3FXI: Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex

PDB ID: 3FXIDownload
MMDB ID: 70004
PDB Deposition Date: 2009/1/21
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3FXI: tetrameric; determined by author and by software (PISA)
Molecular Components in 3FXI
Label Count Molecule
Proteins (4 molecules)
2
Toll-like Receptor 4
(Gene symbol: TLR4)
Molecule annotation
2
Lymphocyte Antigen 96
(Gene symbol: LY96)
Molecule annotation
Chemicals and Non-standard biopolymers (52 molecules)
1
3
2-amino-2-deoxy-alpha-D-glucopyranose2-amino-2-deoxy-alpha-D-glucopyranose
2
4
3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid
3
6
L-glycero-alpha-D-manno-heptopyranoseL-glycero-alpha-D-manno-heptopyranose
4
16
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
5
1
2-amino-2-deoxy-beta-D-glucopyranose2-amino-2-deoxy-beta-D-glucopyranose
6
8
3-HYDROXY-TETRADECANOIC ACID3-HYDROXY-TETRADECANOIC ACID
7
2
LAURIC ACIDLAURIC ACID
8
2
MYRISTIC ACIDMYRISTIC ACID
9
8
PHOSPHATE IONPHOSPHATE ION
10
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303