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Conserved domains on  [gi|1907176327|ref|XP_036008437|]
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nuclear mitotic apparatus protein 1 isoform X5 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 462-1231 1.05e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 119.78  E-value: 1.05e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  462 LKLKEQQlEEAAKEQEATRQDHAQQLAIVAEAREA--SL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 538
Cdd:TIGR02168  168 SKYKERR-KETERKLERTRENLDRLEDILNELERQlkSLeRQAEKAERYKELKAELRELELALLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  539 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLkaeQQKTTEREKVVQEKAQLQEQLRALEESLKITKG 618
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL---YALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  619 SLEEEKRRaadaLKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHqaetEALRHELAEATASQ 698
Cdd:TIGR02168  324 QLEELESK----LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----ETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  699 HRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 778
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  779 AIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASlELLKEPPRAANRASDQLGEQQGRPFSST 858
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAAIEAALGGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  859 -HAAVKAMEREAEQMGG-----ELERLRAALIKSQGQQQEERGQQEREVA-RLTQERGQAQADL---------------A 916
Cdd:TIGR02168  555 lNAAKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAkDLVKFDPKLRKALsyllggvlvvddldnA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  917 QEKAAKAELEMRLQnTLNEQRVE---FAALQEALAHALTekEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKE 993
Cdd:TIGR02168  635 LELAKKLRPGYRIV-TLDGDLVRpggVITGGSAKTNSSI--LERRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  994 KEHPAGGASGEDASgpGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQG 1073
Cdd:TIGR02168  712 EELEQLRKELEELS--RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1074 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1153
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1154 ELKRLVVAESEKSQKLEERLRLL--QVETASNSARAAE-RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELG 1230
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY 949


                   .
gi 1907176327 1231 Q 1231
Cdd:TIGR02168  950 S 950
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1774-1832 7.34e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


:

Pssm-ID: 412093  Cd Length: 56  Bit Score: 101.91  E-value: 7.34e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327 1774 LLSLPGYRPTTRSSARRSQarmSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1832
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1025-1560 7.15e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.86  E-value: 7.15e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1025 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1104
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1105 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVA-ESEKSQKLEERLRLLQ--VETA 1181
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEaEEELEELAEELLEALRaaAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1182 SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1261
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1262 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL--------------MRAQRELGELGSLRQKIVEQERAA 1327
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavavligveaaYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1328 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRTDAETHLAEMRQE 1401
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRR 638

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1402 AQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqrEQTKQVEELSKKLTEHDQASKVQQQKLKAFQA 1481
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE----ELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327 1482 QRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKthydakkqqnqklQEQLQDLEELQKENKELRSEAERLG 1560
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE-------------LPEPPDLEELERELERLEREIEALG 780
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 121-722 8.44e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.93  E-value: 8.44e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  121 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALlnekqaassqepsELEELRGKNESLTVRLHE 200
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  201 TLKQCQNLKTEKSQMDRKISQLSEENgdlsfkvrefanhlqqlqgafndlieehskasQEWAEKQARLENELSTALQDKK 280
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEEL--------------------------------AELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  281 CLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLEcergKQEAQLLAER 360
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  361 SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQT 440
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  441 MQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLE 520
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  521 SLQ-QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashqeqrqVQARVTELEAQLKAEQQKTTEREKVVQEK 599
Cdd:COG1196    584 ARAaLAAALARGAIGAAVDLVASDLREADARYYVLGDTLL-----------GRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  600 AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 679
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907176327  680 HQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEAR 722
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
HkD_SF super family cl41774
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ...
 1-59 6.12e-14

Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.


The actual alignment was detected with superfamily member cd22224:

Pssm-ID: 425405  Cd Length: 148  Bit Score: 71.06  E-value: 6.12e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327    1 MELAKMIMLFLYQSTMSSRNlrDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFL 59
Cdd:cd22224     91 LELAKVLLLLLYHSMMNNNL--TLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
PRK06975 super family cl35524
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
 1474-1662 3.18e-03

bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed


The actual alignment was detected with superfamily member PRK06975:

Pssm-ID: 235899 [Multi-domain]  Cd Length: 656  Bit Score: 42.40  E-value: 3.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1474 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQaaehyKLQMEKAKThydakkqqnQKLQEQLQDLeeLQKENKELR 1553
Cdd:PRK06975   357 QRQQANDAQTAELRVKTEQAQASVHQLDSQFAQLDG-----KLADAQSAQ---------QALEQQYQDL--SRNRDDWMI 420

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1554 SEAERLgreLQQAGLKTkeaeqtcrHLTAQVRSLEAQVAHADQQLRDLGKFQVAT---------DALKSrepqvKPQLDL 1624
Cdd:PRK06975   421 AEVEQM---LSSASQQL--------QLTGNVQLALIALQNADARLATSDSPQAVAvrkaiaqdiERLKA-----APSADL 484

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1625 S------------IDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASP 1662
Cdd:PRK06975   485 TglaiklddaiakIDALPLSGEALPPHATMAAAPAAAAAAAAAAAAAGEP 534
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 462-1231 1.05e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 119.78  E-value: 1.05e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  462 LKLKEQQlEEAAKEQEATRQDHAQQLAIVAEAREA--SL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 538
Cdd:TIGR02168  168 SKYKERR-KETERKLERTRENLDRLEDILNELERQlkSLeRQAEKAERYKELKAELRELELALLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  539 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLkaeQQKTTEREKVVQEKAQLQEQLRALEESLKITKG 618
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL---YALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  619 SLEEEKRRaadaLKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHqaetEALRHELAEATASQ 698
Cdd:TIGR02168  324 QLEELESK----LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----ETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  699 HRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 778
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  779 AIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASlELLKEPPRAANRASDQLGEQQGRPFSST 858
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAAIEAALGGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  859 -HAAVKAMEREAEQMGG-----ELERLRAALIKSQGQQQEERGQQEREVA-RLTQERGQAQADL---------------A 916
Cdd:TIGR02168  555 lNAAKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAkDLVKFDPKLRKALsyllggvlvvddldnA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  917 QEKAAKAELEMRLQnTLNEQRVE---FAALQEALAHALTekEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKE 993
Cdd:TIGR02168  635 LELAKKLRPGYRIV-TLDGDLVRpggVITGGSAKTNSSI--LERRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  994 KEHPAGGASGEDASgpGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQG 1073
Cdd:TIGR02168  712 EELEQLRKELEELS--RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1074 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1153
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1154 ELKRLVVAESEKSQKLEERLRLL--QVETASNSARAAE-RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELG 1230
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY 949


                   .
gi 1907176327 1231 Q 1231
Cdd:TIGR02168  950 S 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 423-998 4.72e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 117.35  E-value: 4.72e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  423 LASLKEQAKK-EQAQMLQTmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEqeatrqdhaqqlaivAEAREASLRER 501
Cdd:COG1196    202 LEPLERQAEKaERYRELKE-ELKELEAELLLLKLRELEAELEELEAELEELEAE---------------LEELEAELAEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  502 DTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQ 581
Cdd:COG1196    266 EAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  582 LKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQ 661
Cdd:COG1196    346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  662 EKAGRKGLEARIQQLEEA----------HQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGA 731
Cdd:COG1196    426 LEEALAELEEEEEEEEEAleeaaeeeaeLEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  732 MFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGqqqsqlAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNkev 811
Cdd:COG1196    506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE------AALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF--- 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  812 acLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSThAAVKAMEREAEQMGGELERLRAALIKSQGQQQ 891
Cdd:COG1196    577 --LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVTLEG 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  892 EERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQ 971
Cdd:COG1196    654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          570       580
                   ....*....|....*....|....*..
gi 1907176327  972 RTELKELQQTLEQLKIQLVKKEKEHPA 998
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPP 760
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1774-1832 7.34e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 101.91  E-value: 7.34e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327 1774 LLSLPGYRPTTRSSARRSQarmSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1832
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1025-1560 7.15e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.86  E-value: 7.15e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1025 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1104
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1105 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVA-ESEKSQKLEERLRLLQ--VETA 1181
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEaEEELEELAEELLEALRaaAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1182 SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1261
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1262 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL--------------MRAQRELGELGSLRQKIVEQERAA 1327
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavavligveaaYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1328 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRTDAETHLAEMRQE 1401
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRR 638

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1402 AQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqrEQTKQVEELSKKLTEHDQASKVQQQKLKAFQA 1481
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE----ELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327 1482 QRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKthydakkqqnqklQEQLQDLEELQKENKELRSEAERLG 1560
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE-------------LPEPPDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 121-722 8.44e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.93  E-value: 8.44e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  121 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALlnekqaassqepsELEELRGKNESLTVRLHE 200
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  201 TLKQCQNLKTEKSQMDRKISQLSEENgdlsfkvrefanhlqqlqgafndlieehskasQEWAEKQARLENELSTALQDKK 280
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEEL--------------------------------AELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  281 CLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLEcergKQEAQLLAER 360
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  361 SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQT 440
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  441 MQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLE 520
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  521 SLQ-QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashqeqrqVQARVTELEAQLKAEQQKTTEREKVVQEK 599
Cdd:COG1196    584 ARAaLAAALARGAIGAAVDLVASDLREADARYYVLGDTLL-----------GRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  600 AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 679
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907176327  680 HQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEAR 722
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
PTZ00121 PTZ00121
MAEBL; Provisional
 173-845 1.03e-19

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 97.13  E-value: 1.03e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  173 KQAASSQEPSELEELRGKNESLTV----RLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAfn 248
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAeavkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-- 1280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  249 dliEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKlSQLEDQATRLQEspAPEKGEVLGDALQLDTLKQEA 328
Cdd:PTZ00121  1281 ---DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK-KKAEEAKKKADA--AKKKAEEAKKAAEAAKAEAEA 1354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  329 AKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTS 408
Cdd:PTZ00121  1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  409 MTGLNATLQQRDQELASLKEQAKKeqAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLA 488
Cdd:PTZ00121  1435 EAKKKAEEAKKADEAKKKAEEAKK--AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA 1512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  489 ivAEAREAS-LRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQE 567
Cdd:PTZ00121  1513 --DEAKKAEeAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  568 QRQVQA--RVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKgslEEEKRRAADALKEQQCRATEMEAES 645
Cdd:PTZ00121  1591 EARIEEvmKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE---AEEKKKAEELKKAEEENKIKAAEEA 1667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  646 RSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQE 725
Cdd:PTZ00121  1668 KKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAE 1747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  726 EARYGAMFQEQLMALKG--EKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEK 803
Cdd:PTZ00121  1748 EAKKDEEEKKKIAHLKKeeEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEM 1827

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|..
gi 1907176327  804 MAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASD 845
Cdd:PTZ00121  1828 EDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEAD 1869
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 911-1603 8.23e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.97  E-value: 8.23e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  911 AQADLAQEKAAKAELEMRLqNTLNEQR---VEFAALQEALAHA-----LTEKEGTDQELAKLRGQEAAQRTELKELQQTL 982
Cdd:TIGR02168  184 TRENLDRLEDILNELERQL-KSLERQAekaERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  983 EQLKIQLVKKEKEHPAGGASGEDASGpgtqsetagktdapgpELQALRAEISKLEQQCQQQQQQVEGLTHSLKseracra 1062
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQK----------------ELYALANEISRLEQQKQILRERLANLERQLE------- 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1063 EQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILN 1142
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1143 rqvlekegeskelKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQ 1222
Cdd:TIGR02168  400 -------------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1223 AERAEELGQELKAWQEKFFQKEQ---ALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKrFREELEQSKQAAGG- 1298
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALGg 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1299 -LQAELMR------------AQRELG-------------ELGSLRQKIVEQERAAQQLRAEKASYAEQLSM--------- 1343
Cdd:TIGR02168  546 rLQAVVVEnlnaakkaiaflKQNELGrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggv 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1344 -----LKKAHGLLAEENRGL-------------------GERANLGRQFLEVELDQAREKY------VQELAAVRTDAET 1393
Cdd:TIGR02168  626 lvvddLDNALELAKKLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIeeleekIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1394 HLAEMRQEAQSTSRELEVMTAKYEGAKvkvlEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQ 1473
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALR----KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1474 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELR 1553
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176327 1554 SEAERLGRELQ---QAGLKTKEAEQTCRH--------LTAQVRSLEAQVAHADQQLRDLGK 1603
Cdd:TIGR02168  862 EELEELIEELEselEALLNERASLEEALAllrseleeLSEELRELESKRSELRRELEELRE 922
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 119-752 2.15e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.15e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  119 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPS--------ELEELRGK 190
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELEsrleeleeQLETLRSK 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  191 NESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANH------------LQQLQGAFNDLIEEHSKAS 258
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelqaeleeleeeLEELQEELERLEEALEELR 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  259 QEWAEKQARL---ENELSTALQDKKCLEEKNEILQG----------KLSQLEDQATRLQESPAPEKG------EVLGDAL 319
Cdd:TIGR02168  468 EELEEAEQALdaaERELAQLQARLDSLERLQENLEGfsegvkallkNQSGLSGILGVLSELISVDEGyeaaieAALGGRL 547

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  320 Q-------------LDTLKQEAAKLATD---NTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSN 383
Cdd:TIGR02168  548 QavvvenlnaakkaIAFLKQNELGRVTFlplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  384 LSQAKEELEQASQAQGAQLTAQLT--------SMTG----LNATLQQRDQELASLKEQakkeQAQMLQTMQEQEQAAQGL 451
Cdd:TIGR02168  628 VDDLDNALELAKKLRPGYRIVTLDgdlvrpggVITGgsakTNSSILERRREIEELEEK----IEELEEKIAELEKALAEL 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  452 RQQVEQLSSSLKLKEQQLEEAAKEQEATRQDhAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND 531
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  532 ARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQ-----------QKTTEREKVVQEKA 600
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATErrledleeqieELSEDIESLAAEIE 862

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  601 QLQEQLRALE---ESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE 677
Cdd:TIGR02168  863 ELEELIEELEselEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  678 EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRF--------EARQQEEARYGAMFQEQLMALKGEKTGQEV 749
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022


                   ...
gi 1907176327  750 QEE 752
Cdd:TIGR02168 1023 IEE 1025
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 1-59 6.12e-14

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 71.06  E-value: 6.12e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327    1 MELAKMIMLFLYQSTMSSRNlrDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFL 59
Cdd:cd22224     91 LELAKVLLLLLYHSMMNNNL--TLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
151-658 2.24e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 72.38  E-value: 2.24e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  151 TEKDAQIAMMQQRIDHlALLNEKQAASSQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS 220
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  221 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQ 290
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  291 GKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQL 370
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  371 ASLIADLQSSVSNLSQAKEELEQA--------------------SQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQA 430
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAGkcpecgqpvegsphvetieeDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  431 K-----KEQAQMLQ--------TMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaiVAEAREAS 497
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEARE--------EVAELNSK 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  498 LRERDTARQQLETVEkEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACI-EASHQEQRQVQARVT 576
Cdd:PRK02224   581 LAELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFdEARIEEAREDKERAE 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  577 ELEAQLKAE-QQKTTEREKVVQEKAQLQEQLRALEEsLKITKGSLeEEKRRAADALKEQQCRATEMEAESRSLMEQRERE 655
Cdd:PRK02224   660 EYLEQVEEKlDELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLRAELRQRNVE 737


                   ...
gi 1907176327  656 QKE 658
Cdd:PRK02224   738 TLE 740
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 358-556 8.60e-12

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 71.02  E-value: 8.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  358 AERSRFEDEKQQLASLIADLQSSVSNLSQAKeeLEQASQAQGAQL-------TAQLTSMT-GLNAtLQQRDQELASLKEQ 429
Cdd:NF012221  1569 ADRQRLEQEKQQQLAAISGSQSQLESTDQNA--LETNGQAQRDAIleesravTKELTTLAqGLDA-LDSQATYAGESGDQ 1645

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  430 AKKEQAQ-MLQTMQEQ-EQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQ-----QLAIVAEAREASLRERD 502
Cdd:NF012221  1646 WRNPFAGgLLDRVQEQlDDAKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQnqanaEQDIDDAKADAEKRKDD 1725

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907176327  503 TARQQLETVEKEKDAKLESLQQQLQAANDARdNAQTSVTQAQQEKAELSQKIGE 556
Cdd:NF012221  1726 ALAKQNEAQQAESDANAAANDAQSRGEQDAS-AAENKANQAQADAKGAKQDESD 1778
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 289-868 3.47e-11

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 68.71  E-value: 3.47e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  289 LQGKLSQLEDQATRLQESpapeKGEVLGDALQLDTLKQEAA--------KLATDNTQLQTRVETLECERGKQEAQLLAER 360
Cdd:pfam12128  246 LQQEFNTLESAELRLSHL----HFGYKSDETLIASRQEERQetsaelnqLLRTLDDQWKEKRDELNGELSAADAAVAKDR 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  361 SRFED-EKQQLASLIADLQSSVSNLSQA---KEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQ 436
Cdd:pfam12128  322 SELEAlEDQHGAFLDADIETAAADQEQLpswQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAK 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  437 MLQTMQEQEQAAQG--------LRQQVEQLSSSLKLKEQQLEEAAKEqEATRQDHAQQLAIVAEAREASLRERDTARQQL 508
Cdd:pfam12128  402 IREARDRQLAVAEDdlqaleseLREQLEAGKLEFNEEEYRLKSRLGE-LKLRLNQATATPELLLQLENFDERIERAREEQ 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  509 EtvekEKDAKLESLQQQLQAANDARDNA-------QTSVTQAQQEKAELSQ----KIGELHACIEASHQEQRQVQARVTE 577
Cdd:pfam12128  481 E----AANAEVERLQSELRQARKRRDQAsealrqaSRRLEERQSALDELELqlfpQAGTLLHFLRKEAPDWEQSIGKVIS 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  578 LEAQLKAEQQKTTEREKVVQEKAQLQEQLRaLEESLKITKGSLEEEKRRAADALKE----QQCRATEMEAESRSLMEQRE 653
Cdd:pfam12128  557 PELLHRTDLDPEVWDGSVGGELNLYGVKLD-LKRIDVPEWAASEEELRERLDKAEEalqsAREKQAAAEEQLVQANGELE 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  654 REQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAM- 732
Cdd:pfam12128  636 KASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTe 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  733 FQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVA 812
Cdd:pfam12128  716 KQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVL 795

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327  813 CLKTLvlkageQQETASLE--LLKEPPRAANRASDQLGEQQGRPFSSTHAAVKAMERE 868
Cdd:pfam12128  796 RYFDW------YQETWLQRrpRLATQLSNIERAISELQQQLARLIADTKLRRAKLEME 847
PTZ00121 PTZ00121
MAEBL; Provisional
 1052-1575 2.41e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.32  E-value: 2.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1052 HSLKSERACRAEQDKALETLQGQLEEKARElgHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLI 1131
Cdd:PTZ00121  1056 HEGKAEAKAHVGQDEGLKPSYKDFDFDAKE--DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA 1133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1132 SSLEEEVSIlnrqvlEKEGESKELKRLVVA-ESEKSQKLEERLRLLQVETASNSARAAERSSAlrEEVQSLRE--EVEKQ 1208
Cdd:PTZ00121  1134 RKAEDARKA------EEARKAEDAKRVEIArKAEDARKAEEARKAEDAKKAEAARKAEEVRKA--EELRKAEDarKAEAA 1205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1209 RVVSENSRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcQQLQAEQAAAEKRFREE 1288
Cdd:PTZ00121  1206 RKAEEERKAEEARKAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF--ARRQAAIKAEEARKADE 1282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1289 LEQSKQAAgglQAELMRAQRELGELGSLRQKiVEQERAAQQLRAEKASYAEQLSMLKKAhgllAEENRGLGERAnlgrqf 1368
Cdd:PTZ00121  1283 LKKAEEKK---KADEAKKAEEKKKADEAKKK-AEEAKKADEAKKKAEEAKKKADAAKKK----AEEAKKAAEAA------ 1348

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1369 leveldqarekyvqelaavrtdaethlaemRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKltaqveqlevfq 1448
Cdd:PTZ00121  1349 ------------------------------KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK------------ 1386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1449 REQTKQVEELSKKLTEHDQasKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAK 1528
Cdd:PTZ00121  1387 AEEKKKADEAKKKAEEDKK--KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1529 KQQNQKLQEQLQDLEELQKENKELRSEAERLGR---ELQQAGLKTKEAEQ 1575
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKkadEAKKAAEAKKKADE 1514
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1110-1603 1.62e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 59.74  E-value: 1.62e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1110 EEEWKAQVARGQQEAERKSSlissleEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAE 1189
Cdd:pfam05483  103 QKENKLQENRKIIEAQRKAI------QELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEY 176

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1190 RSSALREEVQSLREEVEKQ-------RVVSENSRQELASQAERAEELGQEL-KAWQEKFFQKEQALSALQLEHTSTQALV 1261
Cdd:pfam05483  177 EREETRQVYMDLNNNIEKMilafeelRVQAENARLEMHFKLKEDHEKIQHLeEEYKKEINDKEKQVSLLLIQITEKENKM 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1262 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL----MRAQRELGELGSLRQKIVEQERAAQQLRAEKASY 1337
Cdd:pfam05483  257 KDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELedikMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQ 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1338 AEQLSMLKKAHGLLAEENRG----LGERANLGRQFLEVELDQarekyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMT 1413
Cdd:pfam05483  337 MEELNKAKAAHSFVVTEFEAttcsLEELLRTEQQRLEKNEDQ-----LKIITMELQKKSSELEEMTKFKNNKEVELEELK 411

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1414 aKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRL 1493
Cdd:pfam05483  412 -KILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIEL 490

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1494 QTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQkenKELRSEAERLGRELQQAGLKTK-- 1571
Cdd:pfam05483  491 TAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKE---MNLRDELESVREEFIQKGDEVKck 567

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1907176327 1572 --EAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1603
Cdd:pfam05483  568 ldKSEENARSIEYEVLKKEKQMKILENKCNNLKK 601
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 160-725 1.55e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 56.72  E-value: 1.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  160 MQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS----QLSEENGDLSFKVRE 235
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAarkqELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  236 FANHLQQLQGafndlieEHSKASQEWAEKQARLENELSTALQ---DKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKG 312
Cdd:pfam01576   87 EEERSQQLQN-------EKKKMQQHIQDLEEQLDEEEAARQKlqlEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  313 EVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQllaeRSRFEDEKQQLASLIADLQSSVSNLSQAKEELE 392
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG----RQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  393 QASQAQGAQLTAQLTSM---TGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkEQQL 469
Cdd:pfam01576  236 AQLAKKEEELQAALARLeeeTAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL---EDTL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  470 EEAAKEQEAtrqdHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 549
Cdd:pfam01576  313 DTTAAQQEL----RSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  550 LSQKIGELHACIEASHQEQRQVQARVTELEAQL-KAEQQKTTEREKVVQEKAQLQEQLRALEE----SLKITK--GSLEE 622
Cdd:pfam01576  389 LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLsESERQRAELAEKLSKLQSELESVSSLLNEaegkNIKLSKdvSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  623 EKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLeeahQAETEALRHELAEATASQHRAE 702
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTL----QAQLSDMKKKLEEDAGTLEALE 544

                          570       580
                   ....*....|....*....|...
gi 1907176327  703 SECERLIREVESRQKRFEARQQE 725
Cdd:pfam01576  545 EGKKRLQRELEALTQQLEEKAAA 567
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 411-527 1.33e-05

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 48.35  E-value: 1.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  411 GLNATLQQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGlRQQVEQLSSSLKLKEQQLEEAAKEQEaTRQDHAQQLAIV 490
Cdd:NF038305    98 HLNNTRRLSTQALQQINQQAGQQETQ-LQQQLNQLQAQTS-PQQLNQLLKSEQKQGQALASGQLPEE-QKEQLQQFKSNP 174

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1907176327  491 AEAREASLRERDTARQQLETVEKEkdAKLESLQQQLQ 527
Cdd:NF038305   175 QALDKFLAQQLTQIRTQAEEAEKQ--ARLEALKSSLR 209
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 485-862 4.29e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.06  E-value: 4.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  485 QQLAIVAEAREASLRERDTARQQ-LETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGElhaciea 563
Cdd:NF012221  1503 KTLKLTAKAGSNRLEFKGTGHNDgLGYILDNVVATSESSQQADAVSKHAKQDDAAQNALADKERAEADRQRLE------- 1575

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  564 shQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGsleeekrraADALKEQQCRATEMEA 643
Cdd:NF012221  1576 --QEKQQQLAAISGSQSQLESTDQNALETNGQAQRDAILEESRAVTKELTTLAQG---------LDALDSQATYAGESGD 1644

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  644 ESRSLMEQR--EREQKELEQEKagrKGLEARIQQLEEAHQAETEALRHELAEATASQHRAesecERLIREVESRQKrfEA 721
Cdd:NF012221  1645 QWRNPFAGGllDRVQEQLDDAK---KISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQG----EQNQANAEQDID--DA 1715

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  722 RQQEEARYGAMFQEQLMALKGEKTGQEVQEEAveihseGQPGQQQSQLAQLHASLAKAiqqvqekevraqklvDDLSALQ 801
Cdd:NF012221  1716 KADAEKRKDDALAKQNEAQQAESDANAAANDA------QSRGEQDASAAENKANQAQA---------------DAKGAKQ 1774

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176327  802 EKMAATNKEVACLKTLVLKAGEQQETA--SLELLKEPPRAAN-RASDQLGEQQGRPFSSTHAAV 862
Cdd:NF012221  1775 DESDKPNRQGAAGSGLSGKAYSVEGVAepGSHINPDSPAAADgRFSEGLTEQEQEALEGATNAV 1838
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 758-1028 9.48e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 9.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  758 SEGQpgQQQSQLAQlHASLAKAIQQVQEKEVRA-----------QKLVDDLSALQEKMAATNKEVACLKTLVLKAG--EQ 824
Cdd:NF012221  1538 SESS--QQADAVSK-HAKQDDAAQNALADKERAeadrqrleqekQQQLAAISGSQSQLESTDQNALETNGQAQRDAilEE 1614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  825 QETASLELLKEPPR-AANRASDQLGEQQGRPFSsTHAAVKAMEREAEQM-------GGELERLRAALIKSQGQQQEERGQ 896
Cdd:NF012221  1615 SRAVTKELTTLAQGlDALDSQATYAGESGDQWR-NPFAGGLLDRVQEQLddakkisGKQLADAKQRHVDNQQKVKDAVAK 1693

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  897 QEREVARLTQERGQAQADLAQekaAKAELEMRLQNTLNEQRVefAALQEALAHALTEKegtdqelAKLRGQEAAQRTELK 976
Cdd:NF012221  1694 SEAGVAQGEQNQANAEQDIDD---AKADAEKRKDDALAKQNE--AQQAESDANAAAND-------AQSRGEQDASAAENK 1761

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176327  977 ELQQTLEQLKIQLVKKEKEHPAgGASGEDASGPGTQSETAGKTD-APGPELQA 1028
Cdd:NF012221  1762 ANQAQADAKGAKQDESDKPNRQ-GAAGSGLSGKAYSVEGVAEPGsHINPDSPA 1813
TOPEUc smart00435
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ...
 1517-1600 1.62e-03

DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras


Pssm-ID: 214661 [Multi-domain]  Cd Length: 391  Bit Score: 43.11  E-value: 1.62e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  1517 QMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ 1596
Cdd:smart00435  278 SMEKLQEKIKALKYQLKRLKKMILLFEMISDLKRKLKSKFERDNEKLDAEVKEKKKEKKKEEKKKKQIERLEERIEKLEV 357


                    ....
gi 1907176327  1597 QLRD 1600
Cdd:smart00435  358 QATD 361
PRK06975 PRK06975
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
 1474-1662 3.18e-03

bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed


Pssm-ID: 235899 [Multi-domain]  Cd Length: 656  Bit Score: 42.40  E-value: 3.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1474 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQaaehyKLQMEKAKThydakkqqnQKLQEQLQDLeeLQKENKELR 1553
Cdd:PRK06975   357 QRQQANDAQTAELRVKTEQAQASVHQLDSQFAQLDG-----KLADAQSAQ---------QALEQQYQDL--SRNRDDWMI 420

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1554 SEAERLgreLQQAGLKTkeaeqtcrHLTAQVRSLEAQVAHADQQLRDLGKFQVAT---------DALKSrepqvKPQLDL 1624
Cdd:PRK06975   421 AEVEQM---LSSASQQL--------QLTGNVQLALIALQNADARLATSDSPQAVAvrkaiaqdiERLKA-----APSADL 484

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1625 S------------IDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASP 1662
Cdd:PRK06975   485 TglaiklddaiakIDALPLSGEALPPHATMAAAPAAAAAAAAAAAAAGEP 534
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 462-1231 1.05e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 119.78  E-value: 1.05e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  462 LKLKEQQlEEAAKEQEATRQDHAQQLAIVAEAREA--SL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 538
Cdd:TIGR02168  168 SKYKERR-KETERKLERTRENLDRLEDILNELERQlkSLeRQAEKAERYKELKAELRELELALLVLRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  539 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLkaeQQKTTEREKVVQEKAQLQEQLRALEESLKITKG 618
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL---YALANEISRLEQQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  619 SLEEEKRRaadaLKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHqaetEALRHELAEATASQ 698
Cdd:TIGR02168  324 QLEELESK----LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----ETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  699 HRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 778
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  779 AIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASlELLKEPPRAANRASDQLGEQQGRPFSST 858
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAAIEAALGGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  859 -HAAVKAMEREAEQMGG-----ELERLRAALIKSQGQQQEERGQQEREVA-RLTQERGQAQADL---------------A 916
Cdd:TIGR02168  555 lNAAKKAIAFLKQNELGrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAkDLVKFDPKLRKALsyllggvlvvddldnA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  917 QEKAAKAELEMRLQnTLNEQRVE---FAALQEALAHALTekEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKE 993
Cdd:TIGR02168  635 LELAKKLRPGYRIV-TLDGDLVRpggVITGGSAKTNSSI--LERRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  994 KEHPAGGASGEDASgpGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQG 1073
Cdd:TIGR02168  712 EELEQLRKELEELS--RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1074 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1153
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1154 ELKRLVVAESEKSQKLEERLRLL--QVETASNSARAAE-RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELG 1230
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY 949


                   .
gi 1907176327 1231 Q 1231
Cdd:TIGR02168  950 S 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 423-998 4.72e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 117.35  E-value: 4.72e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  423 LASLKEQAKK-EQAQMLQTmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEqeatrqdhaqqlaivAEAREASLRER 501
Cdd:COG1196    202 LEPLERQAEKaERYRELKE-ELKELEAELLLLKLRELEAELEELEAELEELEAE---------------LEELEAELAEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  502 DTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQ 581
Cdd:COG1196    266 EAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  582 LKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQ 661
Cdd:COG1196    346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  662 EKAGRKGLEARIQQLEEA----------HQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGA 731
Cdd:COG1196    426 LEEALAELEEEEEEEEEAleeaaeeeaeLEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  732 MFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGqqqsqlAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNkev 811
Cdd:COG1196    506 FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE------AALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF--- 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  812 acLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSThAAVKAMEREAEQMGGELERLRAALIKSQGQQQ 891
Cdd:COG1196    577 --LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAALRRAVTLAGRLREVTLEG 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  892 EERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQ 971
Cdd:COG1196    654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          570       580
                   ....*....|....*....|....*..
gi 1907176327  972 RTELKELQQTLEQLKIQLVKKEKEHPA 998
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPP 760
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1774-1832 7.34e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 101.91  E-value: 7.34e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327 1774 LLSLPGYRPTTRSSARRSQarmSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1832
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 461-1232 7.59e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.61  E-value: 7.59e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  461 SLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSV 540
Cdd:TIGR02168  204 SLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEI 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  541 TQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREK----VVQEKAQLQEQLRALEESLKIT 616
Cdd:TIGR02168  284 EELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEelaeLEEKLEELKEELESLEAELEEL 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  617 KGSLEEEKRRAAD---ALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE-EAHQAETEALRHELA 692
Cdd:TIGR02168  364 EAELEELESRLEEleeQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLkKLEEAELKELQAELE 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  693 EATASQHRAESECERLIREVESRQKRFEARQQEEARygamFQEQLMALKGEKTGQEVQEEAVEIHSEG--QPGQQQSQLA 770
Cdd:TIGR02168  444 ELEEELEELQEELERLEEALEELREELEEAEQALDA----AERELAQLQARLDSLERLQENLEGFSEGvkALLKNQSGLS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  771 QLHASLAKAIqQVQEKEVRAqkLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQ 850
Cdd:TIGR02168  520 GILGVLSELI-SVDEGYEAA--IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  851 QGRPFSSTHAAVKAMEREAEQMGGELERLR--------AALIKSQGQQQEERGQQEREVAR-------------LTQERG 909
Cdd:TIGR02168  597 IEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvddldnaLELAKKLRPGYRIVTLDGDLVRPggvitggsaktnsSILERR 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  910 QAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQL 989
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  990 VKKEKEHPA-----GGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQ 1064
Cdd:TIGR02168  757 TELEAEIEEleerlEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1065 DKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQ 1144
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRE 916

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1145 VLEKEGESKELK----RLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELA 1220
Cdd:TIGR02168  917 LEELREKLAQLElrleGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYE 996

                          810
                   ....*....|..
gi 1907176327 1221 SQAERAEELGQE 1232
Cdd:TIGR02168  997 ELKERYDFLTAQ 1008
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 320-873 1.14e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 109.64  E-value: 1.14e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  320 QLDTLKQEAAKlATDNTQLQTRVETLECE-RGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQ 398
Cdd:COG1196    201 QLEPLERQAEK-AERYRELKEELKELEAElLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  399 GAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSsLKLKEQQLEEAAKEQEA 478
Cdd:COG1196    280 ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE-LEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  479 TRQDHAQQLAIVAEAREASLRERDTARQQLETVEK---EKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIG 555
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRaaaELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  556 ELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALK--- 632
Cdd:COG1196    439 EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLlag 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  633 ------------------EQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEA 694
Cdd:COG1196    519 lrglagavavligveaayEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIG 598

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  695 TA-SQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLH 773
Cdd:COG1196    599 AAvDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  774 ASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGR 853
Cdd:COG1196    679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPE 758

                          570       580
                   ....*....|....*....|..
gi 1907176327  854 PFSSTHAA--VKAMEREAEQMG 873
Cdd:COG1196    759 PPDLEELEreLERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 238-778 6.29e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 106.94  E-value: 6.29e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  238 NHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGD 317
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  318 ALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQA 397
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  398 QgAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQE 477
Cdd:COG1196    395 A-AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  478 ATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQ---AANDARDNAQTSVTQAQQEKAELSQKI 554
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgavAVLIGVEAAYEAALEAALAAALQNIVV 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  555 GELHACIEASHQEQRQVQARVTEL--EAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALK 632
Cdd:COG1196    554 EDDEVAAAAIEYLKAAKAGRATFLplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  633 EQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQhRAESECERLIREV 712
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL-LAEEEEERELAEA 712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176327  713 ESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAK 778
Cdd:COG1196    713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 386-985 1.08e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 106.17  E-value: 1.08e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  386 QAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMlqtmQEQEQAAQGLRQQVEQLSSSLKLK 465
Cdd:COG1196    211 KAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAEL----AELEAELEELRLELEELELELEEA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  466 EQQLEEAAKEQEATRQD--HAQQLAIVAEAREASL-RERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQ 542
Cdd:COG1196    287 QAEEYELLAELARLEQDiaRLEERRRELEERLEELeEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  543 AQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEE 622
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  623 EKRRAADALKEqqcratemEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAhQAETEALRHELAEATASQHRAE 702
Cdd:COG1196    447 AAEEEAELEEE--------EEALLELLAELLEEAALLEAALAELLEELAEAAARLLL-LLEAEADYEGFLEGVKAALLLA 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  703 SECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALkgektgQEVQEEAVEIHSEGQPGQQQ-SQLAQLHASLAKAIQ 781
Cdd:COG1196    518 GLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED------DEVAAAAIEYLKAAKAGRATfLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  782 QVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEppRAANRASDQLGEQQGrpfSSTHAA 861
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR--LREVTLEGEGGSAGG---SLTGGS 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  862 VKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFA 941
Cdd:COG1196    667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1907176327  942 ALQEALAHALTEKEgtdqelaklrgQEAAQRTELKELQQTLEQL 985
Cdd:COG1196    747 LLEEEALEELPEPP-----------DLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 115-815 5.11e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 104.37  E-value: 5.11e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  115 LQTPQFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRI-DHLALLNEKQAASSQEPSELEELRGKNES 193
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyALANEISRLEQQKQILRERLANLERQLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  194 LTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAE---KQARLEN 270
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQlelQIASLNN 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  271 ELSTALQDKKCLEEKNEILQGKLSQLEDQatrlqespaPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERG 350
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKK---------LEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  351 KQEAQLLAERSRFEDEKQQLASL-----------------------IADLQSSVSNLSQAKEELEQA-SQAQGAQLTAQL 406
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLerlqenlegfsegvkallknqsgLSGILGVLSELISVDEGYEAAiEAALGGRLQAVV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  407 TSmtglnaTLQQRDQELASLKeQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQ 486
Cdd:TIGR02168  552 VE------NLNAAKKAIAFLK-QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGG 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  487 LAIVAEAREA-SLRERDTARQQLETVEKEKDAKLESLqqqlqaaNDARDNAQTSVTQAQQEKAELSQKIGELhacieash 565
Cdd:TIGR02168  625 VLVVDDLDNAlELAKKLRPGYRIVTLDGDLVRPGGVI-------TGGSAKTNSSILERRREIEELEEKIEEL-------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  566 qeqrqvQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAES 645
Cdd:TIGR02168  690 ------EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  646 RSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETE---ALRHELAEATASQHRAESECERLIREVESRQKRFEAR 722
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  723 QQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEgQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQE 802
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLN-ERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          730
                   ....*....|...
gi 1907176327  803 KMAATNKEVACLK 815
Cdd:TIGR02168  923 KLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 183-978 6.42e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 103.98  E-value: 6.42e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  183 ELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKvrefanhLQQLQGAFNDLIEEHSKASQEWA 262
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE-------IEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  263 EKQARLENelstALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRV 342
Cdd:TIGR02168  306 ILRERLAN----LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  343 ETLECERGKQEAQLLAERSRFedekQQLASLIADLQSSVSNLSQAKEELEQasQAQGAQLTAQLTSMTGLNATLQQRDQE 422
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNEI----ERLEARLERLEDRRERLQQEIEELLK--KLEEAELKELQAELEELEEELEELQEE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  423 LASLKEQAKKEQAQMlqtmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaiVAEAREASLRERD 502
Cdd:TIGR02168  456 LERLEEALEELREEL----EEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKA--------LLKNQSGLSGILG 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  503 TARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKA-------ELS----QKIGELHACIEASHQEQRQV 571
Cdd:TIGR02168  524 VLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNElgrvtflPLDsikgTEIQGNDREILKNIEGFLGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  572 QARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKI--------TKGSLEEEKRRAADALkeQQCRATEMEa 643
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIvtldgdlvRPGGVITGGSAKTNSS--ILERRREIE- 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  644 ESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQ 723
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  724 QEEARYGAMFQEQLMALKGEKTGQEVQEEAVEihsegqpgQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEK 803
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIE--------QLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  804 MAATNKEVACLKTLVLKAGEQQETASLEL--LKEPPRAANRASDQLGEQqgrpFSSTHAAVKAMEREAEQMGGELERLRa 881
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIeeLEELIEELESELEALLNE----RASLEEALALLRSELEELSEELRELE- 907

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  882 aliksqgqqqeergqqeREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEalaHALTEKEGTDQEL 961
Cdd:TIGR02168  908 -----------------SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE---EAEALENKIEDDE 967

                          810
                   ....*....|....*..
gi 1907176327  962 AKLRGQEAAQRTELKEL 978
Cdd:TIGR02168  968 EEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1025-1560 7.15e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.86  E-value: 7.15e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1025 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1104
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1105 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVA-ESEKSQKLEERLRLLQ--VETA 1181
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEaEEELEELAEELLEALRaaAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1182 SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1261
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1262 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL--------------MRAQRELGELGSLRQKIVEQERAA 1327
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavavligveaaYEAALEAALAAALQNIVVEDDEVA 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1328 QQ----LRAEKASYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRTDAETHLAEMRQE 1401
Cdd:COG1196    560 AAaieyLKAAKAGRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRR 638

