4FDH: Structure of human aldosterone synthase, CYP11B2, in complex with fadrozole

PDB ID: 4FDHDownload
MMDB ID: 107169
PDB Deposition Date: 2012/5/28
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.71  Å
Source Organism:
Similar Structures:
Biological Unit for 4FDH: hexameric; determined by author and by software (PISA)
Molecular Components in 4FDH
Label Count Molecule
Proteins (6 molecules)
6
Cytochrome P450 11b2, Mitochondrial
(Gene symbol: CYP11B2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
6
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
6
4-[(5R)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrile4-[(5R)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303