3OEZ: crystal structure of the L317I mutant of the chicken c-Src tyrosine kinase domain complexed with imatinib

PDB ID: 3OEZDownload
MMDB ID: 92720
PDB Deposition Date: 2010/8/13
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 3OEZ: monomeric; determined by author and by software (PISA)
Molecular Components in 3OEZ
Label Count Molecule
Protein (1 molecule)
1
Proto-oncogene Tyrosine-protein Kinase SRC
(Gene symbol: SRC)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
2
1
ACETATE IONACETATE ION
3
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303