|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
452-565 |
5.02e-29 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
:
Pssm-ID: 461796 Cd Length: 115 Bit Score: 112.29 E-value: 5.02e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 452 LVSGNLTdRGGPLGYQKILWIPAGASHLRISQFRPSSNYLALRGPGGRSIINGNWAVDP-PGSYAAVGTVFQYNRPPREe 530
Cdd:pfam05986 1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78
|
90 100 110
....*....|....*....|....*....|....*...
gi 1958750789 531 gkGETLSAEGPTTQPVDVYMIFQED---NPGVFYQYVT 565
Cdd:pfam05986 79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
690-746 |
2.74e-15 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 70.94 E-value: 2.74e-15
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958750789 690 WEAGEWTSCSRSCGPGTQHRQLLCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 746
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
875-931 |
4.83e-13 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 64.40 E-value: 4.83e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958750789 875 WYTGPWSECSSECGSGTQHRDIICVSKLGtkFNVTSPSNCSHLPRPPALQPCQGQAC 931
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGG--GSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| PLAC |
pfam08686 |
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short ... |
994-1023 |
1.85e-10 |
|
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short six-cysteine region that is usually found at the C terminal of proteins. It is found in a range of proteins including PACE4 (paired basic amino acid cleaving enzyme 4) and the extracellular matrix protein lacunin.
:
Pssm-ID: 462560 Cd Length: 31 Bit Score: 56.39 E-value: 1.85e-10
10 20 30
....*....|....*....|....*....|
gi 1958750789 994 CKDSSPHCPLVVQARLCVYPYYTATCCRSC 1023
Cdd:pfam08686 1 CKDKFANCSLVVQARLCSHKYYRQFCCRSC 30
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
808-869 |
2.51e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 56.69 E-value: 2.51e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958750789 808 WFYSDWSSkCSAECGTGIQRRAVVCLRS-GETLQGDPEagsteqgCPLRSRPPDMRACSLGPC 869
Cdd:pfam19030 1 WVAGPWGE-CSVTCGGGVQTRLVQCVQKgGGSIVPDSE-------CSAQKKPPETQSCNLKPC 55
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
24-358 |
6.76e-10 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.80 E-value: 6.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 24 DQEVSPGQLLGPSLQTPSEEDQVPEGLWGPwgrwascsQPCGVGVQRRSRTCELHPALSLP------PRPPRHPEAPQPR 97
Cdd:PHA03247 2546 DDAGDPPPPLPPAAPPAAPDRSVPPPRPAP--------RPSEPAVTSRARRPDAPPQSARPrapvddRGDPRGPAPPSPL 2617
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 98 GQGSRPQTPRDPQSLYRPQPRGRGGPLRGPASQVGREETQEPRGAQRFRVRDPIKPgmfgygrVPFALPLHRSRRLAHKP 177
Cdd:PHA03247 2618 PPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA-------AQASSPPQRPRRRAARP 2690
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 178 gqPKDSSTAEETLPSQPPSTEPASEKHSPHMQPPELRAQSRSPSAETPrsgtaQTEVPSRTSSAPSDMGIPAPTssfrds 257
Cdd:PHA03247 2691 --TVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALP-----AAPAPPAVPAGPATPGGPARP------ 2757
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 258 rsfqgspePRMPTSQGAERQPHPFSPVTRSQlsRRHWRPPGSPHRSPDGWLPLTRDSSPHWSLFAPSSPTpecsgeseqm 337
Cdd:PHA03247 2758 --------ARPPTTAGPPAPAPPAAPAAGPP--RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAA---------- 2817
|
330 340
....*....|....*....|.
gi 1958750789 338 RACSQEPCPPEQPDPRALQCA 358
Cdd:PHA03247 2818 LPPAASPAGPLPPPTSAQPTA 2838
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
935-986 |
2.79e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 54.00 E-value: 2.79e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1958750789 935 WFSTLWSPCSQSCQGGVQTREVQCL-SSNHTL--SSRCPPHLRPSRKRPCNSQPC 986
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVqKGGGSIvpDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
754-804 |
3.81e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 50.53 E-value: 3.81e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1958750789 754 PWSQCSVRCGRGQRSRQVRCVGSNGHEVGKQECASGPPPPPSREACDMGPC 804
Cdd:pfam19030 5 PWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
637-686 |
1.62e-05 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 43.21 E-value: 1.62e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1958750789 637 SECSASCGKGVWRPIFLCVSRESGEELDEQSCAVGARPPASpESCHRPPC 686
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
|
|
| ADAMTS_CR_3 super family |
cl41950 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
356-450 |
2.42e-04 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
The actual alignment was detected with superfamily member pfam19236:
Pssm-ID: 437068 Cd Length: 115 Bit Score: 41.62 E-value: 2.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 356 QCAAFDSQEFM-----GQLYQW-EPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQP------GSLDICVAGHCL 423
Cdd:pfam19236 9 QCARTDGQPLRsspggASFYHWgAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPsgpredGTLSLCVLGSCR 88
|
90 100
....*....|....*....|....*..
gi 1958750789 424 SPGCDGILGSGRRPDGCGVCGGDGSTC 450
Cdd:pfam19236 89 TFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
452-565 |
5.02e-29 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
Pssm-ID: 461796 Cd Length: 115 Bit Score: 112.29 E-value: 5.02e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 452 LVSGNLTdRGGPLGYQKILWIPAGASHLRISQFRPSSNYLALRGPGGRSIINGNWAVDP-PGSYAAVGTVFQYNRPPREe 530
Cdd:pfam05986 1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78
|
90 100 110
....*....|....*....|....*....|....*...
