5Q1E: Ligand binding to FARNESOID-X-RECEPTOR

PDB ID: 5Q1EDownload
MMDB ID: 152464
PDB Deposition Date: 2017/5/31
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 5Q1E: dimeric; determined by author and by software (PISA)
Molecular Components in 5Q1E
Label Count Molecule
Proteins (2 molecules)
1
Bile Acid Receptor
(Gene symbol: NR1H4)
Molecule annotation
1
Coactivator Peptide Src-1 HD3
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-bromo-1-{[4-(1H-tetrazol-5-yl)phenyl]methyl}-1'-(thiophene-2-sulfonyl)spiro[indole-3,4'-piperidin]-2(1H)-one5-bromo-1-{[4-(1H-tetrazol-5-yl)phenyl]methyl}-1'-(thiophene-2-sulfonyl)spiro[indole-3,4'-piperidin]-2(1H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303