5V3H: Crystal structure of SMYD2 with SAM and EPZ033294

PDB ID: 5V3HDownload
MMDB ID: 161229
PDB Deposition Date: 2017/3/7
Updated in MMDB: 2018/06
Experimental Method:
x-ray diffraction
Resolution: 2.69  Å
Source Organism:
Similar Structures:
Biological Unit for 5V3H: monomeric; determined by author and by software (PISA)
Molecular Components in 5V3H
Label Count Molecule
Protein (1 molecule)
1
N-lysine Methyltransferase Smyd2
(Gene symbol: SMYD2)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
2
3
ZINC IONZINC ION
3
2
N-[1-({1-[(4-chlorophenyl)methyl]-1H-pyrazol-4-yl}methyl)azetidin-3-yl]-1-cyclopropyl-1H-1,2,3-triazole-4-carboxamideN-[1-({1-[(4-chlorophenyl)methyl]-1H-pyrazol-4-yl}methyl)azetidin-3-yl]-1-cyclopropyl-1H-1,2,3-triazole-4-carboxamide
4
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303