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1402 AQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqrEQTKQVEELSKKLTEHDQASKVQQQKLKAFQA 1481
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE----ELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327 1482 QRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKthydakkqqnqklQEQLQDLEELQKENKELRSEAERLG 1560
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE-------------LPEPPDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1025-1544 5.48e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 100.78  E-value: 5.48e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1025 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1104
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1105 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNS 1184
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1185 ARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1264
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1265 LPAKHLcqQLQAEQAAAEKRFREELEQSKQAAGGLQAEL-----MRAQRELGELGSLRQKIVEQERAAQQ----LRAEKA 1335
Cdd:COG1196    494 LLLLEA--EADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaaYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKA 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1336 SYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELD---QAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELE 1410
Cdd:COG1196    572 GRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADaryYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1411 VMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEV 1490
Cdd:COG1196    652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327 1491 QRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTH------------------------YDAKKQQNQKLQEQLQDLEE 1544
Cdd:COG1196    732 AEREELLEELLEEEELLEEEALEELPEPPDLEELerelerlereiealgpvnllaieeYEELEERYDFLSEQREDLEE 809
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 121-811 2.52e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.98  E-value: 2.52e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  121 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHL-----ALLNEKQAASSQE---PSELEELRGKNE 192
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkelyALANEISRLEQQKqilRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  193 SLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAE---KQARLE 269
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQlelQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  270 NELSTALQDKKCLEEKNEILQGKLSQLEDQatrlqespaPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECER 349
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKK---------LEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  350 GKQEAQLLAERSRFEDEKQQLASL-----------------------IADLQSSVSNLSQAKEELEQA-SQAQGAQLTAQ 405
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLerlqenlegfsegvkallknqsgLSGILGVLSELISVDEGYEAAiEAALGGRLQAV 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  406 LtsMTGLNATLQ--------------------QRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKL- 464
Cdd:TIGR02168  551 V--VENLNAAKKaiaflkqnelgrvtflpldsIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVv 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  465 ------KEQQLEEAAKEQEATRQDH--AQQLAIVAEAREASL------RERDTARQQLETVE---KEKDAKLESLQQQLQ 527
Cdd:TIGR02168  629 ddldnaLELAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSsilerrREIEELEEKIEELEekiAELEKALAELRKELE 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  528 AANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTE-----------REKVV 596
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeelaeaeaeIEELE 788

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  597 QEKAQLQEQLRALEESLKITKGSLEEEKRRAADA----------LKEQQCRATEMEAESRSLMEQREREQKELEQEKAGR 666
Cdd:TIGR02168  789 AQIEQLKEELKALREALDELRAELTLLNEEAANLrerleslerrIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  667 KGLEARIQQLEE---AHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMAL--K 741
Cdd:TIGR02168  869 EELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLseE 948

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  742 GEKTGQEVQEEAVEIhsEGQPGQQQSQLAQLHASLAK-------AIQQVQEKEVR-----AQK--LVDDLSALQEKMAAT 807
Cdd:TIGR02168  949 YSLTLEEAEALENKI--EDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELKERydfltAQKedLTEAKETLEEAIEEI 1026


                   ....
gi 1907176327  808 NKEV 811
Cdd:TIGR02168 1027 DREA 1030
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1027-1603 7.49e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.93  E-value: 7.49e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1027 QALRAEISKLEqqcqqqqqqVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDH 1106
Cdd:COG1196    216 RELKEELKELE---------AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1107 SKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSAR 1186
Cdd:COG1196    287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1187 AAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP 1266
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1267 AKHLCQQLQAEQAAAEKRFREELEQSKQAagglQAELMRAQRELGELGSlRQKIVEQERAAQQLRAEKASYAEQLSMLKK 1346
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALL----EAALAELLEELAEAAA-RLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1347 AHGLLAEENRG-------LGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGA 1419
Cdd:COG1196    522 LAGAVAVLIGVeaayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1420 KVKVLEERqrfqEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNE 1499
Cdd:COG1196    602 DLVASDLR----EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1500 LQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRH 1579
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570       580
                   ....*....|....*....|....
gi 1907176327 1580 LTAQVRSLEAQVAHADQQLRDLGK 1603
Cdd:COG1196    758 EPPDLEELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 121-722 8.44e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.93  E-value: 8.44e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  121 QMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALlnekqaassqepsELEELRGKNESLTVRLHE 200
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  201 TLKQCQNLKTEKSQMDRKISQLSEENgdlsfkvrefanhlqqlqgafndlieehskasQEWAEKQARLENELSTALQDKK 280
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEEL--------------------------------AELEEELEELEEELEELEEELE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  281 CLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLEcergKQEAQLLAER 360
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  361 SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQT 440
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  441 MQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLE 520
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  521 SLQ-QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashqeqrqVQARVTELEAQLKAEQQKTTEREKVVQEK 599
Cdd:COG1196    584 ARAaLAAALARGAIGAAVDLVASDLREADARYYVLGDTLL-----------GRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  600 AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 679
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907176327  680 HQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEAR 722
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
PTZ00121 PTZ00121
MAEBL; Provisional
 173-845 1.03e-19

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 97.13  E-value: 1.03e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  173 KQAASSQEPSELEELRGKNESLTV----RLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAfn 248
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAeavkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-- 1280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  249 dliEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKlSQLEDQATRLQEspAPEKGEVLGDALQLDTLKQEA 328
Cdd:PTZ00121  1281 ---DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK-KKAEEAKKKADA--AKKKAEEAKKAAEAAKAEAEA 1354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  329 AKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTS 408
Cdd:PTZ00121  1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  409 MTGLNATLQQRDQELASLKEQAKKeqAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLA 488
Cdd:PTZ00121  1435 EAKKKAEEAKKADEAKKKAEEAKK--AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA 1512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  489 ivAEAREAS-LRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQE 567
Cdd:PTZ00121  1513 --DEAKKAEeAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  568 QRQVQA--RVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKgslEEEKRRAADALKEQQCRATEMEAES 645
Cdd:PTZ00121  1591 EARIEEvmKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE---AEEKKKAEELKKAEEENKIKAAEEA 1667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  646 RSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQE 725
Cdd:PTZ00121  1668 KKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAE 1747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  726 EARYGAMFQEQLMALKG--EKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEK 803
Cdd:PTZ00121  1748 EAKKDEEEKKKIAHLKKeeEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEM 1827

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|..
gi 1907176327  804 MAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASD 845
Cdd:PTZ00121  1828 EDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEAD 1869
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 782-1544 5.04e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 94.74  E-value: 5.04e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  782 QVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLvLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSThAA 861
Cdd:TIGR02168  219 KAELRELELALLVLRLEELREELEELQEELKEAEEE-LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA-NE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  862 VKAMEREAEQMGGELERLRAaliksqgqqqeERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFA 941
Cdd:TIGR02168  297 ISRLEQQKQILRERLANLER-----------QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  942 ALQEALAHALTEKEGTDQ---ELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGK 1018
Cdd:TIGR02168  366 ELEELESRLEELEEQLETlrsKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1019 TDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDkALETLQGQLEEKARELghnqAASASAQRELQA 1098
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD-SLERLQENLEGFSEGV----KALLKNQSGLSG 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1099 LRAKAQDHSKAEEEWKA------------------QVARGQQEAERKSSLI-SSLEEEVSILNRQVLEKEGESKELKRLV 1159
Cdd:TIGR02168  521 ILGVLSELISVDEGYEAaieaalggrlqavvvenlNAAKKAIAFLKQNELGrVTFLPLDSIKGTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1160 VAESEKSQKLEERLRLL------QVETASNSARAAERSSALREE---VQSLREEVEKQRVVSENSRQELASQAERA---E 1227
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKAlsyllgGVLVVDDLDNALELAKKLRPGyriVTLDGDLVRPGGVITGGSAKTNSSILERRreiE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1228 ELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQ 1307
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1308 RE----LGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQe 1383
Cdd:TIGR02168  761 AEieelEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR- 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1384 laavRTDAETHLAEMRQEAQSTSRELEVMTakyegakvkvlEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLT 1463
Cdd:TIGR02168  840 ----LEDLEEQIEELSEDIESLAAEIEELE-----------ELIEELESELEALLNERASLEEALALLRSELEELSEELR 904

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1464 EHDqaskvqqQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQ-KEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDL 1542
Cdd:TIGR02168  905 ELE-------SKRSELRRELEELREKLAQLELRLEGLEVRIDNlQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRL 977


                   ..
gi 1907176327 1543 EE 1544
Cdd:TIGR02168  978 EN 979
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 911-1603 8.23e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.97  E-value: 8.23e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  911 AQADLAQEKAAKAELEMRLqNTLNEQR---VEFAALQEALAHA-----LTEKEGTDQELAKLRGQEAAQRTELKELQQTL 982
Cdd:TIGR02168  184 TRENLDRLEDILNELERQL-KSLERQAekaERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  983 EQLKIQLVKKEKEHPAGGASGEDASGpgtqsetagktdapgpELQALRAEISKLEQQCQQQQQQVEGLTHSLKseracra 1062
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQK----------------ELYALANEISRLEQQKQILRERLANLERQLE------- 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1063 EQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILN 1142
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1143 rqvlekegeskelKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQ 1222
Cdd:TIGR02168  400 -------------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1223 AERAEELGQELKAWQEKFFQKEQ---ALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKrFREELEQSKQAAGG- 1298
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALGg 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1299 -LQAELMR------------AQRELG-------------ELGSLRQKIVEQERAAQQLRAEKASYAEQLSM--------- 1343
Cdd:TIGR02168  546 rLQAVVVEnlnaakkaiaflKQNELGrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggv 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1344 -----LKKAHGLLAEENRGL-------------------GERANLGRQFLEVELDQAREKY------VQELAAVRTDAET 1393
Cdd:TIGR02168  626 lvvddLDNALELAKKLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIeeleekIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1394 HLAEMRQEAQSTSRELEVMTAKYEGAKvkvlEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQ 1473
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALR----KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1474 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELR 1553
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176327 1554 SEAERLGRELQ---QAGLKTKEAEQTCRH--------LTAQVRSLEAQVAHADQQLRDLGK 1603
Cdd:TIGR02168  862 EELEELIEELEselEALLNERASLEEALAllrseleeLSEELRELESKRSELRRELEELRE 922
PTZ00121 PTZ00121
MAEBL; Provisional
 867-1574 1.04e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 93.67  E-value: 1.04e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  867 REAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTlneQRVEFAALQEA 946
Cdd:PTZ00121  1104 KKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEA---RKAEDAKKAEA 1180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  947 LAHALTEKEGTDQELAK-LRGQEAAQRTE----LKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDA 1021
Cdd:PTZ00121  1181 ARKAEEVRKAEELRKAEdARKAEAARKAEeerkAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEA 1260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1022 PGPELQALRAEISKLEQQCQQQQQQVEgltHSLKSERACRAEQDKALETLQGQLEEKaRELGHNQAASASAQRELQALRA 1101
Cdd:PTZ00121  1261 RMAHFARRQAAIKAEEARKADELKKAE---EKKKADEAKKAEEKKKADEAKKKAEEA-KKADEAKKKAEEAKKKADAAKK 1336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1102 KAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvAESEKSQKLEERLRLLQVETA 1181
Cdd:PTZ00121  1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK---ADEAKKKAEEDKKKADELKKA 1413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1182 SNSARAAERSSALREEVQSLREEVEKQrvvsensrqELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALV 1261
Cdd:PTZ00121  1414 AAAKKKADEAKKKAEEKKKADEAKKKA---------EEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK 1484

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1262 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRElgelgslRQKIVEQERAAQQLRAEKASYAEQL 1341
Cdd:PTZ00121  1485 ADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEE-------AKKADEAKKAEEKKKADELKKAEEL 1557

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1342 SmlKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDAETHLAEMRQEAqstsrelevmtakyEGAKV 1421
Cdd:PTZ00121  1558 K--KAEEKKKAEEAKKAEEDKNMALRKAE-EAKKAEEARIEEVMKLYEEEKKMKAEEAKKA--------------EEAKI 1620

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1422 KVlEERQRFQEERQKltaqVEQLEVFQREQTKQVEELSKKltEHDQASKVQQQKLKAFQAQRgesqqevqrlqtQLNELQ 1501
Cdd:PTZ00121  1621 KA-EELKKAEEEKKK----VEQLKKKEAEEKKKAEELKKA--EEENKIKAAEEAKKAEEDKK------------KAEEAK 1681

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907176327 1502 AQLSQKEQAAEHYKLQMEKAKTHYDAKKqqnqKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAE 1574
Cdd:PTZ00121  1682 KAEEDEKKAAEALKKEAEEAKKAEELKK----KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750
PTZ00121 PTZ00121
MAEBL; Provisional
 561-1340 2.05e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 92.90  E-value: 2.05e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  561 IEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEE------KRRAADALKEQ 634
Cdd:PTZ00121  1052 IDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEArkaeeaKKKAEDARKAE 1131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  635 QCRATEmeaESRSLMEQREREqkELEQEKAGRKGLEARiqQLEEAHQAEtEALRHELAEATASQHRAESecerlIREVES 714
Cdd:PTZ00121  1132 EARKAE---DARKAEEARKAE--DAKRVEIARKAEDAR--KAEEARKAE-DAKKAEAARKAEEVRKAEE-----LRKAED 1198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  715 RQKRFEARQQEEARYGAMFQEQLMALKGE--KTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQK 792
Cdd:PTZ00121  1199 ARKAEAARKAEEERKAEEARKAEDAKKAEavKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEAR 1278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  793 LVDDLSALQEKMAATNKEvaclktlvlKAGEQQETASLELLKEPPRAANRASDQLGEQQGRpfssthaaVKAMEREAEQM 872
Cdd:PTZ00121  1279 KADELKKAEEKKKADEAK---------KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKK--------ADAAKKKAEEA 1341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  873 GGELERLRAAliKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAkaelEMRLQNTLNEQRVEFAALQEALAHALT 952
Cdd:PTZ00121  1342 KKAAEAAKAE--AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAE----EKKKADEAKKKAEEDKKKADELKKAAA 1415

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  953 EKEGTDQelAKLRGQEAAQRTELKelQQTLEQLKIQLVKKEKEHpagGASGEDASGPGTQSETAGKTDAPGPELQALRAE 1032
Cdd:PTZ00121  1416 AKKKADE--AKKKAEEKKKADEAK--KKAEEAKKADEAKKKAEE---AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA 1488

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1033 ISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARElghnQAASASAQRELQALRaKAQDHSKAEEE 1112
Cdd:PTZ00121  1489 KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAD----EAKKAEEKKKADELK-KAEELKKAEEK 1563

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1113 WKAQVARgqQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQklEERLRLLQVETASNSARAAERSS 1192
Cdd:PTZ00121  1564 KKAEEAK--KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE--EAKIKAEELKKAEEEKKKVEQLK 1639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1193 ALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQAL----VSELLPAK 1268
Cdd:PTZ00121  1640 KKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELkkkeAEEKKKAE 1719

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176327 1269 HLCQQLQAEQAAAEKRFREELEQSKQAAgglqaelmRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQ 1340
Cdd:PTZ00121  1720 ELKKAEEENKIKAEEAKKEAEEDKKKAE--------EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 427-1223 2.02e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 89.36  E-value: 2.02e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  427 KEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQ 506
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  507 QLETVEKEKDAK---LESLQQQLQAANdARDNAQTSVTQA--QQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQ 581
Cdd:TIGR02169  252 ELEKLTEEISELekrLEEIEQLLEELN-KKIKDLGEEEQLrvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  582 LKAEQQKTTEREKVVQE----KAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEA----------ESRS 647
Cdd:TIGR02169  331 IDKLLAEIEELEREIEEerkrRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKlkreinelkrELDR 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  648 LMEQREREQKELEQEKAGRKGLEARIQQLE---EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQ 724
Cdd:TIGR02169  411 LQEELQRLSEELADLNAAIAGIEAKINELEeekEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  725 EEARYGAmfqeQLMALKGEKTGQEVQEEAVEIHSEGQPGqQQSQLAQLHASLAKAIQQVQEKevRAQKLVDDLSALQEKM 804
Cdd:TIGR02169  491 ELAEAEA----QARASEERVRGGRAVEEVLKASIQGVHG-TVAQLGSVGERYATAIEVAAGN--RLNNVVVEDDAVAKEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  805 AATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLG-EQQGRP-----FSSThAAVKAMEREAEQMGG-ELE 877
Cdd:TIGR02169  564 IELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEfDPKYEPafkyvFGDT-LVVEDIEAARRLMGKyRMV 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  878 RLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEmRLQNTLNEQRVEFAALQEALAHALTEKEGT 957
Cdd:TIGR02169  643 TLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELS-SLQSELRRIENRLDELSQELSDASRKIGEI 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  958 DQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpaggasgedasgpgtQSETAGKTDAPGPELQALRAEISKLE 1037
Cdd:TIGR02169  722 EKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE----------------LKELEARIEELEEDLHKLEEALNDLE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1038 qqCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQV 1117
Cdd:TIGR02169  786 --ARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1118 ARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREE 1197
Cdd:TIGR02169  864 EELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGED 943

                          810       820
                   ....*....|....*....|....*.
gi 1907176327 1198 VQSLREEVEKQRVVSENSRQELASQA 1223
Cdd:TIGR02169  944 EEIPEEELSLEDVQAELQRVEEEIRA 969
PTZ00121 PTZ00121
MAEBL; Provisional
 470-1232 2.43e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 89.43  E-value: 2.43e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  470 EEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARqqLETVEKEKDAKleSLQQQLQAANDARDNAQTSVTQAQQ---- 545
Cdd:PTZ00121  1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARK--AEEARKAEDAR--KAEEARKAEDAKRVEIARKAEDARKaeea 1169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  546 EKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKR 625
Cdd:PTZ00121  1170 RKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEER 1249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  626 RAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEAR----IQQLEEAHQAETEALRHELAEATASQhrA 701
Cdd:PTZ00121  1250 NNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKkaeeKKKADEAKKKAEEAKKADEAKKKAEE--A 1327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  702 ESECERLIREVESRQKRFEA-RQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAI 780
Cdd:PTZ00121  1328 KKKADAAKKKAEEAKKAAEAaKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKA 1407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  781 QQVQEKEVRAQKlvddlsalQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSTHA 860
Cdd:PTZ00121  1408 DELKKAAAAKKK--------ADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKA 1479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  861 AVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEF 940
Cdd:PTZ00121  1480 EEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKK 1559

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  941 AALQEALAHALTEKEGTDQELAK---LRGQEAAQRTELKELQQTLEQLKIQLVKKEkehpaggasgEDASGPGTQSETAG 1017
Cdd:PTZ00121  1560 AEEKKKAEEAKKAEEDKNMALRKaeeAKKAEEARIEEVMKLYEEEKKMKAEEAKKA----------EEAKIKAEELKKAE 1629

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1018 KTDAPGPELQALRAEisklEQQCQQQQQQVEGLTHSLKSERACRAEQDKaletlqgqleEKARELghnQAASASAQRELQ 1097
Cdd:PTZ00121  1630 EEKKKVEQLKKKEAE----EKKKAEELKKAEEENKIKAAEEAKKAEEDK----------KKAEEA---KKAEEDEKKAAE 1692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1098 ALRAKAQDHSKAEeewkaQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEErlrLLQ 1177
Cdd:PTZ00121  1693 ALKKEAEEAKKAE-----ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAH---LKK 1764

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327 1178 VETASNSARAAERSSALREEVqslREEVEKQRVVSENSRQELASQAERAEELGQE 1232
Cdd:PTZ00121  1765 EEEKKAEEIRKEKEAVIEEEL---DEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 119-752 2.15e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.15e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  119 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPS--------ELEELRGK 190
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELEsrleeleeQLETLRSK 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  191 NESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANH------------LQQLQGAFNDLIEEHSKAS 258
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelqaeleeleeeLEELQEELERLEEALEELR 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  259 QEWAEKQARL---ENELSTALQDKKCLEEKNEILQG----------KLSQLEDQATRLQESPAPEKG------EVLGDAL 319
Cdd:TIGR02168  468 EELEEAEQALdaaERELAQLQARLDSLERLQENLEGfsegvkallkNQSGLSGILGVLSELISVDEGyeaaieAALGGRL 547

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  320 Q-------------LDTLKQEAAKLATD---NTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSN 383
Cdd:TIGR02168  548 QavvvenlnaakkaIAFLKQNELGRVTFlplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  384 LSQAKEELEQASQAQGAQLTAQLT--------SMTG----LNATLQQRDQELASLKEQakkeQAQMLQTMQEQEQAAQGL 451
Cdd:TIGR02168  628 VDDLDNALELAKKLRPGYRIVTLDgdlvrpggVITGgsakTNSSILERRREIEELEEK----IEELEEKIAELEKALAEL 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  452 RQQVEQLSSSLKLKEQQLEEAAKEQEATRQDhAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND 531
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  532 ARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQ-----------QKTTEREKVVQEKA 600
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATErrledleeqieELSEDIESLAAEIE 862

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  601 QLQEQLRALE---ESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE 677
Cdd:TIGR02168  863 ELEELIEELEselEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  678 EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRF--------EARQQEEARYGAMFQEQLMALKGEKTGQEV 749
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022


                   ...
gi 1907176327  750 QEE 752
Cdd:TIGR02168 1023 IEE 1025
PTZ00121 PTZ00121
MAEBL; Provisional
 251-980 9.44e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.04  E-value: 9.44e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  251 IEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLedqATRLQESPAPEKGEVLGDALQLDTLKQEAAK 330
Cdd:PTZ00121  1111 AEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEI---ARKAEDARKAEEARKAEDAKKAEAARKAEEV 1187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  331 LATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQlasliadlqSSVSNLSQAKEELEQASQAQGAQLTAQLTSMT 410
Cdd:PTZ00121  1188 RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKA---------EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFE 1258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  411 GLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGL-RQQVEQLSSslKLKEQQLEEAAKEQEATRQDHAQQLAI 489
Cdd:PTZ00121  1259 EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEeKKKADEAKK--KAEEAKKADEAKKKAEEAKKKADAAKK 1336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  490 VAE----AREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQtsvtqaQQEKAELSQKIGELHAciEASH 565
Cdd:PTZ00121  1337 KAEeakkAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAE------EKKKADEAKKKAEEDK--KKAD 1408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  566 QEQRQVQARVTELEAQLKAEQ-QKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAE 644
Cdd:PTZ00121  1409 ELKKAAAAKKKADEAKKKAEEkKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA 1488

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  645 SRSLMEQREREQKELEQEKAGRKGLEAR----IQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFE 720
Cdd:PTZ00121  1489 KKKAEEAKKKADEAKKAAEAKKKADEAKkaeeAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEE 1568

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  721 ARQQEEARYGAMFQEQLMalkgeKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSAL 800
Cdd:PTZ00121  1569 AKKAEEDKNMALRKAEEA-----KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA 1643

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  801 QEKMAATN----KEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLG--EQQGRPFSSTHAAVKAMEREAEQMGG 874
Cdd:PTZ00121  1644 EEKKKAEElkkaEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKkeAEEAKKAEELKKKEAEEKKKAEELKK 1723

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  875 ELE---------RLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVE------ 939
Cdd:PTZ00121  1724 AEEenkikaeeaKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDkkikdi 1803

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907176327  940 ---FAALQEA----LAHALTEKEGTDQELAKLRGQEAAQRTELKELQQ 980
Cdd:PTZ00121  1804 fdnFANIIEGgkegNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEK 1851
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 868-1587 2.17e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 2.17e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  868 EAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEmRLQNTLNEQRVEFAALQEAL 947
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELY-ALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  948 AHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETagktdapgpELQ 1027
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE---------QLE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1028 ALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELghNQAASASAQRELQALRAKAQDHS 1107
Cdd:TIGR02168  383 TLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLE 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1108 KAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARA 1187
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1188 AerssALREEVQSLreevekqrVVSENSRQELASQAERAEELGQ----ELKAWQEKFFQKEQALSALQLEHTSTQALVSE 1263
Cdd:TIGR02168  541 A----ALGGRLQAV--------VVENLNAAKKAIAFLKQNELGRvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1264 LLPAK-HLCQQLQAEQAAAEKRFREELEQSKQAAGG-----LQAELMRAQ-RELGELGSLRQKIVEQERAAQQLRAEKAS 1336
Cdd:TIGR02168  609 KFDPKlRKALSYLLGGVLVVDDLDNALELAKKLRPGyrivtLDGDLVRPGgVITGGSAKTNSSILERRREIEELEEKIEE 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1337 YAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDAEThLAEMRQEAQSTSRELEVMTAKY 1416
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELE-ELSRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELEAEIEEL 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1417 EGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQ 1496
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1497 LNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQ-----------DLEELQKENKELRSEAERLGRELQQ 1565
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAllrseleelseELRELESKRSELRRELEELREKLAQ 926

                          730       740
                   ....*....|....*....|..
gi 1907176327 1566 AGLKTKEAEQTCRHLTAQVRSL 1587
Cdd:TIGR02168  927 LELRLEGLEVRIDNLQERLSEE 948
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 1-59 6.12e-14

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 71.06  E-value: 6.12e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327    1 MELAKMIMLFLYQSTMSSRNlrDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFL 59
Cdd:cd22224     91 LELAKVLLLLLYHSMMNNNL--TLEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 160-793 1.54e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.65  E-value: 1.54e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  160 MQQRIDHLALLNEKQAASSQEpsELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANH 239
Cdd:TIGR02169  267 LEEIEQLLEELNKKIKDLGEE--EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELERE 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  240 LQQLQGAFNDLIEEHSKASQEWAEKQARLEN---ELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLg 316
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELEDLRAELEEvdkEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA- 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  317 dalqldTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQ 396
Cdd:TIGR02169  424 ------DLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEA 497

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  397 AQGAQLTAQLTS-------------MTGLNATLQQRDQELASLKEQA--KKEQAQMLQTMQEQEQAAQGLR--------- 452
Cdd:TIGR02169  498 QARASEERVRGGraveevlkasiqgVHGTVAQLGSVGERYATAIEVAagNRLNNVVVEDDAVAKEAIELLKrrkagratf 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  453 ------QQVEQLSSSLKLK------------EQQLEEAAK---------EQEATRQDHAQQL--------------AIVA 491
Cdd:TIGR02169  578 lplnkmRDERRDLSILSEDgvigfavdlvefDPKYEPAFKyvfgdtlvvEDIEAARRLMGKYrmvtlegelfeksgAMTG 657

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  492 EAREASLRERDTARQQLEtvEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQV 571
Cdd:TIGR02169  658 GSRAPRGGILFSRSEPAE--LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL 735

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  572 QARVTELEAQLKAEQQKTT----EREKVVQEKAQLQEQLRALEESLKITKGSL--------EEEKRRAADALKEQQCRAT 639
Cdd:TIGR02169  736 KERLEELEEDLSSLEQEIEnvksELKELEARIEELEEDLHKLEEALNDLEARLshsripeiQAELSKLEEEVSRIEARLR 815

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  640 EMEAESRSLMEQREREQKELEQEKAGRKGLEARI---QQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQ 716
Cdd:TIGR02169  816 EIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIksiEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELE 895

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176327  717 KRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEavEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKL 793
Cdd:TIGR02169  896 AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE--ELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 554-1461 9.25e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.95  E-value: 9.25e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  554 IGELHACIEASHQEQRQVQARVTELEAQLKaeqQKTTEREKVVQEKAQLqEQLRALEESLKITKGSLEEEKRRAADALKE 633
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIID---EKRQQLERLRREREKA-ERYQALLKEKREYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  634 Q-QCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREV 712
Cdd:TIGR02169  241 AiERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  713 ESRQKRFEARQQEearygamFQEQLMALKGEKTGQEVQEEAVeihsegqpgqqQSQLAQLHASLAKAIQQVQEKEVRAQK 792
Cdd:TIGR02169  321 EERLAKLEAEIDK-------LLAEIEELEREIEEERKRRDKL-----------TEEYAELKEELEDLRAELEEVDKEFAE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  793 LVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLkEPPRAANRASDQLGEQQgrpfssthAAVKAMEREAEQM 872
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA-DLNAAIAGIEAKINELE--------EEKEDKALEIKKQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  873 GGELERLRAALIKsqgqqqeergqQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRvEFAALQEALAHALT 952
Cdd:TIGR02169  454 EWKLEQLAADLSK-----------YEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVR-GGRAVEEVLKASIQ 521

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  953 EKEGTDQELAKLRGQ-----EAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGAS------GEDASGPGTQSETAGKTDa 1021
Cdd:TIGR02169  522 GVHGTVAQLGSVGERyataiEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATflplnkMRDERRDLSILSEDGVIG- 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1022 pgpelqaLRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKA-LETLQGQLEEKARELGHNQAASASAQRELQALR 1100
Cdd:TIGR02169  601 -------FAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEP 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1101 AKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVET 1180
Cdd:TIGR02169  674 AELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEI 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1181 ASNSA---RAAERSSALREEVQSLREEVEKqrVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTST 1257
Cdd:TIGR02169  754 ENVKSelkELEARIEELEEDLHKLEEALND--LEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1258 QALVSELLpakhlcqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGS-----------LRQKIVEQERA 1326
Cdd:TIGR02169  832 EKEIQELQ-------EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESrlgdlkkerdeLEAQLRELERK 904

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1327 AQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqarekyvqelaavrtdaETHLAEMRQEAQSTS 1406
Cdd:TIGR02169  905 IEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS-----------------LEDVQAELQRVEEEI 967

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327 1407 RELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLevfqREQTKQVEELSKK 1461
Cdd:TIGR02169  968 RALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI----LERIEEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 951-1601 9.41e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.95  E-value: 9.41e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  951 LTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDasgpgtqsETAGKTDAPGPELQALR 1030
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKD--------LGEEEQLRVKEKIGELE 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1031 AEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAE 1110
Cdd:TIGR02169  301 AEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1111 EEWKAQVargqqeaerkssliSSLEEEVSILNRqvlekegESKELKRLVVAESEKSQKLEERLRLLQVETasnsARAAER 1190
Cdd:TIGR02169  381 AETRDEL--------------KDYREKLEKLKR-------EINELKRELDRLQEELQRLSEELADLNAAI----AGIEAK 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1191 SSALREEVQSLREEVEKQRvvsensrqelasqaERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKhl 1270
Cdd:TIGR02169  436 INELEEEKEDKALEIKKQE--------------WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA-- 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1271 cqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQR------ELGELGSLRQKIVEQERAAQQ----LRAEKASYAEQ 1340
Cdd:TIGR02169  500 --RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGEryataiEVAAGNRLNNVVVEDDAVAKEaielLKRRKAGRATF 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1341 LSMLKKAHGLLaeENRGLGERANLGRQFLEVELDQARE---KYVQELAAVRTDAETHLAEMRQEAQSTsreLE------- 1410
Cdd:TIGR02169  578 LPLNKMRDERR--DLSILSEDGVIGFAVDLVEFDPKYEpafKYVFGDTLVVEDIEAARRLMGKYRMVT---LEgelfeks 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1411 -VMTAKY------EGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLtehdqasKVQQQKLKAFQAQR 1483
Cdd:TIGR02169  653 gAMTGGSraprggILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL-------SDASRKIGEIEKEI 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1484 GESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLE--ELQKENKELRSEAERLGR 1561
Cdd:TIGR02169  726 EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEE 805

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|
gi 1907176327 1562 ELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1601
Cdd:TIGR02169  806 EVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1143-1611 1.11e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 73.80  E-value: 1.11e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1143 RQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQ-VETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELAS 1221
Cdd:COG4913    241 HEALEDAREQIELLEPIRELAERYAAARERLAELEyLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDA 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1222 QAERAEEL--------GQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqqlQAEQAAAEKRFREELEQSK 1293
Cdd:COG4913    321 LREELDELeaqirgngGDRLEQLEREIERLERELEERERRRARLEALLAAL----------GLPLPASAEEFAALRAEAA 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1294 QAAGGLQAELMRAQRELGELgslRQKIVEQERAAQQLRAEKAS-----------YAEQLSMLKKAHGLLAEENRGLGEra 1362
Cdd:COG4913    391 ALLEALEEELEALEEALAEA---EAALRDLRRELRELEAEIASlerrksniparLLALRDALAEALGLDEAELPFVGE-- 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1363 nlgrqFLEVELDQAR--------------------EKYVQELAAV-RTDAETHL------------AEMRQEAQSTSREL 1409
Cdd:COG4913    466 -----LIEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVnRLHLRGRLvyervrtglpdpERPRLDPDSLAGKL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1410 EVMTAKYEGAKVKVLEERQRFqeerqkltAQVEQLEVFQRE--------QTKQveelSKKLTEHDQASKVQQQ------- 1474
Cdd:COG4913    541 DFKPHPFRAWLEAELGRRFDY--------VCVDSPEELRRHpraitragQVKG----NGTRHEKDDRRRIRSRyvlgfdn 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1475 --KLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQ--KLQEQLQDLEELQKENK 1550
Cdd:COG4913    609 raKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREiaELEAELERLDASSDDLA 688

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176327 1551 ELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDAL 1611
Cdd:COG4913    689 ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 682-1562 1.54e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 1.54e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  682 AETEALRHELAEATASQHRAESecerLIREVESRQKRFEARQQEEARYgamfqeqlMALKGEKTGQEVQEEAVEIHS-EG 760
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDL----IIDEKRQQLERLRREREKAERY--------QALLKEKREYEGYELLKEKEAlER 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  761 QPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEK-MAATNKEVACLKTLVLKAgeqqeTASLELLKEPPRA 839
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVKEKIGEL-----EAEIASLERSIAE 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  840 ANRASDQLGEQQGRPFSSTHAavkaMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEK 919
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDK----LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  920 AAKAELEMrLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQ-------QTLEQLKIQLVKK 992
Cdd:TIGR02169  389 DYREKLEK-LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAleikkqeWKLEQLAADLSKY 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  993 EKEHpaggasgedasgpgtqSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGlthslksERACRAEQDKALETLQ 1072
Cdd:TIGR02169  468 EQEL----------------YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRG-------GRAVEEVLKASIQGVH 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1073 GQLEEKAR-ELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQ------QEAERKSSLISSLEEEVSI---LN 1142
Cdd:TIGR02169  525 GTVAQLGSvGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRatflplNKMRDERRDLSILSEDGVIgfaVD 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1143 RQVLEKEGESKEL----KRLVVAESEKSQKLEERLRLLQVET-----------ASNSARAAE-RSSALREEVQSLREEVE 1206
Cdd:TIGR02169  605 LVEFDPKYEPAFKyvfgDTLVVEDIEAARRLMGKYRMVTLEGelfeksgamtgGSRAPRGGIlFSRSEPAELQRLRERLE 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1207 KQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFR 1286
Cdd:TIGR02169  685 GLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELE 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1287 EELEQSKQAAGGLQAELMRAQRELGelgslRQKIVEQERAAQQLRAEKASYAEQLSMLKkahgllAEENRGLGERANLgr 1366
Cdd:TIGR02169  765 ARIEELEEDLHKLEEALNDLEARLS-----HSRIPEIQAELSKLEEEVSRIEARLREIE------QKLNRLTLEKEYL-- 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1367 qfleveldqarEKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLE---ERQRFQEERQKLTAQVEQ 1443
Cdd:TIGR02169  832 -----------EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDlesRLGDLKKERDELEAQLRE 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1444 LEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTqLNELQAQLSQKEQAAEHYKLQMEKAKT 1523
Cdd:TIGR02169  901 LERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS-LEDVQAELQRVEEEIRALEPVNMLAIQ 979

                          890       900       910
                   ....*....|....*....|....*....|....*....
gi 1907176327 1524 HYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRE 1562
Cdd:TIGR02169  980 EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
151-658 2.24e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 72.38  E-value: 2.24e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  151 TEKDAQIAMMQQRIDHlALLNEKQAASSQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS 220
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  221 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQ 290
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  291 GKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQL 370
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  371 ASLIADLQSSVSNLSQAKEELEQA--------------------SQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQA 430
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAGkcpecgqpvegsphvetieeDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  431 K-----KEQAQMLQ--------TMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaiVAEAREAS 497
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEARE--------EVAELNSK 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  498 LRERDTARQQLETVEkEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACI-EASHQEQRQVQARVT 576
Cdd:PRK02224   581 LAELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFdEARIEEAREDKERAE 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  577 ELEAQLKAE-QQKTTEREKVVQEKAQLQEQLRALEEsLKITKGSLeEEKRRAADALKEQQCRATEMEAESRSLMEQRERE 655
Cdd:PRK02224   660 EYLEQVEEKlDELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLRAELRQRNVE 737


                   ...
gi 1907176327  656 QKE 658
Cdd:PRK02224   738 TLE 740
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
445-1057 2.28e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 72.64  E-value: 2.28e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  445 EQAAQGLRQQVEQLSSSlklkEQQLEEAAKeqeatRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDA-KLESLQ 523
Cdd:COG4913    224 FEAADALVEHFDDLERA----HEALEDARE-----QIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQrRLELLE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  524 QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHAcieashQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQ 603
Cdd:COG4913    295 AELEELRAELARLEAELERLEARLDALREELDELEA------QIRGNGGDRLEQLEREIERLER---ELEERERRRARLE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  604 EQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEeahqAE 683
Cdd:COG4913    366 ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIP----AR 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  684 TEALRHELAEATASqhrAESE----CErLIrEVESRQKRFEA------RQQE-----EARYGAMFQEqlmALKGEKTGQE 748
Cdd:COG4913    442 LLALRDALAEALGL---DEAElpfvGE-LI-EVRPEEERWRGaiervlGGFAltllvPPEHYAAALR---WVNRLHLRGR 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  749 VQEEAVEIHSEGQPGQQ---QSQLAQLHASLAKAIQQVQEKEVRAQKL--VDDLSAL-QEKMAATnkeVACLKTLVLKAG 822
Cdd:COG4913    514 LVYERVRTGLPDPERPRldpDSLAGKLDFKPHPFRAWLEAELGRRFDYvcVDSPEELrRHPRAIT---RAGQVKGNGTRH 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  823 EQQetaslellkepPRAANRASDQLGeqqgrpfSSTHAAVKAMEREAEQMGGELERLRAALikSQGQQQEERGQQEREVA 902
Cdd:COG4913    591 EKD-----------DRRRIRSRYVLG-------FDNRAKLAALEAELAELEEELAEAEERL--EALEAELDALQERREAL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  903 RLTQERGQAQADLAQEKAAKAELEMRLQNtLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTL 982
Cdd:COG4913    651 QRLAEYSWDEIDVASAEREIAELEAELER-LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEEL 729

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327  983 EQLKIQLVKKEKEHPAGGASGEDAsgpgtQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSE 1057
Cdd:COG4913    730 DELQDRLEAAEDLARLELRALLEE-----RFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNRE 799
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 243-1232 2.64e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 2.64e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  243 LQGAFNDLIEEHSKASQEWAEKQA---RLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPApekgevlgDAL 319
Cdd:TIGR02169  140 LQGDVTDFISMSPVERRKIIDEIAgvaEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERE--------KAE 211

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  320 QLDTLKQEaaKLATDNTQLQTRVETLEcergKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 399
Cdd:TIGR02169  212 RYQALLKE--KREYEGYELLKEKEALE----RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG 285

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  400 AQLTAQLTSmtglnatlqqrdqELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSslklKEQQLEEAAKEQEAT 479
Cdd:TIGR02169  286 EEEQLRVKE-------------KIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK----LLAEIEELEREIEEE 348

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  480 RQDHAQQLAIVAEAREaslrERDTARQQLETVEKEKDA---KLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGE 556
Cdd:TIGR02169  349 RKRRDKLTEEYAELKE----ELEDLRAELEEVDKEFAEtrdELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD 424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  557 LHACIEASHQEQRQVQARVTELEAQLKaeqQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQc 636
Cdd:TIGR02169  425 LNAAIAGIEAKINELEEEKEDKALEIK---KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR- 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  637 ratemeaESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETE-ALRHELAEATASQHRAESECERLIREVESR 715
Cdd:TIGR02169  501 -------ASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRRKAG 573

