5D6F: Structure of human methionine aminopeptidase-2 complexed with spiroepoxytriazole inhibitor (+)-31b

PDB ID: 5D6FDownload
MMDB ID: 135475
PDB Deposition Date: 2015/8/12
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 5D6F: monomeric; determined by author and by software (PISA)
Molecular Components in 5D6F
Label Count Molecule
Protein (1 molecule)
1
Methionine Aminopeptidase 2
(Gene symbol: METAP2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
(4S,7R)-7-hydroxy-1-(4-methoxybenzyl)-7-methyl-4,5,6,7-tetrahydro-1H-benzotriazol-4-yl propan-2-ylcarbamate(4S,7R)-7-hydroxy-1-(4-methoxybenzyl)-7-methyl-4,5,6,7-tetrahydro-1H-benzotriazol-4-yl propan-2-ylcarbamate
2
1
COBALT (II) IONCOBALT (II) ION
3
2
TERTIARY-BUTYL ALCOHOLTERTIARY-BUTYL ALCOHOL
4
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303