3OT8: X-ray crystal structure of compound 17r bound to human Chk1 kinase domain

PDB ID: 3OT8Download
MMDB ID: 86142
PDB Deposition Date: 2010/9/10
Updated in MMDB: 2010/12
Experimental Method:
x-ray diffraction
Resolution: 1.6455  Å
Source Organism:
Similar Structures:
Biological Unit for 3OT8: monomeric; determined by author and by software (PISA)
Molecular Components in 3OT8
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Chk1
(Gene symbol: CHEK1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
N-(3-methylisothiazol-5-yl)-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3R)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amineN-(3-methylisothiazol-5-yl)-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3R)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
2
3
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303