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  716 QKRFEARQQeearygaMFQEQLMALKGEKTGqeVQEEAVEihsegqpgqqqsqLAQLHASLAKAIQQVqekeVRAQKLVD 795
Cdd:TIGR02169  574 RATFLPLNK-------MRDERRDLSILSEDG--VIGFAVD-------------LVEFDPKYEPAFKYV----FGDTLVVE 627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  796 DLSALQEKM-----------------AATNKEVACLKTLVLKAGEQQETASL-ELLKEPPRAANRASDQLGEQQGRPFSS 857
Cdd:TIGR02169  628 DIEAARRLMgkyrmvtlegelfeksgAMTGGSRAPRGGILFSRSEPAELQRLrERLEGLKRELSSLQSELRRIENRLDEL 707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  858 THAAvkameREAEQMGGELERlraaliksqgqqqeergqqerevarltqERGQAQADLAQEKAAKAELEMRLQntlneqr 937
Cdd:TIGR02169  708 SQEL-----SDASRKIGEIEK----------------------------EIEQLEQEEEKLKERLEELEEDLS------- 747

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  938 vefaALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpaggasgedasgpgTQSETAG 1017
Cdd:TIGR02169  748 ----SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS---------------KLEEEVS 808

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1018 KTDApgpELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQ 1097
Cdd:TIGR02169  809 RIEA---RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG 885

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1098 ALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAE------SEKSQKLEE 1171
Cdd:TIGR02169  886 DLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsledvQAELQRVEE 965

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176327 1172 RLRLLQvetaSNSARAAERSsalrEEVQSLREEVEKQRVVSENSRQELASQAERAEELGQE 1232
Cdd:TIGR02169  966 EIRALE----PVNMLAIQEY----EEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 358-556 8.60e-12

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 71.02  E-value: 8.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  358 AERSRFEDEKQQLASLIADLQSSVSNLSQAKeeLEQASQAQGAQL-------TAQLTSMT-GLNAtLQQRDQELASLKEQ 429
Cdd:NF012221  1569 ADRQRLEQEKQQQLAAISGSQSQLESTDQNA--LETNGQAQRDAIleesravTKELTTLAqGLDA-LDSQATYAGESGDQ 1645

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  430 AKKEQAQ-MLQTMQEQ-EQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQ-----QLAIVAEAREASLRERD 502
Cdd:NF012221  1646 WRNPFAGgLLDRVQEQlDDAKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQnqanaEQDIDDAKADAEKRKDD 1725

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907176327  503 TARQQLETVEKEKDAKLESLQQQLQAANDARdNAQTSVTQAQQEKAELSQKIGE 556
Cdd:NF012221  1726 ALAKQNEAQQAESDANAAANDAQSRGEQDAS-AAENKANQAQADAKGAKQDESD 1778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1374-1615 2.74e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.20  E-value: 2.74e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1374 DQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLevfqREQTK 1453
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1454 QVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKthyDAKKQQNQ 1533
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE---EALLEAEA 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1534 KLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKS 1613
Cdd:COG1196    373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452


                   ..
gi 1907176327 1614 RE 1615
Cdd:COG1196    453 EL 454
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1084-1630 3.10e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 68.79  E-value: 3.10e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1084 HNQAASASAQRE-LQALRAKAQDHSKAEEEwkaqvaRGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAE 1162
Cdd:COG4913    241 HEALEDAREQIElLEPIRELAERYAAARER------LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1163 SEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQR-----------VVSENSRQELASQ----AERAE 1227
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRarleallaalgLPLPASAEEFAALraeaAALLE 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1228 ELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL------LPAKHLcqqlqaeqaaaekRFREELEqskQAAGGLQA 1301
Cdd:COG4913    395 ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLerrksnIPARLL-------------ALRDALA---EALGLDEA 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1302 EL--------MRAQREL------GELGSLRQKI-VEQERAAQQLRaekasYAEQLSMLKKAHGLLAEENRGLGERANLGR 1366
Cdd:COG4913    459 ELpfvgelieVRPEEERwrgaieRVLGGFALTLlVPPEHYAAALR-----WVNRLHLRGRLVYERVRTGLPDPERPRLDP 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1367 QFL----EVELDQAREkYVQELAAVRTDAE--THLAEMRQEAQ--------STSRELEVMTAKYEGAKVKVL-----EER 1427
Cdd:COG4913    534 DSLagklDFKPHPFRA-WLEAELGRRFDYVcvDSPEELRRHPRaitragqvKGNGTRHEKDDRRRIRSRYVLgfdnrAKL 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1428 QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRgesqqEVQRLQTQLNELQA---QL 1504
Cdd:COG4913    613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAER-----EIAELEAELERLDAssdDL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1505 SQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQV 1584
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVEREL 767

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1907176327 1585 R-SLEAQVAHADQQLRDL-GKFQVATDALKSREPQVKPQLDLSIDSLD 1630
Cdd:COG4913    768 ReNLEERIDALRARLNRAeEELERAMRAFNREWPAETADLDADLESLP 815
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 289-868 3.47e-11

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 68.71  E-value: 3.47e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  289 LQGKLSQLEDQATRLQESpapeKGEVLGDALQLDTLKQEAA--------KLATDNTQLQTRVETLECERGKQEAQLLAER 360
Cdd:pfam12128  246 LQQEFNTLESAELRLSHL----HFGYKSDETLIASRQEERQetsaelnqLLRTLDDQWKEKRDELNGELSAADAAVAKDR 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  361 SRFED-EKQQLASLIADLQSSVSNLSQA---KEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQ 436
Cdd:pfam12128  322 SELEAlEDQHGAFLDADIETAAADQEQLpswQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAK 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  437 MLQTMQEQEQAAQG--------LRQQVEQLSSSLKLKEQQLEEAAKEqEATRQDHAQQLAIVAEAREASLRERDTARQQL 508
Cdd:pfam12128  402 IREARDRQLAVAEDdlqaleseLREQLEAGKLEFNEEEYRLKSRLGE-LKLRLNQATATPELLLQLENFDERIERAREEQ 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  509 EtvekEKDAKLESLQQQLQAANDARDNA-------QTSVTQAQQEKAELSQ----KIGELHACIEASHQEQRQVQARVTE 577
Cdd:pfam12128  481 E----AANAEVERLQSELRQARKRRDQAsealrqaSRRLEERQSALDELELqlfpQAGTLLHFLRKEAPDWEQSIGKVIS 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  578 LEAQLKAEQQKTTEREKVVQEKAQLQEQLRaLEESLKITKGSLEEEKRRAADALKE----QQCRATEMEAESRSLMEQRE 653
Cdd:pfam12128  557 PELLHRTDLDPEVWDGSVGGELNLYGVKLD-LKRIDVPEWAASEEELRERLDKAEEalqsAREKQAAAEEQLVQANGELE 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  654 REQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAM- 732
Cdd:pfam12128  636 KASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTe 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  733 FQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVA 812
Cdd:pfam12128  716 KQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVL 795

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327  813 CLKTLvlkageQQETASLE--LLKEPPRAANRASDQLGEQQGRPFSSTHAAVKAMERE 868
Cdd:pfam12128  796 RYFDW------YQETWLQRrpRLATQLSNIERAISELQQQLARLIADTKLRRAKLEME 847
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 420-1247 3.98e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.46  E-value: 3.98e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  420 DQELASLKEQAKKEQAQmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQlAIVAEAREASLR 499
Cdd:pfam02463  159 EEEAAGSRLKRKKKEAL-KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE-YLLYLDYLKLNE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  500 ERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhacIEASHQEQRQVQARVTELE 579
Cdd:pfam02463  237 ERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKE---EEELKSELLKLERRKVDDE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  580 AQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKEL 659
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  660 EQEKAGRKGLEARIQqlEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMA 739
Cdd:pfam02463  394 EEELELKSEEEKEAQ--LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  740 LKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEK-----------------EVRAQKLVDDLSALQE 802
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDgvggriisahgrlgdlgVAVENYKVAISTAVIV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  803 KMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPF--SSTHAAVKAMEREAEQMGGELERLR 880
Cdd:pfam02463  552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNlaQLDKATLEADEDDKRAKVVEGILKD 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  881 AALIKSQGQQQEERGQQEREVARL-----TQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKE 955
Cdd:pfam02463  632 TELTKLKESAKAKESGLRKGVSLEeglaeKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  956 GTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpagGASGEDASGPGTQSETAGKTDAPGPELQALRAEISK 1035
Cdd:pfam02463  712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEE----EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1036 LEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKA 1115
Cdd:pfam02463  788 VEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEE 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1116 QVARG------QQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAE 1189
Cdd:pfam02463  868 LLQELllkeeeLEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADE 947

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176327 1190 RSSA------LREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQAL 1247
Cdd:pfam02463  948 KEKEennkeeEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAI 1011
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
232-711 9.46e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 67.25  E-value: 9.46e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  232 KVREFANHLQQLQGAFNDLIEEHSKASQ-----------EWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQA 300
Cdd:COG4913    246 DAREQIELLEPIRELAERYAAARERLAEleylraalrlwFAQRRLELLEAELEELRAELARLEAELERLEARLDALREEL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  301 TRLQESPAPEKGEVLGD-ALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQS 379
Cdd:COG4913    326 DELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEE 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  380 SVSNLSQAKEELEQASQaqgaQLTAQLTSMTGLNATLQQRDQEL-ASLKEQAKKEQAQM-----LQTMQEQEQAAQG--- 450
Cdd:COG4913    406 ALAEAEAALRDLRRELR----ELEAEIASLERRKSNIPARLLALrDALAEALGLDEAELpfvgeLIEVRPEEERWRGaie 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  451 --LRQQ-----------------VEQLSSSLKLKEQQLEEAAKEQEATRQDH---AQQLAI----VAEAREASLRER--- 501
Cdd:COG4913    482 rvLGGFaltllvppehyaaalrwVNRLHLRGRLVYERVRTGLPDPERPRLDPdslAGKLDFkphpFRAWLEAELGRRfdy 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  502 ---DTArQQLETVEK---------------EKD----------------AKLESLQQQLQAANDARDNAQTSVTQAQQEK 547
Cdd:COG4913    562 vcvDSP-EELRRHPRaitragqvkgngtrhEKDdrrrirsryvlgfdnrAKLAALEAELAELEEELAEAEERLEALEAEL 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  548 AELSQKIGELHACIEASHQEQ--RQVQARVTELEAQLKAE-------QQKTTEREKVVQEKAQLQEQLRALEEslkiTKG 618
Cdd:COG4913    641 DALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLdassddlAALEEQLEELEAELEELEEELDELKG----EIG 716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  619 SLEEEKRRAADALKEQQCRATEMEAESRSLMEQRereqkeleqekagrkgLEARIQQL--EEAHQAETEALRHELAEATA 696
Cdd:COG4913    717 RLEKELEQAEEELDELQDRLEAAEDLARLELRAL----------------LEERFAAAlgDAVERELRENLEERIDALRA 780

                          570
                   ....*....|....*
gi 1907176327  697 SQHRAESECERLIRE 711
Cdd:COG4913    781 RLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1286-1591 1.34e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 1.34e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1286 REELEQSKQAAGGLQAELMRAQRE--LGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhgllaEENRGLGERAN 1363
Cdd:TIGR02169  217 LKEKREYEGYELLKEKEALERQKEaiERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKK-----IKDLGEEEQLR 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1364 LGRQFLEVELDQAREKyvqelaavrtDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQ 1443
Cdd:TIGR02169  292 VKEKIGELEAEIASLE----------RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1444 LEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKT 1523
Cdd:TIGR02169  362 LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE 441

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176327 1524 HYDAK----KQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQV 1591
Cdd:TIGR02169  442 EKEDKaleiKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE 513
PTZ00121 PTZ00121
MAEBL; Provisional
 1052-1575 2.41e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.32  E-value: 2.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1052 HSLKSERACRAEQDKALETLQGQLEEKARElgHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLI 1131
Cdd:PTZ00121  1056 HEGKAEAKAHVGQDEGLKPSYKDFDFDAKE--DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA 1133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1132 SSLEEEVSIlnrqvlEKEGESKELKRLVVA-ESEKSQKLEERLRLLQVETASNSARAAERSSAlrEEVQSLRE--EVEKQ 1208
Cdd:PTZ00121  1134 RKAEDARKA------EEARKAEDAKRVEIArKAEDARKAEEARKAEDAKKAEAARKAEEVRKA--EELRKAEDarKAEAA 1205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1209 RVVSENSRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcQQLQAEQAAAEKRFREE 1288
Cdd:PTZ00121  1206 RKAEEERKAEEARKAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF--ARRQAAIKAEEARKADE 1282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1289 LEQSKQAAgglQAELMRAQRELGELGSLRQKiVEQERAAQQLRAEKASYAEQLSMLKKAhgllAEENRGLGERAnlgrqf 1368
Cdd:PTZ00121  1283 LKKAEEKK---KADEAKKAEEKKKADEAKKK-AEEAKKADEAKKKAEEAKKKADAAKKK----AEEAKKAAEAA------ 1348

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1369 leveldqarekyvqelaavrtdaethlaemRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKltaqveqlevfq 1448
Cdd:PTZ00121  1349 ------------------------------KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK------------ 1386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1449 REQTKQVEELSKKLTEHDQasKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAK 1528
Cdd:PTZ00121  1387 AEEKKKADEAKKKAEEDKK--KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1529 KQQNQKLQEQLQDLEELQKENKELRSEAERLGR---ELQQAGLKTKEAEQ 1575
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKkadEAKKAAEAKKKADE 1514
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 200-679 2.51e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 65.81  E-value: 2.51e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  200 ETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENeLSTALQDK 279
Cdd:TIGR04523  135 ENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSN-LKKKIQKN 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  280 KCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLAT---DNTQLQTRVETLECERGKQEAQL 356
Cdd:TIGR04523  214 KSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKqlsEKQKELEQNNKKIKELEKQLNQL 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  357 LAERSRFEDEKQQ--LASLIADLQSSVSNLSQAKEELEQASQA------QGAQLTAQLTSMTGLNATLQQRDQELASLKE 428
Cdd:TIGR04523  294 KSEISDLNNQKEQdwNKELKSELKNQEKKLEEIQNQISQNNKIisqlneQISQLKKELTNSESENSEKQRELEEKQNEIE 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  429 QAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEARE--ASLRERDTArq 506
Cdd:TIGR04523  374 KLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSeiKDLTNQDSV-- 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  507 qLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQE--------------KAELSQKIGELHACIEASHQEQRQVQ 572
Cdd:TIGR04523  452 -KELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKElkskekelkklneeKKELEEKVKDLTKKISSLKEKIEKLE 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  573 ARVTELE---AQLKAEQQKTTEREKVVQEKAQLQEQLRALEEsLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLM 649
Cdd:TIGR04523  531 SEKKEKEskiSDLEDELNKDDFELKKENLEKEIDEKNKEIEE-LKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKE 609

                          490       500       510
                   ....*....|....*....|....*....|
gi 1907176327  650 EQREREQKELEQEKAGRKGLEARIQQLEEA 679
Cdd:TIGR04523  610 KKISSLEKELEKAKKENEKLSSIIKNIKSK 639
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 780-1599 4.79e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 4.79e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  780 IQQVQEKEVRAQKLVDDLSALQEKMAaTNKEVAcLKTLVLKAgEQQETASLELLKEppRAANRASDQLGEQQgrpFSSTH 859
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLR-REREKA-ERYQALLK-EKREYEGYELLKE--KEALERQKEAIERQ---LASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  860 AAVKAMEREAEQMGGELERLRAALiksQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVE 939
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLL---EELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  940 FAALQEALAhaltEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASgedasgpgtQSETAGKT 1019
Cdd:TIGR02169  328 EAEIDKLLA----EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE---------LKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1020 DAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQAL 1099
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDL 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1100 RAKAQDHSKAEEEWKAQVARG---QQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSqkLEERLRLL 1176
Cdd:TIGR02169  475 KEEYDRVEKELSKLQRELAEAeaqARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVA--AGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1177 QVETASNSARAAE---RSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQL- 1252
Cdd:TIGR02169  553 VVEDDAVAKEAIEllkRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAa 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1253 -EHTSTQALVS---ELLPAKHLCQQLQAEQAAAEKRFREELEQSKQaaggLQAELMRAQRELGelgSLRQKIVEQERAAQ 1328
Cdd:TIGR02169  633 rRLMGKYRMVTlegELFEKSGAMTGGSRAPRGGILFSRSEPAELQR----LRERLEGLKRELS---SLQSELRRIENRLD 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1329 QLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDaethLAEMRQEAQSTSRE 1408
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS-SLEQEIENVKSELKELEAR----IEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1409 LEVMTAKYEGAKVKVLEERQRFQEE-RQKLTAQVEQLEvfqreqtkqveelskkltehdqaskvqqQKLKAFQAQRGESQ 1487
Cdd:TIGR02169  781 LNDLEARLSHSRIPEIQAELSKLEEeVSRIEARLREIE----------------------------QKLNRLTLEKEYLE 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1488 QEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKakthydaKKQQNQKLQEQLQDLEE----LQKENKELRSEAERLGREL 1563
Cdd:TIGR02169  833 KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE-------LEEELEELEAALRDLESrlgdLKKERDELEAQLRELERKI 905

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 1907176327 1564 QQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLR 1599
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKG 941
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 513-721 1.11e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 62.47  E-value: 1.11e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  513 KEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTER 592
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  593 ekvvqeKAQLQEQLRALEESLKITK--------------------GSLEEEKRRAADALKEQQCRATEMEAESRSLMEQR 652
Cdd:COG4942    103 ------KEELAELLRALYRLGRQPPlalllspedfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327  653 EREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEA 721
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
124-759 2.17e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.77  E-value: 2.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  124 RLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLAL----LNEKQAASSQEPSELEELRGKNESLTVRLH 199
Cdd:PRK03918   169 EVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSelpeLREELEKLEKEVKELEELKEEIEELEKELE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  200 ETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFaNHLQQLQGAFNDLIEEHSkasqEWAEKQARLENELSTALQDK 279
Cdd:PRK03918   249 SLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYIKLSEFYE----EYLDELREIEKRLSRLEEEI 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  280 KCLEEKNEILQGKLSQLEDQATRLQESpAPEKGEVLGDALQLDTLKQEAAKLatdnTQLQTRVETLECERGKQEAQLLAE 359
Cdd:PRK03918   324 NGIEERIKELEEKEERLEELKKKLKEL-EKRLEELEERHELYEEAKAKKEEL----ERLKKRLTGLTPEKLEKELEELEK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  360 R-SRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQ---AQGAQLTAQ-----LTSMTGLNATLQQRDQELASLKEQA 430
Cdd:PRK03918   399 AkEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGkcpVCGRELTEEhrkelLEEYTAELKRIEKELKEIEEKERKL 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  431 KKEQAQmLQTMQEQEQAAQGLRQQVEQLSS-SLKLKEQQLEEAAKEqeatrqdhaqqlaivAEAREASLRERDTARQQLE 509
Cdd:PRK03918   479 RKELRE-LEKVLKKESELIKLKELAEQLKElEEKLKKYNLEELEKK---------------AEEYEKLKEKLIKLKGEIK 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  510 TVEKEKDaKLESLQQQLQAANDARDNaqtsvtqAQQEKAELSQKIGELhacieaSHQEQRQVQARVTELEAQLKaeqqKT 589
Cdd:PRK03918   543 SLKKELE-KLEELKKKLAELEKKLDE-------LEEELAELLKELEEL------GFESVEELEERLKELEPFYN----EY 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  590 TEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQcratemEAESRSLMEQREREQKELEQEKAGRKGL 669
Cdd:PRK03918   605 LELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE------ELEKKYSEEEYEELREEYLELSRELAGL 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  670 EARIQQLEEaHQAETEALRHELAEATASQHRAESECERLirevESRQKRFEARQQEEARYGAMFQEQLMalkgektgQEV 749
Cdd:PRK03918   679 RAELEELEK-RREEIKKTLEKLKEELEEREKAKKELEKL----EKALERVEELREKVKKYKALLKERAL--------SKV 745

                          650
                   ....*....|
gi 1907176327  750 QEEAVEIHSE 759
Cdd:PRK03918   746 GEIASEIFEE 755
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
337-728 2.61e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 62.48  E-value: 2.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  337 QLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQAsQAQGAQLTAQLTSMTGLNAtL 416
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEEL-EAELEELREELEKLEKLLQ-L 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  417 QQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREA 496
Cdd:COG4717    128 LPLYQELEALEAELAELPER-LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQ 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  497 SLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT-----------SVTQAQQEKAELSQKIGELHACIEASH 565
Cdd:COG4717    207 RLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEArlllliaaallALLGLGGSLLSLILTIAGVLFLVLGLL 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  566 QEQRQVQARVTELEAQLKAEQQKTTEREKVvqEKAQLQEQLRALEESLKITKGSLEEEKRRAADAlkeQQCRATEMEAES 645
Cdd:COG4717    287 ALLFLLLAREKASLGKEAEELQALPALEEL--EEEELEELLAALGLPPDLSPEELLELLDRIEEL---QELLREAEELEE 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  646 RSLMEQREREQKELEQEK--AGRKGLEARIQQLEEAHQAETE--ALRHELAE---------ATASQHRAESECERLIREV 712
Cdd:COG4717    362 ELQLEELEQEIAALLAEAgvEDEEELRAALEQAEEYQELKEEleELEEQLEEllgeleellEALDEEELEEELEELEEEL 441

                          410
                   ....*....|....*.
gi 1907176327  713 ESRQKRFEARQQEEAR 728
Cdd:COG4717    442 EELEEELEELREELAE 457
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
366-985 3.52e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.24  E-value: 3.52e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  366 EKQQLASLIADLQSSVSNLSQAKEELEQASQaqgaqltaQLTSMTGLNATLQQRDQELASLKEQakkEQAQMLQTMQEQE 445
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALEDARE--------QIELLEPIRELAERYAAARERLAEL---EYLRAALRLWFAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  446 QAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQqlaIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQ 525
Cdd:COG4913    288 RRLELLEAELEELRAELARLEAELERLEARLDALREELDE---LEAQIRGNGGDRLEQLEREIERLERELEERERRRARL 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  526 LQAANDARdnaqtsvTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQqktterekvvQEKAQLQEQ 605
Cdd:COG4913    365 EALLAALG-------LPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR----------RELRELEAE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  606 LRALEESlkitKGSLEEEKRRAADALKEqQCRATEME----AEsrsLMEQREREQK------------------ELEQEK 663
Cdd:COG4913    428 IASLERR----KSNIPARLLALRDALAE-ALGLDEAElpfvGE---LIEVRPEEERwrgaiervlggfaltllvPPEHYA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  664 AGRKGLEARiqQLEEAHQAEtealrhELAEATASQHRAESECERLIREVESRQKRFEA--RQQEEARYGAMFQEQLMALK 741
Cdd:COG4913    500 AALRWVNRL--HLRGRLVYE------RVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwlEAELGRRFDYVCVDSPEELR 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  742 GE-----KTGQEVQEEAVEIHSEGQPGQQQSQLAQlhaslaKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKT 816
Cdd:COG4913    572 RHpraitRAGQVKGNGTRHEKDDRRRIRSRYVLGF------DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  817 LVLKAGEQQETASLELLKeppRAANRASDQLGEQQGRpFSSTHAAVKAMEREAEQMGGELERLRAALiksqgqqqeergq 896
Cdd:COG4913    646 RREALQRLAEYSWDEIDV---ASAEREIAELEAELER-LDASSDDLAALEEQLEELEAELEELEEEL------------- 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  897 qerevARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELK 976
Cdd:COG4913    709 -----DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLN 783


                   ....*....
gi 1907176327  977 ELQQTLEQL 985
Cdd:COG4913    784 RAEEELERA 792
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 235-609 4.28e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 61.89  E-value: 4.28e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  235 EFANHLQQLQGAFNDLIEEHSKASqEW----------AEKQARLENELStALQDKkcLEEKNEILQGKLSQLEDQATRLQ 304
Cdd:COG3096    310 EMARELEELSARESDLEQDYQAAS-DHlnlvqtalrqQEKIERYQEDLE-ELTER--LEEQEEVVEEAAEQLAEAEARLE 385

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  305 ESPApekgEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLE-CERGKQEAQLLAER-----SRFEDEKQQLASLIADLQ 378
Cdd:COG3096    386 AAEE----EVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEkARALCGLPDLTPENaedylAAFRAKEQQATEEVLELE 461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  379 SSVSNLSQAKEELEQASQAqgaqltaqLTSMTGlnatlqqrdqelASLKEQAKKEQAQMLQTMQEQEQAAQglrqQVEQL 458
Cdd:COG3096    462 QKLSVADAARRQFEKAYEL--------VCKIAG------------EVERSQAWQTARELLRRYRSQQALAQ----RLQQL 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  459 ssslklkEQQLEEAakEQEATRQDHAQQLAivaEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 538
Cdd:COG3096    518 -------RAQLAEL--EQRLRQQQNAERLL---EEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQ 585

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327  539 SVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEA-------QLKAEQQKTTEREKVVQEKAQLQEQLRAL 609
Cdd:COG3096    586 QLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEvtaamqqLLEREREATVERDELAARKQALESQIERL 663
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 906-1603 5.37e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 61.89  E-value: 5.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  906 QERGQAQADLAQE--KAAKAELEmRLQNTLNEQRVEFAALQEAL-----AHALTEK-----EGTDQELAKLRGQEAAQRT 973
Cdd:COG3096    377 LAEAEARLEAAEEevDSLKSQLA-DYQQALDVQQTRAIQYQQAVqalekARALCGLpdltpENAEDYLAAFRAKEQQATE 455

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  974 ELKELQQTLEQLKI---------QLVKKekehPAGGASGEDASGPGTQS-ETAGKTDAPGPELQALRAEISKLEQQCQQQ 1043
Cdd:COG3096    456 EVLELEQKLSVADAarrqfekayELVCK----IAGEVERSQAWQTARELlRRYRSQQALAQRLQQLRAQLAELEQRLRQQ 531

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1044 QQQV---EGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEW-KAQVAR 1119
Cdd:COG3096    532 QNAErllEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWlAAQDAL 611

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1120 GQQEAERKSSLISSleEEVSILNRQVLEKEGESKELKRLVVaesEKSQKLEERLRLLQVETASNSAR------------- 1186
Cdd:COG3096    612 ERLREQSGEALADS--QEVTAAMQQLLEREREATVERDELA---ARKQALESQIERLSQPGGAEDPRllalaerlggvll 686

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1187 -----------AAERS---------------SALREEVQSL-----------------------REEVEKQRVVSENSRQ 1217
Cdd:COG3096    687 seiyddvtledAPYFSalygparhaivvpdlSAVKEQLAGLedcpedlyliegdpdsfddsvfdAEELEDAVVVKLSDRQ 766

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1218 -------EL-----ASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVsellpAKHLCQQlqaeqaaaekrF 1285
Cdd:COG3096    767 wrysrfpEVplfgrAAREKRLEELRAERDELAEQYAKASFDVQKLQRLHQAFSQFV-----GGHLAVA-----------F 830

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1286 REELEQSKQAaggLQAELMRAQRELgelgslrqkiVEQERAAQQLRAEKASYAEQLSMLKKAHG---LLAEEnrGLGERa 1362
Cdd:COG3096    831 APDPEAELAA---LRQRRSELEREL----------AQHRAQEQQLRQQLDQLKEQLQLLNKLLPqanLLADE--TLADR- 894

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1363 nlgRQFLEVELDQARE--KYVQELAAVRTDAETHLAEMRQEAQStsreLEVMTAKYEGAKvkvleerqrfqEERQKLTAQ 1440
Cdd:COG3096    895 ---LEELREELDAAQEaqAFIQQHGKALAQLEPLVAVLQSDPEQ----FEQLQADYLQAK-----------EQQRRLKQQ 956

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1441 VEQL-EVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQkeqaaehyklqme 1519
Cdd:COG3096    957 IFALsEVVQRRPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLAS------------- 1023

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1520 kAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERlgRELQQAGLKTKeaeQTCRHLTAQVRSLEAQVAHADQQLR 1599
Cdd:COG3096   1024 -LKSSRDAKQQTLQELEQELEELGVQADAEAEERARIRR--DELHEELSQNR---SRRSQLEKQLTRCEAEMDSLQKRLR 1097


                   ....
gi 1907176327 1600 DLGK 1603
Cdd:COG3096   1098 KAER 1101
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1283-1605 9.71e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 9.71e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1283 KRFREELEQSKQAAGGLQAelMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGllaeenrglgera 1362
Cdd:TIGR02168  213 ERYKELKAELRELELALLV--LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS------------- 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1363 nlgrqflevELDQAREKYVQELAAVRTDaethLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVE 1442
Cdd:TIGR02168  278 ---------ELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1443 QLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAK 1522
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1523 THydAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLG 1602
Cdd:TIGR02168  425 EL--LKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502


                   ...
gi 1907176327 1603 KFQ 1605
Cdd:TIGR02168  503 GFS 505
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 417-724 1.62e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 59.75  E-value: 1.62e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  417 QQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDH-AQQLAIVAEARE 495
Cdd:pfam17380  303 QEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEiAMEISRMRELER 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  496 ASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARV 575
Cdd:pfam17380  383 LQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQV 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  576 TELEAQLKAEQQKTTEREKVVQEKAQLQEQLRaleeslKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQRERE 655
Cdd:pfam17380  463 ERLRQQEEERKRKKLELEKEKRDRKRAEEQRR------KILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRR 536

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327  656 qkELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEatasqhrAESECERLIREVESRQKRFEARQQ 724
Cdd:pfam17380  537 --EAEEERRKQQEMEERRRIQEQMRKATEERSRLEAME-------REREMMRQIVESEKARAEYEATTP 596
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1110-1603 1.62e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 59.74  E-value: 1.62e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1110 EEEWKAQVARGQQEAERKSSlissleEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAE 1189
Cdd:pfam05483  103 QKENKLQENRKIIEAQRKAI------QELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEY 176

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1190 RSSALREEVQSLREEVEKQ-------RVVSENSRQELASQAERAEELGQEL-KAWQEKFFQKEQALSALQLEHTSTQALV 1261
Cdd:pfam05483  177 EREETRQVYMDLNNNIEKMilafeelRVQAENARLEMHFKLKEDHEKIQHLeEEYKKEINDKEKQVSLLLIQITEKENKM 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1262 SELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAEL----MRAQRELGELGSLRQKIVEQERAAQQLRAEKASY 1337
Cdd:pfam05483  257 KDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELedikMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQ 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1338 AEQLSMLKKAHGLLAEENRG----LGERANLGRQFLEVELDQarekyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMT 1413
Cdd:pfam05483  337 MEELNKAKAAHSFVVTEFEAttcsLEELLRTEQQRLEKNEDQ-----LKIITMELQKKSSELEEMTKFKNNKEVELEELK 411

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1414 aKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRL 1493
Cdd:pfam05483  412 -KILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIEL 490

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1494 QTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQkenKELRSEAERLGRELQQAGLKTK-- 1571
Cdd:pfam05483  491 TAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKE---MNLRDELESVREEFIQKGDEVKck 567

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1907176327 1572 --EAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1603
Cdd:pfam05483  568 ldKSEENARSIEYEVLKKEKQMKILENKCNNLKK 601
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 416-818 1.67e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 60.19  E-value: 1.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  416 LQQRDQELASLKEQAKKEQAQMLQ-------------TMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEA---T 479
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKElekkhqqlceeknALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESrleE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  480 RQDHAQQLAIVAEAR-------EASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQ 552
Cdd:pfam01576   87 EEERSQQLQNEKKKMqqhiqdlEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTS 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  553 KIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQ----EKAQLQEQ---LRALEESLKITKGSLEEEKR 625
Cdd:pfam01576  167 NLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRklegESTDLQEQiaeLQAQIAELRAQLAKKEEELQ 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  626 RAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEahqaETEALRHELAE---ATASQH--- 699
Cdd:pfam01576  247 AALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGE----ELEALKTELEDtldTTAAQQelr 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  700 -RAESECERLIREVESRQKRFEARQQEEARYGAM----FQEQLMALKG-----EKTGQEVQEEAVEIHSEGQPGQQQSQl 769
Cdd:pfam01576  323 sKREQEVTELKKALEEETRSHEAQLQEMRQKHTQaleeLTEQLEQAKRnkanlEKAKQALESENAELQAELRTLQQAKQ- 401

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 1907176327  770 aQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLV 818
Cdd:pfam01576  402 -DSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLL 449
mukB PRK04863
chromosome partition protein MukB;
349-741 1.82e-08

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 59.97  E-value: 1.82e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  349 RGKQEAQLLAERSRFEDEKQQLAS--LIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNAtLQQRDQELASL 426
Cdd:PRK04863   282 RVHLEEALELRRELYTSRRQLAAEqyRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEK-IERYQADLEEL 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  427 KEQAKkEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLK---------LKEQQLEEAAKEQEATRQDHAQQLAIVAEAREAS 497
Cdd:PRK04863   361 EERLE-EQNEVVEEADEQQEENEARAEAAEEEVDELKsqladyqqaLDVQQTRAIQYQQAVQALERAKQLCGLPDLTADN 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  498 LRERdtaRQQLETVEKEKDAKLESLQQQL---QAANDARDNAQTSVTQA--QQEKAELSQKIGELhaciEASHQEQRQVQ 572
Cdd:PRK04863   440 AEDW---LEEFQAKEQEATEELLSLEQKLsvaQAAHSQFEQAYQLVRKIagEVSRSEAWDVAREL----LRRLREQRHLA 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  573 ARVTELEAQLKaeqqkttEREKVVQEKAQLQEQLRALEESLKITKGSLEEekrrAADALKEQQCRATEMEAESRSLMEQR 652
Cdd:PRK04863   513 EQLQQLRMRLS-------ELEQRLRQQQRAERLLAEFCKRLGKNLDDEDE----LEQLQEELEARLESLSESVSEARERR 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  653 EREQKELEQEKAGRKGLEARIQQLEEAHQA---------ETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQ 723
Cdd:PRK04863   582 MALRQQLEQLQARIQRLAARAPAWLAAQDAlarlreqsgEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEI 661

                          410
                   ....*....|....*...
gi 1907176327  724 QEEARYGAMFQEQLMALK 741
Cdd:PRK04863   662 ERLSQPGGSEDPRLNALA 679
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 454-1253 2.04e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.60  E-value: 2.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  454 QVEQLSSSLKLKEQQLEEAAKEqeatrqdhAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQqlqaANDAR 533
Cdd:pfam02463  143 KIEIIAMMKPERRLEIEEEAAG--------SRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQ----AKKAL 210

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  534 DNAQtsvTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESL 613
Cdd:pfam02463  211 EYYQ---LKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEE 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  614 KITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAE 693
Cdd:pfam02463  288 LKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEK 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  694 ATASQHRAESECERLIREVESRQKRFEarqqeearygamfQEQLMALKGEKTGQEvqeeaveihsegqpgqqQSQLAQLH 773
Cdd:pfam02463  368 LEQLEEELLAKKKLESERLSSAAKLKE-------------EELELKSEEEKEAQL-----------------LLELARQL 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  774 ASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEpprAANRASDQLGEQQGR 853
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL---VKLQEQLELLLSRQK 494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  854 PFSSTHAAVKAMEREA-EQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNT 932
Cdd:pfam02463  495 LEERSQKESKARSGLKvLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELP 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  933 LNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQ 1012
Cdd:pfam02463  575 LGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1013 SETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASA 1092
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1093 QRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEER 1172
Cdd:pfam02463  735 NEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1173 LRLLQVETASNSARAAERSSALREEVQSLrEEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQL 1252
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELK-EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE 893


                   .
gi 1907176327 1253 E 1253
Cdd:pfam02463  894 K 894
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 371-589 2.82e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.24  E-value: 2.82e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  371 ASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQG 450
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  451 LRQQVEQLSSSLKlKEQQLEEAAKEQEATRQDHAQQLAI-------VAEAREASLRERDTARQQLETVEKEKDAKLESLQ 523
Cdd:COG4942     99 LEAQKEELAELLR-ALYRLGRQPPLALLLSPEDFLDAVRrlqylkyLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176327  524 QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKT 589
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
320-882 3.41e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 3.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  320 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSrfEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 399
Cdd:COG4913    256 PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAEL--EELRAELARLEAELERLEARLDALREELDELEAQIR 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  400 AQLTAQLtsmtglnatlqqrdqelaslkEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 479
Cdd:COG4913    334 GNGGDRL---------------------EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  480 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEkdakLESLQQQlqaandardnaQTSVTQAQQE-KAELSQK----- 553
Cdd:COG4913    393 LEALEEELEALEEALAEAEAALRDLRRELRELEAE----IASLERR-----------KSNIPARLLAlRDALAEAlglde 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  554 -----IGELhacIEASHQEQR--------------------QVQARVTELEAQLKAEQQKTTERekvVQEKAQLQEQLRA 608
Cdd:COG4913    458 aelpfVGEL---IEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVNRLHLRGRLVYER---VRTGLPDPERPRL 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  609 LEESL--KIT------KGSLEEEKRRAADALKeqqCR-ATEMEAESRSLMEQREREQKELEQEKAGRKGLEAR------- 672
Cdd:COG4913    532 DPDSLagKLDfkphpfRAWLEAELGRRFDYVC---VDsPEELRRHPRAITRAGQVKGNGTRHEKDDRRRIRSRyvlgfdn 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  673 IQQLeeahqaetEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEarygAMFQEQLMALKGEKTGQEVQEE 752
Cdd:COG4913    609 RAKL--------AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLA----EYSWDEIDVASAEREIAELEAE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  753 AVEIHSEgqpgqqQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLEL 832
Cdd:COG4913    677 LERLDAS------SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL 750

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176327  833 LKEppRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQmggELERLRAA 882
Cdd:COG4913    751 LEE--RFAAALGDAVERELRENLEERIDALRARLNRAEE---ELERAMRA 795
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 240-717 3.51e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.98  E-value: 3.51e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  240 LQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEK----NEILQGKLSQLEDQATRLQES--------- 306
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQarnqNSMYMRQLSDLESTVSQLRSElreakrmye 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  307 ---PAPEKGEVLGDAlQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERS---RFEDEKQQLASLIADLQSS 380
Cdd:pfam15921  342 dkiEELEKQLVLANS-ELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEqnkRLWDRDTGNSITIDHLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  381 VSNLSQAKEELEQ-----ASQAQGaQLTAQLTSMTGLNATLQQRDQELASLkEQAKKEQAQMLQTMQEQEQAAQGLRQQV 455
Cdd:pfam15921  421 LDDRNMEVQRLEAllkamKSECQG-QMERQMAAIQGKNESLEKVSSLTAQL-ESTKEMLRKVVEELTAKKMTLESSERTV 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  456 EQLSSSLKLKEQQLEEAAKE--QEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDAR 533
Cdd:pfam15921  499 SDLTASLQEKERAIEATNAEitKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLV 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  534 DNAQTSVTQAQQEKAELSQKIG-------ELHACIEASHQEQRQVQARVTELEAQ-----------LKAEQQKTTEREKV 595
Cdd:pfam15921  579 GQHGRTAGAMQVEKAQLEKEINdrrlelqEFKILKDKKDAKIRELEARVSDLELEkvklvnagserLRAVKDIKQERDQL 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  596 VQEKAQLQEQLRALEESLKITKGSLE---EEKRRAADALKEQQCRATEMEAESRSLMEQRERE-----------QKELEQ 661
Cdd:pfam15921  659 LNEVKTSRNELNSLSEDYEVLKRNFRnksEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgmQKQITA 738

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176327  662 EKAGRKGLEARIQQLEEAH----------QAETEALRHELAEATASQHRAESECErLIREVESRQK 717
Cdd:pfam15921  739 KRGQIDALQSKIQFLEEAMtnankekhflKEEKNKLSQELSTVATEKNKMAGELE-VLRSQERRLK 803
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1425-1635 4.15e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 4.15e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1425 EERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQL 1504
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1505 SQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGL----KTKEAEQTCRHL 1580
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLEtlrsKVAQLELQIASL 398

