4FEE: High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal B

PDB ID: 4FEEDownload
MMDB ID: 100766
PDB Deposition Date: 2012/5/30
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.13  Å
Source Organism:
Similar Structures:
Biological Unit for 4FEE: tetrameric; determined by author and by software (PISA)
Molecular Components in 4FEE
Label Count Molecule
Proteins (4 molecules)
4
Pyruvate Oxidase
Molecule annotation
Chemicals and Non-standard biopolymers (36 molecules)
1
4
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
2
12
GLYCEROLGLYCEROL
3
8
PYRUVIC ACIDPYRUVIC ACID
4
4
PHOSPHATE IONPHOSPHATE ION
5
4
2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE
6
4
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303