2H6H: Y365F Protein Farnesyltransferase Mutant Complexed with a Farnesylated DDPTASACVLS Peptide Product at 1.8A

PDB ID: 2H6HDownload
MMDB ID: 40989
PDB Deposition Date: 2006/5/31
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2H6H: trimeric; determined by author and by software (PISA)
Molecular Components in 2H6H
Label Count Molecule
Proteins (3 molecules)
1
Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit
Molecule annotation
1
Protein Farnesyltransferase Beta Subunit
Molecule annotation
1
Farnesylated Peptide
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
alpha-D-glucopyranosealpha-D-glucopyranose
2
1
beta-D-fructofuranosebeta-D-fructofuranose
3
1
ACETIC ACIDACETIC ACID
4
1
ZINC IONZINC ION
5
1
FARNESYLFARNESYL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303