4AW5: Complex of the EphB4 kinase domain with an oxindole inhibitor

PDB ID: 4AW5Download
MMDB ID: 101644
PDB Deposition Date: 2012/5/31
Updated in MMDB: 2012/08
Experimental Method:
x-ray diffraction
Resolution: 2.33  Å
Source Organism:
Similar Structures:
Biological Unit for 4AW5: monomeric; determined by author and by software (PISA)
Molecular Components in 4AW5
Label Count Molecule
Protein (1 molecule)
1
Ephrin Type-b Receptor 4
(Gene symbol: EPHB4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(3Z)-5-[(1-ethylpiperidin-4-yl)amino]-3-[(5-methoxy-1H-benzimidazol-2-yl)(phenyl)methylidene]-1,3-dihydro-2H-indol-2-one(3Z)-5-[(1-ethylpiperidin-4-yl)amino]-3-[(5-methoxy-1H-benzimidazol-2-yl)(phenyl)methylidene]-1,3-dihydro-2H-indol-2-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303