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327 1581 TAQVRSLEAQVAHADQQLRDLGkfQVATDALKSREPQVKPQLDLSIDSLDLSLEE 1635
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQ--QEIEELLKKLEEAELKELQAELEELEEELEE 451
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1025-1558 6.69e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.77  E-value: 6.69e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1025 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALEtlqgQLEEKARELGHNQAaSASAQRELQALRAKAQ 1104
Cdd:PRK03918   232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE----ELEEKVKELKELKE-KAEEYIKLSEFYEEYL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1105 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSilnrqvlEKEGESKELKRlVVAESEKSQKLEERLRLLQVETASNS 1184
Cdd:PRK03918   307 DELREIEKRLSRLEEEINGIEERIKELEEKEERLE-------ELKKKLKELEK-RLEELEERHELYEEAKAKKEELERLK 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1185 ARAAERSSalrEEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALvsEL 1264
Cdd:PRK03918   379 KRLTGLTP---EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRK--EL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1265 LPAKHLcqqLQAEQAAAEKRFREELEQSKQAAGGLQAELMRaQRELGELGSLRQKIVEQERAAQQLRAEKASY-AEQLSM 1343
Cdd:PRK03918   454 LEEYTA---ELKRIEKELKEIEEKERKLRKELRELEKVLKK-ESELIKLKELAEQLKELEEKLKKYNLEELEKkAEEYEK 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1344 LKKAHGLLAEENRGLGERANLGRQF------LEVELDQAREkyvqELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYE 1417
Cdd:PRK03918   530 LKEKLIKLKGEIKSLKKELEKLEELkkklaeLEKKLDELEE----ELAELLKELEELGFESVEELEERLKELEPFYNEYL 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1418 GAKvKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQasKVQQQKLKAFQAQRGESQQEVQRLQTQL 1497
Cdd:PRK03918   606 ELK-DAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK--KYSEEEYEELREEYLELSRELAGLRAEL 682

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176327 1498 NELQAQLSQKEQAAEHYKLQMEKAKThydaKKQQNQKLQEQLQDLEELQKENKELRSEAER 1558
Cdd:PRK03918   683 EELEKRREEIKKTLEKLKEELEEREK----AKKELEKLEKALERVEELREKVKKYKALLKE 739
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 182-606 7.83e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.72  E-value: 7.83e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  182 SELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGD----LSFKVREFANHLQQLQGAFNDLIEEHSKA 257
Cdd:TIGR04523  218 SQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKikkqLSEKQKELEQNNKKIKELEKQLNQLKSEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  258 SQEWAEKQARLENELSTAL--QDKKCLEEKNEILQG--KLSQLEDQATRLQ------ESPAPEKGEVLGDAL-QLDTLKQ 326
Cdd:TIGR04523  298 SDLNNQKEQDWNKELKSELknQEKKLEEIQNQISQNnkIISQLNEQISQLKkeltnsESENSEKQRELEEKQnEIEKLKK 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  327 EAAKLATDNTQLQTRVETLECERGKQEAQ----------LLAERSRFEDEKQQLASLIADLQSSVSNLSQAK-------E 389
Cdd:TIGR04523  378 ENQSYKQEIKNLESQINDLESKIQNQEKLnqqkdeqikkLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDsvkeliiK 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  390 ELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELaslkeqakKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQL 469
Cdd:TIGR04523  458 NLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL--------KSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  470 EEAAKEQEatrqdhaqqLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 549
Cdd:TIGR04523  530 ESEKKEKE---------SKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKD 600

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176327  550 LSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKtteREKVVQEKAQLQEQL 606
Cdd:TIGR04523  601 LIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSK---KNKLKQEVKQIKETI 654
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1025-1503 8.08e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.62  E-value: 8.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1025 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERacRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1104
Cdd:COG4913    256 PIRELAERYAAARERLAELEYLRAALRLWFAQRR--LELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIR 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1105 DHS-KAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASN 1183
Cdd:COG4913    334 GNGgDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1184 SARAAERSSALREEVQSLREeveKQRVVSENS---RQELASQAERAE----------ELGQELKAWQ------------- 1237
Cdd:COG4913    414 LRDLRRELRELEAEIASLER---RKSNIPARLlalRDALAEALGLDEaelpfvgeliEVRPEEERWRgaiervlggfalt 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1238 ----EKFFQkeQALSALQLEHTSTQaLVSELLPAKHlcqQLQAEQAAAEKRFREELEQSKQAAGG-LQAEL--------- 1303
Cdd:COG4913    491 llvpPEHYA--AALRWVNRLHLRGR-LVYERVRTGL---PDPERPRLDPDSLAGKLDFKPHPFRAwLEAELgrrfdyvcv 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1304 ------------------MRAQRELGELG-------------SLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLA 1352
Cdd:COG4913    565 dspeelrrhpraitragqVKGNGTRHEKDdrrrirsryvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQ 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1353 EENRGLGERANLgrQFLEVELDQAREKYV---QELAAVRTD------AETHLAEMRQEAQSTSRELEVMTAKYEGAKvkv 1423
Cdd:COG4913    645 ERREALQRLAEY--SWDEIDVASAEREIAeleAELERLDASsddlaaLEEQLEELEAELEELEEELDELKGEIGRLE--- 719

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1424 lEERQRFQEERQKLTAQVEQLEvfQREQTKQVEELSKKLTEHDQAsKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQ 1503
Cdd:COG4913    720 -KELEQAEEELDELQDRLEAAE--DLARLELRALLEERFAAALGD-AVERELRENLEERIDALRARLNRAEEELERAMRA 795
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1053-1588 9.88e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.38  E-value: 9.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1053 SLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHskaeEEWKAQVARGQQEAERKSSLIS 1132
Cdd:PRK03918   180 RLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL----EELKEEIEELEKELESLEGSKR 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1133 SLEEEVSILNRQVLEKEGESKELKRLV--VAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEkqrv 1210
Cdd:PRK03918   256 KLEEKIRELEERIEELKKEIEELEEKVkeLKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK---- 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1211 vsensrqELASQAERAEELGQELKAWQEKffqkeqaLSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELE 1290
Cdd:PRK03918   332 -------ELEEKEERLEELKKKLKELEKR-------LEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1291 QSKQaagglqaELMRAQREL-GELGSLRQKIVEQERAAQQLRAEK-------------------ASYAEQLSMLKKAHGL 1350
Cdd:PRK03918   398 KAKE-------EIEEEISKItARIGELKKEIKELKKAIEELKKAKgkcpvcgrelteehrkellEEYTAELKRIEKELKE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1351 LAEENRGLGERANLGRQFLEVELDQAREKYV-QELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQR 1429
Cdd:PRK03918   471 IEEKERKLRKELRELEKVLKKESELIKLKELaEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1430 FQEERQKLTAQVEQLEVFQREQT-----------KQVEELSKKLTEHDQASKvQQQKLKAFQAQRGESQQEVQRLQTQLN 1498
Cdd:PRK03918   551 LEELKKKLAELEKKLDELEEELAellkeleelgfESVEELEERLKELEPFYN-EYLELKDAEKELEREEKELKKLEEELD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1499 ELQAQLSQKEQAAEHYKLQMEKAKTHYDAKkqqnqklqeqlqDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCR 1578
Cdd:PRK03918   630 KAFEELAETEKRLEELRKELEELEKKYSEE------------EYEELREEYLELSRELAGLRAELEELEKRREEIKKTLE 697

                          570
                   ....*....|
gi 1907176327 1579 HLTAQVRSLE 1588
Cdd:PRK03918   698 KLKEELEERE 707
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
706-1239 1.11e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.36  E-value: 1.11e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  706 ERLIREVESRQKRFEArqQEEARYGAMFQEQLMALKgektgQEVQEEAVEI-HSEGQPGQQQSQLAQLHASLAKAIQQVQ 784
Cdd:PRK02224   179 ERVLSDQRGSLDQLKA--QIEEKEEKDLHERLNGLE-----SELAELDEEIeRYEEQREQARETRDEADEVLEEHEERRE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  785 EKEVraqkLVDDLSALQEKMAATNKEVACLKTLVlkagEQQETASLELLKEppRAANRASDQLGEQQGrpfSSTHAAVKA 864
Cdd:PRK02224   252 ELET----LEAEIEDLRETIAETEREREELAEEV----RDLRERLEELEEE--RDDLLAEAGLDDADA---EAVEARREE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  865 MEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRlQNTLNEQRVEFAALQ 944
Cdd:PRK02224   319 LEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDR-REEIEELEEEIEELR 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  945 EALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAG-----GASGEDASGPGTQSETAGKT 1019
Cdd:PRK02224   398 ERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGkcpecGQPVEGSPHVETIEEDRERV 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1020 DAPGPELQALRAEISKLEqqcqqqqqqveglthslksERACRAEQDKALETLQGQLEEKAR---ELGHNQAASASAQRE- 1095
Cdd:PRK02224   478 EELEAELEDLEEEVEEVE-------------------ERLERAEDLVEAEDRIERLEERREdleELIAERRETIEEKREr 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1096 LQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEvsilnRQVLEKEGESKELKRLVVAESEKSQKLEERLRL 1175
Cdd:PRK02224   539 AEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK-----LAELKERIESLERIRTLLAAIADAEDEIERLRE 613

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176327 1176 LQVETASNSARAAERSSALREEVQSLREEVEKQRVvsENSRQELASQAERAEELGQELKAWQEK 1239
Cdd:PRK02224   614 KREALAELNDERRERLAEKRERKRELEAEFDEARI--EEAREDKERAEEYLEQVEEKLDELREE 675
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 213-583 1.19e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.19e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  213 SQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGK 292
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  293 LSQLEDQATRLQESpAPEKGEVLGDALQ-LDTLKQEAAKLATDNT-QLQTRVETLECERGKQEAQLLAErsrfEDEKQQL 370
Cdd:TIGR02169  246 LASLEEELEKLTEE-ISELEKRLEEIEQlLEELNKKIKDLGEEEQlRVKEKIGELEAEIASLERSIAEK----ERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  371 ASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAqltsmtgLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQG 450
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDK-------LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  451 LRQQVEQLsSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKekdaKLESLQQQLQAAN 530
Cdd:TIGR02169  394 LEKLKREI-NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW----KLEQLAADLSKYE 468

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176327  531 DARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLK 583
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQ 521
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1428-1650 1.41e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.99  E-value: 1.41e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1428 QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQK 1507
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1508 EQAAEHYKLQMEKAKTHYDAK----KQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQ 1583
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELeaqlEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176327 1584 VRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEEGTPCSVASKLPRTQP 1650
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEE 447
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 160-725 1.55e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 56.72  E-value: 1.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  160 MQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKIS----QLSEENGDLSFKVRE 235
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAarkqELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  236 FANHLQQLQGafndlieEHSKASQEWAEKQARLENELSTALQ---DKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKG 312
Cdd:pfam01576   87 EEERSQQLQN-------EKKKMQQHIQDLEEQLDEEEAARQKlqlEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  313 EVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQllaeRSRFEDEKQQLASLIADLQSSVSNLSQAKEELE 392
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG----RQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  393 QASQAQGAQLTAQLTSM---TGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkEQQL 469
Cdd:pfam01576  236 AQLAKKEEELQAALARLeeeTAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL---EDTL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  470 EEAAKEQEAtrqdHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 549
Cdd:pfam01576  313 DTTAAQQEL----RSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  550 LSQKIGELHACIEASHQEQRQVQARVTELEAQL-KAEQQKTTEREKVVQEKAQLQEQLRALEE----SLKITK--GSLEE 622
Cdd:pfam01576  389 LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLsESERQRAELAEKLSKLQSELESVSSLLNEaegkNIKLSKdvSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  623 EKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLeeahQAETEALRHELAEATASQHRAE 702
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTL----QAQLSDMKKKLEEDAGTLEALE 544

                          570       580
                   ....*....|....*....|...
gi 1907176327  703 SECERLIREVESRQKRFEARQQE 725
Cdd:pfam01576  545 EGKKRLQRELEALTQQLEEKAAA 567
mukB PRK04863
chromosome partition protein MukB;
236-582 2.36e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 56.50  E-value: 2.36e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  236 FANHLQQLQGAFNDL---IEEHSKASQEWAEKQARLENELSTALQDKKCLEekneilqgklSQLEDQATRLqespapekg 312
Cdd:PRK04863   346 QQEKIERYQADLEELeerLEEQNEVVEEADEQQEENEARAEAAEEEVDELK----------SQLADYQQAL--------- 406

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  313 evlgDALQLDTLKQEAAKLATDNTQLQTRVETLECErgkqeaQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELE 392
Cdd:PRK04863   407 ----DVQQTRAIQYQQAVQALERAKQLCGLPDLTAD------NAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFE 476

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  393 QASQAQ---GAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQL 469
Cdd:PRK04863   477 QAYQLVrkiAGEVSRSEAWDVARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDEL 556

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  470 EEAAKEQEATRQDHAQQLAIVAEAREaslrerdTARQQLETVeKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAE 549
Cdd:PRK04863   557 EQLQEELEARLESLSESVSEARERRM-------ALRQQLEQL-QARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQD 628

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1907176327  550 LSQKIGELHACIEASHQEQRQVQARVTELEAQL 582
Cdd:PRK04863   629 VTEYMQQLLERERELTVERDELAARKQALDEEI 661
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 180-816 2.96e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 55.82  E-value: 2.96e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  180 EPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREfanhlqqlqgAFNDLIEEHSKASQ 259
Cdd:TIGR00606  246 ELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE----------QLNDLYHNHQRTVR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  260 EWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQ--LDTLKQEAAKLATDNTQ 337
Cdd:TIGR00606  316 EKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRleLDGFERGPFSERQIKNF 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  338 LQTRVETLEcERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQ 417
Cdd:TIGR00606  396 HTLVIERQE-DEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  418 QRDQEL-ASLKEQAKKEQAQMLQTMQEQEQAaqgLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQdhaqqlaivaeaREA 496
Cdd:TIGR00606  475 ELDQELrKAERELSKAEKNSLTETLKKEVKS---LQNEKADLDRKLRKLDQEMEQLNHHTTTRTQ------------MEM 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  497 SLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDnaqtSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVT 576
Cdd:TIGR00606  540 LTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLED----WLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  577 ELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLK----ITKGSLEEEKRRAADALKEQQC-----RATEMEAESRS 647
Cdd:TIGR00606  616 SKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKqramLAGATAVYSQFITQLTDENQSCcpvcqRVFQTEAELQE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  648 LMEQRER-------EQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFE 720
Cdd:TIGR00606  696 FISDLQSklrlapdKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLG 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  721 ARQQEEarygamfQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSAL 800
Cdd:TIGR00606  776 TIMPEE-------ESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELN 848

                          650
                   ....*....|....*.
gi 1907176327  801 QEKMAATNKEVACLKT 816
Cdd:TIGR00606  849 RKLIQDQQEQIQHLKS 864
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 341-683 3.06e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.11  E-value: 3.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  341 RVETLECERGKQEAQLLAERSRFEDEKQQLA-------SLIADLQSSVSNLS--------QAK--------EELEQASQA 397
Cdd:COG3096    286 RALELRRELFGARRQLAEEQYRLVEMARELEelsaresDLEQDYQAASDHLNlvqtalrqQEKieryqedlEELTERLEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  398 QGAQLTAQLTSMTGLNATLQQRDQELASLKEQ-AKKEQA-QMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEE---- 471
Cdd:COG3096    366 QEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQlADYQQAlDVQQTRAIQYQQAVQALEKARALCGLPDLTPENAEDylaa 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  472 -AAKEQEATRQ--DHAQQLAIVAEAReaslRERDTARQQLETV--EKEKDAKLESLQQQLQAANDARDNAQTsVTQAQQE 546
Cdd:COG3096    446 fRAKEQQATEEvlELEQKLSVADAAR----RQFEKAYELVCKIagEVERSQAWQTARELLRRYRSQQALAQR-LQQLRAQ 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  547 KAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRR 626
Cdd:COG3096    521 LAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAAR 600

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  627 A------ADALKEQQCRATEMEAESRSLME------QREREQKELEQEKAGRKG-LEARIQQLEEAHQAE 683
Cdd:COG3096    601 ApawlaaQDALERLREQSGEALADSQEVTAamqqllEREREATVERDELAARKQaLESQIERLSQPGGAE 670
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 284-501 3.43e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 3.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  284 EKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRF 363
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  364 EDEKQQLASLIADLQS-----------SVSNLSQAK------EELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASL 426
Cdd:COG4942    100 EAQKEELAELLRALYRlgrqpplalllSPEDFLDAVrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327  427 KEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRER 501
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGK 254
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1295-1521 4.08e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.38  E-value: 4.08e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1295 AAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELD 1374
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-ELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1375 QAREKYVQELAAVRTDaethLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQ 1454
Cdd:COG4942     90 KEIAELRAELEAQKEE----LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAAL 165

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176327 1455 VEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKA 1521
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
mukB PRK04863
chromosome partition protein MukB;
1312-1603 4.18e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 55.35  E-value: 4.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1312 ELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLaeeNRGLGERANLGRQFLEVELDQARE---------KYVQ 1382
Cdd:PRK04863   838 ELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSAL---NRLLPRLNLLADETLADRVEEIREqldeaeeakRFVQ 914

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1383 ELAAVRTDAETHLAEMRQEAQstsrELEVMTAKYEGAkvkvleerqrfQEERQKLTAQVEQL-EVFQREQTKQVEELSKK 1461
Cdd:PRK04863   915 QHGNALAQLEPIVSVLQSDPE----QFEQLKQDYQQA-----------QQTQRDAKQQAFALtEVVQRRAHFSYEDAAEM 979

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1462 LTEHDQASKVQQQKLKAFQAQRgesqqevQRLQTQLNELQAQLSQKEQAaehyklqMEKAKTHYDAKKQQNQKLQEQLQD 1541
Cdd:PRK04863   980 LAKNSDLNEKLRQRLEQAEQER-------TRAREQLRQAQAQLAQYNQV-------LASLKSSYDAKRQMLQELKQELQD 1045

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176327 1542 LEELQKENKELRSEAERlgRELQQAglkTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1603
Cdd:PRK04863  1046 LGVPADSGAEERARARR--DELHAR---LSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLER 1102
mukB PRK04863
chromosome partition protein MukB;
337-728 4.21e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 55.35  E-value: 4.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  337 QLQTRVETLECERGKQEAQLLAERSRFEDEKQQLaSLIADLQSSVSNLS---------QAKEELEQASQAQG--AQLTAQ 405
Cdd:PRK04863   841 QLNRRRVELERALADHESQEQQQRSQLEQAKEGL-SALNRLLPRLNLLAdetladrveEIREQLDEAEEAKRfvQQHGNA 919

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  406 LTSMTGLNATLQQRDQELASLKEQAKKEQaQMLQTMQEQEQAAQGLRQQVEQLSSSLKlkEQQLEEAAKEQEATRQDHAQ 485
Cdd:PRK04863   920 LAQLEPIVSVLQSDPEQFEQLKQDYQQAQ-QTQRDAKQQAFALTEVVQRRAHFSYEDA--AEMLAKNSDLNEKLRQRLEQ 996

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  486 qlaivAEAreaslrERDTARQQLetveKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSqkigeLHACIEAsh 565
Cdd:PRK04863   997 -----AEQ------ERTRAREQL----RQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLG-----VPADSGA-- 1054

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  566 qeQRQVQARVTELEAQLKAEQQKTTEREKVVQ----EKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEM 641
Cdd:PRK04863  1055 --EERARARRDELHARLSANRSRRNQLEKQLTfceaEMDNLTKKLRKLERDYHEMREQVVNAKAGWCAVLRLVKDNGVER 1132

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  642 EAESR-----SLMEQREREQKELEQEKAGRKGLEARIQQL---EEAHQAET-------------EALRHELAEAT---AS 697
Cdd:PRK04863  1133 RLHRRelaylSADELRSMSDKALGALRLAVADNEHLRDVLrlsEDPKRPERkvqfyiavyqhlrERIRQDIIRTDdpvEA 1212

                          410       420       430
                   ....*....|....*....|....*....|.
gi 1907176327  698 QHRAESECERLIREVESRQKRFEARQQEEAR 728
Cdd:PRK04863  1213 IEQMEIELSRLTEELTSREQKLAISSESVAN 1243
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1426-1601 4.23e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.33  E-value: 4.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1426 ERQRFQEER-QKLTAQVEQLEVFQ-----REQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNE 1499
Cdd:COG1196    206 ERQAEKAERyRELKEELKELEAELlllklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1500 LQAQLSQKEQAAEhyklQMEKAKTHYDAKKQQNQKLQEQLQ-DLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCR 1578
Cdd:COG1196    286 AQAEEYELLAELA----RLEQDIARLEERRRELEERLEELEeELAELEEELEELEEELEELEEELEEAEEELEEAEAELA 361

                          170       180
                   ....*....|....*....|...
gi 1907176327 1579 HLTAQVRSLEAQVAHADQQLRDL 1601
Cdd:COG1196    362 EAEEALLEAEAELAEAEEELEEL 384
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 170-772 5.57e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 54.73  E-value: 5.57e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  170 LNEKQAASSQEPSELEELRGKNESLTVRLHETLKQ--------------CQNLKTEKSQMDRKISQLSEENGDLSFKVRE 235
Cdd:pfam05483  108 LQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQEnkdlikennatrhlCNLLKETCARSAEKTKKYEYEREETRQVYMD 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  236 FANHLQQLQGAFNDL--------IEEHSKASQEWaEKQARLENELSTALQDKKCL-----------EEKNEILQGKLSQL 296
Cdd:pfam05483  188 LNNNIEKMILAFEELrvqaenarLEMHFKLKEDH-EKIQHLEEEYKKEINDKEKQvsllliqitekENKMKDLTFLLEES 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  297 EDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIAD 376
Cdd:pfam05483  267 RDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAA 346

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  377 LQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQM--LQTMQEQEQAAQGLRQQ 454
Cdd:pfam05483  347 HSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELeeLKKILAEDEKLLDEKKQ 426

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  455 VEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLET----------------------VE 512
Cdd:pfam05483  427 FEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKeklknieltahcdklllenkelTQ 506

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  513 KEKDAKLESLQQQLQAANDAR---------DNAQTSVTQAQQE----KAELSQKIGELHACIEASHQEQRQVQARVTELE 579
Cdd:pfam05483  507 EASDMTLELKKHQEDIINCKKqeermlkqiENLEEKEMNLRDElesvREEFIQKGDEVKCKLDKSEENARSIEYEVLKKE 586

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  580 AQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKitKGSLEEEKRRAADALKEQQCRaTEMEAESRSLMEQREREQKEL 659
Cdd:pfam05483  587 KQMKILENKCNNLKKQIENKNKNIEELHQENKALK--KKGSAENKQLNAYEIKVNKLE-LELASAKQKFEEIIDNYQKEI 663

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  660 EQEKAGRKGLearIQQLEEAHQAETEALR----------HELAEATASQHRAESECERLIREVESRQKRFEARQQEEARY 729
Cdd:pfam05483  664 EDKKISEEKL---LEEVEKAKAIADEAVKlqkeidkrcqHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSA 740

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|...
gi 1907176327  730 GAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQL 772
Cdd:pfam05483  741 KAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAIL 783
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 279-821 6.65e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.59  E-value: 6.65e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  279 KKCLEEKNEILQGKLSQLEDQATRLQESPAPEKgEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECE---------- 348
Cdd:TIGR00618  207 TLCTPCMPDTYHERKQVLEKELKHLREALQQTQ-QSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQeavleetqer 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  349 --RGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASL 426
Cdd:TIGR00618  286 inRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVAT 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  427 KEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQ 506
Cdd:TIGR00618  366 SIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAA 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  507 QLETVEKEKDAKlESLQQQLQAANDARdnaqtsvTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQ 586
Cdd:TIGR00618  446 AITCTAQCEKLE-KIHLQESAQSLKER-------EQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPAR 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  587 QKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEE-KRRAADALKEQQCRATEMEAESR--SLMEQREREQKELEQ-E 662
Cdd:TIGR00618  518 QDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSErKQRASLKEQMQEIQQSFSILTQCdnRSKEDIPNLQNITVRlQ 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  663 KAGRKGLEARIQQLEEAHqAETEALRHELAEATASQHRAESEcERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKG 742
Cdd:TIGR00618  598 DLTEKLSEAEDMLACEQH-ALLRKLQPEQDLQDVRLHLQQCS-QELALKLTALHALQLTLTQERVREHALSIRVLPKELL 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  743 EKTGQEVQEEAVEIHSEGQP----GQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLV 818
Cdd:TIGR00618  676 ASRQLALQKMQSEKEQLTYWkemlAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTV 755


                   ...
gi 1907176327  819 LKA 821
Cdd:TIGR00618  756 LKA 758
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 399-630 7.02e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 7.02e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  399 GAQLTAQLTSMTGLNATLQQRDQELASLK---EQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKE 475
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEkelAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  476 QEATRQDHAQQLAIVAEAREASLRERDTARQQLeTVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIG 555
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRQPPLAL-LLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327  556 ELHACIEASHQEQRQVQARvteLEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADA 630
Cdd:COG4942    171 AERAELEALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1094-1574 7.41e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 7.41e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1094 RELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLE------------------------EEVSILNRQVLEKE 1149
Cdd:PRK03918   172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISselpelreeleklekevkeleelkEEIEELEKELESLE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1150 GESKELKRLVVAESEKSQKLEERLRLLQ-----VETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAE 1224
Cdd:PRK03918   252 GSKRKLEEKIRELEERIEELKKEIEELEekvkeLKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1225 RAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQaagglqaELM 1304
Cdd:PRK03918   332 ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKE-------EIE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1305 RAQREL-GELGSLRQKIVEQERAAQQLRAEK-------------------ASYAEQLSMLKKAHGLLAEENRGLGERANL 1364
Cdd:PRK03918   405 EEISKItARIGELKKEIKELKKAIEELKKAKgkcpvcgrelteehrkellEEYTAELKRIEKELKEIEEKERKLRKELRE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1365 GRQFLEVELDQAREKYV-QELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQ 1443
Cdd:PRK03918   485 LEKVLKKESELIKLKELaEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKK 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1444 LEVFQREQT-----------KQVEELSKKLTEHDQASKvQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAE 1512
Cdd:PRK03918   565 LDELEEELAellkeleelgfESVEELEERLKELEPFYN-EYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLE 643

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176327 1513 HYKLQMEKAKTHYDAKKQQN-----QKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAE 1574
Cdd:PRK03918   644 ELRKELEELEKKYSEEEYEElreeyLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAK 710
46 PHA02562
endonuclease subunit; Provisional
 213-475 7.64e-07

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 54.25  E-value: 7.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  213 SQMDR----KISQLSEENGDLSFKVrefaNHLQQLQGAFNDLIEE-HSKASQEWAEKQARLENELSTALQDKKCLEEKNE 287
Cdd:PHA02562   166 SEMDKlnkdKIRELNQQIQTLDMKI----DHIQQQIKTYNKNIEEqRKKNGENIARKQNKYDELVEEAKTIKAEIEELTD 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  288 ILQGKLSQLEDQATRLQEspapekgevlgdalqldtLKQEAAKLATDNTQLQTRVETLE----CERGKQeaQLLAERSRF 363
Cdd:PHA02562   242 ELLNLVMDIEDPSAALNK------------------LNTAAAKIKSKIEQFQKVIKMYEkggvCPTCTQ--QISEGPDRI 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  364 EDEKQQlaslIADLQSSVSNLSQAKEELEQasqaQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMlqtmqE 443
Cdd:PHA02562   302 TKIKDK----LKELQHSLEKLDTAIDELEE----IMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAI-----E 368

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1907176327  444 QEQAAQGLR-QQVEQLSSSLKLKEQQLEEAAKE 475
Cdd:PHA02562   369 ELQAEFVDNaEELAKLQDELDKIVKTKSELVKE 401
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 251-998 1.03e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.21  E-value: 1.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  251 IEEHSKASQEWAEKQARLENELSTALQDKKCL-EEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAA 329
Cdd:pfam02463  158 IEEEAAGSRLKRKKKEALKKLIEETENLAELIiDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEE 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  330 KLATDNTQLQTRVETLECERGKQEAQllAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQasqaQGAQLTAQLTSM 409
Cdd:pfam02463  238 RIDLLQELLRDEQEEIESSKQEIEKE--EEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK----SELLKLERRKVD 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  410 TGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEaakEQEATRQDHAQQLAI 489
Cdd:pfam02463  312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEE---ELLAKKKLESERLSS 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  490 VAEAREASLRERDTARQQLETvEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQR 569
Cdd:pfam02463  389 AAKLKEEELELKSEEEKEAQL-LLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELEL 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  570 QvQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLM 649
Cdd:pfam02463  468 K-KSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAIS 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  650 EQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEAtasQHRAESECERLIREVESRQKRFEARQQEEARY 729
Cdd:pfam02463  547 TAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPL---KSIAVLEIDPILNLAQLDKATLEADEDDKRAK 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  730 GAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNK 809
Cdd:pfam02463  624 VVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKK 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  810 EVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPFS-STHAAVKAMEREAEQMGGELERLRAALIKSQG 888
Cdd:pfam02463  704 KEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEeEEKSRLKKEEKEEEKSELSLKEKELAEEREKT 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  889 QQQEERGQQEREVARLTQERGQAQADLaQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQE 968
Cdd:pfam02463  784 EKLKVEEEKEEKLKAQEEELRALEEEL-KEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE 862

                          730       740       750
                   ....*....|....*....|....*....|
gi 1907176327  969 AAQRTELKELQQTLEQLKIQLVKKEKEHPA 998
Cdd:pfam02463  863 ITKEELLQELLLKEEELEEQKLKDELESKE 892
PRK11281 PRK11281
mechanosensitive channel MscK;
320-620 1.04e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 54.15  E-value: 1.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  320 QLDTLKQEAAKLATDNTQLQTRVETLEC--ERGKQEAQLLAERSRFEDEKQQLASLIADLQS-SVSNLSQAKEELEQASQ 396
Cdd:PRK11281    44 QLDALNKQKLLEAEDKLVQQDLEQTLALldKIDRQKEETEQLKQQLAQAPAKLRQAQAELEAlKDDNDEETRETLSTLSL 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  397 AQ-GAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQM---LQTMQEQEQAAQGLRQQVEQLSSSLKLK---EQQL 469
Cdd:PRK11281   124 RQlESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALyanSQRLQQIRNLLKGGKVGGKALRPSQRVLlqaEQAL 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  470 EEAAKEQEATRQDHAQQLAIVAEAReaslRERDTARQQLetvekekdakLESLQQQLQAANDARDNAQTSVTQAQQEKAE 549
Cdd:PRK11281   204 LNAQNDLQRKSLEGNTQLQDLLQKQ----RDYLTARIQR----------LEHQLQLLQEAINSKRLTLSEKTVQEAQSQD 269

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327  550 LSQKIGE---LHACIEASHQ-EQRQVQArvTELEAQLKAEQQKTtereKVVQEKAQlQEQlRALEESLKITKGSL 620
Cdd:PRK11281   270 EAARIQAnplVAQELEINLQlSQRLLKA--TEKLNTLTQQNLRV----KNWLDRLT-QSE-RNIKEQISVLKGSL 336
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
315-548 1.13e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.87  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  315 LGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSR-----FEDEKQQLASLIADLQSSvsnLSQAKE 389
Cdd:COG3206    157 LAEAYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKnglvdLSEEAKLLLQQLSELESQ---LAEARA 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  390 ELEQAsQAQGAQLTAQLTSMTGLNATLQQrDQELASLKEQ---AKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKE 466
Cdd:COG3206    234 ELAEA-EARLAALRAQLGSGPDALPELLQ-SPVIQQLRAQlaeLEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  467 QQLEEAAKEQEAtrqdhaqqlaiVAEAREASLRER-DTARQQLETVeKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQ 545
Cdd:COG3206    312 QRILASLEAELE-----------ALQAREASLQAQlAQLEARLAEL-PELEAELRRLEREVEVARELYESLLQRLEEARL 379


                   ...
gi 1907176327  546 EKA 548
Cdd:COG3206    380 AEA 382
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 183-660 1.47e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 53.64  E-value: 1.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  183 ELEELRGKNESltvRLHETLKQCQNLKTEKSQMDRKI----SQLSEENG---DLSFKVREFANHLQQLQGAFNDLIEEHS 255
Cdd:pfam01576   72 ELEEILHELES---RLEEEEERSQQLQNEKKKMQQHIqdleEQLDEEEAarqKLQLEKVTTEAKIKKLEEDILLLEDQNS 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  256 KASQEWAEKQARLeNELSTALQDKkclEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDN 335
Cdd:pfam01576  149 KLSKERKLLEERI-SEFTSNLAEE---EEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQI 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  336 TQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGA-------------QL 402
Cdd:pfam01576  225 AELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKaekqrrdlgeeleAL 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  403 TAQLTSMTGLNATLQ----QRDQELASLK----EQAKKEQAQMLQTMQEQEQAAQGLRQQVEQlsssLKLKEQQLEEAAK 474
Cdd:pfam01576  305 KTELEDTLDTTAAQQelrsKREQEVTELKkaleEETRSHEAQLQEMRQKHTQALEELTEQLEQ----AKRNKANLEKAKQ 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  475 EQEATRQDHAQQLAIVAEAREASLRERDTARQQL----------ETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQ 544
Cdd:pfam01576  381 ALESENAELQAELRTLQQAKQDSEHKRKKLEGQLqelqarlsesERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLS 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  545 QEKAELSQKIGELHACIEASHQEQRQVQARVTELEA-------QLKAEQQKTTEREKVVQE-KAQLQEQLRALEESLKIT 616
Cdd:pfam01576  461 KDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDernslqeQLEEEEEAKRNVERQLSTlQAQLSDMKKKLEEDAGTL 540

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1907176327  617 KGsLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELE 660
Cdd:pfam01576  541 EA-LEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELD 583
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
441-683 1.51e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.48  E-value: 1.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  441 MQEQEQAAQGLRQQVEQLssslklkEQQLEEAAKEQEATRQDHAqqlaIVAEAREASLRErdtarqqletvekekdAKLE 520
Cdd:COG3206    170 REEARKALEFLEEQLPEL-------RKELEEAEAALEEFRQKNG----LVDLSEEAKLLL----------------QQLS 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  521 SLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhacieASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQeka 600
Cdd:COG3206    223 ELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL-----LQSPVIQQLRAQLAELEAELAELSARYTPNHPDVI--- 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  601 QLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLME---QREREQKELEQE-KAGRKGLEARIQQL 676
Cdd:COG3206    295 ALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAelpELEAELRRLEREvEVARELYESLLQRL 374


                   ....*..
gi 1907176327  677 EEAHQAE 683
Cdd:COG3206    375 EEARLAE 381
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1151-1592 1.69e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.23  E-value: 1.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1151 ESKELKRLVVAESEKSQKLEERLRLLQvETASNSARAAERSSALREEVQSLREEVEKQRVVSENS--RQELASQAERAEE 1228
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQLLPLYQELEalEAELAELPERLEE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1229 LGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQR 1308
Cdd:COG4717    151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1309 ELGELGSLRQKIVEQERAaQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVR 1388
Cdd:COG4717    228 ELEQLENELEAAALEERL-KEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1389 TDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEER-QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQ 1467
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRiEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEE 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1468 AskvqqqklkafqAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAkthydakkQQNQKLQEQLQDLEELQK 1547
Cdd:COG4717    387 L------------RAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE--------ELEEELEELEEELEELEE 446

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1907176327 1548 ENKELRSEAERLGRELQQAGLKTK--EAEQTCRHLTAQVRSLEAQVA 1592
Cdd:COG4717    447 ELEELREELAELEAELEQLEEDGElaELLQELEELKAELRELAEEWA 493
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
528-1077 1.90e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 1.90e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  528 AANDARDNAQTSVTQAQQEKAELSQKigELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLR 607
Cdd:PRK02224   177 GVERVLSDQRGSLDQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  608 ALEES---LKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEE------ 678
Cdd:PRK02224   255 TLEAEiedLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDrleecr 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  679 ----AHQAETEALRH---------------------ELAEATASQHRAESECERLIREVESRQKRFE---ARQQEEARYG 730
Cdd:PRK02224   335 vaaqAHNEEAESLREdaddleeraeelreeaaelesELEEAREAVEDRREEIEELEEEIEELRERFGdapVDLGNAEDFL 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  731 AMFQEQLMALKGE--------KTGQEVQEEAVEIHSEGQ-PGQQQSQLAQLHASlakaiqQVQEKEVRAQKLVDDLSALQ 801
Cdd:PRK02224   415 EELREERDELREReaeleatlRTARERVEEAEALLEAGKcPECGQPVEGSPHVE------TIEEDRERVEELEAELEDLE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  802 EKMAATNKEVACLKTLVlkageqqetaslELLKEPPRAANRASD--QLGEQQgrpfsstHAAVKAMEREAEQMGGELERL 879
Cdd:PRK02224   489 EEVEEVEERLERAEDLV------------EAEDRIERLEERREDleELIAER-------RETIEEKRERAEELRERAAEL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  880 RAAliksqgqqqeergqqerevARLTQERGQAQADLAQEKAAK-AELEMRLQnTLNEQRVEFAALQEALAhALTEKEGTD 958
Cdd:PRK02224   550 EAE-------------------AEEKREAAAEAEEEAEEAREEvAELNSKLA-ELKERIESLERIRTLLA-AIADAEDEI 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  959 QELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQ 1038
Cdd:PRK02224   609 ERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVEN 688

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1907176327 1039 QCQQQQqqveglthSLKSERACRAEQDKALETLQGQLEE 1077
Cdd:PRK02224   689 ELEELE--------ELRERREALENRVEALEALYDEAEE 719
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
901-1445 1.93e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 1.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  901 VARLTQERGQAQADLAQEKAAKAELEmrLQNTLNEQRVEFAALQEALAHALTEKE---GTDQELAKLRGQEAAQRTELKE 977
Cdd:PRK02224   178 VERVLSDQRGSLDQLKAQIEEKEEKD--LHERLNGLESELAELDEEIERYEEQREqarETRDEADEVLEEHEERREELET 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  978 LQQTLEQL--KIQLVKKEKEHPAGGASGEDASGPGTQSE---TAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGL-- 1050
Cdd:PRK02224   256 LEAEIEDLreTIAETEREREELAEEVRDLRERLEELEEErddLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECrv 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1051 ---THSLKSERAcrAEQDKALETLQGQLEEKARELGhnqAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERK 1127
Cdd:PRK02224   336 aaqAHNEEAESL--REDADDLEERAEELREEAAELE---SELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNA 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1128 SSLISSLEEEVSILNRQVLEKEGESKELKRLVvaesEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEK 1207
Cdd:PRK02224   411 EDFLEELREERDELREREAELEATLRTARERV----EEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELED 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1208 QRVvsenSRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcqqlqaeqaAAEKRFRE 1287
Cdd:PRK02224   487 LEE----EVEEVEERLERAEDL-VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELR----------ERAAELEA 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1288 ELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLR---AEKASYAEQLSMLKKAHGLLAEENR----GLGE 1360
Cdd:PRK02224   552 EAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRtllAAIADAEDEIERLREKREALAELNDerreRLAE 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1361 RANLGRQfLEVELDQARekyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKvLEERQRFQEERQKLTAQ 1440
Cdd:PRK02224   632 KRERKRE-LEAEFDEAR---IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENE-LEELEELRERREALENR 706


                   ....*
gi 1907176327 1441 VEQLE 1445
Cdd:PRK02224   707 VEALE 711
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1360-1566 1.93e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.10  E-value: 1.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1360 ERANLGRQFLEVELDQAREKYVQ-ELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLT 1438
Cdd:COG3206    171 EEARKALEFLEEQLPELRKELEEaEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLG 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1439 AQVEQLEVFQreQTKQVEELSKKLTEhdqaskvQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAehyklqM 1518
Cdd:COG3206    251 SGPDALPELL--QSPVIQQLRAQLAE-------LEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRI------L 315