gi 1958750789 531 gkGETLSAEGPTTQPVDVYMIFQED---NPGVFYQYVT 565
Cdd:pfam05986 79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
690-746 |
2.74e-15 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 70.94 E-value: 2.74e-15
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958750789 690 WEAGEWTSCSRSCGPGTQHRQLLCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 746
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
875-931 |
4.83e-13 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 64.40 E-value: 4.83e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958750789 875 WYTGPWSECSSECGSGTQHRDIICVSKLGtkFNVTSPSNCSHLPRPPALQPCQGQAC 931
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGG--GSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| PLAC |
pfam08686 |
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short ... |
994-1023 |
1.85e-10 |
|
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short six-cysteine region that is usually found at the C terminal of proteins. It is found in a range of proteins including PACE4 (paired basic amino acid cleaving enzyme 4) and the extracellular matrix protein lacunin.
Pssm-ID: 462560 Cd Length: 31 Bit Score: 56.39 E-value: 1.85e-10
10 20 30
....*....|....*....|....*....|
gi 1958750789 994 CKDSSPHCPLVVQARLCVYPYYTATCCRSC 1023
Cdd:pfam08686 1 CKDKFANCSLVVQARLCSHKYYRQFCCRSC 30
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
808-869 |
2.51e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 56.69 E-value: 2.51e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958750789 808 WFYSDWSSkCSAECGTGIQRRAVVCLRS-GETLQGDPEagsteqgCPLRSRPPDMRACSLGPC 869
Cdd:pfam19030 1 WVAGPWGE-CSVTCGGGVQTRLVQCVQKgGGSIVPDSE-------CSAQKKPPETQSCNLKPC 55
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
24-358 |
6.76e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.80 E-value: 6.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 24 DQEVSPGQLLGPSLQTPSEEDQVPEGLWGPwgrwascsQPCGVGVQRRSRTCELHPALSLP------PRPPRHPEAPQPR 97
Cdd:PHA03247 2546 DDAGDPPPPLPPAAPPAAPDRSVPPPRPAP--------RPSEPAVTSRARRPDAPPQSARPrapvddRGDPRGPAPPSPL 2617
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 98 GQGSRPQTPRDPQSLYRPQPRGRGGPLRGPASQVGREETQEPRGAQRFRVRDPIKPgmfgygrVPFALPLHRSRRLAHKP 177
Cdd:PHA03247 2618 PPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA-------AQASSPPQRPRRRAARP 2690
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 178 gqPKDSSTAEETLPSQPPSTEPASEKHSPHMQPPELRAQSRSPSAETPrsgtaQTEVPSRTSSAPSDMGIPAPTssfrds 257
Cdd:PHA03247 2691 --TVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALP-----AAPAPPAVPAGPATPGGPARP------ 2757
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 258 rsfqgspePRMPTSQGAERQPHPFSPVTRSQlsRRHWRPPGSPHRSPDGWLPLTRDSSPHWSLFAPSSPTpecsgeseqm 337
Cdd:PHA03247 2758 --------ARPPTTAGPPAPAPPAAPAAGPP--RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAA---------- 2817
|
330 340
....*....|....*....|.
gi 1958750789 338 RACSQEPCPPEQPDPRALQCA 358
Cdd:PHA03247 2818 LPPAASPAGPLPPPTSAQPTA 2838
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
935-986 |
2.79e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 54.00 E-value: 2.79e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1958750789 935 WFSTLWSPCSQSCQGGVQTREVQCL-SSNHTL--SSRCPPHLRPSRKRPCNSQPC 986
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVqKGGGSIvpDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
754-804 |
3.81e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 50.53 E-value: 3.81e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1958750789 754 PWSQCSVRCGRGQRSRQVRCVGSNGHEVGKQECASGPPPPPSREACDMGPC 804
Cdd:pfam19030 5 PWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
51-80 |
1.34e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 43.34 E-value: 1.34e-05
10 20 30
....*....|....*....|....*....|
gi 1958750789 51 WGPWGRWASCSQPCGVGVQRRSRTCELHPA 80
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPP 30
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
637-686 |
1.62e-05 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 43.21 E-value: 1.62e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1958750789 637 SECSASCGKGVWRPIFLCVSRESGEELDEQSCAVGARPPASpESCHRPPC 686
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
74-328 |
3.10e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 48.22 E-value: 3.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 74 TCELHPALSLPPRPPRHPEAPQPrgqgsrPQTPRDPQSLYRPQPRGRGGPLRGPAsQVGREETQEPRGAQRFrvrdPIKP 153
Cdd:pfam03154 234 TPTLHPQRLPSPHPPLQPMTQPP------PPSQVSPQPLPQPSLHGQMPPMPHSL-QTGPSHMQHPVPPQPF----PLTP 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 154 GMfGYGRVP----FALPLHRSRRLAHKPGQPKDSstaeetlPSQPPSTE--PASEKHSPHMQPPelraqsrsPSAETPRS 227
Cdd:pfam03154 303 QS-SQSQVPpgpsPAAPGQSQQRIHTPPSQSQLQ-------SQQPPREQplPPAPLSMPHIKPP--------PTTPIPQL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 228 GTAQTEVPSRTSSAPSDMGIPA---------PTSSFRDSRSFQGSPEPRMPTSQGAERQPHPFSPVTRSQlsRRHWRPPG 298
Cdd:pfam03154 367 PNPQSHKHPPHLSGPSPFQMNSnlppppalkPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQ--SQSLPPPA 444
|
250 260 270
....*....|....*....|....*....|
gi 1958750789 299 SPHRSPDGWLPLTRDSSPHWSLFAPSSPTP 328
