2QA3: Structural Studies Reveal the Inactivation of E. coli L-aspartate aminotransferase by (S)-4,5-amino-dihydro-2-thiophenecarboxylic acid (SADTA) via two mechanisms (at pH6.5)

PDB ID: 2QA3Download
MMDB ID: 61030
PDB Deposition Date: 2007/6/14
Updated in MMDB: 2007/12
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 2QA3: dimeric; determined by author and by software (PISA,PQS)
Molecular Components in 2QA3
Label Count Molecule
Proteins (2 molecules)
2
Aspartate Aminotransferase
(Gene symbol: aspC)
Molecule annotation
Chemicals and Non-standard biopolymers (36 molecules)
1
6
SULFATE IONSULFATE ION
2
2
4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID
3
2
4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE
4
26
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303