4JII: Crystal Structure Of AKR1B10 Complexed With NADP+ And Zopolrestat

PDB ID: 4JIIDownload
MMDB ID: 114495
PDB Deposition Date: 2013/3/6
Updated in MMDB: 2013/11
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 4JII: monomeric; determined by author and by software (PISA)
Molecular Components in 4JII
Label Count Molecule
Protein (1 molecule)
1
Aldo-keto Reductase Family 1 Member B10
(Gene symbol: AKR1B10)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID
3
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303