3RQD: Ideal Thiolate-Zinc Coordination Geometry in Depsipeptide Binding to Histone Deacetylase 8

PDB ID: 3RQDDownload
MMDB ID: 92908
PDB Deposition Date: 2011/4/28
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.143  Å
Source Organism:
Similar Structures:
Biological Unit for 3RQD: trimeric; determined by author and by software (PISA)
Molecular Components in 3RQD
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 8
(Gene symbol: HDAC8)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
CD
2
Largazole
1
2
ZINC IONZINC ION
2
4
POTASSIUM IONPOTASSIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303