Cdd:pfam03154 445 ASHPPTSGLHQVPSQSPFPQHPFVPGGPPP 474
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
940-986 |
5.61e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 41.80 E-value: 5.61e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1958750789 940 WSPCSQSCQGGVQTREVQCLSSNHTLS-SRCPPHLRpsRKRPCNSQPC 986
Cdd:smart00209 7 WSPCSVTCGGGVQTRTRSCCSPPPQNGgGPCTGEDV--ETRACNEQPC 52
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
746-804 |
9.64e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 41.03 E-value: 9.64e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1958750789 746 CGHWeisSPWSQCSVRCGRGQRSRQVRCVGSNGHEVGkQECasgPPPPPSREACDMGPC 804
Cdd:smart00209 1 WSEW---SEWSPCSVTCGGGVQTRTRSCCSPPPQNGG-GPC---TGEDVETRACNEQPC 52
|
|
| ADAMTS_CR_3 |
pfam19236 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
356-450 |
2.42e-04 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
Pssm-ID: 437068 Cd Length: 115 Bit Score: 41.62 E-value: 2.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 356 QCAAFDSQEFM-----GQLYQW-EPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQP------GSLDICVAGHCL 423
Cdd:pfam19236 9 QCARTDGQPLRsspggASFYHWgAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPsgpredGTLSLCVLGSCR 88
|
90 100
....*....|....*....|....*..
gi 1958750789 424 SPGCDGILGSGRRPDGCGVCGGDGSTC 450
Cdd:pfam19236 89 TFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| PTZ00441 |
PTZ00441 |
sporozoite surface protein 2 (SSP2); Provisional |
746-794 |
6.73e-03 |
|
sporozoite surface protein 2 (SSP2); Provisional
Pssm-ID: 240420 [Multi-domain] Cd Length: 576 Bit Score: 40.33 E-value: 6.73e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1958750789 746 CGHWEissPWSQCSVRCGRGQRSRQ-----VRCVGSNGHEVGKQECASGPPPPP 794
Cdd:PTZ00441 240 CGPWD---EWTPCSVTCGKGTHSRSrpilhEGCTTHMVEECEEEECPVEPEPLP 290
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
452-565 |
5.02e-29 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
Pssm-ID: 461796 Cd Length: 115 Bit Score: 112.29 E-value: 5.02e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 452 LVSGNLTdRGGPLGYQKILWIPAGASHLRISQFRPSSNYLALRGPGGRSIINGNWAVDP-PGSYAAVGTVFQYNRPPREe 530
Cdd:pfam05986 1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78
|
90 100 110
....*....|....*....|....*....|....*...
gi 1958750789 531 gkGETLSAEGPTTQPVDVYMIFQED---NPGVFYQYVT 565
Cdd:pfam05986 79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
690-746 |
2.74e-15 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 70.94 E-value: 2.74e-15
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958750789 690 WEAGEWTSCSRSCGPGTQHRQLLCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 746
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
875-931 |
4.83e-13 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 64.40 E-value: 4.83e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958750789 875 WYTGPWSECSSECGSGTQHRDIICVSKLGtkFNVTSPSNCSHLPRPPALQPCQGQAC 931
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGG--GSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| PLAC |
pfam08686 |
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short ... |
994-1023 |
1.85e-10 |
|
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short six-cysteine region that is usually found at the C terminal of proteins. It is found in a range of proteins including PACE4 (paired basic amino acid cleaving enzyme 4) and the extracellular matrix protein lacunin.
Pssm-ID: 462560 Cd Length: 31 Bit Score: 56.39 E-value: 1.85e-10
10 20 30
....*....|....*....|....*....|
gi 1958750789 994 CKDSSPHCPLVVQARLCVYPYYTATCCRSC 1023
Cdd:pfam08686 1 CKDKFANCSLVVQARLCSHKYYRQFCCRSC 30
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
808-869 |
2.51e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 56.69 E-value: 2.51e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958750789 808 WFYSDWSSkCSAECGTGIQRRAVVCLRS-GETLQGDPEagsteqgCPLRSRPPDMRACSLGPC 869
Cdd:pfam19030 1 WVAGPWGE-CSVTCGGGVQTRLVQCVQKgGGSIVPDSE-------CSAQKKPPETQSCNLKPC 55
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
24-358 |
6.76e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.80 E-value: 6.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 24 DQEVSPGQLLGPSLQTPSEEDQVPEGLWGPwgrwascsQPCGVGVQRRSRTCELHPALSLP------PRPPRHPEAPQPR 97
Cdd:PHA03247 2546 DDAGDPPPPLPPAAPPAAPDRSVPPPRPAP--------RPSEPAVTSRARRPDAPPQSARPrapvddRGDPRGPAPPSPL 2617
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 98 GQGSRPQTPRDPQSLYRPQPRGRGGPLRGPASQVGREETQEPRGAQRFRVRDPIKPgmfgygrVPFALPLHRSRRLAHKP 177
Cdd:PHA03247 2618 PPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA-------AQASSPPQRPRRRAARP 2690
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 178 gqPKDSSTAEETLPSQPPSTEPASEKHSPHMQPPELRAQSRSPSAETPrsgtaQTEVPSRTSSAPSDMGIPAPTssfrds 257
Cdd:PHA03247 2691 --TVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALP-----AAPAPPAVPAGPATPGGPARP------ 2757
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 258 rsfqgspePRMPTSQGAERQPHPFSPVTRSQlsRRHWRPPGSPHRSPDGWLPLTRDSSPHWSLFAPSSPTpecsgeseqm 337
Cdd:PHA03247 2758 --------ARPPTTAGPPAPAPPAAPAAGPP--RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAA---------- 2817
|
330 340
....*....|....*....|.
