2NO3: Novel 4-anilinopyrimidines as potent JNK1 Inhibitors

PDB ID: 2NO3Download
MMDB ID: 45828
PDB Deposition Date: 2006/10/24
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2NO3: dimeric; determined by author and by software (PISA)
Molecular Components in 2NO3
Label Count Molecule
Proteins (2 molecules)
1
Mitogen-activated Protein Kinase 8
Molecule annotation
1
C-jun-amino-terminal Kinase-interacting Protein 1
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
SULFATE IONSULFATE ION
2
1
2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303