5DC8: Crystal structure of H142A-Y306F HDAC8 in complex with a tetrapeptide substrate

PDB ID: 5DC8Download
MMDB ID: 136235
PDB Deposition Date: 2015/8/23
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5DC8: trimeric; determined by author and by software (PISA)
Molecular Components in 5DC8
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 8
(Gene symbol: HDAC8)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
CD
2
Fluor-de-Lys tetrapeptide assay substrate
1
2
ZINC IONZINC ION
2
4
POTASSIUM IONPOTASSIUM ION
3
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303