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1907176327 1519 EKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQA 1566
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVA 363
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1063-1563 2.06e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.85  E-value: 2.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1063 EQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAErksslISSLEEEVSILN 1142
Cdd:COG4717     78 EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAE-----LAELPERLEELE 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1143 RQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQ 1222
Cdd:COG4717    153 ERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1223 AERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAkhlcqqlqaeqaaaekrfreeleqskQAAGGLQAE 1302
Cdd:COG4717    233 ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAG--------------------------VLFLVLGLL 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1303 LMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQ 1382
Cdd:COG4717    287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1383 ELaavrtdaETHLAEMRQEAQSTSRElevmtakyegakvkVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKL 1462
Cdd:COG4717    367 EL-------EQEIAALLAEAGVEDEE--------------ELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1463 TEHDQASKVQQ--QKLKAFQAQRGESQQEVQRLQTQLNEL--QAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQ 1538
Cdd:COG4717    426 DEEELEEELEEleEELEELEEELEELREELAELEAELEQLeeDGELAELLQELEELKAELRELAEEWAALKLALELLEEA 505

                          490       500
                   ....*....|....*....|....*
gi 1907176327 1539 LQDLEELQKEnkELRSEAERLGREL 1563
Cdd:COG4717    506 REEYREERLP--PVLERASEYFSRL 528
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
360-557 2.07e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 2.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  360 RSRFEDEKQQLASLiADLQSSVSNLSQAKEELEQASQ-AQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQML 438
Cdd:COG4913    241 HEALEDAREQIELL-EPIRELAERYAAARERLAELEYlRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLD 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  439 QTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLetvekekDAK 518
Cdd:COG4913    320 ALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA-------AAL 392

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1907176327  519 LESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGEL 557
Cdd:COG4913    393 LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASL 431
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
492-785 2.12e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 2.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  492 EAREASLRE------RDTARQQLETVEKEKDAKLESLQQQLQAAndarDNAQTSVTQAQQEKAELSQKIGELHACIEASH 565
Cdd:PRK03918   145 ESREKVVRQilglddYENAYKNLGEVIKEIKRRIERLEKFIKRT----ENIEELIKEKEKELEEVLREINEISSELPELR 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  566 QEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLE--EEKRRAADALKEQQCRATEMEA 643
Cdd:PRK03918   221 EELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEelEEKVKELKELKEKAEEYIKLSE 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  644 ESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAhQAETEALRHELAE------ATASQHRAESECERLIREVESRQK 717
Cdd:PRK03918   301 FYEEYLDELREIEKRLSRLEEEINGIEERIKELEEK-EERLEELKKKLKElekrleELEERHELYEEAKAKKEELERLKK 379

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327  718 RFEARQQEEArygamfQEQLMALKGEKTgqEVQEEAVEIhsegqpGQQQSQLAQLHASLAKAIQQVQE 785
Cdd:PRK03918   380 RLTGLTPEKL------EKELEELEKAKE--EIEEEISKI------TARIGELKKEIKELKKAIEELKK 433
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 352-814 2.28e-06

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 52.88  E-value: 2.28e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  352 QEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQltsmtglnATLQQRDQELASLKEQAK 431
Cdd:PRK10246   217 QVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDELQQEASRRQQALQQAL--------AAEEKAQPQLAALSLAQP 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  432 KEQAQML-QTMQEQEQAAQGLRQQVEQLSSSLKLKEQQ---LEEAAKEQEATRQDHAQQLAI-VAEAREASLRERDTA-- 504
Cdd:PRK10246   289 ARQLRPHwERIQEQSAALAHTRQQIEEVNTRLQSTMALrarIRHHAAKQSAELQAQQQSLNTwLAEHDRFRQWNNELAgw 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  505 RQQLETVEKEKdAKLESLQQQLQAANDARDNAQTS--------VTQA---QQEKAELSQKIGELHACIEASHQEQRQVQA 573
Cdd:PRK10246   369 RAQFSQQTSDR-EQLRQWQQQLTHAEQKLNALPAItltltadeVAAAlaqHAEQRPLRQRLVALHGQIVPQQKRLAQLQV 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  574 RVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKgSLEEEKRRAADALKEQQCRATEMEAESrslmeqrE 653
Cdd:PRK10246   448 AIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIK-DLEAQRAQLQAGQPCPLCGSTSHPAVE-------A 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  654 REQKELEQEKAGRKGLEARIQQLEEahqaETEALRHELAEATASQHRAESECERLIREvesRQKRFEARQQEEARYGAMF 733
Cdd:PRK10246   520 YQALEPGVNQSRLDALEKEVKKLGE----EGAALRGQLDALTKQLQRDESEAQSLRQE---EQALTQQWQAVCASLNITL 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  734 QEQlMALKGEKTGQEVQEEAVEihsegQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVAC 813
Cdd:PRK10246   593 QPQ-DDIQPWLDAQEEHERQLR-----LLSQRHELQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEASW 666


                   .
gi 1907176327  814 L 814
Cdd:PRK10246   667 L 667
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
161-557 2.30e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.85  E-value: 2.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  161 QQRIDHLALLNEKQAASSQEPSELEELRGKNESLtVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHL 240
Cdd:COG4717     91 AELQEELEELEEELEELEAELEELREELEKLEKL-LQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELE 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  241 QQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQ-ESPAPEKGEVLGDAL 319
Cdd:COG4717    170 AELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEnELEAAALEERLKEAR 249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  320 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 399
Cdd:COG4717    250 LLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALG 329

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  400 AQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLrQQVEQLSSSLKLKEQQLEEAAKEQEAT 479
Cdd:COG4717    330 LPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGV-EDEEELRAALEQAEEYQELKEELEELE 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  480 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTS--VTQAQQEKAELSQKIGEL 557
Cdd:COG4717    409 EQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDgeLAELLQELEELKAELREL 488
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 126-995 2.61e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.67  E-value: 2.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  126 KKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQC 205
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  206 QNLKTEKSQ--------MDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQ 277
Cdd:pfam02463  260 IEKEEEKLAqvlkenkeEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  278 DKKCLEEKnEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQtrvetlecERGKQEAQLL 357
Cdd:pfam02463  340 LEKELKEL-EIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELK--------SEEEKEAQLL 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  358 AERSrfedekQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQM 437
Cdd:pfam02463  411 LELA------RQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  438 LQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDA 517
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  518 KLeslqqqLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQ 597
Cdd:pfam02463  565 KL------VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  598 EKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLE 677
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLE 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  678 EahqAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEaveih 757
Cdd:pfam02463  719 A---EELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEE----- 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  758 segqpgQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEpp 837
Cdd:pfam02463  791 ------EKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE-- 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  838 raaNRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQ 917
Cdd:pfam02463  863 ---ITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327  918 EKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKE 995
Cdd:pfam02463  940 LLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 202-790 3.06e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 52.74  E-value: 3.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  202 LKQCQNLKTEKSQMDRKISQLSEENGDLsfkvrefaNHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQD--- 278
Cdd:TIGR00606  500 KKEVKSLQNEKADLDRKLRKLDQEMEQL--------NHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfpn 571

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  279 KKCLEEKNEILQGKLSQLEDQATRLQESPAPekgevlGDALQLDTLKQEAAKLATDNTQLQTRVETLECErgKQEAQLLA 358
Cdd:TIGR00606  572 KKQLEDWLHSKSKEINQTRDRLAKLNKELAS------LEQNKNHINNELESKEEQLSSYEDKLFDVCGSQ--DEESDLER 643

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  359 ERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQA---------SQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQ 429
Cdd:TIGR00606  644 LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCcpvcqrvfqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK 723

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  430 AKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAtrqdhaQQLAIVAEAREASLRERD-TARQQL 508
Cdd:TIGR00606  724 RRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQET------LLGTIMPEEESAKVCLTDvTIMERF 797

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  509 ETVEKEKDAKLESLQQQLQAANDARdnAQTSVTQAQQEKAE----LSQKIGELHACIEASHQEQRQVQARVTELEAQLKA 584
Cdd:TIGR00606  798 QMELKDVERKIAQQAAKLQGSDLDR--TVQQVNQEKQEKQHeldtVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQ 875

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  585 EQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKA 664
Cdd:TIGR00606  876 IGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHG 955

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  665 GRKGLEARIQQLEEAHQAETEalrHELAEATASQHRAESECERLIREVESRQKRFEARQQEEarygAMFQEQLMALKGEK 744
Cdd:TIGR00606  956 YMKDIENKIQDGKDDYLKQKE---TELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQE----RWLQDNLTLRKREN 1028

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1907176327  745 TGQEVQEEAVEihSEGQPGQQQ-SQLAQLHASLAKAIQQVQEKEVRA 790
Cdd:TIGR00606 1029 ELKEVEEELKQ--HLKEMGQMQvLQMKQEHQKLEENIDLIKRNHVLA 1073
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1189-1591 3.80e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 3.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1189 ERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELkawqekffqkEQALSALQLEHTSTQALvsellpak 1268
Cdd:PRK02224   251 EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER----------DDLLAEAGLDDADAEAV-------- 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1269 hlcQQLQAEQAAAEKRFREELEQSKQAAGGLQAElmrAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAH 1348
Cdd:PRK02224   313 ---EARREELEDRDEELRDRLEECRVAAQAHNEE---AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEI 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1349 GLLAEENRGLGERANlgrqFLEVELDQArEKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAK-------- 1420
Cdd:PRK02224   387 EELEEEIEELRERFG----DAPVDLGNA-EDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpv 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1421 -----VKVLEERQrfqEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQ-----KLKAFQAQRGESQQE- 1489
Cdd:PRK02224   462 egsphVETIEEDR---ERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERredleELIAERRETIEEKREr 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1490 VQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTH---YDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQA 1566
Cdd:PRK02224   539 AEELRERAAELEAEAEEKREAAAEAEEEAEEAREEvaeLNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREAL 618

                          410       420
                   ....*....|....*....|....*
gi 1907176327 1567 GLKTKEAEQTCRHLTAQVRSLEAQV 1591
Cdd:PRK02224   619 AELNDERRERLAEKRERKRELEAEF 643
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1119-1567 3.93e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 52.26  E-value: 3.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1119 RGQQEAERKSSLISSLEEEVSILNRQVLEKEGE----SKELKRLVVAESEKSQKLE---ERLRLLQvetasNSARAAERS 1191
Cdd:COG3096    275 RHANERRELSERALELRRELFGARRQLAEEQYRlvemARELEELSARESDLEQDYQaasDHLNLVQ-----TALRQQEKI 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1192 SALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLC 1271
Cdd:COG3096    350 ERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARALC 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1272 qqlqaeqaaaekrfrEELEQSKQAAGGLQAELMRAQRELGE-LGSLRQKIVEQERAAQQlraekasYAEQLSMLKKAHGl 1350
Cdd:COG3096    430 ---------------GLPDLTPENAEDYLAAFRAKEQQATEeVLELEQKLSVADAARRQ-------FEKAYELVCKIAG- 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1351 laeenrglgeranlgrqflEVELDQAREKYVQELAAVRTDAetHLAEMRQEAQSTSRELEvmtakyegakvkvleerQRF 1430
Cdd:COG3096    487 -------------------EVERSQAWQTARELLRRYRSQQ--ALAQRLQQLRAQLAELE-----------------QRL 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1431 qEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQA 1510
Cdd:COG3096    529 -RQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAA 607

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176327 1511 AEHY-KLQMEKAKTHYDAKKQQNQkLQEQLQDLEELQKENKELRSEAERLG---RELQQAG 1567
Cdd:COG3096    608 QDALeRLREQSGEALADSQEVTAA-MQQLLEREREATVERDELAARKQALEsqiERLSQPG 667
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1025-1559 4.42e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.96  E-value: 4.42e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1025 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEqdkaLETLQGQLEEKarelghnQAASASAQRELQALRAKAQ 1104
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE----LETLEAEIEDL-------RETIAETEREREELAEEVR 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1105 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQvlekegeskelkrlvvaESEKSQKLEERlRLLQVETASNS 1184
Cdd:PRK02224   283 DLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDR-----------------DEELRDRLEEC-RVAAQAHNEEA 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1185 ARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1264
Cdd:PRK02224   345 ESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDEL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1265 LPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGElgsLRQKIVEQERAAQQLRAEKASYAEQLSML 1344
Cdd:PRK02224   425 REREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEE---DRERVEELEAELEDLEEEVEEVEERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1345 KKAHGLLAEENRgLGERanlgRQFLEVELDQAREKyvqelAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVL 1424
Cdd:PRK02224   502 EDLVEAEDRIER-LEER----REDLEELIAERRET-----IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1425 EERQRFQEERQKLTAQVEQLEvfqreqtkQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQA-- 1502
Cdd:PRK02224   572 EEVAELNSKLAELKERIESLE--------RIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAef 643

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176327 1503 ------QLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQK----LQEQLQDLEELQKENKELRSEAERL 1559
Cdd:PRK02224   644 dearieEAREDKERAEEYLEQVEEKLDELREERDDLQAeigaVENELEELEELRERREALENRVEAL 710
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 114-685 7.08e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.51  E-value: 7.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  114 ILQTPQFQMRRLKKQLADERSNRDDLELELSESLKLLTekdaqiamMQQRIDHLALLNEKQAA----SSQEPSELEELRG 189
Cdd:TIGR00618  312 IHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT--------LHSQEIHIRDAHEVATSireiSCQQHTLTQHIHT 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  190 KNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVRefANHLQQLQGAFNDLIEEHSKASQEWAEKQARLE 269
Cdd:TIGR00618  384 LQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAH--AKKQQELQQRYAELCAAAITCTAQCEKLEKIHL 461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  270 NELSTALQDKKCLEEKNEILQGKLSQL----EDQATRLQESPAPEKGEVLGDALQLdTLKQEAAKLATDNTQLQTRVETL 345
Cdd:TIGR00618  462 QESAQSLKEREQQLQTKEQIHLQETRKkavvLARLLELQEEPCPLCGSCIHPNPAR-QDIDNPGPLTRRMQRGEQTYAQL 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  346 ECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASqaqgaQLTAQLTSMTGLNATLQQRDQELAS 425
Cdd:TIGR00618  541 ETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQ-----NITVRLQDLTEKLSEAEDMLACEQH 615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  426 LKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSS-SLKLKEQQLEEAAKeqeATRQDHAQQLAIvaeaREASLRERDTA 504
Cdd:TIGR00618  616 ALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHAlQLTLTQERVREHAL---SIRVLPKELLAS----RQLALQKMQSE 688

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  505 RQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACI-EASHQEQRQVQARVTELE---A 580
Cdd:TIGR00618  689 KEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLkELMHQARTVLKARTEAHFnnnE 768

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  581 QLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELE 660
Cdd:TIGR00618  769 EVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEIT 848

                          570       580
                   ....*....|....*....|....*
gi 1907176327  661 QEKagrKGLEARIQQLEEAHQAETE 685
Cdd:TIGR00618  849 HQL---LKYEECSKQLAQLTQEQAK 870
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1434-1601 8.40e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 8.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1434 RQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEH 1513
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1514 YKL--QMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTK-EAEQTCRHLTAQVRSLEAQ 1590
Cdd:COG4717    128 LPLyqELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQR 207

                          170
                   ....*....|.
gi 1907176327 1591 VAHADQQLRDL 1601
Cdd:COG4717    208 LAELEEELEEA 218
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1048-1580 1.28e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 50.35  E-value: 1.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1048 EGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARgQQEAERK 1127
Cdd:TIGR00618  197 ELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRAR-IEELRAQ 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1128 SSLISSLEEEVSiLNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEK 1207
Cdd:TIGR00618  276 EAVLEETQERIN-RARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1208 QRVVSENSRQEL-ASQAERAEELGQELKAWQEK---FFQKEQALSALQLEHTSTQALVSEL----------LPAKHLCQQ 1273
Cdd:TIGR00618  355 IHIRDAHEVATSiREISCQQHTLTQHIHTLQQQkttLTQKLQSLCKELDILQREQATIDTRtsafrdlqgqLAHAKKQQE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1274 LQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKAS-YAEQLSMLKKAHGLLA 1352
Cdd:TIGR00618  435 LQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLeLQEEPCPLCGSCIHPN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1353 EENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAET-HLAEMRQEAQSTSRELEVMTAKYEGAKV---KVLEERQ 1428
Cdd:TIGR00618  515 PARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERkQRASLKEQMQEIQQSFSILTQCDNRSKEdipNLQNITV 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1429 RFQEERQKLTAQVEQLEVFQREQTKQVEE---LSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLS 1505
Cdd:TIGR00618  595 RLQDLTEKLSEAEDMLACEQHALLRKLQPeqdLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKEL 674

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176327 1506 QKEQAAEHYKLQMEKAKTHYDAK--KQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHL 1580
Cdd:TIGR00618  675 LASRQLALQKMQSEKEQLTYWKEmlAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQ 751
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 411-527 1.33e-05

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 48.35  E-value: 1.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  411 GLNATLQQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGlRQQVEQLSSSLKLKEQQLEEAAKEQEaTRQDHAQQLAIV 490
Cdd:NF038305    98 HLNNTRRLSTQALQQINQQAGQQETQ-LQQQLNQLQAQTS-PQQLNQLLKSEQKQGQALASGQLPEE-QKEQLQQFKSNP 174

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1907176327  491 AEAREASLRERDTARQQLETVEKEkdAKLESLQQQLQ 527
Cdd:NF038305   175 QALDKFLAQQLTQIRTQAEEAEKQ--ARLEALKSSLR 209
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 536-753 1.35e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  536 AQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREkvvQEKAQLQEQLRALEESLKI 615
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  616 TKGSLEEEKRRAADALKEQQ--------------CRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAhQ 681
Cdd:COG4942     95 LRAELEAQKEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE-R 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176327  682 AETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEA 753
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1097-1229 1.44e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 50.24  E-value: 1.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1097 QALRaKAQDHSKAEEEWKAQVARGQQEAERkssliSSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL 1176
Cdd:COG2433    380 EALE-ELIEKELPEEEPEAEREKEHEEREL-----TEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEA 453

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176327 1177 QVEtASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELasqaERAEEL 1229
Cdd:COG2433    454 RSE-ERREIRKDREISRLDREIERLERELEEERERIEELKRKL----ERLKEL 501
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1091-1619 1.68e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.22  E-value: 1.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1091 SAQRELQALRAKAQDHSKAEEEWKAQVARGQQEaerKSSLISSLEEEVsilNRQVLEKEGESKELKRLVVAESEKSQKLE 1170
Cdd:pfam12128  255 SAELRLSHLHFGYKSDETLIASRQEERQETSAE---LNQLLRTLDDQW---KEKRDELNGELSAADAAVAKDRSELEALE 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1171 ERLRLLQVETASNSARAAERSSALREEVQSLREEVE-----KQRVVSENSRQELASQAERAEELgQELKAWQEKffQKEQ 1245
Cdd:pfam12128  329 DQHGAFLDADIETAAADQEQLPSWQSELENLEERLKaltgkHQDVTAKYNRRRSKIKEQNNRDI-AGIKDKLAK--IREA 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1246 ALSALQLEHTSTQALVSELlpakhlcqqlQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQER 1325
Cdd:pfam12128  406 RDRQLAVAEDDLQALESEL----------REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1326 AAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGeRANLGRQFLEVELDQAREKYVQE----LAAVRTDA---ETHLAEM 1398
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALR-QASRRLEERQSALDELELQLFPQagtlLHFLRKEApdwEQSIGKV 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1399 RQEAQ-------------STSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEH 1465
Cdd:pfam12128  555 ISPELlhrtdldpevwdgSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGEL 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1466 DQASKVQQQKLKAFQAQRgesqqevQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAkkQQNQKLQEQLQDLEEL 1545
Cdd:pfam12128  635 EKASREETFARTALKNAR-------LDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEA--QLKQLDKKHQAWLEEQ 705

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327 1546 QKENKELRSEAERLGRELQQAgLKTKEAEQTCRHLTAQVrSLEAQVAHADQQL-RDLGKFQVATDALKSREPQVK 1619
Cdd:pfam12128  706 KEQKREARTEKQAYWQVVEGA-LDAQLALLKAAIAARRS-GAKAELKALETWYkRDLASLGVDPDVIAKLKREIR 778
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1479-1601 1.77e-05

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 49.28  E-value: 1.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1479 FQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEhYKLQMEKAKTHYDAKKQQ---NQKLQEQ----LQDLEELQKENKE 1551
Cdd:COG1566     81 LQAALAQAEAQLAAAEAQLARLEAELGAEAEIAA-AEAQLAAAQAQLDLAQRElerYQALYKKgavsQQELDEARAALDA 159

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1552 LRSEAERLGRELQQAGLKTKEAEQTcRHLTAQVRSLEAQVAHADQQLRDL 1601
Cdd:COG1566    160 AQAQLEAAQAQLAQAQAGLREEEEL-AAAQAQVAQAEAALAQAELNLART 208
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 313-989 1.80e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.17  E-value: 1.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  313 EVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAE----------RSRFEDEKQQLASLIADLQSSVS 382
Cdd:pfam01576    6 EMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAEtelcaeaeemRARLAARKQELEEILHELESRLE 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  383 NLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLqTMQEQEQAAQGLRQQVEQLSSSL 462
Cdd:pfam01576   86 EEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDIL-LLEDQNSKLSKERKLLEERISEF 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  463 KLKEQQLEEAAKEQEATRQDHAQQLAIVaearEASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQ 542
Cdd:pfam01576  165 TSNLAEEEEKAKSLSKLKNKHEAMISDL----EERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAK 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  543 AQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQEQLRA----LEESLKITKG 618
Cdd:pfam01576  241 KEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERA---ARNKAEKQRRDLGEELEAlkteLEDTLDTTAA 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  619 SLEEEKRRAADALKEQQCRATEMEAESRSLMEQRERE-------QKELEQEKAGRKGLEARIQQLEEAhqaetealRHEL 691
Cdd:pfam01576  318 QQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHtqaleelTEQLEQAKRNKANLEKAKQALESE--------NAEL 389

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  692 AEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGE---KTGQEVQEEAVEIHSEGQPGQQQSQ 768
Cdd:pfam01576  390 QAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSElesVSSLLNEAEGKNIKLSKDVSSLESQ 469

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  769 LAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKM-------AATNKEVACLKTLV--LKAGEQQETASLELLKEPPRA 839
Cdd:pfam01576  470 LQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLeeeeeakRNVERQLSTLQAQLsdMKKKLEEDAGTLEALEEGKKR 549

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  840 ANRASDQLGEQqgrpFSSTHAAVKAMEREAEQMGGELE----------RLRAALIKSQGQQQEERGQQEREVARLTQERG 909
Cdd:pfam01576  550 LQRELEALTQQ----LEEKAAAYDKLEKTKNRLQQELDdllvdldhqrQLVSNLEKKQKKFDQMLAEEKAISARYAEERD 625

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  910 QAQADlAQEKAAKAELEMRLQNTLNEQRVEF----AALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQL 985
Cdd:pfam01576  626 RAEAE-AREKETRALSLARALEEALEAKEELertnKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEEL 704


                   ....
gi 1907176327  986 KIQL 989
Cdd:pfam01576  705 EDEL 708
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 429-722 1.88e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.95  E-value: 1.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  429 QAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEA----AKEQEATRQ----DHAQQ--------LAIVAE 492
Cdd:COG3096    289 ELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAAsdhlNLVQTALRQqekiERYQEdleelterLEEQEE 368

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  493 AREASLRERDTARQQLETVEKEKDakleSLQQQLQAANDARDNAQTSVTQAQQEKaelsQKIGELHACIEASHQEQRQVQ 572
Cdd:COG3096    369 VVEEAAEQLAEAEARLEAAEEEVD----SLKSQLADYQQALDVQQTRAIQYQQAV----QALEKARALCGLPDLTPENAE 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  573 ARVTELEAQlkaEQQKTTEREKVVQEKAQLQEQLRALEESLK-ITKGSLEEEKRRAADALKEQQCRATEMEAESRSL--- 648
Cdd:COG3096    441 DYLAAFRAK---EQQATEEVLELEQKLSVADAARRQFEKAYElVCKIAGEVERSQAWQTARELLRRYRSQQALAQRLqql 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  649 ------MEQREREQ-------KELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQhraeSECERLIREVESR 715
Cdd:COG3096    518 raqlaeLEQRLRQQqnaerllEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQR----SELRQQLEQLRAR 593


                   ....*..
gi 1907176327  716 QKRFEAR 722
Cdd:COG3096    594 IKELAAR 600
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
412-806 1.97e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.77  E-value: 1.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  412 LNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHaQQLAIVA 491
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREEL-EKLEKLL 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  492 EAREAsLRERDTARQQLETVE------KEKDAKLESLQQQLQAANDARDNAQTSVTQA-QQEKAELSQKIGELHACIEAS 564
Cdd:COG4717    126 QLLPL-YQELEALEAELAELPerleelEERLEELRELEEELEELEAELAELQEELEELlEQLSLATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  565 HQEQRQVQARVTELEAQLKAEQQKTTEREKvVQEKAQLQEQLRALEESLKI---------TKGSLEEEKRRAADALKEQQ 635
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLEN-ELEAAALEERLKEARLLLLIaaallallgLGGSLLSLILTIAGVLFLVL 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  636 CRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAE------------ATASQHRAES 703
Cdd:COG4717    284 GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLElldrieelqellREAEELEEEL 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  704 ECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKtgQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQV 783
Cdd:COG4717    364 QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEEL--EELEEQLEELLGELEELLEALDEEELEEELEELEEEL 441

                          410       420
                   ....*....|....*....|...
gi 1907176327  784 QEKEVRAQKLVDDLSALQEKMAA 806
Cdd:COG4717    442 EELEEELEELREELAELEAELEQ 464
PRK12704 PRK12704
phosphodiesterase; Provisional
 466-664 2.71e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 49.01  E-value: 2.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  466 EQQLEEAAKEQEATRQDhaqqlaIVAEAREaslrERDTARQQLETVEKEKDAKLESLQQQLqaandardnaqtsvtqaQQ 545
Cdd:PRK12704    41 KRILEEAKKEAEAIKKE------ALLEAKE----EIHKLRNEFEKELRERRNELQKLEKRL-----------------LQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  546 EKAELSQKIGELhacieashqEQRqvQARVTELEAQLKAEQQKTTEREKVVQEKaqLQEQLRALEESLKITKgslEEEKR 625
Cdd:PRK12704    94 KEENLDRKLELL---------EKR--EEELEKKEKELEQKQQELEKKEEELEEL--IEEQLQELERISGLTA---EEAKE 157

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1907176327  626 RAADALKEqqcratEMEAESRSLMEQREREQKELEQEKA 664
Cdd:PRK12704   158 ILLEKVEE------EARHEAAVLIKEIEEEAKEEADKKA 190
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
916-1445 2.98e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 2.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  916 AQEKAAKAELEMRLQNTLnEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLvkkeke 995
Cdd:COG4913    260 LAERYAAARERLAELEYL-RAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQI------ 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  996 hpaggasgedasgpgtqsetagkTDAPGPELQALRAEISKLEQQCQQQQQQveglthslkseracRAEQDKALETLQGQL 1075
Cdd:COG4913    333 -----------------------RGNGGDRLEQLEREIERLERELEERERR--------------RARLEALLAALGLPL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1076 EEKARELGHNQAASASAQRELQALRAKAQDhskAEEEWKAQVARGQQEAERKSSLISSLEEEVS------ILNRQVLEKE 1149
Cdd:COG4913    376 PASAEEFAALRAEAAALLEALEEELEALEE---ALAEAEAALRDLRRELRELEAEIASLERRKSniparlLALRDALAEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1150 -----------GESKELK-------------------RLVVAESEKSQ--------KLEERLRLLQVETASNSARAAE-- 1189
Cdd:COG4913    453 lgldeaelpfvGELIEVRpeeerwrgaiervlggfalTLLVPPEHYAAalrwvnrlHLRGRLVYERVRTGLPDPERPRld 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1190 ----------RSSALREEVQSL----------------------------------------REEVEKQRVVSENSRQEL 1219
Cdd:COG4913    533 pdslagkldfKPHPFRAWLEAElgrrfdyvcvdspeelrrhpraitragqvkgngtrhekddRRRIRSRYVLGFDNRAKL 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1220 ASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALvsellpakhlcqqlqaeqaaaekrfrEELEQSKQAAGGL 1299
Cdd:COG4913    613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRL--------------------------AEYSWDEIDVASA 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1300 QAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEnrglgeranlgRQFLEVELDQAREK 1379
Cdd:COG4913    667 EREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKE-----------LEQAEEELDELQDR 735

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176327 1380 YVQELAAVRTDAETHLAEMRQEAQSTSRELEVmtakyegakvkvleeRQRFQEERQKLTAQVEQLE 1445
Cdd:COG4913    736 LEAAEDLARLELRALLEERFAAALGDAVEREL---------------RENLEERIDALRARLNRAE 786
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 764-995 3.05e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  764 QQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEvaclktlvLKAGEQQETASLELLKEPPRAANRA 843
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR--------IRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  844 SDQLGEQQgrpfssthAAVKAMEREAEQMGgeleRLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKA 923
Cdd:COG4942     96 RAELEAQK--------EELAELLRALYRLG----RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176327  924 ELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKE 995
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1374-1646 3.07e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.27  E-value: 3.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1374 DQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKvKVLEERQRFQEERQKLTAQVEQLEVFQREQTK 1453
Cdd:PRK02224   194 AQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEAD-EVLEEHEERREELETLEAEIEDLRETIAETER 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1454 QVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAaehyklqMEKAKTHYDAKKQQNQ 1533
Cdd:PRK02224   273 EREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDR-------LEECRVAAQAHNEEAE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1534 KLQEQLQDLEElqkENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKS 1613
Cdd:PRK02224   346 SLREDADDLEE---RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERD 422

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1907176327 1614 REPQVKPQLDLSIDSLDLSLEEGTPCSVASKLP 1646
Cdd:PRK02224   423 ELREREAELEATLRTARERVEEAEALLEAGKCP 455
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1186-1602 3.07e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.29  E-value: 3.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1186 RAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELL 1265
Cdd:PRK03918   162 NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1266 PAKhlcqQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERaaqqLRAEKASYAEQLSMLK 1345
Cdd:PRK03918   242 ELE----KELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK----LSEFYEEYLDELREIE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1346 KAHGLLAEENRGLGERANLGRQFLEV--ELDQAREKYVQELAAVRTDAETH------LAEMRQ-EAQSTSRELEVMTAKY 1416
Cdd:PRK03918   314 KRLSRLEEEINGIEERIKELEEKEERleELKKKLKELEKRLEELEERHELYeeakakKEELERlKKRLTGLTPEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1417 EGAKvkvlEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSK----------KLTEHDQASKVQQ--QKLKAFQAQRG 1484
Cdd:PRK03918   394 EELE----KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrELTEEHRKELLEEytAELKRIEKELK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1485 ESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQ 1564
Cdd:PRK03918   470 EIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELE 549

                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 1907176327 1565 qaglKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLG 1602
Cdd:PRK03918   550 ----KLEELKKKLAELEKKLDELEEELAELLKELEELG 583
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1066-1257 3.16e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 3.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1066 KALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQ--VARGQQEAERKSSLISSLEE---EVSI 1140
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidVASAEREIAELEAELERLDAssdDLAA 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1141 LNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEvqsLREEVEKQRvvsensRQELA 1220
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLE---LRALLEERF------AAALG 760

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1907176327 1221 SQAER--AEELGQELKAWQEKFFQKEQALSALQLEHTST 1257
Cdd:COG4913    761 DAVERelRENLEERIDALRARLNRAEEELERAMRAFNRE 799
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1025-1575 3.63e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.20  E-value: 3.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1025 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1104
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1105 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERL---RLLQVETA 1181
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKeeeLELKSEEE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1182 SNSARAAERSSALREEVQSLREEVEKQRVVSENSRQ-ELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQAL 1260
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIElKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1261 VSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGEL--GSLRQKIVEQERAAQQLRAEKASYA 1338
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAveNYKVAISTAVIVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1339 EQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQE-AQSTSRELEVMTAKYE 1417
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGiLKDTELTKLKESAKAK 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1418 GAKVKVLEERQRFQEERQKLTAQVEQLevfQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQL 1497
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEKSEVKASLSEL---TKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327 1498 NELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQ 1575
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQ 799
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
44-625 4.09e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.88  E-value: 4.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327   44 DHEESLNLTEDLESFLEKVPYTHASTLSE--ELSPPSHQTKRKIRFLEiQRIASSSSENNFLSGSPSSpmgdilqtpqfq 121
Cdd:PRK02224   245 EHEERREELETLEAEIEDLRETIAETEREreELAEEVRDLRERLEELE-EERDDLLAEAGLDDADAEA------------ 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  122 mrrLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLAllnekqaassqepSELEELRGKNESLTVRLHET 201
Cdd:PRK02224   312 ---VEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE-------------ERAEELREEAAELESELEEA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  202 LKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEhskasqewaekqarlENELSTALQDKKC 281
Cdd:PRK02224   376 REAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRER---------------EAELEATLRTARE 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  282 LEEKNEILqgklsqledqatrLQESPAPEKGEVLGDALQLDTL---KQEAAKLATDNTQLQTRVETLE--CERGKQEAQL 356
Cdd:PRK02224   441 RVEEAEAL-------------LEAGKCPECGQPVEGSPHVETIeedRERVEELEAELEDLEEEVEEVEerLERAEDLVEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  357 LAERSRFEDEKQQLASLIADLQssvsnlsqakeeleqasqaqgaqltaqltsmtglnATLQQRDQELASLKEQAKKEQAQ 436
Cdd:PRK02224   508 EDRIERLEERREDLEELIAERR-----------------------------------ETIEEKRERAEELRERAAELEAE 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  437 mlqtMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRqDHAQQLAIVAEAREA--SLRERDTARQQLETVEKE 514
Cdd:PRK02224   553 ----AEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEieRLREKREALAELNDERRE 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  515 KDAKLESLQQQLQAANDArdnaqTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKaEQQKTTEREK 594
Cdd:PRK02224   628 RLAEKRERKRELEAEFDE-----ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELE-ELEELRERRE 701

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1907176327  595 VVQEKAQLQEQLRALEESLKITKGSLEEEKR 625
Cdd:PRK02224   702 ALENRVEALEALYDEAEELESMYGDLRAELR 732
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 320-724 4.17e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 49.03  E-value: 4.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  320 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASL---------IADLQSSVSNLSQAKEE 390
Cdd:PRK10246   427 RLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVkticeqearIKDLEAQRAQLQAGQPC 506

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  391 LEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQ---MLQTMQEQEQAAQGLRQQVEQLSS------- 460
Cdd:PRK10246   507 PLCGSTSHPAVEAYQALEPGVNQSRLDALEKEVKKLGEEGAALRGQldaLTKQLQRDESEAQSLRQEEQALTQqwqavca 586

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  461 SLKLKEQQLEEAAKEQEAtRQDHAQQLAIVAEARE------ASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND--- 531
Cdd:PRK10246   587 SLNITLQPQDDIQPWLDA-QEEHERQLRLLSQRHElqgqiaAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEeas 665

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  532 ---ARDNAQTSVTQAQQEKAELSQKIGELHACIE--------------ASHQEQRQVQARVTELEAQLKAEQQKTTerek 594
Cdd:PRK10246   666 wlaTRQQEAQSWQQRQNELTALQNRIQQLTPLLEtlpqsddlphseetVALDNWRQVHEQCLSLHSQLQTLQQQDV---- 741

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  595 vvQEKAQLQEQLRALEESLkitKGSLEEEKRRAADALkeqqcrateMEAESRSLMEQRereQKELEQEKAGRKGLEARIQ 674
Cdd:PRK10246   742 --LEAQRLQKAQAQFDTAL---QASVFDDQQAFLAAL---------LDEETLTQLEQL---KQNLENQRQQAQTLVTQTA 804

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176327  675 QLEEAHQAETEALRHELAEATASQHRAESECERLiREVESRQKrfEARQQ 724
Cdd:PRK10246   805 QALAQHQQHRPDGLDLTVTVEQIQQELAQLAQQL-RENTTRQG--EIRQQ 851
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 485-862 4.29e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.06  E-value: 4.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  485 QQLAIVAEAREASLRERDTARQQ-LETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGElhaciea 563
Cdd:NF012221  1503 KTLKLTAKAGSNRLEFKGTGHNDgLGYILDNVVATSESSQQADAVSKHAKQDDAAQNALADKERAEADRQRLE------- 1575

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  564 shQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGsleeekrraADALKEQQCRATEMEA 643
Cdd:NF012221  1576 --QEKQQQLAAISGSQSQLESTDQNALETNGQAQRDAILEESRAVTKELTTLAQG---------LDALDSQATYAGESGD 1644

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  644 ESRSLMEQR--EREQKELEQEKagrKGLEARIQQLEEAHQAETEALRHELAEATASQHRAesecERLIREVESRQKrfEA 721
Cdd:NF012221  1645 QWRNPFAGGllDRVQEQLDDAK---KISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQG----EQNQANAEQDID--DA 1715

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  722 RQQEEARYGAMFQEQLMALKGEKTGQEVQEEAveihseGQPGQQQSQLAQLHASLAKAiqqvqekevraqklvDDLSALQ 801
Cdd:NF012221  1716 KADAEKRKDDALAKQNEAQQAESDANAAANDA------QSRGEQDASAAENKANQAQA---------------DAKGAKQ 1774

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176327  802 EKMAATNKEVACLKTLVLKAGEQQETA--SLELLKEPPRAAN-RASDQLGEQQGRPFSSTHAAV 862
Cdd:NF012221  1775 DESDKPNRQGAAGSGLSGKAYSVEGVAepGSHINPDSPAAADgRFSEGLTEQEQEALEGATNAV 1838
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1286-1590 4.34e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.80  E-value: 4.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1286 REELEQSKQAAGGLQAELMRAQRELGELGSlRQKIVEQE-----------RAAQQLRAEKASYAEQLSMLKKAhgllAEE 1354
Cdd:COG3096    291 RRELFGARRQLAEEQYRLVEMARELEELSA-RESDLEQDyqaasdhlnlvQTALRQQEKIERYQEDLEELTER----LEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1355 NRGLGERANLGRQFLEVELDQAREKyVQELAAVRTDAETHLAEMR------QEAQSTSRELEVMTAKYEGAKVKVLEERQ 1428
Cdd:COG3096    366 QEEVVEEAAEQLAEAEARLEAAEEE-VDSLKSQLADYQQALDVQQtraiqyQQAVQALEKARALCGLPDLTPENAEDYLA 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1429 RFQEERQKLTAQVEQLEV------FQREQTKQVEELSKKL---TEHDQASKVQQQKLKAFQAQRGESQQEVQrLQTQLNE 1499
Cdd:COG3096    445 AFRAKEQQATEEVLELEQklsvadAARRQFEKAYELVCKIageVERSQAWQTARELLRRYRSQQALAQRLQQ-LRAQLAE 523

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1500 LQAQLSQKEQAAEhyklqmekakthydAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRH 1579
Cdd:COG3096    524 LEQRLRQQQNAER--------------LLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQ 589

                          330
                   ....*....|.
gi 1907176327 1580 LTAQVRSLEAQ 1590
Cdd:COG3096    590 LRARIKELAAR 600
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1369-1561 4.36e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 4.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1369 LEVELDQAREKyVQELAAVRTDAETHlAEMRQEAQSTSRELEVMTAKYEGAKVKVLEER-QRFQEERQKLTAQVEQLEVF 1447
Cdd:COG4913    240 AHEALEDAREQ-IELLEPIRELAERY-AAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1448 QREQTKQVEELSKKLTEHDQASKvqqQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQA-AEHYKLQMEKAKTHYD 1526
Cdd:COG4913    318 LDALREELDELEAQIRGNGGDRL---EQLEREIERLERELEERERRRARLEALLAALGLPLPAsAEEFAALRAEAAALLE 394

