4PO6: Crystal structure of the human TYK2 FERM and SH2 domains with an IFNAR1 intracellular peptide

PDB ID: 4PO6Download
MMDB ID: 118907
PDB Deposition Date: 2014
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 1.99  Å
Source Organism:
Similar Structures:
Biological Unit for 4PO6: dimeric; determined by author and by software (PISA)
Molecular Components in 4PO6
Label Count Molecule
Proteins (2 molecules)
1
Non-receptor Tyrosine-protein Kinase Tyk2
(Gene symbol: TYK2)
Molecule annotation
1
Interferon Alpha/beta Receptor 1
(Gene symbol: IFNAR1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303