5IYD: Human core-PIC in the initial transcribing state (no IIS)

PDB ID: 5IYDDownload
MMDB ID: 139393
PDB Deposition Date: 2016/3/24
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5IYD: 23-meric; determined by author
Molecular Components in 5IYD
Label Count Molecule
Proteins (20 molecules)
1
DNA-directed RNA Polymerase II Subunit Rpb1
(Gene symbol: POLR2A)
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb2
(Gene symbol: POLR2B)
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb3
(Gene symbol: POLR2C)
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb4
(Gene symbol: POLR2D)
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb5
(Gene symbol: POLR2E)
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb6
(Gene symbol: POLR2F)
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb7
(Gene symbol: POLR2G)
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb8
(Gene symbol: POLR2H)
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb9
(Gene symbol: POLR2I)
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb10
(Gene symbol: POLR2L)
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb11-a
(Gene symbol: POLR2J)
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb12
(Gene symbol: POLR2K)
Molecule annotation
1
Transcription Initiation Factor IIB
(Gene symbol: GTF2B)
Molecule annotation
1
Transcription Initiation Factor IIA Subunit 1
(Gene symbol: GTF2A1)
Molecule annotation
1
Transcription Initiation Factor IIA Subunit 2
(Gene symbol: GTF2A2)
Molecule annotation
1
Tata-box-binding Protein
(Gene symbol: TBP)
Molecule annotation
1
General Transcription Factor IIE Subunit 1
(Gene symbol: GTF2E1)
Molecule annotation
1
Transcription Initiation Factor IIE Subunit Beta
(Gene symbol: GTF2E2)
Molecule annotation
1
General Transcription Factor IIF Subunit 1
(Gene symbol: GTF2F1)
Molecule annotation
1
General Transcription Factor IIF Subunit 2
(Gene symbol: GTF2F2)
Molecule annotation
Nucleotides(3 molecules)
1
Scp-x
Molecule annotation
1
Scp-y
Molecule annotation
1
RNA
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
2
MAGNESIUM ION (Link to PubChem not yet available)MAGNESIUM ION
2
11
ZINC ION (Link to PubChem not yet available)ZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303