2JAV: Human Kinase with pyrrole-indolinone ligand

PDB ID: 2JAVDownload
MMDB ID: 43477
PDB Deposition Date: 2006/11/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 2JAV: monomeric; determined by author and by software (PQS)
Molecular Components in 2JAV
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Nek2
(Gene symbol: NEK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-[(Z)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE5-[(Z)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303