4CI1: Structure of the DDB1-CRBN E3 ubiquitin ligase bound to thalidomide

PDB ID: 4CI1Download
MMDB ID: 173977
PDB Deposition Date: 2013/12/5
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.98  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 4CI1: dimeric; determined by author and by software (PISA)
Molecular Components in 4CI1
Label Count Molecule
Proteins (2 molecules)
1
DNA Damage-binding Protein 1
Molecule annotation
1
Protein Cereblon
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
S-ThalidomideS-Thalidomide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303