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Conserved domains on  [gi|1907080738|ref|XP_036012374|]
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schlafen 4 isoform X2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA02782 super family cl31504
hypothetical protein; Provisional
35-325 4.33e-54

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PHA02782:

Pssm-ID: 165147 [Multi-domain]  Cd Length: 503  Bit Score: 190.65  E-value: 4.33e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738  35 QLRRKEAKSILQAVCTLLNSGGGVVKAHIKNQNYSFTrdgmgldLVNPLPGILHL---PHDYLDFMQYNDYFFVFVKPwk 111
Cdd:PHA02782  200 KLGENDTENLSTSISALLNSGGGTIEVTSKEERVDYV-------LMKRLESIRHLwsvVYDHFNVVNGKERCYIHMHS-- 270
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738 112 pNQRGPGIATWKTNLYKRIFSFSVELKAADAVQFLKSRPSSHGK-----------------TVCNETLNEclSLFNRDWL 174
Cdd:PHA02782  271 -SNQSPMPSTVKTNLYMKTMGSCLQMDSMEALEYLSELKESGGRsprpelpefeypdgvedTGSIERLAE--EFFNRSEL 347
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738 175 AYEETFCFTKSTHaeVKLTPKEKISPKEKILELLPQTVSAFANTDGGYLFIGLDGKTQQIIGFEAEKSDLVLLESEIEKC 254
Cdd:PHA02782  348 QAGESVKFGNSIN--VKHTSVSAKQLRTRIRQQLPSILSSFANTEGGYLFIGVDNNTHKVIGFTVGQDYLKLVENDIEKY 425
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907080738 255 IQQLPVTHFCEEKEKIKYTCKFIEVHKSG--AVCAYVCAIRVEKFCCAVFAAEPESWHVEGSCVKRFTTEEWV 325
Cdd:PHA02782  426 IKRLRVVHFCEKKEDIKYACRFIKVYKPGeeTTSTYVCAIKVERCCCAVFADWPESWYMDTSGIKKYSPDEWV 498
 
Name Accession Description Interval E-value
PHA02782 PHA02782
hypothetical protein; Provisional
35-325 4.33e-54

hypothetical protein; Provisional


Pssm-ID: 165147 [Multi-domain]  Cd Length: 503  Bit Score: 190.65  E-value: 4.33e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738  35 QLRRKEAKSILQAVCTLLNSGGGVVKAHIKNQNYSFTrdgmgldLVNPLPGILHL---PHDYLDFMQYNDYFFVFVKPwk 111
Cdd:PHA02782  200 KLGENDTENLSTSISALLNSGGGTIEVTSKEERVDYV-------LMKRLESIRHLwsvVYDHFNVVNGKERCYIHMHS-- 270
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738 112 pNQRGPGIATWKTNLYKRIFSFSVELKAADAVQFLKSRPSSHGK-----------------TVCNETLNEclSLFNRDWL 174
Cdd:PHA02782  271 -SNQSPMPSTVKTNLYMKTMGSCLQMDSMEALEYLSELKESGGRsprpelpefeypdgvedTGSIERLAE--EFFNRSEL 347
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738 175 AYEETFCFTKSTHaeVKLTPKEKISPKEKILELLPQTVSAFANTDGGYLFIGLDGKTQQIIGFEAEKSDLVLLESEIEKC 254
Cdd:PHA02782  348 QAGESVKFGNSIN--VKHTSVSAKQLRTRIRQQLPSILSSFANTEGGYLFIGVDNNTHKVIGFTVGQDYLKLVENDIEKY 425
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907080738 255 IQQLPVTHFCEEKEKIKYTCKFIEVHKSG--AVCAYVCAIRVEKFCCAVFAAEPESWHVEGSCVKRFTTEEWV 325
Cdd:PHA02782  426 IKRLRVVHFCEKKEDIKYACRFIKVYKPGeeTTSTYVCAIKVERCCCAVFADWPESWYMDTSGIKKYSPDEWV 498
AlbA_2 pfam04326
Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.
195-311 8.35e-11

Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.