gi 1958750789 338 RACSQEPCPPEQPDPRALQCA 358
Cdd:PHA03247 2818 LPPAASPAGPLPPPTSAQPTA 2838
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
935-986 |
2.79e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 54.00 E-value: 2.79e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1958750789 935 WFSTLWSPCSQSCQGGVQTREVQCL-SSNHTL--SSRCPPHLRPSRKRPCNSQPC 986
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVqKGGGSIvpDSECSAQKKPPETQSCNLKPC 55
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
40-354 |
9.98e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 59.95 E-value: 9.98e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 40 PSEEDQVPEGLWGPWGRWASCSQPCGVGVQRRSRTCELHPALSLPPRPPRHPEAPQPRGQGSRPQTPRDPQSLYRPQPRG 119
Cdd:PHA03247 2635 ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHA 2714
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 120 RGGPLRGPASqvgreeTQEPRGAQRFRVRDPIKPGMFGYGRVPFALplhrsrrlAHKPGQPKDSSTAEETLPSQPPSTEP 199
Cdd:PHA03247 2715 LVSATPLPPG------PAAARQASPALPAAPAPPAVPAGPATPGGP--------ARPARPPTTAGPPAPAPPAAPAAGPP 2780
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 200 ASEKHSPHMQPPELRAQSRSPSAETPRSGTAQTEVPSRTSSAPSDMGIPAPTSS-----------FRDSRSFQGSPEPRM 268
Cdd:PHA03247 2781 RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAqptapppppgpPPPSLPLGGSVAPGG 2860
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 269 PTSQGAERQPHPFSPVTRSQL-SRRHWRPPGSPHRSPDGWLPLTRDSSPHWSLFAPSSPTPECSGESEQMRACSQEPCPP 347
Cdd:PHA03247 2861 DVRRRPPSRSPAAKPAAPARPpVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ 2940
|
....*..
gi 1958750789 348 EQPDPRA 354
Cdd:PHA03247 2941 PPLAPTT 2947
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
754-804 |
3.81e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 50.53 E-value: 3.81e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1958750789 754 PWSQCSVRCGRGQRSRQVRCVGSNGHEVGKQECASGPPPPPSREACDMGPC 804
Cdd:pfam19030 5 PWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| PTZ00441 |
PTZ00441 |
sporozoite surface protein 2 (SSP2); Provisional |
52-336 |
3.09e-07 |
|
sporozoite surface protein 2 (SSP2); Provisional
Pssm-ID: 240420 [Multi-domain] Cd Length: 576 Bit Score: 54.20 E-value: 3.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 52 GPWGRWASCSQPCGVGVQRRSR-------TCELHPALSLPPRPPRHPEAPQPrgqGSRPQTPRDpqslyrPQPRGRGGPL 124
Cdd:PTZ00441 241 GPWDEWTPCSVTCGKGTHSRSRpilhegcTTHMVEECEEEECPVEPEPLPVP---APVPPTPED------DNPRPTDDEF 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 125 RGPASQVGREETQEPrgaqrfrvRDPIKPGMFGYGRVPFALPLHrsrrlahkpgQPKDSSTAEET----LPSQPP--STE 198
Cdd:PTZ00441 312 AVPNFNEGLDVPDNP--------QDPVPPPNEGKDGNPNEENLF----------PPGDDEVPDESnvppNPPNVPggSNS 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 199 PASEKHSPHMQPPELRAQSRSPSAETPRSGTAQTEVPsRTSSAPSDMGIPAPTssfRDSRSFQGSPEPRMPTSQGAER-Q 277
Cdd:PTZ00441 374 EFSSDVENPPNPPNPDIPEQEPNIPEDSNKEVPEDVP-MEPEDDRDNNFNEPK---KPENKGDGQNEPVIPKPLDNERdQ 449
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1958750789 278 PHPFSPVTRSQLSRRHWRPPgSPHRSPDGWlpltrDSSPHWSLFAPSSPTPEcsgESEQ 336
Cdd:PTZ00441 450 SNKNKQVNPGNRHNSEDRYT-RPHGRNNEN-----RNYNNKNSDIPKHPERS---EHEQ 499
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
70-353 |
3.58e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 54.41 E-value: 3.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 70 RRSRTCELHPALSLPPRPPRHPEAPQPRGQGSRPQTPRDPQSlyrPQPRGRGGPLRGPASQVGREETQEPRGAQRFRVRD 149
Cdd:PHA03307 82 NESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPP---ASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGAS 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 150 PIKPGMFGYGRVPFALPLHRSRRLAHKPGQPKdsstaeetlPSQPPSTEPASEKHSPHMQPPELRAQSRSPSAETPRSGT 229
Cdd:PHA03307 159 PAAVASDAASSRQAALPLSSPEETARAPSSPP---------AEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAA 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 230 aqtevpSRTSSAPSDMGIPAPTSSFRDSRSFQGSPEPRMPTSQGAERQPHPF------SPVTRSQLSRRHWRPPGSPHRS 303
Cdd:PHA03307 230 ------DDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWngpssrPGPASSSSSPRERSPSPSPSSP 303