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1907176327 1527 AKKQQNQKLQEQL----QDLEELQKENKELRSEAERLGR 1561
Cdd:COG4913    395 ALEEELEALEEALaeaeAALRDLRRELRELEAEIASLER 433
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 320-548 4.67e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 4.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  320 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLlaerSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 399
Cdd:COG4942     28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI----AALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  400 AQLTAQLTSMtglnATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 479
Cdd:COG4942    104 EELAELLRAL----YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327  480 RQDHAQQLAIVAEAREaslrERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKA 548
Cdd:COG4942    180 LAELEEERAALEALKA----ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 262-478 4.72e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 4.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  262 AEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTR 341
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  342 VETLECERGKQ--EAQLLAERSRFE-----DEKQQLASLIADLQSSVSNLSQAKEELEQASQ---AQGAQLTAQLTSMTG 411
Cdd:COG4942     99 LEAQKEELAELlrALYRLGRQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAelaALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176327  412 LNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEA 478
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
538-704 4.78e-05

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 47.95  E-value: 4.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  538 TSVTQAQQEKAELSQKIGELHacIEASHQEQRQVQA-RVTELEAQLKAEQQKttEREKVVQEKAQLQEQLRAL-EESLKI 615
Cdd:COG2268    195 AEIIRDARIAEAEAERETEIA--IAQANREAEEAELeQEREIETARIAEAEA--ELAKKKAEERREAETARAEaEAAYEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  616 TkgslEEEKRRAADALKEQQCRATEMEAEsrslmeQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHE-LAEA 694
Cdd:COG2268    271 A----EANAEREVQRQLEIAEREREIELQ------EKEAEREEAELEADVRKPAEAEKQAAEAEAEAEAEAIRAKgLAEA 340

                          170
                   ....*....|
gi 1907176327  695 TASQHRAESE 704
Cdd:COG2268    341 EGKRALAEAW 350
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 227-607 5.29e-05

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 48.52  E-value: 5.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  227 GDLSFKVREFANHLQQLQGAFNDLIEEHS-KASQEWAEKQARLENELSTAlqDKKCLEEKNEILQGKLSQLEDQATRLQ- 304
Cdd:pfam13166   88 GEESIEIQEKIAKLKKEIKDHEEKLDAAEaNLQKLDKEKEKLEADFLDEC--WKKIKRKKNSALSEALNGFKYEANFKSr 165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  305 -----ESPAPEKGEVLGDAlqldtlkQEAAKLATDNTQLQTRVETLECerGKQEAQLLAERSRFEDEKQQLASLIADLQS 379
Cdd:pfam13166  166 llreiEKDNFNAGVLLSDE-------DRKAALATVFSDNKPEIAPLTF--NVIDFDALEKAEILIQKVIGKSSAIEELIK 236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  380 SVSNLSQAKEELEQASQAQG----------AQLTAQLTSMTGLNATLQQRD-QELASLKEQAKKEQAQMLQTMQEQEQAA 448
Cdd:pfam13166  237 NPDLADWVEQGLELHKAHLDtcpfcgqplpAERKAALEAHFDDEFTEFQNRlQKLIEKVESAISSLLAQLPAVSDLASLL 316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  449 QGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIvaeareaslrerdtarqqletveKEKDAKLESLQQQLQA 528
Cdd:pfam13166  317 SAFELDVEDIESEAEVLNSQLDGLRRALEAKRKDPFKSIEL-----------------------DSVDAKIESINDLVAS 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  529 AND--ARDNAQTSVTQAQQEKAELS---QKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQ 603
Cdd:pfam13166  374 INEliAKHNEITDNFEEEKNKAKKKlrlHLVEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEA---EIKKLREEIKELE 450


                   ....
gi 1907176327  604 EQLR 607
Cdd:pfam13166  451 AQLR 454
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1385-1614 5.56e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 5.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1385 AAVRTDAETHLAEMRQEAQSTSRELevmtAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTE 1464
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKEL----AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1465 HDQASKVQQQKLKAF--QAQRGE---------SQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQ 1533
Cdd:COG4942     95 LRAELEAQKEELAELlrALYRLGrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1534 KLQEQLQDLEELQKENKELRSEAERLGRELQQaglKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKS 1613
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEK---ELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251


                   .
gi 1907176327 1614 R 1614
Cdd:COG4942    252 K 252
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1305-1566 5.71e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 5.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1305 RAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhgllaEENRGLGERANLGRQFLEVELDQARekyVQEL 1384
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERL-----AELEYLRAALRLWFAQRRLELLEAE---LEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1385 AAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKvkvleerqrfqeerqklTAQVEQLEvfqreqtKQVEELSKKLTE 1464
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQIRGNG-----------------GDRLEQLE-------REIERLERELEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1465 HDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEhyklqmekakthyDAKKQQNQKLQEQLQDLEE 1544
Cdd:COG4913    357 RERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALE-------------EALAEAEAALRDLRRELRE 423

                          250       260
                   ....*....|....*....|..
gi 1907176327 1545 LQKENKELRSEAERLGRELQQA 1566
Cdd:COG4913    424 LEAEIASLERRKSNIPARLLAL 445
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
293-711 6.15e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.23  E-value: 6.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  293 LSQLEDQATRLQESPApEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLE---------CERGKQEAQLLAERSRF 363
Cdd:COG4717     70 LKELKELEEELKEAEE-KEEEYAELQEELEELEEELEELEAELEELREELEKLEkllqllplyQELEALEAELAELPERL 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  364 EDEKQQLASlIADLQSSVSNLSQAKEELEQASQAQGAQLT-AQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQ 442
Cdd:COG4717    149 EELEERLEE-LRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  443 -----EQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDA 517
Cdd:COG4717    228 eleqlENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  518 KLESLQQQLQAA--NDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKV 595
Cdd:COG4717    308 QALPALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEEL 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  596 VQeKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQcrATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQ 675
Cdd:COG4717    388 RA-ALEQAEEYQELKEELEELEEQLEELLGELEELLEALD--EEELEEELEELEEELEELEEELEELREELAELEAELEQ 464

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1907176327  676 LEEAhqaetealrHELAEATASQHRAESECERLIRE 711
Cdd:COG4717    465 LEED---------GELAELLQELEELKAELRELAEE 491
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 168-815 6.29e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 6.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  168 ALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAF 247
Cdd:pfam01576  447 SLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQL 526

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  248 NDL---IEEHSKASQEWAEKQARLENELSTALQdkkCLEEKNEilqgKLSQLEDQATRLQEspapekgEVLGDALQLDTL 324
Cdd:pfam01576  527 SDMkkkLEEDAGTLEALEEGKKRLQRELEALTQ---QLEEKAA----AYDKLEKTKNRLQQ-------ELDDLLVDLDHQ 592

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  325 KQeaakLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTA 404
Cdd:pfam01576  593 RQ----LVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMED 668

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  405 QLTSMTGLNATLQqrdqELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHA 484
Cdd:pfam01576  669 LVSSKDDVGKNVH----ELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKR 744

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  485 QQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEAS 564
Cdd:pfam01576  745 RQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEI 824

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  565 HQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAAD-------ALKEQQCR 637
Cdd:pfam01576  825 LAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEAriaqleeELEEEQSN 904

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  638 ATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQaETEALRHELAEATASQHRA-----ESECERLIREV 712
Cdd:pfam01576  905 TELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNK-ELKAKLQEMEGTVKSKFKSsiaalEAKIAQLEEQL 983

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  713 ESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEihsegqpgQQQSQLAQLHASLAKAIQQVQEKEVRAQK 792
Cdd:pfam01576  984 EQESRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAE--------KGNSRMKQLKRQLEEAEEEASRANAARRK 1055

                          650       660
                   ....*....|....*....|...
gi 1907176327  793 LVDDLSALQEKMAATNKEVACLK 815
Cdd:pfam01576 1056 LQRELDDATESNESMNREVSTLK 1078
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 561-1598 7.20e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 7.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  561 IEASHQEQRQVQARVTELEAQLKAEQQKTTErekVVQEKAQLQEQLRALEESLKitkgslEEEKRRAADALKEQQCRATE 640
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQ---LCEEKNALQEQLQAETELCA------EAEEMRARLAARKQELEEIL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  641 MEAESRslMEQREREQKELEQEKagrKGLEARIQQLEEaHQAETEALRHELaeatasqHRAESECERLIREVESRQKRFE 720
Cdd:pfam01576   78 HELESR--LEEEEERSQQLQNEK---KKMQQHIQDLEE-QLDEEEAARQKL-------QLEKVTTEAKIKKLEEDILLLE 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  721 ARQQEEARYGAMFQEQLmalkGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSAL 800
Cdd:pfam01576  145 DQNSKLSKERKLLEERI----SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDL 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  801 QEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASdqlgeqqgrpfssthaAVKAMEREAEQMGGELERLR 880
Cdd:pfam01576  221 QEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALK----------------KIRELEAQISELQEDLESER 284

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  881 AALIKSQgqqqeergqqerevarltqergQAQADLAQE-KAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQ 959
Cdd:pfam01576  285 AARNKAE----------------------KQRRDLGEElEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRS 342

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  960 ELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGpgtqsetagktdapgpELQALRAEISKLEQQ 1039
Cdd:pfam01576  343 HEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQA----------------ELRTLQQAKQDSEHK 406

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1040 CQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQD-HSKAEEEWKAQVA 1118
Cdd:pfam01576  407 RKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDtQELLQEETRQKLN 486

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1119 ---RGQQEAERKSSLISSLEEEVSI---LNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSS 1192
Cdd:pfam01576  487 lstRLRQLEDERNSLQEQLEEEEEAkrnVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAA 566

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1193 A---LREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQ---ELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP 1266
Cdd:pfam01576  567 AydkLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQmlaEEKAISARYAEERDRAEAEAREKETRALSLARALE 646

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1267 AKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQREL-GELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLK 1345
Cdd:pfam01576  647 EALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALeQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALK 726

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1346 KAH--GLLAEENRGLGERANLGRQF--LEVELDQAREKYVQELAAvRTDAETHLAEMRQEAQSTSRelevmtakyegAKV 1421
Cdd:pfam01576  727 AQFerDLQARDEQGEEKRRQLVKQVreLEAELEDERKQRAQAVAA-KKKLELDLKELEAQIDAANK-----------GRE 794

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1422 KVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLN--- 1498
Cdd:pfam01576  795 EAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIAsga 874

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1499 -----------ELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQqag 1567
Cdd:pfam01576  875 sgksalqdekrRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELK--- 951

                         1050      1060      1070
                   ....*....|....*....|....*....|..
gi 1907176327 1568 LKTKEAEQTCR-HLTAQVRSLEAQVAHADQQL 1598
Cdd:pfam01576  952 AKLQEMEGTVKsKFKSSIAALEAKIAQLEEQL 983
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 221-557 7.41e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.04  E-value: 7.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  221 QLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQA 300
Cdd:TIGR00618  539 QLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALL 618

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  301 TRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQ------------ 368
Cdd:TIGR00618  619 RKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQsekeqltywkem 698

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  369 --QLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQltsmtglNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQ 446
Cdd:TIGR00618  699 laQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAR-------EDALNQSLKELMHQARTVLKARTEAHFNNNEEVT 771

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  447 AAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQL 526
Cdd:TIGR00618  772 AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQL 851

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1907176327  527 QAANDARDNAQtsvtQAQQEKAELSQKIGEL 557
Cdd:TIGR00618  852 LKYEECSKQLA----QLTQEQAKIIQLSDKL 878
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
282-459 8.63e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.70  E-value: 8.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  282 LEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNT--QLQTRVETLECERGKQEAQLLAE 359
Cdd:COG3206    210 LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPViqQLRAQLAELEAELAELSARYTPN 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  360 RSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQ 439
Cdd:COG3206    290 HPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES 369

                          170       180
                   ....*....|....*....|
gi 1907176327  440 TMQEQEQAAQGLRQQVEQLS 459
Cdd:COG3206    370 LLQRLEEARLAEALTVGNVR 389
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 377-644 8.86e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 47.74  E-value: 8.86e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  377 LQSSVSNLSQAKEELEqasQAQGAQLTAQLTSMTGLNATLQQRDQELASLkEQAKKEQaqmlQTMQEQEQAAQGLRQQVE 456
Cdd:PRK10929    18 YAATAPDEKQITQELE---QAKAAKTPAQAEIVEALQSALNWLEERKGSL-ERAKQYQ----QVIDNFPKLSAELRQQLN 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  457 QLSSSLKLKEQQLEEAAKEQEaTRQDHAQQLaivAEAREASlRERDTARQ------QLETVEKEKDAKLESLQQQLQAAN 530
Cdd:PRK10929    90 NERDEPRSVPPNMSTDALEQE-ILQVSSQLL---EKSRQAQ-QEQDRAREisdslsQLPQQQTEARRQLNEIERRLQTLG 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  531 dardNAQTSVTQAQ--QEKAELSQKigelhacieashqeqrqvQARVTELE-AQLKA--EQQKTTEREKVVQEKA-QLQE 604
Cdd:PRK10929   165 ----TPNTPLAQAQltALQAESAAL------------------KALVDELElAQLSAnnRQELARLRSELAKKRSqQLDA 222

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 1907176327  605 QLRALEESLKITKgsleeeKRRAADALKEqqcraTEMEAE 644
Cdd:PRK10929   223 YLQALRNQLNSQR------QREAERALES-----TELLAE 251
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 119-672 9.20e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.86  E-value: 9.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  119 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLA----LLNEKQAASSQEPSELEE-------L 187
Cdd:pfam01576  102 QQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSkerkLLEERISEFTSNLAEEEEkakslskL 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  188 RGKNESLTVRLHETLKQC----QNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQ----LQGAFNDLIEEHSKASQ 259
Cdd:pfam01576  182 KNKHEAMISDLEERLKKEekgrQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKkeeeLQAALARLEEETAQKNN 261

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  260 ----------EWAEKQARLENE---LSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVlgdALQLDTLKQ 326
Cdd:pfam01576  262 alkkireleaQISELQEDLESEraaRNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEV---TELKKALEE 338

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  327 EAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLtaql 406
Cdd:pfam01576  339 ETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQL---- 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  407 tsmtglnatlqqrdQELASLKEQAKKEQaqmlqtmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATrqdhAQQ 486
Cdd:pfam01576  415 --------------QELQARLSESERQR-------AELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSL----ESQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  487 LAIVAEAREASLRERDTARQQLETVEKEKDakleSLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQ 566
Cdd:pfam01576  470 LQDTQELLQEETRQKLNLSTRLRQLEDERN----SLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEE 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  567 EQRQVQarvTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRAL---EESLKITKGSLEEEKRRAADALKEQQ-CRATEME 642
Cdd:pfam01576  546 GKKRLQ---RELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLlvdLDHQRQLVSNLEKKQKKFDQMLAEEKaISARYAE 622

                          570       580       590
                   ....*....|....*....|....*....|
gi 1907176327  643 AESRSLMEQREREQKELEQEKAGRKGLEAR 672
Cdd:pfam01576  623 ERDRAEAEAREKETRALSLARALEEALEAK 652
PRK11281 PRK11281
mechanosensitive channel MscK;
249-489 9.31e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 9.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  249 DLIEEHSKASQEWAEKQARLENELSTaLQDKKCLEEKNEILQ-------GKLSQLEDQATRLQESPAPEKGEVLgDALQL 321
Cdd:PRK11281    46 DALNKQKLLEAEDKLVQQDLEQTLAL-LDKIDRQKEETEQLKqqlaqapAKLRQAQAELEALKDDNDEETRETL-STLSL 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  322 DTLKQeaaKLATDNTQLQTRVETLecerGKQEAQLLAERSRFE----------DEKQQLASLIADLQSSVSNLS---QAK 388
Cdd:PRK11281   124 RQLES---RLAQTLDQLQNAQNDL----AEYNSQLVSLQTQPEraqaalyansQRLQQIRNLLKGGKVGGKALRpsqRVL 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  389 EELEQAS-QAQGAQLTAQLTSMTGLNATLQQRdQELASLKEQakkEQAQMLQTMQEqeqAAQGLRqqveqlsssLKLKEQ 467
Cdd:PRK11281   197 LQAEQALlNAQNDLQRKSLEGNTQLQDLLQKQ-RDYLTARIQ---RLEHQLQLLQE---AINSKR---------LTLSEK 260

                          250       260
                   ....*....|....*....|....*.
gi 1907176327  468 QLEEAAKEQEATRQDH----AQQLAI 489
Cdd:PRK11281   261 TVQEAQSQDEAARIQAnplvAQELEI 286
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1442-1612 9.80e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.32  E-value: 9.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1442 EQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRG---------ESQQEVQRLQTQLNELQAQLSQKEQAAE 1512
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGlvdlseeakLLLQQLSELESQLAEARAELAEAEARLA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1513 HYKLQMEKAKTH---------YDAKKQQNQKLQEQLQDLEELQKEN----KELRSEAERLGRELQQAGLKTK-EAEQTCR 1578
Cdd:COG3206    244 ALRAQLGSGPDAlpellqspvIQQLRAQLAELEAELAELSARYTPNhpdvIALRAQIAALRAQLQQEAQRILaSLEAELE 323

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1907176327 1579 HLTAQVRSLEAQVAHADQQLRDLGKFQVATDALK 1612
Cdd:COG3206    324 ALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 419-742 9.82e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.64  E-value: 9.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  419 RDQELASLKEQAKKEQAQMLQT---MQEQEQAAQGLRQQV------------EQLSSSLKLKEQQLEEAAKEQEATRQDH 483
Cdd:COG3096    783 REKRLEELRAERDELAEQYAKAsfdVQKLQRLHQAFSQFVgghlavafapdpEAELAALRQRRSELERELAQHRAQEQQL 862

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  484 AQQLaivaeareaslrerDTARQQLETVEK-EKDAKL---ESLQQQLQAANDARDNAQtsvtQAQQEKAELSQKIGELH- 558
Cdd:COG3096    863 RQQL--------------DQLKEQLQLLNKlLPQANLladETLADRLEELREELDAAQ----EAQAFIQQHGKALAQLEp 924

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  559 --ACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQ--------EKAQLQEQLRALEESLKITKGSLEEEKRRAA 628
Cdd:COG3096    925 lvAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQrrphfsyeDAVGLLGENSDLNEKLRARLEQAEEARREAR 1004

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  629 DALKEQQCRATEMEAESRSLMEQREREQKELeqekagrKGLEARIQQLEEAHQAETEAL----RHELAEAtASQHRA--- 701
Cdd:COG3096   1005 EQLRQAQAQYSQYNQVLASLKSSRDAKQQTL-------QELEQELEELGVQADAEAEERarirRDELHEE-LSQNRSrrs 1076

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 1907176327  702 ESECERLIREVESRQKRFEARQQEEaRYGAMFQEQLMALKG 742
Cdd:COG3096   1077 QLEKQLTRCEAEMDSLQKRLRKAER-DYKQEREQVVQAKAG 1116
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 241-545 1.23e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 47.36  E-value: 1.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  241 QQLQGAFNDLieEHSKASQEWAEKQARLENE---LSTALQDKKCLEEKN---------------EILQGKlSQLEDQATR 302
Cdd:PRK10929    48 EALQSALNWL--EERKGSLERAKQYQQVIDNfpkLSAELRQQLNNERDEprsvppnmstdaleqEILQVS-SQLLEKSRQ 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  303 LQESPapEKGEVLGDAL-QLDTLKQEAAKLATD-------------------NTQLQT-------RVETLECergkqeAQ 355
Cdd:PRK10929   125 AQQEQ--DRAREISDSLsQLPQQQTEARRQLNEierrlqtlgtpntplaqaqLTALQAesaalkaLVDELEL------AQ 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  356 LLAE------RSRFEDEKQQLASLIADLQSSVSNL-SQAKEELEQASQA------QGAQLTAQLTSMTGLNATLQQrdqe 422
Cdd:PRK10929   197 LSANnrqelaRLRSELAKKRSQQLDAYLQALRNQLnSQRQREAERALEStellaeQSGDLPKSIVAQFKINRELSQ---- 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  423 laslkeqAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRqdhaQQLAIVAEAREASLRERD 502
Cdd:PRK10929   273 -------ALNQQAQRMDLIASQQRQAASQTLQVRQALNTLREQSQWLGVSNALGEALR----AQVARLPEMPKPQQLDTE 341

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1907176327  503 TARQQLETVekekdaKLESLQQQLQAANDARDNAQTSVTQAQQ 545
Cdd:PRK10929   342 MAQLRVQRL------RYEDLLNKQPQLRQIRQADGQPLTAEQN 378
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
372-812 1.32e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 46.82  E-value: 1.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  372 SLIADLQSSVSNLSQAKEELEQASQAQGAQLtAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGL 451
Cdd:COG5278     76 SFLEPYEEARAEIDELLAELRSLTADNPEQQ-ARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEI 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  452 RQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAAND 531
Cdd:COG5278    155 RARLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALEL 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  532 ARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEE 611
Cdd:COG5278    235 LAALALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAA 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  612 SLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHEL 691
Cdd:COG5278    315 AAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  692 AEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQ 771
Cdd:COG5278    395 IAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAAL 474

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1907176327  772 LHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVA 812
Cdd:COG5278    475 AALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEA 515
PRK09039 PRK09039
peptidoglycan -binding protein;
364-529 1.35e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.50  E-value: 1.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  364 EDEKQQLASLIADLQSSVSNLSQAKEELeqasQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQE 443
Cdd:PRK09039    52 DSALDRLNSQIAELADLLSLERQGNQDL----QDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDS 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  444 QEQAAQGLRQQVEQLSsslklkeQQLeeaakeqEATRqdhaQQLAIVAEAREASlrerdtarqqlETVEKEKDAKLESLQ 523
Cdd:PRK09039   128 EKQVSARALAQVELLN-------QQI-------AALR----RQLAALEAALDAS-----------EKRDRESQAKIADLG 178


                   ....*.
gi 1907176327  524 QQLQAA 529
Cdd:PRK09039   179 RRLNVA 184
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1119-1562 1.36e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 47.04  E-value: 1.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1119 RGQQEAERKSS-LISSLEEEVSilnrQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSAL--- 1194
Cdd:pfam05557   27 RARIELEKKASaLKRQLDRESD----RNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLada 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1195 REEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqql 1274
Cdd:pfam05557  103 REVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAEQRI---------- 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1275 qaeqaaaekrfrEELEQSKQAAGGLQAELMRAQRELGelgslrqKIVEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEE 1354
Cdd:pfam05557  173 ------------KELEFEIQSQEQDSEIVKNSKSELA-------RIPELEKELERLREHN----KHLNENIENKLLLKEE 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1355 NRGLgeRANLGRQfleveldqarEKYVQELAAVRTDAEtHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQR---FQ 1431
Cdd:pfam05557  230 VEDL--KRKLERE----------EKYREEAATLELEKE-KLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQReivLK 296

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1432 EERQKLTAQVEQLEVFQRE-------QTKQVEELSKKLTEHD-QASKVQQQKLKAFQAQRG------------------- 1484
Cdd:pfam05557  297 EENSSLTSSARQLEKARREleqelaqYLKKIEDLNKKLKRHKaLVRRLQRRVLLLTKERDGyrailesydkeltmsnysp 376

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1485 -------ESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQL--QDLEELQKENKELRSE 1555
Cdd:pfam05557  377 qllerieEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYskEEVDSLRRKLETLELE 456


                   ....*..
gi 1907176327 1556 AERLGRE 1562
Cdd:pfam05557  457 RQRLREQ 463
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1283-1624 1.51e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.98  E-value: 1.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1283 KRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGER- 1361
Cdd:PRK03918   182 EKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKi 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1362 ANLGRQFLEVELD-QAREKYVQELAAVRTDAETHlaemrqeaqstsRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQ 1440
Cdd:PRK03918   262 RELEERIEELKKEiEELEEKVKELKELKEKAEEY------------IKLSEFYEEYLDELREIEKRLSRLEEEINGIEER 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1441 VEQLEvfqrEQTKQVEELSKKLTEHDQASKVQQQKLKAFQaqrgesqqEVQRLQTQLNELQAQLSQKEqaAEHYKLQMEK 1520
Cdd:PRK03918   330 IKELE----EKEERLEELKKKLKELEKRLEELEERHELYE--------EAKAKKEELERLKKRLTGLT--PEKLEKELEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1521 AKThydAKKQQNQKLQEQLQDLEELQKENKELRSEAERL----------GRELQQaglktKEAEQTCRHLTAQVRSLEAQ 1590
Cdd:PRK03918   396 LEK---AKEEIEEEISKITARIGELKKEIKELKKAIEELkkakgkcpvcGRELTE-----EHRKELLEEYTAELKRIEKE 467

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1907176327 1591 VAHADQQLRDLGKFQVATDALKSREPQVKPQLDL 1624
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKKESELIKLKEL 501
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 480-1333 1.55e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 1.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  480 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLES---LQQQLQAANDARDNAQTSVtqAQQEKAElsqkige 556
Cdd:COG3096    280 RRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSAResdLEQDYQAASDHLNLVQTAL--RQQEKIE------- 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  557 lhacieashqeqrQVQARVTELEAQLKAEQQKTTEREkvvQEKAQLQEQLRALEESLKITKGSLEEEKRraadALKEQQC 636
Cdd:COG3096    351 -------------RYQEDLEELTERLEEQEEVVEEAA---EQLAEAEARLEAAEEEVDSLKSQLADYQQ----ALDVQQT 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  637 RATEMEAESRSLmeqrEREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRH-----ELAEATASQHRAESEC-ERLIR 710
Cdd:COG3096    411 RAIQYQQAVQAL----EKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLEleqklSVADAARRQFEKAYELvCKIAG 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  711 EVESRQKRFEARQQ-EEARYGAMFQEQLMALKgektgQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVR 789
Cdd:COG3096    487 EVERSQAWQTARELlRRYRSQQALAQRLQQLR-----AQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAE 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  790 AQKLVDDLSALQEkmAATNKEVACLKTLVLKAGEQQETASlellKEPP-RAANRASDQLGEQQGRPFSSTHAAVKAMERE 868
Cdd:COG3096    562 LEAQLEELEEQAA--EAVEQRSELRQQLEQLRARIKELAA----RAPAwLAAQDALERLREQSGEALADSQEVTAAMQQL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  869 aeqmggeLERLRAALIkSQGQQQEERGQQEREVARLTQERGQAQADLAQekaakaeLEMRLQNTLNEQRVEFAALQEA-- 946
Cdd:COG3096    636 -------LEREREATV-ERDELAARKQALESQIERLSQPGGAEDPRLLA-------LAERLGGVLLSEIYDDVTLEDApy 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  947 -------LAHAL---------------------------------------TEKEGTDqeLAKLRGQE------------ 968
Cdd:COG3096    701 fsalygpARHAIvvpdlsavkeqlagledcpedlyliegdpdsfddsvfdaEELEDAV--VVKLSDRQwrysrfpevplf 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  969 ---------AAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASgedasgPGTQSETAGKTDaPGPELQALRAEISKLEQQ 1039
Cdd:COG3096    779 graarekrlEELRAERDELAEQYAKASFDVQKLQRLHQAFSQF------VGGHLAVAFAPD-PEAELAALRQRRSELERE 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1040 cqqqqqqveglthsLKSERACRAEQDKALETLQGQLEEKARELGHnqaASASAQRELQALRAKAQDHSKAEEEWKAQVAR 1119
Cdd:COG3096    852 --------------LAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQ---ANLLADETLADRLEELREELDAAQEAQAFIQQ 914

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1120 GQQEAERksslissLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQ 1199
Cdd:COG3096    915 HGKALAQ-------LEPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGENSDLNE 987

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1200 SLREEVEkqrvvsensrqelasQAERA-EELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLP-----AKHLCQQ 1273
Cdd:COG3096    988 KLRARLE---------------QAEEArREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQeleelGVQADAE 1052

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1274 LQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRelgELGSLRQKIVEQERAAQQLRAE 1333
Cdd:COG3096   1053 AEERARIRRDELHEELSQNRSRRSQLEKQLTRCEA---EMDSLQKRLRKAERDYKQEREQ 1109
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 516-698 1.60e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.36  E-value: 1.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  516 DAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKV 595
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  596 VQEK--------------------------AQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLM 649
Cdd:COG3883     95 LYRSggsvsyldvllgsesfsdfldrlsalSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1907176327  650 EQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQ 698
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
46 PHA02562
endonuclease subunit; Provisional
 411-633 1.79e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.55  E-value: 1.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  411 GLNATLQQRDQELASLKEQAK-------------KEQAQMLQTMQEQE-QAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQ 476
Cdd:PHA02562   178 ELNQQIQTLDMKIDHIQQQIKtynknieeqrkknGENIARKQNKYDELvEEAKTIKAEIEELTDELLNLVMDIEDPSAAL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  477 EATRQDHAQQLAIVAE-AREASLRERD----TARQQLET----VEKEKDaKLESLQQQLQAANDARDNAQ---TSVTQAQ 544
Cdd:PHA02562   258 NKLNTAAAKIKSKIEQfQKVIKMYEKGgvcpTCTQQISEgpdrITKIKD-KLKELQHSLEKLDTAIDELEeimDEFNEQS 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  545 QEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKaeqQKTTEREKVVQEKaqlqeqlraleESLKITKGSLEEEK 624
Cdd:PHA02562   337 KKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFV---DNAEELAKLQDEL-----------DKIVKTKSELVKEK 402

                          250
                   ....*....|..
gi 1907176327  625 RR---AADALKE 633
Cdd:PHA02562   403 YHrgiVTDLLKD 414
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 593-1382 1.85e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.65  E-value: 1.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  593 EKVVQEKAQlqeQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEkagRKGLEAR 672
Cdd:pfam15921   77 ERVLEEYSH---QVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDL---RNQLQNT 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  673 IQQLEEAHQAETEALRHELAEATASQHRAESEcERLIREVESRQKRFEarqqEEARYGAMFQEQLMALKGEKTGQEVQEE 752
Cdd:pfam15921  151 VHELEAAKCLKEDMLEDSNTQIEQLRKMMLSH-EGVLQEIRSILVDFE----EASGKKIYEHDSMSTMHFRSLGSAISKI 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  753 AVEIHSE-----GQPGQQQSQLAQLHASLAKAIQQV-QEKEVRAQKLVDD----LSALQEKMAATNKEVACLKTlvlkag 822
Cdd:pfam15921  226 LRELDTEisylkGRIFPVEDQLEALKSESQNKIELLlQQHQDRIEQLISEheveITGLTEKASSARSQANSIQS------ 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  823 eqqetaSLELLKEPPRAANrasdQLGEQQGRPFSSTHAAVKAMEREAEQM-GGELERLRAALIKSQgqqqeergqqerev 901
Cdd:pfam15921  300 ------QLEIIQEQARNQN----SMYMRQLSDLESTVSQLRSELREAKRMyEDKIEELEKQLVLAN-------------- 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  902 ARLTQERGQaQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQT 981
Cdd:pfam15921  356 SELTEARTE-RDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEAL 434

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  982 LEQLKIQlVKKEKEHPAGGASGEDASGPGTQSETAgKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACR 1061
Cdd:pfam15921  435 LKAMKSE-CQGQMERQMAAIQGKNESLEKVSSLTA-QLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAI 512

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1062 AEQDKALETLQGQLEEKARELGHNQAAS---ASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEV 1138
Cdd:pfam15921  513 EATNAEITKLRSRVDLKLQELQHLKNEGdhlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEK 592

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1139 SILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREevqsLREEVEKQRVVSENSRQE 1218
Cdd:pfam15921  593 AQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKD----IKQERDQLLNEVKTSRNE 668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1219 LASQAERAEELGQELKAWQEKFfqkEQALSALQLEHTSTQalvSELlpakhlcqqlqAEQAAAEKRFREELEQSKQAAGG 1298
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEM---ETTTNKLKMQLKSAQ---SEL-----------EQTRNTLKSMEGSDGHAMKVAMG 731

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1299 LQAELMrAQRelGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLA-EENRGLGERANLGRQ---------F 1368
Cdd:pfam15921  732 MQKQIT-AKR--GQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVAtEKNKMAGELEVLRSQerrlkekvaN 808

                          810
                   ....*....|....
gi 1907176327 1369 LEVELDQAREKYVQ 1382
Cdd:pfam15921  809 MEVALDKASLQFAE 822
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 563-812 1.86e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 1.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  563 ASHQEQRQVQARVTELEAQLKAEQQkttEREKVVQEKAQLQEQLRALEESLKitkgsleeekrRAADALKEQQCRATEME 642
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEK---ELAALKKEEKALLKQLAALERRIA-----------ALARRIRALEQELAALE 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  643 AESRSLMEQREREQKELEQEkagRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESEcERLIREVESRQKRFEAR 722
Cdd:COG4942     83 AELAELEKEIAELRAELEAQ---KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL-KYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  723 QQEEARYGAMFQEQLMALKGEKTGQEVQEEAVeihsEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQE 802
Cdd:COG4942    159 LAELAALRAELEAERAELEALLAELEEERAAL----EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234

                          250
                   ....*....|
gi 1907176327  803 KMAATNKEVA 812
Cdd:COG4942    235 EAAAAAERTP 244
mukB PRK04863
chromosome partition protein MukB;
1180-1565 2.09e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.49  E-value: 2.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1180 TASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKfFQKEQALSALQLEHTSTQA 1259
Cdd:PRK04863   277 HANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDH-LNLVQTALRQQEKIERYQA 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1260 LVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELgslrQKIVEQERAAQQL--RAEKASY 1337
Cdd:PRK04863   356 DLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQ----QTRAIQYQQAVQAleRAKQLCG 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1338 AEQLSmLKKAHGLLAE---ENRGLGERANLGRQFLEVElDQAREKYVQELAAVRTDAethlAEM-RQEAQSTSRELEVMT 1413
Cdd:PRK04863   432 LPDLT-ADNAEDWLEEfqaKEQEATEELLSLEQKLSVA-QAAHSQFEQAYQLVRKIA----GEVsRSEAWDVARELLRRL 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1414 AKYEGAKVKVLEERQRFQEERQKLTAQ---VEQLEVFQREQTKQV---EELSKKLTEHDQaskvQQQKLKAFQAQRGESQ 1487
Cdd:PRK04863   506 REQRHLAEQLQQLRMRLSELEQRLRQQqraERLLAEFCKRLGKNLddeDELEQLQEELEA----RLESLSESVSEARERR 581

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327 1488 QEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQ 1565
Cdd:PRK04863   582 MALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDE 659
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
462-816 2.16e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 45.66  E-value: 2.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  462 LKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVT 541
Cdd:COG4372     18 LRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  542 QAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREkvvQEKAQLQEQLRALEESLKITKGSLE 621
Cdd:COG4372     98 QAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAERE---EELKELEEQLESLQEELAALEQELQ 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  622 EEKRRAADALKEQQCRATEMEAEsrSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRA 701
Cdd:COG4372    175 ALSEAEAEQALDELLKEANRNAE--KEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELL 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  702 ESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQ 781
Cdd:COG4372    253 EEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELAL 332

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 1907176327  782 QVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKT 816
Cdd:COG4372    333 AILLAELADLLQLLLVGLLDNDVLELLSKGAEAGV 367
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 516-610 2.34e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 45.49  E-value: 2.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  516 DAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQV-QARVTELEAQLK-AEQQKTTERE 593
Cdd:TIGR04320  260 QAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTaQNNLATAQAALAnAEARLAKAKE 339

                           90
                   ....*....|....*..
gi 1907176327  594 KVVQEKAQLQEQLRALE 610
Cdd:TIGR04320  340 ALANLNADLAKKQAALD 356
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1375-1597 2.37e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1375 QAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQ 1454
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1455 VEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQK 1534
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907176327 1535 LQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTcrhLTAQVRSLEAQVAHADQQ 1597
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE---LEALIARLEAEAAAAAER 242
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1480-1602 2.72e-04

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 46.10  E-value: 2.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1480 QAQRGESQQEVQRLQTQLnELQAQlsQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEA-ER 1558
Cdd:PRK11448   141 ENLLHALQQEVLTLKQQL-ELQAR--EKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERkQK 217

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1907176327 1559 LGRELQQAGLKTKEAEQTCRHLTaqvrsleaqvahaDQQLRDLG 1602
Cdd:PRK11448   218 RKEITDQAAKRLELSEEETRILI-------------DQQLRKAG 248
PRK11637 PRK11637
AmiB activator; Provisional
 356-668 2.85e-04

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 45.45  E-value: 2.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  356 LLAERSRFEDEKQQLASLIADLqssvsnlsQAKEELEQASQaqgaqltaqltsmtglnatlQQRDQELASLKEQaKKEQA 435
Cdd:PRK11637    35 LCAFSAHASDNRDQLKSIQQDI--------AAKEKSVRQQQ--------------------QQRASLLAQLKKQ-EEAIS 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  436 QMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQleeaakeqeatrqdHAQQLAIVAEAREASLRERDTARQQLeTVEKEK 515
Cdd:PRK11637    86 QASRKLRETQNTLNQLNKQIDELNASIAKLEQQ--------------QAAQERLLAAQLDAAFRQGEHTGLQL-ILSGEE 150

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  516 DAKLESLQQQLQAANDARdnaQTSVTQAQQEKAELSQKIGELhaciEASHQEQRQVqarVTELEAQLKAEQQKTTEREKV 595
Cdd:PRK11637   151 SQRGERILAYFGYLNQAR---QETIAELKQTREELAAQKAEL----EEKQSQQKTL---LYEQQAQQQKLEQARNERKKT 220

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907176327  596 vqekaqlqeqLRALEESLKITKGSLEEEKRRAAdALKEQQCRAtEMEAESRSLMEQREREQKELEQEKAGRKG 668
Cdd:PRK11637   221 ----------LTGLESSLQKDQQQLSELRANES-RLRDSIARA-EREAKARAEREAREAARVRDKQKQAKRKG 281
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1075-1598 3.34e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 3.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1075 LEEKARElGHNQAASASAQRELQALRAKAQD-----HSKAEEEWKAQVARGQQEAERK-SSLISSLEEEVSILNRQVLEK 1148
Cdd:pfam15921  283 LTEKASS-ARSQANSIQSQLEIIQEQARNQNsmymrQLSDLESTVSQLRSELREAKRMyEDKIEELEKQLVLANSELTEA 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1149 EGESKELKRLVVAESEKSQKL----EERLRLLQVETASNSaRAAERSSA-------LREEVQSLREEVEKQRVVSENSRQ 1217
Cdd:pfam15921  362 RTERDQFSQESGNLDDQLQKLladlHKREKELSLEKEQNK-RLWDRDTGnsitidhLRRELDDRNMEVQRLEALLKAMKS 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1218 ELASQAER--------------AEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEK 1283
Cdd:pfam15921  441 ECQGQMERqmaaiqgkneslekVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1284 RFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEkasyAEQLSMLKKAHGLLAeeNRGLGERAN 1363
Cdd:pfam15921  521 KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQ----IENMTQLVGQHGRTA--GAMQVEKAQ 594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1364 LGRQFLEVELDqarekyVQELAAVRTDAETHLAEMrqEAQSTSRELEvmTAKYEGAKVKVLEERQRFQEERQKLTAQVEQ 1443
Cdd:pfam15921  595 LEKEINDRRLE------LQEFKILKDKKDAKIREL--EARVSDLELE--KVKLVNAGSERLRAVKDIKQERDQLLNEVKT 664

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1444 LEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAfqaQRGESQQEVQRLQTQLNELQAQLSQKEQAAehykLQMEKAKT 1523
Cdd:pfam15921  665 SRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKM---QLKSAQSELEQTRNTLKSMEGSDGHAMKVA----MGMQKQIT 737