Pssm-ID: 461263  Cd Length: 116  Bit Score: 59.24  E-value: 8.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738 195 KEKISPKEKilELLPQTVSAFANTDGGYLFIGLDgKTQQIIGFEAEksdlvllESEIEKCIQQLPVTHFceeKEKIKYTC 274
Cdd:pfam04326   8 KESLGKSSK--KKIAKTISAFANTEGGTIVIGVD-DTGKIVGVSDD-------EKDTEDLLKNQILDLI---KPPIEVDI 74
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1907080738 275 KFIEVHKsgavcAYVCAIRVEKFCCAVFAAEPESWHV 311
Cdd:pfam04326  75 EEIEIDG-----KYVLVVEIPEGKLKPYYTNKGEVYI 106
COG2865 COG2865
Predicted transcriptional regulator, contains HTH domain [Transcription];
195-282 2.15e-08

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 442112  Cd Length: 123  Bit Score: 52.58  E-value: 2.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738 195 KEKISPKEKILEllpqTVSAFANTDGGYLFIGLDGKTqQIIGFEAEKSDLVLLESEIEKCIQQLPVTHFCEEKEKIKYTC 274
Cdd:COG2865    18 KESLNEPDEILK----TVCAFANTEGGTLLIGVDDDG-EIVGLDDPDKLLERLENLIADNISPPIRPDVEEVEIDGKRVL 92

                  ....*...
gi 1907080738 275 KfIEVHKS 282
Cdd:COG2865    93 V-IEVPPG 99
 
Name Accession Description Interval E-value
PHA02782 PHA02782
hypothetical protein; Provisional
35-325 4.33e-54

hypothetical protein; Provisional


Pssm-ID: 165147 [Multi-domain]  Cd Length: 503  Bit Score: 190.65  E-value: 4.33e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738  35 QLRRKEAKSILQAVCTLLNSGGGVVKAHIKNQNYSFTrdgmgldLVNPLPGILHL---PHDYLDFMQYNDYFFVFVKPwk 111
Cdd:PHA02782  200 KLGENDTENLSTSISALLNSGGGTIEVTSKEERVDYV-------LMKRLESIRHLwsvVYDHFNVVNGKERCYIHMHS-- 270
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738 112 pNQRGPGIATWKTNLYKRIFSFSVELKAADAVQFLKSRPSSHGK-----------------TVCNETLNEclSLFNRDWL 174
Cdd:PHA02782  271 -SNQSPMPSTVKTNLYMKTMGSCLQMDSMEALEYLSELKESGGRsprpelpefeypdgvedTGSIERLAE--EFFNRSEL 347
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738 175 AYEETFCFTKSTHaeVKLTPKEKISPKEKILELLPQTVSAFANTDGGYLFIGLDGKTQQIIGFEAEKSDLVLLESEIEKC 254
Cdd:PHA02782  348 QAGESVKFGNSIN--VKHTSVSAKQLRTRIRQQLPSILSSFANTEGGYLFIGVDNNTHKVIGFTVGQDYLKLVENDIEKY 425
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907080738 255 IQQLPVTHFCEEKEKIKYTCKFIEVHKSG--AVCAYVCAIRVEKFCCAVFAAEPESWHVEGSCVKRFTTEEWV 325
Cdd:PHA02782  426 IKRLRVVHFCEKKEDIKYACRFIKVYKPGeeTTSTYVCAIKVERCCCAVFADWPESWYMDTSGIKKYSPDEWV 498
AlbA_2 pfam04326
Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.
195-311 8.35e-11

Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.


Pssm-ID: 461263  Cd Length: 116  Bit Score: 59.24  E-value: 8.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738 195 KEKISPKEKilELLPQTVSAFANTDGGYLFIGLDgKTQQIIGFEAEksdlvllESEIEKCIQQLPVTHFceeKEKIKYTC 274
Cdd:pfam04326   8 KESLGKSSK--KKIAKTISAFANTEGGTIVIGVD-DTGKIVGVSDD-------EKDTEDLLKNQILDLI---KPPIEVDI 74
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1907080738 275 KFIEVHKsgavcAYVCAIRVEKFCCAVFAAEPESWHV 311
Cdd:pfam04326  75 EEIEIDG-----KYVLVVEIPEGKLKPYYTNKGEVYI 106
COG2865 COG2865
Predicted transcriptional regulator, contains HTH domain [Transcription];
195-282 2.15e-08

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 442112  Cd Length: 123  Bit Score: 52.58  E-value: 2.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080738 195 KEKISPKEKILEllpqTVSAFANTDGGYLFIGLDGKTqQIIGFEAEKSDLVLLESEIEKCIQQLPVTHFCEEKEKIKYTC 274
Cdd:COG2865    18 KESLNEPDEILK----TVCAFANTEGGTLLIGVDDDG-EIVGLDDPDKLLERLENLIADNISPPIRPDVEEVEIDGKRVL 92

                  ....*...
gi 1907080738 275 KfIEVHKS 282
Cdd:COG2865    93 V-IEVPPG 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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