2FHY: Structure of human liver FPBase complexed with a novel benzoxazole as allosteric inhibitor

PDB ID: 2FHYDownload
MMDB ID: 37747
PDB Deposition Date: 2005/12/27
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 2.95  Å
Source Organism:
Similar Structures:
Biological Unit for 2FHY: tetrameric; determined by author and by software (PISA)
Molecular Components in 2FHY
Label Count Molecule
Proteins (4 molecules)
4
Fructose-1,6-bisphosphatase 1
(Gene symbol: FBP1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
4
2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303