3UXM: Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation

PDB ID: 3UXMDownload
MMDB ID: 96945
PDB Deposition Date: 2011/12/5
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 3UXM: monomeric; determined by author
Molecular Components in 3UXM
Label Count Molecule
Protein (1 molecule)
1
Thymidylate Kinase
(Gene symbol: tmk)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
1
5'-deoxy-5'-fluorothymidine5'-deoxy-5'-fluorothymidine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303