2WI3: Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone

PDB ID: 2WI3Download
MMDB ID: 75545
PDB Deposition Date: 2009/5/8
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 2WI3: monomeric; determined by author and by software (PQS)
Molecular Components in 2WI3
Label Count Molecule
Protein (1 molecule)
1
Heat Shock Protein, HSP 90-alpha
(Gene symbol: HSP90AA1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
4-METHYL-6-(METHYLSULFANYL)-1,3,5-TRIAZIN-2-AMINE4-METHYL-6-(METHYLSULFANYL)-1,3,5-TRIAZIN-2-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303