3ZRK: Identification of 2-(4-pyridyl)thienopyridinones as GSK-3beta inhibitors

PDB ID: 3ZRKDownload
MMDB ID: 92072
PDB Deposition Date: 2011/6/16
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.37  Å
Source Organism:
Similar Structures:
Biological Unit for 3ZRK: dimeric; determined by author and by software (PISA)
Molecular Components in 3ZRK
Label Count Molecule
Proteins (2 molecules)
1
Glycogen Synthase Kinase-3 Beta
(Gene symbol: GSK3B)
Molecule annotation
1
Proto-oncogene Frat1
(Gene symbol: FRAT1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
3
SULFATE IONSULFATE ION
2
2
GLYCEROLGLYCEROL
3
1
2-(4-PYRIDINYL)FURO[3,2-C]PYRIDIN-4(5H)-ONE2-(4-PYRIDINYL)FURO[3,2-C]PYRIDIN-4(5H)-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303