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1958750789 304 PDGWLPLTRDSSPHWSLFAPSSpTPECSGESEQMRACSQEPCPPEQPDPR 353
Cdd:PHA03307 304 GSGPAPSSPRASSSSSSSRESS-SSSTSSSSESSRGAAVSPGPSPSRSPS 352
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
36-328 |
4.20e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 51.09 E-value: 4.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 36 SLQTPSEEDQVPEglwgPWGRWASCSQPCGVGVQRRSRTCELHPALSLPPRPPRHPEAPQPRGQGSRPQTPRDPQSLYRP 115
Cdd:PHA03247 2697 SLADPPPPPPTPE----PAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPP 2772
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 116 QPRGRGGPLRGPASQVG-----REETQEPRGAQRFRVRDPIKPGMFGYGRVPFALPLHRSRRLAHKPGQPKDSSTAEETL 190
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVAslsesRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 191 --------------PSQPPSTEPASEKH---------------SPHMQPPELRAQSRSPSAETPRSGTAQTEVPSRTSSA 241
Cdd:PHA03247 2853 ggsvapggdvrrrpPSRSPAAKPAAPARppvrrlarpavsrstESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPP 2932
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 242 PSDMGIPAPTSSFRDSRSFQGSPEPRMPTSQGAERQPHPFsPVTRSQLSR-RHWRPPGSPHRSPDGWLPLTRDSSPHWSL 320
Cdd:PHA03247 2933 PPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRV-AVPRFRVPQpAPSREAPASSTPPLTGHSLSRVSSWASSL 3011
|
....*...
gi 1958750789 321 FAPSSPTP 328
Cdd:PHA03247 3012 ALHEETDP 3019
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
51-80 |
1.34e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 43.34 E-value: 1.34e-05
10 20 30
....*....|....*....|....*....|
gi 1958750789 51 WGPWGRWASCSQPCGVGVQRRSRTCELHPA 80
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPP 30
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
637-686 |
1.62e-05 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 43.21 E-value: 1.62e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1958750789 637 SECSASCGKGVWRPIFLCVSRESGEELDEQSCAVGARPPASpESCHRPPC 686
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
74-328 |
3.10e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 48.22 E-value: 3.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 74 TCELHPALSLPPRPPRHPEAPQPrgqgsrPQTPRDPQSLYRPQPRGRGGPLRGPAsQVGREETQEPRGAQRFrvrdPIKP 153
Cdd:pfam03154 234 TPTLHPQRLPSPHPPLQPMTQPP------PPSQVSPQPLPQPSLHGQMPPMPHSL-QTGPSHMQHPVPPQPF----PLTP 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 154 GMfGYGRVP----FALPLHRSRRLAHKPGQPKDSstaeetlPSQPPSTE--PASEKHSPHMQPPelraqsrsPSAETPRS 227
Cdd:pfam03154 303 QS-SQSQVPpgpsPAAPGQSQQRIHTPPSQSQLQ-------SQQPPREQplPPAPLSMPHIKPP--------PTTPIPQL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 228 GTAQTEVPSRTSSAPSDMGIPA---------PTSSFRDSRSFQGSPEPRMPTSQGAERQPHPFSPVTRSQlsRRHWRPPG 298
Cdd:pfam03154 367 PNPQSHKHPPHLSGPSPFQMNSnlppppalkPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQ--SQSLPPPA 444
|
250 260 270
....*....|....*....|....*....|
gi 1958750789 299 SPHRSPDGWLPLTRDSSPHWSLFAPSSPTP 328
Cdd:pfam03154 445 ASHPPTSGLHQVPSQSPFPQHPFVPGGPPP 474
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
85-291 |
3.52e-05 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 48.15 E-value: 3.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 85 PRPPRHPEAPQPRGQGSRPQTPRDPQSLYRPQPRGRGGPLRGPASQVGREETQEPRGAQRFRV----RDPIKPgmfgygR 160
Cdd:PTZ00449 591 PEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIikspKPPKSP------K 664
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 161 VPF------------------------ALPLHRSRRLAHKPGQPKDSSTAEETLPSQPPsTEPASEKhSPHMQPPELRAQ 216
Cdd:PTZ00449 665 PPFdpkfkekfyddyldaaaksketktTVVLDESFESILKETLPETPGTPFTTPRPLPP-KLPRDEE-FPFEPIGDPDAE 742
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 217 SRSPSaetpRSGTAQTEVPSRTSSAPSDMGIPAPTSSF---RDSRSFQGSPE-----PRMPTSQgAERQP--HPFSPVTR 286
Cdd:PTZ00449 743 QPDDI----EFFTPPEEERTFFHETPADTPLPDILAEEfkeEDIHAETGEPDeamkrPDSPSEH-EDKPPgdHPSLPKKR 817
|
....*
gi 1958750789 287 SQLSR 291
Cdd:PTZ00449 818 HRLDG 822
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
