3H9K: Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry

PDB ID: 3H9KDownload
MMDB ID: 81960
PDB Deposition Date: 2009/4/30
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 3H9K: dimeric; determined by author and by software (PISA)
Molecular Components in 3H9K
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
(Gene symbol: TYMS)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303