4RER: Crystal structure of the phosphorylated human alpha1 beta2 gamma1 holo-AMPK complex bound to AMP and cyclodextrin

PDB ID: 4RERDownload
MMDB ID: 236038
PDB Deposition Date: 2014/9/23
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 4.047  Å
Source Organism:
Similar Structures:
Biological Unit for 4RER: trimeric; determined by author and by software (PISA)
Molecular Components in 4RER
Label Count Molecule
Proteins (3 molecules)
1
5'-amp-activated Protein Kinase Catalytic Subunit Alpha-1
(Gene symbol: PRKAA1)
Molecule annotation
1
5'-amp-activated Protein Kinase Subunit Beta-2
(Gene symbol: PRKAB2)
Molecule annotation
1
5'-amp-activated Protein Kinase Subunit Gamma-1
(Gene symbol: PRKAG1)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
7
alpha-D-glucopyranosealpha-D-glucopyranose
2
1
STAUROSPORINESTAUROSPORINE
3
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
4
3
ADENOSINE MONOPHOSPHATEADENOSINE MONOPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303