGSRFTHTEKL-----QFTNEAPAATSSPPTKVETEEE--------LQQQR------EEELEELQEQLE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  746 REQKELEQEKAGRKGLEARIQQLEEaHQAETEALRHELAEATASQHR-------AESECERLIREVESRQKRFE--ARQQ 816
Cdd:pfam05667  346 DLESSIQELEKEIKKLESSIKQVEE-ELEELKEQNEELEKQYKVKKKtldllpdAEENIAKLQALVDASAQRLVelAGQW 424

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176315  817 EEARygAMFQEQLMALKGEKTGQEVQEEaveihsegqpgQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSAL 892
Cdd:pfam05667  425 EKHR--VPLIEEYRALKEAKSNKEDESQ-----------RKLEEIKELREKIKEVAEEAKQKEELYKQLVAEYERL 487
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1417-1680 7.96e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.48  E-value: 7.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1417 RAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERanlgRQFLEVELDQAREKYVQELAAVRtdaethLAEMRQEAQS 1496
Cdd:COG3096    285 ERALELRRELFGARRQLAEEQYRLVEMARELEELSAR----ESDLEQDYQAASDHLNLVQTALR------QQEKIERYQE 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1497 TSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQK----------------------- 1553
Cdd:COG3096    355 DLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRaiqyqqavqalekaralcglpdl 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1554 --------LKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKL---QMEKAKTHYDAKK------------QQN 1610
Cdd:COG3096    435 tpenaedyLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKiagEVERSQAWQTAREllrryrsqqalaQRL 514

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1611 QKLQEQLQDLEELQKENKELRSEAERLGrelQQAGLKTKEAEQtcrhLTAQVRSLEAQVAHADQQLRDLG 1680
Cdd:COG3096    515 QQLRAQLAELEQRLRQQQNAERLLEEFC---QRIGQQLDAAEE----LEELLAELEAQLEELEEQAAEAV 577
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 682-804 8.28e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.22  E-value: 8.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  682 TEREKVVQEKAQLQEQLRALEeslkITKGSLEEEKRRAADAlkeqqcRATEMEAESRSLMEQREREQKELEQEKAGRKGL 761
Cdd:COG0542    404 MEIDSKPEELDELERRLEQLE----IEKEALKKEQDEASFE------RLAELRDELAELEEELEALKARWEAEKELIEEI 473

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1907176315  762 EARIQQLEEAHQaETEALRHELAEATAsqhrAESECERLIREV 804
Cdd:COG0542    474 QELKEELEQRYG-KIPELEKELAELEE----ELAELAPLLREE 511
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
426-572 8.68e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 40.80  E-value: 8.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  426 DNTQLQTRVETLECERGKQEAQLLAERSRfEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQltsmtgln 505
Cdd:COG1566     77 DPTDLQAALAQAEAQLAAAEAQLARLEAE-LGAEAEIAAAEAQLAAAQAQLDLAQRELERYQALYKKGAVSQ-------- 147

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176315  506 atlqqrdQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQ--QVEQLSSSLKLKEQQLEEAAKEQEATR 572
Cdd:COG1566    148 -------QELDEARAALDAAQAQLEAAQAQLAQAQAGLREeeELAAAQAQVAQAEAALAQAELNLARTT 209
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1499-1643 8.86e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 40.39  E-value: 8.86e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  1499 RELEVMTAKYEgakvKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQK----LKAFQAQRGESQQEVQRLQTQ 1574
Cdd:smart00787  151 ENLEGLKEDYK----LLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCdpteLDRAKEKLKKLLQEIMIKVKK 226

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  1575 LNELQAQLSQKEQAAEhyklqmekakthydAKKQQNQKLQEQLQDLEELQKENKEL-RSEAERLGRELQQ 1643
Cdd:smart00787  227 LEELEEELQELESKIE--------------DLTNKKSELNTEIAEAEKKLEQCRGFtFKEIEKLKEQLKL 282
PRK11281 PRK11281
mechanosensitive channel MscK;
1034-1343 8.93e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.44  E-value: 8.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1034 ALQEALAHALTEKEGTDQ--ELAKLRGQEAAQRTELKELQQTLEQL-KIQLVKKEKEHPAGGASGEDASgpgTQSETAGK 1110
Cdd:PRK11281    27 ARAASNGDLPTEADVQAQldALNKQKLLEAEDKLVQQDLEQTLALLdKIDRQKEETEQLKQQLAQAPAK---LRQAQAEL 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1111 TDAPGPELQALRAEISKLEqqCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEkarelghNQAASASAQRELQA 1190
Cdd:PRK11281   104 EALKDDNDEETRETLSTLS--LRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPER-------AQAALYANSQRLQQ 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1191 LRAKAQDhSKAEEEWKAQVARGQQEAErksslISSLEEEVSiLNRQVLEKEGESKELKRLVVAE-SEKSQKLEERLRLLQ 1269
Cdd:PRK11281   175 IRNLLKG-GKVGGKALRPSQRVLLQAE-----QALLNAQND-LQRKSLEGNTQLQDLLQKQRDYlTARIQRLEHQLQLLQ 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1270 veTASNSARAAErSSALREEVQSLREEVEKQR---VVSENSR-----QELASQAERAEELGQE---LKAWQEKFFQKEQA 1338
Cdd:PRK11281   248 --EAINSKRLTL-SEKTVQEAQSQDEAARIQAnplVAQELEInlqlsQRLLKATEKLNTLTQQnlrVKNWLDRLTQSERN 324


