3DZY: Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with Rosiglitazone, 9-cis Retinoic Acid and NCOA2 Peptide

PDB ID: 3DZYDownload
MMDB ID: 67636
PDB Deposition Date: 2008/7/30
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3DZY: hexameric; determined by author and by software (PISA)
Molecular Components in 3DZY
Label Count Molecule
Proteins (4 molecules)
1
Retinoic Acid Receptor Rxr-alpha
Molecule annotation
1
Peroxisome Proliferator-activated Receptor Gamma
Molecule annotation
2
Ncoa2 Peptide
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*dcp*dap*dap*dap*dcp*dtp*dap*dgp*dgp*dtp*dcp*dap*dap*dap*dgp*dgp*dtp*dcp*dap*dg)-3')
Molecule annotation
1
DNA (5'-d(*dcp*dtp*dgp*dap*dcp*dcp*dtp*dtp*dtp*dgp*dap*dcp*dcp*dtp*dap*dgp*dtp*dtp*dtp*dg)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
(9cis)-retinoic acid(9cis)-retinoic acid
2
4
ZINC IONZINC ION
3
1
2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL)2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303