3H9R: Crystal structure of the kinase domain of type I activin receptor (ACVR1) in complex with FKBP12 and dorsomorphin

PDB ID: 3H9RDownload
MMDB ID: 73075
PDB Deposition Date: 2009/4/30
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 3H9R: dimeric; determined by software (PISA)
Molecular Components in 3H9R
Label Count Molecule
Proteins (2 molecules)
1
Activin Receptor Type-1
(Gene symbol: ACVR1)
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase Fkbp1a
(Gene symbol: FKBP1A)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
2
5
SULFATE IONSULFATE ION
3
3
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303