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327 1524 hydAKKQQNQKLQEQLQDLEEL----QKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQL 1598
Cdd:pfam15921  738 ---AKRGQIDALQSKIQFLEEAmtnaNKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVAL 813
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 152-831 3.51e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 3.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  152 EKDAQIAMMQQRIDHLALLNEKQAASSQEPseleelrgkneslTVRLHETLKQCQNLKTEKSQMDRKISQLSEengDLSF 231
Cdd:pfam15921   82 EYSHQVKDLQRRLNESNELHEKQKFYLRQS-------------VIDLQTKLQEMQMERDAMADIRRRESQSQE---DLRN 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  232 KVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLE---NELSTALQDKKCLEEKNEILQGKLSQLEDQAT------- 301
Cdd:pfam15921  146 QLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLgsaiski 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  302 --RLQESPAPEKGEVLGDALQLDTLKQEAaklatdntqlQTRVETLECERGKQEAQLLAERsrfEDEKQQLASLIADLQS 379
Cdd:pfam15921  226 lrELDTEISYLKGRIFPVEDQLEALKSES----------QNKIELLLQQHQDRIEQLISEH---EVEITGLTEKASSARS 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  380 SVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQE--------LASLKEQAKKEQAQMLQTMQEQEQAAQ-- 449
Cdd:pfam15921  293 QANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREakrmyedkIEELEKQLVLANSELTEARTERDQFSQes 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  450 -GLRQQVEQLSSSLKLKEQQLeEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLE----TVEKEKDAKLESLQQ 524
Cdd:pfam15921  373 gNLDDQLQKLLADLHKREKEL-SLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEallkAMKSECQGQMERQMA 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  525 QLQAANDARDNAQTSVTQAQQEKAELSQKIGELHA---CIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQ 601
Cdd:pfam15921  452 AIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAkkmTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  602 LQEQLRALEESLKITKGSLE------EEKRRAADALKEQQCRATE-----------MEAESRSLMEQREREQKELEQEKA 664
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEalklqmAEKDKVIEILRQQIENMTQlvgqhgrtagaMQVEKAQLEKEINDRRLELQEFKI 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  665 GRKGLEARIQQLeEAHQAETEALRHELAEATASQHRA----ESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMAL 740
Cdd:pfam15921  612 LKDKKDAKIREL-EARVSDLELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEM 690

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  741 KGEKTGQEVQEEAVEIHSEgqpgQQQSQLAQLHASLAKAI-------QQVQEKEVRAQKLVDDLSALQEKMAATNKEVAC 813
Cdd:pfam15921  691 ETTTNKLKMQLKSAQSELE----QTRNTLKSMEGSDGHAMkvamgmqKQITAKRGQIDALQSKIQFLEEAMTNANKEKHF 766

                          730
                   ....*....|....*...
gi 1907176327  814 LKTLVLKAGEQQETASLE 831
Cdd:pfam15921  767 LKEEKNKLSQELSTVATE 784
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1054-1250 3.57e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 45.82  E-value: 3.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1054 LKSERACRAEQDKA------LETLQGQLEEKARELghnqaasASAQRELQALRAKAQDHSKAeeewkaQVARGQQEAERK 1127
Cdd:PRK10929   119 LEKSRQAQQEQDRAreisdsLSQLPQQQTEARRQL-------NEIERRLQTLGTPNTPLAQA------QLTALQAESAAL 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1128 SSLISSLE-EEVSILNRQvlekegeskELKRLvvaESEKSQKLEERL--RLLQVETASNSAR------AAERSSALREEV 1198
Cdd:PRK10929   186 KALVDELElAQLSANNRQ---------ELARL---RSELAKKRSQQLdaYLQALRNQLNSQRqreaerALESTELLAEQS 253

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907176327 1199 QSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSAL 1250
Cdd:PRK10929   254 GDLPKSIVAQFKINRELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTL 305
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1189-1603 4.68e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 4.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1189 ERSSALREEVQSLREEVEkqrvvsensrqELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEllpak 1268
Cdd:PRK02224   206 ERLNGLESELAELDEEIE-----------RYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAE----- 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1269 hlcqqlqaeQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGeLGSLRQKIVEQERAAqqLRAEKASYAEQLSMLKKAH 1348
Cdd:PRK02224   270 ---------TEREREELAEEVRDLRERLEELEEERDDLLAEAG-LDDADAEAVEARREE--LEDRDEELRDRLEECRVAA 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1349 GLLAEENRGLGERANLgrqfLEVELDQAREKyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKV---KVLE 1425
Cdd:PRK02224   338 QAHNEEAESLREDADD----LEERAEELREE-AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVdlgNAED 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1426 ERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLS 1505
Cdd:PRK02224   413 FLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVE 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1506 QKEQAAEHYKlQMEKAKTHYDAKKQQNQKLQEQLQD----LEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLT 1581
Cdd:PRK02224   493 EVEERLERAE-DLVEAEDRIERLEERREDLEELIAErretIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR 571

                          410       420
                   ....*....|....*....|..
gi 1907176327 1582 AQVRSLEAQVAHADQQLRDLGK 1603
Cdd:PRK02224   572 EEVAELNSKLAELKERIESLER 593
KpsE COG3524
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
353-492 5.21e-04

Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442746 [Multi-domain]  Cd Length: 370  Bit Score: 44.46  E-value: 5.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  353 EAQLLAERSRFEDEKQQLASL-----IADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLK 427
Cdd:COG3524    183 EEEVERAEERLRDAREALLAFrnrngILDPEATAEALLQLIATLEGQLAELEAELAALRSYLSPNSPQVRQLRRRIAALE 262

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327  428 EQAKKEQAQMlqTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQ---LAIVAE 492
Cdd:COG3524    263 KQIAAERARL--TGASGGDSLASLLAEYERLELEREFAEKAYTSALAALEQARIEAARQqryLAVIVQ 328
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 338-711 5.34e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.89  E-value: 5.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  338 LQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQaqgaQLTAQLTSMTGLNATLQ 417
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELR----QSREKHEELEEKYKELS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  418 QRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKeQEATRQDHAQQLAIVAEAREAS 497
Cdd:pfam07888  108 ASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGA-QRKEEEAERKQLQAKLQQTEEE 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  498 LRERDTARQQLETVEKEKDAKLESLQqqlqaanDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTE 577
Cdd:pfam07888  187 LRSLSKEFQELRNSLAQRDTQVLQLQ-------DTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEE 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  578 LEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESrslmeqrEREQK 657
Cdd:pfam07888  260 LSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAEL-------QRLEE 332

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907176327  658 ELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIRE 711
Cdd:pfam07888  333 RLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAE 386
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 416-585 5.38e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.76  E-value: 5.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  416 LQQRDQELASLKEQAKKEQAQmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEARE 495
Cdd:COG1579     12 LQELDSELDRLEHRLKELPAE-LAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  496 ASLRERD-----TARQQLETVEKEKDAKLESLQQQLQAANDARDnaqtsvtqaqQEKAELSQKIGELHACIEASHQEQRQ 570
Cdd:COG1579     91 YEALQKEieslkRRISDLEDEILELMERIEELEEELAELEAELA----------ELEAELEEKKAELDEELAELEAELEE 160

                          170
                   ....*....|....*
gi 1907176327  571 VQARVTELEAQLKAE 585
Cdd:COG1579    161 LEAEREELAAKIPPE 175
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
265-479 5.49e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 5.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  265 QARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQES----PAPEKGEVLGDalQLDTLKQEAAKLATDNTQLQT 340
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKnglvDLSEEAKLLLQ--QLSELESQLAEARAELAEAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  341 RVETLE--CERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLS-------QAKEELEQASQAQGAQLTAQLTSMTG 411
Cdd:COG3206    241 RLAALRaqLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTpnhpdviALRAQIAALRAQLQQEAQRILASLEA 320

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327  412 LNATLQQRDQELASLKEQAKKEqaqmLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 479
Cdd:COG3206    321 ELEALQAREASLQAQLAQLEAR----LAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALT 384
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1061-1265 5.54e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 5.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1061 RAEQDKALETLQGQLEEKARELghnqaasASAQRELQALRAKAQdhskaeeewkaqVARGQQEAERKSSLISSLEEEVSI 1140
Cdd:COG3206    170 REEARKALEFLEEQLPELRKEL-------EEAEAALEEFRQKNG------------LVDLSEEAKLLLQQLSELESQLAE 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1141 LNRQVLEKEGESKELKRLV---------VAESEKSQKLEERLRLLQVETASNSARAAERSS---ALREEVQSLREEVEKQ 1208
Cdd:COG3206    231 ARAELAEAEARLAALRAQLgsgpdalpeLLQSPVIQQLRAQLAELEAELAELSARYTPNHPdviALRAQIAALRAQLQQE 310

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176327 1209 -RVVSENSRQELASQAERAEELGQELKAWQEKFF---QKEQALSALQLEHTSTQALVSELL 1265
Cdd:COG3206    311 aQRILASLEAELEALQAREASLQAQLAQLEARLAelpELEAELRRLEREVEVARELYESLL 371
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
451-588 6.59e-04

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 44.27  E-value: 6.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  451 LRQQVEQLSSSLKLKEQQLEeAAKEQEATRQDHAQQLAIVAEAREaslrERDTARQQLETVEKEKDAKLESlQQQLQAAN 530
Cdd:COG1566     81 LQAALAQAEAQLAAAEAQLA-RLEAELGAEAEIAAAEAQLAAAQA----QLDLAQRELERYQALYKKGAVS-QQELDEAR 154

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327  531 DARDNAQTSVTQAQqekAELSQKIGELhacieASHQEQRQVQARVTELEAQLKAEQQK 588
Cdd:COG1566    155 AALDAAQAQLEAAQ---AQLAQAQAGL-----REEEELAAAQAQVAQAEAALAQAELN 204
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 289-664 6.85e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.81  E-value: 6.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  289 LQGKLSQLEDQATRL-----QESPAPEKGEVLGDALQLDtlKQEAAKLATDNTQLQTRVETLECERGKQEAQLLaersRF 363
Cdd:pfam10174  298 LSKKESELLALQTKLetltnQNSDCKQHIEVLKESLTAK--EQRAAILQTEVDALRLRLEEKESFLNKKTKQLQ----DL 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  364 EDEKQQLASLIAD--------------LQSSVSNLSQA-------KEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQE 422
Cdd:pfam10174  372 TEEKSTLAGEIRDlkdmldvkerkinvLQKKIENLQEQlrdkdkqLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERI 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  423 LASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAakeqeatrQDHAQQLAivaeareASLRERD 502
Cdd:pfam10174  452 IERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDL--------KEHASSLA-------SSGLKKD 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  503 TARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTsvtqaqqeKAELSQKIGELHACIEASHQEQRQVQARVTELEAQL 582
Cdd:pfam10174  517 SKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRT--------NPEINDRIRLLEQEVARYKEESGKAQAEVERLLGIL 588

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  583 K-AEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESR-----SLMEQREREQ 656
Cdd:pfam10174  589 ReVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQqlqleELMGALEKTR 668


                   ....*...
gi 1907176327  657 KELEQEKA 664
Cdd:pfam10174  669 QELDATKA 676
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 486-750 7.25e-04

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 44.29  E-value: 7.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  486 QLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASH 565
Cdd:pfam19220   31 QLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALREAEAAKEELR 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  566 QEQRQVQARVTELEAQLKAEqqkTTEREKVVQEKAQLQEQLRALEESLKITKGSL----------EEEKRRAADALKEQQ 635
Cdd:pfam19220  111 IELRDKTAQAEALERQLAAE---TEQNRALEEENKALREEAQAAEKALQRAEGELatarerlallEQENRRLQALSEEQA 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  636 CRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEAT----ASQHRAES------EC 705
Cdd:pfam19220  188 AELAELTRRLAELETQLDATRARLRALEGQLAAEQAERERAEAQLEEAVEAHRAERASLRmkleALTARAAAteqllaEA 267

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1907176327  706 ERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQ 750
Cdd:pfam19220  268 RNQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQ 312
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 367-470 7.32e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 43.95  E-value: 7.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  367 KQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQltsmTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQ 446
Cdd:TIGR04320  253 PNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAY----AAAQAALATAQKELANAQAQALQTAQNNLATAQAALA 328

                           90       100
                   ....*....|....*....|....*...
gi 1907176327  447 AAQG----LRQQVEQLSSSLKLKEQQLE 470
Cdd:TIGR04320  329 NAEArlakAKEALANLNADLAKKQAALD 356
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1431-1601 7.34e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 7.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1431 QEERQKLTAQVEQLEVFQREQ----------TKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNEL 1500
Cdd:TIGR04523  359 SEKQRELEEKQNEIEKLKKENqsykqeiknlESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1501 QAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQL----QDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQT 1576
Cdd:TIGR04523  439 NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSInkikQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK 518

                          170       180
                   ....*....|....*....|....*
gi 1907176327 1577 CRHLTAQVRSLEAQVAHADQQLRDL 1601
Cdd:TIGR04523  519 ISSLKEKIEKLESEKKEKESKISDL 543
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1445-1565 7.38e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.46  E-value: 7.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1445 EVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQrgesqqeVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTH 1524
Cdd:COG2433    384 ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQ-------VERLEAEVEELEAELEEKDERIERLERELSEARSE 456

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1907176327 1525 YDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQ 1565
Cdd:COG2433    457 ERREIRKDREISRLDREIERLERELEEERERIEELKRKLER 497
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 370-745 7.70e-04

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 44.29  E-value: 7.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  370 LASLIADLQSSVSNLSQAKEELEQAsQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQ 449
Cdd:pfam19220   22 LRSLKADFSQLIEPIEAILRELPQA-KSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALR 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  450 GLRQQVEQLSSSLKLKEQQLEEAAKeqeatrqdhaqQLAIVAEAREASLRERDTARQQLETVEK---EKDAKLESLQQQL 526
Cdd:pfam19220  101 EAEAAKEELRIELRDKTAQAEALER-----------QLAAETEQNRALEEENKALREEAQAAEKalqRAEGELATARERL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  527 QAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQAR-VTELEAQLKAEQQKTTEREKVVQEKAQLQEQ 605
Cdd:pfam19220  170 ALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEGQlAAEQAERERAEAQLEEAVEAHRAERASLRMK 249

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  606 LRALEESLKITKgSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETE 685
Cdd:pfam19220  250 LEALTARAAATE-QLLAEARNQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQFQEMQRARAELEERAE 328

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  686 ALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKT 745
Cdd:pfam19220  329 MLTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAALEQANRRLKEELQRERAERA 388
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1425-1566 8.39e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.99  E-value: 8.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1425 EERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGE--SQQEVQRLQTQLNELQA 1502
Cdd:COG1579     24 HRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrNNKEYEALQKEIESLKR 103

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327 1503 QLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLE-ELQKENKELRSEAERLGRELQQA 1566
Cdd:COG1579    104 RISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKaELDEELAELEAELEELEAEREEL 168
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 421-725 8.47e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.12  E-value: 8.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  421 QELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKL---KEQQLEEAAKEQEATRQDHAQQLAIVAEAREAS 497
Cdd:pfam07888   48 QAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQsreKHEELEEKYKELSASSEELSEEKDALLAQRAAH 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  498 ---LRERDTARQQLETVEKEKDAKLESLQQ-------QLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQE 567
Cdd:pfam07888  128 earIRELEEDIKTLTQRVLERETELERMKErakkagaQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQ 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  568 QRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEE-------------EKRRAADALKEQ 634
Cdd:pfam07888  208 VLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSmaaqrdrtqaelhQARLQAAQLTLQ 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  635 QCRATEMEAESRSLMEQ-REREQKELEQEKAGRKGLEARIQQLEEAHQAET---EALRHELAEATASQHRAESECERLIR 710
Cdd:pfam07888  288 LADASLALREGRARWAQeRETLQQSAEADKDRIEKLSAELQRLEERLQEERmerEKLEVELGREKDCNRVQLSESRRELQ 367

                          330
                   ....*....|....*
gi 1907176327  711 EVESRQKRFEARQQE 725
Cdd:pfam07888  368 ELKASLRVAQKEKEQ 382
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1165-1615 8.80e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.57  E-value: 8.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1165 KSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERA--EELGQELKAWQEKFFQ 1242
Cdd:TIGR00618  195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLkkQQLLKQLRARIEELRA 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1243 KEQALSALQLEHTSTQALVSELLPAKHL--CQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKI 1320
Cdd:TIGR00618  275 QEAVLEETQERINRARKAAPLAAHIKAVtqIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1321 VEQERAAQQLRAEKASYAEQLSMLKKAHGlLAEENRGLGERANLGRQFLEVE---------LDQAREKYVQELAAVRTDA 1391
Cdd:TIGR00618  355 IHIRDAHEVATSIREISCQQHTLTQHIHT-LQQQKTTLTQKLQSLCKELDILqreqatidtRTSAFRDLQGQLAHAKKQQ 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1392 ETHLAEMRQEAQSTSRELEVMTAKyegaKVKVLEERQRFQEERQKLT---------AQVEQLEVFQREQTKQVEELSKKL 1462
Cdd:TIGR00618  434 ELQQRYAELCAAAITCTAQCEKLE----KIHLQESAQSLKEREQQLQtkeqihlqeTRKKAVVLARLLELQEEPCPLCGS 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1463 TEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEqlqDL 1542
Cdd:TIGR00618  510 CIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKE---DI 586

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176327 1543 EELQKENKELRSEAERLGR-ELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSRE 1615
Cdd:TIGR00618  587 PNLQNITVRLQDLTEKLSEaEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERV 660
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 119-391 8.96e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 8.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  119 QFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHL-ALLNEKQAASSQEPSELEELRGKNESLTVR 197
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALrEALDELRAELTLLNEEAANLRERLESLERR 832

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  198 LHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREF---ANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELST 274
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELeseLEALLNERASLEEALALLRSELEELSEELRELESKRSE 912

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  275 ALQDKKCLEEKNEILQGKLSQLEDQATRLQESpAPEKGEVLgdalqLDTLKQEAAKLATDNTQLQTRVETLECERGK--- 351
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQER-LSEEYSLT-----LEEAEALENKIEDDEEEARRRLKRLENKIKElgp 986

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1907176327  352 ------QEAQLLAERSRFedekqqLASLIADLQSSVSNLSQAKEEL 391
Cdd:TIGR02168  987 vnlaaiEEYEELKERYDF------LTAQKEDLTEAKETLEEAIEEI 1026
PRK09039 PRK09039
peptidoglycan -binding protein;
476-629 8.99e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.80  E-value: 8.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  476 QEATRQDHA-----QQLAIVAEAreASLRERdtARQQLEtvekekdAKLESLQQQLQAANDARDNAQTSVTQAQQEKAEL 550
Cdd:PRK09039    46 REISGKDSAldrlnSQIAELADL--LSLERQ--GNQDLQ-------DSVANLRASLSAAEAERSRLQALLAELAGAGAAA 114

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327  551 SQKIGELHACIEASHQEQRQVQARVTELEAQLkaeqqktterekvvqekAQLQEQLRALEESLKITKGSLEEEKRRAAD 629
Cdd:PRK09039   115 EGRAGELAQELDSEKQVSARALAQVELLNQQI-----------------AALRRQLAALEAALDASEKRDRESQAKIAD 176
46 PHA02562
endonuclease subunit; Provisional
 1376-1612 9.12e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 9.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1376 AREKYVQELAAVRTDAE------THLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQR 1449
Cdd:PHA02562   151 ARRKLVEDLLDISVLSEmdklnkDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAK 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1450 EQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQ---------AQLSQKEQAAEHYKLQMEK 1520
Cdd:PHA02562   231 TIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEkggvcptctQQISEGPDRITKIKDKLKE 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1521 AKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRD 1600
Cdd:PHA02562   311 LQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDK 390

                          250       260
                   ....*....|....*....|...
gi 1907176327 1601 LGK-----------FQVATDALK 1612
Cdd:PHA02562   391 IVKtkselvkekyhRGIVTDLLK 413
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 758-1028 9.48e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 9.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  758 SEGQpgQQQSQLAQlHASLAKAIQQVQEKEVRA-----------QKLVDDLSALQEKMAATNKEVACLKTLVLKAG--EQ 824
Cdd:NF012221  1538 SESS--QQADAVSK-HAKQDDAAQNALADKERAeadrqrleqekQQQLAAISGSQSQLESTDQNALETNGQAQRDAilEE 1614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  825 QETASLELLKEPPR-AANRASDQLGEQQGRPFSsTHAAVKAMEREAEQM-------GGELERLRAALIKSQGQQQEERGQ 896
Cdd:NF012221  1615 SRAVTKELTTLAQGlDALDSQATYAGESGDQWR-NPFAGGLLDRVQEQLddakkisGKQLADAKQRHVDNQQKVKDAVAK 1693

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  897 QEREVARLTQERGQAQADLAQekaAKAELEMRLQNTLNEQRVefAALQEALAHALTEKegtdqelAKLRGQEAAQRTELK 976
Cdd:NF012221  1694 SEAGVAQGEQNQANAEQDIDD---AKADAEKRKDDALAKQNE--AQQAESDANAAAND-------AQSRGEQDASAAENK 1761

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176327  977 ELQQTLEQLKIQLVKKEKEHPAgGASGEDASGPGTQSETAGKTD-APGPELQA 1028
Cdd:NF012221  1762 ANQAQADAKGAKQDESDKPNRQ-GAAGSGLSGKAYSVEGVAEPGsHINPDSPA 1813
PLN02939 PLN02939
transferase, transferring glycosyl groups
 265-471 1.02e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.12  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  265 QARLE--NELSTALQDKKCLEEKNEILQGKLS---------------------QLEDQATRLQESPAPEKGEVLGDALQL 321
Cdd:PLN02939   149 QARLQalEDLEKILTEKEALQGKINILEMRLSetdariklaaqekihveileeQLEKLRNELLIRGATEGLCVHSLSKEL 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  322 DTLKQEAAKLATDNTQLQTRVETLEcERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQ 401
Cdd:PLN02939   229 DVLKEENMLLKDDIQFLKAELIEVA-ETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVENLQD 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  402 LTAQLTSMTGLNATLQQRDQEL--------ASLKE-QAKKEQAQMLQTMQEQEQAAQG-LRQQVEQLSSSLKLKEQQLEE 471
Cdd:PLN02939   308 LLDRATNQVEKAALVLDQNQDLrdkvdkleASLKEaNVSKFSSYKVELLQQKLKLLEErLQASDHEIHSYIQLYQESIKE 387
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 429-1207 1.09e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.27  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  429 QAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLE---EAAKEQEATRQDHAQQLAIVAEAR------EASLR 499
Cdd:TIGR00606  193 QVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLEssrEIVKSYENELDPLKNRLKEIEHNLskimklDNEIK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  500 ERDTARQQLETVEKEKDAKLESLQQQL-QAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTEL 578
Cdd:TIGR00606  273 ALKSRKKQMEKDNSELELKMEKVFQGTdEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRL 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  579 EAQLKAEQQKTTEREKVVQEKaQLQEQLRALEE----------SLKITKGSLEEEKRRAA-------DALKEQQCRATEM 641
Cdd:TIGR00606  353 QLQADRHQEHIRARDSLIQSL-ATRLELDGFERgpfserqiknFHTLVIERQEDEAKTAAqlcadlqSKERLKQEQADEI 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  642 EAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQ---AETEALRHELAEATASQHRAESECerLIREVES---- 714
Cdd:TIGR00606  432 RDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDrilELDQELRKAERELSKAEKNSLTET--LKKEVKSlqne 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  715 -----RQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVeihsegqpgqqQSQLAQLHASLAKAIQQVQEKEVR 789
Cdd:TIGR00606  510 kadldRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKI-----------KSRHSDELTSLLGYFPNKKQLEDW 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  790 AQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKeppraanrASDQLGEQQGrpfssthaavkamereA 869
Cdd:TIGR00606  579 LHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSS--------YEDKLFDVCG----------------S 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  870 EQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQergqaqadLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAH 949
Cdd:TIGR00606  635 QDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQ--------LTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRL 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  950 ALTEKEGTDQELAKLRgQEAAQRTELKELQQTLEQLKIQLVKKEKEhpaggasgedasgpgtqsetagktdapgpELQAL 1029
Cdd:TIGR00606  707 APDKLKSTESELKKKE-KRRDEMLGLAPGRQSIIDLKEKEIPELRN-----------------------------KLQKV 756

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1030 RAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQdKALETLQGQLEEKARELGHNQAASASA--QRELQALRAKAQDH- 1106
Cdd:TIGR00606  757 NRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDV-TIMERFQMELKDVERKIAQQAAKLQGSdlDRTVQQVNQEKQEKq 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1107 -------SKAEEEWKAQVARGQQEAERKSSLISSLEEEVSI---------LNRQVLEKEGESKELKRLVVAESEKSQKLE 1170
Cdd:TIGR00606  836 heldtvvSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIgtnlqrrqqFEEQLVELSTEVQSLIREIKDAKEQDSPLE 915

                          810       820       830
                   ....*....|....*....|....*....|....*..
gi 1907176327 1171 ERLRLLQVETASNSARAAERSSALREEVQSLREEVEK 1207
Cdd:TIGR00606  916 TFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKN 952
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 424-546 1.09e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.05  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  424 ASLKEQAKKeqaqmlqtMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQlaIVAEAR-EASLRERD 502
Cdd:PRK00409   523 ASLEELERE--------LEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQ--AIKEAKkEADEIIKE 592

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1907176327  503 TARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQE 546
Cdd:PRK00409   593 LRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEE 636
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 941-1575 1.13e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  941 AALQEALAHALTEKEGTDQELAKLRgqeaaQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAgktd 1020
Cdd:TIGR00618  222 QVLEKELKHLREALQQTQQSHAYLT-----QKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKA---- 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1021 APGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAasasaQRELQALR 1100
Cdd:TIGR00618  293 APLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRD-----AHEVATSI 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1101 AKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVET 1180
Cdd:TIGR00618  368 REISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAI 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1181 ASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELgQELKAWQEKFFQKEQALSALQLEHTSTQAL 1260
Cdd:TIGR00618  448 TCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARL-LELQEEPCPLCGSCIHPNPARQDIDNPGPL 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1261 VSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQaaggLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQ 1340
Cdd:TIGR00618  527 TRRMQRGEQTYAQLETSEEDVYHQLTSERKQRAS----LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEK 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1341 LSMLKKAhglLAEENRGLGERAN--LGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEvmtAKYEG 1418
Cdd:TIGR00618  603 LSEAEDM---LACEQHALLRKLQpeQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLP---KELLA 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1419 AKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRL----- 1493
Cdd:TIGR00618  677 SRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQartvl 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1494 ----------------------------------QTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQnqKLQEQL 1539
Cdd:TIGR00618  757 karteahfnnneevtaalqtgaelshlaaeiqffNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQ--EEEQFL 834

                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 1907176327 1540 QDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQ 1575
Cdd:TIGR00618  835 SRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAK 870
PRK12705 PRK12705
hypothetical protein; Provisional
 522-685 1.20e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 43.54  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  522 LQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhaCIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQ 601
Cdd:PRK12705    25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKEL--LLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDN 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  602 LQEQLRALEESLKITKGSLEEEKRRAADALKEQqcrATEMEAESRSLMEQreREQKELEQEKAgrkgleARIQQLEEAHQ 681
Cdd:PRK12705   103 LENQLEEREKALSARELELEELEKQLDNELYRV---AGLTPEQARKLLLK--LLDAELEEEKA------QRVKKIEEEAD 171


                   ....
gi 1907176327  682 AETE 685
Cdd:PRK12705   172 LEAE 175
PRK09039 PRK09039
peptidoglycan -binding protein;
412-582 1.23e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.42  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  412 LNATLQQRDQELASLKEQAkkeqAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkeqqleeAAKEQEatrQDHAQQLAIVA 491
Cdd:PRK09039    44 LSREISGKDSALDRLNSQI----AELADLLSLERQGNQDLQDSVANLRASL---------SAAEAE---RSRLQALLAEL 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  492 EAREASLRERDTarqqletvekEKDAKLESLQQQlqaanDARDNAQTSVTQAQQekAELSQKIGELHACIEASHQEQRQV 571
Cdd:PRK09039   108 AGAGAAAEGRAG----------ELAQELDSEKQV-----SARALAQVELLNQQI--AALRRQLAALEAALDASEKRDRES 170

                          170
                   ....*....|.
gi 1907176327  572 QARVTELEAQL 582
Cdd:PRK09039   171 QAKIADLGRRL 181
PRK11281 PRK11281
mechanosensitive channel MscK;
1283-1587 1.34e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.75  E-value: 1.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1283 KRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLgerA 1362
Cdd:PRK11281    76 DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQL---V 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1363 NLgrqfleveldQAREKYVQelaAVRTDAETHLAEMRQEAQSTSRELEVMTAkyegakvkvleerqrfqEERQKLTAQVE 1442
Cdd:PRK11281   153 SL----------QTQPERAQ---AALYANSQRLQQIRNLLKGGKVGGKALRP-----------------SQRVLLQAEQA 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1443 QLEVfQREQTKQVEELSKKLTEhdqaskvqqqklkAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAaehyklQMEKAk 1522
Cdd:PRK11281   203 LLNA-QNDLQRKSLEGNTQLQD-------------LLQKQRDYLTARIQRLEHQLQLLQEAINSKRLT------LSEKT- 261

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327 1523 thydAKKQQNQKLQEQLQDLEELQKE---NKELRS---EAERLGRELQQAGLKTKE----AEQTCRHLTAQVRSL 1587
Cdd:PRK11281   262 ----VQEAQSQDEAARIQANPLVAQEleiNLQLSQrllKATEKLNTLTQQNLRVKNwldrLTQSERNIKEQISVL 332
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 374-601 1.56e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 1.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  374 IADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQ 453
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  454 QVEQLSSSLKLKEQQ-LEEAAkeqeatrqDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDA 532
Cdd:COG3883     98 SGGSVSYLDVLLGSEsFSDFL--------DRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327  533 RDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQ 601
Cdd:COG3883    170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1422-1597 1.56e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.97  E-value: 1.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1422 KVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQ 1501
Cdd:COG4372      7 KVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELN 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1502 AQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEElqkENKELRSEAERLGRELQQAGLKTKEAEQTCRHLT 1581
Cdd:COG4372     87 EQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQ---QRKQLEAQIAELQSEIAEREEELKELEEQLESLQ 163

                          170
                   ....*....|....*.
gi 1907176327 1582 AQVRSLEAQVAHADQQ 1597
Cdd:COG4372    164 EELAALEQELQALSEA 179
TOPEUc smart00435
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ...
 1517-1600 1.62e-03

DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras


Pssm-ID: 214661 [Multi-domain]  Cd Length: 391  Bit Score: 43.11  E-value: 1.62e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  1517 QMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQ 1596
Cdd:smart00435  278 SMEKLQEKIKALKYQLKRLKKMILLFEMISDLKRKLKSKFERDNEKLDAEVKEKKKEKKKEEKKKKQIERLEERIEKLEV 357


                    ....
gi 1907176327  1597 QLRD 1600
Cdd:smart00435  358 QATD 361
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 310-482 1.64e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 42.80  E-value: 1.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  310 EKGEVLgdaLQLDTLKQEAAKLATDNTQLQTRvetlecergKQEAQLLAERSRFE-------DEKQQLASLIADLQSSVS 382
Cdd:pfam00529   43 KAGDVL---FQLDPTDYQAALDSAEAQLAKAQ---------AQVARLQAELDRLQaleselaISRQDYDGATAQLRAAQA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  383 NLSQAKEELEQA-SQAQGAQLTAQLTSMTGlnATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSS 461
Cdd:pfam00529  111 AVKAAQAQLAQAqIDLARRRVLAPIGGISR--ESLVTAGALVAQAQANLLATVAQLDQIYVQITQSAAENQAEVRSELSG 188

                          170       180
                   ....*....|....*....|.
gi 1907176327  462 LklkEQQLEEAAKEQEATRQD 482
Cdd:pfam00529  189 A---QLQIAEAEAELKLAKLD 206
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 902-1121 1.66e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  902 ARLTQERGQAQADLAQEKAAKAELEMR---LQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKEL 978
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEekaLLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  979 QQTLEQLKIQLVKKEK-EHPAGGASGEDASGPGTQSETAGK-TDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKS 1056
Cdd:COG4942    103 KEELAELLRALYRLGRqPPLALLLSPEDFLDAVRRLQYLKYlAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176327 1057 ERACR-------AEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQ 1121
Cdd:COG4942    183 LEEERaalealkAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGK 254
MreC COG1792
Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome ...
 1523-1584 1.74e-03

Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 441397  Cd Length: 282  Bit Score: 42.56  E-value: 1.74e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907176327 1523 THYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLgRELqqagLKTKEAEQTcRHLTAQV 1584
Cdd:COG1792     68 RSLFNLREENERLKEENAELRAELQRLEELEAENARL-REL----LDLKERLDY-KFVAAEV 123
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 1418-1556 1.97e-03

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 43.11  E-value: 1.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1418 GAKVKVLEERQRFQEERQKLTAQVEQL-EVFQREQTKQvEELSKKLtehdqaskvqQQKLKAFQAQ-------RGESQQE 1489
Cdd:pfam10168  568 LQKEQQLQELQSLEEERKSLSERAEKLaEKYEEIKDKQ-EKLMRRC----------KKVLQRLNSQlpvlsdaEREMKKE 636

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176327 1490 VQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDA---------KKQQNQKLQEQLQDLEELQKENKELRSEA 1556
Cdd:pfam10168  637 LETINEQLKHLANAIKQAKKKMNYQRYQIAKSQSIRKKsslslsekqRKTIKEILKQLGSEIDELIKQVKDINKHV 712
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 568-782 1.98e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 42.53  E-value: 1.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  568 QRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKItkgslEEEKRRAADALKEQQCRATEMEAESRS 647
Cdd:TIGR02794   66 EQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQ-----AEEKQKQAEEAKAKQAAEAKAKAEAEA 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  648 LMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRfEARQQEEA 727
Cdd:TIGR02794  141 ERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAKAEAAKAKAAAEAAA-KAEAEAAA 219

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327  728 RYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQ 782
Cdd:TIGR02794  220 AAAAEAERKADEAELGDIFGLASGSNAEKQGGARGAAAGSEVDKYAAIIQQAIQQ 274
PRK11281 PRK11281
mechanosensitive channel MscK;
520-698 1.99e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.36  E-value: 1.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  520 ESLQQQLQAANDARD------NAQTSVTQAQ---QEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTT 590
Cdd:PRK11281    39 ADVQAQLDALNKQKLleaedkLVQQDLEQTLallDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETL 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  591 EREKVVQEKAQLQEQLRALEE---------SLKITKGSLEEekrRAADALKEQQCRATE--------------------- 640
Cdd:PRK11281   119 STLSLRQLESRLAQTLDQLQNaqndlaeynSQLVSLQTQPE---RAQAALYANSQRLQQirnllkggkvggkalrpsqrv 195

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327  641 -MEAESRSLMEQREREQKELE-----QE--KAGRKGLEARIQQLEEAHQAETEAL---RHELAEATASQ 698
Cdd:PRK11281   196 lLQAEQALLNAQNDLQRKSLEgntqlQDllQKQRDYLTARIQRLEHQLQLLQEAInskRLTLSEKTVQE 264
mukB PRK04863
chromosome partition protein MukB;
206-472 2.00e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 2.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  206 QNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQ---GAFNDLIEEHskasqeWAEKQARLENELSTALQDKKCL 282
Cdd:PRK04863   840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNrllPRLNLLADET------LADRVEEIREQLDEAEEAKRFV 913

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  283 EEKneilQGKLSQLEDQATRLQESP---APEKGEVLGDALQLDTLKQ------------------EAAKLATDNT----Q 337
Cdd:PRK04863   914 QQH----GNALAQLEPIVSVLQSDPeqfEQLKQDYQQAQQTQRDAKQqafaltevvqrrahfsyeDAAEMLAKNSdlneK 989

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  338 LQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEqasqaqgaQLTAQLTSmtGLNATLQ 417
Cdd:PRK04863   990 LRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQ--------DLGVPADS--GAEERAR 1059

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327  418 QRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEA 472
Cdd:PRK04863  1060 ARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNA 1114
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1417-1565 2.06e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 42.31  E-value: 2.06e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  1417 EGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQK----LKAFQAQRGESQQEVQR 1492
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCdpteLDRAKEKLKKLLQEIMI 222

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176327  1493 LQTQLNELQAQLSQKEQAAEhyklqmekakthydAKKQQNQKLQEQLQDLEELQKENKEL-RSEAERLGRELQQ 1565
Cdd:smart00787  223 KVKKLEELEEELQELESKIE--------------DLTNKKSELNTEIAEAEKKLEQCRGFtFKEIEKLKEQLKL 282
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
320-625 2.11e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.58  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  320 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQaQG 399
Cdd:COG4372     32 QLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE-EA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  400 AQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLklkeQQLEEAAKEQEAT 479
Cdd:COG4372    111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL----QALSEAEAEQALD 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  480 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHA 559
Cdd:COG4372    187 ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELA 266

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176327  560 CIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKR 625
Cdd:COG4372    267 ILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELAL 332
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1424-1597 2.11e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1424 LEERQRFQEERQKLTAQVEQLevfqREQTKQVEELSKKLTEHDQASKVQQQKLKA--FQAQRGESQQEVQRLQTQLNELQ 1501
Cdd:COG4717     70 LKELKELEEELKEAEEKEEEY----AELQEELEELEEELEELEAELEELREELEKleKLLQLLPLYQELEALEAELAELP 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1502 AQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKEN-KELRSEAERLGRELQQAGLKTKEAEQTCRHL 1580
Cdd:COG4717    146 ERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELEEL 225

                          170
                   ....*....|....*..
gi 1907176327 1581 TAQVRSLEAQVAHADQQ 1597
Cdd:COG4717    226 EEELEQLENELEAAALE 242
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 577-725 2.48e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  577 ELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQRERE- 655
Cdd:COG1579     14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEa 93

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176327  656 -QKELEQEKAGRKGLEARIQQLE---EAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQE 725
Cdd:COG1579     94 lQKEIESLKRRISDLEDEILELMeriEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREE 167
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 912-1559 2.58e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.90  E-value: 2.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  912 QADLAQEKAAKAELE------MRLQNTLNEQRVEFAALQEALAHALTEKEGTDQEL-AKLRGQEAAQRTELKELQQTLEQ 984
Cdd:pfam12128  247 QQEFNTLESAELRLShlhfgyKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKrDELNGELSAADAAVAKDRSELEA 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  985 LKIQLVKKEKEHpAGGASGEDASGPGTQSET-------AGKTDAPGPELQALRAEISKLeqqCQQQQQQVEGLTHSLKSE 1057
Cdd:pfam12128  327 LEDQHGAFLDAD-IETAAADQEQLPSWQSELenleerlKALTGKHQDVTAKYNRRRSKI---KEQNNRDIAGIKDKLAKI 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1058 RACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAK----AQDHSKAEEEWKAQVARGQQEAERKSSLISS 1133
Cdd:pfam12128  403 REARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGelklRLNQATATPELLLQLENFDERIERAREEQEA 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1134 LEEEVSILNRQVLEKEGESKELKRlvvAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKqrVVSe 1213
Cdd:pfam12128  483 ANAEVERLQSELRQARKRRDQASE---ALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGK--VIS- 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1214 nsrQELASQAERAEELGQELKAWQEKFFQKEQALSALQLE--HTSTQALVSELLPAKhlcqQLQAEQAAAEKRFREELEQ 1291
Cdd:pfam12128  557 ---PELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPewAASEEELRERLDKAE----EALQSAREKQAAAEEQLVQ 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1292 SKQAAGGLQAELMRAQREL-----------GELGSLRQKIVEQERAAQQLRAEK-ASYAEQLSMLKKAHGLLAEENRG-- 1357
Cdd:pfam12128  630 ANGELEKASREETFARTALknarldlrrlfDEKQSEKDKKNKALAERKDSANERlNSLEAQLKQLDKKHQAWLEEQKEqk 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1358 --LGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEaqsTSRELevmtakyegAKVKVLEER-QRFQEER 1434
Cdd:pfam12128  710 reARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETW---YKRDL---------ASLGVDPDViAKLKREI 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1435 QKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQAskvqqqklkaFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHY 1514
Cdd:pfam12128  778 RTLERKIERIAVRRQEVLRYFDWYQETWLQRRPR----------LATQLSNIERAISELQQQLARLIADTKLRRAKLEME 847

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1907176327 1515 KLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERL 1559
Cdd:pfam12128  848 RKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERL 892
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 517-648 2.58e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 43.02  E-value: 2.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  517 AKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELhacieashqeqrqvQARVTELEAQLKAEQQKTTEREKvv 596
Cdd:PRK11448   149 QEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAEL--------------EEKQQELEAQLEQLQEKAAETSQ-- 212