                   ....*....
gi 1907176315 1339 L----SALQ 1343
Cdd:PRK11281   325 IkeqiSVLK 333
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1517-1751 9.04e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 9.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1517 EERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNElQAQLSQKEQAAEHYKLQM 1596
Cdd:COG3883     30 AELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE-RARALYRSGGSVSYLDVL 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1597 EKAKTHYDA----------KKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLE 1666
Cdd:COG3883    109 LGSESFSDFldrlsalskiADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLS 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1667 AQVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASPISQRLP 1746
Cdd:COG3883    189 AEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAGAAGAA 268


                   ....*
gi 1907176315 1747 PKVES 1751
Cdd:COG3883    269 AGAAG 273
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 597-785 9.10e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.19  E-value: 9.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  597 RQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEK----------AELSQKIGELHA---------CIEASH 657
Cdd:PRK10929    29 TQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQqvidnfpklsAELRQQLNNERDeprsvppnmSTDALE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  658 QEQRQVQARVTELEAQLKAEQQKTTE-REKVVQEKAQLQEQLRALEE------SLKITKGSLEEEKRRAADA-LKEQQCR 729
Cdd:PRK10929   109 QEILQVSSQLLEKSRQAQQEQDRAREiSDSLSQLPQQQTEARRQLNEierrlqTLGTPNTPLAQAQLTALQAeSAALKAL 188

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176315  730 ATEMEAESRSLMEQRE--REQKELEQEKAGRkgLEARIQ----QLEEAHQAETE-ALRH--ELAE 785
Cdd:PRK10929   189 VDELELAQLSANNRQElaRLRSELAKKRSQQ--LDAYLQalrnQLNSQRQREAErALESteLLAE 251
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
596-848 9.30e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 9.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  596 ARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLK 675
Cdd:COG4372     11 ARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQ 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  676 AEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEK 755
Cdd:COG4372     91 AAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  756 AGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGE 835
Cdd:COG4372    171 QELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEE 250

                          250
                   ....*....|...
gi 1907176315  836 KTGQEVQEEAVEI 848
Cdd:COG4372    251 LLEEVILKEIEEL 263
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1004-1311 9.33e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 9.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1004 QADLAQEKAAKA-ELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLV 1082
Cdd:pfam17380  298 QERLRQEKEEKArEVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRM 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1083 KKEKEhpaggasgedasgpgTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALEt 1162
Cdd:pfam17380  378 RELER---------------LQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLE- 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1163 lqgqlEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEW-KAQVARGQQEAERKSSLISSLEEEVSIL-----NRQ 1236
Cdd:pfam17380  442 -----EERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELeKEKRDRKRAEEQRRKILEKELEERKQAMieeerKRK 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1237 VLEKEGESK-------ELKRLVVAESEKSQKLEERLRLLQVETASNSARAaeRSSALREEVQSLREEVEkqrvvSENSRQ 1309
Cdd:pfam17380  517 LLEKEMEERqkaiyeeERRREAEEERRKQQEMEERRRIQEQMRKATEERS--RLEAMEREREMMRQIVE-----SEKARA 589


                   ..
gi 1907176315 1310 EL 1311
Cdd:pfam17380  590 EY 591
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 298-549 9.42e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.09  E-value: 9.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  298 QNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQ---GAFNDLIEEHSkasqewAEKQARLENELSTALQDKKCL 374
Cdd:COG3096    839 AALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNkllPQANLLADETL------ADRLEELREELDAAQEAQAFI 912

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  375 EEKNEilqgKLSQLEDQATRLQESPAPE---KGEVLGDALQLDTLKQ------------------EAAKLATDNT----Q 429
Cdd:COG3096    913 QQHGK----ALAQLEPLVAVLQSDPEQFeqlQADYLQAKEQQRRLKQqifalsevvqrrphfsyeDAVGLLGENSdlneK 988

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315  430 LQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQ--ASQAQGAQLTAQlTSMTGLNAT 507
Cdd:COG3096    989 LRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEElgVQADAEAEERAR-IRRDELHEE 1067

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1907176315  508 LQQRDQELASLKEQ---AKKEQAQMLQTMQEQEQAAQGLRQQVEQ 549
Cdd:COG3096   1068 LSQNRSRRSQLEKQltrCEAEMDSLQKRLRKAERDYKQEREQVVQ 1112
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1520-1602 9.79e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.09  E-value: 9.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176315 1520 QRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQK--EQAAEHYKLQME 1597
Cdd:PRK11448   145 HALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETsqERKQKRKEITDQ 224


                   ....*
gi 1907176315 1598 KAKTH 1602
Cdd:PRK11448   225 AAKRL 229
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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