5I75: X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central site and Br-citalopram at the allosteric site

PDB ID: 5I75Download
MMDB ID: 138434
PDB Deposition Date: 2016/2/16
Updated in MMDB: 2016/05
Experimental Method:
x-ray diffraction
Resolution: 3.49  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 5I75: pentameric; determined by author and by software (PISA)
Molecular Components in 5I75
Label Count Molecule
Proteins (5 molecules)
1
Sodium-dependent Serotonin Transporter
Molecule annotation
2
8B6 Antibody, Heavy Chain
Molecule annotation
2
8B6 Antibody, Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
2
2
N-ACETYL-D-GLUCOSAMINEN-ACETYL-D-GLUCOSAMINE
3
1
CHOLESTEROLCHOLESTEROL
4
1
TETRADECANETETRADECANE
5
1
(1S)-1-(4-bromophenyl)-1-[3-(dimethylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile(1S)-1-(4-bromophenyl)-1-[3-(dimethylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile
6
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303