2Z8C: Phosphorylated insulin receptor tyrosine kinase in complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid

PDB ID: 2Z8CDownload
MMDB ID: 65992
PDB Deposition Date: 2007/9/5
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 3.25  Å
Source Organism:
Similar Structures:
Biological Unit for 2Z8C: dimeric; determined by author and by software (PISA)
Molecular Components in 2Z8C
Label Count Molecule
Proteins (2 molecules)
1
Insulin Receptor
(Gene symbol: INSR)
Molecule annotation
1
6-mer Peptide From Insulin Receptor Substrate 1
(Gene symbol: IRS1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
[4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID[4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303