940-986 |
5.61e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 41.80 E-value: 5.61e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1958750789 940 WSPCSQSCQGGVQTREVQCLSSNHTLS-SRCPPHLRpsRKRPCNSQPC 986
Cdd:smart00209 7 WSPCSVTCGGGVQTRTRSCCSPPPQNGgGPCTGEDV--ETRACNEQPC 52
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
746-804 |
9.64e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 41.03 E-value: 9.64e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1958750789 746 CGHWeisSPWSQCSVRCGRGQRSRQVRCVGSNGHEVGkQECasgPPPPPSREACDMGPC 804
Cdd:smart00209 1 WSEW---SEWSPCSVTCGGGVQTRTRSCCSPPPQNGG-GPC---TGEDVETRACNEQPC 52
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
84-333 |
2.15e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.55 E-value: 2.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 84 PPRPPRHPEAPQPRGQGsRPQTPRDPQSLYRPQPRGRGG-----PLRGPASQVGREETQEPRGAQRFRVRDPiKPGMFGY 158
Cdd:PHA03307 188 SPPAEPPPSTPPAAASP-RPPRRSSPISASASSPAPAPGrsaadDAGASSSDSSSSESSGCGWGPENECPLP-RPAPITL 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 159 GRVPFALPLHRSRRLAHKPGQPkdSSTAEETLPSQPPSTEPASEKHSPHMQPPELRAQSRSPSAETPRSGTAQTEVPSRT 238
Cdd:PHA03307 266 PTRIWEASGWNGPSSRPGPASS--SSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSP 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 239 SSAPSDMGIPAPTSSFRDSRSFQGSPEPRMPTSQGAERQPHPFSPVTRSQLSRRHWRPPGSPHRSPDGWLPLTRDSSPHW 318
Cdd:PHA03307 344 GPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAAS 423
|
250
....*....|....*
gi 1958750789 319 SLFAPSSPTPECSGE 333
Cdd:PHA03307 424 GAFYARYPLLTPSGE 438
|
|
| ADAMTS_CR_3 |
pfam19236 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
356-450 |
2.42e-04 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
Pssm-ID: 437068 Cd Length: 115 Bit Score: 41.62 E-value: 2.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 356 QCAAFDSQEFM-----GQLYQW-EPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQP------GSLDICVAGHCL 423
Cdd:pfam19236 9 QCARTDGQPLRsspggASFYHWgAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPsgpredGTLSLCVLGSCR 88
|
90 100
....*....|....*....|....*..
gi 1958750789 424 SPGCDGILGSGRRPDGCGVCGGDGSTC 450
Cdd:pfam19236 89 TFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
194-352 |
2.44e-04 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 45.07 E-value: 2.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 194 PPSTEPASEKHSPHMQPPElrAQSRSPSAETPRSGTAQTEVPSRTSSAPSDMGIP------------APTSSFRDSRSFQ 261
Cdd:PTZ00449 497 APIEEEDSDKHDEPPEGPE--ASGLPPKAPGDKEGEEGEHEDSKESDEPKEGGKPgetkegevgkkpGPAKEHKPSKIPT 574
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 262 GSPEPRMPTSQGAERQPH----PFSPVTRSQLSRRhwRPPGSPHRS--PDGWLPLTRDSSPHwslfAPSSPTPECSGESE 335
Cdd:PTZ00449 575 LSKKPEFPKDPKHPKDPEepkkPKRPRSAQRPTRP--KSPKLPELLdiPKSPKRPESPKSPK----RPPPPQRPSSPERP 648
|
170
....*....|....*..
gi 1958750789 336 QMRACSQEPCPPEQPDP 352
Cdd:PTZ00449 649 EGPKIIKSPKPPKSPKP 665
|
|
| TSP1_spondin |
pfam19028 |
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ... |
940-986 |
2.99e-04 |
|
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.
Pssm-ID: 465948 Cd Length: 52 Bit Score: 39.57 E-value: 2.99e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1958750789 940 WSPCSQSCQGGVQTR--EVQCLSSNHtlSSRCPPHLrpsRKRPCNSQPC 986
Cdd:pfam19028 9 WSECSVTCGGGVQTRtrTVIVEPQNG--GRPCPELL---ERRPCNLPPC 52
|
|
| PRK13042 |
PRK13042 |
superantigen-like protein SSL4; Reviewed; |
183-264 |
3.81e-04 |
|
superantigen-like protein SSL4; Reviewed;
Pssm-ID: 183854 [Multi-domain] Cd Length: 291 Bit Score: 43.85 E-value: 3.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 183 SSTAEETLPSQPPSTEPASEKHSPHM-QPPELRAQS--RSPSAETPRSGTAQTEVPSRTSSAPSDMgipapTSSFRDSRS 259
Cdd:PRK13042 34 SSTKVEAPQSTPPSTKVEAPQSKPNAtTPPSTKVEApqQTPNATTPSSTKVETPQSPTTKQVPTEI-----NPKFKDLRA 108
|
....*
gi 1958750789 260 FQGSP 264
Cdd:PRK13042 109 YYTKP 113
|
|
| TSP1_spondin |
pfam19028 |
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ... |
52-80 |
4.48e-04 |
|
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.
