2ZTW: Structure of 3-isopropylmalate dehydrogenase in complex with the inhibitor and NAD+

PDB ID: 2ZTWDownload
MMDB ID: 77268
PDB Deposition Date: 2008/10/10
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.79  Å
Source Organism:
Similar Structures:
Biological Unit for 2ZTW: dimeric; determined by author and by software (PISA)
Molecular Components in 2ZTW
Label Count Molecule
Proteins (2 molecules)
2
3-isopropylmalate Dehydrogenase
(Gene symbol: TTHA1230)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
2
2
(2Z)-2-hydroxy-3-(methylsulfanyl)prop-2-enoic acid(2Z)-2-hydroxy-3-(methylsulfanyl)prop-2-enoic acid
3
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303