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Conserved domains on  [gi|1907133065|ref|XP_036017612|]
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dipeptidyl peptidase 3 isoform X1 [Mus musculus]

Protein Classification

dipeptidyl peptidase 3( domain architecture ID 10507915)

dipeptidyl peptidase 3 is an M49 family metallopeptidase that catalyzes the release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Peptidase_M49 pfam03571
Peptidase family M49;
1-428 0e+00

Peptidase family M49;


:

Pssm-ID: 460976  Cd Length: 550  Bit Score: 801.31  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065   1 MLAQYVESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKAMSAKFERLVASAEQLLKE 80
Cdd:pfam03571 128 MLEKYIESFETGSIEAHKDSQRHWVKDKGPVVETNIGFIETYRDPAGVRGEFEGFVAIVNKERSAKFGKLVDNAEKFIPL 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065  81 LPWPLAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVayAAKREKLTFLEEEDKDLYI 160
Cdd:pfam03571 208 LPWPKDFEKDKFLKPDFTSLEVLTFAGSGIPAGINIPNYDDIRQNEGFKNVSLGNVLSA--KAPNEKITFISEEDQELYK 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065 161 RWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDKETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGL 240
Cdd:pfam03571 286 KYRDPAFEVQVGLHELLGHGSGKLLQETADGKFNFDKENPPNPLTGKPITSWYKPGETWGSVFGSLASSYEECRAECVAL 365

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065 241 YLCLNPQVLEIFGFEGA-DAEDVIYVNWLNMVRAGLLALEFYTPEAANWRQAHMQARFVILRVLLEAGE-GLVTVTPTTG 318
Cdd:pfam03571 366 YLSLNKEVLEIFGFTDKeEADDVIYVNWLQMARAGLLALEFYDPETKKWGQAHMQARFAILKVLLEAGDaGFVKLEETKD 445

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065 319 SDgrPDARVRLDRSKIRSVGRPALERFLRRLQVLKSTGDVVAGRALYEGYAAVTdappECFLTLRDTVLLRKESRKLIVQ 398
Cdd:pfam03571 446 ED--SDLTIRLDRSKILTVGKPAIGDFLLKLQVYKSTADVEAGTEFYEDYTTVD----EEFLKWRDIVLAKKQPRKVFVQ 519

                         410       420       430
                  ....*....|....*....|....*....|.
gi 1907133065 399 PNTRLE-GSEVQLVEYEASAAGLIRSFCERF 428
Cdd:pfam03571 520 ANTVLNdGGKVELKEYEETPEGMIQSFVERF 550
 
Name Accession Description Interval E-value
Peptidase_M49 pfam03571
Peptidase family M49;
1-428 0e+00

Peptidase family M49;


Pssm-ID: 460976  Cd Length: 550  Bit Score: 801.31  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065   1 MLAQYVESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKAMSAKFERLVASAEQLLKE 80
Cdd:pfam03571 128 MLEKYIESFETGSIEAHKDSQRHWVKDKGPVVETNIGFIETYRDPAGVRGEFEGFVAIVNKERSAKFGKLVDNAEKFIPL 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065  81 LPWPLAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVayAAKREKLTFLEEEDKDLYI 160
Cdd:pfam03571 208 LPWPKDFEKDKFLKPDFTSLEVLTFAGSGIPAGINIPNYDDIRQNEGFKNVSLGNVLSA--KAPNEKITFISEEDQELYK 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065 161 RWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDKETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGL 240
Cdd:pfam03571 286 KYRDPAFEVQVGLHELLGHGSGKLLQETADGKFNFDKENPPNPLTGKPITSWYKPGETWGSVFGSLASSYEECRAECVAL 365

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065 241 YLCLNPQVLEIFGFEGA-DAEDVIYVNWLNMVRAGLLALEFYTPEAANWRQAHMQARFVILRVLLEAGE-GLVTVTPTTG 318
Cdd:pfam03571 366 YLSLNKEVLEIFGFTDKeEADDVIYVNWLQMARAGLLALEFYDPETKKWGQAHMQARFAILKVLLEAGDaGFVKLEETKD 445

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065 319 SDgrPDARVRLDRSKIRSVGRPALERFLRRLQVLKSTGDVVAGRALYEGYAAVTdappECFLTLRDTVLLRKESRKLIVQ 398
Cdd:pfam03571 446 ED--SDLTIRLDRSKILTVGKPAIGDFLLKLQVYKSTADVEAGTEFYEDYTTVD----EEFLKWRDIVLAKKQPRKVFVQ 519

                         410       420       430
                  ....*....|....*....|....*....|.
gi 1907133065 399 PNTRLE-GSEVQLVEYEASAAGLIRSFCERF 428
Cdd:pfam03571 520 ANTVLNdGGKVELKEYEETPEGMIQSFVERF 550
 
Name Accession Description Interval E-value
Peptidase_M49 pfam03571
Peptidase family M49;
1-428 0e+00

Peptidase family M49;


Pssm-ID: 460976  Cd Length: 550  Bit Score: 801.31  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065   1 MLAQYVESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKAMSAKFERLVASAEQLLKE 80
Cdd:pfam03571 128 MLEKYIESFETGSIEAHKDSQRHWVKDKGPVVETNIGFIETYRDPAGVRGEFEGFVAIVNKERSAKFGKLVDNAEKFIPL 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065  81 LPWPLAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVayAAKREKLTFLEEEDKDLYI 160
Cdd:pfam03571 208 LPWPKDFEKDKFLKPDFTSLEVLTFAGSGIPAGINIPNYDDIRQNEGFKNVSLGNVLSA--KAPNEKITFISEEDQELYK 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065 161 RWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDKETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGL 240
Cdd:pfam03571 286 KYRDPAFEVQVGLHELLGHGSGKLLQETADGKFNFDKENPPNPLTGKPITSWYKPGETWGSVFGSLASSYEECRAECVAL 365

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065 241 YLCLNPQVLEIFGFEGA-DAEDVIYVNWLNMVRAGLLALEFYTPEAANWRQAHMQARFVILRVLLEAGE-GLVTVTPTTG 318
Cdd:pfam03571 366 YLSLNKEVLEIFGFTDKeEADDVIYVNWLQMARAGLLALEFYDPETKKWGQAHMQARFAILKVLLEAGDaGFVKLEETKD 445

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907133065 319 SDgrPDARVRLDRSKIRSVGRPALERFLRRLQVLKSTGDVVAGRALYEGYAAVTdappECFLTLRDTVLLRKESRKLIVQ 398
Cdd:pfam03571 446 ED--SDLTIRLDRSKILTVGKPAIGDFLLKLQVYKSTADVEAGTEFYEDYTTVD----EEFLKWRDIVLAKKQPRKVFVQ 519

                         410       420       430
                  ....*....|....*....|....*....|.
gi 1907133065 399 PNTRLE-GSEVQLVEYEASAAGLIRSFCERF 428
Cdd:pfam03571 520 ANTVLNdGGKVELKEYEETPEGMIQSFVERF 550
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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