Pssm-ID: 465948 Cd Length: 52 Bit Score: 39.18 E-value: 4.48e-04
10 20
....*....|....*....|....*....
gi 1958750789 52 GPWGRWASCSQPCGVGVQRRSRTCELHPA 80
Cdd:pfam19028 4 SEWSEWSECSVTCGGGVQTRTRTVIVEPQ 32
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
80-358 |
4.76e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.54 E-value: 4.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 80 ALSLPPRPPRHPEaPQPRGQGSRPQTPRDPQSLYRPQPRGRGGPLRGPASQVGREETQEPRGAQRFRVRDPIKPGMfgyG 159
Cdd:PHA03247 2697 SLADPPPPPPTPE-PAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAP---P 2772
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 160 RVPFALPLHRSRRLAHKPGQPKDSSTAEETLPSQPPSTEPASEKHSPHMQ---PPELRAQSRSPSAETPRSGTAQTEVPS 236
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAAspaGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 237 RTSSAP---------SDMGIPAPTSSFRDSRSFQGSPEPRMPTSQGAERQPHPFSPVTRSQLSRRHWRPPGSPHRSPDGW 307
Cdd:PHA03247 2853 GGSVAPggdvrrrppSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPP 2932
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1958750789 308 LPLTRDSSPHWSLFAPSSPTPECSGESEQMRACSQEPCPPEQPDPRALQCA 358
Cdd:PHA03247 2933 PPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA 2983
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
72-298 |
5.45e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.16 E-value: 5.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 72 SRTCELHPALSLPPRPPRHPEAPQPrgqgSRPQTPRDPQSLYRPQPRGRGGPLRGPASQVGREETQEPRGAQrfrvrdpi 151
Cdd:PHA03247 2892 SRSTESFALPPDQPERPPQPQAPPP----PQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAV-------- 2959
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 152 kPGMFGYGRVPFALPLHRSRRLAHKPGQP-KDSSTAEETLPSQPPSTEPASE--KHSPHMQPPELRAQSRSPSAETPRSG 228
Cdd:PHA03247 2960 -PQPWLGALVPGRVAVPRFRVPQPAPSREaPASSTPPLTGHSLSRVSSWASSlaLHEETDPPPVSLKQTLWPPDDTEDSD 3038
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958750789 229 TAQTEV--PSRTSSAPSDMGIPAPTSSFRDSrSFQGSPEPRMPTSQGAERQPHPFSpvTRSQLSRRHWRPPG 298
Cdd:PHA03247 3039 ADSLFDsdSERSDLEALDPLPPEPHDPFAHE-PDPATPEAGARESPSSQFGPPPLS--ANAALSRRYVRSTG 3107
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
179-348 |
6.81e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 43.54 E-value: 6.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 179 QPKDSSTAEETLPSQPPSTEPASEKHSPHMQPPELRAQSRSPSAETPRSGTAQTEVPSRtSSAPSDMGIPAPTSSFrDSR 258
Cdd:PRK08691 378 QSPSAQTAEKETAAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPVSNQENNDVPPW-EDAPDEAQTAAGTAQT-SAK 455
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 259 SFQGSPEPRMPtsqgaerqphPFSPVTRSQLSRRHWRPPGSPHRSPDGWLPLTRDSSPHWSLFAPSSPTPECSGESeqmr 338
Cdd:PRK08691 456 SIQTASEAETP----------PENQVSKNKAADNETDAPLSEVPSENPIQATPNDEAVETETFAHEAPAEPFYGYG---- 521
|
170
....*....|
gi 1958750789 339 aCSQEPCPPE 348
Cdd:PRK08691 522 -FPDNDCPPE 530
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
84-304 |
1.41e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 42.61 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 84 PPRPPRHPEAPQPRGQGSRPQTP-------RDPQSLYRPQPRGR----------------------GGPLRGPASQVGRE 134
Cdd:PLN03209 351 APSPPIEEEPPQPKAVVPRPLSPytayedlKPPTSPIPTPPSSSpassksvdavakpaepdvvpspGSASNVPEVEPAQV 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 135 ETQEPRGAQRFRVRDPIKPgmfgygrvpfalplhrsrrlahkPGQPkdSSTAEEtlPSQPPSTEPASEKHSPHMQPPELR 214
Cdd:PLN03209 431 EAKKTRPLSPYARYEDLKP-----------------------PTSP--SPTAPT--GVSPSVSSTSSVPAVPDTAPATAA 483
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 215 AQSRSPSAETPRSGT---AQTEVPSRTSSAPSDMGIPAPTSSFRDSRSFQGSPEPRMPTSQG--AERQPHPFSPVTRSQl 289
Cdd:PLN03209 484 TDAAAPPPANMRPLSpyaVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQhhAQPKPRPLSPYTMYE- 562
|
250
....*....|....*
gi 1958750789 290 srrHWRPPGSPHRSP 304
Cdd:PLN03209 563 ---DLKPPTSPTPSP 574
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
82-278 |
3.54e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.51 E-value: 3.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 82 SLPPRPPRHPEAPQPRGQGSRPQTPRDPQSLYRPQPRGRGGPLRGPASQVGREETQEPRGAQRFRVRDPIKPGMFGYGRV 161
Cdd:PRK07764 594 AAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKA 673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 162 PFALPlhrsrrLAHKPGQPKDSSTAEETLPSQPPSTEPASEKHSPHMQPPELRAQSRSPSAETPRSGTAQTEVPSRTSSA 241
Cdd:PRK07764 674 GGAAP------AAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDD 747
|
170 180 190
....*....|....*....|....*....|....*..