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907176327  597 QEKAQLQEQLRALEESLKITkgslEEEKRRAADalkeQQCRATEMEAESRSL 648
Cdd:PRK11448   213 ERKQKRKEITDQAAKRLELS----EEETRILID----QQLRKAGWEADSKTL 256
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 368-529 2.62e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 2.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  368 QQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQA 447
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  448 AqgLRQQVEqlssSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQ 527
Cdd:COG1579     93 A--LQKEIE----SLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAERE 166


                   ..
gi 1907176327  528 AA 529
Cdd:COG1579    167 EL 168
PRK12705 PRK12705
hypothetical protein; Provisional
 1375-1532 2.70e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 42.77  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1375 QAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELevMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqrEQTKQ 1454
Cdd:PRK12705    26 KKRQRLAKEAERILQEAQKEAEEKLEAALLEAKEL--LLRERNQQRQEARREREELQREEERLVQKEEQLD----ARAEK 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1455 VEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRL-QTQLNELQAQLSQ---KEQAAEHYKLQMEKAKTHYDAKKQ 1530
Cdd:PRK12705   100 LDNLENQLEEREKALSARELELEELEKQLDNELYRVAGLtPEQARKLLLKLLDaelEEEKAQRVKKIEEEADLEAERKAQ 179


                   ..
gi 1907176327 1531 QN 1532
Cdd:PRK12705   180 NI 181
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 477-669 3.04e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 42.30  E-value: 3.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  477 EATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAK---LESLQQQLQAANDARDNAQTSVTQAQQEKAELSQK 553
Cdd:pfam05262  184 EALREDNEKGVNFRRDMTDLKERESQEDAKRAQQLKEELDKKqidADKAQQKADFAQDNADKQRDEVRQKQQEAKNLPKP 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  554 igelhacieashqeqrqvqARVTEleaqlKAEQQKTTEREKVVQEKAQlQEQLRALEESLKitkgsleeEKRRAADALKe 633
Cdd:pfam05262  264 -------------------ADTSS-----PKEDKQVAENQKREIEKAQ-IEIKKNDEEALK--------AKDHKAFDLK- 309

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1907176327  634 QQCRATEMEAESRSLMEQRERE------QKELEQEKAGRKGL 669
Cdd:pfam05262  310 QESKASEKEAEDKELEAQKKREpvaedlQKTKPQVEAQPTSL 351
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 518-696 3.05e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 3.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  518 KLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKtterekvvQ 597
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ--------L 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  598 EKAQLQEQLRALEESLKitkgSLEEEKRRAADALKEqqcratemeaesrsLMEQREREQKELEQEKAGRKGLEARIQQLE 677
Cdd:COG1579     83 GNVRNNKEYEALQKEIE----SLKRRISDLEDEILE--------------LMERIEELEEELAELEAELAELEAELEEKK 144

                          170
                   ....*....|....*....
gi 1907176327  678 EAHQAETEALRHELAEATA 696
Cdd:COG1579    145 AELDEELAELEAELEELEA 163
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1315-1522 3.08e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 3.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1315 SLRQKIVEQERAAQQLRAEKASYAEQL-------SMLKKAHGLLAEENRGLGERANLGRqfLEVELDQAREKYvQELAAV 1387
Cdd:COG3206    165 NLELRREEARKALEFLEEQLPELRKELeeaeaalEEFRQKNGLVDLSEEAKLLLQQLSE--LESQLAEARAEL-AEAEAR 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1388 RTDAETHLAEMRQEAQ--STSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEH 1465
Cdd:COG3206    242 LAALRAQLGSGPDALPelLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAE 321

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176327 1466 DQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAK 1522
Cdd:COG3206    322 LEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 540-679 3.09e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.51  E-value: 3.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  540 VTQAQQEKAELSQKIGELhacIEASHQEQRQVQARVTELEaQLKAEQQKTteREKVVQEKAQLQEQLRALeeslkitkgs 619
Cdd:PRK00409   504 IEEAKKLIGEDKEKLNEL---IASLEELERELEQKAEEAE-ALLKEAEKL--KEELEEKKEKLQEEEDKL---------- 567

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  620 LEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAgRKGLEARIQQLEEA 679
Cdd:PRK00409   568 LEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYASVKAHELIEA-RKRLNKANEKKEKK 626
PRK06975 PRK06975
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
 1474-1662 3.18e-03

bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed


Pssm-ID: 235899 [Multi-domain]  Cd Length: 656  Bit Score: 42.40  E-value: 3.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1474 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQaaehyKLQMEKAKThydakkqqnQKLQEQLQDLeeLQKENKELR 1553
Cdd:PRK06975   357 QRQQANDAQTAELRVKTEQAQASVHQLDSQFAQLDG-----KLADAQSAQ---------QALEQQYQDL--SRNRDDWMI 420

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1554 SEAERLgreLQQAGLKTkeaeqtcrHLTAQVRSLEAQVAHADQQLRDLGKFQVAT---------DALKSrepqvKPQLDL 1624
Cdd:PRK06975   421 AEVEQM---LSSASQQL--------QLTGNVQLALIALQNADARLATSDSPQAVAvrkaiaqdiERLKA-----APSADL 484

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1625 S------------IDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASP 1662
Cdd:PRK06975   485 TglaiklddaiakIDALPLSGEALPPHATMAAAPAAAAAAAAAAAAAGEP 534
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1074-1327 3.24e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1074 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1153
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1154 ELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRvvseNSRQELASQAERAEELGQEL 1233
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELR----ADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1234 KAWQEKFFQKEQALSALQLEHTSTQAlvsellpakhlcqqlqaeqaaaekrfreELEQSKQAAGGLQAELMRAQREL-GE 1312
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLA----------------------------RLEKELAELAAELAELQQEAEELeAL 228

                          250
                   ....*....|....*
gi 1907176327 1313 LGSLRQKIVEQERAA 1327
Cdd:COG4942    229 IARLEAEAAAAAERT 243
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
837-1252 3.31e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  837 PRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALikSQGQQQEERGQQEREVARLTQERGQAQADLA 916
Cdd:COG4717     65 KPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAEL--EELREELEKLEKLLQLLPLYQELEALEAELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  917 QEKAAKAELEMR------LQNTLNEQRVEFAALQEALAHALTEK--------EGTDQELAKLRGQEAAQRTELKELQQTL 982
Cdd:COG4717    143 ELPERLEELEERleelreLEEELEELEAELAELQEELEELLEQLslateeelQDLAEELEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  983 EQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRA 1062
Cdd:COG4717    223 EELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGK 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1063 EQDK-----ALETLQGQ-LEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEE 1136
Cdd:COG4717    303 EAEElqalpALEELEEEeLEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVE 382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1137 EVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETAsnsARAAERSSALREEVQSLREEVEK--QRVVSEN 1214
Cdd:COG4717    383 DEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE---EELEEELEELEEELEELEEELEElrEELAELE 459

                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 1907176327 1215 SRQELASQAERAEELGQELKAWQEKFFQKEQALSALQL 1252
Cdd:COG4717    460 AELEQLEEDGELAELLQELEELKAELRELAEEWAALKL 497
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1219-1484 3.32e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1219 LASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqqlqaeqaaaekrfREELEQSKQAAGG 1298
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL---------------------ERRIAALARRIRA 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1299 LQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERanlgRQFLEVELDQARE 1378
Cdd:COG4942     74 LEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVR----RLQYLKYLAPARR 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1379 KYVQELAAVRTDaethLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEEL 1458
Cdd:COG4942    150 EQAEELRADLAE----LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL 225

                          250       260
                   ....*....|....*....|....*...
gi 1907176327 1459 SKKLTEHDQASKVQQQKLKA--FQAQRG 1484
Cdd:COG4942    226 EALIARLEAEAAAAAERTPAagFAALKG 253
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1458-1606 3.36e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 3.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1458 LSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQE 1537
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907176327 1538 QL----QDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQV 1606
Cdd:COG4372    109 EAeelqEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEA 181
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 175-399 3.41e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  175 AASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEH 254
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  255 SKASQEWAEKQARLENELSTAL--------------QDKKCLEEKNEILQGKLSQLEDQATRLQEspapEKGEVLGDALQ 320
Cdd:COG4942     93 AELRAELEAQKEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRA----DLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327  321 LDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQG 399
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
GBP_C pfam02841
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...
 577-725 3.61e-03

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.


Pssm-ID: 460721 [Multi-domain]  Cd Length: 297  Bit Score: 41.50  E-value: 3.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  577 ELEAQLKAEQQKTTEREKVVQEKAQLQEqlrALEESLKITKGSLEEEKRraadALKEQQCRATEMEAESRSLMEQREREQ 656
Cdd:pfam02841  159 KLEAKYNQVPRKGVKAEEVLQEFLQSKE---AVEEAILQTDQALTAKEK----AIEAERAKAEAAEAEQELLREKQKEEE 231

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327  657 KELEQEKagrKGLEARIQQLEEAHQAETEALRHELaEATASQHRAESecERLIRevESRQKRFEARQQE 725
Cdd:pfam02841  232 QMMEAQE---RSYQEHVKQLIEKMEAEREQLLAEQ-ERMLEHKLQEQ--EELLK--EGFKTEAESLQKE 292
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
484-611 3.91e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.57  E-value: 3.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  484 AQQLAIVAEAREASLRERDTARQQLETVEkekdAKLESLQQQLQAANDARDNAQT-----SVTQAQQEKAElsqkigelh 558
Cdd:COG1566     88 AEAQLAAAEAQLARLEAELGAEAEIAAAE----AQLAAAQAQLDLAQRELERYQAlykkgAVSQQELDEAR--------- 154

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176327  559 acieashQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEE 611
Cdd:COG1566    155 -------AALDAAQAQLEAAQAQLAQAQAGLREEEELAAAQAQVAQAEAALAQ 200
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1025-1249 3.95e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 3.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1025 ELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1104
Cdd:COG4942     28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1105 DH----SKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVET 1180
Cdd:COG4942    108 ELlralYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER 187

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327 1181 ASNSARAAERSSALREEVQSLREEvekqrvvsensRQELASQAERAEELGQELKAWQEKFFQKEQALSA 1249
Cdd:COG4942    188 AALEALKAERQKLLARLEKELAEL-----------AAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
mukB PRK04863
chromosome partition protein MukB;
1026-1601 4.30e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 4.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1026 LQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKaLETLQGQLEEKARELGHNQAASASAQRELQALRAKAQD 1105
Cdd:PRK04863   309 LVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEK-IERYQADLEELEERLEEQNEVVEEADEQQEENEARAEA 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1106 HSKAEEEWKAQVARGQQ---EAERKSS----LISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQK---LEERLRL 1175
Cdd:PRK04863   388 AEEEVDELKSQLADYQQaldVQQTRAIqyqqAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEEllsLEQKLSV 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1176 L-----QVETASNSARAA----ERSSALREEVQSLREeVEKQRVVSENS----------RQELASQAeRAEELGQELKAW 1236
Cdd:PRK04863   468 AqaahsQFEQAYQLVRKIagevSRSEAWDVARELLRR-LREQRHLAEQLqqlrmrlselEQRLRQQQ-RAERLLAEFCKR 545

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1237 QEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGE---- 1312
Cdd:PRK04863   546 LGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEefed 625

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1313 ---LGSLRQKIVEQERAAQQ----LRAEKASYAEQLSMLKKAHGLLAEENRGLGERAN---LGRQFLEVELDQARE---K 1379
Cdd:PRK04863   626 sqdVTEYMQQLLERERELTVerdeLAARKQALDEEIERLSQPGGSEDPRLNALAERFGgvlLSEIYDDVSLEDAPYfsaL 705

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1380 YVQELAAV----RTDAETHLAEMR-------------QEAQSTSRELEVMtakyEGAKVKVLEERQ----RFQEE----R 1434
Cdd:PRK04863   706 YGPARHAIvvpdLSDAAEQLAGLEdcpedlyliegdpDSFDDSVFSVEEL----EKAVVVKIADRQwrysRFPEVplfgR 781

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1435 QKLTAQVEQLevfqREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQ------RGESQQEVQRLQTQLNELQAQLSQKE 1508
Cdd:PRK04863   782 AAREKRIEQL----RAEREELAERYATLSFDVQKLQRLHQAFSRFIGShlavafEADPEAELRQLNRRRVELERALADHE 857

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1509 QAAEHYKLQMEKAKTHYdakkQQNQKLQEQ--LQDLEELQKENKELRSE---AERLGRELQQAGLKTKEAEQ---TCRHL 1580
Cdd:PRK04863   858 SQEQQQRSQLEQAKEGL----SALNRLLPRlnLLADETLADRVEEIREQldeAEEAKRFVQQHGNALAQLEPivsVLQSD 933

                          650       660
                   ....*....|....*....|.
gi 1907176327 1581 TAQVRSLEAQVAHADQQLRDL 1601
Cdd:PRK04863   934 PEQFEQLKQDYQQAQQTQRDA 954
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 931-1623 4.66e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 4.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  931 NTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTE-----------LKELQQTLEQLKIQLVKKEKEHPAG 999
Cdd:pfam01576  218 TDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNalkkireleaqISELQEDLESERAARNKAEKQRRDL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1000 GASGEDASG--------PGTQSETAGKTDAPGPELQALRAEISK-----LEQQCQQQQQQVEGLTHSLKSERACRAEQDK 1066
Cdd:pfam01576  298 GEELEALKTeledtldtTAAQQELRSKREQEVTELKKALEEETRsheaqLQEMRQKHTQALEELTEQLEQAKRNKANLEK 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1067 ALETLQGQLEEKARELGHNQAASASAQR-------ELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVS 1139
Cdd:pfam01576  378 AKQALESENAELQAELRTLQQAKQDSEHkrkklegQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNI 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1140 ILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSAlREEVQSLREEVEKQRVVSENSRQEL 1219
Cdd:pfam01576  458 KLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEA-KRNVERQLSTLQAQLSDMKKKLEED 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1220 ASQAERAEE----LGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQA 1295
Cdd:pfam01576  537 AGTLEALEEgkkrLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAI 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1296 AGGLQAELMRAQRELGE-----------LGSLRQKIVEQERAAQQLRAEK----------ASYAEQLSMLKKAHGLLAEE 1354
Cdd:pfam01576  617 SARYAEERDRAEAEAREketralslaraLEEALEAKEELERTNKQLRAEMedlvsskddvGKNVHELERSKRALEQQVEE 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1355 NRGLGER-------ANLGRQFLEVELDQAREKYVQELAAVRTDAEthlaEMRQEAQSTSRELEVMTAKYEGAKVKVLEER 1427
Cdd:pfam01576  697 MKTQLEEledelqaTEDAKLRLEVNMQALKAQFERDLQARDEQGE----EKRRQLVKQVRELEAELEDERKQRAQAVAAK 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1428 QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQK 1507
Cdd:pfam01576  773 KKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAAS 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1508 EQA-----AEHYKLQMEKAKTHYDAKKQQNQK--LQEQLQDLEE-----------LQKENKELRSEAERLGRELQQAGLK 1569
Cdd:pfam01576  853 ERArrqaqQERDELADEIASGASGKSALQDEKrrLEARIAQLEEeleeeqsntelLNDRLRKSTLQVEQLTTELAAERST 932

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907176327 1570 TKEAEQTCRHLTAQVRSLEAQVAHADQQLRdlGKFQVATDALKSREPQVKPQLD 1623
Cdd:pfam01576  933 SQKSESARQQLERQNKELKAKLQEMEGTVK--SKFKSSIAALEAKIAQLEEQLE 984
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 364-472 4.67e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 42.25  E-value: 4.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  364 EDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKeqaqmlqtmQE 443
Cdd:PRK11448   141 ENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAE---------TS 211

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1907176327  444 QEQAAQgLRQQVEQLSSSLKLKE--------QQLEEA 472
Cdd:PRK11448   212 QERKQK-RKEITDQAAKRLELSEeetrilidQQLRKA 247
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
351-688 5.50e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 5.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  351 KQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQA 430
Cdd:COG4372      3 RLGEKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEEL 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  431 KKEQAQMLQTMQEQEQAaqglRQQVEQLSSSLKLKEQQLEEAAKEQEAtRQDHAQQLAIVAEAREASLRERDTARQQLET 510
Cdd:COG4372     83 EELNEQLQAAQAELAQA----QEELESLQEEAEELQEELEELQKERQD-LEQQRKQLEAQIAELQSEIAEREEELKELEE 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  511 VEKEKDAKLESLQQQLQAANDARDNAQ--TSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQK 588
Cdd:COG4372    158 QLESLQEELAALEQELQALSEAEAEQAldELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSA 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  589 TTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKG 668
Cdd:COG4372    238 LLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDAL 317

                          330       340
                   ....*....|....*....|
gi 1907176327  669 LEARIQQLEEAHQAETEALR 688
Cdd:COG4372    318 LAALLELAKKLELALAILLA 337
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 381-488 5.68e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 41.25  E-value: 5.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  381 VSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASlkeqAKKEQAQMLQTM-QEQEQAAQGLRQQVEQLS 459
Cdd:TIGR04320  249 IPNPPNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAA----AQAALATAQKELaNAQAQALQTAQNNLATAQ 324

                           90       100
                   ....*....|....*....|....*....
gi 1907176327  460 SSLKLKEQQLEEAAKEQEATRQDHAQQLA 488
Cdd:TIGR04320  325 AALANAEARLAKAKEALANLNADLAKKQA 353
mukB PRK04863
chromosome partition protein MukB;
1285-1590 6.02e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.87  E-value: 6.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1285 FREELEQSKQAAGGLQAELMRAQRELGELgSLRQKIVEQE----RAAQQLRAEKASYAEQLSMLKKAHGLL---AEENRG 1357
Cdd:PRK04863   291 LRRELYTSRRQLAAEQYRLVEMARELAEL-NEAESDLEQDyqaaSDHLNLVQTALRQQEKIERYQADLEELeerLEEQNE 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1358 LGERANLGRQFLEVELDQAREKYVQ---ELAAVRT--DAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQE 1432
Cdd:PRK04863   370 VVEEADEQQEENEARAEAAEEEVDElksQLADYQQalDVQQTRAIQYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQA 449

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1433 ERQKLTAQVEQLEvfQR--------EQTKQVEELSKKL---TEHDQASKVQQQKLKAFQAQRGESQQeVQRLQTQLNELQ 1501
Cdd:PRK04863   450 KEQEATEELLSLE--QKlsvaqaahSQFEQAYQLVRKIageVSRSEAWDVARELLRRLREQRHLAEQ-LQQLRMRLSELE 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1502 aQLSQKEQAAEHyklqmekakthydAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLT 1581
Cdd:PRK04863   527 -QRLRQQQRAER-------------LLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQ 592


                   ....*....
gi 1907176327 1582 AQVRSLEAQ 1590
Cdd:PRK04863   593 ARIQRLAAR 601
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 408-986 6.08e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 6.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  408 SMTGLNATLQQRDQELASLKEQAKKEQaqmlqtmQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQL 487
Cdd:pfam15921  111 SVIDLQTKLQEMQMERDAMADIRRRES-------QSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHE 183

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  488 AIVAEAR-------EAS---LRERDTAR---------------QQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQ 542
Cdd:pfam15921  184 GVLQEIRsilvdfeEASgkkIYEHDSMStmhfrslgsaiskilRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQ 263

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  543 AQQEKAElsQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQqktterEKVVQEKAQLQEQLRALEESLKITKGSLEE 622
Cdd:pfam15921  264 QHQDRIE--QLISEHEVEITGLTEKASSARSQANSIQSQLEIIQ------EQARNQNSMYMRQLSDLESTVSQLRSELRE 335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  623 EKRRAADALKEQQCRATEMEAEsrsLMEQRErEQKELEQEKAgrkGLEARIQQ-LEEAHQAETE-ALRHELAEATASQHR 700
Cdd:pfam15921  336 AKRMYEDKIEELEKQLVLANSE---LTEART-ERDQFSQESG---NLDDQLQKlLADLHKREKElSLEKEQNKRLWDRDT 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  701 AESecerliREVESRQKRFEARQQEEARYGAMfqeqLMALKGEKTGQeVQEEAVEIHSEGQPGQQQSQL-AQLHAS---L 776
Cdd:pfam15921  409 GNS------ITIDHLRRELDDRNMEVQRLEAL----LKAMKSECQGQ-MERQMAAIQGKNESLEKVSSLtAQLESTkemL 477

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  777 AKAIQQVQEKEV---RAQKLVDDLSA-LQEK---MAATNKEVACLKTLV-LKAGE--------------QQETASLEL-- 832
Cdd:pfam15921  478 RKVVEELTAKKMtleSSERTVSDLTAsLQEKeraIEATNAEITKLRSRVdLKLQElqhlknegdhlrnvQTECEALKLqm 557

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  833 -----LKEPPRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRA------ALIKSQGQQQEERGQQEREV 901
Cdd:pfam15921  558 aekdkVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKIlkdkkdAKIRELEARVSDLELEKVKL 637

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  902 ARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQelaKLRGQEAAQRTELKELQQT 981
Cdd:pfam15921  638 VNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN---KLKMQLKSAQSELEQTRNT 714


                   ....*
gi 1907176327  982 LEQLK 986
Cdd:pfam15921  715 LKSME 719
PRK12704 PRK12704
phosphodiesterase; Provisional
 1434-1575 6.39e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 6.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1434 RQKLTAQVEQLEVFQREQTKQVEELSK-KLTEhdqaSKVQQQKLKA-FQAQRGESQQEVQRLQTQLNELQAQLSQKEQAA 1511
Cdd:PRK12704    30 EAKIKEAEEEAKRILEEAKKEAEAIKKeALLE----AKEEIHKLRNeFEKELRERRNELQKLEKRLLQKEENLDRKLELL 105

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176327 1512 EHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEelQKENKELrseaERLgrelqqAGLKTKEAEQ 1575
Cdd:PRK12704   106 EKREEELEKKEKELEQKQQELEKKEEELEELI--EEQLQEL----ERI------SGLTAEEAKE 157
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1169-1512 6.78e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.42  E-value: 6.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1169 LEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSEnSRQELASQAERAEELGQELKAWQEKFFQKEQALS 1248
Cdd:pfam07888   40 LQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAE-LKEELRQSREKHEELEEKYKELSASSEELSEEKD 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1249 ALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAG-------GLQAELMRAQREL----GELGSLR 1317
Cdd:pfam07888  119 ALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKeeeaerkQLQAKLQQTEEELrslsKEFQELR 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1318 QKIVEQERAAQQLRAEKASYAEQLSMLKK---AHGLLAEENRGLGERANLGRQFLEveldqAREKYVQELAAVRTDAETH 1394
Cdd:pfam07888  199 NSLAQRDTQVLQLQDTITTLTQKLTTAHRkeaENEALLEELRSLQERLNASERKVE-----GLGEELSSMAAQRDRTQAE 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1395 LAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQ-------EERQKLTAQVEQLEVFQREQTKQVEELSKKLTEHDQ 1467
Cdd:pfam07888  274 LHQARLQAAQLTLQLADASLALREGRARWAQERETLQqsaeadkDRIEKLSAELQRLEERLQEERMEREKLEVELGREKD 353

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1907176327 1468 ASKVQ----QQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAE 1512
Cdd:pfam07888  354 CNRVQlsesRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
PTZ00491 PTZ00491
major vault protein; Provisional
 509-664 6.83e-03

major vault protein; Provisional


Pssm-ID: 240439 [Multi-domain]  Cd Length: 850  Bit Score: 41.54  E-value: 6.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  509 ETVEKEKDAKLESLQQQLQAANDARDNAQTSvtQAQQEKAELSQkigelhaciEASHQEQRQVqarvteLEAQLKAEQQK 588
Cdd:PTZ00491   636 QSVEPVDERTRDSLQKSVQLAIEITTKSQEA--AARHQAELLEQ---------EARGRLERQK------MHDKAKAEEQR 698

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907176327  589 TTEREkVVQEKAQLQEQLRALEESLKITKGSLEEEkrRAADALKEQQCRATEMEAESRSLMEQREREQkELEQEKA 664
Cdd:PTZ00491   699 TKLLE-LQAESAAVESSGQSRAEALAEAEARLIEA--EAEVEQAELRAKALRIEAEAELEKLRKRQEL-ELEYEQA 770
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1372-1575 7.13e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 7.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1372 ELDQAREKYVQELAAVRTDAETHLAEMRQE-----AQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEV 1446
Cdd:pfam17380  320 EAEKARQAEMDRQAAIYAEQERMAMERERElerirQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELE 399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1447 FQREQTKQVEELSKKLTEHDQAS---KVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQ-----LSQKEQAAEHYKLQM 1518
Cdd:pfam17380  400 AARKVKILEEERQRKIQQQKVEMeqiRAEQEEARQREVRRLEEERAREMERVRLEEQERQqqverLRQQEEERKRKKLEL 479

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907176327 1519 EKAKTHYDAKKQQNQKLQEqlQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQ 1575
Cdd:pfam17380  480 EKEKRDRKRAEEQRRKILE--KELEERKQAMIEEERKRKLLEKEMEERQKAIYEEER 534
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1093-1592 7.14e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 7.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1093 QRELQALRAKAQDHSKAEEEWKAQVARGQQEAER----KSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKS-Q 1167
Cdd:pfam15921  123 QMERDAMADIRRRESQSQEDLRNQLQNTVHELEAakclKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASgK 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1168 KLEERLRLLQVETASNSARAAERSSALREEVQSLR-------EEVEKQRVVSENSRQELASQ-AERAEELGQE----LKA 1235
Cdd:pfam15921  203 KIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKgrifpveDQLEALKSESQNKIELLLQQhQDRIEQLISEheveITG 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1236 WQEKFFQKEQALSALQ--LEHTSTQALVSELLPAKHLcqqlqAEQAAAEKRFREELEQSKQAAGG----LQAELMRAQRE 1309
Cdd:pfam15921  283 LTEKASSARSQANSIQsqLEIIQEQARNQNSMYMRQL-----SDLESTVSQLRSELREAKRMYEDkieeLEKQLVLANSE 357

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1310 LGELGSLRQKIVEQ----ERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGlgerANLGRQFLEVELDQaREKYVQELA 1385
Cdd:pfam15921  358 LTEARTERDQFSQEsgnlDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTG----NSITIDHLRRELDD-RNMEVQRLE 432

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1386 AVrtdaethLAEMRQEAQStsrELEVMTAKYEGAkvkvleerqrfQEERQKLTAQVEQLEVFQREQTKQVEELS-KKLTE 1464
Cdd:pfam15921  433 AL-------LKAMKSECQG---QMERQMAAIQGK-----------NESLEKVSSLTAQLESTKEMLRKVVEELTaKKMTL 491

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1465 HDQASKVQ------QQKLKAFQAQRGESQQEVQRLQTQLNELQaQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQ 1538
Cdd:pfam15921  492 ESSERTVSdltaslQEKERAIEATNAEITKLRSRVDLKLQELQ-HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQ 570

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176327 1539 LQDLEELQKENKE----LRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVA 1592
Cdd:pfam15921  571 IENMTQLVGQHGRtagaMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVS 628
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1474-1600 7.19e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 7.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1474 QKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQ------DLEELQK 1547
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvrnnkEYEALQK 96

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907176327 1548 ENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRD 1600
Cdd:COG1579     97 EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDE 149
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 524-697 7.52e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 40.95  E-value: 7.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  524 QQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQE--QRQVQARVTELEAQLKAEQQKTTEREKVVQE--- 598
Cdd:PRK09510    66 RQQQQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKErlAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAaaa 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  599 KAQLQEQLRALEESLKITKgslEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEE 678
Cdd:PRK09510   146 KAKAEAEAKRAAAAAKKAA---AEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKKAAAE 222

                          170
                   ....*....|....*....
gi 1907176327  679 AHQAETEALRHELAEATAS 697
Cdd:PRK09510   223 AKAAAAKAAAEAKAAAEKA 241
mukB PRK04863
chromosome partition protein MukB;
1352-1566 7.75e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.48  E-value: 7.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1352 AEENRGLGERANLGRQflevELDQAREKyvqelaavRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKvkvlEERQRFQ 1431
Cdd:PRK04863   278 ANERRVHLEEALELRR----ELYTSRRQ--------LAAEQYRLVEMARELAELNEAESDLEQDYQAAS----DHLNLVQ 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1432 EERqkltAQVEQLEVFQREqtkqVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAA 1511
Cdd:PRK04863   342 TAL----RQQEKIERYQAD----LEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRA 413

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327 1512 ehykLQMEKAKTHYDAKKQQNQK---LQEQLQD-LEELQKENKELRSEAERLGRELQQA 1566
Cdd:PRK04863   414 ----IQYQQAVQALERAKQLCGLpdlTADNAEDwLEEFQAKEQEATEELLSLEQKLSVA 468
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 320-543 8.10e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 8.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  320 QLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQg 399
Cdd:COG3883     38 ELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYLDVLLGSESFSD- 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  400 aqLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAT 479
Cdd:COG3883    117 --FLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAA 194

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176327  480 RQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQA 543
Cdd:COG3883    195 EAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAA 258
PRK09039 PRK09039
peptidoglycan -binding protein;
1434-1566 8.33e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 40.72  E-value: 8.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1434 RQKLTAQVEQLEvfqrEQTKQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQ------- 1506
Cdd:PRK09039    45 SREISGKDSALD----RLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAaegrage 120

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907176327 1507 KEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEEL----QKENKELRSEAERLGRELQQA 1566
Cdd:PRK09039   121 LAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAAldasEKRDRESQAKIADLGRRLNVA 184
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 920-1172 8.74e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 8.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  920 AAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEhpag 999
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE---- 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1000 gasgedasgpgtqsetagkTDAPGPELQALRAEISKL--EQQCQQQQQQVEGLTHSLKSERACRAEQdkALETLQGQLEE 1077
Cdd:COG4942     92 -------------------IAELRAELEAQKEELAELlrALYRLGRQPPLALLLSPEDFLDAVRRLQ--YLKYLAPARRE 150

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1078 KARELGHNQAASASAQRELQALRAKAQdhsKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKR 1157
Cdd:COG4942    151 QAEELRADLAELAALRAELEAERAELE---ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227

                          250
                   ....*....|....*
gi 1907176327 1158 LVVAESEKSQKLEER 1172
Cdd:COG4942    228 LIARLEAEAAAAAER 242
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
504-756 8.93e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 8.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  504 ARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLK 583
Cdd:COG4372     11 ARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQ 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  584 AEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEK 663
Cdd:COG4372     91 AAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  664 AGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGE 743
Cdd:COG4372    171 QELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEE 250

                          250
                   ....*....|...
gi 1907176327  744 KTGQEVQEEAVEI 756
Cdd:COG4372    251 LLEEVILKEIEEL 263
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 474-679 8.94e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 40.56  E-value: 8.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  474 KEQEATRQDHAQQLAIVAEAREASLRERDTARQQ-LETVEKEKDAKLESLQQQLQAANDARdnaqtsvtQAQQEKAELSQ 552
Cdd:PRK09510    68 QQQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQErLKQLEKERLAAQEQKKQAEEAAKQAA--------LKQKQAEEAAA 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  553 KIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKitKGSLEEEKRRAADALK 632
Cdd:PRK09510   140 KAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKK--KAEAEAKKKAAAEAKK 217

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1907176327  633 EQqcratemEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEA 679
Cdd:PRK09510   218 KA-------AAEAKAAAAKAAAEAKAAAEKAAAAKAAEKAAAAKAAA 257
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 492-731 8.98e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 8.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  492 EAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQV 571
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  572 QARVTELEAQLKAEQ-----QKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESR 646
Cdd:COG3883     99 GGSVSYLDVLLGSESfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQA 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  647 SLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEE 726
Cdd:COG3883    179 EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAA 258


                   ....*
gi 1907176327  727 ARYGA 731
Cdd:COG3883    259 AGSAG 263
PRK11281 PRK11281
mechanosensitive channel MscK;
942-1251 9.41e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.05  E-value: 9.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  942 ALQEALAHALTEKEGTDQ--ELAKLRGQEAAQRTELKELQQTLEQL-KIQLVKKEKEHPAGGASGEDASgpgTQSETAGK 1018
Cdd:PRK11281    27 ARAASNGDLPTEADVQAQldALNKQKLLEAEDKLVQQDLEQTLALLdKIDRQKEETEQLKQQLAQAPAK---LRQAQAEL 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1019 TDAPGPELQALRAEISKLEqqCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEkarelghNQAASASAQRELQA 1098
Cdd:PRK11281   104 EALKDDNDEETRETLSTLS--LRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPER-------AQAALYANSQRLQQ 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1099 LRAKAQDhSKAEEEWKAQVARGQQEAErksslISSLEEEVSiLNRQVLEKEGESKELKRLVVAE-SEKSQKLEERLRLLQ 1177
Cdd:PRK11281   175 IRNLLKG-GKVGGKALRPSQRVLLQAE-----QALLNAQND-LQRKSLEGNTQLQDLLQKQRDYlTARIQRLEHQLQLLQ 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1178 veTASNSARAAErSSALREEVQSLREEVEKQR---VVSENSR-----QELASQAERAEELGQE---LKAWQEKFFQKEQA 1246
Cdd:PRK11281   248 --EAINSKRLTL-SEKTVQEAQSQDEAARIQAnplVAQELEInlqlsQRLLKATEKLNTLTQQnlrVKNWLDRLTQSERN 324


                   ....*....
gi 1907176327 1247 L----SALQ 1251
Cdd:PRK11281   325 IkeqiSVLK 333
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 529-731 9.46e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 9.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  529 ANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQL-KAEQQKTTEREKVVQEKAQLQEQLR 607
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIdKLQAEIAEAEAEIEERREELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  608 AL-EESLKITKGSLEEEKRRAADALKEQQCRATEMEAEsRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEA 686
Cdd:COG3883     94 ALyRSGGSVSYLDVLLGSESFSDFLDRLSALSKIADAD-ADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE 172

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1907176327  687 LRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGA 731
Cdd:COG3883    173 LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 590-712 9.82e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 40.84  E-value: 9.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  590 TEREKVVQEKAQLQEQLRALEeslkITKGSLEEEKRRAADAlkeqqcRATEMEAESRSLMEQREREQKELEQEKAGRKGL 669
Cdd:COG0542    404 MEIDSKPEELDELERRLEQLE----IEKEALKKEQDEASFE------RLAELRDELAELEEELEALKARWEAEKELIEEI 473

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1907176327  670 EARIQQLEEAHQaETEALRHELAEATAsqhrAESECERLIREV 712
Cdd:COG0542    474 QELKEELEQRYG-KIPELEKELAELEE----ELAELAPLLREE 511
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 260-771 9.85e-03

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 40.83  E-value: 9.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  260 EWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDqatrLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQ 339
Cdd:pfam05622   11 ELAQRCHELDQQVSLLQEEKNSLQQENKKLQERLDQLES----GDDSGTPGGKKYLLLQKQLEQLQEENFRLETARDDYR 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  340 TRVETLECE----------------------------------RGKQEAQLLAERSRFEDE---KQQLASLIADLQSSVS 382
Cdd:pfam05622   87 IKCEELEKEvlelqhrneeltslaeeaqalkdemdilressdkVKKLEATVETYKKKLEDLgdlRRQVKLLEERNAEYMQ 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  383 NLSQAKEELEQASQAQGaQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQ---AAQGLRQQVEQLS 459
Cdd:pfam05622  167 RTLQLEEELKKANALRG-QLETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKLEALQKEKERliiERDTLRETNEELR 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  460 -SSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQT 538
Cdd:pfam05622  246 cAQLQQAELSQADALLSPSSDPGDNLAAEIMPAEIREKLIRLQHENKMLRLGQEGSYRERLTELQQLLEDANRRKNELET 325

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  539 SVTQAQQEKAELSQKIGELhacieashQEQRQVQARVTELEAQLKaeqqktterekvvQEKAQLQEQLRALEESLKITKG 618
Cdd:pfam05622  326 QNRLANQRILELQQQVEEL--------QKALQEQGSKAEDSSLLK-------------QKLEEHLEKLHEAQSELQKKKE 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  619 SLEEekrRAADALKEQQCRATEMEAESRS----LMEQREREQKELEQEKAGRKGLEARIQQleeAHQAETEALRHELAEA 694
Cdd:pfam05622  385 QIEE---LEPKQDSNLAQKIDELQEALRKkdedMKAMEERYKKYVEKAKSVIKTLDPKQNP---ASPPEIQALKNQLLEK 458

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327  695 TASQHRAESECE--RLIREVEsrqkrfearqqeearygamfqEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQ 771
Cdd:pfam05622  459 DKKIEHLERDFEksKLQREQE---------------------EKLIVTAWYNMGMALHRKAIEERLAGLSSPGQSFLAR 516
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 846-1565 9.90e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.19  E-value: 9.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  846 QLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERG--QAQADLAQEKAAKA 923
Cdd:TIGR00606  287 ELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGrlQLQADRHQEHIRAR 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  924 ELEMRLQNTLNE----QRVEFAALQEALAHALTEKEGTD------QELAKLRGQEAAQ-------RTELKELQQTLEQLK 986
Cdd:TIGR00606  367 DSLIQSLATRLEldgfERGPFSERQIKNFHTLVIERQEDeaktaaQLCADLQSKERLKqeqadeiRDEKKGLGRTIELKK 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  987 IQLVKKEKEHPAGGASGEDASGpgtQSETAGKTDApgpELQALRAEISKLEQQCQqqqqqVEGLTHSLKSERACRAEQDK 1066
Cdd:TIGR00606  447 EILEKKQEELKFVIKELQQLEG---SSDRILELDQ---ELRKAERELSKAEKNSL-----TETLKKEVKSLQNEKADLDR 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1067 ALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVA------RGQQEAERKSSLISSLEEEVSI 1140
Cdd:TIGR00606  516 KLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGyfpnkkQLEDWLHSKSKEINQTRDRLAK 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1141 LNRQVLEKEGE----SKELKRLVVAESEKSQKLEERLRLLQVEtaSNSARAAERSSALREEVQSLREEVEKQRVVSENSR 1216
Cdd:TIGR00606  596 LNKELASLEQNknhiNNELESKEEQLSSYEDKLFDVCGSQDEE--SDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLT 673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1217 QELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAA 1296
Cdd:TIGR00606  674 DENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKL 753

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1297 GGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEkASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFleVELDQA 1376
Cdd:TIGR00606  754 QKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTD-VTIMERFQMELKDVERKIAQQAAKLQGSDLDRTV--QQVNQE 830

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1377 REKYVQELAAVRTDAEThLAEMRQEAQSTSRELEVMTAKYEGAKVKV---LEERQRFQEERQKLTAQVEQL--------- 1444
Cdd:TIGR00606  831 KQEKQHELDTVVSKIEL-NRKLIQDQQEQIQHLKSKTNELKSEKLQIgtnLQRRQQFEEQLVELSTEVQSLireikdake 909

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327 1445 ------EVFQREQTKQVEELSKKLTEHDQAS-KVQQQKLKAFQ-----------AQRGESQQEVQRlQTQLNELQAQLSQ 1506
Cdd:TIGR00606  910 qdspleTFLEKDQQEKEELISSKETSNKKAQdKVNDIKEKVKNihgymkdienkIQDGKDDYLKQK-ETELNTVNAQLEE 988

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176327 1507 KEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQdLEELQKENKELRSEAERLGRELQQ 1565
Cdd:TIGR00606  989 CEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLT-LRKRENELKEVEEELKQHLKEMGQ 1046
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 505-693 1.00e-02

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.19  E-value: 1.00e-02
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  505 RQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEK----------AELSQKIGELHA---------CIEASH 565
Cdd:PRK10929    29 TQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQqvidnfpklsAELRQQLNNERDeprsvppnmSTDALE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176327  566 QEQRQVQARVTELEAQLKAEQQKTTE-REKVVQEKAQLQEQLRALEE------SLKITKGSLEEEKRRAADA-LKEQQCR 637
Cdd:PRK10929   109 QEILQVSSQLLEKSRQAQQEQDRAREiSDSLSQLPQQQTEARRQLNEierrlqTLGTPNTPLAQAQLTALQAeSAALKAL 188

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907176327  638 ATEMEAESRSLMEQRE--REQKELEQEKAGRkgLEARIQ----QLEEAHQAETE-ALRH--ELAE 693
Cdd:PRK10929   189 VDELELAQLSANNRQElaRLRSELAKKRSQQ--LDAYLQalrnQLNSQRQREAErALESteLLAE 251
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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