4I4T: Crystal structure of tubulin-RB3-TTL-Zampanolide complex

PDB ID: 4I4TDownload
MMDB ID: 106953
PDB Deposition Date: 2012/11/28
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 4I4T: hexameric; determined by author
Molecular Components in 4I4T
Label Count Molecule
Proteins (6 molecules)
2
Tubulin Alpha-1b Chain
Molecule annotation
2
Tubulin Beta-2b Chain
Molecule annotation
1
Stathmin-4
Molecule annotation
1
Tubulin Tyrosine Ligase, TTL
Molecule annotation
Chemicals and Non-standard biopolymers (26 molecules)
1
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
6
MAGNESIUM IONMAGNESIUM ION
3
4
CALCIUM IONCALCIUM ION
4
1
CHLORIDE IONCHLORIDE ION
5
7
GLYCEROLGLYCEROL
6
2
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
7
1
TYROSINETYROSINE
8
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
9
1
(2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamide(2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamide
10
1
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303