gi 1958750789 242 PSDMGIPAPTSSFRDSRSFQGSPEPRMPTSQGAERQP 278
Cdd:PRK07764 748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEE 784
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
169-355 |
3.63e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 41.31 E-value: 3.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 169 RSRRLAHKPGQPKDSSTAEETLPSQPPSTEPASEKHSPhmqPPELRAQSRSPSAETPRSGTAQTEVPSRTSSAPSDMGIP 248
Cdd:PHA03307 93 STLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSP---APDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASS 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 249 A----PTSSFRDSRSFQGSPEPRMPTSQGAERQPHPfSPVTRSQLSRRHWRPPGSPHRSPDGWLPLTRDSSPHW-SLFAP 323
Cdd:PHA03307 170 RqaalPLSSPEETARAPSSPPAEPPPSTPPAAASPR-PPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSeSSGCG 248
|
170 180 190
....*....|....*....|....*....|....*
gi 1958750789 324 SSPTPECSGESEQMRA---CSQEPCPPEQPDPRAL 355
Cdd:PHA03307 249 WGPENECPLPRPAPITlptRIWEASGWNGPSSRPG 283
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
79-300 |
4.67e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.08 E-value: 4.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 79 PALSLPPRPPRHPEAPQPRGQGSRPQTPRDPQSLYRPQPRGRGGPLRG-------------PASQVGREETQEPRGAQRF 145
Cdd:PHA03247 257 PPPVVGEGADRAPETARGATGPPPPPEAAAPNGAAAPPDGVWGAALAGaplalpappdpppPAPAGDAEEEDDEDGAMEV 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 146 RVRDPiKPGMfgygRVPFALPlHRSRRLAHKPGQPKDSSTAEETLPSQPPSTepASEKHSPHMQPPELRA----QSRSPS 221
Cdd:PHA03247 337 VSPLP-RPRQ----HYPLGFP-KRRRPTWTPPSSLEDLSAGRHHPKRASLPT--RKRRSARHAATPFARGpggdDQTRPA 408
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958750789 222 AETPRSGTAQTEVPSrTSSAPSDMGIPAPTSSFRDSRSFQGSPEPRMPTSQGAERQPHPFSPVTRSQLSRRHWRPPGSP 300
Cdd:PHA03247 409 APVPASVPTPAPTPV-PASAPPPPATPLPSAEPGSDDGPAPPPERQPPAPATEPAPDDPDDATRKALDALRERRPPEPP 486
|
|
| PTZ00441 |
PTZ00441 |
sporozoite surface protein 2 (SSP2); Provisional |
746-794 |
6.73e-03 |
|
sporozoite surface protein 2 (SSP2); Provisional
Pssm-ID: 240420 [Multi-domain] Cd Length: 576 Bit Score: 40.33 E-value: 6.73e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1958750789 746 CGHWEissPWSQCSVRCGRGQRSRQ-----VRCVGSNGHEVGKQECASGPPPPP 794
Cdd:PTZ00441 240 CGPWD---EWTPCSVTCGKGTHSRSrpilhEGCTTHMVEECEEEECPVEPEPLP 290
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
174-354 |
8.07e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 40.35 E-value: 8.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 174 AHKPGQPKDSSTAEETLPSQPPSTEPASEKH---SPHMQPPELRAQSRSPSAETPRSGTAQTEVPSRTSSAPSDMGIPAP 250
Cdd:PRK07764 599 GPPAPASSGPPEEAARPAAPAAPAAPAAPAPagaAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAP 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 251 TSSFRDSRSFQGSPEPRMPTSQGAERQPHPfSPVTRSQLSRRHWRPP----GSPHRSPDGWLPLTRD-SSPHWSLFAPSS 325
Cdd:PRK07764 679 AAPPPAPAPAAPAAPAGAAPAQPAPAPAAT-PPAGQADDPAAQPPQAaqgaSAPSPAADDPVPLPPEpDDPPDPAGAPAQ 757
|
170 180
....*....|....*....|....*....
gi 1958750789 326 PTPECSGESEQMRACSQEPCPPEQPDPRA 354
Cdd:PRK07764 758 PPPPPAPAPAAAPAAAPPPSPPSEEEEMA 786
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
170-354 |
8.49e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 39.97 E-value: 8.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 170 SRRLAHKPGQPKDSSTAEETLPSQPPSTEPASEKHSPHMQPPElraqsrsPSAETPRSGTAQTEVPSRTSSAPSDMGIPA 249
Cdd:PRK07764 605 SSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGV-------AAPEHHPKHVAVPDASDGGDGWPAKAGGAA 677
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958750789 250 PTSSfrdsrsfqgspeprMPTSQGAERQPhPFSPVTRSQLSRRHWRPPGSPHRSPdgWLPLTRDSSPHWSLFAPSSPTPE 329
Cdd:PRK07764 678 PAAP--------------PPAPAPAAPAA-PAGAAPAQPAPAPAATPPAGQADDP--AAQPPQAAQGASAPSPAADDPVP 740
|
170 180
....*....|....*....|....*
gi 1958750789 330 CSGESEQMRACSQEPCPPEQPDPRA 354
Cdd:PRK07764 741 LPPEPDDPPDPAGAPAQPPPPPAPA 765
|
|
| TSP_1 |
pfam00090 |
Thrombospondin type 1 domain; |
52-75 |
9.28e-03 |
|
Thrombospondin type 1 domain;
Pssm-ID: 459668 [Multi-domain] Cd Length: 49 Bit Score: 35.09 E-value: 9.28e-03
|
| |
