4AJR: 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, magnesium(II) and NADPH - The product complex

PDB ID: 4AJRDownload
MMDB ID: 104487
PDB Deposition Date: 2012/2/17
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.687  Å
Source Organism:
Similar Structures:
Biological Unit for 4AJR: dimeric; determined by author and by software (PISA)
Molecular Components in 4AJR
Label Count Molecule
Proteins (2 molecules)
2
Isocitrate Dehydrogenase [nadp]
(Gene symbol: icd)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATEBETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE
2
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
3
2
2-OXOGLUTARIC ACID2-OXOGLUTARIC ACID
4
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303