3IMX: Crystal Structure of human glucokinase in complex with a synthetic activator

PDB ID: 3IMXDownload
MMDB ID: 77215
PDB Deposition Date: 2009/8/11
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3IMX: monomeric; determined by software (PISA)
Molecular Components in 3IMX
Label Count Molecule
Protein (1 molecule)
1
Glucokinase
(Gene symbol: GCK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
alpha-D-glucopyranosealpha-D-glucopyranose
2
1
(2R)-3-cyclopentyl-N-(5-methoxy[1,3]thiazolo[5,4-b]pyridin-2-yl)-2-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}propanamide(2R)-3-cyclopentyl-N-(5-methoxy[1,3]thiazolo[5,4-b]pyridin-2-yl)-2-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}propanamide
3
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303